Recurrence in horses refers to the reappearance of a disease, condition, or clinical sign after a period of remission or recovery. This phenomenon can occur in various equine diseases and conditions, including laminitis, colic, and respiratory infections. Recurrence may be influenced by factors such as genetics, management practices, environmental conditions, and the nature of the initial disease. Understanding the patterns and causes of recurrence is important for developing effective prevention and management strategies. This page compiles peer-reviewed research studies and scholarly articles that investigate the mechanisms, risk factors, and implications of recurrence in equine health.
Kisthardt KK, Schumacher J, Finn-Bodner ST, Carson-Dunkerley S, Williams MA.Case records of 7 horses diagnosed with pyelonephritis were reviewed to determine common features that might aid in diagnosis, treatment, and prognosis of this disease. All 7 horses had been admitted for evaluation of hematuria. During cystoscopy of 5 horses, hemorrhage was observed from one or both ureters. Renal biopsy of 1 horse, laboratory analysis of ureteral discharge of 2 horses, and renal ultrasonography of all horses indicated that pyelonephritis was the cause of hemorrhage. Sonographic renal changes included decreased length, increased echogenicity, abnormal outline, loss of corticom...
McCauley CT, Hawkins JF, Adams SB, Fessler JF.To determine outcome of horses in which cutaneous masses were removed with a carbon dioxide laser. Methods: Retrospective study. Methods: 32 horses. Methods: Medical records of horses with 1 or more cutaneous masses treated with a carbon dioxide laser were examined. Follow-up information was obtained through telephone interviews with owners and referring veterinarians. Results: Cutaneous masses were classified as sarcoids (15 horses), neoplastic masses other than sarcoids (squamous cell carcinoma [91; fibroma [1]; and melanoma [1]), and nonneoplastic masses (6). Minimum follow-up time was 6 mo...
Martens A, De Moor A, Vlaminck L, Pille F, Steenhaut M.Ninety-five horses with sarcoids were subjected to three types of treatment: surgical excision (conventional or carbon dioxide laser), cryotherapy or local BCG vaccination. The type of treatment was selected on the basis of the size, location and clinical appearance of the tumours. The choice between conventional and laser excision was empirical. A successful outcome was obtained in 11 of 14 (79 per cent) of the horses treated by cryosurgery, 18 of 27 (67 per cent) treated by BCG vaccination, 18 of 22 (82 per cent) treated by conventional excision, and 20 of 28 (71 per cent) treated with a car...
Martens A, De Moor A, Demeulemeester J, Peelman L.To examine apparently normal skin around equine sarcoids for evidence of bovine papilloma virus (BPV) DNA, and to relate this finding to the observed recurrence after surgery. Methods: Prospective study. Methods: Forty-one equine sarcoids from 19 horses. Methods: The tumors were surgically excised at a measured distance of 8, 12, or 16 mm. Samples from the tumor and of the entire surrounding skin were taken at 4, 8, 12, and 16 mm from the tumor border and analyzed for the presence of BPV DNA using polymerase chain reaction (PCR) amplification. The samples were grouped per examined sarcoid, and...
Knottenbelt DC, Kelly DF.OBJECTIVE: Diagnosis and management of periorbital sarcoids in horses is a significant clinical challenge for the practicing veterinary surgeon and pathologist. The purpose of this study was to investigate the response of various types of sarcoids to different therapeutic methods. Animals studied Medical records of 445 clinical patients. Procedures This paper retrospectively examines the clinical and histological features of periorbital sarcoids and the treatment of 445 cases. Treatment by surgical excision, cryosurgery, Bacillus-Calmette-Gaérin (BCG) immunomodulation, topical cytotoxic appli...
Mair TS, Walmsley JP, Phillips TJ.The medical records of 45 horses treated for suspected squamous cell carcinoma of the penis and/or prepuce were reviewed. The age of 40 horses was known, and these had a mean age of 17.4 years. The duration of neoplasia was known for only 3 of the 45 horses. The results of histological evaluation of lesions, available for 35 horses, confirmed that the diseased tissue was squamous cell carcinoma. The location of gross neoplastic lesions was recorded for 43 horses; the glans penis was involved in 24 horses, the body of the penis or the inner lamina of the preputial fold in 27 horses, and the ext...
Kinnunen RE, Tallberg T, Stenbäck H, Sarna S.Twenty-one horses with sarcoid tumours were treated by bio-immunotherapy using autogenous vaccines during 1991-1997. At operation the base of the tumour was left in the skin and autovaccines were made from extirpated tumour tissue by polymerization. The horses thus formed their own internal control group. One of 12 horses having a primary tumour, and four of 9 horses suffering recurrent tumours, prior to bio-immunotherapy, developed single recurrences. Four of these five horses suffering recurrence were treated anew, leading to remission. Disease-free intervals were longer for primary (P = 0.0...
Dabareiner RM, White NA.A 9-year-old Thoroughbred was evaluated for clinical signs of acute abdominal pain. During laparotomy, a rent in the diaphragm and herniation of the small intestine into the thoracic cavity were detected. Because edges of the rent were smooth and fibrous, which suggested the defect was chronic, the abdomen was closed without repairing the rent. After recurrence of clinical signs, a second laparotomy was performed, during which the intestines were found to have reherniated. The diaphragmatic rent was repaired, using a polypropylene mesh secured with stainless steel staples. The horse recovered ...
Rothaug PG, Tulleners EP.To describe a technique of contact neodymium:yttrium-aluminum-garnet (Nd:YAG) laser-assisted excision of progressive ethmoid hematoma (PEH) in horses, to determine the recurrence rate of clinical signs of PEH in horses with follow-up time of a minimum of 12 months, and to compare this result with reported results achieved by using conventional techniques. Methods: Retrospective study. Methods: 21 horses with 26 PEH. Methods: Medical records of all horses with PEH treated by Nd:YAG laser excision from December 1986 through August 1996 were analyzed. Twenty-one horses underwent unilateral (18 su...
Carstanjen B, Jordan P, Lepage OM.The objective of this retrospective clinical study was to evaluate the carbon dioxide laser in the treatment of single and multiple sarcoids in 60 animals (44 horses, 13 donkeys, 2 mules, and 1 pony). Only animals that had been operated on 6 mo or more ago were included. Recurrence, new manifestation rate, and cosmetic outcome were determined. Recurrence was observed in 23 (38%) individuals. Animals with new sarcoid manifestation with or without recurrence of a sarcoid were observed in 35 cases (58%). Cases of scar tissue formation and, rarely, leukotrichia were observed. Animals presented wit...
Singh SP, Besner GE, Schauer GM.This report describes the clinical and histologic features of a pulmonary tumor in a 14-year-old girl that is most consistent with a rare entity described in the literature as "pulmonary endodermal tumor resembling fetal lung" (PET). This tumor is composed of glycogen-rich columnar cells forming complex glands with focal festooning and mitotic activity, admixed with solid "morules" of cells with eosinophilic cytoplasm and focal nuclear clearing. Patchy tumor necrosis and a bland stroma were also present. Immunoreactivity for carcinoembryonic antigen (CEA), alpha 1-antichymotrypsin, and 12E7 wa...
Sedrish SA, Moore RM, Valdes-Vasquez MA, Haynes PF, Vicek T.Pythiosis, caused by Pythium insidiosum, is a common cutaneous granulomatous disease in horses. Surgical removal is the most common treatment; however, high rates of recurrence have been reported. Results of examination of 2 horses with pythiosis granulomas in which a neodymium:yttrium-aluminum-garnet laser was used to photoablate the bed after removal are reported. The mass had not recurred in either horse 1 year after surgery. Photoablation results in collateral thermal necrosis and may kill organisms that have infiltrated surrounding tissues, thus reducing the risk of recurrence.
van der Woerdt A, Gilger BC, Wilkie DA.Squamous cell carcinoma involving the cornea and conjunctiva of the left eye in a 14-year-old horse was treated by superficial keratectomy in combination with beta-radiation and radiofrequency hyperthermia. The tumor recurred 4 months later in the central cornea at the edge of the previous keratectomy site. Penetrating keratoplasty was performed in an effort to remove the tumor and retain a visual eye. The eye was visual 13 months after surgery. Mild fibrosis and vascularization were observed in the area of the penetrating keratoplasty.
Zamos DT, Schumacher J, Loy JK.Nasopharyngeal conidiobolomycosis caused by Conidiobolus coronatus was diagnosed in a horse after endoscopic and histopathologic examinations of a biopsy specimen. The fungal lesions in the nasopharynx were substantially reduced in size after intralesional injection of amphotericin B through the biopsy channel of a videoendoscope in combination with i.v. administration of sodium iodide and oral administration of potassium iodide during a 2-month period. Endoscopy performed 15 months after initial examination revealed regression of the granulomatous masses in the nasopharynx and complete disapp...
Broström H.Associations between clinical parameters of sarcoids and the equine leucocyte antigen system (ELA) were analysed for 120 Swedish horses. Median age of affected horses was 5.2 years, and the majority presented with solitary tumors between 2 and 5 cm in diameter and ventral abdomen was a predilection site. Clinical signs first appeared at a median age of 3.5 years, and sarcoids at different locations first appeared at different ages. Lesions at different sites differed in size, and multiple tumors, early onset, long duration, and older age all had an association with large size. Clinical manifes...
Tetens J, Tulleners EP, Ross MW, Orsini PG, Martin BB.Tympany of the auditory tube diverticulum was treated in 2 Standardbred foals by fenestrating the median septum, using an endoscopically placed Nd:YAG laser. Recurrence in 1 foal was treated by enlarging the fenestration, using a modified Whitehouse approach, and the pharyngeal opening of the auditory tube. Use of the Nd:YAG laser eliminates the risk of inadvertent cranial nerve damage associated with incisions into the auditory tube diverticulum. The procedure can be performed with the horse sedated or anesthetized. Clinical signs can recur in the fenestration heals closed or if the condition...
van der Velden MA, Klein WR.During a 3-year period 21 horses were surgically treated because of large abdominal wall defects. In each case the defect was bridged with a polypropylene mesh, which was placed on the outside of the hernial ring. This was in contrast with the technique for mesh herniorrhaphy generally described in human and veterinary literature, in which the mesh is always implanted on the inside of the hernial ring. One horse was destroyed on the first postoperative day because of postanaesthetic myelomalacia. Surgical repair as described was successful in 18 patients. Recurrence of herniation occurred in t...
Bristol DG.Enterocutaneous fistulae are rare in horses and occur most commonly as a complication of umbilical hernias or their treatment. Horses with enterocutaneous fistulae may be successfully treated by en bloc resection of the body wall and intestine or by allowing second intention healing. Complications associated with surgical intervention include fever, colic, incisional problems, and recurrence of the fistula. Nonsurgical management of two horses with presumptive large colon fistulae resulted in resolution of the fistulae without complications.
Marr CM, Love S, Boyd JS, McKellar Q.Ultrasonographic examination was used to define the severity of injuries to the superficial digital flexor tendon in 73 National Hunt or point-to-point racehorses and the factors influencing the outcome of the cases were examined. Thirty-four of the horses (46 per cent) returned to work with an average time out of training of 13.5 months. The rate of recurrence of the injury was 35 per cent. The severity of the lesions was related to the outcome; all the mildly affected horses returned to work, with 63 per cent of them racing and an average time out of training of 10.2 months; 50 per cent of t...
Schwink KL.Uveitis (inflammation of the iris, ciliary body, or choroid) is a potentially blinding condition with a significant economic impact on the horse industry. Variable symptoms are described, as well as a considerable range of structural and functional sequelae. Known causes of initial episodes include bacterial, viral, traumatic, and parasitic insults, with recurrence by immunologic mechanisms. Treatment strategies and management recommendations that may reduce the incidence or severity of episodes are discussed.
Foley JP, Legendre AM.Itraconazole, a tricyclic azole effective against a number of deep mycotic diseases, was used to treat a Quarter Horse filly with coccidioidomycosis. The horse was almost normal after 90 days of treatment. Five months after discontinuing itraconazole treatment, the filly had severe neck pain and neurologic signs from recurrence of coccidioidomycosis and was treated with itraconazole for an additional 6 months. Her clinical condition improved to almost normal and the filly has remained normal for 2 years. There was no evidence of drug toxicity.
Greet TR.This paper describes the outcome of treatment in 23 horses with an ethmoidal haematoma. In 22 cases a diagnosis could be made by endoscopic means alone but in 1 horse the lesion was confined to the maxillary sinus and a diagnosis was made only at surgery. One horse was destroyed at the owner's request but the other 22 underwent radical excision of the lesion via a facial flap approach under general anaesthesia. Post-operative haemorrhage was controlled by nasal packing with a gauze bandage and this was removed between the 2nd and 4th post-operative day. One horse died from encephalitis the day...
Hardy J, Robertson JT, Reed SM.Chronic constrictive pericarditis was diagnosed in a 6-year-old Thoroughbred mare based on the clinical findings of right congestive heart failure, hyperechoic pericardium without pericardial effusion, and a dip-and-plateau shape of the right ventricular pressure curve with equilibration of the diastolic pressures in all cardiac chambers. Treatment was attempted by partial pericardiectomy using a right lateral thoracotomy approach. Because of severe epicardial involvement recurrence of the constrictive pathology was noted 6 weeks after the surgical procedure. However, in selected cases in whic...
Klein WR.Squamous cell carcinomas of the bovine eye and equine sarcoids are briefly reviewed. A single injection of BCG into the tumour results in permanent regression of the lesion in 37 per cent of the cattle, regression followed by recurrence of the tumour in 26 per cent and in progressive growth of the tumour in 37 per cent of the cases. Recurrence may be prevented by repeated injection into the lesion. From 50 to 60 per cent of the cows will remain free from tumours. Equine sarcoids show a complete regression in 70-80 per cent of the cases. Tumours on the limbs show a less satisfactory response (l...
Specht TE, Colahan PT, Nixon AJ, Brown MP, Turner TA, Peyton LC, Schneider RK.Ethmoidal hematoma was diagnosed in 9 horses by results of physical examination, endoscopy, radiography, and histologic examination of tissues. The horses had stertorous breathing (n = 4) or intermittently sanguineous nasal discharge (n = 7). All horses underwent sinusotomy and extirpation of the lesion. At reexamination 15 to 104 months after surgery (mean, 61 months), 3 horses had recurrence of ethmoidal hematoma, and 1 horse had ethmoidal hematoma involving the contralateral ethmoturbinates. One of the horses with recurrence of ethmoidal hematoma also developed a contralateral lesion; both ...
Rebhun WC.Corneal squamous cell carcinomas with surface areas of more than 2.0 cm were diagnosed in 26 eyes of 25 horses. The depth of the lesion into the corneal stroma and involvement of the ocular adnexa were important determinants for surgical treatment. Corneal tumors that extended into adjacent palpebral conjunctiva, eyelid, or orbit were not amenable to complete excision, while those that involved only cornea and bulbar conjunctiva were treated surgically by keratectomy and beta radiation. Initial treatment was keratectomy followed by beta radiation on 24 eyes and enucleation of two eyes. Twenty ...
Palmer SE.A verrucous sarcoid was removed from the ear of a horse, using a carbon dioxide laser. The use of carbon dioxide laser excision and ablation enabled complete removal of tumor cells, with minimal damage to underlying normal cartilage. Cosmetic healing was observed with minimal disfigurement. Recurrence of the tumor was not observed after 11 months.
McCue PM, Freeman DE, Donawick WJ.From 1977 to 1986, guttural pouch tympany was diagnosed in 15 horses--11 fillies and 4 colts. Review of the medical records provided results of physical, microbiologic, radiographic, and endoscopic examinations, treatment protocols, complications, and recovery rate. All affected horses had visible swelling in the parotid gland region, 9 had abnormal respiratory noise, 5 had pneumonia, and 1 had dysphagia. Six horses were treated by median septum fenestration alone, and in 8 horses, this procedure was combined with resection of the mucosal flap at the pharyngeal orifice of the eustachian tube. ...
Gaughan EM, Fubini SL, Dietze A.Over an 8-year period, 14 horses were admitted to the New York State College of Veterinary Medicine for evaluation of fistulous withers. Of the 14 horses, 11 were treated surgically and 3 were not treated. Surgical techniques involved radical excision of the affected soft tissue and spinous processes of affected vertebrae. Recurrence rate was 30%, and these horses required additional surgery to resolve the problem.
Bristol DG.Enterocutaneous fistulae are rare in horses and occur most commonly as a complication of umbilical hernias or their treatment. Horses with enterocutaneous fistulae may be successfully treated by en bloc resection of the body wall and intestine or by allowing second intention healing. Complications associated with surgical intervention include fever, colic, incisional problems, and recurrence of the fistula. Nonsurgical management of two horses with presumptive large colon fistulae resulted in resolution of the fistulae without complications.
Giraldo A, Pinard CL, Plattner BL, Dubois MS.A periocular nodular sarcoid was diagnosed on the right upper eyelid and medial canthus of a 12-year-old Thoroughbred mare. Enucleation was performed and during the procedure the mass was noted to be firmly adhered to the underlying frontal bone. Partial ostectomy of the dorsal orbital rim was performed. Histopathology revealed invasion of the cortical lamellar bone and the bone marrow by neoplastic spindle cells and extension of these cells to multiple surgical margins. Recurrence at the level of the surgical site and its surroundings occurred 3 months after the procedure. The horse was eutha...
McCue PM, Freeman DE, Donawick WJ.From 1977 to 1986, guttural pouch tympany was diagnosed in 15 horses--11 fillies and 4 colts. Review of the medical records provided results of physical, microbiologic, radiographic, and endoscopic examinations, treatment protocols, complications, and recovery rate. All affected horses had visible swelling in the parotid gland region, 9 had abnormal respiratory noise, 5 had pneumonia, and 1 had dysphagia. Six horses were treated by median septum fenestration alone, and in 8 horses, this procedure was combined with resection of the mucosal flap at the pharyngeal orifice of the eustachian tube. ...
Klein WR.Squamous cell carcinomas of the bovine eye and equine sarcoids are briefly reviewed. A single injection of BCG into the tumour results in permanent regression of the lesion in 37 per cent of the cattle, regression followed by recurrence of the tumour in 26 per cent and in progressive growth of the tumour in 37 per cent of the cases. Recurrence may be prevented by repeated injection into the lesion. From 50 to 60 per cent of the cows will remain free from tumours. Equine sarcoids show a complete regression in 70-80 per cent of the cases. Tumours on the limbs show a less satisfactory response (l...
Ross MW, Ford TS, Orsini PG.Seven horses, 2 to 4 years of age, were examined because of moderate-to-severe forelimb lameness, mild effusion of the middle carpal joint (3 horses), and pain on palpation of the origin of the suspensory ligament (4 horses). The lameness was abolished by anesthetic infiltration of the middle carpal joint in six horses. In four of them, a high palmar nerve block also abolished the lameness. A linear radiolucency in the proximal end of the third metacarpal bone (McIII) was interpreted as an incomplete longitudinal fracture. In one horse, distinct intramedullary sclerosis limited to the palmar c...
Greet TR.This paper describes the outcome of treatment in 23 horses with an ethmoidal haematoma. In 22 cases a diagnosis could be made by endoscopic means alone but in 1 horse the lesion was confined to the maxillary sinus and a diagnosis was made only at surgery. One horse was destroyed at the owner's request but the other 22 underwent radical excision of the lesion via a facial flap approach under general anaesthesia. Post-operative haemorrhage was controlled by nasal packing with a gauze bandage and this was removed between the 2nd and 4th post-operative day. One horse died from encephalitis the day...
Curnow B, Rich AF, Ireland J, Correa DC, Dunn J, Jenkins D, Carslake H, Ressel L.Although the equine sarcoid is the most common skin neoplasm in domesticated horses, histopathological characteristics have not previously been evaluated for association with recurrence. The aim of this retrospective cohort study was to investigate clinical and histopathological features of excised equine sarcoids and to evaluate their association with recurrence at the original surgical site and at new sites. Clinical records and excisional biopsies from 106 equine sarcoids from 64 horses referred to Leahurst Equine Hospital, University of Liverpool, between March 2010 and February 2015 were ...
Hart SK, Sullins KE.Results of surgical treatment of sinonasal disease in horses have been reported previously; however, this paper describes the outcome of horses in which a specific post operative treatment protocol was used. Objective: The objectives of the study were to determine: 1) short- and long-term outcome; 2) complications; and 3) recurrence rates of different disease processes, when horses were treated with a specific treatment protocol. Methods: Medical records of horses presented for surgical treatment of sinonasal disease from 1996-2007 were reviewed. Results and duration of surgical exploration we...
Conturba B, Lo Feudo CM, Stucchi L, Stancari G, Olivieri L, Ferrucci F.The aim of the present work was to describe a case of recurrent capillary haemangioma at the coronary border of the left front limb in a 6-month-old thoroughbred filly successfully treated with diode laser ablation and adjunctive laser photocoagulation therapy. Le but de cette étude était de décrire un cas d’hémangione capillaire récidivant du bord coronaire du membre antérieur gauche chez un cheval de race de 6 mois traité avec succès par une ablation au laser diode et traitement adjuvant de photo-coagulation au laser. El objetivo del presente trabajo fue describir un caso de hemang...
Schäfer J, Graubner C, Gerber V, Drögemüller C, Underberg J, Gurtner C, Unger L.This case series describes the clinical course of ocular and non-ocular squamous cell carinoma (SCC) in the Haflinger horse and is intended to raise awareness of the high recurrence rate and tendency to metastasize. Eight Haflingers with histologically confirmed SCC were included, five ocular and three non-ocular, who were presented at the Institut Suisse de Médecine Équine (ISME) Bern between July 2015 and January 2022. The ocular SCC cases were all presented because of an apparent mass, which in most cases was post-treatment recurrence. The occurrence of recurrences was observed between 3 ...
van der Woerdt A, Gilger BC, Wilkie DA.Squamous cell carcinoma involving the cornea and conjunctiva of the left eye in a 14-year-old horse was treated by superficial keratectomy in combination with beta-radiation and radiofrequency hyperthermia. The tumor recurred 4 months later in the central cornea at the edge of the previous keratectomy site. Penetrating keratoplasty was performed in an effort to remove the tumor and retain a visual eye. The eye was visual 13 months after surgery. Mild fibrosis and vascularization were observed in the area of the penetrating keratoplasty.
Riggott JM, Quarmby WB.A surgically excised tumour from the thoracic wall of a hunter mare was diagnosed as a fibrosarcoma on histological examination. Its recurrence necessitated further surgery 6 weeks later. Because of the invasive nature of the lesion a prolonged course of chemotherapy was administered postoperatively. The tumour did not recur a second time.
Markel MD, Meagher DM, Richardson DW.Colopexy of the left ventral colon to the abdominal wall was performed in 4 horses with recurrence of large-colon displacement or volvulus. Horses were discharged between 5 and 27 days after surgery. At follow-up evaluation (mean, 10.5 months; range, 7 to 13 months) of the horses, none had recurrence of signs of abdominal pain, and all had normal body weight. Three horses were exercised regularly; signs of abdominal pain were not observed.
Specht TE, Colahan PT, Nixon AJ, Brown MP, Turner TA, Peyton LC, Schneider RK.Ethmoidal hematoma was diagnosed in 9 horses by results of physical examination, endoscopy, radiography, and histologic examination of tissues. The horses had stertorous breathing (n = 4) or intermittently sanguineous nasal discharge (n = 7). All horses underwent sinusotomy and extirpation of the lesion. At reexamination 15 to 104 months after surgery (mean, 61 months), 3 horses had recurrence of ethmoidal hematoma, and 1 horse had ethmoidal hematoma involving the contralateral ethmoturbinates. One of the horses with recurrence of ethmoidal hematoma also developed a contralateral lesion; both ...
Hollis AR.Squamous cell carcinomas are a very common tumor type in horses, and are found in a variety of dermatologic and non-dermatologic locations. Metastasis is common, even at the first presentation of the disease, and a full staging workup is therefore strongly recommended to direct treatment and assist with prognostication. Wide surgical excision remains the treatment of choice in most cases, but recurrence is common, and adjunctive therapy may be indicated to improve the long-term prognosis.
Foley JP, Legendre AM.Itraconazole, a tricyclic azole effective against a number of deep mycotic diseases, was used to treat a Quarter Horse filly with coccidioidomycosis. The horse was almost normal after 90 days of treatment. Five months after discontinuing itraconazole treatment, the filly had severe neck pain and neurologic signs from recurrence of coccidioidomycosis and was treated with itraconazole for an additional 6 months. Her clinical condition improved to almost normal and the filly has remained normal for 2 years. There was no evidence of drug toxicity.
Andersen C, Tnibar A.Medial patellar ligament splitting (MPLS) has been shown to be a highly effective and minimally invasive treatment for upward fixation of the patella (UFP) in horses. However, long-term follow-up results of this procedure have not previously been reported. Objective: To evaluate the long-term resolution of UFP following MPLS and provide information on complications and recurrence. Methods: Retrospective case series. Methods: Data were collected from horses that underwent MPLS between 1999 and 2013. All cases had a confirmed diagnosis of UFP that had not responded to conservative therapy. Data ...
Fürst A, Kummer M, Lischer C, Bertolla R, Auer J, Geyer H.Fifty-four horses with hoof cracks were referred to the Equine Hospital of the University of Zurich, for treatment. The horses were admitted because of lameness or other symptoms caused by the cracks. Deep or complicated quarter cracks were the most common type of cracks diagnosed. Poor conformation and abnormal hoof shape were the most important causes of hoof crack development, whereas injury to the coronary band was a less frequently encountered cause. Effective treatment of this problem includes corrective shoeing, removing horn from the weight-bearing surface as well as from the crack wit...
Hay AN, Witonsky SG, Lindsay DS, LeRoith T, Zhu J, Kasmark L, Leeth CM. is a ubiquitous parasite in the eastern United States, which is the principal causative agent in the neurologic disorder equine protozoal myeloencephalitis (EPM). While much is known about this protozoa's life cycle in its natural host, the opossum (), little is known of how it acts in the aberrant equine host, which displays a high incidence of exposure with a relatively low rate of morbidity. For this study, we employed the popular interferon gamma knockout mouse model to determine the potential for recrudescence of infection after treatment with the anticoccidial drug diclazuril. Mice wer...
Shi L, Hu J, Jin Z.Strangles is one of the most prevalent horse diseases globally. The infected horses may be asymptomatic and can still carry the infectious pathogen after it recovers, which are named asymptomatic infected horses and long-term subclinical carriers, respectively. Based on these horses, this paper establishes a dynamical model to screen, measure, and model the spread of strangles. The basic reproduction number $ mathcal{R}_0 $ is computed through a next generation matrix method. By constructing Lyapunov functions, we concluded that the disease-free equilibrium is globally asymptotically stable if...
Vlahos TP.Tendinopathy and desmopathy are significant causes of morbidity in horses. To evaluate the use of percutaneous ultrasonic debridement (PUD) as a treatment for chronic tendinopathy and desmopathy in the horse. Eight adult horses with 10 affected limbs presented for lameness, ranging from 60-700 days postinjury. Diagnostic ultrasound identified the following: suspensory branch desmitis ( = 1), suspensory body desmitis ( = 2), Achilles tendinopathy ( = 1), desmitis of the accessory ligament of the deep digital flexor (DDF) tendon ( = 1), DDF tendinopathy ( = 2), and superficial digital flexor ten...
Shan R, Steel CM, Sykes B.The impact of recommended withholding periods (RWPs) for omeprazole on the recurrence of Equine Gastric Ulcer Syndrome (EGUS) is unknown. The study was designed to compare the effect of two RWPs on EGUS recurrence post-omeprazole treatment and to determine if a nutraceutical supplement would reduce EGUS recurrence when administrated during an RWP. The study was a blinded, randomized clinical trial. Part 1: Horses were allocated to an RWP0 or RWP2 and crossed over after 4-weeks. Horses received oral omeprazole once daily, except during the RWPs at the end of the treatment periods. Part 2: Horse...
Karalus W, Subharat S, Orbell G, Vaatstra B, Munday JS.Sarcoids are common mesenchymal neoplasms of horses. Although there are few studies in which sarcoids have been followed over a long period of time, sarcoids are considered locally invasive and have been reported to frequently recur following surgical excision. Currently, no histological features have been identified to predict which sarcoids will recur after excision. The present study comprised 49 sarcoids for which histology sections were available and in which the recurrence status of the case was known. Each sarcoid was excised from a different horse. Overall, 12 of the 49 (24%) sarcoids ...
Thurston CC, Sertich PL, McDonnell SM, Parente EJ.To describe a standing hand-assisted laparoscopic ovariohysterectomy in a mare. Methods: A 15-year-old maiden Oldenburg mare. Unassigned: The mare was presented for evaluation of bucking under saddle and uncharacteristic aggressive behavior. Evaluation of a 24-hour video of the mare in a stall showed behavior consistent with caudal visceral abdominal discomfort. Reproductive evaluation revealed a pyometra secondary to complete transluminal cervical adhesions. The mare was initially managed medically with disruption of the adhesions and uterine lavage, but the adhesions reformed within 6 weeks ...
Munday JS, Lewis MC, Leyland MH.Equine sarcoids are common skin tumors that are thought to be caused by cross-species infection by bovine papillomaviruses (BPV). A 16-year-old horse developed a 1cm diameter mandibular gingival mass opposite the right second premolar tooth (406) and a 2cm diameter mass close to the commissure of the lips on the same side of the mouth. The right cheek was diffusely thickened. Histology of the smaller mass revealed a proliferation of mesenchymal cells covered by hyperplastic epithelium that formed thick rete pegs. BPV2 DNA was amplified from the mass. Although the mass had been incompletely exc...
Menzies-Gow NJ, Shurlock T.Feedstuffs are often recommended to mitigate potential damage from acid associated with equine squamous gastric disease (ESGD). In acidic conditions, pectin alters its structure to one like mucus and binds the stomach mucosa, whilst alfalfa has a strong intrinsic acid buffering capacity. The study aimed to determine whether feeding a commercial beet pulp/alfalfa/oat fibre mix aids ESGD healing and/or prevention of recurrence. Ten adult horses with naturally occurring ESGD were included. All animals were treated with omeprazole as per the attending veterinarian's recommendation and randomly all...
Morén S, Kallberg M, Strom L.Uveitis is common in horses, potentially turning chronic (persistent or recurrent) resulting in impaired vision or blindness. All mainstay therapeutics aims at controlling inflammation, but long-term or lifelong treatment is often needed with possibly severe side effects. Therefore, intravitreal injections with low-dose gentamicin (IVGI) have been used in attempt to give a long-lasting result with potentially less side effects. Objective: To retrospectively assess outcome and long-term complications following one or two low-dose IVGI in Swedish horses with chronic uveitis. Methods: Retrospecti...
Whisenant KD, Foucaud M, Mariën T, Levine D, Richardson DW, Stefanovski D, Scherrer NM, Engiles JB, Ortved K.Chronic foot pain, a common cause of forelimb lameness, can be treated by palmar digital neurectomy (PDN). Complications include neuroma formation and lameness recurrence. In humans, neuroanastomoses are performed to prevent neuroma formation. The aim of the study was to evaluate the outcome of horses undergoing dorsal-to-palmar branch neuroanastomosis following PDN. Methods: Retrospective case series. Methods: Eighty-five horses with PDN and dorsal-to-palmar branch neuroanastomosis. Methods: Medical records for horses undergoing this procedure at two hospitals between 2015 and 2020 were revie...
Vernemmen I, Van Steenkiste G, Decloedt A, Meert H, Walser U, van Loon G.Implantable loop recorders (ILRs) are increasingly used in equine cardiology to detect arrhythmias in the context of collapse, poor performance or monitoring for recurrence of atrial fibrillation (AF). However to date, the ILR has never been reported to be used with a remote monitoring functionality in horses, therefore the arrhythmia is only discovered when a clinician interrogates the ILR using dedicated equipment, which might delay diagnosis and intervention. This case report describes the use of an ILR with remote monitoring functionality in a horse with recurrent AF. The remote monitoring...
