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Topic:Disease Transmission

Disease transmission in horses refers to the spread of infectious agents such as bacteria, viruses, fungi, and parasites among equine populations. These pathogens can be transmitted through various routes, including direct contact, vector-borne transmission, or environmental exposure. Factors influencing disease transmission include horse density, management practices, and biosecurity measures. Understanding the mechanisms and conditions that facilitate the spread of diseases is essential for developing effective prevention and control strategies. This page compiles peer-reviewed research studies and scholarly articles that investigate the modes of transmission, risk factors, and management practices related to infectious diseases in horses.
Surveillance for nosocomial infections in veterinary hospitals.
The Veterinary clinics of North America. Equine practice    November 3, 2004   Volume 20, Issue 3 561-vii doi: 10.1016/j.cveq.2004.08.002
Morley PS.Surveillance for nosocomial infection and disease is a critical component in an integrated and highly effective infection control program. Surveillance activities provide a sensory role to guide ongoing control practices so that they are focused and efficient. Without input from surveillance results, infection control practices are likely to be guided more by emotion and opinion than by data and evidence. This article discusses issues to be considered when developing effective nosocomial infection surveillance programs as well as the historical perspective of surveillance efforts for nosocomia...
Equine herpesvirus 1 and 4.
The Veterinary clinics of North America. Equine practice    November 3, 2004   Volume 20, Issue 3 631-642 doi: 10.1016/j.cveq.2004.09.001
Reed SM, Toribio RE.Equine herpesvirus infections in horses remain a significant cause of abortion and neurologic disease. These viruses are also responsible for mild signs of respiratory disease. The ability to establish latent infections with periodic reactivation or transmission to other horses is an important feature of these herpesviruses. One of the most unique aspects of this report is the description of horses demonstrating neurologic signs serving as the source of infection for other horses. Accurate diagnosis and better means of protection for horses remain problems facing veterinarians and horse owners...
Methicillin-resistant Staphylococcus aureus in horses and horse personnel.
The Veterinary clinics of North America. Equine practice    November 3, 2004   Volume 20, Issue 3 601-613 doi: 10.1016/j.cveq.2004.07.009
Weese JS.Fortunately, MRSA infection and colonization are currently uncommon in veterinary medicine. Nevertheless, the increasing reports of the occurrence of MRSA infection in horses, veterinarians, and equine personnel dictate that serious consideration be given to the control of this pathogen in veterinary hospitals as well as in the equine community. It is unclear whether extrapolation from human hospitals and people in the community is appropriate; however, given the rapid increase in nosocomial MRSA in human hospitals and the recent shift of certain clones of MRSA into the community, it would be ...
Evolution of equine infection control programs.
The Veterinary clinics of North America. Equine practice    November 3, 2004   Volume 20, Issue 3 521-v doi: 10.1016/j.cveq.2004.07.002
Smith BP.The science of control of infectious diseases in hospitals was born in 1847 when Semmelweis, a physician, ordered his medical students to scrub their hands in chlorinated lime water between patients and demonstrated that this simple procedure resulted ina dramatic decline in patient morbidity and mortality. In the late nineteenth century came huge breakthroughs in the understanding that microorganisms cause many disorders, and methods to eliminate and control these microorganisms were attempted. By 1910, sterile instruments, gowns, masks, and gloves had become standard for surgical procedures ...
Clostridium difficile diarrhea: infection control in horses.
The Veterinary clinics of North America. Equine practice    November 3, 2004   Volume 20, Issue 3 615-630 doi: 10.1016/j.cveq.2004.07.005
Båverud V.C difficile has emerged as an important cause of diarrheic disease in horses. C difficile diarrhea is usually diagnosed in mature horses, mostly when they are treated with antimicrobials and hospitalized. It is important for clinicians at veterinary hospitals to have knowledge about the organism and the infection. To prevent C difficile diarrhea, judicious use of antimicrobials is important, as is minimizing different stress factors at the animal hospital or clinic. Infected horses must be isolated. Routine examination for C difficile and toxin A or B is recommended in horses with antibiotic-a...
Barrier precautions, isolation protocols, and personal hygiene in veterinary hospitals.
The Veterinary clinics of North America. Equine practice    November 3, 2004   Volume 20, Issue 3 543-559 doi: 10.1016/j.cveq.2004.07.006
Weese JS.Because nosocomial and zoonotic diseases are inherent and ever-present risks in veterinary hospitals, proactive policies should be in place to reduce the risk of sporadic cases and outbreaks. Policies should ideally be put in place before disease issues arise, and policies should be effectively conveyed to all relevant personnel. Written policies are required for practical and liability reasons and should be reviewed regularly. Although no infection control program can eliminate disease concerns, proper implementation of barrier precautions and isolation can reduce the exposure of hospitalized...
Multidrug-resistant Salmonella and nosocomial infections.
The Veterinary clinics of North America. Equine practice    November 3, 2004   Volume 20, Issue 3 587-600 doi: 10.1016/j.cveq.2004.07.008
Dargatz DA, Traub-Dargatz JL.Nosocomial infections are a serious threat to optimum patient care. In addition, nosocomial infections can have far-reaching consequences for the hospital personnel and the financial aspects of the hospital. Nosocomial infections with Salmonella spp have been described among hospitalized equine populations more frequently than any other agent. Salmonella spp associated with hospitalized equids often possess more antimicrobial resistance determinants than do Salmonella spp isolated from healthy horses in the general population. There is little evidence to suggest that resistant salmonellae are ...
Equine cyathostomins.
Veterinary parasitology    October 28, 2004   Volume 125, Issue 1-2 203-220 doi: 10.1016/j.vetpar.2004.05.014
Matthews JB, Dowdall SM, Baudena MA, Klei TR, Kaplan RM, von Samson-Himmelstjerna G, Drögemüller M, Schnieder T.This collection of articles provides an in depth account of five presentations delivered during the Symposium on Equine Cyathostomins held at the 19th International Conference of the World Association for the Advancement of Veterinary Parasitology (WAAVP), New Orleans, Louisiana,10–14 August 2003. The symposium was organized and chaired by Ray M. Kaplan and Jacqui B. Matthews and focused on new developments in two major areas of current importance: the immunobiology of cyathostomin–horse interactions and anthelmintic resistance.
Enzootiology of Trypanosoma evansi in Pantanal, Brazil.
Veterinary parasitology    October 16, 2004   Volume 125, Issue 3-4 263-275 doi: 10.1016/j.vetpar.2004.07.013
Herrera HM, Dávila AM, Norek A, Abreu UG, Souza SS, D'Andrea PS, Jansen AM.In order to better understand the enzootiology of trypanosomiasis caused by Trypanosoma evansi in the Brazilian Pantanal we examined domestic and wild mammals by microhematocrit centrifuge technique (MHCT), immunofluorescence antibody test (IFAT) and polymerase chain reaction (PCR). T. evansi infection was detected in all species sampled with exception of the sheep and the feral pig. High parasitemias were observed in capybaras (5/24), coatis (18/115), horses (31/321) and dogs (3/112). Among these species, only the capybaras did not develop anemia. Low parasitemias, only detected by PCR, were ...
[West Nile virus also in the Netherlands?].
Tijdschrift voor diergeneeskunde    October 6, 2004   Volume 129, Issue 17 561 
Goehring L, Sloet M, Rottier P, Koopmans M, Godeke GJ, Vennema H.No abstract available
Phenotypic characterization of Brucella strains isolated from livestock in Nigeria.
Veterinary microbiology    September 24, 2004   Volume 103, Issue 1-2 47-53 doi: 10.1016/j.vetmic.2004.06.012
Ocholi RA, Kwaga JK, Ajogi I, Bale JO.Isolation of brucellae from aborted fetuses, hygroma fluids, milk and vaginal swabs obtained from aborting cattle, sheep, goats, pigs, and horses in Nigeria was carried out. A total of 25 isolates, obtained mainly from cattle, sheep and horses, were biotyped. All strains belonged to one species, Brucella abortus biovar 1. The epidemiological significance of this finding is discussed. Some preliminary observations on the zoonotic and public health implications of Brucella infection in Nigerian livestock are presented. A control programme involving improved management, animal movement restrictio...
Identification of reptilian and amphibian blood meals from mosquitoes in an eastern equine encephalomyelitis virus focus in central Alabama.
The American journal of tropical medicine and hygiene    September 24, 2004   Volume 71, Issue 3 272-276 
Cupp EW, Zhang D, Yue X, Cupp MS, Guyer C, Sprenger TR, Unnasch TR.Uranotaenia sapphirina, Culex erraticus, and Cx. peccator were collected in an enzootic eastern equine encephalomyelitis (EEE) virus focus in central Alabama (Tuskegee National Forest) from 2001 to 2003 and analyzed for virus as well as host selection. EEE virus was detected in each species every year except 2003, when pools of Cx. peccator were negative. Most (97%) of the 130 Cx. peccator blood meals identified were from ectothermic hosts; 3% were from birds. Among blood meals from reptiles (approximately 75% of the total), 81% were from Agkistrodon piscivorus (cottonmouth); all amphibian blo...
Glycogen branching enzyme (GBE1) mutation causing equine glycogen storage disease IV.
Mammalian genome : official journal of the International Mammalian Genome Society    September 16, 2004   Volume 15, Issue 7 570-577 doi: 10.1007/s00335-004-2369-1
Ward TL, Valberg SJ, Adelson DL, Abbey CA, Binns MM, Mickelson JR.Comparative biochemical and histopathological evidence suggests that a deficiency in the glycogen branching enzyme, encoded by the GBE1 gene, is responsible for a recently identified recessive fatal fetal and neonatal glycogen storage disease (GSD) in American Quarter Horses termed GSD IV. We have now derived the complete GBE1 cDNA sequences for control horses and affected foals, and identified a C to A substitution at base 102 that results in a tyrosine (Y) to stop (X) mutation in codon 34 of exon 1. All 11 affected foals were homozygous for the X34 allele, their 11 available dams and sires w...
Epidemiology of Trichinella infection in the horse: the risk from animal product feeding practices.
Veterinary parasitology    August 25, 2004   Volume 123, Issue 3-4 223-233 doi: 10.1016/j.vetpar.2004.06.008
Murrell KD, Djordjevic M, Cuperlovic K, Sofronic Lj, Savic M, Djordjevic M, Damjanovic S.A discovery in 2002 of a Trichinella spiralis-infected horse in Serbia offered an opportunity to conduct needed epidemiological studies on how horses, considered herbivores, acquire a meat-borne parasite. This enigma has persisted since the first human outbreaks from infected horse meat occurred in then 1970s. The trace back of the infected horse to a farm owner was carried out. Interviews and investigations on the farm led to the conclusion that the owner had fed the horse food waste in order to condition the horse prior to sale. Further investigations were then carried out to determine the f...
Isolation of methicillin-resistant Staphylococcus aureus from the environment in a veterinary teaching hospital.
Journal of veterinary internal medicine    August 24, 2004   Volume 18, Issue 4 468-470 doi: 10.1892/0891-6640(2004)182.0.co;2
Weese JS, DaCosta T, Button L, Goth K, Ethier M, Boehnke K.After recognition of a cluster of methicillin-resistant Staphylococcus aureus (MRSA) infection in horses and humans at the Ontario Veterinary College Veterinary Teaching Hospital, environmental contamination with MRSA was evaluated. A total of 260 environmental surfaces were sampled during periods when MRSA-infected horses were hospitalized, and MRSA was isolated from 25/260 sites (9.6%). The most commonly contaminated sites were stalls housing MRSA-positive horses, but other stalls, medical equipment, personal items, and equine restraint devices also were contaminated. The role of the environ...
The effects of strain heterology on the epidemiology of equine influenza in a vaccinated population.
Proceedings. Biological sciences    August 13, 2004   Volume 271, Issue 1548 1547-1555 doi: 10.1098/rspb.2004.2766
Park AW, Wood JL, Daly JM, Newton JR, Glass K, Henley W, Mumford JA, Grenfell BT.We assess the effects of strain heterology (strains that are immunologically similar but not identical) on equine influenza in a vaccinated population. Using data relating to individual animals, for both homologous and heterologous vaccinees, we estimate distributions for the latent and infectious periods, quantify the risk of becoming infected in terms of the quantity of cross-reactive antibodies to a key surface protein of the virus (haemagglutinin) and estimate the probability of excreting virus (i.e. becoming infectious) given that infection has occurred. The data suggest that the infectio...
Amblyomma cajennense ticks induce immediate hypersensitivity in horses and donkeys.
Experimental & applied acarology    August 3, 2004   Volume 33, Issue 1-2 109-117 doi: 10.1023/b:appa.0000030016.33747.99
Szabó MP, Castagnolli KC, Santana DA, de Castro MB, Romano MA.Since host immune reaction to ticks interferes with tick-borne pathogen transmission, it is important to recognize naturally occurring tick-host immune relationships to better understand the epidemiology of such infectious diseases. Amblyomma cajennense is an important tick-borne disease vector in the Neotropical region and horses maintain it in domestic environments. In the present work intradermal testing of A. cajennense tick exposed horses and donkeys using crude tick antigens was used to evaluate the type of hypersensitivity induced by infestations. Animals sensitized by A. cajennense inf...
Equine viral vaccines: the past, present and future.
Veterinary research    July 9, 2004   Volume 35, Issue 4 425-443 doi: 10.1051/vetres:2004019
Minke JM, Audonnet JC, Fischer L.The increasing international movement of horses combined with the relaxation of veterinary regulations has resulted in an increased incidence of equine infectious diseases. Vaccination, along with management measures, has become the primary method for the effective control of these diseases. Traditionally modified live and inactivated vaccines have been used and these vaccines have proven to be very successful in preventing disease. However, there are a number of equine infectious diseases for which conventional technology has shown its limitations. The advent of recombinant technology has sti...
West Nile virus infection of horses.
Veterinary research    July 9, 2004   Volume 35, Issue 4 467-483 doi: 10.1051/vetres:2004022
Castillo-Olivares J, Wood J.West Nile virus (WNV) is a flavivirus closely related to Japanese encephalitis and St. Louis encephalitis viruses that is primarily maintained in nature by transmission cycles between mosquitoes and birds. Occasionally, WNV infects and causes disease in other vertebrates, including humans and horses. West Nile virus has re-emerged as an important pathogen as several recent outbreaks of encephalomyelitis have been reported from different parts of Europe in addition to the large epidemic that has swept across North America. This review summarises the main features of WNV infection in the horse, ...
Haemolysins of Salmonella, their role in pathogenesis and subtyping of Salmonella serovars.
Indian journal of experimental biology    July 6, 2004   Volume 42, Issue 3 303-313 
Singh BR, Singh VP, Agarwal M, Sharma G, Chandra M.Haemolysin patterns of 175 strains of different Salmonella enterica subspecies enterica serovars isolated from different animal sources and places were determined using 11 different blood agar media made with either non-washed horse/sheep erythrocytes or with washed erythrocytes of cattle, sheep, horse, goat, rabbit, guinea pig, and human A, O and B blood groups. Study on 47 strains belonging to 10 serovars of Salmonella from buffalo meat (buffen), 42 strains of 11 serovars from goat meat (chevon): 16 strains of Salmonella enterica serovar Paratyphi B and 25 of S. enterica serovar Paratyphi B ...
First case of equine nocardioform placentitis caused by Crossiella equi in Europe.
The Veterinary record    June 25, 2004   Volume 154, Issue 23 730-731 doi: 10.1136/vr.154.23.730
Cattoli G, Vascellari M, Corrò M, Capua I, Mutinelli F, Sells SF, Donahue JM.No abstract available
[Voorjaarsdagen (Spring Days) 2004: the horse].
Tijdschrift voor diergeneeskunde    June 24, 2004   Volume 129, Issue 11 372-374 
Reijerkerk E, Westermann C.No abstract available
Assessment of electrical charge on airborne microorganisms by a new bioaerosol sampling method.
Journal of occupational and environmental hygiene    June 19, 2004   Volume 1, Issue 3 127-138 doi: 10.1080/15459620490424357
Lee SA, Willeke K, Mainelis G, Adhikari A, Wang H, Reponen T, Grinshpun SA.Bioaerosol sampling is necessary to monitor and control human exposure to harmful airborne microorganisms. An important parameter affecting the collection of airborne microorganisms is the electrical charge on the microorganisms. Using a new design of an electrostatic precipitator (ESP) for bioaerosol sampling, the polarity and relative strength of the electrical charges on airborne microorganisms were determined in several laboratory and field environments by measuring the overall physical collection efficiency and the biological collection efficiency at specific precipitation voltages and po...
Use of a real-time polymerase chain reaction-based fluorogenic 5′ nuclease assay to evaluate insect vectors of Corynebacterium pseudotuberculosis infections in horses.
American journal of veterinary research    June 17, 2004   Volume 65, Issue 6 829-834 doi: 10.2460/ajvr.2004.65.829
Spier SJ, Leutenegger CM, Carroll SP, Loye JE, Pusterla JB, Carpenter TE, Mihalyi JE, Madigan JE.To develop and use a sensitive molecular assay for detecting the phospholipase D (PLD) exotoxin gene of Corynebacterium pseudotuberculosis in an attempt to identify insect vectors that may be important in transmission of clinical disease in horses. Methods: 2,621 flies of various species. Methods: A real-time polymerase chain reaction (PCR)-based fluorogenic 5' nuclease (TaqMan) system (ie, TaqMan PCR assay) was developed for the detection of the PLD gene in insects. Flies were collected monthly (May to November 2002) from 5 farms in northern California where C. pseudotuberculosis infection in...
Seasonal development of Cyathostominae larvae on pasture in a northern temperate region of the United Kingdom.
Veterinary parasitology    May 25, 2004   Volume 119, Issue 4 307-318 doi: 10.1016/j.vetpar.2003.11.014
Ramsey YH, Christley RM, Matthews JB, Hodgkinson JE, McGoldrick J, Love S.A study following the development of Cyathostominae from egg to the infective larval third stage was conducted from April to December 2001 in west central Scotland. Duplicate samples (1 kg) of naturally infected faeces were placed on a 78 cm2 plot each week on a cyathostomin-free pasture. Subsamples of the grass surrounding the faecal plot were collected weekly on four occasions and the number of larvae obtained determined. Few larvae were recovered in the first week of development of individual plots, followed by a rise in the numbers of larvae in second, third and fourth weeks of development...
Equine hyperlipaemia: a review.
Australian veterinary journal    April 20, 2004   Volume 82, Issue 3 136-142 doi: 10.1111/j.1751-0813.2004.tb12636.x
Hughes KJ, Hodgson DR, Dart AJ.No abstract available
Exotic Animal Diseases Bulletin.
Australian veterinary journal    April 20, 2004   Volume 82, Issue 1-2 16-17 doi: 10.1111/j.1751-0813.2004.tb14623.x
No abstract available
Transplacental transmission of Theileria equi in two foals born and reared in the United Kingdom.
The Veterinary record    April 16, 2004   Volume 154, Issue 13 406-408 doi: 10.1136/vr.154.13.406
Phipps LP, Otter A.No abstract available
Study of faecal shedding of Clostridium difficile in horses treated with penicillin.
Equine veterinary journal    March 25, 2004   Volume 36, Issue 2 180-182 doi: 10.2746/0425164044868657
Gustafsson A, Båverud V, Gunnarsson A, Pringle J, Franklin A.No abstract available
Alternate circulation of recent equine-2 influenza viruses (H3N8) from two distinct lineages in the United States.
Virus research    March 17, 2004   Volume 100, Issue 2 159-164 doi: 10.1016/j.virusres.2003.11.019
Lai AC, Rogers KM, Glaser A, Tudor L, Chambers T.Phylogenetic and antigenic analyses indicate that recent circulating equine-2 influenza viruses in the United States have been alternating between two genetic and antigenic distinct lineages since 1996. The evolution rates for these two lineages, the Kentucky and the Florida lineage, are very similar. For the earlier isolates in the Kentucky lineage, there are multiple and sequential nonsynonymous substitutions at antigenic sites B and D. However, there are no changes at any of these antigenic sites for KY98 and OK00. In the Florida lineage, except for NY99 with one amino acid substitution at ...
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