Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Rapp HJ, Jost H, Stechele M, Becker M.A report is given of obstructive ectasy of both kidneys in a newborn foal. Diagnosis and therapy are described as well as differential diagnosis.
Church S.Three Quarter Horse stallions and 5 of their 11 tested progeny were diagnosed as affected with the inherited autosomal dominant defect hyperkalaemic periodic paralysis in Victoria in 1992. The diagnoses were based on the appearance of clinical signs and associated increased plasma potassium concentrations in response to oral potassium loading. All affected horses were descendants of the American Quarter Horse Impressive. Indirect evidence indicates that at least 3 other affected Quarter Horse stallions have stood or are standing at stud in Australia. The clinical details of the affected horses...
Chirnside ED, de Vries AA, Mumford JA, Rottier PJ.Complementary DNAs encoding ORFs 2 to 7 equine arteritis virus (EAV) have been cloned into the expression vector pGEX to produce glutathione-S-transferase fusion proteins. Recombinant proteins were affinity purified and screened in ELISA with equine sera to identify immunoreactive polypeptides. The large envelope glycoprotein (GL) was identified as the most reactive to EAV-positive equine sera and an immuno-dominant epitope was mapped between amino acids 55 and 98 by subcloning and expression. A fusion protein covering this region and a GL-specific synthetic peptide (residues 75 through 97) in...
Bacigalupo MA, Ius A, Meroni G, Dovis M, Petruzzelli E.A time-resolved fluoroimmunoassay (TR-FIA) for the direct determination of clenbuterol residues in horse urine using a highly specific monoclonal antibody has been compared with an immunoenzymometric assay (IEMA). The sensitivity of both methods was 10 pg; the calibration curve was linear between 10 and 10(5) pg for the TR-FIA and between 10 and 10(4) pg for the IEMA.
Silvia PJ, Meyer SL, Fitzgerald BP.Twelve horse mares were used in a repeated-measures design consisting of 3 replicates of 4 mares each. On Day 6 following ovulation, luteolysis was initiated with an i.m. injection of prostaglandin F2 alpha (PGF2 alpha; Lutalyse, 10 mg). Either 12 (-12) or 36 (-36) h before PGF2 alpha (PRE), blood samples were collected simultaneously from the intercavernous sinus (ICS) and jugular (JUG) vein at 10-min intervals for an 8-h period. Pituitary capacity to exogenous GnRH (2 micrograms/kg BW, i.v.) was evaluated at the alternate time point within this period. Frequent sampling and GnRH challenge we...
Ruffin DC, Schumacher J, Comer JS.A mare at 126 days of gestation was examined because of signs of abdominal pain. The cause of abdominal pain could not be determined by physical examination. Lack of response to analgesics and small intestinal distention on palpation per rectum prompted exploratory celiotomy. Small intestine was found to be entrapped by the uterus, which had undergone torsion. The uterus was returned to its correct position, and the small intestine was decompressed. After surgery, the mare was treated with orally administered progestin to prevent abortion. The mare recovered and delivered a live foal at 354 da...
Dyson SJ, Denoix JM.The palmar (plantar) aspect of the pastern is an anatomically complex area and an understanding of this is a prerequisite for accurate diagnosis of injuries in this area. The gross and normal ultrasonographic anatomy are described, and injuries of the superficial and deep digital flexor tendons and the digital flexor tendon sheath, the distal sesamoidean ligaments, and the palmar ligaments of the proximal interphalangeal joint are discussed.
Wakuri H, Mutoh K, Ichikawa H, Liu B.We have observed and re-evaluated the histology of the skin of the horse, using samples from four Thoroughbreds. The skin was composed of the usual three components: epidermis, dermis and subcutis. In particular, the dermis was found to have three fibrous components: a papillary layer, a reticular layer and a cordovan-leather tissue layer. The cordovan-leather tissue layer was subdivided into a superficial main layer and a deeper accessory layer. The superficial main layer was thick, and present in all of the skin samples. The deeper accessory layer was found in the dorsal and dorso-lateral pa...
Meyer H, Radicke S, Kienzle E, Wilke S, Kleffken D, Illenseer M.In this study preileal starch digestibility of starchy feeds (oats, corn, barley, potatoes, manioc) was determined in seven jejunofistulated horses. The grains were fed whole (oats, corn), rolled (oats, barley), crushed, ground and expanded (corn); the potatoes were fresh, the manioc rolled. Ground corn was also fed in combination with amylase. The feeds were fed partly isolated or in combination with alfalfa meal or hay (Table 1). At least four horses with a cannula in the terminal jejunum were used for each diet. Two meals per day were offered at 12 h intervals. The starch intake was mostly ...
Dyson SJ, Dik KJ.The use of diagnostic ultrasonography has greatly enhances our ability to diagnose injuries of tendons and tendon sheaths that were previously either unrecognized or poorly understood. For may of these injuries, there is currently only a small amount of follow-up data. This article considers injuries of the deep digital flexor tendon and its accessory ligament, the carpal tunnel syndrome soft tissue swellings on the dorsal aspect of the carpus, intertubercular (bicipital) bursitis and bicipital tendinitis, injuries of the gastrocnemius tendon, common calcaneal tendinitis, rupture of peroneus (...
Dyson SJ, Arthur RM, Palmer SE, Richardson D.The gross and functional anatomy of the suspensory ligament (SL) and its ultrasonographic variability are described. Injuries of the suspensory apparatus are divided into lesions confined to the proximal one third of the metacarpus or metatarsus (proximal suspensory desmitis and avulsion fractures), lesions of the body, and branch lesions. Complete breakdown injuries are also discussed. In view of the close association of the SL, the second, third, and fourth metacarpal or metatarsal bones, and the proximal sesamoid bones, associated bony lesions are also considered.
Lunn DP, Holmes MA, Schram B, Duffus WP.Equine immunoglobulin G is currently classified as consisting of five sub-isotypes: IgGa, b, and c, IgG(T), and IgG(B). The study of the role of these immunoglobulins in antigen-specific responses, and the examination of their functional properties would be greatly facilitated by the availability of monoclonal antibodies (Mabs) that distinguish between them. The production and characterization of two Mabs that recognize an IgG sub-isotype with the characteristics of IgG(ab) is described. The immunoglobulin identified by these Mabs had a heavy chain weight of 53 kDa, was of rapid cathodal elect...
Guerin MV, Deed JR, Kennaway DJ, Matthews CD.Plasma melatonin was measured at the winter and summer solstices and the autumn and spring equinoxes in four mares held under natural conditions at 35 degrees S. At all seasons the onset of the nightly elevated melatonin was coincident with or after the time of sunset and the melatonin offset after the time of sunrise. The duration of elevated melatonin was not different from the duration of natural scotophase for each season, with the duration of elevated melatonin longer in winter than the other seasons. Immediately following each 24 hr sampling two mares were resampled in acutely extended d...
McCann ME, Watson TD, Boudinot FD, Moore JN.We evaluated the pharmacokinetics of IV administered sodium heparin and the pharmacodynamic effect of heparin on lipoprotein lipase (LPL) activity. Horses were allotted to 3 groups. Plasma samples were obtained from each horse before and at various times for 6 hours after heparin administration for determination of heparin concentration, LPL activity, and activated partial thromboplastin time (APTT). The disposition of heparin was dose dependent. The area under the plasma heparin concentration vs time curve (AUC) increased more than proportionally with dose, indicating that heparin elimination...
Kanaly ST, Hines SA, Palmer GH.Rhodococcus equi, a facultative intracellular bacterium, causes chronic, often fatal granulomatous pneumonia in young horses and in humans with AIDS. The inability of host alveolar macrophages to kill intracellular R. equi results in the development of granulomas and progressive loss of pulmonary parenchyma. Clearance of the organism from the lung requires functional CD4+ T cells. The purpose of this study was to identify the cytokine effector mechanisms that mediate clearance of R. equi from the lung. Mice were treated with monoclonal antibodies (MAbs) to either gamma interferon (IFN-gamma) o...
Richardson JD, Cripps PJ, Lane JG.Dental features are commonly expected to provide an accurate estimate of a horse's age. In this study the dentition of 434 thoroughbreds was photographed and the individual dental features documented, the true age of all the horses was known. For each dental feature the correlation with true age was determined. The eruption of the incisor teeth was the most consistent feature but it was not totally reliable. The presence of a hook on the upper corner incisor and Galvayne's groove proved to be of no value when estimating age and, of the attritional features studied, the dental star showed the h...
Chopineau M, Stewart F, Allen WR.The coding regions of the horse (Equus caballus) and donkey (E. asinus) luteinizing hormone (LH) beta-subunit transcripts were cloned from pituitary gland RNA, in order to investigate their relationships to the corresponding equine chorionic gonadotropin (CG) beta-subunits and to further understand the unusual receptor-binding properties of equine LH and CG. The horse and donkey LH beta-subunit sequences were very similar (97% identity at the nucleotide (nt) level; 93% at the amino acid (aa) level), confirming their very close evolutionary linkage and also indicating that the C-terminal extens...
Richardson JD, Cripps PJ, Hillyer MH, O'Brien JK, Pinsent PJ, Lane JG.There is a widely held belief that a horse can be accurately aged by an examination of its teeth but this belief has recently been questioned. In this study photographs were taken of the dentition of 434 thoroughbreds of known age. Four experienced equine clinicians provided estimates of the ages of the horses from the photographs. A comparison of the estimated and true ages showed large discrepancies in many cases and the discrepancies increased as the horse's true age increased. The results show that the ageing of horses from their dentition is an imprecise science. It is suggested that writ...
Montesso F, Wright IM.Clinical and radiographic examinations of three horses with histories of trauma and/or wounds to the stifle revealed chip fractures from the medial trochlear ridge of the femur of one of them and from the lateral ridges of the femurs of the others. The joints were evaluated and the fragments of bone were removed by arthroscopy. The results were good in all three horses.
Campbell-Beggs CL, Johnson PJ, Wilson DA, Miller MA.A 12-hour-old female standardbred foal developed signs of abdominal pain, tachycardia, tachypnoea and fever associated with chylous ascites. Small intestinal obstruction was due to segmental, mid-jejunal lymphangiectasia. Post mortem examination revealed a lack of communication between afferent and efferent lymphatic vessels in the mesenteric lymphocentre, a defect which was suspected to be congenital.
Dillon AM, Heath MF.The effects of the protein tyrosine kinase inhibitors tyrphostins B42 and B46 on equine platelet function and protein tyrosine phosphorylation (PTP) were assessed. Tyrphostins B42 and B46 (both at 100 microM concentration) produced significant inhibition of thrombin-stimulated equine platelet aggregation. The effect of tyrphostin B46 was also time-dependent. The same concentration of these inhibitors produced very little or no inhibition of platelet-activating factor (PAF)-induced aggregation. The effects of tyrphostins B42 and B46 on thrombin- and PAF-stimulated PTP were generally similar, al...
Campagnolo ER, Trock SC, Hungerford LL, Shumaker TJ, Teclaw R, Miller RB, Nelson HA, Ross F, Reynolds DJ.Dermatitis consisting of blisters on the nose and other parts of the body was reported among horses at a Midwestern horse show. Some horses also had jaundice, hematuria and anorexia. An outbreak investigation was initiated, and of 239 horses for which information could be obtained, 58 (24%) were found to have been affected. Median duration of illness was 5 days, and all horses recovered. Age, sex, water source, grain source, and stabling location were not associated with illness. The use of wood shavings bedding obtained at the show grounds was the factor most strongly associated with the deve...
Gliatto JM, Alroy J.A horse with malignant lymphoma (histiolymphocytic) and cutaneous amyloidosis is described. The lymphoma involved the dura mater of the spinal cord and some of the peripheral lymph nodes. Multifocal amyloid deposits were present in the skin and subcutis of the ventral abdomen but not within the lymphoma cell infiltrates or in the viscera.
Moore BR, Weisbrode SE, Biller DS, Williams J.A 19-year-old Appaloosa gelding was reluctant to move. Radiography revealed diffuse, permeative lysis of the cortex and subchondral bone of the phalanges, third metacarpal bones, proximal sesamoid bones, radius, carpal bones, tibia, mandible, and nasal bones of the skull. A comminuted fracture of the distal aspect of the left third metacarpal bone was identified on a lateral to medial radiographic view of the left metacarpophalangeal joint. Histologic examination of the first phalanx, third metacarpal bone, and sternum revealed multifocal infiltrates of nodular lymphosarcoma in cortical and su...
Steagall WK, Robek MD, Perry ST, Fuller FJ, Payne SL.The retrovirus equine infectious anemia virus (EIAV) encodes a dUTPase situated between reverse transcriptase and integrase. We have described the inability of EIAV with a 270-bp dUTPase deletion, delta DU EIAV, to replicate to wild-type (WT) levels in equine macrophages (D. S. Threadgill, W. K. Steagall, M. T. Flaherty, F. J. Fuller, S. T. Perry, K. E. Rushlow, S. F. J. LeGrice, and S. L. Payne, J. Virol. 67, 2592-2600, 1993). Here we describe the construction of a second dUTPase-deficient virus (DUD71E) containing a single amino acid substitution in dUTPase. delta DU and DUD71E replicate to ...
McGreevy PD, French NP, Nicol CJ.The behaviour of horses competing in different disciplines was studied and the relationship between the time they spent out of the stable and the prevalence of abnormal behaviour was examined. The owners of dressage, eventing and endurance horses were sent a questionnaire and a total of 1101 responses were received, giving data on 1750 horses. The behaviours studied were wood-chewing, weaving, crib-biting/wind-sucking and box-walking. The reported percentage prevalences of abnormal behaviour for the dressage, eventing and endurance horses were 32.5, 30.8 and 19.5, respectively. The relationshi...
Faramarzi B, Nelson S, Dong F.Imbalances and altered kinetics of the hoof result in lameness in horses. Previously, studies have focused on the midstance phase of a gait, hence, available information on the impact phase is scarce. This study aimed to investigate the effect of hoof trimming on the fore and hindhooves at the impact phase of the walk. Our objective was to compare the kinetic variables of force (N), contact area (cm), contact pressure (kPa), and peak contact pressure (kPa) before and after hoof trimming. Nine Arabian horses were walked straight over a pressure plate to collect the above kinetic variables for b...
Abu-Halaweh M, Abo-Shehada MN, Khalil R.A cross-sectional study was carried out on a sample of 379 horses to determine the seroprevalence of Neospora spp. in Jordan using the indirect fluorescent antibody test. Five variables, namely locality (n=10), climatic zone (n=4), age group (n=3), gender, and breed were tested as risk factors for Neospora-immunoglobulin (Ig)G seropositivity at four cutoff titers (1:50, 1:200, 1:400, and 1:800) using univariate and multivariate logistic regression analyses. A total of 122 (32%; 95% CI: 28, 37) sera samples had anti-Neospora-IgG at a cutoff titer of 1:50. Increased Neospora-IgG seropositivity w...
Wong DM, Davis JL, Alcott CJ, Hepworth-Warren KL, Galow-Kersh NL, Rice S, Coetzee JF.The objective of this study was to evaluate the pharmacokinetic properties and physiologic effects of a single oral dose of alprazolam in horses. Seven adult female horses received an oral administration of alprazolam at a dosage of 0.04 mg/kg body weight. Blood samples were collected at various time points and assayed for alprazolam and its metabolite, α-hydroxyalprazolam, using liquid chromatography/mass spectrometry. Pharmacokinetic disposition of alprazolam was analyzed by a one-compartmental approach. Mean plasma pharmacokinetic parameters (±SD) following single-dose administration of ...
Schönfelder AM, Sobiraj A.To describe the use of a vaginal mucosal pedicle flap for repair of rectovaginal fistulae (RVF) in mares. Methods: Clinical case report. Methods: Three mares with RVF. Methods: After debriding the RVF, a dorsally based U-shaped mucosal and submucosal pedicle flap (2-4 mm thick) was dissected from the vaginal wall, rotated approximately 90 degrees angle to close the ventral aspect of the fistula and sutured in position with 10-13 single sutures that did not penetrate the rectal mucosa. This positioned the vaginal mucosa so that it was continuous with the rectal mucosa. Results: Two RVF healed b...
McKeever KH.An increasing percentage of the equine population is more than 15 years old, many performing various athletic activities into their 20s. Studies of aged humans have led to a fine tuning of exercise prescription to promote fitness while preventing adverse and potentially dangerous effects of excessive exercise. However, limited data exist regarding the exercise capacity of aged horses. This article presents an overview of published studies on aging-induced decreases in physiologic function and exercise capacity in the horse. The information presented can be used as a guide for exercise prescrip...
Olitsky PK, Long PH.The virus of vesicular stomatitis is not readily killed by formalin. This chemical is one of a group which coagulates the proteins of the medium in which the virus is usually contained. It has already been found(7) that other reagents of the protein-coagulating group are not actively virucidal) and the effect of formalin in this instance is therefore characteristic of the group. The so called formalinized vaccines which give rise to immunity can be shown to have done so because of the presence of living virus. A single injection of such so called "vaccine," or of other material containing livi...
Hurlimann J, Darling H.The synthesis of immunoglobulins by the salivary glands from eight different species was studied. It has been demonstrated that salivary glands from the cow, horse, sheep, pig, rat and guinea-pig preferentially synthesize a fast migrating immunoglobulin which seems to be analogous to IgA. In three of the species, the cow, sheep and pig, the IgA-like component cross-reacts with human IgA. The IgA synthesized by the salivary glands from the rat cross-reacts with the mouse IgA. When one compares the salivary IgA from the cow, horse, sheep, pig and rat with the IgA synthesized by the lymph nodes,...
Alexander GR, Gibson KT, Day RE, Robertson ID.To measure the effects of transection of the accessory ligament of the superficial digital flexor (SDF) muscle (superior check desmotomy) on flexor tendon and suspensory ligament (SL) strain in vitro. Methods: In vitro experimental biomechanical investigation. ANIMALS USED: Ten equine cadaver forelimbs. Methods: The effects of superior check desmotomy were determined using equine cadaver forelimbs secured in a servocontrolled hydraulic testing machine. Strain sensors were used to measure strain on the superficial and deep digital flexor tendons and SL, and a goniometer was used to measure join...
Enbergs H, Karp HP, Schönherr U.The present study was aimed to determine the contents of calcium, inorganic phosphate, parathormon, 25-OH-D3 and the activity of alkaline phosphatase in the plasma of one- and two-years-old thoroughbred horses. Data were obtained monthly from 44 one-year-old thoroughbred of 4 different studs from May during grazing-season and from October during stable-, resp. training-season up to april of the following year. Calcium, inorganic phosphate and the activity of alkaline phosphatase were measured with a photometric method and the concentration of PTH and 25-OH-D3 were determined with a radioimmuno...
Barber SM.The horse, a flight animal that is used extensively by man, frequently receives injuries to its neck or head that result mostly from its management and handling. Better facilities, training of the horse, and horsemanship skills of the handler could prevent many of these injuries. Because many body systems can be involved, with potentially major consequences regarding health, performance, and appearance, early recognition of trauma and competent treatment are crucial. Progress has been made in the treatment of some tracheal and esophageal injuries. Severe tracheal trauma and rupture of the esop...
Sengupta PP, Rudramurthy GR, Ligi M, Jacob SS, Rahman H, Roy P.Trypanosoma evansi, a haemoflagellated protozoan parasite, is responsible for chronic as well as the acute debilitating disease called surra in a wide range of herbivores and carnivores including domestic and wild animals. Since the parasite is having wide host range, there is a need for diagnostic test which can detect the T. evansi specific antibody in different species of animals for generating sero-surveillance data. In the present study we developed and evaluated competitive enzyme immunoassay using monoclonal antibodies (MAbs) raised against recombinant variable surface glycoprotein (rVS...
Hirsh DC, Kirkham C, Wilson WD.Fifteen isolates of Escherichia coli obtained from the blood and tissues of septic foals had plasmid DNA of size ranging from 2.5 to 93 megadaltons. These isolates grew in normal equine serum (serum resistant), a trait previously documented to be expressed by isolates obtained from blood and tissues of septic foals, but not by isolates obtained from the feces of clinically normal horses. Of these isolates, 3 contained conjugal plasmids that encoded resistance to multiple antimicrobial agents linked to serum resistance and, in 1 isolate, to production of aerobactin as well. Serum resistance and...
Stoneham SJ, Digby NJ, Ricketts SW.The importance of colostrum for the passive transfer of maternal immunity to foals is well recognised. This survey reports the incidence of the failure of passive transfer of colostral immunity in thoroughbred foals in the United Kingdom during 1988 to 1990, and the effect of plasma transfusions on IgG levels in a group of them. The incidence of disease in these foals first month of life is also recorded.
Wooden GR, Crane CS, Beisel CG.The objective of this study was to determine the effect of Hesperidin Complex and Lemon Bioflavonoid Complex (HC/LBC) on the growth and development of thoroughbred horses. The trial involved twenty-four foals (12 colts, 12 fillies) allotted to treatment shortly after weaning. The study was conducted for a 342-d growing phase and a 153-d training phase, or a total of 495-d. The HC/LBC was included in the test diet at a level calculated to supply the compound at 55 mg X kg body weight-1 X d-1. During the growing phase, average daily gain of colts that received HC/LBC was higher (P less than .05)...
Bernard WV, LeBlanc MM, Webb BA, Stromberg AJ.To determine whether gavage of pregnant mares (housed without access to pasture) with starved eastern tent caterpillars (ETCs) or their excreta is associated with early fetal loss (EFL), panophthalmitis, or pericarditis. Methods: Randomized clinical trial. Methods: 15 mares. Methods: 15 mares with fetuses from 40 to 80 days of gestation (dGa) were randomly assigned to 1 of 3 groups and received 2.5 g of ETC excreta, 50 g of starved ETCs, or 500 mL of water, respectively, once daily for 10 days. Mares were housed in box stalls, walked twice daily, and not allowed access to pasture for 12 days b...
Waterman AE, Amin A.The plasma concentration of pethidine was measured in 16 horses, after its administration intravenously (i.v.) at a dose rate of 1 mg/kg bodyweight (bwt). In eight animals studied before surgery, the plasma levels of the drug decreased in a bi-exponential manner with a distributive half life of 3 mins and an elimination half life of 57.7 mins. Total body clearance was 17.7 ml/kg bwt/min. The remaining horses were investigated immediately after a period of anaesthesia and surgery and in these animals the drug exhibited smaller volumes of distribution (V1 cand Vdarea) and a significantly lower c...
Lees P, Higgins AJ, Mawhinney IC, Reid DS.The absorption pattern of phenylbutazone was studied in five horses during administration of the drug in a paste formulation on days 1, 5, 8 and 12 of a 12-day dosing schedule. Since two or more plasma concentration peaks were usually obtained following each oral dose, it was concluded that phasic absorption was a particular feature of the oil:water formulation of the product. Possible causes of this unusual absorption pattern are discussed and the therapeutic implications of both phasic absorption and the recorded values of Cmax, tmax and AUC024 for phenylbutazone and its active metabolite ox...
Davis LE.Adverse drug reactions occasionally occur in the horse. The majority can be anticipated and avoided. The practicing veterinarian should understand the various types of adverse reactions as well as their mechanisms so that should such a reaction occur, the practitioner can promptly recognize the problem and institute corrective measures.
Nelson R, Hampe DW.Tracheal mucous transport rates were measured in 12 nonanesthetized horses after an intratracheal injection of 99mtechnetium-sulfur colloid. The transport rate of the subsequent bolus of radioactivity was determined, using a portable scaler rate meter fitted with a high-energy gamma-scintillation probe. A gamma-scintillation camera was used to verify bolus form and movement in 1 horse. The mean tracheal mucous transport rate was 1.66 +/- 0.24 cm/min.
Foreman JH, Grubb TL, Benson GJ, Frey LP, Foglia RA, Griffin RL.This study was designed to characterise the acid-base and electrolyte effects of shortening the distance required during steeplechase (Phase B) in the face of hot and humid weather conditions during a treadmill-simulated Speed and Endurance test. Eight conditioned Thoroughbred horses underwent 3 randomised permutations of a standardised exercise test on a high speed treadmill. Each test consisted of trotting at 3.7 m/s for 10 min (Phase A); galloping at 11 m/s (Phase B) for 4 (cool laboratory conditions), 3 (hot and humid), or 2 (hot and humid) min; trotting at 3.7 m/s for 30 min (Phase C); an...
Makinde AA.The reverse single radial immunodiffusion technique was used to detect Dermatophilus congolensis antibody in sera collected from animals previously infected to varying levels with D congolensis. Ammonium sulphate and trichloroacetic acid extracts of five different strains of D congolensis obtained from different geographical locations were used as antigens. All the extracts showed variations in their sensitivities in detecting D congolensis antibody in the various serum samples. Multiple antibodies were detected by some extracts while some showed negative antibody reaction to all extracts. Two...
Kaegi B.25 horses which entered the clinic for minor surgery, received ketamine (2.2 mg/kg i.v.) for induction of anesthesia after previous sedation with xylazine (1.1 mg/kg i.v.). As soon as the horses were in the lateral recumbency, the benzodiazepine derivate climazolam was administered at a dose of 0.1 mg/kg i.v. (10 horses) or 0.2 mg/kg i.v. (15 horses). The anesthesia was maintained with repeated injections of ketamine (1.1 mg/kg i.v. every 9-12 minutes). At the end of the surgery, 20 minutes after the last ketamine injection, Ro 15-3505, a benzodiazepine antagonist, was injected at a dose of 0....
He H, Palm-Vlasak LS, Chen C, Banks SA, Biedrzycki AH.This study aims to quantitatively characterize the passive kinematics of the healthy, soft tissue-intact equine stifle to establish an objective foundation for providing insights into the etiology of stifle disorders and developing a possible surgical treatment for stifle degenerative disease. Methods: 5 whole-horse specimens. Methods: Reflective markers with intracortical bone pins and a motion capture system were used to investigate the stifle joint kinematics. Kinematics of 5 whole-horse specimens euthanized within 2 hours were calculated for internal/external rotation, adduction/abduction,...
Zubrod CJ, Farnsworth KD, Tucker RL, Ragle CA.We describe the clinical, imaging, and necropsy findings of two horses with severe injury of the collateral ligaments of the distal interphalangeal (DIP) joint diagnosed using magnetic resonance (MR) imaging. In MR images it was possible to examine the collateral ligaments of the DIP joint from the origin at the middle phalanx to the insertion on the distal phalanx. Both horses in this report had abnormal high signal intensity within the collateral ligaments of the DIP joint, and one horse had abnormal high signal intensity within the bone of the distal phalanx on short tau inversion recovery ...
