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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Effects of bites by the European adder (Vipera berus) in seven Swedish horses.
The Veterinary record    May 20, 2008   Volume 162, Issue 20 652-656 doi: 10.1136/vr.162.20.652
Anlén KG.The effects on seven horses of bites by the European adder (Vipera berus) are described and compared with previously available information. The clinical signs varied from local swelling and mild systemic signs to severe systemic signs, including systemic inflammatory response, severe tissue necrosis, ventricular tachycardia and dysphagia. Two of the horses were treated with 'Zagreb' antiserum, and three that were not treated with antiserum were euthanased owing to complications related to the bites.
Regional pulmonary veno-occlusion: a newly identified lesion of equine exercise-induced pulmonary hemorrhage.
Veterinary pathology    May 20, 2008   Volume 45, Issue 3 316-326 doi: 10.1354/vp.45-3-316
Williams KJ, Derksen FJ, de Feijter-Rupp H, Pannirselvam RR, Steel CM, Robinson NE.Exercise-induced pulmonary hemorrhage (EIPH) is common in horses following intense exertion, occurring in up to 75% of racing Thoroughbreds and Standardbreds. In spite of this, the pathogenesis of EIPH is poorly understood. In 7 racing Thoroughbred horses with EIPH, 6 sections were collected from the left and right lung, representing the cranial, middle, and caudal region of the dorsal and ventral lung (84 sites total). Grossly, both right and left lungs had numerous dark brown to blue-black foci along the caudodorsal visceral pleura. Tissue sections were stained with hematoxylin-eosin, Masson...
Characterisation of the inflammatory reaction in equine idiopathic focal eosinophilic enteritis and diffuse eosinophilic enteritis.
Equine veterinary journal    May 20, 2008   Volume 40, Issue 4 386-392 doi: 10.2746/042516408X312112
Mäkinen PE, Archer DC, Baptiste KE, Malbon A, Proudman CJ, Kipar A.Idiopathic focal eosinophilic enteritis (IFEE) and diffuse eosinophilic enteritis (DEE) are primary eosinophilic intestinal conditions without a known cause that are associated with an increasing number of surgical colic cases. Histology may be helpful in defining disease aetiology and pathogenesis. Objective: To characterise further the inflammatory infiltrate in equine IFEE and to compare the condition with DEE. Methods: Twenty-three IFEE cases and 5 DEE cases were examined by light microscopy including immunohistology to identify infiltrating leucocytes. Inflammatory infiltrates in mucosa a...
Equine gastrointestinal motility research: where we are and where we need to go.
Equine veterinary journal    May 20, 2008   Volume 40, Issue 4 422-428 doi: 10.2746/042516408X312932
Hudson NP, Merritt AM.Equine gastrointestinal motility is a central issue in cases of equine colic, post operative convalescence and alimentary conditions encountered in practice. There are significant syndromes of intestinal dysmotility in the horse such as obstructive disorders and post operative ileus that are still poorly understood. This review describes the various areas of research that aim to elucidate the pathogenesis of intestinal hypo- or hypermotility by research methods, which include studies at the cellular level, and those that employ in vitro or in vivo techniques of evaluating the physiology and me...
Effects of topical administration of 1% brinzolamide on intraocular pressure in clinically normal horses.
Equine veterinary journal    May 20, 2008   Volume 40, Issue 7 662-665 doi: 10.2746/042516408X297426
Germann SE, Matheis FL, Rampazzo A, Burger D, Roos M, Spiess BM.Only few drugs with limited efficacy are available for topical treatment of equine glaucoma. Objective: To evaluate the effect of topical administration of 1% brinzolamide on intraocular pressure (IOP) in clinically normal horses. Methods: Healthy mature horses (n = 20) with normal ocular findings, were studied. The IOP was measured 5 times daily (07.00, 11.00, 15.00, 19.00 and 23.00 h) over 10 days. On Days 1 and 2, baseline values were established. On Days 3-5 one eye of each horse was treated with one drop of 1% brinzolamide every 24 h immediately following the 07.00 h measurement. On Days ...
Intra-articular stabilisation of the equine cricoarytenoid joint.
Equine veterinary journal    May 20, 2008   Volume 40, Issue 6 584-588 doi: 10.2746/042516408X313643
Cheetham J, Witte TH, Rawlinson JJ, Soderholm LV, Mohammed HO, Ducharme NG.The success of laryngoplasty is limited by abduction loss in the early post operative period. Objective: To determine the efficacy of polymethylmethacrylate (PMMA) in stabilising the cricoarytenoid joint (CAJ) and reducing the force on the laryngoplasty suture. Objective: Injection into the cricoarytenoid joint resists the forces produced by physiological laryngeal air flows and pressures thereby reducing the force experienced by the laryngoplasty suture. Methods: Ten cadaver larynges were collected at necropsy and PMMA was injected into one CAJ at selected random. Each larynx was subjected to...
Exercise induced stress in horses: selection of the most stable reference genes for quantitative RT-PCR normalization.
BMC molecular biology    May 19, 2008   Volume 9 49 doi: 10.1186/1471-2199-9-49
Cappelli K, Felicetti M, Capomaccio S, Spinsanti G, Silvestrelli M, Supplizi AV.Adequate stress response is a critical factor during athlete horses' training and is central to our capacity to obtain better performances while safeguarding animal welfare. In order to investigate the molecular mechanisms underlying this process, several studies have been conducted that take advantage of microarray and quantitative real-time PCR (qRT-PCR) technologies to analyse the expression of candidate genes involved in the cellular stress response. Appropriate application of qRT-PCR, however, requires the use of reference genes whose level of expression is not affected by the test, by ge...
Persistently infected horses are reservoirs for intrastadial tick-borne transmission of the apicomplexan parasite Babesia equi.
Infection and immunity    May 19, 2008   Volume 76, Issue 8 3525-3529 doi: 10.1128/IAI.00251-08
Ueti MW, Palmer GH, Scoles GA, Kappmeyer LS, Knowles DP.Tick-borne pathogens may be transmitted intrastadially and transstadially within a single vector generation as well as vertically between generations. Understanding the mode and relative efficiency of this transmission is required for infection control. In this study, we established that adult male Rhipicephalus microplus ticks efficiently acquire the protozoal pathogen Babesia equi during acute and persistent infections and transmit it intrastadially to naïve horses. Although the level of parasitemia during acquisition feeding affected the efficiency of the initial tick infection, infected t...
Gastric and small intestinal ileus as a cause of acute colic in the post parturient mare.
Equine veterinary journal    May 17, 2008   Volume 40, Issue 4 368-372 doi: 10.2746/042516408X302483
Hillyer MH, Smith MR, Milligan PJ.Ileus (functional obstruction of aboral gastrointestinal transit) is an uncommon cause of gastrointestinal dysfunction and colic in the horse. A number of specific conditions have been previously reported in association with ileus. This report describes the recognition of primary gastric and small intestinal ileus of undetermined cause in a series of post parturient mares. Objective: To describe the clinical features, treatment and outcome of a series of episodes of primary gastric and small intestinal ileus. Methods: A retrospective study was performed of colic episodes seen in an equine prac...
Granulomatous pneumonia, lymphadenopathy, and hepatopathy in an adult horse with repeated injection of BCG.
Journal of veterinary internal medicine    May 17, 2008   Volume 22, Issue 4 1056-1060 doi: 10.1111/j.1939-1676.2008.0104.x
van den Boom R, Veldhuis Kroeze EJ, Klein WR, Houwers DJ, van der Zanden AG, Sloet van Oldruitenborgh-Oosterbaan MM.No abstract available
The effect of metformin on measurements of insulin sensitivity and beta cell response in 18 horses and ponies with insulin resistance.
Equine veterinary journal    May 17, 2008   Volume 40, Issue 5 493-500 doi: 10.2746/042516408X273648
Durham AE, Rendle DI, Newton JE.Laminitis in equids is a very common debilitating disease, and insulin resistance (IR) and hyperinsulinaemia are increasingly recognised as important predisposing factors. Pharmacological modification of IR and hyperinsulinaemia might reduce the risk of laminitis. Objective: Metformin, a drug commonly prescribed for treatment of human IR, may also decrease IR in equids. Methods: Eighteen horses and ponies with IR and recurrent laminitis were treated with 15 mg/kg bwt metformin per os q. 12 h. Each animal served as its own control by comparing pre- and post treatment proxies for IR, insulin sen...
Medical and surgical management of uroperitoneum in a foal.
The Canadian veterinary journal = La revue veterinaire canadienne    May 17, 2008   Volume 49, Issue 4 401-403 
Butters A.A 4-day-old, male, American paint foal was presented for abdominal distention, respiratory distress, and diarrhea. Bladder rupture and uroperitoneum were diagnosed following abdominal ultrasonography and abdominocentesis. The defect in the dorsocranial part of the bladder wall was surgically repaired. Un poulain American Paint mâle âgé de quatre jours est présenté pour ballonnement abdominal, détresse respiratoire et diarrhée. Une rupture de la vessie et un uropéritoine sont diagnostiqués après une échographie et une paracentèse abdominale. Le défaut dans la partie dorso-crânial...
The effects of Strongylus vulgaris parasitism on eosinophil distribution and accumulation in equine large intestinal mucosa.
Equine veterinary journal    May 17, 2008   Volume 40, Issue 4 379-384 doi: 10.2746/042516408X295464
Rötting AK, Freeman DE, Constable PD, Moore RM, Eurell JC, Wallig MA, Hubert JD.Eosinophilic granulocytes have been associated with parasite or immune-mediated diseases, but their functions in other disease processes remain unclear. Cause and timing of eosinophil migration into the equine gastrointestinal mucosa are also unknown. Objective: To determine the effects of intestinal parasitism on eosinophils in equine large intestinal mucosa. Methods: Large intestinal mucosal samples were collected from horses and ponies (n = 16) from the general veterinary hospital population, ponies (n = 3) raised in a parasite-free environment, ponies experimentally infected with 500 infec...
Massive pulmonary thromboembolism in six horses.
Equine veterinary journal    May 17, 2008   Volume 40, Issue 5 514-517 doi: 10.2746/042516408X297444
Norman TE, Chaffin MK, Perris EE, Edwards JF, David JB, Cohen ND, Reuss S.This report involves 6 cases in which medical records and post mortem findings were reviewed leading to the diagnosis of massive pulmonary thromboembolism (MPTE). All horses were mature and MPTE has not been recognised previously as a sequel to generalised systemic illness in mature horses. The clinical data and pathological findings of the cases are reported and the authors conclude that MPTE is an uncommon but important complication of medical and surgical disorders in mature horses. In 3 of the cases, the condition was nonfatal suggesting that some horses having developed PTE survive and th...
Theriogenology question of the month.
Journal of the American Veterinary Medical Association    May 16, 2008   Volume 232, Issue 10 1473-1475 doi: 10.2460/javma.232.10.1473
Estrada A, Ferrer MS, Brounts SH, Milligan MA, Lillich JD, Debey B.No abstract available
Postpartum colic in a mare caused by pneumouterus.
The Veterinary record    May 16, 2008   Volume 162, Issue 19 626-627 doi: 10.1136/vr.162.19.626
Livesey LC, Carson RL, Stanton MB.No abstract available
Effects of altrenogest treatment of mares in late pregnancy on parturition and on neonatal viability of their foals. Neuhauser S, Palm F, Ambuehl F, Aurich C.In this study, effects of altrenogest treatment (0.088 mg/kg daily) given to mares during late gestation until parturition on the time and the process of foaling, neonatal adaptation and postnatal development were analysed. The number of animals was 6 in the treatment group and 7 in the control group. Gestational length tended to be shorter in mares given altrenogest. Birth weight of the foals and weight of the placenta did not differ between groups. The second stage of parturition was prolonged in the altrenogest-treated mares (p<0.05). Foals born to altrenogest-treated mares had a significan...
Immunophysiological responses of horses to a 12-hour rest during 24 hours of road transport.
The Veterinary record    May 16, 2008   Volume 162, Issue 19 609-614 doi: 10.1136/vr.162.19.609
Stull CL, Morrow J, Aldridge BA, Stott JL, McGlone JJ.Thirty-eight mature horses were assigned to one of two equal groups to evaluate two treatments consisting of either 24 hours of continuous road transport (24T) or two 12-hour periods of transport separated by off-loading, resting and feeding the horses for 12 hours (12/12T). A subset of six horses from each group served as controls for the other group. The horses were loaded into a commercial straight-deck trailer and travelled loose in one of two standard-sized compartments. After the journeys the horses were put back into their paddocks for a 24-hour recovery period. Venous blood samples wer...
Gastrointestinal stromal tumour and hypoglycemia in a Fjord pony: case report.
Acta veterinaria Scandinavica    May 16, 2008   Volume 50, Issue 1 9 doi: 10.1186/1751-0147-50-9
Haga HA, Ytrehus B, Rudshaug IJ, Ottesen N.Neoplasia may cause hypoglycemia in different species including the horse, but hypoglycemia has not previously been reported in the horse associated with gastrointestinal stromal tumours. Methods: A case of a gastrointestinal stromal tumour in a Fjord pony with severe recurrent hypoglycemia is presented. The mechanism causing the hypoglycemia was not established. Conclusions: This case indicates that a gastrointestinal stromal tumour may cause hypoglycemia also in the horse.
[Construction of an infectious clone of equine infectious anemia virus by N-glycosylation reverse-mutations].
Wei sheng wu xue bao = Acta microbiologica Sinica    May 16, 2008   Volume 48, Issue 3 287-292 
Han X, Quan Y, Gao X, Xiang W, Zhou J.To elucidate the role of N-glycosylation in fetal donkey dermal cell (FDD)-attenuated equine infectious anemia virus (EIAV), we constructed an N-glycosylation reverse-mutation molecular clone, pLGN191N236N246. This viral molecular clone was derived from the infectious clone pLGFD3-8 by site-directed mutagenesis. This clone was used to transfect fetal donkey dermal (FDD) cells. Infectious characteristics of transfectants were monitored by RT-PCR, indirect immune fluorescence and reverse transcriptase activity assay. After three passages in FDD cells, viral replications in the supernatant of cel...
Intralesional injection of platelet-rich plasma followed by controlled exercise for treatment of midbody suspensory ligament desmitis in Standardbred racehorses.
Journal of the American Veterinary Medical Association    May 16, 2008   Volume 232, Issue 10 1515-1520 doi: 10.2460/javma.232.10.1515
Waselau M, Sutter WW, Genovese RL, Bertone AL.To determine outcome of Standardbred racehorses with moderate to severe midbody suspensory ligament desmitis (MSD) treated by means of ultrasound-guided intralesional injection of a single dose of platelet-rich plasma (PRP) followed by a program of gradually increased exercise. Methods: Nonrandomized clinical trial. Methods: 9 Standardbred racehorses. Methods: Following injection of PRP, horses were allowed a controlled, gradual return to exercise. Race records for the year prior to injury and for 3 consecutive years after horses returned to racing were reviewed. For comparison purposes, race ...
Spelt, an ancient cereal and first pressure linseed oil as ingredients of compound feedstuffs for modern horse feeding.
Journal of animal physiology and animal nutrition    May 15, 2008   Volume 92, Issue 3 303-309 doi: 10.1111/j.1439-0396.2007.00772.x
Fayt J, Dotreppe O, Hornick JL, Istasse L.Spelt is a covered cereal with large glumellas. In experiment 1, it has been compared in terms of chemical composition with barley, oat and maize. Spelt is characterized by rather low protein and ether extract (EE) contents. The neutral detergent fibre (NDF) content of spelt was slightly higher than that of oat but the acid detergent fibre (ADF) content was lower. Two compound feedstuffs were fed along with hay to six horses used in a cross-over design. Both diets were well appreciated by the horses and there were no significant differences in the apparent digestibility coefficients, except fo...
Micro-computed tomography of early lesions of osteochondrosis in the tarsus of foals.
Bone    May 15, 2008   Volume 43, Issue 3 574-583 doi: 10.1016/j.bone.2008.04.024
Olstad K, Cnudde V, Masschaele B, Thomassen R, Dolvik NI.Osteochondrosis (OC) is an important developmental orthopedic disease of human and equine patients. The disease is defined as a focal disturbance in enchondral ossification. In horses, the disturbance can occur secondary to failure of the blood supply to growth cartilage. Diagnosis of the early, subclinical stages that can clarify the etiology is currently confined to cross-sectional histological examination. The potential for micro-computed tomography (micro-CT) with angiography to detect early lesions of OC has not yet been investigated. Methods: Nine Standardbred foals bred from parents wit...
Hepatic diseases in horses.
Journal of animal physiology and animal nutrition    May 15, 2008   Volume 92, Issue 3 345-355 doi: 10.1111/j.1439-0396.2007.00798.x
Bergero D, Nery J.The concept 'liver disease' includes several pathological conditions affecting liver's functions. It can either consist of a temporary impaired functioning of the liver and/or it can progress to its failure. The purpose of this review is to update the knowledge on hepatobiliary diseases and in particular on equine hyperlipaemia. Hepatobiliary disease's aetiology, clinical signs, diagnosis and nutritional management are thus described in the first part of the review the second part being devoted to hyperlypaemia's lipid metabolism, epidemiology, clinical signs, post-mortem observations and nutr...
Peripheral blood mononuclear cells represent a reservoir of bovine papillomavirus DNA in sarcoid-affected equines.
The Journal of general virology    May 14, 2008   Volume 89, Issue Pt 6 1390-1395 doi: 10.1099/vir.0.83568-0
Brandt S, Haralambus R, Schoster A, Kirnbauer R, Stanek C.Bovine papillomaviruses of types 1 and 2 (BPV-1 and -2) chiefly contribute to equine sarcoid pathogenesis. However, the mode of virus transmission and the presence of latent infections are largely unknown. This study established a PCR protocol allowing detection of <or=10 copies of the BPV-1/-2 genes E5 and L1. Subsequent screening of peripheral blood mononuclear cell (PBMC) DNA derived from horses with and without BPV-1/2-induced skin lesions demonstrated the exclusive presence of E5, but not L1, in PBMCs of BPV-1/2-infected equines. To validate this result, a blind PCR was performed from ...
Dermatophytoses in animals.
Mycopathologia    May 14, 2008   Volume 166, Issue 5-6 385-405 doi: 10.1007/s11046-008-9102-7
Chermette R, Ferreiro L, Guillot J.Dermatophytoses are one of the most frequent skin diseases of pets and livestock. Contagiousness among animal communities, high cost of treatment, difficulty of control measures, and the public health consequences of animal ringworm explain their great importance. A wide variety of dermatophytes have been isolated from animals, but a few zoophilic species are responsible for the majority of the cases, viz. Microsporum canis, Trichophyton mentagrophytes, Trichophyton equinum and Trichophyton verrucosum, as also the geophilic species Microsporum gypseum. According to the host and the fungal spec...
Full-length and internally deleted forms of interleukin-7 are present in horse (Equus caballus) lymph node tissue.
Veterinary immunology and immunopathology    May 14, 2008   Volume 125, Issue 1-2 126-134 doi: 10.1016/j.vetimm.2008.05.006
Cook RF, Cook SJ, Even DL, Schaffer C, Issel CJ.Horse IL-7 (HIL-7) cDNA was isolated from adult lymph node tissue by reverse transcription polymerase chain reaction (RT-PCR) using oligonucleotide primers based on horse genomic sequences (The Broad Institute). In addition, to the full-length (FL) 531bp reading frame encoding 176 amino acids, shorter open-reading frames of 477, 396 and 264bp were also amplified. Nucleotide sequence analysis of these RT-PCR products demonstrated they were homologous except the shorter species were missing internal sequences consistent with multiple RNA splicing events. Consequently, the shorter open-reading fr...
Simulated digest of a glucosamine-based equine nutraceutical modifies effect of IL-1 in a cartilage explant model of inflammation.
Journal of veterinary pharmacology and therapeutics    May 13, 2008   Volume 31, Issue 3 268-271 doi: 10.1111/j.1365-2885.2008.00946.x
Pearson W, Lindinger MI.No abstract available
Proceedings of the 5th International Symposium on Stallion Reproduction. Gramado, Rio Grande do Sul, Brazil.
Animal reproduction science    May 13, 2008   Volume 107, Issue 3-4 177-360 doi: 10.1016/j.anireprosci.2008.05.005
No abstract available
The effects of cryptorchidism on the regulation of steroidogenesis and gap junctional communication in equine testes.
Endokrynologia Polska    May 10, 2008   Volume 59, Issue 2 112-118 
Hejmej A, Bilińska B.Evidence collected over the years has demonstrated that cryptorchidism is associated with a defect in spermatogenesis and, as a consequence, with either reduced fertility or infertility. However, the effect of cryptorchidism on Leydig cell function is less clear. The aim of our study therefore was to investigate the regulation of steroid hormone biosynthesis and, additionally, intercellular communication in the cryptorchid equine testes. Methods: Testes of mature bilaterally cryptorchid horse and healthy stallions were used for this study. The expression of luteinising hormone receptor (LHR), ...