"Horses" is a broad topic that encompasses various aspects of equine biology, behavior, and management. This category includes studies on the anatomy, physiology, and genetics of horses, as well as their behavior, nutrition, and care. Research in this area may also cover the historical and cultural significance of horses, their roles in agriculture, sport, and therapy, and the challenges associated with their conservation and welfare. The page aggregates peer-reviewed research articles and scholarly studies that explore the multifaceted relationships between humans and horses, examining both scientific and socio-economic perspectives.
O'Connor CI, Nielsen BD, Schott HC, Clayton HM.Weight training is commonly used by human athletes to increase strength and fitness. This study was performed to examine the effect of weight-carrying and nutritional supplementation on muscle development and growth in young horses. This study examined the effect of weight-carrying and nutritional supplementation on muscle development and growth. Seventeen horses were divided into 3 groups: controls exercised in a free-flow exerciser, a weight group that performed the same exercise, carrying progressively increasing weight up to 45 kg, and a weight-supplement group, that also received a myo-an...
Kearns CF, McKeever KH, John-Alder H, Abe T, Brechue WF.It has long been known that body mass and, more specifically, lean body mass are strongly correlated with maximal oxygen uptake (VO2max) in man and animals. However, there are no data to date describing this phenomenon in the horse. The purpose of this paper is to examine the relationship between body composition and VO2max in the horse. Twenty-three healthy and unfit Standardbred mares performed an incremental exercise test (GXT) to measure VO2max. Rump fat thickness (RTH), a measure of fat covering, was measured using B-mode ultrasound. Plasma volume, total blood volume and red cell volume w...
Trilk JL, Lindner AJ, Greene HM, Alberghina D, Wickler SJ.Blood lactate measurements are used widely in horses to assess athletic performance, but there are few published data on using lactate as a guide for endurance improvement. The velocity at which blood lactate concentration ([LA]) of 4 mmol/l is reached (v4) is widely used to determine fitness. In an earlier study of v4, exercise at low intensities for longer duration was more effective at improving endurance than shorter, higher intensities. However, the prescription was unchanged during the study (6 weeks). We hypothesised that, to produce greater improvement in v4 in the same time frame, it ...
Hoffman RM, Hess TM, Williams CA, Kronfeld DS, Griewe-Crandell KM, Waldron JE, Graham-Thiers PM, Gay LS, Splan RK, Saker KE, Harris PA.To test the hypothesis that endurance performance may be related quantitatively to changes in blood, we measured selected blood variables then determined their reference ranges and associations with speed during an 80 km race. The plan had 46 horses in a 2 x 2 factorial design testing a potassium-free electrolyte mix and a vitamin supplement. Blood samples were collected before the race, at 21, 37, 56 and 80 km, and 20 min after finishing, for assay of haematocrit, plasma pH, pO2, pCO2, [Na+], [K+], [Ca++], [Mg++], [Cl-], lactate, glucose, urea, cortisol, alpha-tocopherol, ascorbate, creatine ...
McCutcheon LJ, Geor RJ, Hinchcliff KW.This study examined changes in skeletal muscle GLUT4 content and glucose transport in isolated muscle membranes (GT) from horses before and 2 min after standardised submaximal exercise tests (SET) prior to and after completion of 6 weeks of training. Seven horses, age 3-9 years, body mass mean +/- s.e. 530 +/- 19 kg, and sedentary for at least 4 months, completed 6 weeks of training on a treadmill. An initial SET (UT) was performed on a 4 degree incline at a speed equivalent to 55% of pretraining VO2max and was repeated post-training at the same absolute workload (ABS). A third SET (REL) was p...
Franklin SH, Naylor JR, Lane JG.Dorsal displacement of the soft palate (DDSP) is one of the most common obstructive conditions of the upper respiratory tract in the racehorse. The present study was conducted to determine the effects of intermittent dorsal displacement of the soft palate (DDSP) on ventilation and respiratory airflow during high intensity exercise. Videoendoscopic recordings were made of the nasopharynx and larynx simultaneously with measurements of airflow and respiratory gas exchange, during high-speed treadmill exercise in 9 horses with confirmed intermittent DDSP admitted for clinical investigation of poor...
Menzies-Gow NJ, Patterson-Kane JC, McGowan CM.The clinical signs of chronic nodular panniculitis in a three-year-old mare were consistent with a diagnosis of sterile nodular panniculitis, but the mare had histopathological signs of both generalised steatitis and sterile nodular panniculitis. The mare was deficient in vitamin E and selenium.
Hoyt DF, Molinari M, Wickler SJ, Cogger EA.The objective was to understand how the stance-phase kinematics of the hindlimb of trotting horses change with speed under 3 conditions (level, loaded and incline), to compare our results with the predictions of the spring-mass model and to help focus our future studies of muscle function. Video recordings were made of 5 Arabian horses trotting on a treadmill. Five consecutive strides were digitised and averaged for each trial. The angle-time diagrams were qualitatively similar to those reported previously. As speed increases, the range of motion of the hindlimb increases, as predicted by the ...
Betros CL, McKeever KH, Kearns CF, Malinowski K.The purpose of this study was to test the hypotheses that ageing would result in a decline in maximal heart rate (HRmax) and maximal aerobic capacity (VO2max) and, secondarily, that those effects would be reversible with training. Eighteen, healthy, unfit Standardbred mares representing 3 age groups: young (Y = mean +/- s.e. 6.8 +/- 0.4 years, n = 6); middle-aged (MA = 15.2 +/- 0.4 years, n = 6); and old (O = 27.0 +/- 0.2 years, n = 6) were used. HRmax, VO2max and oxygen pulse at VO2max (OPmax) and the velocities producing HRmax (VHRmax) and VO2max (VVO2max) were measured during pretraining an...
Clayton HM, Hoyt DF, Wickler SJ, Cogger EA, Lanovaz JL.Net joint powers and energies have been described in walking horses during the swing phase of the stride in the fore- and hindlimb (Clayton et al. 2001). During trotting, swing phase net joint powers have been described in the forelimb but not in the hindlimb. The effects of velocity on power profiles and energy patterns are important in relation to locomotor energetics. The objective of this study was to evaluate velocity-dependent changes in hindlimb net energy profiles of the swing phase during trotting. Inverse dynamic analysis was used to calculate net joint energies at the hindlimb joint...
Nielsen BD, O'Connor CI, Rosenstein DS, Schott HC, Clayton HM.The use of weight-training to alter bone strength has not been investigated in horses. Recognising that bone responds to loading, we studied the effect of carrying weight on bone development during training. Seventeen horses were divided into 3 groups: controls exercised counterclockwise in a free-flow exerciser; the weight group performed the same exercise carrying progressively increasing weight up to 45 kg and the weight supplement group also received a myo-anabolic supplement. Radiographic equivalence measure of bone mineral content of zones of the third metacarpi (MCIII) was determined on...
Poole DC, Petrisko RN, Anderson L, Fedde MR, Erickson HH.During exercise, the horse can achieve oxygen uptakes and ventilations in excess of 200 ml/kg/min and 1800 l/min, respectively. Whether the diaphragm has the capacity to contribute substantially to inspiratory effort in the exercising horse is not known. To investigate the potential for the horse diaphragm to generate tension, lung displacement and sustain ventilatory function, we measured diaphragm thickness, muscle length and oxidative enzyme activity (citrate synthase) within the ventral, medial and dorsal costal and crural diaphragm. In the diaphragms of 6 mature horses (5 Thoroughbreds, o...
St Lawrence AC, Lawrence LM, Coleman RJ.Many studies have examined the effect of pre-exercise feeding on glucose and insulin responses of horses. The objective of this study was to determine whether exercise performed one hour prior to a meal would attenuate the glucose and insulin responses to a meal. Data collected from 8 mature geldings in a 2 period crossover design experiment were used to determine the postprandial glucose and insulin responses to a meal of oats offered 1 h postexercise. During each period, 4 horses received a test meal following a 14 h fast (NoEx) or a 14 h fast and exercise bout (PostEx) that consisted of 48 ...
Wickler SJ, Hoyt DF, Cogger EA, McGuire R.We hypothesised that trotters during an extended trot have lower energetic costs of locomotion (CT) than horses not bred for this behaviour. VO2 was measured as a function of speed in 7 Arabian horses (3 trained to extend their trotting speeds) and in 2 horses, of similar mass, bred to trot (Hackney). Both oxygen consumption and CT increased with speed and there was, contrary to our hypothesis, no difference between breeds. In Arabians at 6.5 m/s, CT had increased 25% above the CT at 5.0 m/s (normal transition speed). For Hackneys at 6.8 m/s, the CT was almost 35% higher. Stride frequencies in...
Zeyner A, Kirbach H, Fürll M.Feeding a high-fat diet may have potential advantages by maintaining pH homeostasis during intense exercise; conversely, effects including elevated PCV and increased plasma concentration of total protein may indicate effects detrimental to performance by reducing perfusion of tissues and organs. Six horses were used to determine the effects of an replacement of starch (diet '0.00') with 0.33, 0.67, 1.00 and 1.33 g soybean oil/kg bwt/day (diets '033', '0.67', '1.00' and '1.33') on venous and renal acid-base status and fractional clearance (FC) of electrolytes in a postprandial state but prior t...
Takahashi T, Kai M, Hada T, Eto D, Muka K, Ishida N.It has been reported that a small decrease in the strain in the superficial digital flexor tendon (SDFT) occurs if the toe is raised during walking. Although walking on a slope appears similar to raising the toe, it is unclear whether uphill exercise decreases the strain in the SDFT. Because the force or strain on tendons is one of the important factors leading to tendon stress injury, we hypothesised that reducing the force in the SDFT during exercise may prevent tendinitis. The purpose of this study was to determine the effects of treadmill inclination on the force in the SDFT in the walking...
Väihkönen LK, Ojala M, Pösö AR.In red blood cell membranes, the activity of the main lactate carrier, H+-monocarboxylate co-transporter (MCT), varies interindividually and its distribution is bimodal. To show the repeatability of MCT activity, 2 to 5 blood samples were taken, at an interval of approximately 1 year, from 51 Standardbred horses, age 2 weeks-8 years, for a total of 128 observations. The horses could be divided into low (LT) and high (HT) lactate transport activity groups. Age significantly affected (P<0.05) MCT activity such that activity was highest in foals, reached a nadir at 2-3 years, and tended to inc...
Roepstorff L, Johnston C, Drevemo S, Gustås P.According to riding texts, draw reins are supposed to support increased collection. This has not been measured objectively. Therefore, the objective of this study was to determine whether a horse ridden with draw reins would relatively increase weightbearing of the hindquarters while worked with the draw reins compared to a normal rein. Ground reaction forces were measured in 8 horses at the slow trot over a force plate in 3 different experimental set-ups: 1) riding with only a draw rein (DR); 2) riding with the combination of a normal and a draw rein (NR-DR) and 3) riding with a normal rein (...
Art T, Tack S, Kirschvinck N, Busoni V, Votion D, Freeman K, Lekeux P.This study aimed at measuring the functional consequences and the pulmonary cytology changes following a simulation of pulmonary haemorrhage. Pulmonary function tests including lobeline-induced hyperventilation, cytology of tracheo-bronchial wash (TBW) and thoracic radiographs were performed before, as well as 1, 7, 14 and 28 days after, the instillation of 300 ml of blood into the lungs of 4 horses deemed free of exercise-induced pulmonary haemorrhage (Group 1). Control data (Group 2) were obtained by instilling the same volume of saline into the lungs of the same horses in a crossover design...
Silverman SC, Birks EK.This study examined the accuracy and precision of a hand-held, chemical analyser, i-STAT, in measuring selected blood constituents which may be of use in the diagnosis and management of metabolic disorders found in exercising horses. Venous blood samples were taken from 3 Thoroughbred geldings, fit and trained to exercise on a treadmill, both before and after exercise at a speed sufficient to elicit VO2max. The samples were analysed both with the i-STAT and with in-house analysers to compare the values of pH, partial pressure of oxygen (PO2), partial pressure of carbon dioxide (PCO2), bicarbon...
Schott HC, Bohart GV, Eberhart SW.Efflux of potassium (K+) and lactate (lac-) from active skeletal muscle during high intensity exercise leads to increased plasma [K+] and [lac-] in venous and arterial blood. The exercise-induced increases in these ions in human athletes is ameliorated, in part, by uptake by noncontracting tissue, reflected by an increase in the arteriovenous difference across these tissues from rest to exercise. To test the hypothesis that these ions are taken up by noncontracting tissue in strenuously exercising horses, plasma [K+] and [lac-] were measured in blood samples collected simultaneously from the c...
Mantovani R, Rora A, Falomo ME, Bailoni L, Vincenti L.The aims of this study were to compare glycerol (G) at customary concentrations and ethylene glycol (EG) as cryoprotectants for stallion semen in a skimmed milk (SM) extender, to test different EG concentrations and to compare the results of manual and computerized analysis with the hypoosmotic swelling (HOS) test. Ejaculates from two stallions were collected over 3 weeks (6 ejaculates per stallion), diluted in a SM based extender, divided into 4 fractions, centrifuged and diluted again to a concentration of 100 x 10(6) mL(-1) progressive motile spermatozoa (PMS) in addition with the cryoprote...
Koho NM, Väihkönen LK, Pösö AR.The lactate transport activity of red blood cells (RBC) varies widely among different species; in equine RBC, the activity of the main lactate carrier, H+-monocarboxylate co-transporter (MCT), is distributed bimodally. The influence of lactate transport activity is measurable in vivo; after maximal exercise, the RBC lactate concentration in horses with high (HT) lactate transport activity is higher than in those with low (LT) activity. To study the expression of MCT in HT and LT horses, blood samples were taken from 10 horses at rest and after submaximal exercise. Blood and plasma lactate conc...
Pagan JD, Geor RJ, Harris PA, Hoekstra K, Gardner S, Hudson C, Prince A.This study was designed to determine the effects of fat adaptation on carbohydrate and fat oxidation in conditioned horses during low-intensity exercise. Five mature Arabians were studied. The study was conducted as a crossover design with 2 dietary periods, each of 10 week's duration: a) a control (CON) diet, and b) a fat-supplemented (FAT) diet. The total amount of digestible energy (DE) supplied by the fat in the CON and FAT diets was 7% and 29%, respectively. During each period, the horses completed exercise tests at the beginning of the period (Week 0) and after 5 and 10 weeks on the diet...
Barrey E, Desliens F, Poirel D, Biau S, Lemaire S, Rivero JL, Langlois B.Dressage is one of the Olympic equestrian sports practiced in several countries using different horse breeds. Specific characteristics of the walk, trot and canter are required for dressage. It has been assumed that some of these traits could be selected for genetically and contribute to dressage performance. The purpose of this study was to compare the walk, trot and conformation characteristics in young horses of different breeds used for dressage. A total of 142 horses age 3 years were classified into 3 groups of breeds (German, French and Spanish saddle horses) and tested using the same pr...
Essén-Gustavsson B, Jensen-Waern M.Glycogenolysis and lipolysis are essential for energy production in muscle during prolonged exercise but less is known about the role of amino acid metabolism. The aim was to study the effect of an endurance race on pro- and macroglycogen, triglycerides and amino acid concentrations in muscle and on selected blood parameters, especially the amino acid response in the blood during the recovery phase. Seven endurance-trained horses completed a race covering 100-120 km. Blood samples were collected one day before the race, after the finish and 1 and 8 days after the race. Needle biopsy specimens ...
Fintl C, McGorum BC.Brotizolam, acetylcysteine and aloe vera gel were evaluated as ancillary treatments for 29 cases of equine grass sickness. None of the treatments had any significant beneficial effect on the survival of the horses. However, 11 of 13 horses with mild chronic grass sickness survived solely with intensive nursing care.
Lanovaz JL, Khumsap S, Clayton HM, Stick JA, Brown J.The tarsal joint is a common site of injury for many sport horses. Understanding the biomechanics of this complex joint begins with developing a clear picture of the kinematics during normal locomotion. This study describes the 3D kinematics of the tarsal joint by measuring the motion of the tibia and third metatarsus in 4 sound Quarter Horses with targets attached directly to the bones via steel pins. The objective was to determine if the tarsus had significant motion outside the tarsocrural joint. Two Steinmann pins were inserted into the lateral side of the right hindlimb and marker triads ...
Evans DL, Priddle TL, Davie AJ.Relationships between racing performance and plasma lactate and uric acid concentrations after racing were investigated in pacing Standardbred racehorses. The study was undertaken in order to better understand factors that limit racing performance. Twenty horses were tested after races of 1760 m and 28 horses after races over 2160 m. Blood samples were taken 30-60 min before and 8 and 30 min after a race. There were no significant differences between the race distances for prerace and 8 min postrace plasma lactates. Significant low correlations were obtained for plasma lactate concentration 8 ...
Powell DM, Reedy SE, Sessions DR, Fitzgerald BP.Twelve untrained aged mares were used to determine whether 7 days of light exercise improved peripheral tissue insulin sensitivity. Mares were divided into obese-exercised (n = 3), obese-sedentary (n = 3), lean-exercised (n = 3) and lean-sedentary (n = 3) groups. The exercised groups were worked at a trot to a heart rate (HR) of not more than 140 beats/min for 30 min in a round pen. Each group was subjected to 3 euglycaemic hyperinsulinaemic clamps: prior to exercise (P), 24 h following the seventh exercise training session (E) and 9 days postexercise training (PE). Prior to exercise training,...
The Journal of physiologyFebruary 9, 2006
Volume 572, Issue Pt 1 155-164 doi: 10.1113/jphysiol.2006.105635
O'Connor SJ, Ousey JC, Gardner DS, Fowden AL, Giussani DA.This study investigated, in vivo, the mechanisms underlying the development of cardiovascular function in the horse fetus, with particular relevance to baroreflex function and hind limb vascular arterial reactivity to constrictor agonists. Under general anaesthesia, vascular catheters were inserted and a Transonic flow probe was implanted around one of the metatarsal arteries of 13 horse fetuses, either at 0.6 of gestation (n= 6) or at 0.9 of gestation (n= 7, term approximately 335 days). At least 5 days after surgery, pressor, vasoconstrictor and cardiac chronotropic responses to exogenous bo...
Tóth F, Schumacher J.Repair of hernias of the abdominal wall of horses is often augmented by inserting a prosthetic mesh. In this review, we describe the various characteristics of prosthetic meshes used for hernia repair and present 2 systems that are used by surgeons in the human medical field to classify techniques of prosthetic mesh herniorrhaphy. Both of these classification systems distinguish between onlay, inlay, sublay, and underlay placements of mesh, based on the location within the abdominal wall in which the prosthetic mesh is inserted. We separate the published techniques of prosthetic mesh herniorrh...
Dodds L, Knight L, Allen K, Murrell J.To investigate the effect of postsurgical pain on the performance of horses in a novel object and auditory startle task. Methods: Prospective clinical study. Methods: Twenty horses undergoing different types of surgery and 16 control horses that did not undergo surgery. Methods: The interaction of 36 horses with novel objects and a response to an auditory stimulus were measured at two time points; the day before surgery (T1) and the day after surgery (T2) for surgical horses (G1), and at a similar time interval for control horses (G2). Pain and sedation were measured using simple descriptive s...
Gandini M, Giusto G.Accurate reporting of postoperative complications is paramount to understanding procedural outcomes, comparing procedures and assuring quality improvement. Standardising definitions of complications in equine surgeries will improve the evidence of their outcomes. To this end, we proposed a classification for postoperative complications and applied it to a cohort of 190 horses undergoing emergency laparotomy. Methods: A classification system for postoperative complications in equine surgery was developed. Medical records of horses that underwent equine emergency laparotomy and recovered from an...
Blanchard A, Barr EM, Gilger BC.The purpose of this case series is to evaluate the use of spectral domain optical coherence tomography (SD-OCT) imaging in equine corneal disease to demonstrate the feasibility, diagnostic effectiveness, and limitations of this imaging modality. Methods: Retrospective study: Handheld SD-OCT (Envisu, Bioptigen Inc, Morrisville, NC) was used for high-resolution imaging of horses with corneal disease presenting to the North Carolina State University Equine Ophthalmology Service from 2013 to 2018. Results: Fourteen horses were included in this study, including six horses with corneal ulceration, t...
Firth EC, Greydanus Y.The talus and proximal and distal epiphysis of the humerus, radius, femur, tibia and distal metacarpus of 20 foals aged 0 to 150 days were obtained at necropsy and sawn sagittally into slabs 4 to 8 mm thick. The thickness of the cartilage (articular cartilage and unossified epiphyseal cartilage) was measured in three to five places in each slab, using a sliding calliper. In most epiphyses, the site, or sites, of thickest cartilage was constant in all foals examined. The difference between thickest and thinnest cartilage within one epiphysis was greatest in distal femora and least in distal met...
Baird AN, Cohen ND, Taylor TS, Watkins JP, Schumacher J.During a 5-year period, renosplenic entrapment of the large colon was diagnosed in 57 horses referred to the Texas Veterinary Medical Center. The signalment of and clinical signs of disease in these horses were compared with such variables in 200 horses referred for other types of colic. Findings did not support a male gender predilection for this disease, as was previously reported. The case survival rate was 93% for this group of horses. Fourteen of the horses were treated nonsurgically by rolling them clockwise while they were under general anesthesia. Data supported the safety and efficacy...
Machado M, Wilson TM, Ribeiro de Sousa DE, Lopes Câmara AC, Furlan FH, Silva Almeida E Macêdo JT, Pupin RC, Amaral de Lemos RA, Armién AG....Snake bite envenomations in farm animals are generally overestimated as the cause of mortality in rural areas in Latin America. However, most cases are based only on anecdotal information and assumptions, and lack diagnostic evidence. There are few proven reports of envenomation and death in horses caused by snakebites from members of the Bothrops genus (lancehead pit vipers). This study presents epidemiological and clinical-pathological findings of fatal bothropic envenomation in horses from Central Western Brazil in order to contribute to the correct diagnosis of this condition. A survey of ...
Bowling AT, Byrns G, Spier S.The pedigree origin of a base pair substitution in the horse muscle sodium channel gene that confers susceptibility to the muscle disease hyperkalemic periodic paralysis (HYPP) was investigated with a set of 978 Quarter Horses. The horses were chosen at random, based on a collection of blood samples taken between 1989 and 1991 to meet parentage testing requirements, primarily but not exclusively from breeding stallions. The frequency of Quarter Horses positive for the base pair substitution, all heterozygotes, was 4.4%, which corresponds to an allelic frequency of 0.02. All horses positive for...
Leise BS, Fugler LA, Stokes AM, Eades SC, Moore RM.To determine the magnitude and duration of effects of acepromazine administered intramuscularly (IM) on digital and systemic hemodynamic variables in clinically healthy horses. Methods: Experimental study. Methods: Healthy adult horses (n=12). Methods- An ultrasonic Doppler flow probe was surgically implanted around the medial palmar digital artery before the study. Catheters were inserted in the transverse facial artery, lateral palmar digital artery, and jugular vein. A treatment group (n=6) was administered 0.04 mg/kg body weight of acepromazine IM; control horses (n=6) were administered an...
Bowling AT, Gordon L, Penedo MC, Wictum E, Beebout J.We describe a method for agarose IEF under acid conditions in which a single gel can be used to diagnose from equine red cell lysates genetic variants for carbonic anhydrase (CA) and catalase (Cat). Family and population data for 4801 horses of 27 breeds and seven trap sites of Great Basin feral horses are presented to support the presence of a sixth CA allele, CAE, which has been recognized previously, but not described by published data. Allelic frequencies for the two systems suggest it may be appropriate to use this gel for parentage verification programmes or to obtain population data for...
Basher AW, Severin GA, Chavkin MJ, Frank AA.Three horses were examined because of exophthalmos and others signs indicative of a space-occupying orbital mass. In 2 horses, exenteration was used to remove the orbital mass. In a third horse, an orbital tumor and lung metastases were found at necropsy. Routine histologic and Grimelius' histochemical staining were used on fixed tissues; immunohistochemical staining for chromogranin and electron microscopy also were performed. Masses were orbital neuroendocrine tumors. Horses that underwent exenteration were alive 19 and 24 months after surgery. Hypotension was encountered at surgery in both ...
Mayhew IG, Ferguson HO.A group of 834 Thoroughbred horses was surveyed on four central Florida farms for clinical and epidemiologic features of anhidrosis. In addition, comparative analysis was made of serum thyroxine, serum electrolytes, and fractional urinary electrolyte excretion ratios. An overall disease prevalence of 6.12% was observed. Training horses and nonpregnant broodmares had a predilection for the disease. Adolescent horses were infrequently affected. There was no correlation with sex or color. Comparative clinical signs, related to thermoregulatory compromise, included tachypnea and hyperthermia. Long...
Leadon DP, Jeffery R, O'Toole D, Duggan V.This report compiles the available information on unwanted horses in Ireland for 2011 and 2012 and builds upon the previous report for the period 2005 to 2010. Similar trends are present in the high value responsible ownership category and the practicing veterinary profession although extensively involved in horse welfare, euthanises a small proportion of Ireland's unwanted horses. Welfare groups have limited resources and a limited ability to deal with such an extensive problem, which has involved very large numbers of horses. Local authorities continue to have to devote significant efforts a...
Tarr MJ, Olsen RG, Krakowka GS, Cockerell GL, Gabel AA.Erythrocyte rosette (ER) formation of equine peripheral blood lymphocytes (PBL) was characterized. Guinea pig and, to a lesser extent, human erythrocytes formed ER; cat, cow, dog, hamster, mouse, rat, and sheep erythrocytes showed negligible rosetting properties. Conditions of the assay were varied to determine which procedure allowed the largest percentage of rosette formation. The PBL from 20 normal horses were then assayed, averaging 38 +/- 2% ER. To characterize the erythrocyte receptor as being on T or B cells, equine thymocytes from 6 foals were assayed; the thymocytes formed an average ...
Tyrnenopoulou P, Fthenakis GC.Antibiotic administration is a standard therapeutic practice for the treatment of reproductive disorders of equids. This might lead to undesirable microbial imbalance and could favour the acquisition of antibiotic resistance. Therefore, it is imperative for clinicians to understand patterns of antibiotic resistance when considering and developing treatment regimes. Continued engagement of clinicians with novel alternative approaches to treat reproductive infections would be essential in order to address this rising threat within the One Health perspective. The objectives of the present review ...
Suagee-Bedore JK, Linden DR, Bennett-Wimbush K, Splan RK.When fed to horses, high-starch diets elevate plasma concentrations of interleukin-1β (IL-1β) as soon as 1 hour posteating. This increase in IL-β is possibly because of changes in intestinal pH that result from rapid bacterial fermentation of starches and sugars in the digestive tract. The purpose of this research was to investigate the effect of feeding 0.9 kg of grass hay 30 minutes before feeding a concentrate meal on the postprandial rise in IL-1β, compared with control horses receiving the same concentrate without hay first. Six mature geldings were used in a switchback design. Hor...
Leendertse IP.A three year old warm-blood gelding with severe colic was referred to a veterinary clinic. The history revealed that the horse was found early in the morning with severe colic, and laying in the pasture. On arrival the clinical examination showed a complete wet horse with a pulse rate of 92/min, a respiratory rate of 24/min., a pcv of 0.50 L.L.-1, a T. of 38.0 degrees C, and no gastric reflux. Rectal examination revealed a sticky rectal mucous membrane and a colonic impaction together with displacement of the large colon. A diagnostic laparotomy showed an impaction as is seen in horses with Gr...
Tatarniuk DM, Hill JA, Modesto RB, Swor TM, Caston SS, Kersh KD.To report the outcome of horses used in western performance disciplines after deep branch lateral plantar neurectomy/fasciotomy surgery for hind limb proximal suspensory desmopathy (PSD). Methods: Retrospective analysis. Methods: Twenty-one client-owned horses. Methods: Medical records were reviewed (2009-2019) for horses involved in western performance disciplines that had been treated with deep branch lateral plantar neurectomy and plantar fasciotomy for lameness due to hind limb PSD. Follow-up was obtained by reexamination and/or verbal interviews with owners >2 years postoperatively. Res...
Rutllant J, Meyers SA.It is generally accepted that spermatozoa become functionally mature during epididymal transit. The objective of this study was to determine whether the cellular location of equine PH-20 is modified during epididymal transit and, if so, the mechanism for such modification. Sperm were isolated from caput and cauda epididymal regions from stallions undergoing castration (n = 7) and used as whole sperm cell or subjected to nitrogen cavitation for isolation of plasma membrane proteins. Both caput and cauda sperm and sperm protein extracts were subjected to N-deglycosylation, O-deglycosylation, or ...
Green SL, Conlon PD.The pharmacokinetics of amikacin, administered iv at 7 mg/kg, every 8 h, were evaluated over the first 48 h of hospitalisation in 7 critically ill hypoxic premature foals and compared with those in 8 full-term nonhypoxic critically ill neonatal foals. The pharmacokinetic data were used to calculate dosage schedules that would maintain the plasma amikacin concentrations in individual foals within a target range of > or = 15 micrograms/ml but < 30 micrograms/ml for peak values and < or = 3 micrograms/ml for trough values. The results indicated a statistically significant increase in the amikacin...
Harkins JD, Queiroz-Neto A, Mundy GD, West D, Tobin T.This report describes the development of a behaviour chamber and the validation of the chamber of measure locomotor activity of a horse. Locomotor activity was detected by four Mini-beam sensors and recorded on a data logger every 5 min for 22 h. Horses were more active during daytime than in the evening, which was at least partially related to human activity in their surroundings. To validate the ability of the chambers to detect changes in activity, fentanyl citrate and xylazine HCl, agents well-characterized as a stimulant and a depressant, respectively, were administered to five horses. Fe...
Meyer EE, Morris PG, Elcock LH, Weil J.Rabies was diagnosed in 2 adult Quarter Horses with hindlimb hyperesthesia and progressive weakness. Microscopic examination of the cord and brain of the first horse revealed nonsuppurative meningomyelitis and ganglioneuritis in the cord extending cranially to the 6th cervical segment. Fluorescent antibody test results of both horses were positive for rabies in hindlimb peripheral nerve specimens, but negative in sections of the upper lip. Salivary gland, cerebrum, cerebellum, hippocampus, musculocutaneous nerve, cornea, and optic nerve specimens were tested for rabies by fluorescent antibody ...