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Topic:Disease Management

Disease management in horses encompasses the strategies and practices employed to prevent, control, and treat diseases affecting equine populations. This field involves understanding the etiology, transmission, and clinical presentation of various equine diseases, as well as implementing biosecurity measures and therapeutic interventions. Common diseases in horses include equine influenza, strangles, and equine herpesvirus. Effective disease management relies on accurate diagnosis, vaccination protocols, and the use of antimicrobials and other treatments. This page compiles peer-reviewed research studies and scholarly articles that explore the methodologies, challenges, and advancements in managing diseases in equine health.
Complete Genome Sequences of Four African Horse Sickness Virus Strains from a Commercial Tetravalent Live Attenuated Vaccine.
Genome announcements    November 25, 2015   Volume 3, Issue 6 doi: 10.1128/genomeA.01375-15
Guthrie AJ, Coetzee P, Martin DP, Lourens CW, Venter EH, Weyer CT, Joone C, le Grange M, Harper CK, Howell PG, MacLachlan NJ.This is a report of the complete genome sequences of plaque-selected isolates of each of the four virus strains included in a South African commercial tetravalent African horse sickness attenuated live virus vaccine.
Can insecticide-treated netting provide protection for Equids from Culicoides biting midges in the United Kingdom?
Parasites & vectors    November 25, 2015   Volume 8 604 doi: 10.1186/s13071-015-1182-x
Baker T, Carpenter S, Gubbins S, Newton R, Lo Iacono G, Wood J, Harrup LE.Biting midges of the genus Culicoides Latreille, 1809 (Diptera: Ceratopogonidae) cause a significant biting nuisance to equines and are responsible for the biological transmission of African horse sickness virus (AHSV). While currently restricted in distribution to sub-Saharan Africa, AHSV has a history of emergence into southern Europe and causes one of the most lethal diseases of horses and other species of Equidae. In the event of an outbreak of AHSV, the use of insecticide treated nets (ITNs) to screen equine accomodation is recommended by competent authorities including the Office Interna...
Sindbis and Middelburg Old World Alphaviruses Associated with Neurologic Disease in Horses, South Africa.
Emerging infectious diseases    November 20, 2015   Volume 21, Issue 12 2225-2229 doi: 10.3201/eid2112.150132
van Niekerk S, Human S, Williams J, van Wilpe E, Pretorius M, Swanepoel R, Venter M.Old World alphaviruses were identified in 52 of 623 horses with febrile or neurologic disease in South Africa. Five of 8 Sindbis virus infections were mild; 2 of 3 fatal cases involved co-infections. Of 44 Middelburg virus infections, 28 caused neurologic disease; 12 were fatal. Middelburg virus likely has zoonotic potential.
Lack of association between arterial oxygen tensions in horses during exploratory coeliotomy and post-operative incisional complications: A retrospective study.
Veterinary journal (London, England : 1997)    November 10, 2015   Volume 210 24-29 doi: 10.1016/j.tvjl.2015.10.058
Robson K, Cripps P, Bardell D.The aim of this retrospective study was to determine if there was an association between the lowest arterial blood oxygen tensions (PaO2) measured during anaesthesia and post-operative incisional complications in horses. Clinical records of 278 horses undergoing ventral midline coeliotomy from 1 January 2010 to 31 December 2013 were examined. The frequency of incisional complications was 32.0% (n = 89). In a multivariable model, intra-operative arterial blood oxygen tensions (PaO2) were not significantly associated with development of an incisional complication (P = 0.351). Using hyper...
Clarification of equine dental nomenclature.
Anatomical record (Hoboken, N.J. : 2007)    October 30, 2015   Volume 298, Issue 12 1969 doi: 10.1002/ar.23199
Menzies R.No abstract available
The importance of muscarinic receptors in domestic animal diseases and therapy: Current and future perspectives.
Veterinary journal (London, England : 1997)    October 23, 2015   Volume 208 13-21 doi: 10.1016/j.tvjl.2015.10.025
Abraham G.This review provides an overview of the early and current literature including contributions that highlight the parasympathetic cholinergic receptor systems in domestic animal tissues. Muscarinic acetylcholine receptors (mAChRs) belong to the subfamily of G protein-coupled receptors and regulate many fundamental functions of the central and peripheral nervous systems and have been subject to research over at least 40 years. Nonetheless, there are few studies specifying mAChRs in domestic animal tissues. This review focuses on the pharmacology of muscarinic acetylcholine receptor (mAChR) system...
Application of economics to equine health and welfare.
Equine veterinary journal    October 18, 2015   Volume 47, Issue 6 633-634 doi: 10.1111/evj.12510
Rushton J, Redmond EF.No abstract available
Antimicrobial use and antimicrobial resistance in horses.
Equine veterinary journal    October 18, 2015   Volume 47, Issue 6 747-749 doi: 10.1111/evj.12469
Weese JS.No abstract available
Surgical site infections: What do we know?
Equine veterinary journal    October 18, 2015   Volume 47, Issue 6 753-755 doi: 10.1111/evj.12480
Verwilghen D.No abstract available
Antimicrobial resistance, equine practitioners and human health: A true One Health issue or political interference?
Equine veterinary journal    October 18, 2015   Volume 47, Issue 6 750-752 doi: 10.1111/evj.12485
Slater JD.No abstract available
Antimicrobial resistance in the horse – EVJ’s online collection.
Equine veterinary journal    October 18, 2015   Volume 47, Issue 6 745-746 doi: 10.1111/evj.12495
Bowen IM, Clegg PD.No abstract available
Bayesian Geostatistical Analysis and Ecoclimatic Determinants of Corynebacterium pseudotuberculosis Infection among Horses.
PloS one    October 16, 2015   Volume 10, Issue 10 e0140666 doi: 10.1371/journal.pone.0140666
Boysen C, Davis EG, Beard LA, Lubbers BV, Raghavan RK.Kansas witnessed an unprecedented outbreak in Corynebacterium pseudotuberculosis infection among horses, a disease commonly referred to as pigeon fever during fall 2012. Bayesian geostatistical models were developed to identify key environmental and climatic risk factors associated with C. pseudotuberculosis infection in horses. Positive infection status among horses (cases) was determined by positive test results for characteristic abscess formation, positive bacterial culture on purulent material obtained from a lanced abscess (n = 82), or positive serologic evidence of exposure to organism ...
Routes of Hendra Virus Excretion in Naturally-Infected Flying-Foxes: Implications for Viral Transmission and Spillover Risk.
PloS one    October 15, 2015   Volume 10, Issue 10 e0140670 doi: 10.1371/journal.pone.0140670
Edson D, Field H, McMichael L, Vidgen M, Goldspink L, Broos A, Melville D, Kristoffersen J, de Jong C, McLaughlin A, Davis R, Kung N, Jordan D....Pteropid bats or flying-foxes (Chiroptera: Pteropodidae) are the natural host of Hendra virus (HeV) which sporadically causes fatal disease in horses and humans in eastern Australia. While there is strong evidence that urine is an important infectious medium that likely drives bat to bat transmission and bat to horse transmission, there is uncertainty about the relative importance of alternative routes of excretion such as nasal and oral secretions, and faeces. Identifying the potential routes of HeV excretion in flying-foxes is important to effectively mitigate equine exposure risk at the bat...
Tackling ‘the four horsemen of the equine anaesthetic apocalypse’.
The Veterinary record    October 10, 2015   Volume 177, Issue 14 357-359 doi: 10.1136/vr.h5326
Harris G.No abstract available
Practical management of strangles outbreaks in horses.
Australian veterinary journal    October 7, 2015   Volume 93, Issue 8 N20 
Richmond R.No abstract available
Prospective study of the primary evaluation of 1016 horses with clinical signs of abdominal pain by veterinary practitioners, and the differentiation of critical and non-critical cases.
Acta veterinaria Scandinavica    October 6, 2015   Volume 57 69 doi: 10.1186/s13028-015-0160-9
Curtis L, Burford JH, Thomas JS, Curran ML, Bayes TC, England GC, Freeman SL.The majority of research on the evaluation of horses with colic is focused on referral hospital populations. Early identification of critical cases is important to optimise outcome and welfare. The aim of this prospective study was to survey the primary evaluation of horses with clinical signs of abdominal pain by veterinary practitioners, and compare the initial presentation of critical and non-critical cases. Results: Data from 1016 primary evaluations of horses presenting with clinical signs of colic were submitted by 167 veterinary practitioners across the United Kingdom over a 13 month p...
Effect of emptying the vasculature before performing regional limb perfusion with amikacin in horses.
Equine veterinary journal    October 6, 2015   Volume 48, Issue 6 737-740 doi: 10.1111/evj.12501
Sole A, Nieto JE, Aristizabal FA, Snyder JR.Emptying the vasculature with an Esmarch bandage before i.v. regional anaesthesia is commonly performed in human patients to prevent leakage of the solution under the tourniquet but there is no evidence for its efficacy in horses for antimicrobial i.v. regional limb perfusion (IV-RLP). Objective: To determine the effect on synovial fluid concentration of amikacin of emptying the vasculature before performing IV-RLP. Methods: Crossover experiment. Methods: Eight clinically healthy horses underwent 2 IV-RLP with amikacin in a randomised, crossover design. Horses received an IV-RLP with amikacin ...
Efficacy of major anthelmintics for reduction of fecal shedding of strongyle-type eggs in horses in the Mid-Atlantic region of the United States.
Veterinary parasitology    September 30, 2015   Volume 214, Issue 1-2 139-143 doi: 10.1016/j.vetpar.2015.09.025
Smith MA, Nolan TJ, Rieger R, Aceto H, Levine DG, Nolen-Walston R, Smith BI.In the last decade there have been numerous reports of anthelmintic resistant cyathostomins in many parts of the world. The objective of the present study was to evaluate the efficacy of the commercially available anthelmintics against cyathostomin egg shedding in the Mid-Atlantic region of the United States. A total of 989 horses from 67 different farms located in southeastern Pennsylvania, northern Delaware, and northeastern Maryland were treated with fenbendazole, oxibendazole, pyrantel pamoate, ivermectin, or moxidectin at their recommended dosages. Fecal egg count reduction testing was us...
Evaluation of serum amyloid A and haptoglobin concentrations as prognostic indicators for horses with inflammatory disease examined at a tertiary care hospital.
American journal of veterinary research    September 29, 2015   Volume 76, Issue 10 882-888 doi: 10.2460/ajvr.76.10.882
Westerman TL, Tornquist SJ, Foster CM, Poulsen KP.To evaluate use of serum amyloid A (SAA) and haptoglobin concentrations as prognostic indicators for horses with inflammatory disease in regard to euthanasia, complications, and hospitalization duration and cost. Methods: 20 clinically normal horses and 53 horses with inflammatory disease. Methods: Total WBC count, neutrophil count, and fibrinogen, SAA, and haptoglobin concentrations were determined for clinically normal horses and horses with suspected inflammatory disease. Clinicopathologic values at admission were compared to test the use of SAA and haptoglobin concentrations in predicting ...
A systematic review and meta-analysis of animal-type melanoma.
Journal of the American Academy of Dermatology    September 26, 2015   Volume 73, Issue 6 1031-1039 doi: 10.1016/j.jaad.2015.08.016
Vyas R, Keller JJ, Honda K, Cooper KD, Gerstenblith MR.Animal-type melanoma is a rare subtype of melanoma with heavily pigmented dermal epithelioid and spindled melanocytes. Its classification as a subtype of melanoma versus a borderline melanocytic tumor is debated. Objective: Our primary objective was to characterize the demographics, clinical presentation, histopathology, management, and outcomes of patients with animal-type melanoma. Methods: We performed a systematic review and meta-analysis of the English-language literature on animal-type melanoma. Results: We identified 190 cases of animal-type melanoma. They occurred equally in men and wo...
Clinical Research Abstracts of the British Equine Veterinary Association Congress 2015.
Equine veterinary journal    September 17, 2015   Volume 47 Suppl 48 28 doi: 10.1111/evj.12486_63
Lotstra RJ, van den Broek J, Power T, Marr CM, Wijnberg ID.Atrial fibrillation is a common equine arrhythmia. Quinidine alone, or with digoxin are common treatments. Studies on outcome in Warmblood populations in which duration of the AF is often unknown are limited. Objective: To identify the factors that are associated with the success of full treatment cardioversion with oral medication, and establish whether there are differences in these factors between institutions. Methods: Retrospective case series using patient records of Equine University Clinic of Utrecht University and Rossdales Equine Hospital, Newmarket. Methods: Forty-nine horses treate...
Clinical Research Abstracts of the British Equine Veterinary Association Congress 2015.
Equine veterinary journal    September 17, 2015   Volume 47 Suppl 48 16 doi: 10.1111/evj.12486_36
Hardeman LC, van der Meij BR, Back W, van der Kolk JH, Wijnberg ID.In cases of laminitis, an increased muscle force or contracture of the deep digital flexor muscle (DDFM) is suggested, but evidence-based research is lacking. Objective: To test if the DDFM of laminitic equines shows an increased muscle force detectable by needle-EMG including Interference Pattern Analysis (IPA). Methods: Cross-sectional study. Methods: Three groups consisted of Group 0 (control): 6 Royal Dutch Sport horses, 3 Shetland ponies and one Welsh pony (healthy, sound adults, mean ± s.d. weight 411 ± 217 kg). Group 1: 3 Royal Dutch Sport horses, one Friesian, one Haflinger...
Clinical Research Abstracts of the British Equine Veterinary Association Congress 2015.
Equine veterinary journal    September 17, 2015   Volume 47 Suppl 48 28 doi: 10.1111/evj.12486_63
Lotstra RJ, van den Broek J, Power T, Marr CM, Wijnberg ID.Atrial fibrillation is a common equine arrhythmia. Quinidine alone, or with digoxin are common treatments. Studies on outcome in Warmblood populations in which duration of the AF is often unknown are limited. Objective: To identify the factors that are associated with the success of full treatment cardioversion with oral medication, and establish whether there are differences in these factors between institutions. Methods: Retrospective case series using patient records of Equine University Clinic of Utrecht University and Rossdales Equine Hospital, Newmarket. Methods: Forty-nine horses treate...
Hypoglycin A Content in Blood and Urine Discriminates Horses with Atypical Myopathy from Clinically Normal Horses Grazing on the Same Pasture.
PloS one    September 17, 2015   Volume 10, Issue 9 e0136785 doi: 10.1371/journal.pone.0136785
Bochnia M, Ziegler J, Sander J, Uhlig A, Schaefer S, Vollstedt S, Glatter M, Abel S, Recknagel S, Schusser GF, Wensch-Dorendorf M, Zeyner A.Hypoglycin A (HGA) in seeds of Acer spp. is suspected to cause seasonal pasture myopathy in North America and equine atypical myopathy (AM) in Europe, fatal diseases in horses on pasture. In previous studies, this suspicion was substantiated by the correlation of seed HGA content with the concentrations of toxic metabolites in urine and serum (MCPA-conjugates) of affected horses. However, seed sampling was conducted after rather than during an outbreak of the disease. The aim of this study was to further confirm the causality between HGA occurrence and disease outbreak by seed sampling during ...
A survey on parasite management by equine veterinarians highlights the need for a regulation change.
Veterinary record open    September 14, 2015   Volume 2, Issue 2 e000104 doi: 10.1136/vetreco-2014-000104
Sallé G, Cabaret J.In-depth knowledge of the use of anthelminthics in the field, especially by veterinarians, is required to design more sustainable parasite control strategies. Methods: An online survey was sent by e-mail to 940 equine veterinary practitioners to describe their equine practice, their awareness about parasites and the management strategies they apply. Results: Gastrointestinal parasites were generally considered (68%) as an issue of moderate importance. Drug efficacy failure was a minor or moderate issue for 47% and 48% of responders, respectively. Parasite management mostly relied on the use of...
Biphasic appearance of corticated and decorticated ascarid egg shedding in untreated horse foals.
Veterinary parasitology    September 11, 2015   Volume 214, Issue 1-2 114-117 doi: 10.1016/j.vetpar.2015.09.003
Donoghue EM, Lyons ET, Bellaw JL, Nielsen MK.Parascaris spp. infects foals worldwide and may cause airway inflammation in addition to small intestinal impaction and rupture. It is observed that acquired immunity eliminates ascarid burdens beginning at about 6 months of age, and current evidence suggests that a single parasite generation propagates in each foal crop. The purpose of this study was to monitor natural parasitic infections in untreated mixed breed horse foals over the course of 0-300 days of age. Fecal samples were collected monthly from all foals born in 2014 (n=13), beginning July 2014 through February 2015. Fecal egg count...
European College of Equine Internal Medicine Consensus Statement–Equine Gastric Ulcer Syndrome in Adult Horses.
Journal of veterinary internal medicine    September 5, 2015   Volume 29, Issue 5 1288-1299 doi: 10.1111/jvim.13578
Sykes BW, Hewetson M, Hepburn RJ, Luthersson N, Tamzali Y.No abstract available
Prepare for atypical myopathy, says BEVA.
The Veterinary record    September 5, 2015   Volume 177, Issue 9 217 doi: 10.1136/vr.h4683
No abstract available
Suspected ivermectin resistance in a south-east Queensland Parascaris equorum population.
Australian veterinary journal    August 28, 2015   Volume 93, Issue 9 305-307 doi: 10.1111/avj.12352
Beasley A, Coleman G, Kotze AC.There have been several international reports of macrocyclic lactone (ML)-resistant Parascaris equorum over the past decade, but the resistance status of Australian P. equorum populations is largely unknown. A case of apparent reduced efficacy of ivermectin against P. equorum in Australia was investigated. Results: A faecal egg count reduction test carried out on a group of weanling foals in south-east Queensland showed the efficacy of ivermectin to be 65%. Conclusions: The case highlights the need to review current worm control strategies, especially for young horses.
Aspergillus and aspergilloses in wild and domestic animals: a global health concern with parallels to human disease.
Medical mycology    August 26, 2015   Volume 53, Issue 8 765-797 doi: 10.1093/mmy/myv067
Seyedmousavi S, Guillot J, Arné P, de Hoog GS, Mouton JW, Melchers WJ, Verweij PE.The importance of aspergillosis in humans and various animal species has increased over the last decades. Aspergillus species are found worldwide in humans and in almost all domestic animals and birds as well as in many wild species, causing a wide range of diseases from localized infections to fatal disseminated diseases, as well as allergic responses to inhaled conidia. Some prevalent forms of animal aspergillosis are invasive fatal infections in sea fan corals, stonebrood mummification in honey bees, pulmonary and air sac infection in birds, mycotic abortion and mammary gland infections in ...
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