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Topic:Disease Surveillance

Disease surveillance in horses involves the systematic collection, analysis, and interpretation of health data to monitor and manage equine diseases. This process aids in the early detection of outbreaks, tracking of disease trends, and evaluation of control measures. Surveillance systems may incorporate various data sources, including clinical reports, laboratory testing, and field observations. These systems can focus on infectious diseases, such as equine influenza and West Nile virus, or non-infectious conditions affecting horse populations. This page compiles peer-reviewed research studies and scholarly articles that explore methodologies, technologies, and outcomes associated with disease surveillance in equine populations.
Success and Limitation of Equine Influenza Vaccination: The First Incursion in a Decade of a Florida Clade 1 Equine Influenza Virus that Shakes Protection Despite High Vaccine Coverage.
Vaccines    November 2, 2019   Volume 7, Issue 4 174 doi: 10.3390/vaccines7040174
Fougerolle S, Fortier C, Legrand L, Jourdan M, Marcillaud-Pitel C, Pronost S, Paillot R.Every year, several epizooties of equine influenza (EI) are reported worldwide. However, no EI case has been identified in France between 2015 and late 2018, despite an effective field surveillance of the pathogen and the disease. Vaccination against equine influenza virus (EIV) remains to this day one of the most effective methods to prevent or limit EI outbreaks and the lack of detection of the pathogen could be linked to vaccination coverage. The aim of this study was to evaluate EI immunity and vaccine coverage in France through a large-scale serological study. A total of 3004 archived sur...
Epidemiological Study of Equine Piroplasmosis (Theileria equi and Babesia caballi) by Microscopic Examination and Competitive-ELISA in Erbil Province North-Iraq.
Iranian journal of parasitology    November 2, 2019   Volume 14, Issue 3 404-412 
Aziz KJ, Al-Barwary LTO.Equine piroplasmosis is a major tick-borne disease that can lead to serious health problems and economic losses in horse industry. The aim of the study is to determine the prevalence of and in different species of Equus namely (Horse, mule, donkey and pony) by Giemsa stained blood films and competitive ELISA. Methods: This study was conducted at various geographic areas of Erbil governorate. A total of 349 blood samples from equine (209 horses, 62 mule, 57 donkey and 21 ponies) were collected to estimate the prevalence rate of and by using Giemsa stained blood smear and competitive ELISA. ...
Clinical Evaluation and Preventative Care in Donkeys.
The Veterinary clinics of North America. Equine practice    November 2, 2019   Volume 35, Issue 3 545-560 doi: 10.1016/j.cveq.2019.08.013
Barrio E, Rickards KJ, Thiemann AK.Clinical evaluation and preventative care in donkeys should follow similar guidelines as for horses. There are species-specific differences due to the desert-adapted physiology of the donkey. Donkeys are mainly used as pack animals, companions and for production of meat or milk - they may be kept well into old age. Diseases often present late or may go unrecognized leading to poor welfare and quality of life. Basic knowledge of nutrition, blood values, pharmacology and common disease recognition will help veterinarians improve the health and welfare of donkeys.
African horse sickness: a potential threat to the UK.
The Veterinary record    October 28, 2019   Volume 185, Issue 16 501-503 doi: 10.1136/vr.l6189
The UK has never experienced an outbreak of African horse sickness but, as Matthew Robin of the Fyrnwy Equine Clinic explains, there is still a risk of a case occurring.
Molecular investigation and phylogeny of species of the Anaplasmataceae infecting animals and ticks in Senegal.
Parasites & vectors    October 22, 2019   Volume 12, Issue 1 495 doi: 10.1186/s13071-019-3742-y
Dahmani M, Davoust B, Sambou M, Bassene H, Scandola P, Ameur T, Raoult D, Fenollar F, Mediannikov O.Our study aimed to assess the diversity of the species of Anaplasmataceae in Senegal that infect animals and ticks in three areas: near Keur Momar Sarr (northern region), Dielmo and Diop (Sine Saloum, central region of Senegal), and in Casamance (southern region of Senegal). Methods: A total of 204 ticks and 433 blood samples were collected from ruminants, horses, donkeys and dogs. Ticks were identified morphologically and by molecular characterization targeting the 12S rRNA gene. Molecular characterization of species of Anaplasmataceae infecting Senegalese ticks and animals was conducted usin...
Seroprevalence of Toxoplasma gondii in horses: A global systematic review and meta-analysis.
Acta tropica    October 19, 2019   Volume 201 105222 doi: 10.1016/j.actatropica.2019.105222
Li X, Ni HB, Ren WX, Jiang J, Gong QL, Zhang XX.Toxoplasmosis, one of the most common zoonoses worldwide, is caused by Toxoplasma gondii. T. gondii can infect almost all warm-blooded animals, including humans. Horses are an intermediate host of T. gondii, representing a potential risk for humans. To determine the T. gondii seroprevalence in horses worldwide, a global meta-analysis was conducted. A total of 35 publications were obtained by searching the PubMed, ScienceDirect, Chinese Web of knowledge (CNKI) and Wanfang databases. A total of 12,354 horses were assessed, of which 1580 were positive for T. gondii. The pooled overall seroprevale...
Piroplasmosis in Italian Standardbred Horses: 15 Years of Surveillance Data.
Journal of equine veterinary science    October 18, 2019   Volume 83 102813 doi: 10.1016/j.jevs.2019.102813
Padalino B, Rosanowski SM, Di Bella C, Lacinio R, Rubino GTR.This study aimed to document the prevalence of chronic equine piroplasmosis (EP) in poorly performing Standardbred racehorses and to explore associations between the disease and sex, age, and hematological parameters. Blood was collected between 2004 and 2018; blood cell counts were performed using a cell counter analyzer, biochemical parameters using a photometer, and serum proteins using agarose gel electrophoresis. Blood smears were prepared, colored with a modified Giemsa, and an experienced technician identified the presence of protozoa. The horses were categorized into piroplasmosis posi...
Horses for courses: an approach to the qualification of clinical trial sites and investigators in ATMPs.
Drug discovery today    October 16, 2019   Volume 25, Issue 2 265-268 doi: 10.1016/j.drudis.2019.10.003
Hildebrandt M.The advanced therapy medicinal products (ATMPs) landscape is entirely different from classical drug development. Academia has been the major source of ATMP development, and academic hospitals act as trial sites for the clinical testing of ATMPs, including early academic-led trials as well as industry-sponsored trials that pursue the full developmental pathway to market authorization. The recent breakthrough developments in some ATMPs, such as genetically engineered immune cells, have confronted academic hospitals with a substantial amount of public demand, competitive pressure, and costs. At t...
Leishmania spp. and leishmaniasis on the Caribbean islands.
Transactions of the Royal Society of Tropical Medicine and Hygiene    October 15, 2019   Volume 114, Issue 2 73-78 doi: 10.1093/trstmh/trz076
Yao C.The kinetoplastid protozoan Leishmania spp. cause leishmaniasis, which clinically exhibit mainly as a cutaneous, mucocutanous or visceral form depending upon the parasite species in humans. The disease is widespread geographically, leading to 20 000 annual deaths. Here, leishmaniases in both humans and animals, reservoirs and sand fly vectors on the Caribbean islands are reviewed. Autochthonous human infections by Leishmania spp. were found in the Dominican Republic, Guadeloupe and Martinique as well as Trinidad and Tobago; canine infections were found in St. Kitts and Grenada; and equine infe...
Preliminary insight into horse owners’ perceptions of, and attitudes towards, exotic diseases in the United Kingdom.
BMC veterinary research    October 12, 2019   Volume 15, Issue 1 338 doi: 10.1186/s12917-019-2120-5
Spence KL, Cardwell JM, Slater J, Rosanowski SM.The potential for an exotic disease incursion is a significant concern for the United Kingdom (UK) equine industry. Horse owners' perceptions of, and attitudes towards, exotic diseases can influence decisions to adopt disease preparedness strategies. The objectives of this study were to describe horse owners' 1) perceptions of the term 'exotic disease', and 2) attitudes towards their risk of being affected by an exotic disease. In order to address these objectives, qualitative content analysis was undertaken on data collected using two open-ended survey questions. Results: Horse owners (n =â€...
Co-resistance to Amoxicillin and Tetracycline as an Indicator of Multidrug Resistance in Escherichia coli Isolates From Animals.
Frontiers in microbiology    October 9, 2019   Volume 10 2288 doi: 10.3389/fmicb.2019.02288
Bourély C, Cazeau G, Jarrige N, Jouy E, Haenni M, Lupo A, Madec JY, Leblond A, Gay E.To examine the relevance of co-resistance to amoxicillin and tetracycline as an indicator of multidrug resistance (MDR) in animal health. Methods: isolates collected between 2012 and 2016 by the French surveillance network for antimicrobial resistance in diseased animals (RESAPATH) were analyzed. The proportions of MDR isolates and the proportions of isolates presenting co-resistance to amoxicillin and tetracycline were calculated for seven animal species (cattle, horse, dog, swine, poultry, duck, and turkey). The degree of agreement between these two proportions was estimated by calculating ...
Molecular Surveillance of EHV-1 Strains Circulating in France during and after the Major 2009 Outbreak in Normandy Involving Respiratory Infection, Neurological Disorder, and Abortion.
Viruses    October 4, 2019   Volume 11, Issue 10 916 doi: 10.3390/v11100916
Sutton G, Garvey M, Cullinane A, Jourdan M, Fortier C, Moreau P, Foursin M, Gryspeerdt A, Maisonnier V, Marcillaud-Pitel C, Legrand L, Paillot R....Equine herpesvirus 1 (EHV-1) is an Alphaherpesvirus infecting not only horses but also other equid and non-equid mammals. It can cause respiratory distress, stillbirth and neonatal death, abortion, and neurological disease. The different forms of disease induced by EHV-1 infection can have dramatic consequences on the equine industry, and thus the virus represents a great challenge for the equine and scientific community. This report describes the progress of a major EHV-1 outbreak that took place in Normandy in 2009, during which the three forms of disease were observed. A collection of EHV-1...
Respiratory Disorders of the Donkey.
The Veterinary clinics of North America. Equine practice    October 3, 2019   Volume 35, Issue 3 561-573 doi: 10.1016/j.cveq.2019.08.009
Rickards KJ, Thiemann AK.Donkeys suffer from the same respiratory diseases as horses; however, owing to their nonathletic nature many conditions can present in a more advanced state before becoming clinically apparent. Anatomically, their respiratory tract is similar to the horse, with certain species-specific differences that are important to be aware of. Often donkeys do not receive the same level of routine care as horses, so many are not vaccinated against respiratory pathogens such as influenza or herpesviruses. Donkeys can act as a reservoir for certain infectious and parasitic respiratory diseases and the inter...
West Nile fever in Europe in 2018: an emerging problem or just an anomaly?
The Veterinary record    September 29, 2019   Volume 185, Issue 12 365-368 doi: 10.1136/vr.l5748
Browne C, Medlock JM.Last summer saw an unusually high number of cases of West Nile fever in horses and people in south and south-east Europe, but it is too early to tell if this was a one-off increase or a sign of things to come. Here, , , and discuss the various West Nile fever surveillance and control mechanisms in place in the UK.
A study regarding bovine enterovirus type 1 infection in domestic animals and humans: An evaluation from the zoonotic aspect.
The Journal of veterinary medical science    September 27, 2019   Volume 81, Issue 12 1824-1828 doi: 10.1292/jvms.18-0704
Gür S, Gürçay M, Seyrek A.Bovine enteroviruses (BEV) are members of Enterovirus genus of the family Picornaviridae. BEV1 has a broad host spectrum, including humans. The virus usually causes subclinical infection, but fatal/severe cases have also been reported in different animal species. There is quite limited data regarding BEV1 in humans. The purpose of this study is to investigate human infection and to identify possible risk factors for viral exposure. For this purpose, blood serum samples (n=1,526) were collected from a city center and nearby villagers simultaneously from humans and farm animals in Elazig provinc...
Letter to the Editor: Response to letter regarding: Prospective, randomised clinical trial of four different presurgical hand antiseptic techniques in equine surgery.
Equine veterinary journal    September 25, 2019   Volume 52, Issue 1 158-159 doi: 10.1111/evj.13167
Biermann NM, McClure JT, Doyle AJ.No abstract available
Molecular identification of vector-borne organisms in Ehrlichia seropositive Nicaraguan horses and first report of Rickettsia felis infection in the horse.
Acta tropica    September 10, 2019   Volume 200 105170 doi: 10.1016/j.actatropica.2019.105170
Tyrrell JD, Qurollo BA, Tornquist SJ, Schlaich KG, Kelsey J, Chandrashekar R, Breitschwerdt EB.Certain vector-borne organisms serve as etiological agents of equine disease. After previously identifying a new Ehrlichia species in horses from Mérida, we aimed to determine the infection frequency and screen for a wide range of vector-borne organisms from 93 tick-exposed, Ehrlichia seropositive horses in this region. PCR assays were performed to identify infection by organisms within the following genera: Anaplasma, Babesia, Bartonella, Ehrlichia, Leishmania, Mycoplasma, Neorickettsia, Rickettsia and Theileria. Overall, 90/93 horses (96.8%) were infected with one or more vector-borne organ...
Estimation of the incidence of animal rabies in Punjab, India.
PloS one    September 9, 2019   Volume 14, Issue 9 e0222198 doi: 10.1371/journal.pone.0222198
Gill GS, Singh BB, Dhand NK, Aulakh RS, Sandhu BS, Ward MP, Brookes VJ.Rabies is a devastating zoonotic disease of mammals that causes encephalitis and death. It is endemic in India, with an estimated annual 20,000 human deaths (one-third of the global rabies burden). The magnitude of animal rabies incidence is unknown. In four sub-districts of Punjab, India, we monitored canine and livestock populations from August 15, 2016 to August 14, 2017. Demographic, clinical and rabies diagnostic laboratory (RDL) data were collected from suspected cases of rabies. The annual incidence rate / 10,000 animal years at risk (95% CI) in each sub-district was estimated for each ...
Genetic characteristics of Theileria equi in zebras, wild and domestic donkeys in Israel and the Palestinian Authority.
Ticks and tick-borne diseases    September 4, 2019   Volume 11, Issue 1 101286 doi: 10.1016/j.ttbdis.2019.101286
Tirosh-Levy S, Gottlieb Y, Arieli O, Mazuz ML, King R, Horowitz I, Steinman A.Equine piroplasmosis (EP) is an important tick-borne disease of equids, caused by Theileria equi and Babesia caballi. It is endemic in most parts of the world, including Israel, and has clinical and economic consequences. This study was set to evaluate the presence of EP parasites in domestic donkeys and in wild equids in Israel and the Palestinian Authority (PA). To assess subclinical EP infection in 98 domestic donkeys (Equus africanus asinus), 9 Asiatic wild donkeys (Equus hemionus), 8 zebras (Equus quagga), 7 African wild donkeys (Equus africanus) and 5 mules, were tested using PCR and qPC...
Approach to Strain Selection and the Propagation of Viral Stocks for Venezuelan Equine Encephalitis Virus Vaccine Efficacy Testing under the Animal Rule.
Viruses    August 31, 2019   Volume 11, Issue 9 807 doi: 10.3390/v11090807
Rusnak JM, Glass PJ, Weaver SC, Sabourin CL, Glenn AM, Klimstra W, Badorrek CS, Nasar F, Ward LA.Licensure of a vaccine to protect against aerosolized Venezuelan equine encephalitis virus (VEEV) requires use of the U.S. Food and Drug Administration (FDA) Animal Rule to assess vaccine efficacy as human studies are not feasible or ethical. An approach to selecting VEEV challenge strains for use under the Animal Rule was developed, taking into account Department of Defense (DOD) vaccine requirements, FDA Animal Rule guidelines, strain availability, and lessons learned from the generation of filovirus challenge agents within the Filovirus Animal Nonclinical Group (FANG). Initial down-selectio...
Equine viral arteritis in the UK.
The Veterinary record    August 24, 2019   Volume 185, Issue 8 234 doi: 10.1136/vr.l5211
Cooke G.No abstract available
Characterization of the viral genomes present in commercial batches of horse serum obtained by high-throughput sequencing.
Biologicals : journal of the International Association of Biological Standardization    August 23, 2019   Volume 61 1-7 doi: 10.1016/j.biologicals.2019.08.005
Paim WP, Weber MN, Cibulski SP, da Silva MS, Puhl DE, Budaszewski RF, Varela APM, Mayer FQ, Canal CW.Horses are often used as blood donors for commercial horse serum (HS) production and to manufacture biologicals. HS is an alternative for fetal bovine serum (FBS) used as a supplement for cell culture and vaccine production. Furthermore, HS is also frequently obtained in order to produce antisera toxins and pathogens. The advent of high-throughput sequencing (HTS) has promoted changes in virus detection, since previous knowledge of targets is not required. Thus, the present study aimed to describe the virome of five different batches of commercial HS from New Zealand (three batches) and Brazil...
Molecular characterization of Equine Infectious Anemia Viruses using targeted sequence enrichment and next generation sequencing.
Virology    August 22, 2019   Volume 537 121-129 doi: 10.1016/j.virol.2019.08.016
Deshiere A, Berthet N, Lecouturier F, Gaudaire D, Hans A.Equine infectious anemia virus (EIAV) is responsible of acute disease episodes characterized by fever, anemia, thrombocytopenia and anorexia in equids. The high mutation rate in EIAV genome limited the number of full genome sequences availability. In the present study, we used the SureSelect target enrichment system with Illumina Next Generation Sequencing to characterize the proviral DNA of Equine Infectious Anemia Virus (EIAV) from asymptomatic horses. This approach allows a direct sequencing of the EIAV whole genome without cloning or amplification steps and we could obtain for the first ti...
The importance of anthelmintic efficacy monitoring: results of an outreach effort.
Parasitology research    August 17, 2019   Volume 118, Issue 10 2877-2883 doi: 10.1007/s00436-019-06423-6
Cain JL, Foulk D, Jedrzejewski E, Stofanak H, Nielsen MK.Anthelmintic resistance in equine cyathostomin parasites is widespread. A surveillance-based parasite control program using fecal egg counts (FECs) and fecal egg count reduction tests (FECRTs) to decrease anthelmintic use and monitor treatment efficacy is recommended. The purpose of this study was to examine shifts in equine parasite control program management practices via a short course presented by the Penn State Extension, and to highlight how data collected from these programs is useful for monitoring anthelmintic efficacy on a large scale. Horse owners were enrolled after participating i...
A Seroepidemiological Survey of Theileria equi and Babesia caballi in Horses in Mongolia.
The Journal of parasitology    August 16, 2019   Volume 105, Issue 4 580-586 
Myagmarsuren P, Sivakumar T, Enkhtaivan B, Davaasuren B, Zoljargal M, Narantsatsral S, Davkharbayar B, Mungun-Ochir B, Battur B, Inoue N, Igarashi I....Equine piroplasmosis caused by and is an economically important disease with a worldwide distribution. The objective of the present study was to investigate the seroepidemiology of and in horses reared in various Mongolian provinces. Serum samples prepared from blood collected from horses in 19 Mongolian provinces were screened for antibodies specific to and using enzyme-linked immunosorbent assays based on recombinant forms of merozoite antigen-2 and the 48-kDa merozoite rhoptry protein, respectively. Of 1,282 horses analyzed, 423 (33%) and 182 (14.2%) were sero-positive for and , re...
Temporal efficacy of antimicrobials against aerobic bacteria isolated from equine endometritis: an Italian retrospective analysis (2010-2017).
The Veterinary record    August 13, 2019   Volume 185, Issue 19 598 doi: 10.1136/vr.105413
Pisello L, Rampacci E, Stefanetti V, Beccati F, Hyatt DR, Coletti M, Passamonti F.This study aimed to describe bacteria isolated from the reproductive tract of mares and to identify changes in antimicrobial susceptibility patterns to those antibiotics commonly used for the treatment of equine endometritis. A total of 4122 equine uterine swabs were collected from mares suffering from reproductive tract disorders in the period 2010-2017. Aerobic culture and antimicrobial susceptibility testing using agar disc diffusion were performed on each sample. Aerobic bacteria were isolated from 3171 of 4122 (76.9 per cent) samples. The most frequently isolated microorganisms were (885...
Equine viral encephalitis: prevalence, impact, and management strategies.
Veterinary medicine (Auckland, N.Z.)    August 7, 2019   Volume 10 99-110 doi: 10.2147/VMRR.S168227
Barba M, Fairbanks EL, Daly JM.Members of several different virus families cause equine viral encephalitis, the majority of which are arthropod-borne viruses (arboviruses) with zoonotic potential. The clinical signs caused are rarely pathognomonic; therefore, a clinical diagnosis is usually presumptive according to the geographical region. However, recent decades have seen expansion of the geographical range and emergence in new regions of numerous viral diseases. In this context, this review presents an overview of the prevalence and distribution of the main viral causes of equine encephalitis and discusses their impact an...
Molecular characterization of equine infectious anaemia virus strains detected in England in 2010 and 2012.
Transboundary and emerging diseases    August 7, 2019   Volume 66, Issue 6 2311-2317 doi: 10.1111/tbed.13286
Dorey-Robinson DLW, Locker N, Steinbach F, Choudhury B.Equine infectious anaemia virus (EIAV) is a retrovirus with worldwide distribution which is notifiable to the OIE. Despite its importance to the equine industry, most information regarding its biology have been obtained using only two strains (EIAV and EIAV ) from the USA and China, respectively. Recently full genome sequences from Ireland, Italy and Japan have been published; however, this is still not representative of the number of EIAV outbreaks experienced globally each year. The limited availability of published sequences makes design of a universal EIAV PCR difficult, hence diagnosis is...
Report of the Fourth International Havemeyer Workshop on Equid Herpesviruses (EHV) EHV-1, EHV-2 and EHV-5.
Equine veterinary journal    August 3, 2019   Volume 51, Issue 5 565-568 doi: 10.1111/evj.13141
Kydd JH, Lunn DP, Osterrieder K.No abstract available
Highlights of recent clinically relevant papers.
Equine veterinary education    August 1, 2019   Volume 31, Issue 9 450-451 doi: 10.1111/eve.13155
Wright S.No abstract available
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