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Topic:Epidemiology

Epidemiology in horses involves the study of the distribution and determinants of health-related states and events in equine populations. It encompasses the investigation of patterns, causes, and effects of diseases and health conditions within horse populations. This field of study aims to identify risk factors for disease and targets for preventive healthcare. Key components of equine epidemiology include disease surveillance, outbreak investigation, and the study of disease dynamics within herds or regions. Research in this area often focuses on infectious diseases, zoonotic diseases, and the impact of environmental factors on equine health. This page compiles peer-reviewed research studies and scholarly articles that explore various aspects of epidemiology in horses, including disease prevalence, transmission pathways, and strategies for disease prevention and control.
Clinical and neuropathological features of West Nile virus equine encephalomyelitis in Italy.
Equine veterinary journal    February 8, 2000   Volume 32, Issue 1 31-35 doi: 10.2746/042516400777612080
Cantile C, Di Guardo G, Eleni C, Arispici M.West Nile (WN) virus infection is a mosquito-borne flavivirosis endemic in Africa and Asia. Clinical disease is usually rare and mild and only in a few cases the infection causes encephalomyelitis in horses, fever and meningoencephalitis in man. We report here the clinical and pathological findings in an epidemic of the disease involving 14 horses from Tuscany, Italy. All cases were observed from August to October 1998. Affected horses showed ataxia, weakness paresis of the hindlimbs and, in 6 cases, there was paraparesis progressing to tetraplegia and recumbency within 2 to 9 days. Eight anim...
Sweating and skin temperature responses of normal and anhidrotic horses to intravenous adrenaline.
Equine veterinary journal. Supplement    February 5, 2000   Issue 30 362-369 doi: 10.1111/j.2042-3306.1999.tb05249.x
Marlin DJ, Schroter RC, Scott CM, White S, Nyrop KA, Maykuth PL, Harris PA.Anhidrosis has been recognised for over half a century, but despite some excellent epidemiological studies, there has been little progress in understanding the aetiology of the condition. Using a modified ventilated capsule, we obtained dynamic, quantitative data on sweating responses in anhidrotic horses and normal sweating controls from the same environment. Ten horses with current seasonal anhidrosis and 10 matched normal sweating controls were selected. Each horse was given two 10 min infusions of 1 and 2 micrograms/kg/min adrenaline, separated by at least 6 h. Sweating responses and skin ...
Racing performance in red blood cell hypervolaemic standardbred trotters.
Equine veterinary journal. Supplement    February 5, 2000   Issue 30 617-620 doi: 10.1111/j.2042-3306.1999.tb05296.x
Persson SG, Osterberg I.The association between red blood cell hypervolaemia (RCHV) and racing performance was examined in 116 Standardbred trotters referred to the clinic during a 5 year period with histories of impaired racing performance. Red cell hypervolaemia was the only significant abnormality detected in a thorough clinical examination, cell volumes ranging 116-178% of the predicted normal values. They were also compared with the performance traits of the contemporary Swedish Standardbred trotter population (n = 58,058). The performance traits were based on earnings per year and start, best annual racing time...
Development of a PCR test for rapid diagnosis of contagious equine metritis.
The Journal of veterinary medical science    January 29, 2000   Volume 61, Issue 12 1287-1292 doi: 10.1292/jvms.61.1287
Anzai T, Eguchi M, Sekizaki T, Kamada M, Yamamoto K, Okuda T.In order to establish a rapid diagnostic method for contagious equine metritis (CEM), we developed and evaluated a polymerase chain reaction (PCR) test. Species-specific PCR primer sets were derived from the DNA sequence of a cloned DNA fragment of Taylorella equigenitalis that did not hybridize with the genome of a taxomonically related species, Oligella urethralis. Single step PCR with primer set P1-N2 and two-step semi-nested PCR with primer sets P1-N2 and P2-N2 detected as low as 100 and 10 CFU of the bacteria, respectively. Single-step PCR detected T. equigenitalis from genital swabs of e...
Multistate surveillance system in place for West Nile virus.
Journal of the American Veterinary Medical Association    January 19, 2000   Volume 216, Issue 1 11 
Nolen RS.No abstract available
[Validation of an indirect immunoenzyme assay for the detection of antibodies against Trypanosoma evansi in horses in Argentina].
Revue scientifique et technique (International Office of Epizootics)    January 11, 2000   Volume 19, Issue 3 810-818 
Monzón CM.An indirect enzyme-linked immunosorbent assay (ELISA) to detect antibodies against Trypanosoma evansi was evaluated using 90 different sera, obtained from naturally-infected horses. As negative controls, 218 sera from the T. evansi-free zone of Argentina, and 90 uninfected sera from the enzootic zone were used. The results of the ELISA were expressed in terms of percent positivity (PP) when compared with a positive primary reference serum, obtained from a horse experimentally-infected with T. evansi. The inter-assay coefficient of variation (CV), expressed as PP, was 44.7% for the negative con...
Role of dendritic cell targeting in Venezuelan equine encephalitis virus pathogenesis.
Journal of virology    January 7, 2000   Volume 74, Issue 2 914-922 doi: 10.1128/jvi.74.2.914-922.2000
MacDonald GH, Johnston RE.The initial steps of Venezuelan equine encephalitis virus (VEE) spread from inoculation in the skin to the draining lymph node have been characterized. By using green fluorescent protein and immunocytochemistry, dendritic cells in the draining lymph node were determined to be the primary target of VEE infection in the first 48 h following inoculation. VEE viral replicon particles, which can undergo only one round of infection, identified Langerhans cells to be the initial set of cells infected by VEE directly following inoculation. These cells are resident dendritic cells in the skin, which mi...
Epidemiologic analysis of factors influencing exertional rhabdomyolysis in Thoroughbreds.
American journal of veterinary research    January 6, 2000   Volume 60, Issue 12 1562-1566 
MacLeay JM, Sorum SA, Valberg SJ, Marsh WE, Sorum MD.To determine incidence, effect on performance, and management practices associated with exertional rhabdomyolysis (ER) in Thoroughbreds. Methods: Medical records for 984 Thoroughbreds and a survey of trainers of horses with and without ER. Methods: Medical records for 984 Thoroughbreds stabled at a midwestern racetrack were examined to determine the incidence of ER during the 1995 racing season. A retrospective questionnaire was administered to trainers to determine management practices associated with ER in 59 Thoroughbreds with ER and 47 control Thoroughbreds in training. Multiple logistic r...
Detection of trypanosome DNA in serologically positive but aparasitaemic horses suspected of dourine in Ethiopia.
The Tokai journal of experimental and clinical medicine    January 6, 2000   Volume 23, Issue 6 303-308 
Clausen PH, Gebreselassie G, Abditcho S, Mehlitz D, Staak C.A field study of horses was conducted in the province of Bale, Ethiopian highlands. A rapid questionnaire analysis indicated that dourine, known as "Dirressa", is a major health problem of equines in this area. A total of 121 horses suspected of dourine were examined by use of clinical, parasitological, serological and DNA based techniques. Incoordination of hindlegs (76%), swelling of external genitalia (48.8%) and emaciation (39.7%) were the most common clinical signs observed. Using the haematocrit centrifugation technique (HCT), no trypanosomes were detected in blood, genital washes or tis...
‘Cross-protection’ and ‘cross-reaction’ with equine influenza vaccines.
The Veterinary record    January 5, 2000   Volume 145, Issue 22 647 
Newton JR, Wood JL, Jessett D, Yates PJ, Mumford JA.No abstract available
Proceedings of the Seventh International Symposium on Equine Reproduction, July 12-17, 1998, Pretoria, South Africa.
Journal of reproduction and fertility. Supplement    January 1, 2000   Issue 56 3-734 
No abstract available
Equine viral arteritis: further characterization of the carrier state in stallions.
Journal of reproduction and fertility. Supplement    January 1, 2000   Issue 56 3-11 
Timoney PJ, McCollum WH.Further characterization of the carrier state in stallions infected with equine arteritis virus revealed that there is considerable variation in the frequency of its occurrence among breeds. The frequency ranged from 12.5% (Holsteiner stallions) to 72.7% (Dutch Warmblood stallions), with a mean occurrence of 40.8% in the seropositive stallions (n=561) examined. More than 70% of the virus shedders were Standardbred stallions. The carrier state was not confirmed in any of the stallions that had been vaccinated against equine viral arteritis nor was there any evidence of intermittent virus sheddi...
Rabies surveillance in the United States during 1998.
Journal of the American Veterinary Medical Association    December 29, 1999   Volume 215, Issue 12 1786-1798 
Krebs JW, Smith JS, Rupprecht CE, Childs JE.During 1998, 49 states, the District of Columbia, and Puerto Rico reported 7,961 cases of rabies in nonhuman animals and 1 case in a human being to the Centers for Disease Control and Prevention, a decrease of 6.5% from 8,509 cases in nonhuman animals and 4 cases in human beings reported in 1997. More than 92% (7,358 cases) were in wild animals, whereas > 7.5% (603 cases) were in domestic species (compared with 93% in wild animals and 7% in domestic species in 1997). Decreases were evident in all of the major contributing species groups, with the exception of skunks and bats. The relative cont...
Toward the incrimination of epidemic vectors of eastern equine encephalomyelitis virus in Massachusetts: abundance of mosquito populations at epidemic foci.
Journal of the American Mosquito Control Association    December 28, 1999   Volume 15, Issue 4 479-492 
Moncayo AC, Edman JD.Putative epidemic/epizootic eastern equine encephalomyelitis virus (EEE) vector populations were compared at 15 recent (1982-90) human and horse case sites in Bristol and Plymouth counties in southeastern Massachusetts. Carbon dioxide-baited American Biophysics Corporation light traps were used for trapping adult mosquitoes to estimate biting risk in these foci of known transmission. Population data suggest that Coquillettidia perturbans, Aedes canadensis, and Culex salinarius are more likely vectors of EEE in Massachusetts than Aedes vexans, Anopheles punctipennis, and Anopheles quadrimaculat...
Prevalence of antibodies to Neospora sp. in horses from Alabama and characterisation of an isolate recovered from a naturally infected horse [corrected].
International journal for parasitology    December 23, 1999   Volume 29, Issue 10 1537-1543 doi: 10.1016/s0020-7519(99)00140-x
Cheadle MA, Lindsay DS, Rowe S, Dykstra CC, Williams MA, Spencer JA, Toivio-Kinnucan MA, Lenz SD, Newton JC, Rolsma MD, Blagburn BL.An IFAT was used to determine the prevalence of Neospora-specific IgG antibodies in serum from Alabama horses. Serum samples (n = 536) were from asymptomatic horses routinely submitted for equine infectious anaemia virus infection testing. We also subjected a 13-year-old horse with CNS disease to necropsy examination for isolation and in vitro cultivation of protozoal organisms. In antemortem tests, this horse was positive for antibodies to Neospora sp. in the IFAT and western immunoblot. Results of the prevalence survey indicated that IgG antibodies to Neospora were present in 62 (11.5%) of t...
Survey on equine cryptosporidiosis in Poland and the possibility of zoonotic transmission.
Annals of agricultural and environmental medicine : AAEM    December 23, 1999   Volume 6, Issue 2 161-165 
Majewska AC, Werner A, Sulima P, Luty T.The present study was undertaken to investigate the prevalence of Cryptosporidium infection in horses used for recreational riding as well as in humans. A total of 106 faecal specimens from horses raised in 4 localities of western Poland and 6 stool samples from 3 persons who had constant or sporadic contact with horses were screened microscopically for oocysts using modified Ziehl-Neelsen staining. Enzyme immunoassay (EIA) was additionally used for the detection of coproantigen in human stool samples as well as in 43 randomly selected horse faecal samples. The overall infection rate of horses...
Equine dysautonomia: has grass been blamed unfairly all this time?
Equine veterinary journal    December 22, 1999   Volume 31, Issue 6 451-452 doi: 10.1111/j.2042-3306.1999.tb03849.x
Wood JL, McGorum BC, Mayhew IG.No abstract available
Biological control of parasitic nematodes of the horse; the need, practicalities and prospects.
Equine veterinary journal    December 22, 1999   Volume 31, Issue 6 449-450 doi: 10.1111/j.2042-3306.1999.tb03848.x
Waller PJ.No abstract available
Post-mortem findings of gastric ulcers in Swedish horses up to one year of age: a retrospective study 1924-1996.
Acta veterinaria Scandinavica    December 22, 1999   Volume 40, Issue 2 109-120 doi: 10.1186/BF03547028
Sandin A, Skidell J, Häggström J, Girma K, Nilsson G.Necropsy records from 702 horses, less than one year old, that were subjected to necropsy between 1924 and 1996 were used to estimate the prevalence of gastric ulceration in younger horses and to evaluate some potential risk factors that may contribute to the development of gastric ulceration. Information concerning breed, gender, age, season of death, clinical signs of colic, medical treatment, parasitism and documentation of diseases in different organs were recorded, as well as size, number and anatomical distribution of ulcers. Gastric ulcers were found in 96 of 702 young horses (14%) and ...
A survey of white line disease in Japanese racehorses.
Equine veterinary journal    December 22, 1999   Volume 31, Issue 6 515-518 doi: 10.1111/j.2042-3306.1999.tb03861.x
Kuwano A, Tanaka K, Kawabata M, Ooi Y, Takahashi T, Yoshihara T, Reilly JD.A survey was carried out into white line disease in 1781 Thoroughbred racehorses kept in stables at the Japan Racing Association (JRA) Miho Training Center (MTC) September-October 1996. The survey was conducted while horses were being shod by farriers. The horses that still exhibited damaged white lines after regular trimming were diagnosed as having white line disease. The factors recorded were age, sex, number of diseased horses, number of diseased hooves, number of lesions by region over the bearing border of the hoof and the classified length of such lesions. The percentage of total diseas...
The association of Clostridium botulinum type C with equine grass sickness: a toxicoinfection?
Equine veterinary journal    December 22, 1999   Volume 31, Issue 6 492-499 doi: 10.1111/j.2042-3306.1999.tb03857.x
Hunter LC, Miller JK, Poxton IR.The cause of grass sickness, an equine dysautonomia, is unknown. The disease usually results in death. Gastrointestinal (GI) dysfunction is a common clinical manifestation in all forms of the disease. It is generally thought that equine grass sickness (EGS) is caused by an ingested or enterically produced neurotoxin which is absorbed through the GI tract. Clostridium botulinum was first implicated as a causative agent when it was isolated from the GI tract of a horse with EGS in 1919. The aim of the present study was to investigate the hypothesis that EGS results from toxicoinfection with C. b...
A serological and clinical follow-up in horses with confirmed equine granulocytic ehrlichiosis.
Equine veterinary journal    December 22, 1999   Volume 31, Issue 6 473-477 doi: 10.1111/j.2042-3306.1999.tb03853.x
Artursson K, Gunnarsson A, Wikström UB, Engvall EO.For diagnosis of equine granulocytic ehrlichiosis (EGE) serological testing of antibodies to Ehrlichia equi is frequently used. An elevated antibody level is often misinterpreted as confirmative of active infection and results in treatment with antibiotics. If only seropositivity is considered as the diagnostic criterium, many horses showing convalescence titres will be treated. This study was undertaken to obtain information about the kinetics of antibodies during the course of infection and, for this purpose, 45 horses with clinical signs of EGE and confirmed ehrlichiaemia were monitored ser...
Management factors affecting the risk for vesicular stomatitis in livestock operations in the western United States.
Journal of the American Veterinary Medical Association    December 20, 1999   Volume 215, Issue 9 1263-1268 
Hurd HS, McCluskey BJ, Mumford EL.To identify management factors affecting the risk of animals developing vesicular stomatitis (VS). Methods: Case-control study. Methods: Horses, cattle, and sheep with suspected vesicular stomatitis on 395 premises in Colorado, New Mexico, Utah, and Arizona. Methods: Data were collected during the VS outbreak of 1997. Diagnosticians interviewed livestock owners and completed a supplemental questionnaire. Cases were defined as those premises that had a completed questionnaire and had > or = 1 animal positive for VS. Control premises were all premises investigated that had a completed questionna...
Review of the 1997 outbreak of vesicular stomatitis in the western United States.
Journal of the American Veterinary Medical Association    December 20, 1999   Volume 215, Issue 9 1259-1262 
McCluskey BJ, Hurd HS, Mumford EL.No abstract available
Prevalence of stereotypic and other problem behaviours in thoroughbred horses.
Australian veterinary journal    December 11, 1999   Volume 77, Issue 10 678-679 doi: 10.1111/j.1751-0813.1999.tb13166.x
Pell SM, McGreevy PD.No abstract available
Epizootic lymphangitis in horses: a review of the literature.
Revue scientifique et technique (International Office of Epizootics)    December 10, 1999   Volume 18, Issue 3 691-699 
al-Ani FK.Epizootic lymphangitis is a relatively common infectious disease of horses and other liquids in certain parts of the world. The infection rate varies according to the geographic area and the age of the animal. The disease is most commonly characterised by a cord-like appearance of the subcutaneous lymphatic and cutaneous pyogranulomas, the discharge from which contains spherical or pear-shaped bodies of the causal agent, Histoplasma farciminosum. Diagnosis can be made by the demonstration of typical organisms in stained smears, culture and tissue sections. Serological tests and a skin hypersen...
Veterinarians key to discovering outbreak of exotic encephalitis.
Journal of the American Veterinary Medical Association    December 1, 1999   Volume 215, Issue 10 1415-1419 
Nolen RS.No abstract available
African horse sickness in Portugal: a successful eradication programme.
Epidemiology and infection    December 1, 1999   Volume 123, Issue 2 337-346 doi: 10.1017/s0950268899002897
Portas M, Boinas FS, Oliveira E Sousa J, Rawlings P.African horse sickness (AHS) was diagnosed for the first time in southern Portugal in autumn 1989, following outbreaks in Spain. AHS virus presence was confirmed by virus isolation and serotyping. An eradication campaign with four sanitary zones was set up by Central Veterinary Services in close collaboration with private organizations. Vaccination began on 6 October. In February 1990, vaccination was extended to all Portuguese equines (170000 animals). There were 137 outbreaks on 104 farms: 206 of the equidae present died (16%) or were slaughtered (14%); 81.5% were horses, 10.7% were donkeys ...
Prevalence of antibodies to Neospora caninum in horses in North America.
The Journal of parasitology    November 30, 1999   Volume 85, Issue 5 968-969 
Dubey JP, Romand S, Thulliez P, Kwok OC, Shen SK, Gamble HR.Serum samples from 296 horses slaughtered for food in the United States were tested for antibodies to Neospora caninum by the Neospora-agglutination test (NAT). Antibodies were found in 69 (23.3%) horses with titers of 1:40 (19 horses), 1:80 (19 horses), 1:100 (3 horses), 1:200 (7 horses), 1:400 (4 horses), and 1:800 (17 horses). This is the first serologic survey for N. caninum antibodies in horses.
Simplified technique for isolation, excystation, and culture of Sarcocystis species from opossums.
The Journal of parasitology    November 30, 1999   Volume 85, Issue 5 979-981 
Murphy AJ, Mansfield LS.Sarcocystis neurona is a protozoan parasite that causes a neurological disease in horses called equine protozoal myeloencephalitis. The route of transmission is speculated to be by fecal-oral transfer of sporocysts shed from opossums. Controversy exists regarding both the natural life cycle for this parasite as well as the species identity of opossum Sarcocystis. To provide stage-specific material for species comparison, 27 opossums from southern Michigan were screened for Sarcocystis spp. sporocysts. Seven opossums were positive for Sarcocystis sporocysts by fecal flotation. A simplified, eff...