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Topic:Retrospective Study

Retrospective studies in horses involve the analysis of pre-existing data to identify patterns, outcomes, and associations related to health and disease within equine populations. These studies utilize historical records, such as veterinary medical histories, treatment outcomes, and diagnostic results, to explore various aspects of equine health and management. Retrospective studies can provide insights into the prevalence of diseases, the effectiveness of treatments, and risk factors associated with certain conditions. This page aggregates peer-reviewed research studies and scholarly articles that focus on the methodologies, findings, and implications of retrospective analyses in equine veterinary science.
Incisional complications following ventral median coeliotomy in horses. Does suturing of the peritoneum reduce the risk?
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere    November 10, 2016   Volume 45, Issue 1 24-32 doi: 10.15653/TPG-160536
Scharner D, Winter K, Brehm W, Kämpfert M, Gittel C.Despite advances in surgical technique in abdominal surgery, incisional complications are frequently reported following ventral midline laparotomy in horses. The aim of this study was to determine the incidence of incisional complications at our clinic and to identify possible risk factors. Furthermore, we investigated whether suturing the peritoneum leads to a reduction of incisional complications. Methods: In this retrospective study, records of patients of the Large Animal Clinic for Surgery of the University of Leipzig from January 2010 to December 2015 were analysed. Horses with ventral m...
Dynamics of Parascaris and Strongylus spp. parasites in untreated juvenile horses.
Veterinary parasitology    November 7, 2016   Volume 230 62-66 doi: 10.1016/j.vetpar.2016.11.002
Fabiani JV, Lyons ET, Nielsen MK.Parasite control in foals is of utmost importance due to the high susceptibility to parasitic infection and disease in this age group. Foals are commonly co-infected with strongyle and ascarid parasites, which complicate parasite control strategies. The present study retrospectively investigated necropsy records of foals born into a university herd kept without anthelmintic treatment since 1979. The aims were to statistically analyze the relationship between fecal egg counts, worm burdens, foal age, sex, and season with specific focus on Parascaris and Strongylus spp. A total of 83 foals born ...
Periparturient characteristics of mares and their foals on a New Zealand Thoroughbred stud farm.
New Zealand veterinary journal    October 24, 2016   Volume 65, Issue 1 24-29 doi: 10.1080/00480169.2016.1244021
Rosales C, Krekeler N, Tennent-Brown B, Stevenson MA, Hanlon D.To describe selected periparturient variables in a sample of Thoroughbred mares and their foals on a commercial stud farm in New Zealand. Methods: Data were collected for 969 foaling records, from 592 mares, by foaling attendants from one Thoroughbred stud farm in the Waikato region of New Zealand for the breeding seasons 2008-2013, inclusive, and collated retrospectively. The associations between mare- and foal-level variables and gestation length, time of birth (expressed as the number of hours after midday), fetal membrane retention time, time for the foal to stand and suckle after birth, a...
Factors associated with survival of horses following relaparotomy.
Equine veterinary journal    October 13, 2016   Volume 49, Issue 4 448-453 doi: 10.1111/evj.12635
Findley JA, Salem S, Burgess R, Archer DC.Relaparotomy may be required to investigate and manage complications that occur following surgical management of colic. Objective: To report factors associated with survival following relaparotomy. Methods: Retrospective cohort study. Methods: Records of horses that had undergone exploratory laparotomy for treatment of colic over a 10-year period (2002-2012) and had undergone relaparotomy <8 weeks following the initial surgery were reviewed. Descriptive data were generated and association with survival time was modelled using Cox proportional hazards models. Results: Relaparotomy was perfor...
Comparison of psyllium feeding at home and nasogastric intubation of psyllium and magnesium sulfate in the hospital as a treatment for naturally occurring colonic sand (geosediment) accumulations in horses: a retrospective study.
Acta veterinaria Scandinavica    October 12, 2016   Volume 58, Issue 1 73 doi: 10.1186/s13028-016-0254-z
Kaikkonen R, Niinistö K, Lindholm T, Raekallio M.Ingestion of geosediment (further referred as sand) may cause weight loss, diarrhea and acute or recurrent colic in horses. Our aim was to compare the efficacy of three treatment protocols in clearing colonic sand accumulations in clinical patients. This retrospective clinical study consisted of 1097 horses and ponies, which were radiographed for the presence of colonic sand. Horses included to the study (n = 246) were displaying areas of sand in the radiographs of ≥75 cm2 and were treated medically monitoring the response with radiographs. The horses were assigned into three groups base...
Electrochemotherapy as a single or adjuvant treatment to surgery of cutaneous sarcoid tumours in horses: a 31-case retrospective study.
The Veterinary record    October 7, 2016   Volume 179, Issue 24 627 doi: 10.1136/vr.103867
Tozon N, Kramaric P, Kos Kadunc V, Sersa G, Cemazar M.The aim of our study was to evaluate the efficacy of electrochemotherapy (ECT) with cisplatin as a single or adjuvant treatment for sarcoids in equids. Different treatment options with different success rates were proposed. Thirty-one horses and one donkey with different clinical type, size and location of tumours were treated with ECT as a single treatment (18 animals with 52 tumour nodules) or as adjuvant treatment with marginal surgical excision (14 animals with 18 tumour nodules). In animals treated only with ECT with cisplatin, complete response was obtained in 48/52 (92.3 per cent) nodul...
Objective assessment of the compensatory effect of clinical hind limb lameness in horses: 37 cases (2011-2014).
Journal of the American Veterinary Medical Association    October 5, 2016   Volume 249, Issue 8 940-944 doi: 10.2460/javma.249.8.940
Maliye S, Marshall JF.OBJECTIVE To characterize and describe the compensatory load redistribution that results from unilateral hind limb lameness in horses. DESIGN Retrospective case series. ANIMALS 37 client-owned horses. PROCEDURES Medical records were reviewed to identify horses with unilateral hind limb lameness that responded positively (by objective assessment) to diagnostic local anesthesia during lameness evaluation and that were evaluated before and after diagnostic local anesthesia with an inertial sensor-based lameness diagnosis system. Horses were grouped as having hind limb lameness only, hind limb and...
Use of large-scale veterinary data for the investigation of antimicrobial prescribing practices in equine medicine.
Equine veterinary journal    October 5, 2016   Volume 49, Issue 4 425-432 doi: 10.1111/evj.12638
Welsh CE, Parkin TDH, Marshall JF.As antimicrobial resistant bacterial strains continue to emerge and spread in human and animal populations, understanding prescription practices is key in benchmarking current performance and setting goals. Antimicrobial prescription (AP) in companion veterinary species is widespread, but is neither monitored nor restricted in the USA and Canada. The veterinary use of certain antimicrobial classes is discouraged in some countries, in the hope of preserving efficacy for serious human infections. Objective: The aim of this study was to ascertain the rate of prescription of a number of 'reserved'...
Risk factors associated with fatal injuries in Thoroughbred racehorses competing in flat racing in the United States and Canada.
Journal of the American Veterinary Medical Association    October 5, 2016   Volume 249, Issue 8 931-939 doi: 10.2460/javma.249.8.931
Georgopoulos SP, Parkin TD.OBJECTIVE To identify risk factors associated with fatal injuries in Thoroughbred racehorses in the United States and Canada. DESIGN Retrospective study. ANIMALS 1,891,483 race starts by 154,527 Thoroughbred racehorses at 89 racetracks in the United States and Canada from 2009 to 2013. PROCEDURES Data were extracted from the Equine Injury Database, which contained information for 93.9% of all official flat racing events in the United States and Canada during the 5-year observation period. Forty-four possible risk factors were evaluated by univariate then multivariable logistic regression to id...
Arthroscopy of the Dorsal and Plantar Pouches of the Tarsocrural Joint for the Treatment of Osteochondritis Dissecans in the Horse: Clinical Features and Follow-Up.
Veterinary surgery : VS    September 29, 2016   Volume 45, Issue 8 1049-1055 doi: 10.1111/vsu.12560
James O, Payne R, Bathe A, Greet T, Wylie C.To describe the clinical details and pathology within the dorsal and plantar pouches of the tarsocrural joint of a population of horses that underwent arthroscopic surgery for tarsocrural osteochondritis dissecans (OCD). Methods: Retrospective cohort study. Methods: Horses referred for arthroscopic treatment of tarsocrural OCD between 2005 and 2013 (102 horses; 144 joints). Methods: Case records of all horses that had tarsocrural arthroscopy for OCD at Rossdales Equine Hospital, Newmarket, United Kingdom were included. Cases from 3 ECVS Diplomates were included, 1 of whom routinely examined 70...
Conservative Management of Unilateral Fractures of the Mandibular Rami in Horses.
Veterinary surgery : VS    September 29, 2016   Volume 45, Issue 8 1063-1065 doi: 10.1111/vsu.12561
Jansson N.To report the outcome of conservative management of unilateral fractures of the mandibular rami in horses. Methods: Retrospective case series. Methods: 24 client-owned horses with unilateral mandibular fractures METHODS: Medical records (January 2000-January 2014) of horses with unilateral mandibular ramus fractures were retrieved. Only conservatively managed horses with follow-up information were included. Follow-up information on clinical outcome was retrieved from the medical records (n=11) or obtained by telephone interviews with the owners or trainers (n=13). Results: Twenty-three horses ...
Prevention of equine herpesvirus myeloencephalopathy – Is heparin a novel option? A case report.
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere    September 21, 2016   Volume 44, Issue 5 313-317 doi: 10.15653/TPG-150451
Walter J, Seeh C, Fey K, Bleul U, Osterrieder N.Equine herpesvirus myeloencephalopathy (EHM) is a severe manifestation of equine herpesvirus 1 (EHV-1) infection. Prevention and treatment of EHM during EHV-1 outbreaks is critical, but no reliable and tested specific medication is available. Due to the thromboischemic nature of EHM and due to the fact that EHV-1 entry in cells is blocked by heparin, it was hypothesized that this compound may be useful in reduction of EHM incidence and severity. Therefore, during an acute EHV-1 outbreak with the neuropathogenic G/D Pol variant, metaphylactic treatment with heparin to prevent EHM was initiated....
Laparoscopic Closure of the Nephrosplenic Space in Horses with Nephrosplenic Colonic Entrapment: Factors Associated with Survival and Colic Recurrence.
Veterinary surgery : VS    September 13, 2016   Volume 45, Issue S1 O60-O69 doi: 10.1111/vsu.12549
Nelson BB, Ruple-Czerniak AA, Hendrickson DA, Hackett ES.1) To identify factors associated with short-term survival and time to death after hospital discharge in horses with nephrosplenic entrapment (NSE). 2) To compare the frequency of recurrent colic episodes in horses with and without laparoscopic closure of the nephrosplenic space. Methods: Historical cohort with a nested case control. Methods: Client-owned horses. Methods: Medical records of horses treated for NSE from January 1, 2002 to June 1, 2014 were reviewed. Data collected included signalment, physical examination parameters, laboratory results, diagnostic findings, and treatments. Facto...
Techniques and Indications for Intraoperative Ultrasound in Horses.
Veterinary surgery : VS    September 13, 2016   Volume 45, Issue 7 936-942 doi: 10.1111/vsu.12537
Stack JD, Cousty M, Sanders R, David F.To describe our experience using intraoperative ultrasound for various conditions in horses. Methods: Retrospective case series. Methods: Horses (n=113). Methods: Medical records including surgical reports at 2 equine hospitals (2007-2013) were reviewed to identify ultrasound-assisted surgeries. The diagnosis, reasons for using intraoperative ultrasound, the technique employed, and the surgical procedure performed (e.g., synovial endoscopy, cut-down, resection, dissection, curettage, and implant placement/removal) were recorded for each surgery. Intraoperative ultrasound was used to mark the o...
Retrospective Evaluation of Hemithyroidectomy in 14 Horses.
Veterinary surgery : VS    September 6, 2016   Volume 45, Issue 7 949-954 doi: 10.1111/vsu.12540
Troillet A, Böttcher D, Brehm W, Scharner D.To describe the presentation, presurgical diagnostic findings, treatment, and outcome of horses with histologically confirmed, unilateral thyroid neoplasia. The complications, particularly laryngeal hemiplegia, were investigated. Retrospective case series. Client-owned horses (n=14). Medical records of horses presenting with a unilateral thyroid mass due to neoplasia from 2003-2015 were reviewed. Horses must have undergone preoperative clinical evaluations that included ultrasound examination of the mass and upper airway endoscopy. Short-term follow-up at 2 weeks after surgery and owner questi...
Heritability and prevalence of selected osteochondrosis lesions in yearling Thoroughbred horses.
Equine veterinary journal    September 4, 2016   Volume 49, Issue 3 282-287 doi: 10.1111/evj.12613
Russell J, Matika O, Russell T, Reardon RJ.Osteochondrosis is considered multifactorial in origin, with factors such as nutrition, conformation, body size, trauma and genetics thought to contribute to its pathogenesis. Few studies have investigated the effects of genetic variability of osteochondrosis in Thoroughbreds. Objective: To describe the prevalence and genetic variability of a subset of osteochondrosis lesions in a group of Thoroughbred yearlings. Methods: Retrospective cohort study. Methods: Radiographs of 1962 Thoroughbred yearlings were retrieved from clinical records obtained between 2005 and 2013. Pedigree information was ...
Comparison of clinical findings and short-term survival between horses with intestinal entrapment in the gastrosplenic ligament and horses with intestinal entrapment in the epiploic foramen.
Journal of the American Veterinary Medical Association    September 2, 2016   Volume 249, Issue 6 660-667 doi: 10.2460/javma.249.6.660
Kilcoyne I, Dechant JE, Nieto JE.OBJECTIVE To compare clinical findings and short-term outcome for horses with intestinal entrapment in the gastrosplenic ligament (GLE) with those of horses with intestinal entrapment in the epiploic foramen (EFE). DESIGN Retrospective case-control study. ANIMALS 43 horses with GLE (cases) and 73 horses with EFE (controls). PROCEDURES Medical records of horses examined because of colic at a veterinary teaching hospital between 1992 and 2012 were reviewed. Signalment was extracted from medical records for all horses with colic (colic population), and additional information regarding colic histo...
A retrospective analysis of antimicrobial resistance in bacterial pathogens in an equine hospital (2012-2015).
Schweizer Archiv fur Tierheilkunde    August 10, 2016   Volume 158, Issue 6 433-442 doi: 10.17236/sat00068
van Spijk JN, Schmitt S, Fürst AE, Schoster A.Antimicrobial resistance has become an important concern in veterinary medicine. The aim of this study was to describe the rate of antimicrobial resistance in common equine pathogens and to determine the occurrence of multidrug-resistant isolates. A retrospective analysis of all susceptibility testing results from bacterial pathogens cultured from horses at the University of Zurich Equine Hospital (2012-2015) was performed. Strains exhibiting resistance to 3 or more antimicrobial categories were defined as multidrug-resistant. Susceptibility results from 303 bacterial pathogens were analyzed, ...
Retrospective Analysis of the Equine Influenza Virus A/Equine/Kirgizia/26/1974 (H7N7) Isolated in Central Asia.
Pathogens (Basel, Switzerland)    August 10, 2016   Volume 5, Issue 3 55 doi: 10.3390/pathogens5030055
Karamendin K, Kydyrmanov A, Sayatov M, Strochkov V, Sandybayev N, Sultankulova K.A retrospective phylogenetic characterization of the hemagglutinin, neuraminidase and nucleoprotein genes of equine influenza virus A/equine/Kirgizia/26/1974 (H7N7) which caused an outbreak in Kirgizia (a former Soviet Union republic, now Kyrgyzstan) in 1977 was conducted. It was defined that it was closely related to the strain London/1973 isolated in Europe and it shared a maximum nucleotide sequence identity at 99% with it. This Central Asian equine influenza virus isolate did not have any specific genetic signatures and can be considered as an epizootic strain of 1974 that spread in Europe...
Risk Factors for Equine Gastric Glandular Disease: A Case-Control Study in a Finnish Referral Hospital Population.
Journal of veterinary internal medicine    July 28, 2016   Volume 30, Issue 4 1270-1275 doi: 10.1111/jvim.14370
Mönki J, Hewetson M, Virtala AM.Equine gastric glandular disease (EGGD) is a term used to classify erosive and ulcerative diseases of the glandular mucosa of the equine stomach. Epidemiologic studies of risk factors for EGGD have not been reported. Objective: To determine risk factors for EGGD. Methods: Cases (n = 83) had endoscopic evidence of EGGD; controls (n = 34) included healthy horses and horses with equine squamous gastric disease (ESGD) without EGGD. Methods: Retrospective case-control study. The data were analyzed by multivariable logistic regression modeling. Analysis was performed on the full dataset. An addi...
Use of a laparoscopic specimen retrieval pouch to facilitate removal of intact or fragmented cystic calculi from standing sedated horses: 8 cases (2012-2015).
Journal of the American Veterinary Medical Association    July 22, 2016   Volume 249, Issue 3 304-310 doi: 10.2460/javma.249.3.304
Katzman SA, Vaughan B, Nieto JE, Galuppo LD.OBJECTIVE To evaluate the use of a laparoscopic specimen retrieval pouch for removal of intact or fragmented cystic calculi from standing horses. DESIGN Retrospective case series. ANIMALS 8 horses (5 geldings and 3 mares) with cystic calculi. PROCEDURES Physical examination and cystoscopic, ultrasonographic, and hematologic evaluations of urinary tract function were performed for each horse. A diagnosis of cystic calculus was made on the basis of results of cystoscopy and ultrasonography. Concurrent urolithiasis or other urinary tract abnormalities identified during preoperative evaluation wer...
Treatment of sarcoids in equids: 230 cases (2008-2013).
Journal of the American Veterinary Medical Association    July 22, 2016   Volume 249, Issue 3 311-318 doi: 10.2460/javma.249.3.311
Haspeslagh M, Vlaminck LE, Martens AM.OBJECTIVE To evaluate outcomes following treatment of sarcoids in equids and to identify risk factors for treatment failure in these patients. DESIGN Retrospective case series. ANIMALS 230 equids with 614 sarcoids. PROCEDURES Records were searched to identify equids treated for ≥ 1 sarcoid between 2008 and 2013. A standardized protocol was used to determine treatment choice (electrosurgery, electrosurgery with intralesional placement of cisplatin-containing beads, topical administration of imiquimod or acyclovir, cryosurgery, bacillus Calmette-Guerin vaccine injection, or intralesional injec...
Ex Vivo Computed Tomographic Evaluation of Morphology Variations in Equine Cervical Vertebrae. Veraa S, Bergmann W, van den Belt AJ, Wijnberg I, Back W.Diagnostic imaging is one of the pillars in the clinical workup of horses with clinical signs of cervical spinal disease. An improved awareness of morphologic variations in equine cervical vertebrae would be helpful for interpreting findings. The aim of this anatomic study was to describe CT variations in left-right symmetry and morphology of the cervical and cervicothoracic vertebrae in a sample of horses. Postmortem CT examinations of the cervical spine for horses without congenital growth disorders were prospectively and retrospectively recruited. A total of 78 horses (27 foals, 51 mature h...
Comparisons Between Staphylectomy and Tie-Forward Procedures in Combination with a Sternothyroideus Myotenectomy for the Treatment of Intermittent Dorsal Displacement of the Soft Palate: An Observational Study.
Veterinary surgery : VS    July 13, 2016   Volume 45, Issue 6 816-823 doi: 10.1111/vsu.12518
Carmalt JL, Johanssen B, Waldner C.To compare the performance of horses with intermittent dorsal displacement of the soft palate (IDDSP) treated surgically with a control group and to determine whether there was a difference in postoperative performance between horses treated with a staphylectomy or a tie-forward procedure. Methods: A retrospective observational study. Methods: Swedish Warmblood trotting horses (Standardbreds) with endoscopically confirmed IDDSP (n=56) and control horses (n=48) with endoscopically normal upper airways tested using overground endoscopy identified from medical records. Methods: Generalized estima...
A retrospective review of hyperaesthetic leucotrichia in horses in the USA.
Veterinary dermatology    July 5, 2016   Volume 27, Issue 4 294-e72 doi: 10.1111/vde.12327
Goodale EC, White SD, Outerbridge CA, Everett AD, Affolter VK.Hyperaesthetic leucotrichia (HL) rarely affects horses and causes painful lesions on the dorsum that result in leucotrichia. This may be a variant of erythema multiforme (EM), but there are no studies investigating this condition. Objective: Describe the clinical and histological features of HL and compare them to the histological features of EM. Methods: A retrospective review of medical records from 1985 to 2015 identified 15 horses with HL. Thirteen biopsies of HL and five of EM were evaluated and compared. Results: Arabian horses and their crosses (χ(2) (1)  = 8.56, P < 0.01) and A...
Mineralization of the Equine Palmar/Plantar Annular Ligament Treated by Surgical Resection.
Veterinary surgery : VS    July 1, 2016   Volume 45, Issue 5 602-608 doi: 10.1111/vsu.12503
Garvican ER, Wylie CE, Payne RJ, Smith RK, Head MJ.To document the clinical presentation, diagnosis, and surgical treatment of mineralization of the equine palmar/plantar annular ligament (PAL). Methods: Retrospective study. Methods: Ponies (n=7). Methods: Case records from 2 referral hospitals were examined to identify cases with lameness associated with PAL mineralization treated surgically. Follow-up information was obtained from the owners by telephone questionnaire. Results: Duration of lameness before referral ranged from 5 weeks to 6 months, and degree of lameness from grade 1 to 5 out of 10. In 3 cases, records noted obvious pain when ...
Echocardiographic Assessment of Left Atrial Size and Function in Warmblood Horses: Reference Intervals, Allometric Scaling, and Agreement of Different Echocardiographic Variables.
Journal of veterinary internal medicine    June 30, 2016   Volume 30, Issue 4 1241-1252 doi: 10.1111/jvim.14368
Huesler IM, Mitchell KJ, Schwarzwald CC.Echocardiographic assessment of left atrial (LA) size and function in horses is not standardized. Objective: The aim of this study was to establish reference intervals for echocardiographic indices of LA size and function in Warmblood horses and to provide proof of concept for allometric scaling of variables and for the clinical use of area-based indices. Methods: Thirty-one healthy Warmblood horses and 91 Warmblood horses with a primary diagnosis of mitral regurgitation (MR) or aortic regurgitation (AR). Methods: Retrospective study. Echocardiographic indices of LA size and function were meas...
Optimized methods for extracting circulating small RNAs from long-term stored equine samples.
Acta veterinaria Scandinavica    June 29, 2016   Volume 58, Issue 1 44 doi: 10.1186/s13028-016-0224-5
Unger L, Fouché N, Leeb T, Gerber V, Pacholewska A.Circulating miRNAs in body fluids, particularly serum, are promising candidates for future routine biomarker profiling in various pathologic conditions in human and veterinary medicine. However, reliable standardized methods for miRNA extraction from equine serum and fresh or archived whole blood are sorely lacking. We systematically compared various miRNA extraction methods from serum and whole blood after short and long-term storage without addition of RNA stabilizing additives prior to freezing. Time of storage at room temperature prior to freezing did not affect miRNA quality in serum. Fur...
[Occurrance of antibodies against Leptospira in horses in Middle Germany].
Berliner und Munchener tierarztliche Wochenschrift    June 28, 2016   Volume 129, Issue 5-6 202-208 
Pikalo J, Sattler T, Eichinger M, Loitsch A, Sun H, Schmoll F, Schusser GF.Aim of the study was to detect antibodies and potential risk factors for an infec- tion with Leptospira in horses in Middle Germany. Serum samples of 314 horses were examined retrospectively by microscopic agglutination test for the presence of antibodies against eight Leptospira serovars. In total, 17.2% (n = 54) of the horses were positive for one or more of the serovars analyzed. The most prevalent serovar was lcterohaemorrhagiae (11.1%), followed by serovar Bratislava (9.6 %) and Grippotyphosa (1.9%). Mares showed a significantly higher occurrence of antibodies (p < 0.05) than geldings ...
Efficacy of combination therapy with anti-thymocyte globulin and cyclosporine A as a first-line treatment in adult patients with aplastic anemia: a comparison of rabbit and horse formulations.
International journal of hematology    June 23, 2016   Volume 104, Issue 4 446-453 doi: 10.1007/s12185-016-2046-7
Suzuki T, Kobayashi H, Kawasaki Y, Okazuka K, Hatano K, Fujiwara S, Oh I, Ohmine K, Kanda Y.Anti-thymocyte globulin (ATG) is a key drug in immunosuppressive therapy for patients with aplastic anemia. The mainstay of ATG therapy had been a horse ATG (hATG) formulation, Lymphoglobulin or ATGAM, but Lymphoglobulin was recently discontinued, and Thymoglobulin, a rabbit ATG (rATG) formulation, is currently used as the first-line drug in many countries, including Japan. However, a recent randomized clinical trial reported significantly unfavorable outcomes associated with the use of rATG regimens. We retrospectively analyzed clinical outcomes of adult patients with moderate to severe aplas...
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