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Topic:Disease Diagnosis

Disease diagnosis in horses involves the identification and characterization of illnesses through various diagnostic methods and tools. This process is essential for effective veterinary care and management of equine health. Techniques used in diagnosing diseases in horses include clinical examinations, laboratory tests, imaging modalities such as ultrasonography and radiography, and molecular diagnostics. Blood tests are frequently utilized to assess parameters such as complete blood count and biochemical profiles, which can indicate underlying health issues. Additionally, advancements in genetic testing and biomarker identification have enhanced the ability to detect specific diseases early. This page aggregates peer-reviewed research studies and scholarly articles that explore diagnostic methodologies, their applications, and their impact on equine health management.
Pneumonia, lung abscesses and pleuritis in adult horses: a review of 51 cases.
Equine veterinary journal    May 1, 1989   Volume 21, Issue 3 175-180 doi: 10.1111/j.2042-3306.1989.tb02135.x
Mair TS, Lane JG.Case records are reviewed of 51 adult horses in which a diagnosis of pneumonia, pulmonary abscess or pleuritis had been made. Forty-five horses were afflicted with pneumonia and/or pulmonary abscesses; in 11 of these the infection was primary, whereas in 34 it was secondary to another disease process (inhalation of food or saliva, thoracic trauma, generalised infection, airway disease, neoplasia or thromboembolism). Of the 11 horses with primary pulmonary infections, 10 appeared to be associated with a previous episode of stress; this took the form of long distance travel in eight cases. There...
(+)-[3H]-PN 200-110 binding to cell membranes and intact strips of portal vein smooth muscle: characterization and modulation by membrane potential and divalent cations.
British journal of pharmacology    May 1, 1989   Volume 97, Issue 1 256-262 doi: 10.1111/j.1476-5381.1989.tb11949.x
Dacquet C, Loirand G, Rakotoarisoa L, Mironneau C, Mironneau J.1. Specific binding of the calcium-antagonist dihydropyridine derivative, (+)-[3H]-PN 200-110 (isradipine), to cell membranes of equine portal vein smooth muscle was compared with binding to intact strips isolated from rat portal veins. 2. Specific binding to vascular smooth muscle membranes was of high affinity, saturable and reversible. The dissociation constant obtained from association and dissociation kinetics of (+)-[3H]-PN 200-110 was similar to that obtained from equilibrium binding and competition experiments. 3. Specific binding of (+)-[3H]-PN 200-110 was completely displaced by unla...
Description of an epizootic and persistence of Streptococcus equi infections in horses.
Journal of the American Veterinary Medical Association    May 1, 1989   Volume 194, Issue 9 1281-1286 
Sweeney CR, Benson CE, Whitlock RH, Meirs DA, Barningham SO, Whitehead SC, Cohen D.The age-specific attack rates of Streptococcus equi infections of the upper respiratory tract and lymph nodes (strangles) in horses for the different age groups were 17.6% for broodmares, 47.5% for 1-year-old horses, and 37.5% for foals. Streptococcus equi was isolated from nasal, pharyngeal, or lymph node specimens in 31 (60.8%) of 51 sick horses. A male 1-year-old horse, shipped from Kentucky to farm A, was considered to be the index case. Six (19.4%) of 31 horses with strangles remained as shedders of S equi after clinical signs of the disease had ended. Shedders of S equi were not identifi...
Tubuloreticular inclusions in equine connective tissue neoplasms.
Journal of comparative pathology    May 1, 1989   Volume 100, Issue 4 449-452 doi: 10.1016/0021-9975(89)90011-x
Madewell BR, Munn RJ.Abnormal irregularly branched and anastomosing tubules within cisternae of endoplasmic reticulum were observed by transmission electron microscopy in tumour cells comprising connective tissue neoplasms (sarcoids) from three horses and a mule. These tubuloreticular inclusions were also observed in cultured tumour cells from one of these horses examined, but were not detected in fibroblasts (fibrocytes), epidermis, or vascular endothelial cells in skin biopsy specimens from five clinically healthy horses, nor in one additional equine connective tissue neoplasm.
Removal of a retropharyngeal foreign body in a horse, with the aid of ultrasonography during surgery.
Journal of the American Veterinary Medical Association    May 1, 1989   Volume 194, Issue 9 1315-1316 
French DA, Pharr JW, Fretz PB.Diagnostic ultrasonography was used during surgery to assist in the removal of a piece of wire from the retropharyngeal region. A 3-year-old Quarter Horse mare was referred with dysphagia of 2 days' duration. Radiography revealed a 9-cm piece of wire located caudodorsal to the larynx. A ventral surgical approach was performed, dissecting along the right side of the larynx and trachea. The surgical field was filled with 0.85% sterile physiologic saline solution. A 5 MHz-mm sector scanner probe immersed in the fluid was able to locate the wire and facilitate the direction and depth of dissection...
Rectal tears in the horse: an analysis of 35 cases.
Equine veterinary journal    May 1, 1989   Volume 21, Issue 3 186-188 doi: 10.1111/j.2042-3306.1989.tb02138.x
Watkins JP, Taylor TS, Schumacher J, Taylor JR, Gillis JP.The records of 35 horses with Grade 3 or 4 rectal tears, presented to the Veterinary Medical Center at Texas A & M University over a five year period, were reviewed. Grade 3 tears were sub-classified according to whether the remaining tissue was serosa (Grade 3a) or mesorectum (Grade 3b). Five horses were destroyed on presentation and 30 were treated by primary suture closure (8 horses), faecal diversion alone (9 horses) or in combination with suture closure (11 horses) and packing of the tear with medicated gauze sponges (two horses). Faecal diversion was achieved with a temporary indwell...
[The possibility of using equine serum albumin in place of bovine serum albumin and ovalbumin in radioimmunological and immunoenzyme analyses and in virological practice].
Zhurnal mikrobiologii, epidemiologii i immunobiologii    May 1, 1989   Issue 5 47-50 
Kolmakova MV, Kuskova ZR, Ratner GM, Laptakova LM.Horse serum albumin has been shown to meet the requirements to protein preparations for microanalysis and thus to be suitable for use in kits of reagents for the radioimmunological determination of insulin and myoglobin, for the determination of tick-borne encephalitis virus antigen by the method of the enzyme immunoassay and for the stabilization of proteins in the hemagglutination test and the hemagglutination inhibition test.
An unusual cause of increasing airway pressure during anesthesia.
Veterinary surgery : VS    May 1, 1989   Volume 18, Issue 3 239-241 doi: 10.1111/j.1532-950x.1989.tb01078.x
Klein LV, Wilson DV.A mare with a thoracic laceration was anesthetized with halothane-O2 for surgical repair. Shortly after initiation of controlled ventilation, inspiratory plateau pressure began to increase. The increase in pressure continued despite decreasing the tidal volume. Tension pneumothorax was suspected, but because arterial PCO2 and PO2 were normal, the anesthetic apparatus was examined. Excess gas continued to exit through the bellows pop-off valve even when the fresh gas flow was turned off. It was determined that driving gas from the ventilator was entering the breathing circuit through a hole in ...
[The “weaving” of horses].
DTW. Deutsche tierarztliche Wochenschrift    May 1, 1989   Volume 96, Issue 5 248-255 
Sambraus HH, Radtke K.Studies were made on 27 horses which were known to weave. They were stallions, mares and geldings between the ages of 3 and 22 years. The horses were individually observed for several days in their habitual surroundings. A period, in which a horse makes pauses of not more than ten minutes, is considered a weaving phase. Shorter pauses subdivide the weaving phase into weaving series. The basic unit of weaving is the weaving displacement, i.e. the head movement between the turning points. The number of daily weaving displacements of the horses examined varied from less than 400 up to almost 18,0...
Identification of the gB homologues of equine herpesvirus types 1 and 4 as disulphide-linked heterodimers and their characterization using monoclonal antibodies.
The Journal of general virology    May 1, 1989   Volume 70 ( Pt 5) 1161-1172 doi: 10.1099/0022-1317-70-5-1161
Meredith DM, Stocks JM, Whittaker GR, Halliburton IW, Snowden BW, Killington RA.Equine herpesvirus types 1 and 4 (EHV-1 and EHV-4) labelled with [14C]glucosamine were purified from infected cell culture medium and profiles of their structural proteins were obtained that enabled identification of the major glycoproteins. Nine glycosylated polypeptides were identified for each virus. Preparations of the purified viruses each contained a glycoprotein which was linked by disulphide bonds, as determined by diagonal gel electrophoresis under reducing/non-reducing conditions. High Mr forms of this glycoprotein were detected for EHV-1 when the sample was not heated. The EHV-1 pro...
Toxicity of field samples and Fusarium moniliforme from feed associated with equine-leucoencephalomalacia.
Archives of environmental contamination and toxicology    May 1, 1989   Volume 18, Issue 3 439-442 doi: 10.1007/BF01062371
Vesonder R, Haliburton J, Golinski P.Feed samples of corn, pelleted feed, and oats associated with equine leucoencephalomalacia (ELEM) were obtained from North Carolina, Illinois, Indiana, and Oklahoma. These samples contained a high colony density of Fusarium moniliforme Sheldon which ranged from 64 to 87% of the total fungi. Fifty-nine F. moniliforme strains were isolated. Isolates of F. moniliforme in feed samples from Illinois, Indiana, and Oklahoma were cultured on corn. The fermented corn, mixed with regular feed and fed to one-day-old ducklings, effected a high mortality coefficient (average 55%). Methanol extracts of corn...
Detection of hypogammaglobulinaemia in neonatal foals using the glutaraldehyde coagulation test.
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B    May 1, 1989   Volume 36, Issue 3 168-174 doi: 10.1111/j.1439-0450.1989.tb00587.x
Saikku A, Koskinen E, Sandholm M.The glutaraldehyde coagulation test was adapted to foal serum to determine adequacy of the colostral-intestinal transfusion of IgG. The test is performed simply by mixing one volume of reagent with 10 volumes of serum and observing the coagulation time. The required glutaraldehyde concentration was established for various threshold levels of IgG as determined by radial immunodiffusion. The analysis consisted of 140 serum samples from foals. Sera with low IgG levels require high glutaraldehyde concentrations and vice versa. The 4 g/l threshold generally accepted for IgG adequacy, was achieved a...
Equine herpesvirus outbreaks.
The Veterinary record    April 29, 1989   Volume 124, Issue 17 471 doi: 10.1136/vr.124.17.471-d
Frank C.No abstract available
EHV-1: a recurrent problem.
The Veterinary record    April 29, 1989   Volume 124, Issue 17 443-444 doi: 10.1136/vr.124.17.443
No abstract available
The preparation and biochemical characterization of intact capsids of equine infectious anemia virus.
Biochemical and biophysical research communications    April 28, 1989   Volume 160, Issue 2 486-494 doi: 10.1016/0006-291x(89)92459-5
Roberts MM, Oroszlan S.Capsids of equine infectious anemia virus have been isolated as cone-shaped particles 60 x 120 nm in size. Detergent treatment of whole virus followed by two cycles of rate-zonal centrifugation in Ficoll produces these capsids in a yield of approximately 10%. The major protein components are the gag-encoded p11 nucleocapsid protein and p26 capsid protein, which are present in equimolar amounts. Substantial cleavage of p11 to p6 and p4 can be observed under conditions where the viral protease packaged in the capsid is enzymatically active.
Fragments of nasogastric tubes as esophageal foreign bodies in two horses.
Journal of the American Veterinary Medical Association    April 15, 1989   Volume 194, Issue 8 1068-1070 
Baird AN, True CK.Two horses were referred with fragments of nasogastric tubes as esophageal foreign bodies. Radiography and endoscopy were used to identify the location of the fragments. Portions of the tubes were retrieved by esophagotomy in 1 horse and by manual examination of the oral cavity in the other. Both tubes were friable in focal areas, but were quite pliable over most of the length of the tube.
Synovial hernia as a possible complication of arthroscopic surgery in a horse.
Journal of the American Veterinary Medical Association    April 15, 1989   Volume 194, Issue 8 1071-1072 
Wilson DG.A 3-year-old Standardbred gelding was referred for evaluation of a fluctuant swelling that developed over the dorsum of the carpus subsequent to arthroscopic surgery on that carpus. A synovial hernia was diagnosed and surgically repaired. Although complications secondary to arthroscopy are rare, synovial herniation can develop after arthroscopic surgery. The condition must be differentiated from the more common true bursitis or false bursitis that is commonly referred to as a hygroma.
Bilateral eyelid swelling attributable to lymphosarcoma in a horse.
Journal of the American Veterinary Medical Association    April 1, 1989   Volume 194, Issue 7 939-942 
Murphy CJ, Lavoie JP, Groff J, Hacker D, Pryor P, Bellhorn RW.Bilateral swelling of upper and lower eyelids was caused by lymphocytic infiltration in an 8-year-old Thoroughbred mare. The condition worsened with pregnancy and became associated with subcutaneous dissemination of lymphosarcoma at distant sites.
Experimental trichinellosis in horses: biological and parasitological evaluation.
Veterinary parasitology    April 1, 1989   Volume 31, Issue 1 19-36 doi: 10.1016/0304-4017(89)90005-8
Soule C, Dupouy-Camet J, Georges P, Ancelle T, Gillet JP, Vaissaire J, Delvigne A, Plateau E.Three groups of three horses each were, respectively, infected with 5000, 20,000 and 50,000 larvae of Trichinella spiralis. The strain used was isolated from a human biopsy during horsemeat-related outbreaks of trichinellosis in France. Transient muscular disorders were only observed in two of the horses infected with 50,000 larvae but none of the horses had fever. A significant increase in blood eosinophils was noticed in 5 horses. Serum LDH, aldolase and CPK peaked at the fifth week post-infection. Specific IgG assayed by indirect immunofluorescence and ELISA, appeared 2-5 weeks post-infecti...
A new Papulaspora species from the infected eye of a horse: Papulaspora equi sp. nov.
Mycopathologia    April 1, 1989   Volume 106, Issue 1 35-39 doi: 10.1007/BF00436924
Shadomy HJ, Dixon DM.An unusual fungus, probably traumatically introduced into the eye of a horse while grazing, was studied on various mycological media. Upon examination of colonies the organism produced bulbils and clearly exhibited the characteristics of a new species of Papulaspora, P. equi Shadomy & Dixon.
Pathomorphological aspects of extremely small thymuses occurring spontaneously in Thoroughbred foals.
Nihon juigaku zasshi. The Japanese journal of veterinary science    April 1, 1989   Volume 51, Issue 2 437-440 doi: 10.1292/jvms1939.51.437
Oikawa M, Yoshihara T, Kaneko M.No abstract available
Congenital malignant melanoma in two foals.
Journal of the American Veterinary Medical Association    April 1, 1989   Volume 194, Issue 7 945-947 
Cox JH, DeBowes RM, Leipold HW.Two cases of congenital malignant melanomas in horses are described in this report. In each case, wide surgical excision of the mass was performed; no recurrence or metastasis was detected after a minimum of 15 months' follow-up. Melanomas are among the most common neoplasms of horses, but they typically develop in gray horses greater than 6 years old.
Equine giant cell tumor of soft tissues.
The Cornell veterinarian    April 1, 1989   Volume 79, Issue 2 173-177 
Hamir AN.During a routine necropsy examination of a 4-year-old standardbred mare, a well-demarcated dermal mass was seen near the right elbow. Grossly, the mass consisted of multifocal variably sized areas of dark brown, firm material that was separated by thin white septa. Histologically, within the individual compartments, there were numerous multinucleated giant cells, macrophages, and free erythrocytes. A diagnosis of giant cell tumor of soft tissues was made.
Simple nonrebreathing valves for use with large mammals. Gallivan GJ, Bignell W, McDonell WN, Whiting TL.Two simple nonrebreathing valves suitable for use with large mammals are described. These valves can be constructed in a reasonably well equipped workshop using materials that are readily available. The resistive pressure of both valves is less than 0.1 kPa at flow rates up to 15 L.s-1. Their main limitation is a relatively large dead space, although the dead space of valve B (290 mL) is less than the dead space of some commercially available valves. Healthy adult horses and cows compensate for the increased dead space by an increase in tidal volume.
Regenerative anemia in horses.
Journal of the American Veterinary Medical Association    April 1, 1989   Volume 194, Issue 7 860 
Morris DD.No abstract available
The treatment of laminitis in horses.
The Veterinary clinics of North America. Equine practice    April 1, 1989   Volume 5, Issue 1 73-108 doi: 10.1016/s0749-0739(17)30605-3
Goetz TE.The structural and vascular anatomy of the healthy equine foot is compared with the pathologic changes in the foot of horses with acute and chronic laminitis. The structural and vascular abnormalities present in the foot of horses with laminitis are demonstrated in order to explain the abnormal manner in which their feet grow. The medical, surgical, dietary, and endocrine management of acute and chronic laminitis is discussed. Various forms of hoof trimming beneficial to the reestablishment of normal digital perfusion, normal hoof growth, and normal spatial orientation among the distal phalanx...
Ganglioneuroma as a cause of small intestinal obstruction in the horse: a case report.
The Cornell veterinarian    April 1, 1989   Volume 79, Issue 2 133-141 
Allen D, Swayne D, Belknap JK.The clinical signs, medical and surgical management, and pathological findings are described for a ganglioneuroma, an atypical intestinal tumor, that caused colic because of small intestinal obturation.
Management of lacerations and avulsion injuries of the foot and pastern region and hoof wall cracks.
The Veterinary clinics of North America. Equine practice    April 1, 1989   Volume 5, Issue 1 195-220 doi: 10.1016/s0749-0739(17)30611-9
Stashak TS.The causes, clinical signs and various approaches to treatment of injuries involving the foot and pastern regions are reviewed, and the prognosis for each type of injury is discussed.
Tyzzer’s disease in a foal.
Nihon juigaku zasshi. The Japanese journal of veterinary science    April 1, 1989   Volume 51, Issue 2 444-446 doi: 10.1292/jvms1939.51.444
Shirakawa T, Maruyama K, Nakamura N, Awakura T, Ohishi H, Senba H, Higuchi T, Sonoda K, Ono T, Matsui T.No abstract available
[What should the therapy be in a horse with a cough?].
Tijdschrift voor diergeneeskunde    April 1, 1989   Volume 114, Issue 7 397-398 
No abstract available