Disease surveillance in horses involves the systematic collection, analysis, and interpretation of health data to monitor and manage equine diseases. This process aids in the early detection of outbreaks, tracking of disease trends, and evaluation of control measures. Surveillance systems may incorporate various data sources, including clinical reports, laboratory testing, and field observations. These systems can focus on infectious diseases, such as equine influenza and West Nile virus, or non-infectious conditions affecting horse populations. This page compiles peer-reviewed research studies and scholarly articles that explore methodologies, technologies, and outcomes associated with disease surveillance in equine populations.
Desmettre P.The frequent transfers of horses, whether on a permanent or temporary basis, make strict control of infectious diseases essential. Such control needs a reliable and rapid means to accurately diagnose the relevant diseases. Indirect diagnosis based on antibody detection remains certainly the best method to secure the epidemiologic surveillance of the diseases at regional, national, or even world level, while direct diagnosis is the only way to diagnose a new outbreak. New diagnostic methods resulting from advances in biochemistry, molecular biology, and immunology are now available. As far as a...
Reyna-Bello A, GarcÃa FA, Rivera M, Sansó B, Aso PM.The standardization of ELISA for the detection of anti-Trypanosoma evansi antibodies in naturally and experimentally infected horses is described. Bayesian analysis was used to establish the cutoff between positive and negative sera. In order to determine the assessment of the ELISA test, the results obtained were compared with those from an IFA. A relative sensibility of 98.39%, a specificity of 95.12% and a predictive value of 96.83% were determined. The standardized technique was used to evaluate the antibody production against trypanosome in an experimentally infected equine, in which the ...
al-Afaleq AI, Abu Elzein EM, Hassanein MM.The present epidemiological status of African horse sickness in Saudi Arabia, as shown by seroconversion, virus isolation and clinical observation of sentinel horses is described. No African horse sickness virus activity was detected throughout the duration of the study (from November 1992 to March 1995). These findings support previous reports that African horse sickness is not endemic in Saudi Arabia.
Rocha T.This paper presents a review of Leptospira infection in farm animals in Portugal which is based mainly on serological results obtained in the National Veterinary Research Laboratory between January 1987 and December 1993. Serum samples were tested by the microscopic agglutination test, at a minimum dilution of 1:100. Positive titres were obtained in 15.3% of the 9,543 bovine samples examined. Sejroe, Pomona, Hebdomadis, Tarassovi and Icterohaemorrhagiae were the principal serogroups which reacted in the tests. A total of 3,195 pigs were tested, of which 20.2% showed positive reactions. The mai...
Weiss DJ, Evanson OA, MacLeay J, Brown DR.To determine whether mucosal permeability is altered during the prodromal stages of alimentary laminitis. Methods: 15 healthy adult ponies. Methods: intestinal permeability was evaluated for control ponies (n = 5) and for ponies 4 to 12 (n = 5) and 20 to 28 (n = 5) hours after administration of carbohydrate overload. Mucosal permeability was determined by measuring the percentage of orally administered technetium Tc99m diethylenetriaminopentaacetate (99mTc-DTPA) excreted in urine during an 8-hour period, then measuring blood radioactivity at hourly intervals. Plasma endotoxin-like activity was...
Mainar-Jaime RC, House JK, Smith BP, Hird DW, House AM, Kamiya DY.To predict mortality of horses by use of clinical data from the first day of hospitalization, to determine whether fecal shedding of Salmonella organisms is related to severity of clinical disease, and to determine the impact of fecal shedding of Salmonella organisms on mortality. Methods: Prospective study. Methods: 1,446 hospitalized horses. Methods: Medical information was obtained from horses hospitalized in an intensive care unit or isolation facility during a 4.5-year period. A model was created to predict mortality, using covariates determined on the day of admission. Predicted mortalit...
Ward CL, Wood JL, Houghton SB, Mumford JA, Chanter N.Seventy-three bacterial isolates from 65 horses with and without evidence of lower airway disease were identified to assess whether the association with disease was accounted for by a small or large number of species. Just over half (50.5 per cent were Actinobacillus equuli, 17.8 per cent were A suis-like, 11 per cent were Pasteurella pneumotropica, 8.2 per cent were A lignieresii, 6.8 per cent were P haemolytica and 5.5 per cent were P mairii. These results suggest that a range of Actinobacillus and Pasteurella species can be isolated from the lower airways of horses, with many of the isolate...
Meiswinkel R.During the 1996 summer season (January-April) in South Africa an estimated 500 horses died of African horse sickness (AHS); 80% of deaths were due to AHS virus serotypes 2 and 4. Nearly all cases occurred in the northern, north-eastern and central parts of South Africa. This study reports the first attempt to verify the involvement of the biting midge Culicoides imicola in a field outbreak of AHS in southern Africa. In light-trap collections made at 47 sites over 12 weeks, C. imicola comprised 94.2% of 4.78 million Culicoides. Culicoides imicola was the most prevalent of 34 species captured an...
el Hasnaoui H, el Harrak M, Tber A, Fikri A, Laghzaoui K, Bikour MH.An indirect fluorescent antibody (IFA) technique was used to screen and quantify antibodies against African horse sickness virus (AHSV) in equine sera. Results obtained with the IFA assay were compared directly with those obtained with standard complement fixation (CF) and virus neutralisation (VN) tests using horse sera from experimental studies and samples from the field. Positive fluorescent antibody titres were detected from as early as 7 days after primary vaccination and persisted for at least six months. The IFA technique offers a clear advantage over CF tests, where the antibodies are ...
Barnard BJ.Zebra are the only equine species native to South Africa. These animals roamed over much of the country in the 17th century when horses and donkeys were first imported. The first cases of African horse sickness (AHS) then occurred in the horses of hunters who entered zebra territory. AHS continued to occur on a country-wide basis until the beginning of the 20th century, though the number of outbreaks decreased as the populations of zebra collapsed through overhunting. For most of the 20th century almost all free-living zebra have been confined to the north-eastern parts of South Africa which a...
Lord CC, Woolhouse ME, Mellor PS.Factors affecting epidemics of African horse sickness in Spain were studied using a mathematical model. The model examined the likelihood of an epidemic after the introduction of the virus, and the effectiveness of vaccination strategies. Two host species (horses and donkeys) and one vector species (the biting midge Culicoides imicola) were included. A stratified random sampling method (Latin hypercube sampling) was used for sensitivity analysis of the likelihood of an epidemic. Systematic variation of vaccination parameters was used to consider alternative control strategies. In general, when...
Huovilainen A, Ek-Kommonen C.A serological study for antibodies against equine arteritis virus (EAV) in Finland was performed during 1996. All equine sera delivered to the Virology Unit at the National Veterinary and Food Research Institute were tested with a micro-neutralization test, using the Arvac strain as antigen. The study also included imported horses to evaluate EAV circulation in the countries of origin. Nucleocapsid gene sequences of 2 Finnish equine semen isolates were amplified with RT-PCR and sequenced. The genetic relationships of those isolates with strains isolated elsewhere in the world were analyzed. Th...
Holly EA, Bracci PM, Mueller BA, Preston-Martin S.Nineteen counties from San Francisco and Los Angeles, California and Seattle, Washington were the United States sites for a large population-based case-control study of childhood brain tumors (CBTs), sponsored by the National Cancer Institute. CBT patients who were 1 year and were first on a farm when they were < 6 months of age also had increased risk for CBTs (OR = 3.9, 95% CI = 1.2-13). A somewhat increased risk for CBTs was found for children of mothers who ever had worked on livestock farms compared with mothers who never had worked on a farm (OR = 7.4, 95% CI = 0.86-64, based on five...
Feder HM, Nelson RS, Cartter ML, Sadre I.A survey was performed to identify people who were exposed to a rabid pony and determine whether or not they received rabies postexposure prophylaxis (PEP). Sixty-one visitors who came in contact with the rabid pony were identified. These visitors heard about the rabid pony via the news media. Forty-five visitors were exposed during the 2 weeks before the pony died. Thirty-two of these 45 visitors received PEP. Thirty-one visitors had or may have had saliva contact to an open wound or mucosa and all 31 received PEP. Fourteen visitors had no saliva contact to a wound or mucosa and one received ...
Craven J, Bjørn H, Henriksen SA, Nansen P, Larsen M, Lendal S.This study reports on the prevalence of anthelmintic resistance in strongyles of horses in Denmark. Of 5 methods used for the calculation of faecal egg count reduction (FECR) the method recommended by the World Association for the Advancement of Veterinary Parasitology, for the detection of resistance in sheep was the most sensitive procedure for detecting resistance. Using this method benzimidazole resistance was detected on 33 of 42 farms (79%) examined. Pyrantel was tested on 15 farms and FECR tests indicate resistance on 3 (30%) farms. On 2 farms on which resistance to pyrantel was detecte...
Mumford EL, Traub-Dargatz JL, Salman MD, Collins JK, Getzy DM, Carman J.To develop a system to monitor and detect acute infections of the upper respiratory tract (i.e., nares, nasopharynx, and pharynx) in horses and to assess the association among specific viral infections, risk factors, and clinical signs of disease. Methods: Prospective study. Methods: 151 horses with clinical signs of acute infectious upper respiratory tract disease (IURD) from 56 premises in Colorado. Methods: Health management data, blood samples, and nasal or nasopharyngeal swab samples were obtained for 151 horses with clinical signs of acute IURD. Of these horses, 112 had an additional blo...
Doherr MG, Carpenter TE, Wilson WD, Gardner IA.The objective of this study is to describe the design, application and validity of a self-administered (mailed) questionnaire to collect data on potential risk factors for Corynebacterium pseudotuberculosis infection in California horses. Horses admitted to the UC Davis Veterinary Medical Teaching Hospital (VMTH) between 1 July 1992 and 30 June 1994 served as the study base for case identification and simple random sampling of 800 control horses. A questionnaire was mailed to owners of the study horses, followed by a reminder postcard and a second copy of a questionnaire. Data were collected o...
Paterson DL, Murray PK, McCormack JG.Twenty-three horses and three humans in Queensland, Australia, were infected with a novel member of the Paramyxoviridae family of viruses in two geographically distinct outbreaks. Two of the humans died-one died of rapid-onset respiratory illness, and the other died of encephalitis. The third infected human developed an influenza-like illness and made a complete recovery. All infected humans had close contact with sick horses. Since the two outbreaks occurred at sites 1,000 km apart and no known contact between the two groups of humans and horses occurred, extensive testing of animals and bird...
Arboviruses include mosquitoborne and tickborne agents that persist in nature in complex cycles involving birds or mammals, including humans. Arboviral infection can cause fever, headache, meningitis, encephalitis, and sometimes death. During 1996-1997, health departments in 19 states reported to CDC 286 confirmed or probable cases (eight fatal) of arboviral encephalitis in humans (132 cases in 1996 and 154 provisionally in 1997). Surveillance programs in 18 states detected enzootic arboviral activity in mosquito or sentinel or wild bird populations, and cases of arboviral disease were recogni...
Ponce Gordo F, Cuesta Bandera C.The Spanish sheep and horse strains of Echinococcus granulosus possess several differential characteristics in their metacestode stage. Cysts from sheep vary widely in size and fertility, but they usually have a thin cyst wall and, when fertile, a whitish hydatid sand formed by brood capsules and protoscoleces. Two types of infections have been observed in horses: one resembling that of sheep, caused by small, non-fertile cysts with a thin wall, and a second type caused by medium to large, always fertile cysts with a thick wall. In this latter case, hydatid sand is always dark brown in color a...
Ilobi CP, Nicolson C, Taylor J, Mumford JA, Wood JM, Robertson JS.Equine influenza viruses propagated in the laboratory in alternate hosts such as embryonated hens' eggs or mammalian cell culture have been analysed by HA sequencing and antigenically and their sequence compared to the original virus present in clinical material. In contrast to clinically derived human influenza virus which generally grows in MDCK cells without change, the data for equine influenza virus were less clear in that variants of equine virus were derived in both eggs and cells. The study indicated that the current use of eggs for equine influenza virus surveillance and vaccine produ...
Moretti A, Boncio L, Pasquali P, Fioretti DP.Ringworm infections in the principal domestic animals are a major public and veterinary health problem. The aetiology, epidemiology and symptomatology of these mycoses are quite heterogeneous and complex. In this context, the AA carried out an epidemiological study to investigate the prevalence of dermatophytes in two different animal species, horses (n = 200) belonging to 10 private stables and cattle (n = 1900) belonging to farms with different breeding purposes and management. With regard to horses the results showed a positive level of 9% and Trichophyton equinum was the major organism iso...
Brightwell G, Brown JM, Coates DM.Rt-PCR probes targeted to different gene sequences of VEE (Venezuelan equine encephalitis) virus strain TC-83 were assessed for their sensitivity, specificity and non-specific cross-reactivity. A generic VEE virus amplimer (VNSP4F2/VNSP4R2), targeted against nsP4 was identified, which was sensitive (detected at least 10 pfu) and robust (worked over a wide range of salt concentrations and annealing temperatures). An E2 amplimer designed against TC-83, (VE2F/VE2R), identified VEE strains TRD (1AB), P676 (1C), 3880 (1D) Everglades (2) vRNA whilst a second E2 primer pair designed against strain 68...
Van Andel AE, Magnarelli LA, Heimer R, Wilson ML.To characterize antibody response in horses with clinical signs of Ehrlichia equi infection. Methods: Prospective study. Methods: 13 horses with confirmed acute E equi infection. Methods: Sequential serum sampling was performed in Connecticut and New York during 1995 and 1996 to identify horses with naturally acquired equine granulocytic ehrlichiosis (EGE). Horses with clinical signs of EGE (i.e., fever without respiratory involvement) were confirmed as having E equi infection by polymerase chain reaction detection of ehrlichial DNA and by a minimum fourfold increase in total antibody titer by...
Rawlings P, Snow WF, Boorman J, Denison E, Hamblin C, Mellor PS.Twelve light trap collections made near overnight shelters of horses and donkeys in four villages in the Central River Division of The Gambia captured fourteen species of biting midge of the genus Culicoides. Five species new to The Gambia were identified. This brought the number of recognized species of Culicoides (after a revision of C. schultzei) to twenty-nine in The Gambia. Species known or suspected as vectors of African horse sickness virus (AHSV) and bluetongue virus (BTV) comprised 83% of female captures, 65% of captures being C. imicola or its sibling species, C. miombo. Captures of ...
Hall RF, Pursell AR, Cole JR, Youmans BC.An epizootic of equine infectious anemia (EIA) involved 35 horses on a farm in south Georgia. During a 126-day period, 21 of these horses became seropositive for EIA. After the initial diagnosis in July, the horses were tested every 7 to 10 days. At least one additional horse was found to be seropositive on each testing day. As soon as they were determined to be seropositive, the horses were removed from the herd and sent to slaughter. The removal of the seropositive horses, however, did not stop the epizootic. We believe the initial infection was from a 7-year-old stallion that recently had b...
Hughes K.Cases of Hendra virus infection in horses in Australia have been seen regularly since the virus was first isolated in 1994. Kristopher Hughes, associate professor of equine medicine at Charles Sturt University in Australia, gives an overview of how knowledge of the virus has developed in the past 20 years.
Raftery AG, Gummery L, Garcia K, Mohite D, Capewell P, Sutton DGM.Equine trypanosomiasis is a neglected protozoal disease. Objective: To perform a systematic search of literature to explore: (1) In equines what is the global geographical distribution and prevalence of trypanosomiasis? In low and middle-income countries (LMICs) is trypanosomiasis more prevalent than in higher-income countries (HICs)? (2) Is trypanosomiasis infection a significant contributor to global morbidity and mortality? Methods: Systematic review and meta-analyses. Methods: Studies were identified that described naturally occurring equine trypanosomiasis worldwide following 'Preferred R...
Paillot R, Regourd E, Behr-Gross ME.Equine influenza (EI) is an important respiratory disease of horses, with welfare and economic consequences. Vaccination remains one of the most efficient prevention methods available. Equine influenza virus (EIV) is constantly evolving and consequently EI vaccines need to be updated on a regular basis. In 2010, the World Organisation for Animal Health (OIE) Expert Surveillance Panel (ESP) on EI provided a new recommendation for EI vaccine strain composition, including the incorporation of representative EIV strains of both Florida Clade 1 and Clade 2 sub-lineages (FC1 and FC2, respectively). ...
Kamhieh S, Hodgson J, Bode L, Ludwig H, Ward C, Flower RL.Borna disease virus (BDV) is a unique RNA virus that is a cause of neurological disease in horses, sheep and cats. The finding that BDV also infects humans has raised concern related to the impact of infection with this virus. The extent to which BDV may be endemic in geographical regions outside Europe is of interest in management of international movement of animals including horses. Sera from Australian horses (N = 553) sampled in Sydney, New South Wales (NSW), were analysed for BDV antigen, circulating immune complexes (CICs), and antibodies by monoclonal antibody-based ELISAs. One-tenth o...
François AC, Renaud B, Kruse CJ, Marcillaud-Pitel C, Votion DM.Anne-Christine François, Benoît Renaud, Caroline-Julia Kruse, Christel Marcillaud-Pitel and Dominique-Marie Votion of the Atypical Myopathy Alert Group discuss insights from 20 years of research and surveillance on equine atypical myopathy.
Yu YT, Olarte Castillo X, Reboul G, Zehr J, Sun Y, Anderson R, Wang M, Sun Q, Tallmadge R, Sams K, Brown J, Marra N, Stanhope B, Grenier J.... is a parvovirus that was identified in the blood of four horses in the United States. Here, we report one genome from a horse in New York State. This genome may represent a new species within the genus .
Streng K, Holicki CM, Hesson JC, Graham H, Chandler F, Krol L, Blom R, Münger E, van der Linden A, Koenraadt CJM, Schrama M, de Saint Lary CB....We report Sindbis virus circulation in the Netherlands based on serologic evidence found in 6 resident wild birds and 3 horses (2021-2022). Tested mosquitoes were molecularly negative, and humans were serologically negative. Veterinarians and health practitioners in the Netherlands should be aware of the importance of surveillance for Sindbis virus.
Giangaspero A, Lia R, Vovlas N, Otranto D.A survey on the prevalence of Thelazia spp. in the province of Bari (Apulia region, Italy) in slaughtered native horses was conducted from June 20, 1995 to April 3, 1996. Both eyes from 409 ten-month- to 4-year-old native animals were examined. Sixty horses (14.7%) were found parasitized by Thelazia lacrymalis. Three hundred-sixty one parasite specimens (220 females, 99 males and 42 larvae) were collected with a mean count burden of 6.0-5.1 (range 1 to 20) per head. T. lacrymalis specimens were found free in the conjunctiva and behind the nictitancte, in the excretory ducts of the Harderian gl...
Ganbaatar O, Ganzorig S, Tseren-Ochir EO, Suzuki Y, Takai S.In 2024, 90 soil samples and 11 fecal samples were collected from nine Mongolian provinces. Using NANAT selective agar, R. equi was successfully isolated from 23 soil samples (25.6%) across five provinces and from three fecal samples (27.3%) collected in two provinces. A total of 122 isolates were identified as R. equi via choE-targeted polymerase chain reaction (PCR) and subsequently screened for virulence-associated genes (vapA, vapB, and vapN) by PCR. Of these, 17 isolates tested positive for the vapA gene, while the remaining 105 isolates were negative for both vapB and vapN. Plasmid prof...
Taylor P, Scarth JP, Hillyer LL.Within equine drug surveillance, there is significant interest in analyzing intact phase II conjugates of drugs in urine, but progress has been limited by a lack of reference material. Methods: In this study, in vitro techniques using equine liver fractions were employed to produce glucuronide and sulfate conjugates of stanozolol, 16β-hydroxystanozolol and nandrolone, the glucuronide conjugate of morphine and the glutathione metabolite of chlordinitrobenzene for the first time in equine sports drug surveillance. Results: The glucuronide conjugate of the synthetic progestagen altrenogest was a...
Müntener C, Kupper J, Naegeli H, Gassner B.A total of 292 adverse reactions to veterinary medicinal products were reported during the year 2015. This represents an increase of 9% compared to the previous year (268 reports). Similar to previous years, most of the reactions reported were linked to the use of antiparasitics (55.1%), non-steroidal anti-inflammatory products (8.9%) or antiinfectives (9.3%). The affected animal species were primarily dogs (198 reports) and cats (42 reports), followed by cattle (31 reports) and horses (8 reports). Additional 42 reports were provided within the frame of consultations with Tox Info Suisse in ZÃ...
Giles C, Cavanagh HM, Noble G, Vanniasinkam T.There are currently two known serotypes of equine adenovirus (EAdV), equine adenovirus type 1 (EAdV1) and equine adenovirus type 2 (EAdV2); EAdV1 is predominantly associated with upper respiratory tract infections while EAdV2 appears to have a higher association with gastrointestinal infection, however, very little is known about the prevalence of these viruses in horse populations in Australia. In this study we tested 122 serum samples obtained from horses in New South Wales, Australia, using a standard serum neutralization (SN) assay and ELISA. Ninety-seven of the 122 sera displayed had mode...
Sebek Z, Wallner H, Sixl W, Kaaserer G, Valová M.Results are presented of a serological examination of 1,547 domestic animals (cattle, pig, sheep, horse, goat, dog, cat) from 9 Tyrolian districts (Austria), performed in order to disclose the incidence of leptospirosis. Completely significant titres were domonstrated by means of the MAL test in the serotypes icterohaemorrhagiae or copenhageni, sorex-jalna, bratislava, sejroe and saxkoebing. In addition, antibodies were confirmed against L. bataviae, L. pomona, L. tarassovi and L. bulgarica, but the titres were insignificant. Of the animals examined, 7.2% gave positive reactions in titres of 1...
Goto H, Shimizu K, Abe T, Kanamitsu M.A serological survey was conducted on horse sera collected for 7 years just before the first outbreak of equine influenza (EI) infection in Japan in 1971. No antibodies against the A/Equi-1/Prague/56 (equi-1) and A/Equi-2/Miami/63 (equi-2) strains of EI virus were detected in any of the sera of 452 native horses when employing hemagglutination inhibition (HI) and complement fixation (CF) tests against viral (V) antigen. On the contrary, of the 80 imported horses, 48 (60.0%) had HI titers of 1:8 or higher against equi-1 and 23 (28.8%) against equi-2. In the CF-V test 42.6% of the horses showed ...
Bertone AL.With large colon resection and anastomosis, up to 95 per cent of the length of the large colon has been successfully removed. A hand-sewn end-to-end anastomosis is effective for lesions in the left dorsal colon and pelvic flexure. Transection and a side-to-side anastomosis with stapling equipment is most effective for extensive resections (greater than 50 per cent). Horses with extensive colon resection (95 per cent) have permanent deficiencies of water absorption and digestion of cellulose and protein. Fermentative capacity is reduced, owing to decreased particulate matter retention time in t...
Mouncey R, Arango-Sabogal JC, de Mestre AM, Verheyen KL.Up-to-date estimates of early-life morbidity and mortality in Thoroughbreds are lacking. Methods: A birth cohort was established on Thoroughbred stud farms across the UK and Ireland. All veterinary interventions for disease or injury between birth and 18 months of age or leaving the study were recorded. Multilevel Poisson regression models with farm and foal as random effects were fitted to estimate incidence rates. Results: Data were available for 3328 foal-months at risk for 275 foals on seven farms. The overall rates of disease and injury requiring veterinary intervention and mortality were...
Gibson MJ, Legg KA, Gee EK, Rogers CW.After establishing a baseline of stipendiary stewards' reporting using the paper-based system in the 2015/16 and 2016/17 seasons of harness racing, it is important to examine if the implementation of an online system has altered frequency and descriptors used for clinical outcomes. The objective of this study was to describe the race level injury and reporting outcomes, and horse- and race-level variables associated with the rate of the reporting of these outcomes during the 2019/20 and2020/21 harness racing seasons in New Zealand. The introduction of the online system was associated with few ...
Chambers TM, Reedy SE.In horses, presumptive diagnosis of equine influenza is commonly made on the basis of clinical signs. This alone is insufficient for confirmation of equine influenza, because other equine infectious respiratory diseases can in some degree have similar clinical presentations. Surveillance and control of equine influenza also necessitate detection of subclinical cases. Effective diagnosis of equine influenza virus infection is critically dependent on obtaining adequate specimens of virus-containing respiratory secretions for testing. These specimens are also valuable as sources for isolation of ...
Walton TE, Holbrook FR, Bolivar-Raya R, Ferrer-Romero J, Ortega MD.The arthropod-borne virus (arbovirus) diseases of livestock have worldwide impact. The prevention of an introduction of an exotic disease and the control of one subsequent to an introduction will require the attention, cooperation, and support of the livestock industry, regulatory agencies, and researchers. The most effective protection of our livestock industries is to prevent the introduction of an exotic disease agent. This implies complete restriction of animal imports and exports. However, "zero risk" is an unacceptable option in today's world of internationally integrated and interdepend...
Drudge JH, Lyons ET, Tolliver SC, Fallon EH.Clinical trials on a central Kentucky Thoroughbred Farm (B) during 1960-1961 involved nine test treatments of mares, yearlings and weanlings (n = 124), and compared efficacies of phenothiazine (PTZ), piperazine (PPZ), mixtures of PTZ + PPZ and thiabendazole (TBZ) for (1) percent reduction and (2) complete clearance or graded reduction of strongyle egg per gram (epg) counts. Three grades of PTZ (N.F. green, micronized purified and 2-3 microns purified) at the dose rate of 55 mg kg-1 were ineffective in six tests; reduction of strongyle epg count were low grade (26%) and complete clearance was f...
Niwa H, Higuchi T, Fujii S, Kinoshita Y, Uchida-Fujii E, Sueyoshi M, Nukada T, Ueno T.Equine proliferative enteropathy (EPE) is an equine infectious disease that can lead to severe weight loss and hyperplasia of the intestinal mucosa due to infection with Lawsonia intracellularis. In this study, we investigated the prevalence of EPE in a major Thoroughbred breeding area: Hidaka district, Hokkaido, Japan. Of the 252 symptomatic horses that we tested, 192 EPE cases (76.2%), including 8 fatal cases, were confirmed from April 2015 to March 2020 by etiological and/or serological investigation. Most of the EPE cases were observed in foals (88.5%), with fewer cases in yearlings (7.3%)...