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Topic:Infectious Disease

Infectious diseases in horses encompass a range of illnesses caused by bacteria, viruses, fungi, or parasites. These diseases can affect various systems within the equine body, leading to symptoms that range from mild discomfort to severe systemic illness. Common infectious diseases in horses include equine influenza, strangles, equine herpesvirus, and West Nile virus. These diseases can be transmitted through direct contact with infected animals, contaminated surfaces, or vectors such as insects. Understanding the mechanisms of transmission, pathogenesis, and immune response is essential for effective prevention and control. This page compiles peer-reviewed research studies and scholarly articles that explore the epidemiology, diagnosis, treatment, and management of infectious diseases in horses.
Venezuelan equine encephalomyelitis virus: concentration, partial purification, inactivation and immunogenicity.
Comparative immunology, microbiology and infectious diseases    January 1, 1983   Volume 6, Issue 1 31-37 doi: 10.1016/0147-9571(83)90034-6
Foster NM, Barber TL, Walton TE.Venezuelan equine encephalomyelitis (VEE) TC-84 vaccinal virus, from 10-1. quantities of infected duck embryo fibroblast cell culture fluids, was isolated by combined continuous-flow centrifugation with isopycnic banding in sucrose. Most of the recovered infectivity and hemagglutinating activity were in a single band at a buoyant density (rho) of 1.2. About 90% of the total input protein (450-520 mg) was removed with the effluent, whereas most of the remaining 10% also banded at a rho of 1.2. Infectivity was inactivated with formalin at a final concentration of 0.05% at 37 degrees C for 24 hr....
Human Venezuelan equine encephalitis virus infection and diabetes in Zulia State, Venezuela.
Journal of medical virology    January 1, 1983   Volume 11, Issue 4 327-332 doi: 10.1002/jmv.1890110408
Ryder E, Ryder S.Venezuelan equine encephalitis (VEE) virus has been implicated as producing alterations in glucose metabolism in animals. We performed oral glucose tolerance tests and measured serum immunoreactive insulin responses in 13 patients who were infected by VEE virus during an epidemic in 1969, in Zulia State, Venezuela. No significant alterations in the glucose tolerance test were found. Sera of 86 diabetic outpatients and 98 control individuals with normal glycemia at a local hospital were tested for antibodies to VEE virus by hemagglutination inhibition. No statistically significant difference wa...
Transmission studies with the contagious equine metritis bacterium in albino Swiss mice.
Comparative immunology, microbiology and infectious diseases    January 1, 1983   Volume 6, Issue 3 227-234 doi: 10.1016/0147-9571(83)90015-2
Timoney PJ, Dillon PB, Geraghty VP, McArdle JF.Aspects of experimental transmission of the causal bacterium of contagious equine metritis (CEM) to albino Swiss mice were investigated. Whereas infection was established in the majority of female mice, the organism was recovered from only a limited number of male mice after challenge. No clinical evidence of infection was observed in the experimental mice. There was only one instance of presumptive venereal transmission of the CEM bacterium. One third of infected females conceived and had normal litters.
The use of fluorescent antibody technique for the diagnosis of equine histoplasmosis “epizootic lymphangitis”.
Mykosen    December 1, 1982   Volume 25, Issue 12 683-686 doi: 10.1111/j.1439-0507.1982.tb01943.x
Abou-Gabal M, Al-Bana A, El-Gendi M.No abstract available
Effect of Mycoplasma orale on growth of equine arteritis virus in Vero cells.
Nihon juigaku zasshi. The Japanese journal of veterinary science    December 1, 1982   Volume 44, Issue 6 989-991 doi: 10.1292/jvms1939.44.989
Tsukamoto K, Konishi S, Ogata M.No abstract available
Immunogenicity of equine herpesvirus type 1 (EHV1) and equine rhinovirus type 1 (ERhV1) following inactivation by betapropiolactone (BPL) and ultraviolet (UV) light.
Veterinary microbiology    December 1, 1982   Volume 7, Issue 6 535-544 doi: 10.1016/0378-1135(82)90047-5
Campbell TM, Studdert MJ, Blackney MH.Some kinetic data on the inactivation of equine herpesvirus type 1 (EHV1) and equine rhinovirus type 1 (ERhV1) by betapropiolactone (BPL) and ultraviolet (UV) irradiation are reported. 0.25% BPL at 37 degrees C for 1 h reduced the titre of EHV1 by greater than 10(3 . 4) and of ERhV1 by greater than 10(4 . 1) TCID50/ml. UV irradiation (334 microW/cm2) produced similar reductions in titre after 2 min. These data were used as a basis for inactivating EHV1 and ERhV1 by the combined action of BPL and UV irradiation. Viruses were exposed to 0.1% BPL for 1 h at 4 degrees C with constant stirring, fol...
Prevalence and distribution of antibodies to Getah and Japanese encephalitis viruses in horses raised in Hokkaido.
Nihon juigaku zasshi. The Japanese journal of veterinary science    December 1, 1982   Volume 44, Issue 6 967-970 doi: 10.1292/jvms1939.44.967
Matsumura T, Goto H, Shimizu K, Sugiura T, Ando Y, Kumanomido T, Hirasawa K, Akiyama Y.No abstract available
Characterization of the major antigens of Haemophilus equigenitalis (contagious equine metritis organism).
The Journal of hygiene    December 1, 1982   Volume 89, Issue 3 529-538 doi: 10.1017/s0022172400071102
Corbel MJ, Brewer RA.Immunoelectrophoresis of ultrasonically disrupted Haemophilus equigenitalis (contagious equine metritis organism) cells against rabbit and equine antisera disclosed at least 11 precipitating antigens. Two of these, a polysaccharide and a lipopolysaccharide-protein complex, were of high molecular weight and located on the cell surface. The remaining antigens were intracellular and were small- to medium-sized proteins. The surface antigens were the most significant in relation to the serological response in infected horses. They also reacted with sera from apparently healthy cattle, but the reas...
Microsporum gypseum in a horse.
The Veterinary record    November 20, 1982   Volume 111, Issue 21 492 doi: 10.1136/vr.111.21.492-a
Philpot CM, Berry AP.No abstract available
A common code of practice for the control of contagious equine metritis and other equine reproductive diseases for the 1983 covering season in France, Ireland and the United Kingdom.
The Veterinary record    November 20, 1982   Volume 111, Issue 21 474-477 doi: 10.1136/vr.111.21.474
No abstract available
Isolation of the contagious equine metritis organism from colts and fillies in the United Kingdom and Ireland.
The Veterinary record    November 20, 1982   Volume 111, Issue 21 478-482 doi: 10.1136/vr.111.21.478
Timoney PJ, Powell DG.Between January 1978 and August 1982 the streptomycin resistant strain of the contagious equine metritis organism (CEMO) was isolated from 15 colts and two fillies in the United Kingdom and Ireland. A first season stallion was also suspected of having initiated an outbreak of contagious equine metritis (CEM) at the beginning of the 1982 breeding season. A detailed investigation of the breeding history of the dams and sires of each positive individual indicated that in a number of cases the CEMO was acquired either in utero or following transmission at the time of parturition. In several other ...
Immunoprophylaxis in the horse.
Journal of the American Veterinary Medical Association    November 15, 1982   Volume 181, Issue 10 1150-1153 
Ardans AA.No abstract available
Microsporum equinum in North America.
Journal of clinical microbiology    November 1, 1982   Volume 16, Issue 5 943-947 doi: 10.1128/jcm.16.5.943-947.1982
Kane J, Padhye AA, Ajello L.Microsporum equinum was isolated in Ontario, Canada, from five human and two equine cases of ringworm infection. This dermatophyte was previously recovered from North American horses on several occasions, but was considered to be M. canis. We regard M. equinum as distinct from M. canis. It can be differentiated from M. canis by the smaller size of its macroconidia, its failure to perforate hair in vitro, its poor growth and sporulation on bromocresol purple casein dextrose agar, and its incompatibility with Nannizzia otae, the telemorph of M. canis.
In vitro blastogenesis of equine lymphocytes by inactivated equine adenovirus type 1 antigen.
American journal of veterinary research    November 1, 1982   Volume 43, Issue 11 1922-1925 
Campbell TM, Studdert MJ.An inactivated equine adenovirus type 1 (EAdV1) vaccine was administered to 4 horses. The horses had virus-neutralizing (VN) antibody titers before they were vaccinated, but developed higher VN antibody titers in response to vaccination. Nonvaccinated control horses did not show increases in VN antibody during the study, indicating that any increase in antibody titer in vaccinated horses was a result of vaccination and not due to an EAdV1 epizootic during the study. Specific EAdV1 in vitro lymphocyte blastogenesis (LB) was evaluated, using lymphocytes from 4 vaccinated and 2 control horses. Ho...
Experimental Brucella abortus infection in the horse: observations during the three months following inoculation.
Research in veterinary science    November 1, 1982   Volume 33, Issue 3 351-359 
MacMillan AP, Baskerville A, Hambleton P, Corbel MJ.Five mares, one stallion and a colt foal were inoculated intraconjunctivally with Brucella abortus strain 544. No clinical signs of disease developed except mild pyrexia. Intermittent bacteraemia was detected in the mares but not in the stallion or foal. Antibodies to B abortus became detectable from the second week after inoculation. Titres in the serum agglutination and complement fixation tests declined substantially after six to eight weeks but reactions to the Coombs antiglobulin, 2-mercaptoethanol and immunodiffusion tests were maintained. No consistent changes in biochemical or haematol...
Serologic evidence of Jamestown Canyon and Keystone virus infection in vertebrates of the DelMarVa Peninsula.
The American journal of tropical medicine and hygiene    November 1, 1982   Volume 31, Issue 6 1245-1251 doi: 10.4269/ajtmh.1982.31.1245
Watts DM, LeDuc JW, Bailey CL, Dalrymple JM, Gargan TP.Serological data accumulated during the past decade indicated that a variety of feral and domestic animals of the Delaware-Maryland-Virginia (DelMarVa) Peninsula were infected with Jamestown Canyon (JC) and/or Keystone (KEY) viruses (Bunyaviridae, California serogroup). Neutralizing (N) antibody to JC virus was most prevalent in white-tailed deer, sika deer, cottontail rabbits and horses. KEY virus N antibody was detected most frequently in gray squirrels and domestic goats. N antibody indicative of past infection by one or both viruses also was found in raccoons, horses and humans. JC and/or ...
Diarrhoea in foals associated with rotavirus.
The Veterinary record    October 30, 1982   Volume 111, Issue 18 421 doi: 10.1136/vr.111.18.421
Strickland KL, Lenihan P, O'Connor MG, Condon JC.No abstract available
CEM (contagious equine metritis) in Northern Ireland.
The Veterinary record    October 23, 1982   Volume 111, Issue 17 400 doi: 10.1136/vr.111.17.400-a
O'Brien JJ.No abstract available
Microsporum gypseum as the cause of ringworm in a horse.
The Veterinary record    October 23, 1982   Volume 111, Issue 17 396 doi: 10.1136/vr.111.17.396
Tanner AC, Quaife RA.No abstract available
CEM (contagious equine metritis) in the Republic of Ireland.
The Veterinary record    October 23, 1982   Volume 111, Issue 17 400-401 doi: 10.1136/vr.111.17.400
Timoney PJ, Strickland KL.No abstract available
Experimental infection on a horse with Microsporum canis from equine ringworm.
Nihon juigaku zasshi. The Japanese journal of veterinary science    October 1, 1982   Volume 44, Issue 5 845-847 doi: 10.1292/jvms1939.44.845
Ichijo S, Takatori K, Tanaka I, Konishi T.No abstract available
[Sarcocystis bertrami Doflein, 1901, a sarcosporidia of the horse. Equus caballus].
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B    October 1, 1982   Volume 29, Issue 9 681-701 
Hinaidy HK, Loupal G.No abstract available
Study of agglutinins to Brucella abortus, B canis and Actinobacillus equuli in horses.
Equine veterinary journal    October 1, 1982   Volume 14, Issue 4 302-304 doi: 10.1111/j.2042-3306.1982.tb02434.x
Nicoletti PL, Mahler JR, Scarratt WK.Horses at a veterinary teaching hospital and a slaughterhouse were surveyed for antibodies to Brucella abortus, B canis and Actinobacillus equuli. Four of the 141 hospitalised horses and none of the 73 slaughtered horses had titres of 1:100 or greater to B abortus. Six horses of both populations reacted to the card test. One was culture positive. A card test using B canis antigen was positive in 38 per cent of the sera from hospitalised horses and all of the slaughtered horses. Twenty (27.4 per cent) of the latter group had high tires in a tube agglutination test. High titres could not be redu...
A sero-epizootiological survey on rotavirus infection in foals.
Nihon juigaku zasshi. The Japanese journal of veterinary science    October 1, 1982   Volume 44, Issue 5 819-821 doi: 10.1292/jvms1939.44.819
Imagawa H, Hirasawa K, Akiyama Y, Omori T.No abstract available
[Piroplasmas of horses–impact on the international horse trade].
Berliner und Munchener tierarztliche Wochenschrift    October 1, 1982   Volume 95, Issue 19 368-374 
Friedhoff KT.No abstract available
Development of Sarcocystis fayeri in the equine.
The Journal of parasitology    October 1, 1982   Volume 68, Issue 5 856-860 
Fayer R, Dubey JP.Eight ponies and a horse were inoculated orally with sporocysts of Sarcocystis fayeri from dogs. They were examined for clinical signs of infection and killed 10, 15, 20, 25, 30, 50 (horse), 77, 101, and 156 days after inoculation (DAI). Elevated temperature was observed in three ponies 20 and 26 DAI and anemia was observed in three ponies and the horse 15 to 69 DAI. Schizonts were found in or near cells lining capillaries or arteries of the heart, brain, and kidney 10, 20, and 25 DAI. Immature cysts containing only metrocytes were first found in muscles 50 DAI. Mature intramuscular cysts cont...
Observations on equine leptospirosis.
Australian veterinary journal    October 1, 1982   Volume 59, Issue 4 124 doi: 10.1111/j.1751-0813.1982.tb02747.x
Kirkman DB, Campbell RS, Miller RI.No abstract available
Types of Pseudomonas aeruginosa isolated from horses.
Equine veterinary journal    October 1, 1982   Volume 14, Issue 4 329-332 doi: 10.1111/j.2042-3306.1982.tb02446.x
Atherton JG, Pitt TL.Pseudomonas aeruginosa isolates from equine clinical material were categorised according to their serotype and phage type. Epidemiological evidence showed that serotypes 02a, 03, 04, 06, 09 and 010 were the cause of genital and non-genital infections; somatic type 03 accounted for 50 per cent of isolates. The laboratory tests used were of no value in predicting whether or not a particular isolate was likely to be a venereal pathogen, but all the serotypes encountered had the potential to be pathogenic, given a favourable environment in which to multiply.
Variation in arbovirus infection rates in species of birds sampled in a serological survey during an encephalitis epidemic in the Murray Valley of South-eastern Australia, February 1974.
The Australian journal of experimental biology and medical science    October 1, 1982   Volume 60 (Pt 5) 471-478 doi: 10.1038/icb.1982.52
Marshall ID, Brown BK, Keith K, Gard GP, Thibos E.There was extensive and exuberant breeding of waterbirds before and during an epidemic of arboviral encephalitis in the Murray Valley of south eastern Australia in 1974. As estimated by haemagglutination inhibition tests on 432 bird sera collected between 4th and 13th February, 1974, infection with Murray Valley encephalitis virus, Kunjin virus and possibly other flaviviruses was concentrated in species of the Order Ciconiiformes (55% positive) and Pelecaniformes (41%), compared with only 5% in Anseriformes. Although Sindbis virus infections were also highest in these 2 Orders (56% and 46%, re...
[EHV-1 myeloencephalitis in the horse].
Berliner und Munchener tierarztliche Wochenschrift    September 1, 1982   Volume 95, Issue 17 321-325 
Kraft W, Grabner A, Fiebiger I.No abstract available