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Topic:Infection
Infections in horses encompass a range of diseases caused by various pathogens, including bacteria, viruses, fungi, and parasites. These infections can affect different systems within the horse, such as the respiratory, gastrointestinal, and integumentary systems, leading to a variety of clinical signs depending on the pathogen and the severity of the infection. Common infectious diseases in horses include equine influenza, strangles, and equine herpesvirus. Diagnosis often involves clinical examination, laboratory testing, and sometimes imaging, to identify the causative agent and assess the extent of the disease. Treatment strategies may include antimicrobial therapy, supportive care, and preventive measures such as vaccination and biosecurity practices. This page aggregates peer-reviewed research studies and scholarly articles that explore the pathogenesis, diagnosis, treatment, and prevention of infectious diseases in equine populations.
Studies with equine infectious anemia virus: transmission attempts by mosquitoes and survival of virus on vector mouthparts and hypodermic needles, and in mosquito tissue culture. Biological and mechanical transmission trials with Psorophora columbiae (Dyar and Knab) and Aedes sollicitans (Walker) and ponies acutely infected with equine infectious anemia virus (EIAV) were negative. The EIAV antigen was detected by radioimmunoassay in Ae sollicitans immediately after the mosquitoes had fed on an acutely ill pony, but not 14 days after feeding. Psorophora columbiae mosquitoes had detectable EIAV antigen as determined by radioimmunoassay 24 hours after they fed on an acutely ill pony; this antigen was not detected again until 6 days after feeding and was still detected 14 ...
[Prevalence of lungworm D. arnfieldi (Cobbold 1884) in donkeys in Denmark and in horses in herds together with donkeys (author’s transl)]. During a 5 months' period from January to May 1981 faecal samples of 176 donkeys from 59 herds all over the country were examined at the Institute of internal medicine, The Royal Veterinary and Agricultural University, Copenhagen. In addition, the investigation also included 106 horses from 30 of the donkey herds and 34 horses hospitalized with symptoms of dyspnoea and chronic coughing. In all, 87.5% of the donkeys were shown to excrete D. arnfieldi larvae, often in very high numbers, and the larval excretion was the only symptom of lungworm infection. There was no significant correlation betw...
A wire reclamation incinerator as a source of environmental contamination with tetrachlorodibenzo-p-dioxins and tetrachlorodibenzofurans. The authors investigated an outbreaks of unusual illnesses in humans and horses residing within 1.3 km of a wire reclamation incinerator. The study included site visits; medical and veterinary examinations; analyses of furnace ash, fly ash, soil, and biologic samples for air residues. Tetrachlorodibenzo-p-dioxins (TCDDs) and tetrachlorodibenzofurans (TCDFs) were discovered in furnace ash, fly ash, soil, horse fat, and horse liver samples.
Actinobacillus lignieresii infection after a horse bite. Perforation is the most serious complication of fibreoptic endoscopy.1
The commonest site of perforation during upper gastrointestinal
endoscopy is the oesophagus,' but predisposing factors have not been
fully documented. We report a retrospective survey of major endoscopy
units in the United Kingdom and attempt to identify the factors associated with oesophageal perforation.
Surgical management of uterine torsion in the mare: a review of 26 cases. Uterine torsion was diagnosed in 26 mares of various breeds. The mean duration of gestation was 9.6 months. The most common clinical history was intermittent unresponsive colic of varying duration. Diagnosis of uterine torsion was confirmed by rectal palpation, and surgical correction was achieved in most cases by standing flank laparotomy and manual repositioning of the gravid uterus. Recumbent laparotomy was used only if the mare was intractable, the uterus was ruptured, or hysterotomy was indicated. Of 20 foals determined to be alive during surgery, 14 (70%) were subsequently born alive.
The relationship of two equine mycoplasmas to Mycoplasma mycoides. Two unidentified mycoplasmas, N3 and N11, isolated from the respiratory tract of horses, were found to cross-react with strains of M. mycoides subsp. mycoides in indirect immunofluorescence tests, growth-inhibition tests carried out by the running drop/agar-well method, and in complement-fixation and double immunodiffusion tests. Serologically, the equine mycoplasmas were not completely identical with any of the reference strains of M. mycoides with which they were compared. Their cultural characteristics, ability to digest coagulated serum and casein, and survival at 45 degrees C, however, su...
Treatment of equine phycomycosis by immunotherapy and surgery. Treatment of equine phycomycosis with a vaccine derived from ultrasonicated hyphae of Hyphomyces destruens was attempted in 30 cases of clinical hyphomycosis, 10 cases of hyphomycosis following unsuccessful surgery and 5 cases of basidiobolomycosis. Approximately 53% of animals with clinical hyphomycosis were cured after vaccination, while a further 33% clinically improved. All horses with hyphomycosis treated within 2 weeks of unsuccessful surgery were cured. There was no response to vaccination with a Hyphomyces preparation in horses with basidiobolomyucosis, while surgery alone resulted in ...
Congenital duodenal stenotic diaphragm in the foal. A two-month-old female foal with duodenal stenosis is described. The foal was in poor condition and showed an abnormal stable behaviour. She stood preferably with her head stretched out and reposing on the mare's back or on the stable ridge. Salivation was an important symptom. Clinical and radiological examination of the oral cavity, the pharynx, and the oesophagus showed no abnormalities, except for the antiperistaltic wave along the oesophagus. Because of her bad condition the filly was euthanized. At post mortem examination, apart from leukoplakia, an erosive ulcerative inflammation was fo...
Clinical and structural features of equine enteroliths. Enteroliths were obtained by laparotomy or necropsy of 11 horses, and a collection of smaller concretions was found on pasture. Following analysis by energy-dispersion x-ray analysis and x-ray diffraction, they were found to consist primarily of ammonium magnesium phosphate. Several minor elements were detected, including titanium in some concretions. From a farm with a history of enterolith obstructions, the well water contained a high proportion of magnesium in relation to the other cations.
Experimental induction of Proteus mirabilis cystitis in the pony and evaluation of therapy with trimethoprim-sulfadiazine. Proteus mirabilis cystitis was induced in 9 ponies by chemically eroding the bladder mucosa before the organism was inoculated. Comparisons were made in the treatment of P mirabilis cystitis between ponies treated daily for 13 days with a trimethoprim-sulfadiazine (TMP-SDZ) paste and both positive and negative controls. Urine cultures from ponies treated with TMP-SDZ became negative for P mirabilis between days 3 and 9 after the start of the treatment, whereas positive controls remained infected until day 13. Urine cultures from all ponies were negative for P mirabilis on day 28. Urine concent...
Pathologic features of horses given avirulent equine arteritis virus intramuscularly. Twenty horses that were seronegative for equine arteritis virus antibodies were inoculated IM with live equine arteritis virus vaccine. The inoculation did not cause clinical signs of disease. A mild, transient febrile reaction developed in 6 horses, 3 of which were in poor condition before inoculation. Six horses, 2 of which were in poor condition before inoculation, experienced mild lymphopenia. Necropsy revealed mild lesions in the lymph nodes of 6 horses (3 of which were in poor condition before inoculation). Maximum concentrations of virus were detected in the lymph nodes and were consist...
Anthelmintic control of lungworm in donkeys. A field study was designed to investigate the re-establishment of patent lungworm infections in donkeys following an anthelmintic treatment regime which was effective against Dictyocaulus arnfieldi. In April 1979 faecal samples from 259 donkeys were examined and each animal classified as a negative, low positive or high positive excretor of lungworm larvae. During the summer the control group of 126 donkeys showed an increase in the number of excretors from 80 per cent in April to 91 per cent in October. At the same time there was a rise in the faecal larval output of individual animals so tha...
Equine salmonellosis: a contemporary view. The practical implications of equine salmonellosis in the light of present knowledge are reviewed. Emphasis is placed on the various clinical forms which the disease may take. These include asymptomatic infections, signs of fever, anorexia and depression, severe acute diarrhoea and the septicaemic form. Diagnosis depends on recovery of the organism from the blood or faeces or, at necropsy, from tissues. In asymptomatic infections, it may be necessary to make serial faecal cultures over several days before a negative diagnosis may be made with any degree of certainty. Isolation of salmonellae i...
Intestinal threshold of an enzootic strain of Venezuelan encephalitis virus in Culex (Melanoconion) taeniopus mosquitoes and its implications to vector competency and vertebrate amplifying hosts. The minimal intestinal dose of an enzootic strain of Venezuelan encephalitis (VE) virus for Culex (Melanoconion) taeniopus mosquitoes caught at a marsh habitat of VE virus in Guatemala was less than five plaque forming units (pfu) of virus. Ingestion of this dose of virus in blood of viremic hamsters resulted in transmission of virus to other hamsters. This low intestinal threshold of an enzootic strain of VE virus indicates that the natural Guatemalan population of Cu. (Mel.) taeniopus can acquire VE virus from vertebrates that have viremia levels as low as 1,000-5,000 pfu/ml of blood, provid...
Antigenic analyses of tissues and excretory and secretory products from Strongylus vulgaris. Rabbit antisera were prepared against veronal buffered saline extracts of L4 and L5 Strongylus vulgaris, adult S. vulgaris and adult Strongylus equinus retrieved from naturally infected horses. In agar gel diffusion with these antisera, adult S vulgaris and S. equinus each appeared to have at least one unique antigen; larval S. vulgaris appeared to have two species-specific and two stage-specific antigens. There were several common antigens. Excretory and secretory products were collected also from L4 and L5 an maintained over several days in tissue culture fluid. In agar gel diffusion against...
Apparent inactivity of several antiparasitic compounds against the eyeworm Thelazia lacrymalis in equids. Activity of 15 compounds, given alone or in mixtures [butamisole, cambendazole, caviphos, febantel (alone or with trichlorfon), fenbendazole, ivermectin, levamisole-piperazine, oxfendazole, oxibendazole, pyrantel pamoate (alone or with piperazine-carbon disulfide complex), thiabendazole (alone or with piperazine or with trichlorfon), tioxidazole, and trichlorfon], against Thelazia lacrymalis was evaluated in 102 equids. Determination of activity was based on comparison of infection rate in treated animals examined at necropsy with infection rate of dead equids in our contemporary surveys. None...
Controlled tests of ivermectin against migrating Strongylus vulgaris in ponies. Twelve pony foals were reared worm-free and inoculated with Strongylus vulgaris. On day 7 after inoculation, 6 ponies were given ivermectin IM at a dose of 200 micrograms/kg of body weight and on day 28 were necropsied. Ivermectin was effective in eliminating early 4th-stage S vulgaris larvae and reducing clinical signs associated with acute arteritis. After administrative ivermectin was effective against early 4th-stage Strongylus vulgaris larvae in ponies when administered at 100, 300, or 800 micrograms/kg of body weight. The purpose of the present study was to report on a more extensive tri...
A comparative study of the toxicity of Fusarium verticillioides (= F. moniliforme) to horses, primates, pigs, sheep and rats. An isolate of Fusarium verticillioides (MRC826) that induced experimental leukoencephalomalacia, also caused acute toxicity when fed to pigs and administered per rumen fistula to sheep. Pigs developed severe pulmonary oedema while sheep manifested severe nephrosis and hepatosis. A less toxic isolate (F. verticillioides MRC602), fed to baboons, resulted in acute congestive heart failure or hepatic cirrhosis, depending on the dose. Both isolates were toxic to rats and caused similar lesions, namely, hepatic cirrhosis and intraventricular cardiac thrombosis.
Haloxon: critical tests of antiparasitic activity in equids. Critical tests were conducted in 14 naturally infected equids (13 horses and 1 pony) to evaluate the antiparasitic activity of haloxon. Single doses were administered by stomach tube to 3 horses and 1 pony (60 mg/kg of body weight), by addition to the feed of 3 horses (60 mg/kg), and intraorally by powder gun to 7 horses (65 mg/kg). Haloxon was efficacious (99% to 100%) against infections of Parascaris equorum, Oxyuris equi (mature and immature), and Strongylus vulgaris at both dosage levels. Probstmayria vivipara parasites were removed in 1 horse treated at 60 mg/kg by stomach tube and S equi...
Anthelmintic efficacy fenbendazole paste in equines. A single oral dose of fenbendazole (FBZ) paste at 7,5 mg/kg body mass was given to 5 horses. It was highly effective against adults of the following genera: Cyathostomum, Cylicostephanus, Cylicondontophorus, Poteriostomum, Cylicocyclus, Triodontophorus, Oesophagodontus (and other genera belonging to the subfamily Cyathostominae). Similarly, high efficacy was obtained against the adults of the following species: Oxyuris equi, Strongylus vulgaris, Strongylus equinus and Probstmayria vivipara. These results were confirmed in 12 horses and in addition FBZ at 7,5 mg/kg was highly effective against ...
