Topic:Clinical Study
Clinical studies in equine research involve the systematic investigation of health and disease in horses through structured scientific methods. These studies aim to evaluate the safety and efficacy of treatments, understand disease mechanisms, and improve veterinary care practices. Clinical studies can include randomized controlled trials, observational studies, and case-control studies. They may focus on various aspects such as pharmacokinetics, therapeutic interventions, and diagnostic techniques. This page compiles peer-reviewed research studies and scholarly articles that explore the design, implementation, and findings of clinical studies in equine medicine, providing insights into their impact on horse health and veterinary practices.
Mandibular fracture and fracture repair in a 26 year old Arab horse. In this study the treatment of a mandibular fracture in a 26 year old Arab horse, the history during the subsequent 4 years and the anatomical post-mortem findings are presented and described.
The use of sclerosing agents in tendon repair of racehorses. Most practitioners will have experienced the
frustration encountered in the treatment of sprains
of the flexor tendons and suspensory ligaments
of racehorses. After apparent recovery, the
damaged structure will often break down again
when the horse returns to hard training. Milne
(1960), Reed (1962), Jubb and Kennedy (1963)
and Hickman (1964) have written detailed ac-
counts of the pathology of tendon injuries and the
mechanism of repair of tendon tissue. These
writers substantiate that when a tendon is
sprained, there is a tearing or rupture of some of
the tendon fibres, varying i...
Tissue distribution of sulfadimethoxine and sulfamonomethoxine in horses after intravenous injection. The author has already reported on the time course of blood level of sulfonamides in horses at various dose schedules3). The present paper is concerned with the tissue distri-bution of sulfadimethoxine and sulfamonomethoxine in horses. The distribution of sulfonamides has been reported by KoNDol) in experimental animals, in which the concentrations of these drugs in the kidney, liver, lung and spleen were found to be close to the blood level. Many investigators ascribed the low concen-tration of sulfonamides in the spinal fluid to the existence of a blood-brain barrier, and also observed that ...
The resolution of mixtures of viable mammalian cells into homogeneous fractions by zonal centrifugation. Large-scale separation of mixtures of mammalian cells was obtained with the A-1X zonal centrifuge rotor and density gradients consisting of Ficoll dissolved in modified Eagle's MEM suspension-culture medium. The cells remained viable as tested by plating efficiency or by motility observed with time-lapse photography. Rabbit thymocyte and HeLa cell mixtures were separated with 99 and 89 per cent purity, respectively. Mixtures of thymocytes and suspension-cultured, human acute leukemia cells (Roswell Park strain LKID) were separated with 93 and 91% purity, respectively. HeLa cells were isolated ...
Etiology and pathogenesis of so-called mucoid degeneration of the nasal conchae in the horse. Following a description of the histopathology of so-called mucoid degeneration of the nasal conchae in the horse, the authors conclude that the morphologic nature of the disease is osteodystrophia fibrosa. The lesions are believed to be expressions of nutritional secondary hyperparathyroidism.