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Topic:Post-Operative Period

The post-operative period in horses refers to the timeframe following surgical procedures during which the animal undergoes recovery and rehabilitation. This period involves careful monitoring and management to ensure proper healing and to minimize complications. Key aspects of the post-operative period include pain management, wound care, and the prevention of infections. Horses may require restricted movement, dietary adjustments, and regular veterinary evaluations to assess recovery progress. This page compiles peer-reviewed research studies and scholarly articles that explore the management strategies, physiological responses, and outcomes associated with the post-operative period in equine patients.
Cardiopulmonary effects of dexmedetomidine and ketamine infusions with either propofol infusion or isoflurane for anesthesia in horses.
Veterinary anaesthesia and analgesia    July 2, 2014   Volume 42, Issue 1 39-49 doi: 10.1111/vaa.12194
Duke-Novakovski T, Palacios-Jimenez C, Wetzel T, Rymes L, Sanchez-Teran AF.To examine the cardiopulmonary effects of two anesthetic protocols for dorsally recumbent horses undergoing carpal arthroscopy. Methods: Prospective, randomized, crossover study. Methods: Six horses weighing 488.3 ± 29.1 kg. Methods: Horses were sedated with intravenous (IV) xylazine and pulmonary artery balloon and right atrial catheters inserted. More xylazine was administered prior to anesthetic induction with ketamine and propofol IV. Anesthesia was maintained for 60 minutes (or until surgery was complete) using either propofol IV infusion or isoflurane to effect. All horses were admi...
Effects of staple size, tissue thickness, and precompression time on staple shape in side-to-side jejunocecal anastomosis in specimens obtained from healthy horses at an abattoir.
American journal of veterinary research    June 25, 2014   Volume 75, Issue 7 680-684 doi: 10.2460/ajvr.75.7.680
Giusto G, Gandini M, Amedeo S.To determine effects of staple size, precompression time, and tissue thickness on staple shape and tissue approximation in side-to-side jejunocecal anastomosis in equine specimens. Methods: Cecum, ileum, and jejunum specimens obtained from 18 healthy horses at an abattoir. Methods: Specimens were allotted into 2 groups. Anastomoses were stapled with 4.8-or 3.8-mm staples. Precompression time was 15 seconds for both groups. Staple lines were cut into proximal, middle, and distal sections. Thickness of intestinal walls was measured with a calibrated tissue micrometer, photographs were obtained, ...
Two-step surgery combining standing laparoscopy with recumbent ventral median celiotomy for removal of enlarged pathologic ovaries in 20 mares.
Veterinary surgery : VS    June 24, 2014   Volume 43, Issue 6 663-667 doi: 10.1111/j.1532-950X.2014.12229.x
Vitte A, Rossignol F, Mespoulhes-Rivière C, Lechartier A, Röecken M.To report a combination of standing laparoscopic technique for intra-abdominal dissection of the mesovarial pedicle followed by a limited ventral median celiotomy under general anesthesia for removal of enlarged ovaries in mares. Methods: Case series. Methods: Mares (n = 20) aged 3-22 years with unilateral enlarged ovaries. Methods: Enlarged ovaries were confirmed by transrectal palpation and ultrasonography. After sedation, 3 laparoscopic portals were made in the paralumbar fossa. The mesovarium was desensitized and dissected using a vessel sealing device, and the ovary was left free in t...
Surgical treatment of equine colic – a retrospective study of 297 surgeries in Norway 2005-2011.
Acta veterinaria Scandinavica    June 16, 2014   Volume 56, Issue 1 38 doi: 10.1186/1751-0147-56-38
Wormstrand BH, Ihler CF, Diesen R, Krontveit RI.Colic, defined as pain originating from the abdomen, is a common condition in horses. Most of the cases resolve spontaneously or after medical treatment, but a few require surgical treatment. Surgical treatment of colic in horses is resource-demanding and expensive, and information on prognosis is therefore important for both owners and surgeons. In the present study, surgical cases in two equine hospitals in Norway between 2005 and 2011 were reviewed. The aim of the study was to describe associations between prognostic indicators, diagnoses and short term survival by use of random effects log...
Sinusitis associated with nasogastric intubation in 3 horses.
The Canadian veterinary journal = La revue veterinaire canadienne    June 4, 2014   Volume 55, Issue 6 554-558 
Nieto JE, Yamout S, Dechant JE.Sinusitis has not been reported as a complication of long-term nasogastric intubation in horses. We describe 3 horses that developed nosocomial sinusitis following abdominal surgery with associated perioperative nasogastric intubation. Sinusitis was suspected by the presence of malodorous discharge and confirmed by percussion, upper airway endoscopy, radiographs (n = 3), and bacterial culture (n = 1). La sinusite n’a a pas été signalée comme une complication de l’intubation naso-gastrique à long terme chez les chevaux. Nous décrivons 3 chevaux qui ont développé une sinusite nosocom...
Racing performance of Thoroughbreds with superficial digital flexor tendonitis treated with desmotomy of the accessory ligament of the superficial digital flexor tendon: 332 cases (1989-2003).
Journal of the American Veterinary Medical Association    May 30, 2014   Volume 244, Issue 12 1441-1448 doi: 10.2460/javma.244.12.1441
Hu AJ, Bramlage LR.To assess postoperative probability of racing, career longevity, and convalescent time in Thoroughbred racehorses with moderate to severe superficial digital flexor tendonitis (SDFT) in the forelimbs treated by desmotomy of the accessory ligament of the superficial digital flexor tendon (ie, superior check ligament desmotomy [SCLD]). Methods: Retrospective case series. Methods: 332 Thoroughbred racehorses with SDFT consecutively treated by means of SCLD. Methods: Medical records and racing records were reviewed to assess return to racing, number of races completed, time to first race, and life...
Operative factors associated with short-term outcome in horses with large colon volvulus: 47 cases from 2006 to 2013.
Equine veterinary journal    May 29, 2014   Volume 47, Issue 3 279-284 doi: 10.1111/evj.12273
Gonzalez LM, Fogle CA, Baker WT, Hughes FE, Law JM, Motsinger-Reif AA, Blikslager AT.There is an important need for objective parameters that accurately predict the outcome of horses with large colon volvulus. Objective: To evaluate the predictive value of a series of histomorphometric parameters on short-term outcome, as well as the impact of colonic resection on horses with large colon volvulus. Methods: Retrospective cohort study. Methods: Adult horses admitted to the Equine and Farm Animal Veterinary Center at North Carolina State University, Peterson and Smith and Chino Valley Equine Hospitals between 2006 and 2013 that underwent an exploratory coeliotomy, diagnosed with ...
Surgical stress influences cytokine content in autologous conditioned serum.
Equine veterinary journal    May 26, 2014   Volume 47, Issue 2 212-217 doi: 10.1111/evj.12277
Fjordbakk CT, Johansen GM, Løvås AC, Oppegård KL, Storset AK.No recommendations have been made regarding the relative timing of blood collection for autologous conditioned serum (ACS) preparation and surgical procedures. Objective: 1) To identify effects of surgical stress on cytokine levels in ACS, 2) identify haematological markers for prediction of cytokine production in ACS and 3) investigate the necessity for specialised ACS containers when preparing a cytokine-rich serum. Methods: Experimental in vitro study. Methods: Blood was drawn from 15 stallions admitted for elective castration preoperatively and 22-24 h post operatively and incubated in A...
Preliminary investigation of the treatment of equine medial femoral condylar subchondral cystic lesions with a transcondylar screw.
Veterinary surgery : VS    May 16, 2014   Volume 44, Issue 3 281-288 doi: 10.1111/j.1532-950X.2014.12199.x
Santschi EM, Williams JM, Morgan JW, Johnson CR, Bertone AL, Juzwiak JS.To determine if medial femoral condylar (MFC) subchondral cystic lesions (SCL) causing lameness will demonstrate radiographic evidence of healing and lameness reduction after placement of a transcondylar screw in lag fashion. Methods: Retrospective case series. Methods: Horses (n = 20) with lameness attributed to a MFC SCL. Methods: A 4.5 mm screw was inserted in lag fashion across MFC SCL in horses with hindlimb lameness. Post-operative radiography and lameness examinations were performed at 30-60 day intervals after surgery for 120 days, and SCL radiographic area and lameness were graded. Tr...
Impact of tetrodotoxin application and lidocaine supplementation on equine jejunal smooth muscle contractility and activity of the enteric nervous system in vitro.
Veterinary journal (London, England : 1997)    May 15, 2014   Volume 201, Issue 3 423-426 doi: 10.1016/j.tvjl.2014.05.014
Tappenbeck K, Hoppe S, Geburek F, Feige K, Huber K.By blocking the enteric nervous system (ENS) using tetrodotoxin (TTX), previous studies have documented the contractility-enhancing (CE) effects of lidocaine in equine intestinal smooth muscle (SM) at the level of SM cells and/or interstitial cells of Cajal (ICC). The present study examined the impact of ENS deactivation on CE lidocaine effects, and investigated the effects of lidocaine on ENS activity. TTX application did not affect the CE effects of lidocaine, indicating that these were not mediated by TTX-sensitive sodium channels. Application of TTX or ≥100 mg/L lidocaine reduced ENS a...
Outcome of palmar/plantar digital neurectomy in horses with foot pain evaluated with magnetic resonance imaging: 50 cases (2005-2011).
Equine veterinary journal    May 14, 2014   Volume 47, Issue 2 160-164 doi: 10.1111/evj.12262
Gutierrez-Nibeyro SD, Werpy NM, White NA, Mitchell MA, Edwards RB, Mitchell RD, Gold SJ, Allen AK.There is limited knowledge of the foot lesions that influence the outcome of palmar/plantar digital neurectomy (PDN). Objective: 1) To report the short- and long-term outcomes of horses that underwent PDN to alleviate chronic foot pain due to lesions diagnosed by magnetic resonance imaging (MRI) and 2) factors that may influence the outcome of PDN. Methods: Multicentre retrospective study. Methods: Medical records of 50 horses subjected to PDN due to chronic foot pain were reviewed. Age, breed, sex, athletic activity, duration of lameness, affected limb(s), response to anaesthesia of the palma...
Use of a motorized morcellator for elective bilateral laparoscopic ovariectomy in standing equids: 30 cases (2007-2013).
Journal of the American Veterinary Medical Association    May 3, 2014   Volume 244, Issue 10 1191-1197 doi: 10.2460/javma.244.10.1191
Lund CM, Ragle CA, Lutter JD, Farnsworth KD.To describe the use of a motorized morcellator for elective bilateral laparoscopic ovariectomy in standing equids and to evaluate long-term outcome. Methods: Retrospective case series. Methods: 30 equids (20 horses, 9 mules, and 1 pony). Methods: Medical records of equids undergoing elective bilateral laparoscopic ovariectomy from 2007 to 2013 were evaluated. Cases were selected on the basis of use of a motorized morcellator for ovary extraction. Data collected included age, breed, reason for surgery, surgery date, surgical approach, intraoperative complications, surgery and morcellation times...
Visual outcomes of phacoemulsification cataract surgery in horses: 1990-2013.
Veterinary ophthalmology    April 28, 2014   Volume 17 Suppl 1 117-128 doi: 10.1111/vop.12168
Brooks DE, Plummer CE, Carastro SM, Utter ME.To evaluate the long-term visual outcome of phacoemulsification lens extraction surgery in foals and horses and identify any unique postoperative complications that affect the visual outcome. Methods: This is a retrospective medical records study of phacoemulsification cataract surgery in 95 foals and horses from 1990 to 2013. Results: Cataracts were removed by phacoemulsification from 111 eyes of 95 horses ranging in age from 22 days to 26 years (average 8.0 ± 5.7 years). Forty-four of the 95 animals were foals (46.3%). Sixteen horses or foals had surgery bilaterally. One hundred and two eye...
Current treatment of ascending colon volvulus in horses: a survey of ACVS Diplomates.
Veterinary surgery : VS    April 14, 2014   Volume 44, Issue 3 398-401 doi: 10.1111/j.1532-950X.2014.12195.x
Fiege JK, Hackett ES, Rao S, Gillette SC, Southwood LL.To report the results of a survey of opinions on current treatments and estimated outcomes of ascending colon volvulus in horses. Methods: Web-based survey. Methods: American College of Veterinary Surgeons (ACVS) Diplomates (n = 151) who perform gastrointestinal surgery in horses. Methods: ACVS Diplomates with credentials in the large animal specialty obtained by examination in 2010 or earlier (n = 410) were solicited by e-mail to complete a web-based survey designed to determine ascending colon volvulus treatment preferences and outcomes. Results: Responses were obtained from 162 ACVS Diploma...
Perioperative antimicrobials: should we be concerned about antimicrobial drug use in equine surgical patients?
Equine veterinary journal    April 11, 2014   Volume 46, Issue 3 267-269 doi: 10.1111/evj.12247
Southwood LL.No abstract available
Headshaking in 5 horses after paranasal sinus surgery.
Veterinary surgery : VS    April 5, 2014   Volume 43, Issue 6 678-684 doi: 10.1111/j.1532-950X.2014.12147.x
Gilsenan WF, Getman LM, Parente EJ, Johnson AL.To report headshaking and presumptive trigeminal neuritis as a potential complication after paranasal sinus surgery in horses. Methods: Retrospective case series. Methods: Horses (n = 5) that developed headshaking within 45 days of paranasal sinus surgery. Methods: Medical records (2007-2010) of horses that had been evaluated for headshaking after paranasal sinus surgery were reviewed. Results: Of 5 horses that developed headshaking within 45 days of paranasal sinus surgery, resolution occurred after treatment in 2 horses. One horse was euthanatized because clinical signs associated with h...
Coil embolization of a palatine artery pseudoaneurysm in a gelding.
Veterinary surgery : VS    April 5, 2014   Volume 43, Issue 4 487-494 doi: 10.1111/j.1532-950X.2014.12174.x
McClellan NR, Mudge MC, Scansen BA, Jung SS, Russell D.To describe successful transarterial coil embolization of a palatine artery pseudoaneurysm that extended into the caudal maxillary sinus of a gelding. Methods: Clinical report. Methods: A 24-year-old Morgan gelding with right-sided epistaxis. Methods: The right maxillary sinus was imaged by radiography, computed tomography, and sinoscopy. Angiography was performed to locate the source of bleeding, and transarterial coil embolization of a right palatine artery pseudoaneurysm was performed. Results: There was some mucoid nasal discharge and an intermittent cough postoperatively. No epistaxis was...
Surgical treatment of 4 horses for cryptorchidism caused by failure of regression of the cranial suspensory ligament of the testis.
Veterinary surgery : VS    April 5, 2014   Volume 43, Issue 3 266-270 doi: 10.1111/j.1532-950X.2014.12156.x
Ortved KF, Stewart AW, Fubini SL, Hackett RP.To report surgical management of 4 horses with cryptorchidism caused by failure of regression of the cranial suspensory ligament (CSL). Methods: Retrospective case series. Methods: Cryptorchid horses (n = 4). Methods: Horses with unilateral or bilateral cryptorchidism caused by failure of regression of the CSL were treated by removing the retained testes through a standing laparoscopic approach (2), flank laparotomy (1), or paramedian celiotomy (1). After identification of the retained testis attached to the caudal pole of the kidney by the CSL, the vascular pedicle and ductus deferens were li...
Recovery from desflurane anesthesia in horses with and without post-anesthetic xylazine. Aarnes TK, Bednarski RM, Bertone AL, Hubbell JA, Lerche P.The objective of this study was to compare recovery from desflurane anesthesia in horses with or without post-anesthetic xylazine. Six adult horses were anesthetized on 2 occasions, 14 d apart using a prospective, randomized crossover design. Horses were sedated with xylazine, induced to lateral recumbency with ketamine and diazepam, and anesthesia was maintained with desflurane. One of 2 treatments was administered intravenously at the end of anesthesia: xylazine [0.2 mg/kg body weight (BW)] or an equivalent volume of saline. Recovery parameters were recorded and assessed by 2 blinded observe...
A retrospective study comparing the outcome of horses undergoing small intestinal resection and anastomosis with a single layer (Lembert) or double layer (simple continuous and Cushing) technique.
Veterinary surgery : VS    April 1, 2014   Volume 43, Issue 4 471-478 doi: 10.1111/j.1532-950X.2014.12143.x
Close K, Epstein KL, Sherlock CE.To (1) compare postoperative complications and survival in horses after small intestinal resection and anastomosis using 2 anastomosis techniques (single layer Lembert; double layer simple continuous oversewn with Cushing), and (2) to compare outcome by anastomosis type (jejunoileostomy; jejunojejunostomy). Methods: Retrospective case series. Methods: Horses (n = 53). Methods: Medical records (July 2006-July 2010) of all horses that had small intestinal resection and anastomosis. Horses were divided into groups based on technique and type of anastomosis. Comparisons of pre- and intraoperative ...
Ultrasound assisted arthroscopic approach for removal of basilar sesamoid fragments of the proximal sesamoid bones in horses.
Veterinary surgery : VS    April 1, 2014   Volume 43, Issue 6 712-714 doi: 10.1111/j.1532-950X.2014.12180.x
Barrett EJ, Rodgerson DH.To describe an ultrasound assisted arthroscopic approach for removal of non-articular basilar sesamoid fragments in Thoroughbred yearlings. Methods: Thoroughbred yearlings (n = 7). Methods: Basilar sesamoid fragments identified during pre-sale radiographic examination were removed using a palmar/plantar arthroscopic approach to the fetlock joint and ultrasonographic guidance. Complete fragment removal was confirmed by ultrasonography and radiography. Results: Basilar sesamoid fracture fragments were localized and removed successfully using rongeurs and a radiofrequency probe for soft tissu...
Evaluation of the effect of onlay mesenteric flaps on end-to-end jejunojejunostomy healing in horses.
Veterinary surgery : VS    April 1, 2014   Volume 43, Issue 4 479-486 doi: 10.1111/j.1532-950X.2014.12120.x
Aristizabal FA, Lopes MA, Silva A, Avanza MF, Nieto JE.To evaluate the effect of onlay mesenteric flaps (MFs) with end-to-end jejunojejunostomy on stomal diameter, length of jejunum with reduced stomal diameter, abdominal adhesion formation, and healing. Methods: Experimental study. Methods: Healthy adult horses (n = 6). Methods: Two hand sewn end-to-end jejunal anastomoses using a 1 layer simple continuous serosubmucosal suture pattern were performed in each horse ∼ 2 and 5 m oral to the ileocecal fold. Using a random design for selection anastomosis location (oral or aboral), 1 anastomosis was covered with 2 adjacent onlay MFs secured with int...
Effects of experimental mechanical manipulations on local inflammation in the jejunum of horses.
American journal of veterinary research    March 29, 2014   Volume 75, Issue 4 385-391 doi: 10.2460/ajvr.75.4.385
Hopster-Iversen CC, Hopster K, Staszyk C, Rohn K, Freeman DE, Rötting AK.To determine characteristics of the inflammatory reaction in the jejunum of horses in response to various mechanical manipulations. Methods: 12 adult warm blood horses without gastrointestinal tract disorders. Methods: The proximal aspect of the jejunum in each horse was divided into 5 segments, and the following manipulations were performed: manual emptying, placement of Doyen forceps, enterotomy alone, enterotomy with mucosal abrasion, and serosal abrasion. Jejunum samples were collected before (control), immediately after, and 30 minutes after the end of manipulations and histologically eva...
Lidocaine effect on flotillin-2 distribution in detergent-resistant membranes of equine jejunal smooth muscle in vitro.
Veterinary journal (London, England : 1997)    March 26, 2014   Volume 200, Issue 2 325-327 doi: 10.1016/j.tvjl.2014.03.002
Tappenbeck K, Schmidt S, Feige K, Naim HY, Huber K.Lidocaine is the most commonly chosen prokinetic for treating postoperative ileus in horses, a motility disorder associated with ischaemia-reperfusion injury of intestinal tissues. Despite the frequent use of lidocaine, the mechanism underlying its prokinetic effects is still unclear. Previous studies suggested that lidocaine altered cell membrane characteristics of smooth muscle cells. Therefore, the present study aimed to elucidate effects of lidocaine administration on characteristics of detergent-resistant membranes in equine jejunal smooth muscle. Lidocaine administration caused significa...
Development of the Horse Grimace Scale (HGS) as a pain assessment tool in horses undergoing routine castration.
PloS one    March 19, 2014   Volume 9, Issue 3 e92281 doi: 10.1371/journal.pone.0092281
Dalla Costa E, Minero M, Lebelt D, Stucke D, Canali E, Leach MC.The assessment of pain is critical for the welfare of horses, in particular when pain is induced by common management procedures such as castration. Existing pain assessment methods have several limitations, which reduce the applicability in everyday life. Assessment of facial expression changes, as a novel means of pain scoring, may offer numerous advantages and overcome some of these limitations. The objective of this study was to develop and validate a standardised pain scale based on facial expressions in horses (Horse Grimace Scale [HGS]). Results: Forty stallions were assigned to one of ...
Complications associated with perineal urethrotomy in 27 equids.
Veterinary surgery : VS    March 11, 2014   Volume 43, Issue 6 691-696 doi: 10.1111/j.1532-950X.2014.12169.x
Kilcoyne I, Dechant JE.To report the clinical findings, incidence of complications, and outcome associated with perineal urethrotomy in equids. Methods: Retrospective case series. Methods: Equids (n = 27). Methods: Medical records (January 2000 to December 2010) of equids that had a perineal urethrotomy were reviewed. Data retrieved and evaluated were breed, age, surgical technique, use of general anesthesia, complications, time from surgery to development of complications and their management, and outcome. Results: Perineal urethrotomy was performed for urolithiasis (n = 22), for treatment of urethral rents...
A pharmacokinetic/clinical approach to postulate a local action of intra-articular xylazine administration in the horse: a preliminary study.
Journal of veterinary pharmacology and therapeutics    March 8, 2014   Volume 37, Issue 5 464-471 doi: 10.1111/jvp.12110
Di Salvo A, Della Rocca G, Bazzica C, Giontella A, Cagnardi P, Nannarone S.The study aims to evaluate whether the analgesic effect of intra-articular (IA) route of xylazine administered to horses following arthroscopic surgery is due to a local or a systemic action. Two connected studies were performed. In the first, 1 mg/kg b.w. of xylazine was injected IA, and blood samples were taken to assess drug systemic absorption. In addition, systemic effects of the drug (sedation, ataxia or reduction of respiratory and cardiac rate) were registered. Control horses injected with saline IA were included in the study to exclude the influence of anaesthesia in the occurrence o...
Management and long-term outcome of partial glossectomy in 2 horses.
The Canadian veterinary journal = La revue veterinaire canadienne    March 4, 2014   Volume 55, Issue 3 263-267 
Lang HM, Panizzi L, Smyth TT, Plaxton AE, Lohmann KL, Barber SM.Records were reviewed for 2 horses with partial glossectomy, 1 traumatic and 1 elective. According to long-term follow-up by telephone, both horses had recovered well, experiencing only temporary difficulty while eating, and went on to be ridden successfully using mouth bits. Partial glossectomy, therefore, had a favorable prognosis in 2 performance horses. Les dossiers ont été examinés pour 2 chevaux ayant subi une glossectomie partielle, 1 étant une glossectomie traumatique et 1 étant une glossectomie non urgente. Selon le suivi à long terme par téléphone, les deux chevaux se sont b...
Analgesic and gastrointestinal effects of epidural morphine in horses after laparoscopic cryptorchidectomy under general anesthesia.
Veterinary anaesthesia and analgesia    February 27, 2014   Volume 41, Issue 4 430-437 doi: 10.1111/vaa.12133
Martin-Flores M, Campoy L, Kinsley MA, Mohammed HO, Gleed RD, Cheetham J.To evaluate the hypothesis that epidural morphine (0.1 mg kg(-1) ) decreases pain in horses after laparoscopic surgery without adversely affecting gastrointestinal (GI) motility. Methods: Randomized clinical trial. Methods: Eighteen horses undergoing laparoscopic cryptorchidectomy under general anesthesia. Methods: Horses were randomly assigned to receive either epidural morphine (0.1 mg kg(-1) ) or no epidural before the start of surgery. Pain behaviors were assessed during the first two post-operative days using a numerical rating scale. Barium-filled spheres were administered through a naso...
Fertility after fetotomy: a clinical study focusing on heavy draft mares.
The Veterinary record    February 25, 2014   Volume 174, Issue 16 407 doi: 10.1136/vr.101751
Raś A, Rapacz-Leonard A, Raś-Noryńska M, Barański W.Although fetotomy is recommended for all mares when the fetus is dead and difficult to extract, little has been written about fetotomy and heavy draft mares. This lack includes indications for fetotomy in heavy draft mares, differences in treatment and prognosis of heavy mares kept by farmers of low socioeconomic status, and how this procedure affects the mare's further fertility. The literature on mares, in general, also differs on the survival rate of mares that undergo fetotomy, the prevalence of postpartum complications, and further fertility. To answer these questions, we reviewed the me...
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