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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Characterization of the in vitro responses of equine cecal longitudinal smooth muscle to endothelin-1.
American journal of veterinary research    August 23, 2005   Volume 66, Issue 7 1202-1208 doi: 10.2460/ajvr.2005.66.1202
Chidambaram RM, Eades SC, Moore RM, Hosgood G, Venugopal CS.To characterize the in vitro response of equine cecal longitudinal smooth muscle (CLSM) to endothelin (ET)-1 and assess the role of ETA and ETB receptors in those ET-1-induced responses. Methods: 36 horses without gastrointestinal tract disease. Methods: To determine cumulative concentration-response relationships, CLSM strips were suspended in tissue baths containing graded concentrations of ET-1 (10(-9) to 10(-6)M) with or without BQ-123 (ETA receptor antagonist); with or without IRL-1038 (ETB receptor antagonist); or with both antagonists at concentrations of 10(-9), 10(-7), and 10(-5)M. To...
French field results (1985-2005) on factors affecting fertility of frozen stallion semen.
Animal reproduction science    August 23, 2005   Volume 89, Issue 1-4 115-136 doi: 10.1016/j.anireprosci.2005.07.003
Vidament M.Results on procedures for freezing stallion semen and the subsequent fertility during 20 years are presented. The present system applied in French National Stud includes: (1) a freezing protocol (dilution in milk, centrifugation and addition of freezing extender (INRA82+egg yolk (2%, v/v)+glycerol (2.5%, v/v) at 22 degrees C, a moderate cooling rate to 4 degrees C and freezing at -60 degrees C/min in 0.5-ml straws); (2) selection of ejaculates showing post-thaw rapid motility >35%; and (3) an insemination protocol (mares examined once daily, two AI of 400 x 10(6) spermatozoa 24 h apart before ...
Effects of training on potassium homeostasis during exercise and skeletal muscle Na+,K(+)-ATPase concentration in young adult and middle-aged Dutch Warmblood horses.
American journal of veterinary research    August 23, 2005   Volume 66, Issue 7 1252-1258 doi: 10.2460/ajvr.2005.66.1252
Suwannachot P, Joosten BJ, Klarenbeek A, Hofma J, Enzerink E, van Weeren PR, Everts ME.To investigate the effects of moderate short-term training on K+ regulation in plasma and erythrocytes during exercise and on skeletal muscle Na+,K(+)-ATPase concentration in young adult and middle-aged horses. Methods: Four 4- to 6-year-old and four 10- to 16-year-old Dutch Warmblood horses. Methods: The horses underwent a 6-minute exercise trial before and after 12 days of training. Skeletal muscle Na+,K(+)-ATPase concentration was analyzed in gluteus medius and semitendinosus muscle specimens before and after the 12-day training period. Blood samples were collected before and immediately af...
Quantitative comparison of three commonly used treatments for navicular syndrome in horses.
American journal of veterinary research    August 23, 2005   Volume 66, Issue 7 1247-1251 doi: 10.2460/ajvr.2005.66.1247
Schoonover MJ, Jann HW, Blaik MA.To quantitatively compare 3 commonly used treatments for navicular syndrome (NS) in horses: heel-elevation shoeing alone, heel-elevation shoeing and phenylbutazone administration, heel-elevation shoeing and injection of the distal interphalangeal joint (DIPJ) with triamcinolone acetonide (TA), and all 3 treatments in combination. Methods: 12 horses with NS. Methods: A force plate was used to measure baseline peak vertical ground reaction force (PVGRF) of the forelimbs. Each horse's forelimbs were shod with 3 degrees heel-elevation horseshoes; PVGRF was measured 24 hours and 14 days after shoei...
Influence of age, site, and degenerative state on the speed of sound in equine articular cartilage.
American journal of veterinary research    August 23, 2005   Volume 66, Issue 7 1175-1180 doi: 10.2460/ajvr.2005.66.1175
Brommer H, Laasanen MS, Brama PA, van Weeren PR, Barneveld A, Helminen HJ, Jurvelin JS.To determine the speed of sound (SOS) in equine articular cartilage and investigate the influence of age, site in the joint, and cartilage degeneration on the SOS. Methods: Cartilage samples from 38 metacarpophalangeal joints of 38 horses (age range, 5 months to 22 years). Methods: Osteochondral plugs were collected from 2 articular sites of the proximal phalanx after the degenerative state was characterized by use of the cartilage degeneration index (CDI) technique. The SOS was calculated (ratio of needle-probe cartilage thickness to time of flight of the ultrasound pulse), and relationships ...
Aversive conditioning of periodic spontaneous erection adversely affects sexual behavior and semen in stallions.
Animal reproduction science    August 23, 2005   Volume 89, Issue 1-4 77-92 doi: 10.1016/j.anireprosci.2005.06.016
McDonnell SM, Hinze AL.Periodic spontaneous erection and penile movements known as masturbation (SEAM) occur normally at approximately 90 min intervals in awake equids. SEAM in horses has traditionally been misunderstood by many horsemen as aberrant behavior that should be eliminated. Accordingly, it is not uncommon for trainers of performance stallions or managers of breeding stallions to punish SEAM in an attempt to eliminate the behavior. Previous clinical observations and preliminary unsystematic trials had suggested that attempts to stop stallion SEAM may lead to an increase rather than a decrease in SEAM, and ...
Comparison of intraosseous and intravenous infusion of technetium Tc 99m pertechnate in the distal portion of forelimbs in standing horses by use of scintigraphic imaging.
American journal of veterinary research    August 23, 2005   Volume 66, Issue 7 1267-1272 doi: 10.2460/ajvr.2005.66.1267
Mattson SE, Pearce SG, Bouré LP, Dobson H, Hurtig MB, Black WD.To describe and compare the distribution of technetium Tc 99m (99mTc) pertechnate following intraosseous or i.v. injection (with or without use of a tourniquet) in the distal portion of the forelimb in standing horses. Methods: 4 horses. Methods: Each horse received 4 forelimb treatments in random sequence: intraosseous infusion with tourniquet application (IOT), intraosseous infusion without tourniquet application, i.v infusion with tourniquet application (IVT), and i.v. infusion without tourniquet application. Dynamic nuclear scintigraphic imaging of the third metacarpal bone, proximal and m...
Biochemical analysis of the articular cartilage and subchondral and trabecular bone of the metacarpophalangeal joint of horses with early osteoarthritis.
American journal of veterinary research    August 23, 2005   Volume 66, Issue 7 1238-1246 doi: 10.2460/ajvr.2005.66.1238
van der Harst MR, DeGroot J, Kiers GH, Brama PA, van de Lest CH, van Weeren PR.To assess whether site-related changes in biochemical composition are present in the cartilage and subchondral and trabecular bone of the metacarpophalangeal joint of horses with early osteoarthritis. Methods: Right metacarpophalangeal joints from 59 mature warmblood horses. Methods: Biochemical data (cross-link, amino acid, DNA, and ash contents; denatured collagen and glycosaminoglycan [GAG] concentrations; bone mineral density; and mineral composition) were obtained from 2 differently loaded sites of phalanx I cartilage and subchondral and trabecular bone samples; data were compared with pr...
Effects of tension of the girth strap on respiratory system mechanics in horses at rest and during hyperpnea induced by administration of lobeline hydrochloride.
American journal of veterinary research    August 23, 2005   Volume 66, Issue 7 1167-1174 doi: 10.2460/ajvr.2005.66.1167
Hoffman AM, Swanson LG, Bruns SJ, Kuehn H, Bedenice D.To determine whether tension of the girth strap of a saddle would sufficiently affect rib motion and reduce lung volume to alter pulmonary resistance in horses. Methods: 10 healthy adult horses. Methods: We used classical techniques to measure the effects of tightening a girth strap (15 kg of tension) on pulmonary dynamics during eupnea and hyperpnea in horses. Respiratory impedance was evaluated by use of oscillometry, and resistance and reactance data were partitioned into lung and chest wall components. Rib cage and abdominal contributions to tidal volume and minute ventilation were measure...
Effect of a silicone-containing dressing on exuberant granulation tissue formation and wound repair in horses.
American journal of veterinary research    August 23, 2005   Volume 66, Issue 7 1133-1139 doi: 10.2460/ajvr.2005.66.1133
Ducharme-Desjarlais M, Céleste CJ, Lepault E, Theoret CL.To determine the effect of a silicone dressing on the rate and quality of repair of limb wounds and compare microvascular occlusion and apoptosis in wounds treated with the silicone dressing and those treated with a conventional dressing in horses. Methods: 5 horses. Methods: Horses received two 6.25-cm2 wounds on each metacarpus. Ten wounds were treated with a silicone dressing; the other 10 were treated with a control dressing. Quality of repair and wound size were evaluated at each bandage change. Time to healing and the number of excisions of exuberant granulation tissue were recorded. Bio...
Molecular cloning and characterization of markers and cytokines for equid myeloid cells.
Veterinary immunology and immunopathology    August 23, 2005   Volume 108, Issue 1-2 227-236 doi: 10.1016/j.vetimm.2005.07.015
Steinbach F, Stark R, Ibrahim S, Gawad EA, Ludwig H, Walter J, Commandeur U, Mauel S.The myeloid cell system comprises of monocytes, macrophages (MPhi), dendritic cells (DC), Kupffer cells, osteoclasts or microglia and is also known as the mononuclear phagocytic system (MPS). Essential cytokines to differentiate or activate these cells include GM-CSF or IL-4. Important markers for characterization include CD1, CD14, CD68, CD163 and CD206. All these markers, however, were not cloned or further characterized in equids by use of monoclonal antibodies earlier. To overcome this problem with the present study, two approaches were used. First, we cloned equine cytokines and markers, ...
Aspergillosis in mammals and birds: impact on veterinary medicine.
Medical mycology    August 23, 2005   Volume 43 Suppl 1 S71-S73 doi: 10.1080/13693780400020089
Tell LA.Aspergillosis is relatively uncommon in mammals, but dogs, horses, cows and dolphins are susceptible. On the other hand, aspergillosis is a major cause of mortality in birds. This paper provides an overview of the manifestations of this disease in these animals. Treatment options are still lacking, but the increased incidence of the disease in humans has led to increased study, which may benefit both human and veterinary medicine.
Comparative biochemical analyses of venous blood and peritoneal fluid from horses with colic using a portable analyser and an in-house analyser.
The Veterinary record    August 23, 2005   Volume 157, Issue 8 217-223 doi: 10.1136/vr.157.8.217
Saulez MN, Cebra CK, Dailey M.Fifty-six horses with colic were examined over a period of three months. The concentrations of glucose, lactate, sodium, potassium and chloride, and the pH of samples of blood and peritoneal fluid, were determined with a portable clinical analyser and with an in-house analyser and the results were compared. Compared with the in-house analyser, the portable analyser gave higher pH values for blood and peritoneal fluid with greater variability in the alkaline range, and lower pH values in the acidic range, lower concentrations of glucose in the range below 8.3 mmol/l, and lower concentrations of...
Temporal folate status during lactation in mares and growth in foals.
American journal of veterinary research    August 23, 2005   Volume 66, Issue 7 1214-1221 doi: 10.2460/ajvr.2005.66.1214
Ordakowski-Burk AL, Kronfeld DS, Williams CA, Gay LS, Sklan DJ.To identify changes in folate status of mares and foals during lactation and growth, respectively. Methods: 20 Thoroughbred mares and foals. Methods: Pregnant mares, and following foaling the same mares with their foals, were maintained on mixed grass-legume pasture and fed either a traditional dietary supplement rich in sugar and starch (SS) or a dietary supplement high in fat and fiber (FF). Blood samples were collected monthly from mares and foals up to 6 months after foaling. Total folate concentration in feed and forage was determined. Analyses of plasma folate, RBC folate, plasma homocys...
Epidemic West Nile virus encephalomyelitis: a temperature-dependent, spatial model of disease dynamics.
Preventive veterinary medicine    August 22, 2005   Volume 71, Issue 3-4 253-264 doi: 10.1016/j.prevetmed.2005.07.008
Ward MP.Since first being detected in New York in 1999, West Nile virus (WNV) has spread throughout the United States and more than 20,000 cases of equine WNV encephalomyelitis have been reported. A spatial model of disease occurrence was developed, using data from an outbreak of serologically confirmed disease in an unvaccinated population of horses at 108 locations in northern Indiana between 3 August and 17 October 2002. Daily maximum temperature data were recorded at meteorological stations surrounding the study area. The distribution of the total number of degree-days elapsing between July 4 and ...
Extracellular matrix composition of the equine superficial digital flexor tendon: relationship with age and anatomical site.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine    August 20, 2005   Volume 52, Issue 7 333-338 doi: 10.1111/j.1439-0442.2005.00742.x
Lin YL, Brama PA, Kiers GH, van Weeren PR, DeGroot J.The objectives of the present study were to test the hypotheses that: (1) the composition of the extracellular matrix of the equine superficial digital flexor tendon (SDFT) shows great functional similarities with articular cartilage, i.e. that significant differences exist in biochemical composition of differently loaded areas (which in the case of tendons may be more apparent as tendon shows more obvious differences than cartilage); and (2) that, as in articular cartilage, no substantial alterations in biochemical composition take place during ageing once adulthood has been attained. Tendon ...
Is snow a sufficient source of water for horses kept outdoors in winter? A case report.
Acta veterinaria Scandinavica    August 20, 2005   Volume 46, Issue 1-2 19-22 doi: 10.1186/1751-0147-46-19
Mejdell CM, Simensen E, Bøe KE.Due to extreme weather conditions, a flock of outwintered Icelandic horses had to manage for several days on snow as the source of free water. They were fed grass silage ad lib, and any change in feed consumption was not observed. After nine days, blood samples were taken and analysed for plasma osmolality, they were subjected to a simple clinical examination, and offered drinking water. Osmolality levels were within normal limits and mean value did not differ significantly from samples which previously were taken of the same individuals. The general condition of the horses was normal, with no...
Genetic variation of Polish endangered Biłgoraj horses and two common horse breeds in microsatellite loci.
Journal of applied genetics    August 20, 2005   Volume 46, Issue 3 299-305 
Zabek T, Nogaj A, Radko A, Nogaj J, Słota E.Genetic variation of endangered Biłgoraj horses and two common Polish horse breeds was compared with the use of 12 microsatellite loci (AHT4, AHT5, ASB2, HMS2, HMS3, HMS6, HMS7, HTG4, HTG6, HTG7, HTG10, VHL20). Lower allelic diversity was detected in all investigated populations in comparison to other studies. Large differences in the frequencies of microsatellite alleles between Biłgoraj horses and two other horse breeds were discovered. In all polymorphic loci all investigated breeds were in the Hardy-Weinberg equilibrium. Mean Fis values and the results of a test for the presence of a rec...
An investigation of the ability of the glutaraldehyde test to distinguish between acute and chronic inflammatory disease in horses.
Acta veterinaria Scandinavica    August 20, 2005   Volume 46, Issue 1-2 69-78 doi: 10.1186/1751-0147-46-69
Brink P, Wright JC, Schumacher J.The glutaraldehyde test (GT), a rapid and inexpensive test, has been utilized empirically for many years in bovine practice for diagnosing inflammatory diseases. GT is used primarily to demonstrate increased serum concentrations of fibrinogen and globulin. Glutaraldehyde binds with free amino groups in fibrinogen and immunoglobulin to create a clot in a first degree chemical reaction. The clotting time of the GT estimates the content of proteins produced in response to inflammation. The applicability of GT for diagnosing inflammation in the horse has never been investigated. The objective of t...
Datura contamination of hay as the suspected cause of an extensive outbreak of impaction colic in horses.
Journal of the South African Veterinary Association    August 20, 2005   Volume 76, Issue 2 107-112 doi: 10.4102/jsava.v76i2.407
Naudé TW, Gerber R, Smith RJ, Botha CJ.Datura poisoning of horses is extensively reviewed. An outbreak of intractable impaction colic affecting 18 of 83 horses was stopped by withdrawing dried tef hay contaminated with young Datura plants. The dried, botanically identified Datura stramonium and D. ferox contained respectively 0.15% mass/mass (m/m) hyoscyamine as well as 0.16% m/m hyoscine (scopolamine) and only hyoscine at a concentration of 0.11% m/m. Immature, unidentifiable plants resembling D. stramonium, contained 0.14% m/m and 0.12% m/m of the 2 respective tropane alkaloids. The outbreak was characterised by protracted and re...
Tracheal perforation managed by temporary tracheostomy in a horse.
Journal of the South African Veterinary Association    August 20, 2005   Volume 76, Issue 2 113-115 doi: 10.4102/jsava.v76i2.408
Saulez MN, Slovis NM, Louden AT.Tracheal trauma with resultant rupture is uncommonly reported in veterinary literature. We report the case of a 16-year-old Thoroughbred gelding that sustained a 1 cm longitudinal perforation of the dorsal tracheal membrane in the proximal cervical region. The horse subsequently developed dyspnoea due to acute upper respiratory obstruction secondary to severe emphysema of the guttural pouches. A temporary tracheostomy caudal to the site of tracheal perforation was performed under local anaesthesia. This procedure helped relieve the upper airway obstruction and aided resolution of the injury by...
Mechanical horseback riding improves insulin sensitivity in elder diabetic patients.
Diabetes research and clinical practice    August 18, 2005   Volume 71, Issue 2 124-130 doi: 10.1016/j.diabres.2005.06.012
Kubota M, Nagasaki M, Tokudome M, Shinomiya Y, Ozawa T, Sato Y.The present study was undertaken to analyze the acute and chronic effects of exercise on insulin sensitivity in elder diabetic patients using a horseback riding therapeutic equipment (Joba). The acute effects of exercise were examined by means of a single session of Joba riding that lasted for 30 min. The average glucose infusion rates (GIR) before and during exercise were regarded as an index of the insulin action in peripheral tissues by the euglycemic clamp. The chronic effects of exercise were studied by training the elder diabetic patients for 12 weeks using the Joba apparatus. The insuli...
Antibodies and PMBC from EIAV infected carrier horses recognize gp45 and p26 synthetic peptides.
Veterinary immunology and immunopathology    August 18, 2005   Volume 108, Issue 3-4 335-343 doi: 10.1016/j.vetimm.2005.06.007
Soutullo A, García MI, Bailat A, Racca A, Tonarelli G, Malan Borel I.Equine infectious anemia virus (EIAV) is a lentivirus causing a persistent infection in horses characterized by recurrent febrile episodes and high levels of viremia associated with a novel antigenic strain of the virus. The virus contains two envelope glycoproteins, gp90 and gp45, and four internal proteins, p26, p15, p11 and p9. Considering that the most infected horses are able to restrict EIAV replication to very low levels and that gp45 and p26 contain highly conserved epitopes among lentiviruses, it would be necessary to identify those conserved epitopes stimulating cellular and humoral ...
Comparative morphological study on the tongue and lingual papillae of horses (Perissodactyla) and selected ruminantia (Artiodactyla).
Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia    August 17, 2005   Volume 110, Issue 2 Suppl 1 55-63 
Kobayashi K, Jackowiak H, Frackowiak H, Yoshimura K, Kumakura M, Kobayashi K.A common characteristic of horses, Rocky Mountain goats, and cattle is that they all have a well developed lingual prominence on the dorsal surface of the posterior area of the tongue. Foliate papillae were found in the horse studied but not in the goat or in cattle. The horse filiform papillae had a long and slender external form with a thin and slender CTC, while in the goat and cattle the external form consisted of a large thick main process and the CTC consisted of a bundle of numerous rod-shaped protrusions. The special papilla found on the lingual prominence resembled larger filiform-lik...
Reticulocyte changes after experimental anemia and erythropoietin treatment of horses.
Journal of applied physiology (Bethesda, Md. : 1985)    August 17, 2005   Volume 99, Issue 3 915-921 doi: 10.1152/japplphysiol.00438.2005
Cooper C, Sears W, Bienzle D.Availability of recombinant human erythropoietin (EPO) has facilitated use to enhance red blood cell production, and therefore aerobic performance, in human and equine athletes. Recombinant human EPO promotes growth and differentiation of equine erythroid precursor cells, but in some horses repeat administration induces immune interference with endogenous EPO resulting in fatal anemia. Although blood reticulocyte parameters acquire unique changes in humans treated with EPO, with manual enumeration methods, horses were not considered to release reticulocytes from the bone marrow into circulatio...
Proceedings of the 4th International Symposium on Stallion Reproduction, Hannover, Germany, October 2005.
Animal reproduction science    August 17, 2005   Volume 89, Issue 1-4 1-321 doi: 10.1016/j.anireprosci.2005.07.006
No abstract available
Carpal collateral ligament desmopathy in three horses.
The Veterinary record    August 16, 2005   Volume 157, Issue 7 197-201 doi: 10.1136/vr.157.7.197
Desmaizières LM, Cauvin ER.The radiographic and ultrasonographic findings in three horses with severe damage to the collateral ligaments of the carpus, associated with degenerative joint disease, are described. The horses remained lame despite prolonged rest and medical management, primarily because of the progression of the joint disease. Ultrasonography was found to be an accurate method for diagnosing the injury to the ligaments and is recommended as part of a routine examination in suspected carpal injuries.
IgA Fc receptors in cattle and horses.
Veterinary immunology and immunopathology    August 16, 2005   Volume 108, Issue 1-2 139-143 doi: 10.1016/j.vetimm.2005.07.008
Morton HC.The biological role of IgA depends, at least partly, on the interaction with specific receptors (FcalphaRs) on the surface of leukocytes. The human FcalphaR, CD89, was the first IgA Fc receptor to be identified, and binding of IgA-coated particles to CD89 triggers numerous cellular effector functions including phagocytosis, antibody-dependent cell-mediated cytotoxicity (ADCC), and release of inflammatory mediators. Recently, CD89 orthologs have been identified in a number of other species, including cows and horses. This brief review will summarize our current knowledge regarding the structure...
Temporal regulation of cytokine mRNA expression in equine recurrent airway obstruction.
Veterinary immunology and immunopathology    August 16, 2005   Volume 108, Issue 1-2 237-245 doi: 10.1016/j.vetimm.2005.07.013
Horohov DW, Beadle RE, Mouch S, Pourciau SS.Acute and chronic inflammation of the airway remains an important health problem for equids. "Heaves" or recurrent airway obstruction (RAO) remains one of the most commonly diagnosed conditions affecting the lung of older horses in Europe and the United States. The typical clinical signs of RAO include non-productive coughing, serous nasal discharge, labored expiratory effort, and flaring of the nostrils. Auscultation of the lungs of the affected horse often reveals abnormal respiratory sounds, described as crackles and wheezes, throughout the area of the lung field. These clinical signs occur...
Phylogenetic relationships of Sarcocystis neurona of horses and opossums to other cyst-forming coccidia deduced from SSU rRNA gene sequences.
Parasitology research    August 16, 2005   Volume 97, Issue 5 345-357 doi: 10.1007/s00436-005-1396-5
Elsheikha HM, Lacher DW, Mansfield LS.Phylogenetic analyses based on sequences of the nuclear-encoded small subunit rRNA (ssurRNA) gene were performed to examine the origin, phylogeny, and biogeographic relationships of Sarcocystis neurona isolates from opossums and horses from the State of Michigan, USA, in relation to other cyst-forming coccidia. A total of 31 taxa representing all recognized subfamilies and genera of Sarcocystidae were included in the analyses with clonal isolates of two opossum and two horse S. neurona. Phylogenies obtained by the four tree-building methods were consistent with the classical taxonomy based on ...