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Topic:Parasites

Parasites are organisms that live on or within a host, deriving nutrients at the host's expense. In horses, parasitic infections can affect various systems, including the gastrointestinal tract, skin, and respiratory system. Common equine parasites include strongyles, ascarids, tapeworms, and bots. These parasites can lead to a range of health issues, from mild discomfort to severe disease, depending on the type and burden of the infestation. This page compiles peer-reviewed research studies and scholarly articles that explore the biology, life cycle, and impact of parasites on equine health, as well as strategies for diagnosis, treatment, and prevention of parasitic infections in horses.
Comparison of the efficacy of ivermectin, oxibendazole, and pyrantel pamoate against 28-day Parascaris equorum larvae in the intestine of pony foals.
Journal of the American Veterinary Medical Association    June 11, 1991   Volume 198, Issue 11 1946-1949 
Austin SM, DiPietro JA, Foreman JH, Baker GJ, Todd KS.Sixteen helminth-free pony foals were inoculated with a mean (+/- SD) 2,000 (+/- 545.5) infective Parascaris equorum eggs (day 0). Foals were allocated to replicates of 4, and treatments within each replicate were assigned at random. Treatment administered on postinoculation day (PID) 28 included no treatment (control), 0.2 mg of ivermectin/kg of body weight, 10 mg of oxibendazole/kg, or 6.6 mg of pyrantel base (pamoate)/kg. Paste formulations of the anthelmintics were administered orally. The foals were euthanatized 14 days after treatment (PID 42) and examined for P equorum larvae in the sma...
DNA probes for the detection of Babesia caballi.
Parasitology    June 1, 1991   Volume 102 Pt 3 357-365 doi: 10.1017/s0031182000064301
Posnett ES, Ambrosio RE.A genomic library of Babesia caballi DNA was constructed in the plasmid vector pUC13. The specificity of the clones for B. caballi was established by the lack of hybridization to Babesia equi, Babesia bovis, Babesia bigemina and equine DNA. Two probes, pBC11 and pBC191, were isolated that could detect 0.25 ng and 0.125 ng of B. caballi DNA, corresponding to a parasitaemia of 0.12% and 0.06% respectively. pBC191 could detect B. caballi parasites in the blood of an experimentally infected horse as well as in naturally infected horses.
Medical problems of adult horses, as ranked by equine practitioners.
Journal of the American Veterinary Medical Association    May 15, 1991   Volume 198, Issue 10 1745-1747 
Traub-Dargatz JL, Salman MD, Voss JL.This paper reports the results of a survey conducted among members of the American Association of Equine Practitioners, concerning medical problems of adult horses. A one-page questionnaire listing 36 medical problems grouped by body system was completed by 1,149 veterinarians. The top-ranked disease was colic, followed by viral respiratory tract disease, endometritis, dermatitis, and parasitism. When responses were evaluated by type of practice, location of practice, and number of veterinarians in the practice, ranking of the top 2 diseases was the same for the total respondents. Ranking of d...
Preliminary observations on an alternative strategy for the control of horse strongyles.
Equine veterinary journal    May 1, 1991   Volume 23, Issue 3 226-228 doi: 10.1111/j.2042-3306.1991.tb02762.x
Duncan JL, Love S.No abstract available
Equine helminth infections: control by selective chemotherapy.
Equine veterinary journal    May 1, 1991   Volume 23, Issue 3 198-200 doi: 10.1111/j.2042-3306.1991.tb02754.x
Gomez HH, Georgi JR.A programme of selective anthelmintic therapy was used in a herd of 31 horses. Faecal egg counts were done during the months of September, November, January, March, May and the following September. Horses with greater than or equal to 100 eggs per gram (epg) were treated with ivermectin, and those with less than 100 epg were not treated. The criteria for adequate internal parasite control in the herd was a median herd faecal egg count of less than or equal to 100 epg. Effectiveness of selective therapy was assessed by faecal egg count after nine months of treatment and was determined to be ade...
Could the worms have turned?
Equine veterinary journal    May 1, 1991   Volume 23, Issue 3 152-154 doi: 10.1111/j.2042-3306.1991.tb02745.x
Love S, Duncan JL.No abstract available
[Possibilities and limits of immunodiagnosis of strongyle infections in horses].
Berliner und Munchener tierarztliche Wochenschrift    May 1, 1991   Volume 104, Issue 5 149-153 
Weiland G, Hasslinger MA, Mezger S, Pöllein W.In an investigation period over 8 months the natural course of infection was studied by means of coproscopic and serological methods in 27 mares and 29 foals. The examination of the stool showed in mares, before the beginning of the grazing season, an infection rate of 100% with small and a rate of 7.4% with large strongyles (Str. vulgaris). Serologically the ELISA showed in foals only a distinct increase of antibody activity with the somatic antigen. The mares retained the high IgG-values of activity, which were already found at the beginning of the investigations. Even though the agglutinati...
Verminous mastitis in a mare caused by a free-living nematode.
The Journal of parasitology    April 1, 1991   Volume 77, Issue 2 320-322 
Greiner EC, Mays MB, Smart GC, Weisbrode SE.Verminous mastitis was the reason for euthanasia of a 22-yr-old Paso Fino mare from Miami, Florida. The etiologic agent was a species of Cephalobus (Rhabditida: Cephalobidae), a genus of soil-inhabiting nematodes that were obviously multiplying in the mammary gland. Only females and larvae were detected in the tissues by histologic section or by teasing the tissue to liberate the worms. At least 12,900 individuals were present per gram of tissue. This is the first case of Cephalobus infecting horses and it indicates that not all histiotropic infections of horses by rhabditoid nematodes are by ...
Controlled test evaluation of the benzimidazole anthelmintic VET 220-S alone or with concomitant trichlorfon treatment against naturally acquired gastrointestinal parasites in ponies.
American journal of veterinary research    April 1, 1991   Volume 52, Issue 4 566-569 
Bello TR.A controlled test was done in 30 naturally infected ponies to evaluate the antiparasitic activity of the dienbendazole analog VET 220-S given alone or with trichlorfon (TCF) by nasogastric intubation. Six ponies were nontreated; 6 were given VET 220-S (5.0 mg/kg); 6 were given TCF (40 mg/kg); 6 were given VET 220-S (2.5 mg/kg) and TCF (40 mg/kg); and 6 were given VET 220-S (5.0 mg/kg) and TCF (40 mg/kg). All ponies were euthanatized and necropsied 7 or 8 days after treatment. Draschia megastoma, Oxyuris equi, Strongylus vulgaris, S edentatus, and small strongyles were removed efficaciously by ...
Sarcocystis neurona n. sp. (Protozoa: Apicomplexa), the etiologic agent of equine protozoal myeloencephalitis.
The Journal of parasitology    April 1, 1991   Volume 77, Issue 2 212-218 
Dubey JP, Davis SW, Speer CA, Bowman DD, de Lahunta A, Granstrom DE, Topper MJ, Hamir AN, Cummings JF, Suter MM.Sarcocystis neuronan n. sp. is proposed for the apicomplexan taxon associated with myeloencephalitis in horses. Only asexual stages of this parasite presently are known, and they are found within neuronal cells and leukocytes of the brain and spinal cord. The parasite is located in the host cell cytoplasm, does not have a parasitophorous vacuole, and divides by endopolygeny. Schizonts are 5-35 microns x 5-20 microns and contain 4-40 merozoites arranged in a rosette around a prominent residual body. Merozoites are approximately 4 x 1 micron, have a central nucleus, and lack rhoptries. Schizonts...
A field evaluation of anthelmintics for control of cyathostomes of horses in Brazil.
Veterinary parasitology    March 1, 1991   Volume 38, Issue 2-3 121-129 doi: 10.1016/0304-4017(91)90122-c
Pereira MC, Kohek Júnior I, Campos R, Lima SB, Foz RP.The anthelmintic efficacy of ivermectin (IVM), piperazine citrate (PPZ) and fenbendazole (FBZ) alone, and combinations of FBZ with varying dosages of PPZ, was evaluated for the control of strongyles of Mangalarga equids. In all cases of positive strongly egg counts per gram of faeces (EPG) before and after treatment, pure populations of cyathostome larvae with eight gut cells were consistently observed in faecal cultures. The faecal egg count reductions (FECR) were evaluated between Day 7 and Day 56 post-treatment. Significant differences (P less than or equal to 0.05) were found between Day 7...
Trypanosoma evansi infection in cattle, buffaloes and horses in Indonesia.
Veterinary parasitology    March 1, 1991   Volume 38, Issue 2-3 109-119 doi: 10.1016/0304-4017(91)90121-b
Payne RC, Sukanto IP, Djauhari D, Partoutomo S, Wilson AJ, Jones TW, Boid R, Luckins AG.Cattle, buffaloes and horses in several areas of Indonesia were examined for evidence of infection with Trypanosoma evansi by the microhaematocrit centrifugation technique (MHCT) and an enzyme-linked immunosorbent assay (ELISA) for detection of antibodies to T. evansi. Evidence of infection was found in animals at each sampling site although differences were seen in prevalence rates between sites. Prevalence rates in buffalo were usually higher than in cattle in the same area while in horses they were much lower than in cattle or buffalo. An age-dependent prevalence rate was seen in buffalo an...
Equine neural angiostrongylosis.
Australian veterinary journal    February 1, 1991   Volume 68, Issue 2 58-60 doi: 10.1111/j.1751-0813.1991.tb03131.x
Wright JD, Kelly WR, Waddell AH, Hamilton J.Verminous encephalomyelitis due to Angiostrongylus cantonensis larvae was diagnosed in 2 foals at necropsy. The principal clinical feature was tetraparesis, although history and neurological examination revealed progressive and multifocal neurological disease. At presentation, a tentative diagnosis of parasitic larval migration involving the central nervous system (CNS), presumably due to Strongylus vulgaris, was proposed. Dissection of the spinal cord in one case resulted in recovery of intact larvae of both sexes of A. cantonensis. In both foals, histopathology of the brain and spinal cord r...
Comparison of ivermectin, oxibendazole, and pyrantel pamoate in suppressing fecal egg output in horses.
The Canadian veterinary journal = La revue veterinaire canadienne    February 1, 1991   Volume 32, Issue 2 104-107 
Piché CA, Kennedy MJ, Herbers HA, Newcomb KM.Thirty resident horses at a boarding stable in Alberta were used to evaluate the relative efficacies of ivermectin, oxibendazole, and pyrantel pamoate in reducing fecal egg output in adult horses under routine management conditions during spring and early summer, and to more clearly define the duration of suppression of fecal egg production following anthelmintic treatment. Horses were blocked according to pretreatment egg counts and randomly assigned to one of three treatments: pyrantel pamoate at 6.6 mg/kg body weight; oxibendazole at 10 mg/kg body weight; or ivermectin at 200 mug/kg body we...
Immunohistochemical diagnosis of protozoan parasites in lesions of equine protozoal myeloencephalitis. Granstrom DE, Giles RC, Tuttle PA, Williams NM, Poonacha KB, Petrites-Murphy MB, Tramontin RR, Swerczek TW, Hong CB, Rezabek GB.No abstract available
Enrichment of Babesia caballi-infected erythrocytes from microaerophilous stationary-phase cultures using Percoll gradients.
Parasitology research    January 1, 1991   Volume 77, Issue 2 177-179 doi: 10.1007/BF00935433
Bhushan C, Müller I, Friedhoff KT.A rapid and simple method for concentrating leucocyte-free Babesia caballi-infected erythrocytes from in vitro cultures is described. Infected erythrocytes amounted to at least 95% of all red cells obtained.
Resistance to benzimidazole anthelmintics in small strongyles (Cyathostominae) of horses in Denmark.
Acta veterinaria Scandinavica    January 1, 1991   Volume 32, Issue 2 253-260 doi: 10.1186/BF03546987
Bjørn H, Sommer C, Schougård H, Henriksen SA, Nansen P.This study was undertaken to establish whether anthelmintic resistance was present in nematode parasites of horses in Denmark. Sixteen horse farms were selected for faecal egg count reduction (FECR) tests to measure the efficacy of the anthelmintic used. Resistance to benzimidazole anthelmintics was found on 13 of the 16 farms, with FECR values ranging from 80.0% to -101.3%. On the remaining 3 farms FECR was 100.0%, 99.3% and 97.2%. Results of a questionnaire study on anthelmintic usage, parasite control measures and management practices showed that horses in this study were treated on average...
[The epidemiology of gasterophilosis of horses in Switzerland].
Schweizer Archiv fur Tierheilkunde    January 1, 1991   Volume 133, Issue 9 409-416 
Brocard P, Pfister K.Between March 1988 and December 1989, 198 gastrointestinal tracts from slaughtered horses from different areas of Switzerland have been analysed for the presence and the frequency of Gasterophilus spp. During the same period--always between July and November--200 horses from selected areas of Western Switzerland have been checked for the presence of eggs and their subsequent developmental stages in order to investigate further clinical and biological aspects of this infection. The evaluation has been performed according to origin, age, sex, colour of the horse and seasonal pattern of the cases...
Parahost behavior of adult Gasterophilus intestinalis (Diptera: Gasterophilidae) in Delaware.
Journal of medical entomology    January 1, 1991   Volume 28, Issue 1 67-73 doi: 10.1093/jmedent/28.1.67
Cope SE, Catts EP.Parahost behavior of adult Gasterophilus intestinalis (DeGeer) was observed during the summers of 1978 and 1979 near pastured horses on two farms near Newark, Del. Adult fly occurrence, although sparse in early summer, indicated a gradual increase, with three surges in emergence. In the laboratory, males lived 1-3 d and females 1-2 d. In the field, marked flies were not seen on days following their release. Adult behavior indicated an urgency in mating and oviposition dictated by a short life span. Male flight patterns were characterized by in-flight searches for females and intraspecific conf...
Effect of early season ivermectin and pyrantel treatments on strongylid infections in young Shetland ponies in The Netherlands.
Veterinary parasitology    January 1, 1991   Volume 38, Issue 1 33-39 doi: 10.1016/0304-4017(91)90005-g
Eysker M, Boersema JH, Kooyman FN.Two groups of three ponies were used to study the effect of three ivermectin or pyrantel treatments given at intervals of 5 weeks at the beginning of the grazing season. Although each pyrantel treatment resulted in a greater than 95% reduction in faecal egg counts during the first 3 weeks, high pasture larval counts were seen from the beginning of August onwards and substantial cyathostomine burdens were found at necropsy in December. The ivermectin treatments resulted in an even more pronounced reduction in faecal egg output, and the pasture larval counts and cyathostomine burdens at necropsy...
Rhodococcus equi: an animal and human pathogen.
Clinical microbiology reviews    January 1, 1991   Volume 4, Issue 1 20-34 doi: 10.1128/CMR.4.1.20
Prescott JF.Recent isolations of Rhodococcus equi from cavitatory pulmonary disease in patients with AIDS have aroused interest among medical microbiologists in this unusual organism. Earlier isolations from humans had also been in immunosuppressed patients following hemolymphatic tumors or renal transplantation. This organism has been recognized for many years as a cause of a serious pyogranulomatous pneumonia of young foals and is occasionally isolated from granulomatous lesions in several other species, in some cases following immunosuppression. The last decade has seen many advances in understanding o...
Comparison of three anthelmintics in the control of intestinal nematodes in young horses on fall and winter pasture.
The Canadian veterinary journal = La revue veterinaire canadienne    December 1, 1990   Volume 31, Issue 12 841-843 
Piché CA, Kennedy MJ, Bauck SW, Goonewardene L.No abstract available
[Etiology and occurrence of periodic eye inflammation of horses in the area of Berlin].
Tierarztliche Praxis    December 1, 1990   Volume 18, Issue 6 623-627 
Alexander CS, Keller H.Over 130 cases of equine periodic ophthalmia (p.o.), which were treated as in-patients at the Equine Clinic of the Free University of Berlin in the last 35 years, were examined statistically in relation to the age and gender of the animals involved as well as to the development of the illness and the season in which it arose. As regards aetiology, the extraction of 71 affected Trotters was investigated. Antibodies to toxoplasmosis, leptospirosis and intestinal parasites were found only in some of the patients. Younger animals, aged between one and four years, and male animals (63.6%) were pred...
Haemoparasites of equines: impact on international trade of horses.
Revue scientifique et technique (International Office of Epizootics)    December 1, 1990   Volume 9, Issue 4 1187-1194 
Friedhoff KT, Tenter AM, Müller I.The geographical distribution of Babesia equi and Babesia caballi and their tick vectors is discussed. Control of infections with these protozoa is hampered by the lack of a suitable antiprotozoal drug and a reliable serological test. No vaccine is available. Ehrlichia risticii (the causal agent of Potomac horse fever) and E. equi are rickettsial parasites which are difficult to control. Little is known of their geographical distribution and vectors. Early diagnosis is required for tetracycline therapy to be effective and there is a need for a rapid test to provide an early diagnosis.
Efficacy of avermectin B1 given orally against equine intestinal strongyles and Onchocera microfilaria.
Australian veterinary journal    November 1, 1990   Volume 67, Issue 11 399-401 doi: 10.1111/j.1751-0813.1990.tb03026.x
Mogg TD, Pollitt CC, Willmore JP, Thompson H.Three groups of horses and ponies (N = 13, 13 and 12) were treated with ivermectin paste (0.2 mg/kg p.o.), avermectin B1 solution (0.2 mg/kg p.o.), or fenbendazole suspension (10 mg/kg via nasogastric tube). The avermectin B1 was a 1% solution in a propylene glycolglycerol formal base. Faecal strongyle egg counts were performed before, and 14, 28, 42, 56 and 70 d, after treatment. Full-thickness skin biopsies from the neck, pectoral and umbilical regions were examined for Onchocera microfilaria before treatment, and again 14 and 70 d later. Ivermectin therapy produced a significant (P less tha...
Histological and ultrastructural appearance of severe Sarcocystis fayeri infection in a malnourished horse. Cawthorn RJ, Clark M, Hudson R, Friesen D.No abstract available
[Epidemiology, chemotherapy, anthelmintics-resistance and prevention of Strongylidae infections in horses].
Tijdschrift voor diergeneeskunde    October 1, 1990   Volume 115, Issue 19 891-907 
Eysker M, Vercruysse J.The epidemiology, chemotherapy and control of strongylus infections in the horse are discussed. The annual cycle of various species are stated. In addition the anthelmintics available for treatment and control and the occurrence of anthelmintic resistance are referred to. Finally the options for control under various management conditions (little if any grazing; extensive grazing; intensive grazing) are discussed.
Neospora caninum (Apicomplexa) in an aborted equine fetus.
The Journal of parasitology    October 1, 1990   Volume 76, Issue 5 732-734 
Dubey JP, Porterfield ML.Tachyzoites of Neospora caninum were found in sections of lung of an equine fetus aborted 2 mo before term. Individual tachyzoites were approximately 3-5 x 2-3 microns, divided by endodyogeny, and stained positively with anti-N. caninum serum but not with anti-Toxoplasma gondii serum. Toxoplasma gondii antibody was not found in the mare's serum. This is the first report of N. caninum in a horse and indicates that N. caninum can be transmitted transplacentally in equids.
Production of interleukin 2 and expression of interleukin 2 receptors by pony peripheral blood lymphocytes after stimulation with a soluble fraction of Trypanosoma evansi.
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B    October 1, 1990   Volume 37, Issue 8 631-637 doi: 10.1111/j.1439-0450.1990.tb01107.x
Ahmed JS, Schmid G, Hörchner F.Pony peripheral blood lymphocytes (PBL) were stimulated with a soluble fraction of Trypanosoma (T.) evansi (SF). As determined by 3H-thymidine incorporation, the cells underwent a proliferative response and were able to: a) produce a factor having the biological activities of interleukin 2 (IL-2) since their supernatants could support the in vitro growth of pony PBL stimulated with concanavalin A (Con A-blasts); b) undergo a further proliferative response when incubated in short term cultures with SF, human recombinant IL-2 (hrIL-2), or both c) bind specifically radiolabelled hrIL-2 (125I-hrIL...
Field investigation of anthelmintic resistance of small strongyles in horses.
The Veterinary record    September 1, 1990   Volume 127, Issue 9 232-233 
King AI, Love S, Duncan JL.No abstract available
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