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Topic:Pain Management

Pain management in horses involves various strategies and interventions designed to alleviate discomfort and improve the well-being of equine patients. It encompasses pharmacological approaches, such as the use of non-steroidal anti-inflammatory drugs (NSAIDs), opioids, and other analgesics, as well as non-pharmacological methods like physical therapy, acupuncture, and environmental modifications. Effective pain management aims to address both acute and chronic pain conditions, which can result from injuries, surgeries, or diseases such as laminitis and arthritis. This page aggregates peer-reviewed research studies and scholarly articles that explore the mechanisms, efficacy, and safety of different pain management techniques in horses, contributing to the understanding and advancement of equine veterinary care.
Evaluation of avocado and soybean unsaponifiable extracts for treatment of horses with experimentally induced osteoarthritis.
American journal of veterinary research    June 5, 2007   Volume 68, Issue 6 598-604 doi: 10.2460/ajvr.68.6.598
Kawcak CE, Frisbie DD, McIlwraith CW, Werpy NM, Park RD.To evaluate the use of a combination of avocado and soybean unsaponifiable (ASU) extracts for the treatment of experimentally induced osteoarthritis in horses. Methods: 16 horses. Methods: Osteoarthritis was induced via osteochondral fragmentation in 1 middle carpal joint of each horse; the other joint underwent a sham operation. Horses were randomly allocated to receive oral treatment with ASU extracts (1:2 [avocado-to-soybean] ratio mixed in 6 mL of molasses; n = 8) or molasses (6 mL) alone (placebo treatment; 8) once daily from days 0 to 70. Lameness, response to joint flexion, synovial eff...
The effect of plain, eggbar and 6 degrees-wedge shoes on the distribution of pressure under the hoof of horses at the walk.
New Zealand veterinary journal    May 31, 2007   Volume 55, Issue 3 120-124 doi: 10.1080/00480169.2007.36753
Rogers CW, Back W.To quantify the effect of plain, wedged and eggbar shoes on the distribution of pressure under the hoof of horses at the walk, at selected areas of interest (AOI), to find scientific evidence for the perceived efficacy of these shoes in the treatment of palmar heel pain. Methods: Six clinically sound adult Warmblood mares weighing 551 (SD 25) kg were shod (forelegs) with either plain, eggbar or 6 degrees-wedge shoes using a latin-square experimental design. All horses were shod by the same farrier, and each balanced and aligned for its individual conformation. Data were collected on three walk...
The effect of induced forelimb lameness on thoracolumbar kinematics during treadmill locomotion.
Equine veterinary journal    May 25, 2007   Volume 39, Issue 3 197-201 doi: 10.2746/042516407x173668
Gómez Alvarez CB, Wennerstrand J, Bobbert MF, Lamers L, Johnston C, Back W, van Weeren PR.Lameness has often been suggested to result in altered movement of the back, but there are no detailed studies describing such a relationship in quantitative terms. Objective: To quantify the effect of induced subtle forelimb lameness on thoracolumbar kinematics in the horse. Methods: Kinematics of 6 riding horses was measured at walk and at trot on a treadmill before and after the induction of reversible forelimb lameness grade 2 (AAEP scale 1-5). Ground reaction forces (GRF) for individual limbs were calculated from kinematics. Results: The horses significantly unloaded the painful limb by 1...
Structural and biomechanical aspects of equine sacroiliac joint function and their relationship to clinical disease.
Veterinary journal (London, England : 1997)    May 9, 2007   Volume 176, Issue 3 281-293 doi: 10.1016/j.tvjl.2007.03.005
Goff LM, Jeffcott LB, Jasiewicz J, McGowan CM.Pain originating from the sacroiliac joint (SIJ) in horses has long been associated with poor performance, yet specific diagnosis of sacroiliac dysfunction (SID) has been difficult to achieve. Clinical presentation of SID appears to fall into two categories. The first, presenting as pain and poor performance, is responsive to local analgesia of periarticular structures with poorly defined pathology. The second presents primarily as poor performance with bony pathological changes as a result of chronic instability. Diagnostic tests based on biomechanics as well as manual provocation for SIJ pai...
Effects of vertebral mobilization and manipulation on kinematics of the thoracolumbar region.
American journal of veterinary research    May 3, 2007   Volume 68, Issue 5 508-516 doi: 10.2460/ajvr.68.5.508
Haussler KK, Hill AE, Puttlitz CM, McIlwraith CW.To measure passive spinal movements induced during dorsoventral mobilization and evaluate effects of induced pain and spinal manipulative therapy (SMT) on passive vertebral mobility in standing horses. Methods: 10 healthy adult horses. Methods: Baseline vertical displacements, applied force, stiffness, and frequency of the oscillations were measured during dorsoventral spinal mobilization at 5 thoracolumbar intervertebral sites. As a model for back pain, fixation pins were temporarily implanted into the dorsal spinous processes of adjacent vertebrae at 2 of the intervertebral sites. Vertebral ...
An investigation into the depth of penetration of low level laser therapy through the equine tendon in vivo.
Irish veterinary journal    May 1, 2007   Volume 60, Issue 5 295-299 doi: 10.1186/2046-0481-60-5-295
Ryan T, Smith R.Low level laser therapy (LLLT) is frequently used in the treatment of wounds, soft tissue injury and in pain management. The exact penetration depth of LLLT in human tissue remains unspecified. Similar uncertainty regarding penetration depth arises in treating animals. This study was designed to test the hypothesis that transmission of LLLT in horses is increased by clipping the hair and/or by cleaning the area to be treated with alcohol, but is unaffected by coat colour. A LLLT probe (810 nm, 500 mW) was applied to the medial aspect of the superficial flexor tendon of seventeen equine forelim...
Raising heels of hind hooves changes the equine coffin, fetlock and hock joint angle: a kinematic evaluation on the treadmill at walk and trot.
Equine veterinary journal. Supplement    April 4, 2007   Issue 36 427-430 doi: 10.1111/j.2042-3306.2006.tb05581.x
Peham C, Girtler D, Kicker C, Licka T.Raised heels are commonly recommended for various equine orthopaedic conditions. However, the simultaneous effect of raised heels on the different joint angles of the equine hindlimb throughout the motion cycle has not been previously evaluated. Objective: To document the simultaneous effect of raised heels on the joint angles of the equine hindlimb coffin, fetlock and hock joints. Methods: Eight sound, adult, Warmblood horses were evaluated barefoot and with a heel wedge of 8 or 16 degrees, walking and trotting on a horizontal treadmill. Markers placed on the dorsal and cranial aspect of the ...
[Influence of the riding discipline and riding intensity on the incidence of back pain in competitive horseback riders].
Sportverletzung Sportschaden : Organ der Gesellschaft fur Orthopadisch-Traumatologische Sportmedizin    March 27, 2007   Volume 21, Issue 1 29-33 doi: 10.1055/s-2007-963038
Kraft CN, Urban N, Ilg A, Wallny T, Scharfstädt A, Jäger M, Pennekamp PH.The connection between morphologic changes of the spine and the intensity of training has been assessed for a number of sport activities. The influence of horseback riding on the spine has only rarely been evaluated. The aim of our study was to evaluate to what degree horseback riders suffer from back pain and whether there is an association between this parameter and the category i. e. the intensity of horseback riding. Furthermore we wanted to judge whether riding may have a positive effect on pre-existent back pain. Methods: 508 horseback riders (63.2 % females; 36.8 % males) competing in e...
Alteration of distal tarsal subchondral bone thickness pattern in horses with tarsal pain.
Equine veterinary journal    March 24, 2007   Volume 39, Issue 2 101-105 doi: 10.2746/042516407x166756
Branch MV, Murray RC, Dyson SJ, Goodship AE.Understanding of the development of pathology and source of pain in distal tarsal osteoarthritis is poorly understood. Magnetic resonance imaging is often used in the analysis of human osteoarthritis (OA) because it is sensitive to early changes. Objective: In association with distal tarsal joint (DTJ) pain, there will be an alteration in the characteristic subchondral bone (SCB) thickness pattern of horses with no history of pain when subjected to low-level exercise. Methods: Sixteen cadaver tarsal joints were collected from 9 mature horses with a history of tarsal pain and radiographic evide...
Field fracture management.
The Veterinary clinics of North America. Equine practice    March 24, 2007   Volume 23, Issue 1 117-133 doi: 10.1016/j.cveq.2006.11.008
Mudge MC, Bramlage LR.Emergency management of distal limb and skull fractures in horses is vital to the successful outcome of these cases. Distal limb fractures, in particular, require careful assessment and counseling of the owner as well as adequate stabilization or coaptation of the fracture. Horses with limb or skull fractures may also have concurrent pain, blood loss, and other fluid losses that can result in shock requiring fluid therapy before definitive treatment of the fracture. Proper emergency fracture stabilization, initial treatment in the field, and patient transport are discussed.
Endoscopic resection of dorsal spinous processes and interspinous ligament in ten horses.
Veterinary surgery : VS    March 6, 2007   Volume 36, Issue 2 149-155 doi: 10.1111/j.1532-950X.2007.00247.x
Desbrosse FG, Perrin R, Launois T, Vandeweerd JM, Clegg PD.To describe endoscopic surgical subtotal resection of the dorsal spinous processes (DSP) and interspinous ligament in horses. Methods: Descriptive clinical study. Methods: Adult horses (n=10) with back pain and impinging dorsal spinous processes Methods: Diseased portions of DSP and interspinous ligament were resected by endoscopic surgery, using Destandau Endospine to create a surgical space and provide triangulation for the endoscope, suction cannula, and surgical instruments. Medical records of 10 horses with pain attributable to DSP pathology treated by endoscopic resection of DSP were rev...
Canadian veterinarians’ use of analgesics in cattle, pigs, and horses in 2004 and 2005.
The Canadian veterinary journal = La revue veterinaire canadienne    March 6, 2007   Volume 48, Issue 2 155-164 doi: 10.4141/cjas68-021
Hewson CJ, Dohoo IR, Lemke KA, Barkema HW.Anecdotal evidence suggests that many veterinarians may not use analgesics in livestock for routine surgical procedures or painful disease states. To investigate this, we conducted a national mail survey of a random sample of 1431 Canadian veterinarians (response rate, 50.1%). Questions primarily concerned veterinarians' analgesic usage for common surgeries and medical conditions in beef and dairy cattle, pigs, and horses, and attitudes toward pain management. More than 90% of veterinarians used analgesic drugs for equine surgeries, for cesarean section in sows and cows, and for bovine claw am...
Effects of buprenorphine on nociception and spontaneous locomotor activity in horses.
American journal of veterinary research    March 3, 2007   Volume 68, Issue 3 246-250 doi: 10.2460/ajvr.68.3.246
Carregaro AB, Luna SP, Mataqueiro MI, de Queiroz-Neto A.To investigate spontaneous locomotor activity (SLA) and antinociceptive effects of buprenorphine in horses. Methods: 6 healthy adult horses. Methods: Horses received each of 3 treatments (10 mL of saline [0.9% NaCl] solution, 5 microg of buprenorphine/kg, or 10 microg of buprenorphine/kg). Treatments were administered IV. Order of treatments was randomized, and there was a 10-day interval between subsequent treatments. Spontaneous locomotor activity was investigated in a behavioral box by use of infrared photoelectric sensors connected to a computer, which detected movement of each horse. Anti...
Efficacy of tiludronate in the treatment of horses with signs of pain associated with osteoarthritic lesions of the thoracolumbar vertebral column.
American journal of veterinary research    March 3, 2007   Volume 68, Issue 3 329-337 doi: 10.2460/ajvr.68.3.329
Coudry V, Thibaud D, Riccio B, Audigié F, Didierlaurent D, Denoix JM.To evaluate the efficacy of tiludronate for the treatment of horses with signs of pain associated with lesions of the thoracolumbar vertebral column. Methods: 29 horses with clinical manifestations of pain associated with lesions of the thoracolumbar vertebral column and abnormal radiographic findings indicative of osteoarthritis of the articular processes-synovial intervertebral joints. Methods: Horses were initially examined in accordance with a standardized protocol, which included radiographic, ultrasonographic, and scintigraphic examinations. Fifteen horses were randomly assigned to recei...
Effects of butorphanol on the withdrawal reflex using threshold, suprathreshold and repeated subthreshold electrical stimuli in conscious horses.
Veterinary anaesthesia and analgesia    January 24, 2007   Volume 34, Issue 1 48-58 doi: 10.1111/j.1467-2995.2006.00289.x
Spadavecchia C, Arendt-Nielsen L, Spadavecchia L, Mosing M, Auer U, van den Hoven R.To assess the effects of a single intravenous dose of butorphanol (0.1 mg kg(-1)) on the nociceptive withdrawal reflex (NWR) using threshold, suprathreshold and repeated subthreshold electrical stimuli in conscious horses. Methods: 'Unblinded', prospective experimental study. Methods: Ten adult horses, five geldings and five mares, mean body mass 517 kg (range 487-569 kg). Methods: The NWR was elicited using single transcutaneous electrical stimulation of the palmar digital nerve. Repeated stimulations were applied to evoke temporal summation. Surface electromyography was performed to record a...
Ultrasound-guided coxofemoral arthrocentesis in horses.
Equine veterinary journal    January 19, 2007   Volume 39, Issue 1 79-83 doi: 10.2746/042516407x153093
David F, Rougier M, Alexander K, Morisset S.Coxofemoral joint pain is probably underestimated due to difficulties in identifying hip pain. The deep location of the joint and proximity of the sciatic nerve make arthrocentesis based on external landmarks a difficult and potentially risky procedure in mature horses. Objective: To describe an ultrasound-guided injection technique of the coxofemoral joint in standing horses and to evaluate its accuracy and potential difficulties/complications. Methods: Nine mature horses had both pelvic areas prepared for sterile ultrasound examination (3.5 MHz curvilinear probe). Coxofemoral joints were loc...
Innervation and nerve injections of the lumbar spine of the horse: a cadaveric study.
Equine veterinary journal    January 19, 2007   Volume 39, Issue 1 59-63 doi: 10.2746/042516407x153147
Vandeweerd JM, Desbrosse F, Clegg P, Hougardy V, Brock L, Welch A, Cripps P.The distal limb innervation of the horse has been studied extensively to allow use of local anaesthetic techniques to detect the origin of pain in lameness. However, the innervation of the lumbar spine has so far been poorly described and a more precise description may assist clinicians to localise back pain in the horse. Objective: To gain better knowledge of the innervation of the lumbar spine and identify salient anatomical features that might be used for diagnostic and therapeutic ultrasound guided injections. Methods: The spines of 8 mature horses were dissected. Branches of the dorsal ra...
Comparison of intraoperative pain responses following intratesticular or mesorchial injection of lidocaine in standing horses undergoing laparoscopic cryptorchidectomy.
Journal of the American Veterinary Medical Association    December 6, 2006   Volume 229, Issue 11 1779-1783 doi: 10.2460/javma.229.11.1779
Joyce J, Hendrickson DA.To compare pain responses in stallions undergoing standing laparoscopic cryptorchidectomy following intratesticular or mesorchial infiltration of lidocaine. Methods: Clinical trial. Methods: 20 stallions with 1 or 2 undescended testes. Methods: Standing horses were administered a nonsteroidal anti-inflammatory drug and a caudal epidural injection of detomidine hydrochloride and underwent laparoscopic cryptorchidectomy. The undescended testis (1/horse) was grasped to determine the preoperative pain response (present vs absent) and assess severity of pain (by use of a visual analog scale [VAS])....
Laparoscopic cryptorchidectomy and ovariectomy in horses.
The Veterinary clinics of North America. Equine practice    November 30, 2006   Volume 22, Issue 3 777-798 doi: 10.1016/j.cveq.2006.08.006
Hendrickson D.Laparoscopic surgery has become commonplace in the field of equine urogenital surgery. As with most surgical procedures, the limiting factors in developing new surgical techniques are limited to the patient size and demeanor, the skills of the surgeon, and the available equipment. Some of the greatest benefits of laparoscopic surgery in the horse include better visualization of the important structures; tension-free amputation of the testes or ovaries,which generally leads to less postoperative pain; and the ability to evaluate the transected stump carefully to make sure there is no hemorrhage...
Pressure algometry to quantify muscle pain in racehorses with suspected sacroiliac dysfunction.
Equine veterinary journal    November 28, 2006   Volume 38, Issue 6 558-562 doi: 10.2746/042516406x154804
Varcoe-Cocks K, Sagar KN, Jeffcott LB, McGowan CM.Despite the prevalence of orthopaedic injuries to horses, there is no objective means of quantifying the intensity of musculoskeletal pain. Objective: Mechanical nociceptive thresholds (MNT) can be measured repeatably by pressure algometry in horses and MNTs are correlated with both severity of clinical signs and subjective scores of muscle pain on palpation in horses with suspected sacroiliac dysfunction (SID). Methods: The technique of pressure algometry and its repeatability was tested at 4 anatomical sites on either side of the thoracolumbar and pelvic region in 12 Thoroughbreds in trainin...
Magnetic resonance imaging, ultrasonography and histology of the suspensory ligament origin: a comparative study of normal anatomy of warmblood horses.
Equine veterinary journal    November 28, 2006   Volume 38, Issue 6 508-516 doi: 10.2746/042516406x156109
Bischofberger AS, Konar M, Ohlerth S, Geyer H, Lang J, Ueltschi G, Lischer CJ.The diagnosis of lameness caused by proximal metacarpal and metatarsal pain can be challenging. Magnetic resonance imaging (MRI) offers the possibility for further diagnosis but there have been no studies on the normal MRI appearance of the origin of the suspensory ligament (OSL) in conjunction with ultrasonography and histology. Objective: To describe the MRI appearance of the OSL in fore- and hindlimbs of sound horses and compare it to the ultrasonographic and histological appearance. The findings can be used as reference values to recognise pathology in the OSL. Methods: The OSL in the fore...
MRI and CT diagnosis of acute desmopathy of the lateral collateral sesmoidean (navicular) ligament and long-term outcome in a horse.
Veterinary journal (London, England : 1997)    October 17, 2006   Volume 174, Issue 2 410-413 doi: 10.1016/j.tvjl.2006.08.003
Kofler J, Kneissl S, Malleczek D.Clinical, magnetic resonance imaging (MRI) and computed tomography (CT) findings of acute desmopathy of the lateral collateral sesmoidean (navicular) ligament (CSL) in a 13-year-old Hanoverian mare are presented. On admission to the clinic the horse showed a grade 5/6 left front-limb lameness at the walk, pain on coffin joint manipulation, and coffin joint effusion. Despite a positive palmar digital nerve block, radiographs and ultrasonography did not indicate reasons for the severe clinical signs. However, MRI revealed damage to the CSL and bone marrow oedema of the navicular bone (NB), where...
Mandibular condylectomy and meniscectomy for the treatment of septic temporomandibular joint arthritis in a horse.
Veterinary surgery : VS    October 10, 2006   Volume 35, Issue 7 663-668 doi: 10.1111/j.1532-950X.2006.00205.x
Nagy AD, Simhofer H.To report use of mandibular condylectomy for treatment of advanced degenerative joint disease of the temporomandibular joint (TMJ) caused by sepsis. Methods: Clinical case report. Methods: Two-year-old Noriker filly. Methods: Computed tomography (CT) was used to confirm advanced degenerative joint disease of the left TMJ and for follow-up after mandibular condylectomy and removal of necrotic meniscus. Results: Painful swelling (3 weeks duration) with drainage located just caudal to the left lateral canthus of the eye was associated with atrophy of the left masseter muscle, masticatory problems...
Regional differences in transdermal penetration of fentanyl through equine skin.
Research in veterinary science    October 2, 2006   Volume 82, Issue 2 252-256 doi: 10.1016/j.rvsc.2006.07.015
Mills PC, Cross SE.The rate and regional differences for the penetration of fentanyl through equine skin was investigated in vitro using a commercial transdermal therapeutic system (TTS) or 'patch'. Skin collected from the thorax, groin and leg (dorsal metacarpal) regions of five horses was placed in diffusion cells and a fentanyl TTS applied to each skin sample. Drug penetration through each skin sample over 48 h measured using high performance liquid chromatography (HPLC). Cumulative penetration (microg/cm2) was plotted against time (h) and used to regress the steady state flux (microg/cm2/h) of fentanyl throu...
Evidence of bias affecting the interpretation of the results of local anaesthetic nerve blocks when assessing lameness in horses.
The Veterinary record    September 12, 2006   Volume 159, Issue 11 346-349 doi: 10.1136/vr.159.11.346
Arkell M, Archer RM, Guitian FJ, May SA.Eighteen observers were influenced to different extents in the grades of lameness they allocated to eight horses by whether they knew that a nerve block had been administered; on a scale from 0 to 10 the mean difference in grade allocated once the observer knew a horse had been nerve-blocked was increased by 0.4. The consistency of the assessments made by the individual observers was good, with a an average of 0.6 of a grade difference when grading the same horse on two occasions. The agreement between the assessments of four orthopaedic experts was reasonable (+/-1 grade), but significantly p...
Suspected complex regional pain syndrome in 2 horses.
Journal of veterinary internal medicine    September 8, 2006   Volume 20, Issue 4 1014-1017 doi: 10.1892/0891-6640(2006)20[1014:scrpsi]2.0.co;2
Collins NM, Keen JA, Barakzai SZ, Mayhew IG, McGorum BC.No abstract available
Use of magnetic resonance imaging to diagnose distal sesamoid bone injury in a horse.
Journal of the American Veterinary Medical Association    September 5, 2006   Volume 229, Issue 5 717-720 doi: 10.2460/javma.229.5.717
Barber MJ, Sampson SN, Schneider RK, Baszler T, Tucker RL.A 5-year-old Appaloosa mare was examined for severe left forelimb lameness of 4 months' duration. Results: Lameness was evident at the walk and trot and was exacerbated when the horse circled to the left. Signs of pain were elicited in response to hoof testers placed over the frog of the left front hoof, and a palmar digital nerve block eliminated the lameness. Radiographs revealed no abnormalities, but magnetic resonance imaging (MRI) revealed increased bone density in the medullary cavity of the distal sesamoid (navicular) bone in the proton density and T2-weighted images and a defect in the...
Prevalence of gastric squamous ulceration in horses with abdominal pain.
Equine veterinary journal    July 27, 2006   Volume 38, Issue 4 347-349 doi: 10.2746/042516406777749164
Dukti SA, Perkins S, Murphy J, Barr B, Boston R, Southwood LL, Bernard W.Prevalence of gastric ulcerations differs widely according to breed and circumstances of management. Further study of the biological variables involved is required in order to identify more exactly the reasons for the reported range. Objective: The objectives of this present study, which do not appear to have been addressed previously in the literature, were 1) the prevalence of gastric ulceration in horses with abdominal pain. 2) difference in prevalence in horses responding to medical therapy and those requiring surgical intervention. 3) whether gastric ulceration is associated with any part...
Arthrogenic lameness of the fetlock: synovial fluid markers of inflammation and cartilage turnover in relation to clinical joint pain.
Equine veterinary journal    July 27, 2006   Volume 38, Issue 4 305-311 doi: 10.2746/042516406777749236
de Grauw JC, van de Lest CH, van Weeren R, Brommer H, Brama PA.Joint pain is one of the most common causes of lameness in the horse but its pathogenesis is poorly understood. Objective: To investigate which synovial fluid markers may be related to the presence of clinically detectable joint pain in the horse. Methods: Concentrations of structural (CPII, C2C, GAG) and inflammatory markers (PGE2, LTB4, CysLTs, bradykinin and substance P) were measured in fetlock joint fluid from 22 horses in which lameness was localised to the fetlock region by perineural anaesthesia. Levels of these markers were then compared in horses that responded (n = 15) to those that...
Risk factors for colic in horses after general anaesthesia for MRI or nonabdominal surgery: absence of evidence of effect from perianaesthetic morphine.
Equine veterinary journal    July 27, 2006   Volume 38, Issue 4 368-374 doi: 10.2746/042516406777749263
Andersen MS, Clark L, Dyson SJ, Newton JR.Post anaesthetic colic is a recognised risk of general anaesthesia (GA), but causes are poorly understood. Objective: To identify risk factors for development of colic following GA for magnetic resonance imaging (MRI) or nonabdominal surgery and to test whether the use of perianaesthetic morphine was associated with an increased risk of post anaesthetic colic. Methods: A total of 553 anaesthetic and clinical records of 500 horses anaesthetised at the Animal Health Trust were analysed, 342 (62%) involved MRI and 211 (38%) nonabdominal, predominantly orthopaedic surgery. Multivariable logistic r...
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