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Topic:Epidemiology

Epidemiology in horses involves the study of the distribution and determinants of health-related states and events in equine populations. It encompasses the investigation of patterns, causes, and effects of diseases and health conditions within horse populations. This field of study aims to identify risk factors for disease and targets for preventive healthcare. Key components of equine epidemiology include disease surveillance, outbreak investigation, and the study of disease dynamics within herds or regions. Research in this area often focuses on infectious diseases, zoonotic diseases, and the impact of environmental factors on equine health. This page compiles peer-reviewed research studies and scholarly articles that explore various aspects of epidemiology in horses, including disease prevalence, transmission pathways, and strategies for disease prevention and control.
A survey of respiratory viruses in New Zealand horses.
New Zealand veterinary journal    February 21, 2013   Volume 61, Issue 5 254-261 doi: 10.1080/00480169.2012.745211
McBrearty KA, Murray A, Dunowska M.To determine which viruses circulate among selected populations of New Zealand horses and whether or not viral infections were associated with development of respiratory disease. Methods: Nasal swabs were collected from 33 healthy horses and 52 horses with respiratory disease and tested by virus isolation and/or PCR for the presence of equine herpesviruses (EHV) and equine rhinitis viruses. Results: Herpesviruses were the only viruses detected in nasal swab samples. When both the results of nasal swab PCR and virus isolation were considered together, a total of 41/52 (79%) horses with respirat...
A large scale molecular study of Giardia duodenalis in horses from Colombia.
Veterinary parasitology    February 21, 2013   Volume 196, Issue 1-2 31-36 doi: 10.1016/j.vetpar.2013.02.006
Santín M, Cortés Vecino JA, Fayer R.The prevalence of Giardia duodenalis assemblages in horses is poorly known. The present study examined feces from 195 horses, 1 month-17 years of age, in 4 locations in Colombia. Prevalence of infection was determined by PCR and all positives were sequenced to determine the genotypes. Thirty four (17.4%) horses were found positive. This is the first report of G. duodenalis in horses from Colombia. Prevalence in female and male horses was 18.9% and 15.1%, respectively. Prevalence in horses 1 year of age was 21.1% and 15.1%, respectively. Molecular characterization using the beta giardin (bg), g...
Horse-, training- and race-level risk factors for palmar/plantar osteochondral disease in the racing Thoroughbred.
Equine veterinary journal    February 20, 2013   Volume 45, Issue 5 582-586 doi: 10.1111/evj.12038
Pinchbeck GL, Clegg PD, Boyde A, Barr ED, Riggs CM.Palmar/plantar osteochondral disease (POD) is a common, debilitating condition in Thoroughbred racehorses; however, training- and racing-related factors associated with this disease are unknown. Objective: To determine horse-, racing- and training-related risk factors for POD. The general hypotheses were that early training and racing, and increased intensity of racing and training, lead to increased severity of POD. Methods: The metacarpo/metatarsophalangeal joints of 164 Thoroughbred racehorses were examined at post mortem and graded for third metacarpal and metatarsal POD. The relationships...
Quantitative versus qualitative approaches: a comparison of two research methods applied to identification of key health issues for working horses in Lesotho.
Preventive veterinary medicine    February 20, 2013   Volume 108, Issue 4 313-320 doi: 10.1016/j.prevetmed.2012.11.008
Upjohn MM, Attwood GA, Lerotholi T, Pfeiffer DU, Verheyen KL.The relative merits and potential complementarity of participatory methods and classical epidemiological techniques in veterinary-related research is a current topic of discussion. Few reported studies have applied both methodologies within the same research framework to enable direct comparison. The aim of this study was to compare issues identified by a classical epidemiological study of horses and their owners with those identified by owner communities using participatory approaches. In 2009, a cross-sectional survey was undertaken as part of an impact assessment study of farrier and saddle...
Salmonella Oranienburg isolated from horses, wild turkeys and an edible home garden fertilized with raw horse manure.
Zoonoses and public health    February 20, 2013   Volume 61, Issue 1 64-71 doi: 10.1111/zph.12043
Jay-Russell MT, Madigan JE, Bengson Y, Madigan S, Hake AF, Foley JE, Byrne BA.In July 2010, a horse from a rural farm (Farm A) in coastal Northern California was diagnosed with Salmonella Oranienburg infection following referral to a veterinary hospital for colic surgery. Environmental sampling to identify potential sources and persistence of Salmonella on the farm was conducted from August 2010 to March 2011. Salmonella was cultured using standard enrichment and selective plating. Pure colonies were confirmed by biochemical analysis, serotyped and compared by pulsed-field gel electrophoresis (PFGE) analysis. A total of 204 clinical and environmental samples at Farm A w...
Genetic divergence among members of the Kokobera group of flaviviruses supports their separation into distinct species.
The Journal of general virology    February 20, 2013   Volume 94, Issue Pt 7 1462-1467 doi: 10.1099/vir.0.049940-0
May FJ, Clark DC, Pham K, Diviney SM, Williams DT, Field EJ, Kuno G, Chang GJ, Cheah WY, Setoh YX, Prow NA, Hobson-Peters J, Hall RA.The Kokobera virus group comprises mosquito-borne flaviviruses that cluster together phylogenetically. These viruses are unique to Australia and Papua New Guinea, and have been associated with a mild polyarticular disease in humans. Recent isolation of genetically diverse viruses within this group has prompted analysis of their genetic and phenotypic relationships. Phylogenetic analysis based on complete ORF, the envelope gene or the NS5/3' untranslated region supported the separation of the group into distinct species: Kokobera virus (KOKV), Stratford virus, New Mapoon virus, MK7979 and TS527...
Clinical and molecular features of methicillin-resistant, coagulase-negative staphylococci of pets and horses.
The Journal of antimicrobial chemotherapy    February 20, 2013   Volume 68, Issue 6 1256-1266 doi: 10.1093/jac/dkt020
Kern A, Perreten V.To determine the antibiotic resistance and fingerprint profiles of methicillin-resistant coagulase-negative staphylococci (MRCoNS) from animal infections among different practices and examine the history of antibiotic treatment. Methods: Isolates were identified by mass spectrometry and tested for antimicrobial resistance by broth dilution, microarrays and sequence analysis of the topoisomerases. Diversity was assessed by PFGE, icaA PCR and staphylococcal cassette chromosome mec (SCCmec), arginine catabolic mobile element (ACME) and multilocus sequence typing. Clinical records were examined re...
Investigation of the role of lesser characterised respiratory viruses associated with upper respiratory tract infections in horses.
The Veterinary record    February 19, 2013   Volume 172, Issue 12 315 doi: 10.1136/vr.100943
Pusterla N, Mapes S, Wademan C, White A, Hodzic E.No abstract available
Permissive summer temperatures of the 2010 European West Nile fever upsurge.
PloS one    February 19, 2013   Volume 8, Issue 2 e56398 doi: 10.1371/journal.pone.0056398
Paz S, Malkinson D, Green MS, Tsioni G, Papa A, Danis K, Sirbu A, Ceianu C, Katalin K, Ferenczi E, Zeller H, Semenza JC.In the summer of 2010, Europe experienced outbreaks of West Nile Fever (WNF) in humans, which was preceded by hot spells. The objective of this study was to identify potential drivers of these outbreaks, such as spring and summer temperatures, relative humidity (RH), and precipitation. Methods: Pearson and lag correlations, binary and multinomial logistic regressions were used to assess the relationship between the climatic parameters and these outbreaks. Results: For human morbidity, significant (<0.05) positive correlations were observed between a number of WNF cases and temperature, with...
Pathological and clinical features associated with palmar/plantar osteochondral disease of the metacarpo/metatarsophalangeal joint in Thoroughbred racehorses.
Equine veterinary journal    February 19, 2013   Volume 45, Issue 5 587-592 doi: 10.1111/evj.12036
Pinchbeck GL, Clegg PD, Boyde A, Riggs CM.Palmar/plantar osteochondral disease (POD) of the metacarpo/metatarsophalangeal (Mc/MtPh) joints is common in Thoroughbred racehorses, but there is little information on predilection sites, associated pathologies and clinical signs. Objective: To describe the distribution of POD at post mortem examination and to examine the association of POD with other pathologies and clinical histories. Methods: The Mc/MtPh joints of 102 Thoroughbred racehorses were examined post mortem. Gross pathology of associated osteochondral elements, suspensory ligament and flexor tendons was recorded. Clinical data w...
Risk factors for large colon volvulus in the UK.
Equine veterinary journal    February 17, 2013   Volume 45, Issue 5 558-563 doi: 10.1111/evj.12039
Suthers JM, Pinchbeck GL, Proudman CJ, Archer DC.Risk factors for large colon volvulus (LCV) in the horse have not been previously reported. Knowledge of these risk factors may allow the introduction of measures that could be taken to minimise the incidence of LCV. Objective: To investigate risk factors for LCV in the horse. Methods: A prospective, multicentre, unmatched case-control study was conducted over a 24 month period in the UK. Data on 69 cases and 204 control horses, from 4 veterinary hospitals, were obtained via telephone questionnaires. Multivariable logistic regression was used to identify associations between horse and manageme...
Autologous bone marrow mesenchymal stromal cells for regeneration of injured equine ligaments and tendons: a clinical report.
Research in veterinary science    February 16, 2013   Volume 95, Issue 1 272-277 doi: 10.1016/j.rvsc.2013.01.017
Renzi S, Riccò S, Dotti S, Sesso L, Grolli S, Cornali M, Carlin S, Patruno M, Cinotti S, Ferrari M.The use of Mesenchymal Stromal Cells (MSCs) in orthopedic practice has recently and rapidly acquired an important role. Therapies based on the use of MSCs for the treatment of acute injuries as well as chronic inflammatory disorders are gradually becoming clinical routine. These cells have demonstrated intriguing therapeutic potentialities (i.e.: inflammation control, tissue regeneration and pathological scar prevention), that have been taken into consideration for use in both human and veterinary medicine. In particular, horses represent high performance athletes considered models for human p...
“Bute” in horse meat presents very low risk to health, says England’s chief medical officer.
BMJ (Clinical research ed.)    February 15, 2013   Volume 346 f1066 doi: 10.1136/bmj.f1066
Wise J.No abstract available
Prevalence and genetic diversity of equine piroplasms in Tov province, Mongolia.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases    February 14, 2013   Volume 16 178-185 doi: 10.1016/j.meegid.2013.02.005
Munkhjargal T, Sivakumar T, Battsetseg B, Nyamjargal T, Aboulaila M, Purevtseren B, Bayarsaikhan D, Byambaa B, Terkawi MA, Yokoyama N, Igarashi I.Equine piroplasmosis represents a serious problem in horse industry. Although, researchers suggested the possible use of sub-unit vaccines to control equine piroplasmosis, the genetic diversity of vaccine candidate antigens was not properly investigated. In the present study, we screened 250 horses reared in three different districts of Tov province, Mongolia, for Babesia caballi and Theileria equi using ELISA and nested PCR (nPCR) assays. Among these animals, piroplasms were detected in 128 (51.2%) horses by nPCR assays (B. caballi, 42.4%; T. equi, 6.4%; and mixed infections, 2.4%), while 204...
Can Europe learn lessons from African horse sickness in Senegal?
The Veterinary record    February 12, 2013   Volume 172, Issue 6 150-151 doi: 10.1136/vr.f698
van den Boom R, Sloet van Oldruitenborgh-Oosterbaan MM.No abstract available
Comparison of an improved competitive enzyme-linked immunosorbent assay with the World Organization for Animal Health-prescribed serum neutralization assay for detection of antibody to Equine arteritis virus. Chung C, Wilson C, Timoney P, Adams E, Adams DS, Chung JS, Evermann JF, Shuck K, Lee SS, McGuire TC.Equine arteritis virus (EAV) causes contagious equine viral arteritis, characterized by fever, anorexia, conjunctivitis, nasal discharge, dependent edema, abortion, infrequent death in foals, and establishment of the carrier state in stallions. The World Organization for Animal Health (OIE) defines a horse as seropositive if the serum neutralization (SN) antibody titer is ≥1:4 to EAV. However, determining the SN titer is time-consuming and requires specific laboratory facilities, equipment, and technical expertise to perform. Furthermore, interpretation of the SN titer of some sera can be di...
Genetic characterization of Theileria equi infecting horses in North America: evidence for a limited source of U.S. introductions.
Parasites & vectors    February 11, 2013   Volume 6 35 doi: 10.1186/1756-3305-6-35
Hall CM, Busch JD, Scoles GA, Palma-Cagle KA, Ueti MW, Kappmeyer LS, Wagner DM.Theileria equi is a tick-borne apicomplexan hemoparasite that causes equine piroplasmosis. This parasite has a worldwide distribution but the United States was considered to be free of this disease until recently. Methods: We used samples from 37 horses to determine genetic relationships among North American T. equi using the 18S rRNA gene and microsatellites. We developed a DNA fingerprinting panel of 18 microsatellite markers using the first complete genome sequence of T. equi. Results: A maximum parsimony analysis of 18S rRNA sequences grouped the samples into two major clades. The first cl...
Characterization of anti-crotalic antibodies.
Toxicon : official journal of the International Society on Toxinology    February 8, 2013   Volume 66 7-17 doi: 10.1016/j.toxicon.2013.01.015
Guidolin FR, Tambourgi DV, Guidolin R, Marcelino JR, Okamoto CK, Magnoli FC, Queiroz GP, Dias da Silva W.Crotalus durissus terrificus, C. d. collilineatus, C. d. cascavella and C. d. marajoensis are responsible minor but severe snake bites in Brazil. The venoms of these snakes share the presence of crotoxin, a neurotoxin comprising of two associated components, crotapotin and phospholipase A2 (PLA2). Treatment of the victims with specific antiserum is the unique effective therapeutic measure. The ability of anti-Crotalus antisera produced by the routine using crude venom to immunize horses or purified crotoxin and PLA2 as individual immunogens was compared. Antisera obtained from horses immunized...
Case-control study of a multistate equine herpesvirus myeloencephalopathy outbreak.
Journal of veterinary internal medicine    February 7, 2013   Volume 27, Issue 2 339-346 doi: 10.1111/jvim.12051
Traub-Dargatz JL, Pelzel-McCluskey AM, Creekmore LH, Geiser-Novotny S, Kasari TR, Wiedenheft AM, Bush EJ, Bjork KE.A large multistate outbreak of equine herpesvirus myeloencephalopathy (EHM) occurred in May 2011 among horses that participated in a competitive event. Objective: To identify EHM risk factors among horses with a common exposure venue. Methods: A total of 123 horses: 19 horses with EHM, 14 equine herpesvirus-1 cases with no reported neurologic signs, and 90 control horses. Methods: EHM case survey data were compared with data from EHV-1 cases with no neurologic signs and healthy controls using univariable and multivariable methods. Results: Significant factors associated with higher risk for EH...
Complex inheritance of melanoma and pigmentation of coat and skin in Grey horses.
PLoS genetics    February 7, 2013   Volume 9, Issue 2 e1003248 doi: 10.1371/journal.pgen.1003248
Curik I, Druml T, Seltenhammer M, Sundström E, Pielberg GR, Andersson L, Sölkner J.The dominant phenotype of greying with age in horses, caused by a 4.6-kb duplication in intron 6 of STX17, is associated with a high incidence of melanoma and vitiligo-like skin depigmentation. However, the progressive greying and the incidence of melanoma, vitiligo-like depigmentation, and amount of speckling in these horses do not follow a simple inheritance pattern. To understand their inheritance, we analysed the melanoma grade, grey level, vitiligo grade, and speckling grade of 1,119 Grey horses (7,146 measurements) measured in six countries over a 9-year period. We estimated narrow sense...
Evolution of equine influenza virus in vaccinated horses.
Journal of virology    February 6, 2013   Volume 87, Issue 8 4768-4771 doi: 10.1128/JVI.03379-12
Murcia PR, Baillie GJ, Stack JC, Jervis C, Elton D, Mumford JA, Daly J, Kellam P, Grenfell BT, Holmes EC, Wood JL.Influenza A viruses are characterized by their ability to evade host immunity, even in vaccinated individuals. To determine how prior immunity shapes viral diversity in vivo, we studied the intra- and interhost evolution of equine influenza virus in vaccinated horses. Although the level and structure of genetic diversity were similar to those in naïve horses, intrahost bottlenecks may be more stringent in vaccinated animals, and mutations shared among horses often fall close to putative antigenic sites.
Ensuring equine biosecurity at London 2012.
The Veterinary record    February 5, 2013   Volume 172, Issue 5 117-119 doi: 10.1136/vr.f72
Slater J.The London 2012 Olympic and Paralympic Equestrian Games were the highest profile event in the 2012 equestrian calendar and were the culmination of four years of detailed and meticulous biosecurity planning to ensure that all horses arrived, competed and returned home safely and in good health. Josh Slater, Anthony Greenleaves and Andy Paterson describe how this was achieved.
Detection of equid herpesviruses 2 and 5 in a herd of 266 Lipizzaners in association with ocular findings.
Veterinary microbiology    February 4, 2013   Volume 164, Issue 1-2 139-144 doi: 10.1016/j.vetmic.2013.01.035
Rushton JO, Kolodziejek J, Tichy A, Nell B, Nowotny N.A herd of Lipizzaners (n=266) in three locations [Federal stud Piber (Styria), Heldenberg (Lower Austria) and the Spanish Riding School Vienna (Vienna)] were examined for ocular diseases and tested for herpesviruses (HVs) in PBMCs, nasal- and conjunctival swabs. In 167 (62.8%) horses equid herpesvirus-2 (EHV-2) nucleic acid was identified in at least one of the investigated samples, and 136 (51.1%) horses were positive for equid herpesvirus-5 (EHV-5) nucleic acid in at least one of the samples. One hundred and five (39.5%) of the horses mentioned above were identified with EHV-2/EHV-5 double i...
Lice infesting horses in three agroecological zones in central Oromia.
Journal of parasitic diseases : official organ of the Indian Society for Parasitology    February 3, 2013   Volume 38, Issue 4 352-357 doi: 10.1007/s12639-013-0235-3
Tafese A, Jibat T, Aklilu N, Zewdu H, Kumsa B.A cross-sectional study was conducted to determine the prevalence and species composition of lice infesting horses in three agroecological zones in seven different districts in central Oromia from November 2011 to April 2012. For this purpose, a total of 420 horses were thoroughly examined for presence of lice. Collected lice were identified to species level under a microscope. The study showed an overall prevalence of 28.8 % (121/420) lice infestation on horses. We identified two spp. of lice on horses namely, Bovicola (Werneckiella) equi and Haematopinus asini with an overall prevalence of ...
Report of the third Havemeyer workshop on infection control in equine populations.
Equine veterinary journal    February 2, 2013   Volume 45, Issue 2 131-136 doi: 10.1111/evj.12000
Morley PS, Anderson ME, Burgess BA, Aceto H, Bender JB, Clark C, Daniels JB, Davis MA, Hinchcliff KW, Johnson JR, McClure J, Perkins GA, Pusterla N....No abstract available
[Care for horses in the First World War].
Tijdschrift voor diergeneeskunde    February 2, 2013   Volume 138, Issue 1 40-41 
Carp J.No abstract available
Antimicrobial stewardship: Time for change.
Equine veterinary journal    February 2, 2013   Volume 45, Issue 2 127-129 doi: 10.1111/evj.12041
Bowen M.No abstract available
The history of arboviral infections of horses in Australia is being rewritten.
Australian veterinary journal    January 30, 2013   Volume 91, Issue 1-2 4 doi: 10.1111/avj.12030
Studdert MJ.No abstract available
The feral horse foot. Part B: radiographic, gross visual and histopathological parameters of foot health in 100 Australian feral horses.
Australian veterinary journal    January 30, 2013   Volume 91, Issue 1-2 23-30 doi: 10.1111/avj.12017
Hampson BA, de Laat MA, Mills PC, Walsh DM, Pollitt CC.It has been proposed that the feral horse foot is a benchmark model for foot health in horses. However, the foot health of feral horses has not been formally investigated. Objective: To investigate the foot health of Australian feral horses and determine if foot health is affected by environmental factors, such as substrate properties and distance travelled. Methods: Twenty adult feral horses from five populations (n = 100) were investigated. Populations were selected on the basis of substrate hardness and the amount of travel typical for the population. Feet were radiographed and photographed...
Prevalence, hematology, and treatment of balantidiasis among donkeys in and around Lahore, Pakistan.
Veterinary parasitology    January 30, 2013   Volume 196, Issue 1-2 203-205 doi: 10.1016/j.vetpar.2013.01.017
Khan A, Khan MS, Avais M, Ijaz M, Ali MM, Abbas T.The prevalence of Balantidium coli among donkeys in Lahore and adjoining areas was surveyed and a trial conducted to determine the efficacy of two antiprotozoal drugs: secnidazole (Dysen Forte) and Kalonji (Nigella sativa). Four-hundred donkeys were examined, and 73 (18.3%) were found positive for Balantidium coli. A slight decrease in PCV and an increase in Hb values of infected donkeys were found after antiprotozoal treatment. Secnidazole was 89.5% effective for the treatment of equine balantidiasis compared to 40.0% for Nigella sativa. This is the first report of balantidiasis in equines fr...