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Topic:Physiology
The physiology of horses encompasses the study of the biological functions and processes that occur within the equine body. This includes the examination of various systems such as the cardiovascular, respiratory, musculoskeletal, digestive, and nervous systems. Understanding equine physiology is essential for comprehending how horses adapt to different environmental conditions, perform physical activities, and respond to health challenges. Research in this field often focuses on the mechanisms of energy metabolism, thermoregulation, and muscle function during exercise, as well as the physiological responses to stress and disease. This page compiles peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine physiology, providing insights into the biological processes that support the health and performance of horses.
[Preliminary study of the effect of supplementation of iron, copper, cobalt and zinc on cellulolytic activity in the cecum of the pony]. We studied a caecum-cannulated pony fed hay libitum in order to determine the mineral elements likely to cause deficiencies which decrease microbial activity in the caecum. During four successive 1-month periods, we observed the effects of adding 50 mg of iron, 1 mg of cobalt, 40 mg of copper and 200 mg of zinc, respectively. Except for the introduction of zinc, which greatly diminishes cellulolytic activity measured with the nylon bag technique, there was no significant modification in that activity as shown by pH, NH3-nitrogen, total nitrogen and volatile fatty acid production (table 1). It ...
The effect of benzo(a)pyrene on fertility, primordial oocyte number, and ovarian response to pregnant mare’s serum gonadotropin. The polycyclic aromatic hydrocarbon (PAH) benzo(a)pyrene (BP) reduced the fertility of DBA/2N mice in a dose-dependent fashion. Control mice produced offspring at a rate of 0.91 pups/mouse per week. Treatment with BP at doses of 10, 100, 200, and 500 mg/kg decreased offspring production rates to 0.61, 0.20, zero and zero pups/mouse per week, respectively. BP also destroyed primordial oocytes in similarly treated mice. Treatment with BP at doses of 10, 50, 100, and 500 mg/kg destroyed 20%, 58%, 88%, and 100%, respectively, of the primordial oocytes in DBA/2N mouse ovaries. Dose-response curves ...
Estrus, ovulation, and serum hormones in mares given prostaglandin F2 alpha, estradiol, and gonadotropin-releasing hormone. A gonadotropin-releasing hormone (GnRH) was injected in mares given prostaglandin F2 alpha (PGF2 alpha) to induce luteolysis in an attempt to sunchronize ovulation. Pretreatment with estradiol-17 beta (E2-17 beta) was used to determine whether or not estradiol would enhance the release of luteinizing hormone (LH) after treatment with GnRH. Twelve mares were used in a balanced Latin square crossover design. Mares were injected with PGF2 alpha, treatment A; PGF2 alpha mgnRH, treatment B; or PGF2 alpha me2-17 beta mgnRH, treatment C. The interval +/- SEM from PGF2 alpha injection to estrus was 3....
Concentration of serum prealbumin (PR) protein in sick horses and its correlation to blood leucocyte count and albumin content in serum. Studies of Pr protein concentrations in sera of sick horses were carried out using ’s (1965) immunodiffusion technique. Relative values against a chosen standard of 100 were determined for a total of 102 horses. Horses with acute infections had Pr protein values significantly above the normal. The highest individual Pr protein value recorded in this group was 202. Horses suffering from acute laminitis and malignant tumours also had increased Pr protein values. There was a positive correlation between the Pr protein value and the blood leucocyte count and a negative correlation between the P...
[Effect of the distribution of hay and cereals on the cellulolytic activity in the large intestine of the pony]. The cellulolytic activity in the large intestine of the pony varies according to the form and the composition of the feed. This activity was measured on two caecal and ventral colon-cannulated ponies receiving the following 4 diets during four successive 6-week periods: --6 kg of hay, --4 kg of hay + 1 kg of oats, --6 kg of ground, pelleted hay. --5 kg of a ground, pelleted blend of 80 p. 100 hay and 20 p. 100 oats. Adding oats to a hay feed increased the cellulolytical activity in the caecum and the colon, whereas grinding and pelleting hay alone or hay enriched with oats diminished that acti...
Topographic antigenic determinants on cytochrome c. Immunoadsorbent separation of the rabbit antibody populations directed against horse cytochrome. Seven populations of site-specific antibodies were isolated from each of three sera of rabbits immunized against glutaraldehyde-polymerized horse cytochrome c. The antibodies were separated using an immunoadsorption scheme which employed the following cytochromes c: horse, beef, guanaco, rabbit, mouse testicular, pigeon, and the cyanogen-bromide cleaved fragment of the rabbit protein containing residues 1 to 65. The monovalent, antigen-binding fragments of the antibodies (Fab') gave 1:1 stoichiometries with native horse cytochrome c in fluorescence quenching assays. Cross-reactivities with het...
The growth of the transverse sectional area (TSA) of M. semitendinosus in the dog and horse and its relation to athletic ability in the two species. The acceleration capacity of an animal determines its length of stride and hence influences its maximum running speed (GuNN, 1975 a). This is related to the potential force of its propulsive muscles relative to its live-weight. Intensive selection over the generations has produced the Greyhound and Thoroughbred horse, breeds renowned for their ability to run at greater speeds than other members of their species (CLARKE, 1965; WENTWORTH, 1957). This study describes the relationship of TSA of m. semitendinosus (represen-tative of the propulsive muscles of the hindlimb (GUNN, 1975 b) to live-weig...
Metabolism of progesterone by placentas from several mammalian species in vitro. 20-alpha-Hydroxysteroid oxidoreductase (20-alpha-HSDH) activity and 20-alpha-dihydroprogesterone concentration (20-alpha-DHP) reach peak values in the human placenta after vaginal delivery. To determine if these findings are unique to the human, we measured 20-alpha-HSDH activity as well as endogenous progesterone (P) and 20-alpha-DHP concentration in the soluble supernatant fraction of placental tissues obtained from rodents (rat, rabbit, guinea pig), ungulates (horse, zebra, giraffe, cow), and primates (squirrel monkey, orangutan, man). P concentration was very low in rodents (mean 0.60 ng/m...
Metabolic and physiological effects of adrenoceptor agonists and antagonists in the horse. In the horse the effect of the adrenergenic agonists adrenaline, phenylephrine and salbutamol on haematocrit, plasma free fatty acid, glycerol and lactate levels were investigated. Effects on heart rate, sweating and muscle tremor were also studied. The effects of administration of the adrenoceptor antagonists propranolol, metoprolol, H35/25 and acepromazine on adrenaline-induced changes were examined. The results obtained with these agonists and antagonists suggest that the lipolysis and hyperglycaemia are mediated via beta-adrenoceptors. It appears that both beta1 and beta2 subtypes are invo...
The location of eggs retained in the oviducts of mares. The oviducts of 24 mares were examined to determine the site of retention of unfertilized eggs. The ampullary-isthmic junction regions of 42 of the 48 oviducts were serially sectioned and examined histologically. The remaining parts of the oviducts were flushed and the flushings searched microscopically. Of 45 eggs located, 40 were in the sectioned segments of 24 oviducts and only 5 were in the flushings. All but one of the sectioned segments contained prominent masses of material obstructing the lumen, but these were apparently not the direct cause of egg retention since eggs were found on bo...
Minimal changes in blood cell counts and biochemical values associated with prolonged isoflurane anesthesia of horses. The potential toxicity to horses of 7.33 +/- 0.87 SD minimal alveolar concentration hours of isoflurane anesthesia was evaluated by sequential determination of blood cell counts, electrolyte concentrations, and certain blood chemical values. Minimal or no serious toxicosis was observed for up to 7 days after anesthesia was terminated.
Isoenzymes of equine alkaline phosphatase. Alkaline phosphatase isoenzymes from small intestine, cecum, large colon, small colon, liver, kidney, leukocytes, and serum from ten clinically normal horses were defined by their sensitivities to L-phenylalanine, L-homoarginine, levamisole and heat, and by polyacrylamide gel disc electrophoresis. Readily identifiable isoenzymes occurred in small intestine, granulocytes, kidney, cecum, and large and small colon. By contrast, alkaline phosphatases from liver, lymphocytes, and serum could not be discriminated by this group of tests.
[The proportion of aerobic and anaerobic metabolism in horses during graduated physical loading]. Changes in the concentration of lactate in the blood are described as a response to gradated physical strain, consisting of 1140 m of walk, 2 x 1000 m of trot, and 3 x x 5000 m of gallop in seven horses in thirteen experiments. The dependence of lactate concentration on speed in different track sections was examined and the aerobic and anaerobic stages of metabolism were clearly differentiated. It appears realistic on the basis of the onset and course of anaerobic metabolism to work out tests for evaluating the physical capacities and training abilities of horses.
