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Topic:Post-Operative Period

The post-operative period in horses refers to the timeframe following surgical procedures during which the animal undergoes recovery and rehabilitation. This period involves careful monitoring and management to ensure proper healing and to minimize complications. Key aspects of the post-operative period include pain management, wound care, and the prevention of infections. Horses may require restricted movement, dietary adjustments, and regular veterinary evaluations to assess recovery progress. This page compiles peer-reviewed research studies and scholarly articles that explore the management strategies, physiological responses, and outcomes associated with the post-operative period in equine patients.
A technique for laser-facilitated equine pastern arthrodesis using parallel screws inserted in lag fashion.
Veterinary surgery : VS    March 10, 2010   Volume 39, Issue 2 244-253 doi: 10.1111/j.1532-950X.2009.00627.x
Watts AE, Fortier LA, Nixon AJ, Ducharme NG.To report a technique for laser-facilitated, minimally invasive proximal interphalangeal joint (PIJ) arthrodesis in horses. Methods: Case series. Methods: Horses (n=6); 5 thoracic and 2 pelvic limb PIJ. Methods: PIJ osteoarthritis (OA) diagnosis was confirmed by radiography. A diode laser was used to apply 2000 J of energy to the joint followed by insertion of 3 parallel 5.5 mm screws in lag fashion through stab incisions to achieve PIJ arthrodesis. After anesthetic recovery, limbs were maintained in bandages (n=2) or bandage casts (5) for 3 weeks. Horses were allowed exercise or turnout by 3 ...
Long-term outcome after arthroscopic debridement of distal phalanx extensor process fragmentation in 13 horses.
Veterinary surgery : VS    March 10, 2010   Volume 39, Issue 1 107-114 doi: 10.1111/j.1532-950X.2009.00608.x
Crowe OM, Hepburn RJ, Kold SE, Smith RK.To report long-term outcome after arthroscopic removal of fragmentation of the extensor process of the distal phalanx in horses. Methods: Case series. Methods: Adult horses (n=13). Methods: Medical records (2003-2004) of horses that had arthroscopic debridement of fragmentation of the extensor process of the distal phalanx were reviewed. Inclusion criteria included: lameness localized to the foot, fragmentation of the extensor process of the distal phalanx debrided arthroscopically, and a follow-up period of > or = 4 years. Results: Of the 13 horses, lameness was resolved in 11 (85%) initia...
Modified tenoscopic method for carpal flexor retinaculum release in a horse.
Veterinary surgery : VS    March 10, 2010   Volume 39, Issue 2 239-243 doi: 10.1111/j.1532-950X.2009.00631.x
Byron CR, Benson BM, Karlin WM, Stewart AA.To report the use of a proximolateral endoscopic portal with a distolateral instrument portal for carpal retinaculum release in a horse clinically affected with carpal canal syndrome. Methods: Clinical report. Methods: A 4-year-old Thoroughbred female. Methods: Carpal canal syndrome secondary to traumatic suppurative tenosynovitis was treated by accessory carpal bone debridement and carpal retinaculum release using a tenoscopic approach to the carpal flexor synovial sheath through a proximolateral endoscope portal and a distolateral instrument portal. Results: Resolution of carpal sheath effus...
Mastocytoma in the common carpal sheath of the digital flexor tendons of a horse.
Australian veterinary journal    February 13, 2010   Volume 88, Issue 1-2 20-24 doi: 10.1111/j.1751-0813.2009.00534.x
Leadbeater JC, Gutierrez-Nibeyro SD, Brown JA.A 13-year-old Morgan gelding was examined for right forelimb lameness and tenosynovitis of the right common carpal sheath of the digital flexor tendons. The horse had moderate right forelimb lameness at the trot and marked effusion of the right common carpal sheath of the digital flexor tendons. Ultrasonographic examination revealed a soft tissue mass within the proximal pouch of the affected tendon sheath, located adjacent to the distal physis of the radius. Cytology and culture of the fluid revealed a sterile, eosinophilic tenosynovitis. Tenoscopic exploration confirmed the presence of a cap...
Are horses that undergo an exploratory laparotomy for correction of a right dorsal displacement of the large colon predisposed to post operative colic, compared to other forms of large colon displacement?
Equine veterinary journal    February 4, 2010   Volume 42, Issue 1 44-46 doi: 10.2746/042516409X464122
Smith LJ, Mair TS.It is a clinical impression that horses diagnosed with a right dorsal displacement (RDD) of the large colon, are more likely to suffer from recurrent episodes of colic post operatively, compared to other forms of nonstrangulating large colon displacement. Objective: To investigate whether the type of nonstrangulating large colon displacement identified at exploratory laparotomy would influence long-term outcome. Objective: Horses identified with a RDD of the large colon at exploratory laparotomy would be more likely to experience recurrent episodes of post operative colic than other types of d...
In vitro effects of lidocaine on the contractility of equine jejunal smooth muscle challenged by ischaemia-reperfusion injury.
Equine veterinary journal    February 4, 2010   Volume 42, Issue 1 53-58 doi: 10.2746/042516409X475454
Guschlbauer M, Hoppe S, Geburek F, Feige K, Huber K.Post operative ileus (POI) in horses is a severe complication after colic surgery. A commonly used prokinetic drug is lidocaine, which has been shown to have stimulatory effects on intestinal motility. The cellular mechanisms through which lidocaine affects smooth muscle activity are not yet known. Objective: To examine the effects of lidocaine on smooth muscle in vitro and identify mechanisms by which it may affect the contractility of intestinal smooth muscle. Objective: Ischaemia and reperfusion associated with intestinal strangulation can cause smooth muscle injury. Consequently, muscle ce...
Use of ultrasound to evaluate outcome following colic surgery for equine large colon volvulus.
Equine veterinary journal    February 4, 2010   Volume 42, Issue 1 47-52 doi: 10.2746/042516409X456040
Sheats MK, Cook VL, Jones SL, Blikslager AT, Pease AP.The post operative response of the large colon wall after a surgically corrected large colon volvulus (LCV) has not been investigated. Objective: To use transabdominal ultrasound to monitor the post operative change in large colon wall thickness following surgical correction of LCV. Objective: A prolonged period to colon wall involution is correlated with an increased rate of post operative morbidity and mortality. Methods: A prospective clinical study including horses that presented to the North Carolina State University Veterinary Teaching Hospital for colic between September 2006 and March,...
Intrinsic innervation of the ileocaecal junction in the horse: preliminary study.
Equine veterinary journal    January 26, 2010   Volume 41, Issue 8 759-764 doi: 10.2746/042516409x407594
Chiocchetti R, Bombardi C, Mongardi Fantaguzzi C, Russo D, Venturelli E, Montoneri C, Spadari A, Romagnoli N, Grandis A.In horses, morpho-functional studies related to the enteric nervous system (ENS) controlling the sphincters are lacking. Objective: To investigate immunohistochemically the morphology, distribution, density, phenotypes and projections of neurons controlling the ileocaecal junction (ICJ). Methods: Two young horses were anaesthetised and underwent midline laparotomy. The neuronal retrograde fluorescent tracer Fast Blue (FB) was injected into the wall of the ICJ. A post surgical survival time of 30 days was used. Following euthanasia, the ileum and a small portion of caecum were removed. Cryosect...
Surgical thrombectomy in horses with aortoiliac thrombosis: 17 cases.
Equine veterinary journal    January 26, 2010   Volume 41, Issue 8 754-758 doi: 10.2746/042516409x422939
Rijkenhuizen AB, Sinclair D, Jahn W.Aortoiliac thrombosis (AIT) is a progressive vascular disease characterised by an exercise-induced hindlimb lameness. After developing a surgical technique, a follow-up study was required. Objective: To assess the surgical results of a surgical thrombectomy in horses with AIT, a chronic arterial occlusive disease of the aorta and its caudal arteries. Methods: Seventeen cases showed the typical signs of AIT and diagnosis was confirmed by Doppler-ultrasonography. Average age of the horses was 12 years. Seven stallions, 6 mares and 4 geldings were included. Results: The thrombus was located in th...
Effect of ventriculectomy versus ventriculocordectomy on upper airway noise in draught horses with recurrent laryngeal neuropathy.
Equine veterinary journal    January 26, 2010   Volume 41, Issue 8 729-734 doi: 10.2746/042516409x434099
Cramp P, Derksen FJ, Stick JA, Nickels FA, Brown KE, Robinson P, Robinson NE.Little is known about the efficacy of bilateral ventriculectomy (VE) or bilateral ventriculocordectomy (VCE) in draught horses. Objective: To compare the effect of VE and VCE on upper airway noise in draught horses with recurrent laryngeal neuropathy (RLN) by use of quantitative sound analysis techniques. Objective: In competitive draught horses with grade 4 RLN, VE and VCE reduce upper airway noise during exercise, but VCE is more effective. Methods: Thirty competitive hitch or pulling draught horses with grade 4 RLN were evaluated for upper airway sound during exercise. Respiratory rate (RR)...
Inflammatory reaction to implanted equine pericardium xenograft.
The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons    December 21, 2009   Volume 49, Issue 2 155-158 doi: 10.1053/j.jfas.2009.10.003
DeCarbo WT, Feldner BM, Hyer CF.Equine pericardium xenograft is now widely used to augment Achilles tendon repair. In this article, we describe the case of a postoperative complication in a healthy 37-year-old male who underwent primary repair, augmented with equine pericardium, of his acutely ruptured Achilles tendon. At 4 months postoperative, an indurated and fluctuant subcutaneous soft tissue reaction was noted at the repair site. Further questioning led the patient to recall having an allergy to horses, although it had been a very long time since he had experienced any symptoms related to the allergy and, as such, he fa...
Plasma arginine vasopressin concentration in horses undergoing surgery for colic.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)    December 19, 2009   Volume 19, Issue 6 528-535 doi: 10.1111/j.1476-4431.2009.00475.x
Ludders JW, Palos HM, Erb HN, Lamb SV, Vincent SE, Gleed RD.To determine if horses before undergoing anesthesia for surgical correction of colic would have lower plasma arginine vasopressin (AVP) concentrations than healthy horses undergoing anesthesia for arthroscopic surgery, and would not increase their plasma AVP concentrations in response to anesthesia and surgery. Methods: Prospective clinical study. Methods: University teaching hospital. Methods: Fourteen horses with colic and 8 healthy horses. Methods: Horses with colic underwent anesthesia and surgery for alleviation of colic, and healthy horses underwent anesthesia and surgery for arthroscopy...
Treatment of carpometacarpal osteoarthritis by arthrodesis in 12 horses.
Veterinary surgery : VS    December 19, 2009   Volume 38, Issue 8 1006-1011 doi: 10.1111/j.1532-950X.2009.00590.x
Barber SM, Panizzi L, Lang HM.To evaluate arthrodesis as a treatment for carpometacarpal joint osteoarthritis (CMC-OA). Methods: Case series. Methods: Horses (n=12) with CMC-OA. Methods: Arthrodesis was facilitated by insertion and fanning of a drill bit into the CMC joint at several (3-5) locations in 15 limbs. Follow-up radiographs were obtained for 7 horses (9 limbs). Outcome was determined by telephone survey of owners based on postoperative pain, return to use, appearance of the limb, and success of treatment. Results: Postoperative pain was slight or moderate in 10 of 12 (83%) horses during the first 30 days, and 11 ...
Postoperative race performance is not correlated with degree of surgical abduction after laryngoplasty in National Hunt Thoroughbred racehorses.
Veterinary surgery : VS    December 19, 2009   Volume 38, Issue 8 934-940 doi: 10.1111/j.1532-950X.2009.00605.x
Barakzai SZ, Boden LA, Dixon PM.To (1) assess the degree of arytenoid cartilage abduction lost after laryngoplasty (LP) in Thoroughbred National Hunt racehorses and (2) to correlate postoperative racing performance with degree of arytenoid abduction after LP. Methods: Case series. Methods: National Hunt Thoroughbred racehorses (n=68). Methods: Grade of postoperative arytenoid abduction for National Hunt racehorses that had LP with ventriculocordectomy was assessed at 1 day, 6 days, and 6 weeks after LP. Race records were analyzed to ascertain if there was correlation between the degree of arytenoid cartilage abduction and va...
Race performance after laryngoplasty and ventriculocordectomy in National Hunt racehorses.
Veterinary surgery : VS    December 19, 2009   Volume 38, Issue 8 941-945 doi: 10.1111/j.1532-950X.2009.00600.x
Barakzai SZ, Boden LA, Dixon PM.To evaluate the effect of laryngoplasty (LP) on race performance in longer distance (National Hunt) Thoroughbred racehorses. Methods: Case-control study. Methods: National Hunt Thoroughbred racehorses (n=71) and race-matched controls (n=126). Methods: Race records for National Hunt racehorses that had LP and ventriculocordectomy were analyzed and racing performance was compared with race-matched controls. Results: Sixty-three of 71 cases were matched with controls. Postoperatively, 78% of cases raced, 47% improved their individual performance and cases were as likely to start in 1 or 3 races a...
The bispectral index during recovery from halothane and sevoflurane anaesthesia in horses.
Veterinary anaesthesia and analgesia    December 19, 2009   Volume 37, Issue 1 25-34 doi: 10.1111/j.1467-2995.2009.00507.x
Belda E, Blissitt KJ, Duncan JC, Laredo FG, Escobar Gil de Montes M, Clutton RE.To record the bispectral index (BIS) when horses moved during either halothane or sevoflurane anaesthesia and when they made volitional movements during recovery from these anaesthetics. Methods: Randomized prospective clinical study. Methods: Twenty-five client-owned horses undergoing surgery aged 8.8 (+/- 5.3; 1-19) years (mean +/- SD; range). Methods: Baseline BIS values were recorded before pre-anaesthetic medication (BIS(B)) and during anaesthesia (BIS(A)) maintained with halothane (group H; n = 12) or sevoflurane (group S; n =13) at approximately 0.8-0.9 x minimum alveolar concentrations...
Use of propofol-xylazine and the Anderson Sling Suspension System for recovery of horses from desflurane anesthesia.
Veterinary surgery : VS    December 19, 2009   Volume 38, Issue 8 927-933 doi: 10.1111/j.1532-950X.2009.00599.x
Steffey EP, Brosnan RJ, Galuppo LD, Mama KR, Imai A, Maxwell LK, Cole CA, Stanley SD.To characterize the behavior of horses recovering in the Anderson Sling Suspension System after 4 hours of desflurane anesthesia and postdesflurane intravenous (IV) administration of propofol and xylazine. Methods: Experimental study. Methods: Healthy horses (n=6), mean+/-SEM age 12.3+/-1.8 years; mean weight 556+/-27 kg. Methods: Each horse was anesthetized with xylazine, diazepam, and ketamine IV and anesthesia was maintained with desflurane in O(2). At the end of 4 hours of desflurane, each horse was positioned in the sling suspension system and administered propofol-xylazine IV. Recovery e...
Lameness and effusion of the tarsocrural joints after arthroscopy of osteochondritis dissecans in horses.
The Veterinary record    December 17, 2009   Volume 165, Issue 24 709-712 
Brink P, Dolvik NI, Tverdal A.The presence and degree of tarsocrural joint effusion and lameness, and the result of a hindlimb flexion test were scored subjectively in 79 horses before, and six weeks to 20 months after, arthroscopic surgery to remove osteochondritis dissecans fragments. The scores of all three variables improved significantly after surgery. The score reductions for the right and left hindlimbs, respectively, were 82 per cent and 95 per cent for lameness, 48 per cent and 41 per cent for joint effusion, and 89 per cent and 84 per cent for reaction to flexion (P < or = 0.01). The oldest horses reacted more...
Long-term prognosis of gastrojejunostomy in foals with gastric outflow obstruction: 16 cases (2001-2006).
Equine veterinary journal    November 26, 2009   Volume 41, Issue 7 653-657 doi: 10.2746/042516409x424126
Coleman MC, Slovis NM, Hunt RJ.It has been suggested that the success of gastric bypass surgery in foals for the treatment of gastric outflow obstruction is poor. However, few reports exist evaluating the long-term prognosis of these cases. Objective: To determine the long-term success of foals, including racing records, surgically treated for gastric outflow obstruction secondary to gastroduodenal ulceration. Methods: Medical records of foals undergoing surgical treatment of gastric outflow obstruction secondary to gastroduodenal ulceration were evaluated for clinical information. Owners, trainers and race records were eva...
Surgical repair of an oesophageal stricture and prestenotic dilatation in a horse.
Tijdschrift voor diergeneeskunde    November 17, 2009   Volume 134, Issue 18 740-743 
Voermans M, Skidell J, Winberg F.Prestenotic oesophageal dilatation and stricture were diagnosed in a horse with a history of trauma in the cervical area and recurrent oesophageal obstruction. The diagnosis was established on the basis of the clinical examination, endoscopy, and positive contrast oesophagography. Conservative treatment was unsuccessful and surgical intervention was necessary. Oesophageal myectomy combined with myoplasty was performed, simultaneously relieving the dilatation and the stricture. No abnormalities were detected 8 weeks after surgery. The horse was on a normal diet and oesophageal obstruction did r...
Buccal mucosal urethroplasty for treatment of recurrent hemospermia in a stallion.
Journal of the American Veterinary Medical Association    November 17, 2009   Volume 235, Issue 10 1212-1215 doi: 10.2460/javma.235.10.1212
Hackett ES, Bruemmer J, Hendrickson DA, McCue PM.Description-An 11-year-old Quarter Horse stallion was admitted for intermittent hemospermia of 4 years' duration. Results: A linear vertical defect had been detected endoscopically following multiple episodes of hemospermia on the caudodorsal convex surface of the urethra at the level of the ischial arch. Results: When sexual rest alone did not result in complete healing of the urethral defect, a subischial urethrotomy and buccal mucosal urethroplasty were performed. The surgical site healed without complication. Four months of sexual rest was recommended after surgery. Repeat endoscopy at 4 m...
Analgesic effects of butorphanol tartrate and phenylbutazone administered alone and in combination in young horses undergoing routine castration.
Journal of the American Veterinary Medical Association    November 17, 2009   Volume 235, Issue 10 1194-1203 doi: 10.2460/javma.235.10.1194
Sanz MG, Sellon DC, Cary JA, Hines MT, Farnsworth KD.To compare the analgesic efficacy of administration of butorphanol tartrate, phenylbutazone, or both drugs in combination in colts undergoing routine castration. Methods: Randomized controlled clinical trial. Methods: 36 client-owned colts. Methods: Horses received treatment with butorphanol alone (0.05 mg/kg [0.023 mg/lb], IM, prior to surgery and then q 4 h for 24 hours), phenylbutazone alone (4.4 mg/kg [2.0 mg/lb], IV, prior to surgery and then 2.2 mg/kg [1.0 mg/lb], PO, q 12 h for 3 days), or butorphanol and phenylbutazone at the aforementioned dosages (12 horses/group). For single-drug-tr...
A non-invasive technique for standing surgical repair of urinary bladder rupture in a post-partum mare: a case report.
Irish veterinary journal    November 1, 2009   Volume 62, Issue 11 734-736 doi: 10.1186/2046-0481-62-11-734
Stephen J, Harty M, Hollis A, Yeomans J, Corley K.An 11-year-old mare presented 36 hours after foaling with a ruptured bladder. Uroperitoneum was diagnosed on ultrasound and from the creatinine concentration of the peritoneal fluid. Bladder endoscopy demonstrated tissue necrosis and a rent in the dorsocranial aspect of the bladder. Following stabilisation, including abdominal drainage and lavage, the mare was taken to standing surgery. Under continuous sedation and epidural anaesthesia, and after surgical preparation, a Balfour retractor was placed in the vagina. Using sterile lubricant and moderate force, it was possible to insert a hand int...
Analgesic effect of butorphanol in ponies following castration.
Equine veterinary journal    October 7, 2009   Volume 41, Issue 6 552-556 doi: 10.2746/042516409x391024
Love EJ, Taylor PM, Clark C, Whay HR, Murrell J.In the UK butorphanol has a marketing authorisation for administration to horses for sedation in combination with detomidine, and at a higher dose (0.1 mg/kg bwt), for the alleviation of pain. There is only a limited number of clinical studies designed to examine the analgesic effects of butorphanol administration following surgery. Objective: To investigate the effect of premedication with butorphanol on post operative pain following castration under general anaesthesia in ponies. Objective: Ponies receiving butorphanol would experience less pain after castration than ponies that did not rece...
Results and complications of a novel technique for primary castration with an inguinal approach in horses.
Equine veterinary journal    October 7, 2009   Volume 41, Issue 6 547-551 doi: 10.2746/042516409x415018
Kummer M, Gygax D, Jackson M, Bettschart-Wolfensberger R, Fürst A.Complications associated with equine castration can have medical and financial consequences. This retrospective study investigated a novel method of castration via an inguinal approach in mature stallions and compared the incidence of complications with other methods. Objective: Castration via an inguinal approach has a low complication rate at the site of surgery compared with other castration techniques. Methods: Mature stallions (n = 238) were castrated under general anaesthesia in dorsal recumbency using an inguinal approach. The vaginal process was incised, the spermatic cord ligated twic...
Partial resection of the plica salpingopharyngeus for the treatment of three foals with bilateral tympany of the auditory tube diverticulum (guttural pouch).
Journal of the American Veterinary Medical Association    September 16, 2009   Volume 235, Issue 6 731-733 doi: 10.2460/javma.235.6.731
Sparks HD, Stick JA, Brakenhoff JE, Cramp PA, Spirito MA.3 foals were referred for treatment of tympany of the auditory tube diverticulum (guttural pouch). Results: Bilateral guttural pouch tympany was diagnosed in all 3 foals on the basis of clinical signs and results of radiographic and endoscopic evaluations and gutturocentesis. In each foal, previous medical or surgical interventions or both had failed to correct the problem. Results: Bilateral surgical resection of the plica salpingopharyngeus was performed. Follow-up telephone interviews with owners 8 months to 3 years after surgery revealed that long-term resolution of the tympany had been ac...
Evaluation of low-molecular-weight heparin for the prevention of equine laminitis after colic surgery.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)    August 21, 2009   Volume 19, Issue 1 113-119 doi: 10.1111/j.1476-4431.2008.00379.x
de la Rebière de Pouyade G, Grulke S, Detilleux J, Salciccia A, Verwilghen DR, Caudron I, Gangl M, Serteyn DD.The aim of this study is to describe the prevalence of postoperative laminitis in colic cases and to determine if low-molecular-weight heparin (LMWH) is effective in preventing this complication. Methods: Retrospective clinical study. Methods: Client-owned horses. Interventions- SC administration of enoxaparin during the postoperative period. Results: Medical records of 360 horses undergoing surgery for colic and surviving at least 3 days were evaluated. Fifty-six horses admitted before 1995 did not receive LMWH (control group) and 304 admitted after 1995 received LMWH as a prophylaxis for lam...
A lateral approach to the repair of propagating fractures of the medial condyle of the third metacarpal and metatarsal bone in 18 racehorses.
Veterinary surgery : VS    August 14, 2009   Volume 38, Issue 6 689-695 doi: 10.1111/j.1532-950X.2009.00562.x
Wright IM, Smith MR.To report the technique, observations on fracture configurations and results of treatment by fixation lag screw following the fracture plane determined by an approach to the third metacarpal/metatarsal bone (MC3/MT3) that begins laterally over the metacarpo(metatarso)phalangeal joint and extends dorsally over the diaphysis of the bone. Methods: Case series. Methods: Thoroughbred horses (n=18) with propagating fractures of the medial condyle of MC3/MT3. Methods: Retrospective analysis of case records of horses with fractures of the medial condyle of MC3/MT3 that propagated sagittaly or in a spi...
Acute phase response to surgery of varying intensity in horses: a preliminary study.
Veterinary surgery : VS    August 14, 2009   Volume 38, Issue 6 762-769 doi: 10.1111/j.1532-950X.2009.00564.x
Jacobsen S, Nielsen JV, Kjelgaard-Hansen M, Toelboell T, Fjeldborg J, Halling-Thomsen M, Martinussen T, Thoefner MB.To evaluate the postoperative inflammatory response of horses to elective surgery of varying intensity. Methods: Prospective longitudinal study. Methods: Horses referred to 2 hospitals for either arthroscopic removal of a unilateral osteochondritic lesion in the tibiotarsal joint (minimal surgical trauma, n=11), correction of recurrent laryngeal neuropathy by laryngoplasty and ventriculectomy (intermediate surgical trauma, n=10) or removal of an ovarian tumor by laparotomy (major surgical trauma, n=5). Methods: Horses had a thorough clinical examination every day. White blood cell (WBC) counts...
Effect of firocoxib or flunixin meglumine on recovery of ischemic-injured equine jejunum.
American journal of veterinary research    August 4, 2009   Volume 70, Issue 8 992-1000 doi: 10.2460/ajvr.70.8.992
Cook VL, Meyer CT, Campbell NB, Blikslager AT.To determine whether treatment of horses with firocoxib affects recovery of ischemic-injured jejunum, while providing effective analgesia. Methods: 18 horses. Methods: Horses (n = 6 horses/group) received saline (0.9% NaCl) solution (1 mL/50 kg, IV), flunixin meglumine (1.1 mg/kg, IV, q 12 h), or firocoxib (0.09 mg/kg, IV, q 24 h) before 2 hours of jejunal ischemia. Horses were monitored via pain scores and received butorphanol for analgesia. After 18 hours, ischemic-injured and control mucosa were placed in Ussing chambers for measurement of transepithelial resistance and permeability to lipo...
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