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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Viruses, tumours and the MHC.
Equine veterinary journal    September 1, 1993   Volume 25, Issue 5 395 doi: 10.1111/j.2042-3306.1993.tb02980.x
Gerber H, Antczak DF.No abstract available
Giant and binucleate trophoblast cells of mammals.
The Journal of experimental zoology    September 1, 1993   Volume 266, Issue 6 559-577 doi: 10.1002/jez.1402660607
Hoffman LH, Wooding FB.The cellular origin, structure, and function of trophoblastic giant cells (GC) and binucleate cells (BNC) are reviewed. Mammals in which these cells have received the greatest attention include rodents, rabbits, and humans (GCs), and ruminants and equids (BNCs). In almost all cases these cells arise from the cytotrophoblast. All are large cells and contain either two diploid nuclei (BNCs), multiple nuclei (human placental bed GCs), or single nuclei with amplified DNA content (rodent and rabbit GCs). Giant and binucleate cells typically exhibit the capacity for migration or invasion, although t...
Malignant histiocytosis in an Arabian filly.
Equine veterinary journal    September 1, 1993   Volume 25, Issue 5 471-473 doi: 10.1111/j.2042-3306.1993.tb02994.x
Lester GD, Alleman AR, Raskin RE, Mays MB.No abstract available
Retrospective analysis of the results of 151 exploratory laparotomies in horses with gastrointestinal disease.
Equine veterinary journal    September 1, 1993   Volume 25, Issue 5 427-431 doi: 10.1111/j.2042-3306.1993.tb02985.x
Phillips TJ, Walmsley JP.Of 149 horses that underwent 151 exploratory laparotomies for gastrointestinal disorders from September 1987 to May 1991, 107 (72%) were discharged from the hospital: 100 (66%) survived for > 7 months, 94 of which returned to their intended use. Survival rate (64/80) for horses with caecum/large colon obstruction was significantly (P = 0.003) higher than for horses with small intestinal obstruction (33/64). Prolonged surgery was associated with significantly (P < 0.001) lower survival rates than short surgical time. In the large intestine, survival rate (15/29) for strangulated obstructions wa...
Analysis of hemostasis in horses with colic.
Journal of the American Veterinary Medical Association    September 1, 1993   Volume 203, Issue 5 685-693 
Prasse KW, Topper MJ, Moore JN, Welles EG.Eight tests of hemostasis were measured in 233 horses with colic. Blood samples were obtained at admission and for 4 consecutive days of hospitalization. Data were analyzed retrospectively by outcome, by broad-category diagnosis group, by small intestinal disorder, and by smaller categories for comparing specific diseases. Nonsurviving horses and horses with the most severe forms of intestinal ischemia had changes interpreted as hypercoagulative, the intensity of which was increased on the first and second mornings (sample times 2 and 3) after admission, when most significant differences for r...
Computer-assisted three-dimensional gait analysis of amphotericin-induced carpal lameness in horses.
American journal of veterinary research    September 1, 1993   Volume 54, Issue 9 1535-1543 
Peloso JG, Stick JA, Soutas-Little RW, Caron JC, DeCamp CE, Leach DH.Motion of 6 clinically sound horses trotting at a speed of 4 m/s on a treadmill was captured by video cameras before and 9, 16, and 23 days after amphotericin-induced lameness to determine the quantitative variables of three-dimensional computer-assisted image analysis that objectively describe carpal lameness. Amphotericin-B was used to induce lameness, and phenylbutazone (2.2 mg/kg of body weight, PO, once) and butorphanol tartrate (0.1 mg/kg IM, q 6 h, to effect) were used to control discomfort. Four 60-Hz cameras were symmetrically placed around the treadmill to capture 6 seconds of images...
Forelimb lameness associated with radiographic abnormalities of the cervical vertebrae.
Equine veterinary journal    September 1, 1993   Volume 25, Issue 5 422-426 doi: 10.1111/j.2042-3306.1993.tb02984.x
Ricardi G, Dyson SJ.Eight horses had forelimb lameness which was considered unrelated to primary forelimb pain, but was associated with radiographic abnormalities of one or more cervical vertebrae. There was no evidence of ataxia or weakness. The degree and character of the forelimb lameness varied between horses. In 4 horses, selective local analgesic techniques were used to rule out lameness associated with pain in the forelimb. In the other 4 horses, radiographic examination of the cervical region was performed on the basis of forelimb lameness seen in conjunction with neck stiffness and/or neck pain. Three ho...
Purification and characterization of a form of P450 from horse liver microsomes.
Journal of biochemistry    September 1, 1993   Volume 114, Issue 3 445-448 doi: 10.1093/oxfordjournals.jbchem.a124195
Komori M, Higami A, Imai Y, Imaoka S, Funae Y.A form of P450 [termed P450(h-1)] was purified from the liver microsomes of a male horse to electrophoretic homogeneity. The specific content of the final P450(h-1) preparation was 14.8 nmol/mg of protein and the recovery was 0.38% of the microsomal P450. The apparent molecular weight of P450(h-1) was 52,000 Da. The absorption spectra of P450(h-1) indicated that P450(h-1) was a low- and high-spin mixed type P450 in the oxidized form. The reconstituted system containing P450(h-1) could catalyze benzphetamine N-demethylation, 7-ethoxycoumarin O-deethylation, and testosterone 16 alpha-hydroxylati...
Use of orbital implants after enucleation in dogs, horses, and cats: 161 cases (1980-1990).
Journal of the American Veterinary Medical Association    September 1, 1993   Volume 203, Issue 5 701-706 
Hamor RE, Roberts SM, Severin GA.Eye enucleations performed on 109 dogs, 29 horses, and 23 cats involved placement of 136 silicone orbital implants and 7 mesh implants. Mean follow-up times were 2.4 years (range, 3 weeks to 9 years) in dogs, 3.4 years (range, 10 days to 10.5 years) in horses, and 1.5 years (range, 3 weeks to 7.5 years) in cats. Implants failed in 1 of 96 dogs (1.04%), 3 of 29 horses (10.3%), and 3 of 18 cats (16.7%). Implant failure was attributable to various causes in all species; however, cats appeared to be more prone to late extrusion that were dogs and horses. Implantation of an orbital prosthesis was a...
The significance of cardiac auscultatory findings in horses: insight into the age-old dilemma.
Equine veterinary journal    September 1, 1993   Volume 25, Issue 5 393-394 doi: 10.1111/j.2042-3306.1993.tb02979.x
Reef VB.No abstract available
Laboratory diagnosis of strangles and the isolation of atypical Streptococcus equi.
The Veterinary record    August 28, 1993   Volume 133, Issue 9 215-216 doi: 10.1136/vr.133.9.215
Grant ST, Efstratiou A, Chanter N.No abstract available
Determination of the optimal treadmill slope for reproducing the same cardiac response in saddle horses as overground exercise conditions.
The Veterinary record    August 21, 1993   Volume 133, Issue 8 183-185 doi: 10.1136/vr.133.8.183
Barrey E, Galloux P, Valette JP, Auvinet B, Wolter R.The purpose of this study was to define the most suitable treadmill slope for reproducing the same heart rate response as in horses being ridden on a track. Seven French saddle horses were exercised first on a level turf track and then on a treadmill. On the track the exercise test consisted of four periods of three minutes of increasing speeds at the trot and the gallop (96 to 600 m/minute). The treadmill exercise tests consisted of seven steps of increasing slope (0 to 9.6 per cent) at the trot (252 m/minute), followed, after an active recovery period at the walk with a 0 per cent slope, by ...
Osteitis and sequestrum formation of the interdental region of the mandible in 11 polo ponies.
The Veterinary record    August 21, 1993   Volume 133, Issue 8 188-189 doi: 10.1136/vr.133.8.188
Smith JC.No abstract available
Cloning, expression and characterization of horse L-ferritin in Escherichia coli.
Biochimica et biophysica acta    August 19, 1993   Volume 1174, Issue 2 218-220 doi: 10.1016/0167-4781(93)90121-s
Takeda S, Ohta M, Ebina S, Nagayama K.Horse L-ferritin cDNA was cloned from horse liver, and the base sequence was determined. The L-ferritin was expressed using pTZ18U encoding lac promoter, and found to possess an additional 8-amino acid sequence at the N-terminus as compared with commercially obtained horse spleen (natural) ferritin. It was determined that there was Pro at position 94 in both the recombinant and natural L-ferritin, although it was previously reported that Leu was in this position in the natural species. Transmission electron microscopy showed that this recombinant ferritin formed a 24-mer shell.
Stimulated decay of superoxide caused by ferritin-bound copper.
FEBS letters    August 16, 1993   Volume 328, Issue 3 263-267 doi: 10.1016/0014-5793(93)80940-v
Bolann BJ, Ulvik RJ.The redox interaction between O2.- and ferritin cannot solely be regarded as as a Fe(II) release reaction. We demonstrate that native copper bound to horse spleen ferritin and apoferritin, stimulated the decay of O2.- in a catalytic reaction. Copper was determined by atomic absorption spectrophotometry. Decay of O2.- was monitored spectrophotometrically as the decrease in (A250-A360) at pH 9.5. The catalytic effect was linearly related to the copper content of the protein. Ferritin copper was less efficient than equimolar CuCl2, and iron-poor ferritin was more efficient than iron-rich ferritin...
Removal of a fracture fragment from the palmar aspect of the intermediate carpal bone in a horse.
Journal of the American Veterinary Medical Association    August 15, 1993   Volume 203, Issue 4 553-555 
Dabareiner RM, Sullins KE, Bradley W.A 10-year-old Dutch Warmblood gelding sustained a fracture of the palmar tuberosity of the intermediate carpal bone 2 weeks prior to admission. The dorsolateral-palmaromedial oblique and flexed lateromedial radiographic views revealed the fracture line. The palmar fracture fragment from the intermediate carpal bone was removed by arthrotomy of the palmar intercarpal joint, which was approached through the carpal canal. Twenty months after surgery, the horse was show jumping without evidence of lameness.
Seminal vesiculitis as a cause of signs of colic in a stallion.
Journal of the American Veterinary Medical Association    August 15, 1993   Volume 203, Issue 4 556-557 
Freestone JF, Paccamonti DL, Eilts BE, McClure JJ, Swiderski CE, Causey RC.A 5-year-old stallion was referred because of signs of abdominal pain. During the initial examination, signs of pain were elicited when the right seminal vesicle was palpated per rectum. Signs of pain were also elicited during sexual arousal and attempts at semen collection. The right seminal vesicle was subsequently determined to be abnormal by ultrasonographic and endoscopic examination. The stallion was treated with trimethoprim/sulfamethoxazole for 6 weeks. Five months later, there had been no recurrence of the condition.
Disseminated Halicephalobus deletrix infection in a horse.
Journal of the American Veterinary Medical Association    August 15, 1993   Volume 203, Issue 4 550-552 
Ruggles AJ, Beech J, Gillette DM, Midla LT, Reef VB, Freeman DE.A 13-year-old Quarter Horse gelding was referred for evaluation of a draining tract and fracture of the right hemimandible of 4 weeks' duration. Two days prior to admission, the horse had developed pigmenturia. Radiography of the mandible revealed a fracture of the vertical ramus of the right hemimandible, loss of the right lower second premolar, and osteomyelitis involving an extensive portion of the hemimandible. Ultrasonography of the left kidney revealed loss of normal renal architecture. Histologic examination of tissue obtained from the right hemimandible revealed granulomatous osteomyel...
Study aims to keep horses running in the heat of Atlanta.
The Veterinary record    August 7, 1993   Volume 133, Issue 6 126 doi: 10.1136/vr.133.6.126
No abstract available
Nucleation of the iron core occurs at the three-fold channels of horse spleen apoferritin: an EXAFS study on the native and chemically-modified protein.
Biochimica et biophysica acta    August 7, 1993   Volume 1164, Issue 3 331-334 doi: 10.1016/0167-4838(93)90267-u
Strange R, Morante S, Stefanini S, Chiancone E, Desideri A.Extended X-ray absorbance fine structure measurements have been carried out on the initial Fe(III)-apoferritin complex at a Fe/subunit ratio of 2 in native and modified horse spleen apoferritin. Analysis of the data indicates that in the native protein the iron forms a protein-bound polynuclear cluster (Fe-Fe distance 3.4 A) with a first coordination sphere constituted by 5-6 low-Z atoms, e.g., nitrogen atoms, carboxylate-like ligands or oxo bridges between the iron atoms. Modification of Cys-126, a residue localized on the outer surface of the hydrophilic three-fold channels, with p-chloromer...
Evaluation of agar gel immunodiffusion and indirect fluorescent antibody assays as supplemental tests for dourine in equids.
American journal of veterinary research    August 1, 1993   Volume 54, Issue 8 1201-1208 
Hagebock JM, Chieves L, Frerichs WM, Miller CD.The agar gel immunodiffusion (AGID) and indirect fluorescent antibody (IFA) assays were evaluated as supplemental tests to the complement-fixation (CF) test, the official US importation certification test for dourine in equids. The American stabilate (n = 10 animals) or the Canadian stabilate (n = 6 animals) of Trypanosoma equiperdum cultured in rat blood was administered by catheterization and infusion in the urogenital tract of 16 equids. To assess parasitemia and serologic responses by use of the CF, AGID, and IFA tests, a total of 787 serum and blood samples were obtained from equids befor...
Evaluation of the effect of alfentanil on the minimum alveolar concentration of halothane in horses.
American journal of veterinary research    August 1, 1993   Volume 54, Issue 8 1327-1332 
Pascoe PJ, Steffey EP, Black WD, Claxton JM, Jacobs JR, Woliner MJ.The effect of 3 plasma concentrations of alfentanil on the minimum alveolar concentration (MAC) of halothane in horses was evaluated. Five healthy geldings were anesthetized on 3 occasions, using halothane in oxygen administered through a mask. After induction of anesthesia, horses were instrumented for measurement of blood pressure, airway pressure, and end-tidal halothane concentrations. Blood samples, for measurement of pH and blood gas tensions, were taken from the facial artery. Positive pressure ventilation was begun, maintaining PaCO2 at 49.1 +/- 3.3 mm of Hg and airway pressure at 20 +...
Diversity within natural populations of eastern equine encephalomyelitis virus.
Virology    August 1, 1993   Volume 195, Issue 2 700-709 doi: 10.1006/viro.1993.1421
Weaver SC, Bellew LA, Gousset L, Repik PM, Scott TW, Holland JJ.We evaluated genetic and phenotypic diversity within natural populations of the alphavirus, Eastern equine encephalomyelitis (EEE) virus. RNA fingerprinting revealed that most populations within infected hosts (unpassaged isolates) contained a consensus genotype along with minority genotypes differing in one to three T1-resistant oligonucleotides. Mutation frequencies appeared to be similar to those reported for other RNA viruses, suggesting that the slow rate of EEE virus evolution is not limited by fidelity of genome replication. Within a given year, genetic diversity was generally greater a...
Intraarticular hyaluronan injections in the treatment of osteoarthritis: state-of-the-art review.
The Journal of rheumatology. Supplement    August 1, 1993   Volume 39 10-15 
Peyron JG.Viscosupplementation (restoring the rheological properties of a tissue matrix) by injection of hyaluronan into the joints has been in use for 2 decades, mostly for osteoarthritis (OA) of the knee, using doses of 20-25 mg of hyaluronan of 500,000 to 2,500,000 M(r), in sequences of 2 to 10 weekly injections. Pain relief appears in a few days, progresses over a few weeks, and often lasts several months. Some data suggest the benefit can last 6 months to one year. Tolerance is universally reported as very good. Those responding to hyaluronan are 65-80%, compared to 30-35% responding to control. Co...
Vesicular stomatitis in the horse.
The Veterinary clinics of North America. Equine practice    August 1, 1993   Volume 9, Issue 2 349-353 doi: 10.1016/s0749-0739(17)30401-7
Green SL.Vesicular stomatitis (VS) is a viral disease of livestock that results in vesicles and ulcerations on the teats, oral mucosa, tongue, and coronary bands. All three main serotypes of the VS virus can infect the horse. Although VS does not have a major impact on the equine industry, it is clinically identical to the other more economically devastating vesicular diseases of cattle and swine and can produce influenza-like symptoms in humans. VS in horses is reportable, as are all vesicular diseases of livestock.
Left dorsal displacement of the colon with splenic adhesions in three horses.
Journal of the American Veterinary Medical Association    August 1, 1993   Volume 203, Issue 3 425-427 
Moll HD, Schumacher J, Dabareiner RM, Slone DE.Three horses underwent exploratory celiotomy because of signs of acute abdominal pain. At surgery, all horses were diagnosed as having left dorsal displacement of the large colon. Each surgery was complicated by fibrous adhesions of the spleen to the body wall. All horses had previously undergone abdominal surgery for colic. In these cases, it appeared that the left large colon displaced cranially and then entered the renosplenic space from a cranial to caudal direction. Adhesions of the spleen to the body wall would prevent correction of left dorsal displacement of the large colon by the roll...
[Ganglioside GM3 from horse erythrocytes: structure and effect on cell proliferation].
Bioorganicheskaia khimiia    August 1, 1993   Volume 19, Issue 8 817-824 
Menzeleev RF, Smirnova GP, Chekareva NV, Zvonkova EN, Krasnopol'skiĭ IuM, Shvets VI.An increase of the mouse fibroblast proliferation by ganglioside GM3 from equine erythrocytes is described. The structure of GM3 has been established on the basis of chemical methods, enzymatic degradation, GC-MS, as well as plasma desorption mass spectrometry and HPLC of 9-anthrylmethyl esters of gangliosides to characterize the long-chain base composition. The oligosaccharide moiety includes an N-glycolylneuraminic acid residue, whereas the main components of the lipid moiety are 20:1 sphingosine and 24:0 fatty acids.
Viscosupplementation: a new concept in the treatment of osteoarthritis.
The Journal of rheumatology. Supplement    August 1, 1993   Volume 39 3-9 
Balazs EA, Denlinger JL.Viscosupplementation is a new medical concept that has as its therapeutic goal the restoration of rheological homeostasis in pathological structures such as osteoarthritic joints. When the normal viscoelasticity of a solid tissue compartment or the elastoviscosity of a liquid tissue compartment is decreased under pathological conditions, normal function and regenerative processes are impaired. By introducing viscosupplementary devices, the normal rheological state of such compartments is restored or augmented. These devices stay in the tissue compartment for various periods of time, depending ...
Flow reversal through a Mark III halothane vaporizer.
British journal of anaesthesia    August 1, 1993   Volume 71, Issue 2 303-304 doi: 10.1093/bja/71.2.303
Gregg AS, Jones RS, Snowdon SL.A fault in the assembly of a Matrix Large Animal Circle anaesthetic machine resulted in reversal of fresh gas flow through the vaporizer. The fault was discovered only after the sudden development of excessive depth of anaesthesia in two equine patients. Laboratory investigations were conducted to determine the effect of flow reversal on vaporizer output. Results indicated that output concentration was approximately doubled under these conditions.
Rotaviral diarrhea.
The Veterinary clinics of North America. Equine practice    August 1, 1993   Volume 9, Issue 2 311-319 doi: 10.1016/s0749-0739(17)30398-x
Dwyer RM.Rotavirus poses a challenge each foaling season to farm managers and veterinarians in intensive horse breeding areas throughout the world. By understanding the epidemiology of the disease as well as characteristics of the virus, veterinarians can make sound recommendations on prevention and control of outbreaks. Even when effective prophylactic products are developed, farm management practices, including quarantine, disinfection, and hygiene, will always need to be in force to prevent any contagious disease outbreak.