Omneity® Pellets
All-In-One Vitamin & Mineral Pellet
Topic:Equine Science
Equine Science encompasses the study of horses and their management, health, and performance. This field integrates various scientific disciplines such as biology, genetics, nutrition, physiology, and veterinary medicine to understand and improve the well-being and capabilities of horses. Areas of focus include equine anatomy, reproduction, behavior, and disease prevention. Research in equine science aims to enhance horse care, optimize training and performance, and address health challenges. This page compiles peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine science, providing insights into the latest advancements and methodologies in the field.
Utilisation of the time constant calculated from heart rate recovery after exercise for evaluation of autonomic activity in horses. Heart rate (HR) recovery immediately after exercise is controlled by autonomic functions and the time constant (T) calculated from HR recovery is thought to be an index of parasympathetic activity in man. Objective: To investigate whether it is possible to evaluate autonomic function using the time constant in horses. Methods: Five Thoroughbred horses were subjected to a standard exercise test. Following pre-medication with saline, atropine and/or propranolol, the horses ran for 2.5 min at a speed of 8 m/sec at a 10% incline and T was calculated from HR after the exercise. Secondly, 7 Thorough...
Effects of short-term training on insulin sensitivity and skeletal muscle glucose metabolism in standardbred horses. Increased insulin sensitivity occurs after a period of exercise training, but the mechanisms underlying this training-associated increase in insulin action have not been investigated. Objective: To examine the effects of short-term endurance training (7 consecutive days) and a subsequent period of inactivity (5 days) on whole body insulin sensitivity and GLUT-4 protein and the activities of glycogen synthase (GS) and hexokinase (HK) in skeletal muscle. It was hypothesised that training would increase insulin sensitivity in association with increased GLUT-4 protein and activities of GS and HK, ...
The effect of gallop training on hoof angle in thoroughbred racehorses. The economic impact of soundness problems in racehorses is very high and low hoof angle at the toe has been associated with a lack of soundness. However, it is not clear what environmental and management factors might contribute to a low hoof angle. Objective: To investigate the hypothesis that the hooves of racehorses become flatter when in gallop training, as well as to determine factors contributing to this trend. Methods: Weekly hoof measurements were taken with a hoof gauge from 45 Thoroughbred racehorses; 4 Thoroughbred show horses kept in consistent conditions and shod by the same farri...
A nonsurgical method allowing continuous core temperature monitoring in mares for extended periods, including during endurance exercise. Body temperature can be a useful measure of how well the horse responds to thermal challenges of exercise and environment. Currently there is little information available about how body temperature changes throughout an endurance ride, and no nonsurgical methods to evaluate internal temperature of exercising horses during prolonged periods and during long distances. Objective: To develop and test a nonsurgical method, using temperature loggers, of continuously recording internal temperature during exercise and over an extended period. Methods: Loggers were inserted transcervically into the ute...
Effects of dietary energy source and physical conditioning on insulin sensitivity and glucose tolerance in standardbred horses. There is evidence that adaptation to diets rich in nonstructural carbohydrates (NSC) contributes to the development of insulin resistance in horses. To date, however, no study in horses has examined the effects of physical conditioning on diet-associated alterations in insulin sensitivity and glucose tolerance. Objective: To examine the effects of adaptation to concentrate feeds rich in NSC or fat on insulin sensitivity and glucose tolerance in horses, both in the sedentary state and after a subsequent period of physical conditioning. Methods: Fourteen mature Standardbred horses underwent both...
Correlation of race earnings with velocity at maximal heart rate during a field exercise test in thoroughbred racehorses. Running ability of Thoroughbred racehorses is correlated with maximal oxygen uptake, and the velocity at maximal oxygen uptake is highly correlated with the velocity at maximal heart rate (VHRmax). Objective: To investigate the relationship between VHRmax and racing performance, expressed as 'peak dollars earned per race start'. Methods: Heart rate (HR) and velocity were recorded in 25 Thoroughbred racehorses during trotting and subsequent fast gallops in the field at velocities of 15-16 m/sec. Velocity was recorded by a global positioning system (GPS). Maximal HR (HRmax) and maximal velocity ...
An echocardiographic and auscultation study of right heart responses to training in young national hunt thoroughbred horses. There are few data available to determine the effect of training on cardiac valve function. Objective: To investigate the effect of commercial race training on right ventricular (RV) and tricuspid valve function in an untrained group of National Hunt Thoroughbreds (TB). Methods: Cardiac auscultation, guided M-mode echocardiography of the RV, and colour flow Doppler (CFD) tricuspid valve and right atrium were performed in 90 TB horses (age 2-7 years) 1998-2003. Forty horses were examined at least once and 48 horses were examined on at least 2 occasions. Examinations were then classified as: i) ...
Is the distribution of selenium and zinc in the sublocations of spermatozoa regulated? In the sperm nuclei, of mammalian species selenium has been found only in the form of sperm nuclei glutathione peroxidase (snGPx) where it is most likely bound to the chromatin of spermatozoa. Over 80% of selenium in sperm is bound to the selenoprotein phospholipid hydroperoxide glutathione peroxidase (PHGPx) in the midpiece of rat sperm. Zinc in sperm is mainly contained in the outer dense fiber (ODF) proteins of the flagella of mammalian spermatozoa. In the sperm nuclei, zinc is predominately located in the chromatin to the protamine proteins. In order to investigate if the insertion of zinc...
The effect of long-term exercise on glucose metabolism and peripheral insulin sensitivity in standardbred horses. To study the possible long-term effect of improved glucose tolerance in horses after long-term training, as the impact of exercise training on glucose metabolism is still unclear in the equine species. It is not known whether there is a direct long-term effect of training or if the measurable effect on glucose metabolism is the residual effect of the last exercise session. Objective: To determine the chronic effect on glucose metabolism and peripheral insulin sensitivity of long-term training in horses by use of the euglycaemic hyperinsulinaemic clamp technique. Methods: Eleven Standardbred ho...
Does usefulness of potassium supplementation depend on speed? Electrolyte mixtures given to counter sweat loss usually contain abundant potassium. However, increases in plasma [K+] occur with exercise and supplementation may further increase plasma levels, potentially increasing the risk of neuromuscular hyperexcitability and development of adverse clinical sequellae. This proposition requires study. Objective: To compare effects of a K-rich electrolyte supplement (EM+K) to a K-free one (EM-K) on plasma [K+], [Ca++] and acid-base status during an endurance incremental exercise test on the treadmill. Methods: The test consisted of 3 bouts (simulating loop...
Effects of prior exercise on components of insulin signalling in equine skeletal muscle. Exercise is an important stimulus for the regulation of numerous metabolic functions in muscle, but there has been little investigation of the mechanism of exercise-enhanced glucose utilisation. Objective: To examine the effects of exercise on the signalling components Akt and glycogen synthase kinase-3 (GSK3) involved in insulin regulation of glycogen synthase (GS) activity. It was hypothesised that hyperinsulinaemia and prior exercise would alter the extent of Akt phosphorylation and GSK3beta deactivation and increase insulin stimulation of GS activity in skeletal muscle. Methods: Eight Stan...
Body composition in young standardbreds in training: relationships to body condition score, physiological and locomotor variables during exercise. Body composition is an essential factor in athletic performance of human sprinters and long distance runners. However, in horses, many questions remain concerning relationships between body composition and performance in the different equine activities. Objective: To determine relationships between body composition, body score, physiological and locomotor variables in a population of young Standardbreds in training. Methods: Twenty-four 2-year-old Standardbreds were studied, body condition on a scale 0-5 and bodyweight recorded, and height at withers measured. Percentage of fat (%F), fat mass ...
Exercise-induced pulmonary haemorrhage during submaximal exercise. Maximally exercising horses achieve mean pulmonary artery pressures (Ppa(mean)) that exceed the minimum threshold (75 mmHg) estimated for pulmonary capillary rupture and exercise-induced pulmonary haemorrhage (EIPH). EIPH is not expected to occur during moderate submaximal exercise (i.e. 40-60% VO2max) since Ppa(mean) remains well below this threshold. Objective: Prolonged submaximal exercise (trotting) would precipitate locomotory respiratory uncoupling and cause EIPH. This would be present as a result of the most negative intrapleural pressures (as estimated by the minimum oesophageal pressu...
The effect of physical exercise on the daily rhythm of platelet aggregation and body temperature in horses. The goal of this study was to investigate the influence of physical activity on the daily rhythm of platelet aggregation and body temperature in horses. Blood samples from 12 Thoroughbred horses, six sedentary animals and six athletes (studied both before and after a period of inactivity) were collected at 4h intervals for 48h via an intravenous cannula inserted into the jugular vein. Body temperature was recorded every 4h for 48h with a rectal probe. Platelet aggregation was measured with an aggregometer. Collagen was used to test the aggregation of the plasma samples. Statistical analysis of...
Inbreeding and genetic structure in the endangered Sorraia horse breed: implications for its conservation and management. The Sorraia horse is a closed breed with reduced effective population size and considered in critical maintained risk status. The breed exists in 2 main breeding populations, one in Portugal and one in Germany, with a smaller population size. A set of 22 microsatellite loci was used to examine genetic diversity and structure of the Sorraia horse breed and to compare individual inbreeding coefficient F, estimated from pedigree data, with individual heterozygosity and mean d(2). The Sorraia horse shows lower levels of microsatellite diversity when compared with other horse breeds. Due to managem...
Sexual behavior of mares. The mare is seasonally polyestrus, having an anovulatory period during the short light days of late fall and early winter, and beginning to ovulate as the days become longer during the winter. The complete estrus cycle is typically about 3 weeks, with 5 to 7 days of estrus and approximately 2 weeks of diestrus. When a mare lives within the natural social structure of the horse, i.e. a family band with several adult mares and one or more stallions, estrus is characterized by repeatedly approaching the stallion, frequent urination, deviating the tail away from the perineum, and standing still wi...
Molecular genetic analysis of the ATP2A2 gene as candidate for chronic pastern dermatitis in German draft horses. Chronic pastern dermatitis predominantly affects draft horses, and this condition is characterized by hyperkeratotic-hyperplastic dermal alterations. Chronic pastern dermatitis resembles the acral-hemorrhagic phenotype of Darier-White disease in humans. The ATP2A2 gene has been shown to be responsible for human Darier-White. Thus, we chose ATP2A2 on equine chromosome 8 (ECA8) as candidate for chronic pastern dermatitis in coldblood horses. A linkage analysis was performed in 10 paternal half-sib families consisting of 85 German coldblood horses using a microsatellite closely linked to ATP2A2, ...
Hypothermic storage of equine isolated hepatocytes. The aim of the study was to establish the optimal methods for hypothermic storage of equine isolated hepatocytes. Viability of equine isolated hepatocytes after hypothermic storage was dependent on the type of storage medium as well as on the cell density in the storage suspension and the preservation period. Hepatocytes stored at 4 degrees C in Hanks' Balanced Salt Solution (HBSS) and Williams' Medium E (WE) for 24 h showed very low viability, numerous cell membrane blebs, very low attachment rate (11.9 +/- 6.5% and 34.8 +/- 19.1%, respectively) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenylte...
Biogas production with horse dung in solid-phase digestion systems. Experiments on methanogenesis from horse dung were conducted in laboratory-scale batch reactors in order to determine the substrate performance in a solid-phase digestion process, more specifically in terms of potential energy recovery and suitable process technology. Dung from a horse stable with straw bedding was used. The temperature was kept in the mesophilic range. In the percolation process (with process water sprinkled over the stacked biomass) a proportion of 10-20% of solid inoculum (pre-digested horse dung) was found to be suitable. Comparative experiments with both percolation and f...
Management of equine poisoning and envenomation. Acute poisoning and envenomation often represent a diagnostic and therapeutic challenge. Although identification ultimately may benefit the affected animal, treatment frequently must commence before an etiologic diagnosis is established. Therefore, the goals for the management of acutely intoxicated horses must be focused on emergency intervention and stabilization of the patient, prevention of further exposure, and aggressive decontamination. This article reviews the treatment steps that should be considered during the management of horses experiencing poisoning or envenomation.
Neonatal foal resuscitation. Cardiac arrest in foals is generally secondary to other serious systemic diseases. Although it can often be anticipated, a clear plan is vital to success. Establishing cardiac output through chest compressions is the most important first step. This step should be followed by ventilation, drug therapy, identifying the nonperfusing cardiac rhythm, and following a preplanned treatment algorithm. Birth resuscitation requires special treatment considerations. The clinician should be prepared to perform resuscitation any time a birth is attended.
Mesenchymal stem cell therapy in equine musculoskeletal disease: scientific fact or clinical fiction? The goal in the therapeutic use of mesenchymal stem cells (MSCs) in musculoskeletal disease is to harness the regenerative nature of these cells focussing on their potential to grow new tissues and organs to replace damaged or diseased tissue. Laboratory isolation of MSCs is now well established and has recently been demonstrated for equine MSCs. Stem cell science has attracted considerable interest in both the scientific and clinical communities because of its potential to regenerate tissues. Research into the use of MSCs in tissue regeneration in general reflects human medical needs, however...
Oxidative stress. Oxidative stress refers to the cellular injury and pathologic change that occurs when there is an imbalance favoring oxidants over antioxidants within a living organism. In human medicine, oxidative stress has been implicated in numerous disease processes, which has led to further research into the clinical benefits and efficacy of antioxidant therapy. The evaluation of oxidative stress in the horse has been limited primarily to ischemia-reperfusion injury of the gastrointestinal tract, recurrent airway obstruction, exercise, osteoarthritis, equine motor neuron disease, and pituitary pars inte...
Ophthalmic emergencies in horses. The emergency clinician is frequently in the position of receiving, evaluating, and initiating treatment on horses with ophthalmic emergencies or orbital trauma. In the best of circumstances, an ophthalmologist is available to guide initial therapy and ultimately assume responsibility for the management of the patient during the remainder of its hospitalization, but this is not always the case. The information presented here is meant to provide the emergency clinician with basic guidelines for the initial assessment and management of horses sustaining ocular injuries or presented with an ophth...
The distribution of ganglion cells in the equine retina and its relationship to skull morphology. It has recently been reported that a strong correlation exists between the distribution of retinal ganglion cells and nose length in the domestic dog. To determine if this phenomenon occurs in another domestic species with diverse skull morphology, the current study examined the distribution of retinal ganglion cells in 30 horses from a variety of breeds. There was a significant variation in the density of ganglion cells found across the retinae. Breed was a significant predictor for ganglion cell density within the visual streak. A strong positive correlation exists between the density of gan...
