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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Serological titers of equine monocytic ehrlichiosis associated with gastro-intestinal disorders and serological follow-up on two endemic farms.
Veterinary microbiology    April 1, 1993   Volume 34, Issue 4 345-353 doi: 10.1016/0378-1135(93)90059-g
Farrar WP, Bech-Nielsen S, Gordon JC, Reed SM, Pretzman CI, Kohn CW.The purpose of this work was to study the association of positive serological titers to Ehrlichia risticii, the causative agent of equine monocytic ehrlichiosis (EME) with gastro-intestinal disorders in hospitalized horses referred to The Ohio State University College of Veterinary Medicine Teaching Hospital (OSU VMTH). In addition, serological titers for E. risticii were monitored in two horse populations with endemic EME for one season to monitor temporal changes in titers. A statistically significant difference was found between the proportion of the total hospitalized horse population pres...
A novel response of anion transporter in equine erythrocytes to a fluorescent substrate, N-(2-aminoethyl sulfonate)-7-nitrobenz-2-oxa-3-diazole (NBD-taurine).
The Journal of veterinary medical science    April 1, 1993   Volume 55, Issue 2 281-285 doi: 10.1292/jvms.55.281
Inaba M, Goto I, Sato K, Maede Y.This report describes a unique response of the anion transporter in equine erythrocytes to the fluorescent substrate N-(2-aminoethyl sulfonate)-7-nitrobenz-2-oxa-3-diazole (NBD-taurine). Equine erythrocytes showed fluxes of NBD-taurine both inward and outward at rates considerably slower than those in human cells. These fluxes were completely abolished by a typical anion transport inhibitor, 4,4'-diisothiocyanostilbene-2,2'-disulfonate. Furthermore, NBD-taurine competitively inhibited the uptake of phosphate in equine red cells with an inhibition constant of phosphate that was slightly higher ...
Successful resection of a recurrent leiomyosarcoma of the pulmonary trunk.
The Annals of thoracic surgery    April 1, 1993   Volume 55, Issue 4 1009-1012 doi: 10.1016/0003-4975(93)90139-9
Okada K, Okada M, Yamamoto S, Mukai T, Tsukube T, Matsuda H, Okada M.We successfully performed a total resection of the pulmonary artery trunk and replaced it with an equine pericardial xenograft roll in a patient with a recurrent leiomyosarcoma. We believe, based on anatomic and embryologic principles, total rather than partial resection of the pulmonary artery trunk should be the treatment of choice for primary leiomyosarcomas of the pulmonary artery.
Neoplasia.
The Veterinary clinics of North America. Equine practice    April 1, 1993   Volume 9, Issue 1 213-234 doi: 10.1016/s0749-0739(17)30425-x
Hance SR, Bertone AL.Equine tumors are rather uncommon; however, of the body regions, the head is a relatively common location for neoplasia, including sarcoids and squamous cell carcinomas of the skin, tumors of the sinus/nasal cavity, and bony tumors of the head. Tumors discussed in the article include odontogenic and bony tumors; sarcoids; tumors of the guttural pouch and pharyngeal and oral mucosa; tumors of the larynx; and tumors of the paranasal sinuses and nasal passages. In general, tumors involving deeper structures of the head carry a poor prognosis; however, some tumors such as sarcoids, ossifying fibro...
Foetal endocrine maturation.
Equine veterinary journal. Supplement    April 1, 1993   Issue 14 35-40 doi: 10.1111/j.2042-3306.1993.tb04807.x
Challis JR, Bassett N, Berdusco ET, Han VK, Lu F, Riley SC, Yang K.In domestic ruminants such as the sheep, birth is effected through sequential maturation of the foetal hypothalamic-pituitary-adrenal (HPA) axis, leading to the increased output of cortisol. Factors regulating foetal pituitary adrenocorticotrophin (ACTH) secretion have been delineated, and these include corticotrophin releasing hormone (CRH), arginine vasopressin, prostaglandin (PG) E2 and endogenous opioids. The pre-partum increase in foetal plasma ACTH is associated with a rise in pro-opiomelanocortin (POMC) mRNA in the foetal pars distalis, and with an altered pattern of POMC post-translati...
[Equine granulocytic ehrlichiosis (EGE), a review].
Tijdschrift voor diergeneeskunde    April 1, 1993   Volume 118, Issue 7 227-229 
van der Kolk JH, van der Wijden MW, Jongejan F.Equine granulocytic ehrlichiosis (EGE) has been observed in the U.S.A., Brazil, Germany, Sweden, Switzerland and possibly in Great Britain. The causative agent is rickettsia Ehrlichia equi, identified for the first time in 1969. The clinical features of the disease are anorexia, fever, depression, (limb) oedema, icterus, ataxia, petechiae and orchitis. Hematologic changes are leukopenia, thrombocytopenia, anemia and cytoplasmic inclusion bodies in the neutrophils and eosinophils. Vasculitis may be observed at autopsy. Following a positive hematological diagnosis (Giemsa stained blood smear) of...
Clostridium septicum septicemia in a neonatal foal with hemorrhagic enteritis.
The Cornell veterinarian    April 1, 1993   Volume 83, Issue 2 143-151 
Jones SL, Wilson WD.Clostridium septicum was isolated by anaerobic culture of blood collected from a 3-day-old foal with hemorrhagic enteritis and signs suggestive of septicemia. The foal responded well to treatment with intravenous fluids, antibiotics, plasma, and oral gastrointestinal protectants. One month after apparent complete recovery from the septicemia and hemorrhagic enteritis, the foal was euthanized during an acute episode of colic that was caused by severe, strangulating intestinal adhesions, thought to have formed as a result of peritonitis secondary to the hemorrhagic enteritis. The value of anaero...
Pulmonary edema associated with transient airway obstruction in three horses.
Journal of the American Veterinary Medical Association    April 1, 1993   Volume 202, Issue 7 1116-1118 
Kollias-Baker CA, Pipers FS, Heard D, Seeherman H.Pulmonary edema associated with transient airway obstruction was detected in 3 horses. The cause of obstruction was different in each horse, but after relief of the obstruction, clinical signs and radiographic abnormalities were indicative of pulmonary edema. In 2 of the 3 horses, pink frothy fluid was evident in the airways. The horses were treated with furosemide, nasal insufflation of O2, anti-inflammatory agents, and anti-biotics. Of the 3 horses examined, 1 horse died acutely, 1 horse recovered fully, and 1 developed pleuritis and was subsequently euthanatized.
Examination of the oral cavity and routine dental care.
The Veterinary clinics of North America. Equine practice    April 1, 1993   Volume 9, Issue 1 123-131 doi: 10.1016/s0749-0739(17)30419-4
Scrutchfield WL, Schumacher J.Techniques and equipment used to examine the oral cavity thoroughly are explained. Common routine dental procedures described include removal of enamel points, wolf teeth, and retained caps. Abnormalities of the incisors are discussed.
A one-way (non-rebreathing) valve suitable for use in gas analysis of exercising horses.
Australian veterinary journal    April 1, 1993   Volume 70, Issue 4 151-152 doi: 10.1111/j.1751-0813.1993.tb06111.x
Slocombe RF, Bayly WM.No abstract available
Serum levels of testosterone and oestrogens in normal and infertile stallions.
International journal of andrology    April 1, 1993   Volume 16, Issue 2 155-158 doi: 10.1111/j.1365-2605.1993.tb01169.x
Inoue J, Cerbito WA, Oguri N, Matsuzawa T, Sato K.The serum concentrations of testosterone and oestrogens were determined in stallions classified as geldings, normal (according to age) or infertile (azoospermic). There were significant differences in testosterone and oestrogen levels between the groups. Normal concentrations of testosterone and total oestrogens were attained after 16 months of age. Castrated and immature horses ( 4 years). The results suggest that serum levels of testosterone and total oestrogens may provide a sensitive index of the endocrine function of the testis in male horses.
[Pain prevention and pain treatment in small and large domestic animals].
Tierarztliche Praxis    April 1, 1993   Volume 21, Issue 2 87-94 
Sager M.The aim of this article is to emphasize the need for analgesic medication in animals in possibly painful situations, especially in the postoperative period. The two large groups of compounds used as analgesics--the opiates and the nonsteroidal antiinflammatory drugs (NSAIDs)--are described with special reference to their pharmacokinetics, side-effects and toxicity, their mechanism of action, their indications and contraindications. Recommended doses of the different drugs available are given for the dog, the cat, the horse, the swine and the small and large ruminants.
Effect of influenza A/equine/H3N8 virus isolate variation on the measurement of equine antibody responses. Bogdan JR, Morley PS, Townsend HG, Haines DM.This study has tested the effect of using homologous or heterologous equine influenza A virus isolates to evaluate serum antibody levels to influenza A virus in vaccinated and naturally-infected horses. In addition, the potential effect of antigenic selection of virus variants in egg versus tissue culture propagation systems was studied. Serum antibody levels in samples from horses recently infected with a local influenza A virus isolate (A/equine 2/Saskatoon/1/90) or recently vaccinated with a prototype isolate (A/equine 2/Miami/1/63) were assessed by hemagglutination inhibition and by single...
Clinical examination of the equine head.
The Veterinary clinics of North America. Equine practice    April 1, 1993   Volume 9, Issue 1 25-48 doi: 10.1016/s0749-0739(17)30414-5
MacDonald MH.Examination of the equine head should be a routine part of any complete physical examination. It can be performed rapidly and efficiently while providing important information about the health and function of several major body systems.
[Post-epizootic activity of Western equine encephalitis virus in Argentina].
Revista Argentina de microbiologia    April 1, 1993   Volume 25, Issue 2 88-99 
Aviles G, Bianchi TI, Daffner JF, Sabattini MS.It is shown here the WEE virus activity in ARgentina in 1983-1986 post-epizootic period. A surveillance system was established by the equine case notification and the sentinel animal method. Among the thirteen equine focus notified between September 1983-September 1985 in Córdoba and Santa Fe Provinces, 5 presumptive cases out of 16 sick horses were confirmed by the hemagglutination inhibition test for WEE epizootic virus. Twenty eight notified human cases were studied with negative results. The neutralizing antibody (Ac NT) prevalence among sentinel horses in Córdoba Province (4%) was lower...
Congenital diseases of the equine head.
The Veterinary clinics of North America. Equine practice    April 1, 1993   Volume 9, Issue 1 93-110 doi: 10.1016/s0749-0739(17)30417-0
Gaughan EM, DeBowes RM.Many questions concerning heritability arise when a veterinarian is asked to supervise and treat disease of congenital origin. Genetic counseling, ethics, and legality are often confronted in discussions between animal health professionals and laymen in animal industry. Guidelines have been offered as in the 1984 statement of the Judicial Council of the American Veterinary Medical Association: "Performance of surgical procedures in all species for the purpose of concealing genetic defects in animals to be shown, raced, bred, or sold as breeding animals is unethical. However, should the health ...
Seroepidemiological survey of chlamydial infections in light horses in Japan.
The Journal of veterinary medical science    April 1, 1993   Volume 55, Issue 2 333-335 doi: 10.1292/jvms.55.333
Miyamoto C, Takashima I, Karaiwa H, Sugiura T, Kamada M, Hashimoto N.To investigate the overall prevalence of chlamydial infections in light (i.e. non-draught) horses in Japan, 599 sera obtained from 12 localities in 1991 were tested for complement fixation antibodies. The mean antibody positive rates of the all sera were 15.2% (91/599) and the regional positive rates were higher in Honshu (19.1%, 48/251) and Kyushu (20.0%, 20/100) than in Hokkaido (9.3%, 23/248). In Honshu, the highest rate (56.0%, 28/50) was observed in Utsunomiya. Analysis of the positive rate in different age groups showed that the 2-5 years age-group had the highest prevalence of chlamydia...
Some aspects of perinatal maturation and adaptation.
Equine veterinary journal. Supplement    April 1, 1993   Issue 14 17-22 doi: 10.1111/j.2042-3306.1993.tb04803.x
Mellor DJ.Physiological challenges facing the perinatal individual are huge. This is partly because of the marked and abrupt change from the intrauterine to the extrauterine environment, but also because the physiological responses to that change depend upon systems whose maturation is affected markedly by birth. Perinatal maturation appears, therefore, both to precede and accompany the physiological adaptations required for neonatal survival. This review does not provide a comprehensive coverage of perinatal physiology but directs attention towards evaluating constraints on foetal and neonatal thermoge...
Growth hormone (GH) secretory pattern and GH response to GH-releasing factor (GRF) or thyrotropin-releasing hormone (TRH) in newborn foals.
Journal of developmental physiology    April 1, 1993   Volume 19, Issue 4 143-147 
Davicco MJ, Coxam V, Faulconnier Y, Dubroeucq H, Martin-Rosset W, Barlet JP.The present study was undertaken to assess GH secretory profiles in 12 light-breed foals and their dams during forty days after delivery, and the possible influence of GRF and TRH on plasma GH concentrations in these newborn foals. GH secretory pattern was pulsatile in one day- as well as in forty days-old foals. The number of secretory spikes (10 per 24 h) did not vary between days 1 and 40. In the same times, GH secretion did not show any circadian rhythm either in foals or in their dams. Mean daily plasma concentrations (measured through blood samples collected every 20 min for 24 h) were l...
Proto-oncogene of genomic DNA, related to the human epidermal growth factor receptor (EGFR) gene, from clinically normal domestic animals.
The Journal of veterinary medical science    April 1, 1993   Volume 55, Issue 2 319-321 doi: 10.1292/jvms.55.319
Kai K, Tateyama S, Miyoshi N, Yamaguchi R, Uchida K, Rostami M.Genomic DNAs of cattle, horses, pigs, dogs, cats and chickens were surveyed using Southern blot hybridization analysis, with a human EGFR cDNA fragment. Several bands with different numbers and molecular weights were observed under the condition of low stringency in the individual animal species. The bands showing DNA polymorphism were observed among bovine genomic PstI-digested DNAs from 4 individuals and EcoRI-digested genomic DNAs from 4 chickens. These results may provide basic data which are useful for analysis of tumorigenetic mechanisms in domestic animals.
Development of gastrointestinal functions in the foal: what can we learn from studies on man and experimental animals?
Equine veterinary journal. Supplement    April 1, 1993   Issue 14 23-25 doi: 10.1111/j.2042-3306.1993.tb04804.x
Koldovsky O.No abstract available
A speculative review of parturition in the mare.
Equine veterinary journal. Supplement    April 1, 1993   Issue 14 41-49 doi: 10.1111/j.2042-3306.1993.tb04808.x
Thorburn GD.No abstract available
Pharmacokinetics and concentrations of ceftiofur sodium in body fluids and endometrium after repeated intramuscular injections in mares.
American journal of veterinary research    April 1, 1993   Volume 54, Issue 4 573-575 
Cervantes CC, Brown MP, Gronwall R, Merritt K.Each of 5 healthy mares was given 5 consecutive IM injections of ceftiofur sodium (2 mg/kg of body weight; 50 mg/ml) at 12-hour intervals. Ceftiofur concentrations were measured serially in serum, synovial fluid, peritoneal fluid, and urine, and were measured in CSF and endometrial tissue after the fifth dose. Mean elimination rate constant was 0.354 +/- 0.101 h-1 and elimination half-life was 2.49 +/- 0.49 hour. Mean serum ceftiofur concentrations peaked approximately 1 hour after each injection. The highest mean ceftiofur concentration was 5.09 micrograms/ml at 1 hour after the fifth dose fo...
Correlations between histologic endometrial lesions in mares and clinical response to intrauterine exposure with Streptococcus zooepidemicus.
American journal of veterinary research    April 1, 1993   Volume 54, Issue 4 570-572 
Troedsson MH, deMoraes MJ, Liu IK.The relationship between histologic lesions in endometrial biopsy specimens and susceptibility to chronic uterine infection (CUI) in mares was investigated. Mares were allotted to 4 groups on the basis of degree of endometrial lesions. Mares in group 1 (n = 6) had no pathologic changes, mares in group 2 (n = 5) had only mild pathologic changes, group-3 mares (n = 7) had moderate changes, and group-4 mares (n = 7) had severe inflammatory and fibrotic endometrial changes. Susceptibility to CUI was determined by the inflammatory response to intrauterine inoculation of 5 x 10(6) Streptococcus zooe...
Phenotypic analysis of peripheral blood and bronchoalveolar lavage fluid lymphocytes in control and chronic obstructive pulmonary disease affected horses, before and after ‘natural (hay and straw) challenges’.
Veterinary immunology and immunopathology    April 1, 1993   Volume 36, Issue 3 207-222 doi: 10.1016/0165-2427(93)90020-5
McGorum BC, Dixon PM, Halliwell RE.Phenotypic analysis of lymphocytes in peripheral blood (PB) and bronchoalveolar lavage fluid (BALF) of control and chronic obstructive pulmonary disease (COPD) affected horses, both before and after 'natural (hay and straw) challenge', were performed using immunofluorescent labelling with monoclonal antibodies and flow cytometry. BALF lymphocytes were shown to be predominantly EqCD5+ cells, approximately half of which were also EqCD8+, with a smaller proportion of B cells. In comparison with PB, BALF contained higher proportions of EqCD5+ cells and EqCD8+ cells and a lower proportion of B cell...
Hemorrhage into the guttural pouch (auditory tube diverticulum) associated with rupture of the longus capitis muscle in three horses.
Journal of the American Veterinary Medical Association    April 1, 1993   Volume 202, Issue 7 1129-1131 
Sweeney CR, Freeman DE, Sweeney RW, Rubin JL, Maxson AD.Three horses were determined to have hemorrhage into a guttural pouch unassociated with mycosis, empyema, neoplasia, or foreign body. The source of the hemorrhage appeared to be the rupture of the longus capitis muscle and its associated vascular supply.
Pyrrolizidine alkaloidosis in a two month old foal.
Zentralblatt fur Veterinarmedizin. Reihe A    April 1, 1993   Volume 40, Issue 3 213-218 doi: 10.1111/j.1439-0442.1993.tb00619.x
Small AC, Kelly WR, Seawright AA, Mattocks AR, Jukes R.A foal, small and jaundiced from birth, succumbed after two months to chronic hepatic damage which was characterised by fibrosis, biliary ductular hyperplasia and the presence of pleomorphic hepatocytes containing either a single large nucleus or multiple nuclei. The fixed liver contained sulfur-bound pyrroles, which are derived from pyrrolizidine alkaloids. During pregnancy the pasture was heavily infested with the pyrrolizidine alkaloid-containing plant, Senecio madagascariensis. The hepatic disease affecting the foal appears to have been initiated by consumption of the alkaloids by the mare...
[Spavin in horses–clinical, radiological and scintigraphic findings].
Tierarztliche Praxis    April 1, 1993   Volume 21, Issue 2 141-148 
Driesang I, Böhm D.Both hock joints were examined clinically, radiologically and scintigraphically in 80 horses with special regard to bone spavin. The positive x-ray and bone scan results corresponded in most cases. It was evident that there was no correlation between degree of lameness and/or extent of radiological findings and increased radioactive uptake in the joint. Scintigraphic evaluation may demonstrate early changes at the onset of bone spavin as well as the frequent bilateral nature of the condition.
Quantification of histamine in plasma and pulmonary fluids from horses with chronic obstructive pulmonary disease, before and after ‘natural (hay and straw) challenges’.
Veterinary immunology and immunopathology    April 1, 1993   Volume 36, Issue 3 223-237 doi: 10.1016/0165-2427(93)90021-u
McGorum BC, Dixon PM, Halliwell RE.A commercial radioimmunoassay kit was used to quantify histamine concentrations of plasma, bronchoalveolar lavage fluid (BALF) and pulmonary epithelial lining fluid (PELF) of normal horses and horses with chronic obstructive pulmonary disease (COPD), before and after 'natural (hay and straw) challenge' (NC). There were no significant changes in the concentrations of histamine in plasma or BALF at 0.5 or 5 h after NC, but the PELF histamine concentration of COPD affected horses was significantly increased at 5 h, but not at 0.5 h, following NC. As the histamine concentrations of whole BALF lysa...
[The clinical case. Warmblood foal, male, 3 days old].
Tierarztliche Praxis    April 1, 1993   Volume 21, Issue 2 102-173 
Bostedt H.No abstract available