Veterinary care in horses encompasses the medical and preventive measures taken to maintain and improve the health and well-being of equine patients. It includes a wide range of practices such as routine health examinations, vaccinations, dental care, parasite control, and management of injuries and diseases. Veterinary care also involves diagnostic procedures, surgical interventions, and therapeutic treatments tailored to the specific needs of horses. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of equine veterinary care, including advancements in diagnostic techniques, treatment protocols, and health management strategies to support the well-being and performance of horses.
Hampson BA, Connelley AD, de Laat MA, Mills PC, Pollitt CC.To determine solar load-bearing structures in the feet of feral horses and investigate morphological characteristics of the sole in feral horses and domestic Thoroughbreds. Methods: Forelimbs from cadavers of 70 feral horses and 20 domestic Thoroughbreds in Australia. Methods: Left forefeet were obtained from 3 feral horse populations from habitats of soft substrate (SS [n = 10 horses]), hard substrate (HS [10]), and a combination of SS and HS (10) and loaded in vitro. Pressure distribution was measured with a pressure plate. Sole depth was measured at 12 points across the solar plane in feet ...
Näreaho A, Vainio K, Oksanen A.In order to assess the resistance situation against macrocyclic lactones in Parascaris equorum and against tetrahydropyrimidine derivatives in strongyles in Finnish trotter horses, 112 foals on 18 farms, mostly 1 year old, were examined for these parasites with a modified McMaster faecal flotation method. P. equorum positive foals (n=24) were given ivermectin orally at a dose of 200 μg/kg b.w., while strongyle positive but P. equorum negative foals (n=38) received pyrantel embonate orally at a dose of 19 mg/kg. Sixteen P. equorum infected foals, treated with ivermectin, also harboured strongy...
Vallance SA, Bell RJ, Spriet M, Kass PH, Puchalski SM.To date, few reports exist comparing magnetic resonance imaging (MRI) and computed tomography (CT) for imaging of the equine distal limb, yet clinicians are required to decide which modality to use regularly. Objective: To report and compare anatomic visualisation scores obtained for CT, contrast enhanced CT (CECT) and standing low-field MRI (LFMRI) in the equine foot. Objective: Anatomic visualisation score discrepancies would exist between CT, CECT and LFMRI. Methods: Images of 22 lame horses (31 limbs) undergoing both CT and LFMRI of the foot were reviewed. When available, CECT images were ...
Franklin SH, Barakzai SZ, Couroucé-Malblanc A, Dixon P, Nankervis KJ, Perkins JD, Roberts CA, Vanerck-Westergren E, Allen KJ.During the past 20 years, treadmill exercise testing has played an important role in both the study of equine exercise physiology and the investigation of poor athletic performance. However, it has been suggested that some trainers and veterinarians may be reluctant to refer horses for treadmill exercise testing because of fears that horses may be at increased risk of musculoskeletal injury during treadmill exercise. Objective: To investigate the incidence and types of injuries sustained by horses undergoing treadmill exercise. Methods: Data were collated from 9 centres in the UK, France and B...
Votion DM, Fraipont A, Goachet AG, Robert C, van Erck E, Amory H, Ceusters J, de la Rebière de Pouyade G, Franck T, Mouithys-Mickalad A, Niesten A....Limited information exists about the muscle mitochondrial respiratory function changes that occur in horses during an endurance season. Objective: To determine effects of training and racing on muscle oxidative phosphorylation (OXPHOS) and electron transport system (ETS) capacities in horses with high resolution respirometry (HRR). Methods: Mitochondrial respiration was measured in microbiopsies taken from the triceps brachii (tb) and gluteus medius (gm) muscles in 8 endurance horses (7 purebred Arabians and 1 crossbred Arabian) before training (T0), after two 10 week training periods (T1, T2)...
Butudom P, Foreman JH, Kline KH, Whittem EL.Some methods of lactate (LA) measurement have not been validated appropriately for use in horses. Objective: To validate 2 LA analysers (YSI 2300 Stat Plus and TDx Lactic Acid Assay) for use with equine plasma and to compare plasma [LA] determined by the 2 methods. Methods: Both instruments were evaluated for linearity, parallelism, recovery and precision using serial dilutions of standard LA solutions and equine plasma and then comparing results with linear regression or paired t tests. Plasma [LA] results were compared in 275 blood samples collected from horses exercising at various intensit...
De Graaf-Roelfsema E, Keizer HA, Wijnberg ID, Van Der Kolk JH.Gastric ulceration can be caused by different pathophysiological mechanisms including dietary factors, psychological stress and exercise. Overtraining is a medical syndrome in performance horses associated with altered hormone levels, altered feed intake, altered behaviour and decreased performance. These components might lead to a higher incidence of gastric ulceration in overtrained horses. Objective: To investigate whether the incidence of gastric ulceration is increased in overtrained compared to control horses. Methods: A longitudinal training study with twelve 1.5 years old Standardbred ...
Waller AP, Pearson W, Lindinger MI.Standardbred and Thoroughbred racehorses around the world are tested for performance enhancing substances. Among these are blood alkalising substances that raise plasma pH and total carbon dioxide (TCO(2)) concentration. However, many horses have an elevated TCO(2) due to dietary, environmental and health concerns without having been administered an alkalising substance. Objective: The purposes of this study were to determine the acid-base profile of a cross section of Standardbred horses in racing/race training in Ontario and the main independent variables that contributed to acid-base state....
Ely ER, Price JS, Smith RK, Wood JL, Verheyen KL.A previous study has identified exercise undertaken during training to be associated with racing performance in flat racehorses. However, no such studies have been conducted in National Hunt (NH) horses. Objective: To determine whether exercise undertaken during training is associated with racing performance in NH racehorses. Methods: Data were collected as part of a larger study investigating injury occurrence in NH racehorses. Race records and daily exercise data were obtained from NH racehorses at 14 training yards. Canter, gallop and race distances accumulated in the 30 days preceding a 'c...
Hill EW, Eivers SS, McGivney BA, Fonseca RG, Gu J, Smith NA, Browne JA, MacHugh DE, Katz LM.The role of molecular signalling pathways in the phenotypic adaptation of skeletal muscle to different exercise stimuli in the Thoroughbred horse has not been reported previously. Objective: To examine CKM, COX4I1, COX4I2 and PDK4 gene expression following high intensity sprint and moderate intensity treadmill exercise stimuli in skeletal muscle of Thoroughbred horses. Methods: Two groups of trained 3-year-old Thoroughbred horses participated. Group A (n = 6 females, n = 3 males) participated in an incremental step test (moderate intensity) to fatigue or HR(max) on a Sato high speed treadmill ...
Scott R, Nankervis K, Stringer C, Westcott K, Marlin D.Water treadmill exercise is often incorporated into rehabilitation programmes for horses yet little is known about the biomechanical and physiological responses to water walking. Objective: To establish whether stride frequency (SF) reached steady state as a result of 6 introductory water treadmill sessions and then to investigate the effect of increasing water height on SF, stride length (SL) and heart rate (HR). Methods: Nine horses with no previous experience of water treadmills completed 6 sessions of walking for between 15 and 30 min. Each horse was fitted with a leg mounted accelerometer...
Sleutjens J, Voorhout G, Van Der Kolk JH, Wijnberg ID, Back W.In dressage, the head and neck position has become an issue of concern as certain extreme positions may imply a welfare risk for the horse. In man, extension and flexion of the cervical spine cause a decrease and increase in intervertebral foramina dimensions, respectively. However, in horses, the influence of flexion and extension on foramina dimensions and its possible interference with peripheral nerve functioning remains unknown. Objective: To determine the effect of ex vivo flexion and extension on intervertebral foramina dimensions in the equine cervical spine. Methods: Computed tomograp...
Ohmura H, Mukai K, Takahashi T, Matsui A, Hiraga A, Jones JH.Accumulated O(2) deficit (AOD) and plasma lactate accumulation rate (PLAR) are alternative methods for estimating net anaerobic energy utilisation (NAEU) in exercising horses. How they compare or their accuracy is unknown. Objective: We hypothesised net anaerobic energy utilisation calculated by PLAR (NAUE(PLAR)) is equivalent to NAUE estimated by AOD (NAUE(AOD)). Methods: Six Thoroughbred horses ran at identical supramaximal speeds (118% aerobic capacity) until exhaustion for 2 runs while breathing normoxic (NO, 21% O(2)) or hyperoxic (HO, 26% O(2)) gas. Jugular blood was sampled at 15 s inte...
Jönsson L, Dalin G, Egenvall A, Näsholm A, Roepstorff L, Philipsson J.Disturbances in skeletal development, primarily osteochondrosis (OC) and palmar/plantar osseous fragments (POF), have been commonly reported as problems in young horses. However, there are few reports of such findings for epidemiological analyses or breeding purposes. Objective: To evaluate equine hospital data as a possible source of information for genetic evaluations by estimating prevalence and heritability of OC in the stifle, hock and fetlock joints and of POF in the fetlock. Methods: Data on Swedish Warmblood (SWB) horses were obtained from a large equine hospital in south Sweden. Preva...
Liburt NR, Adams AA, Betancourt A, Horohov DW, McKeever KH.Studies have demonstrated increases in mRNA expression for inflammatory cytokines following exercise in horses and have suggested those markers of inflammation may play a role in delayed onset muscle soreness. However, measurement of mRNA expression in white blood cells is an indirect method. No studies to date have documented the cytokine response to exercise directly in muscle in horses. Objective: This study tested the hypothesis that exercise increases cytokine markers of inflammation in blood and muscle. Methods: Blood and muscle biopsies were obtained from 4 healthy, unfit Standardbred m...
Thomsen MH, Persson AB, Jensen AT, Sørensen H, Andersen PH.Equine lameness examination is based on subjective visual scoring of lameness. Instrumented objective methods for lameness examinations may be complicated to perform and the equipment is often stationary. Accelerometry has a potential clinical use; however, the reduction and interpretation of equine accelerometric data are not yet routine and the value of accelerometry in equine lameness examination is unclear. Objective: To use accelerometric data to calculate 2 different accelerometric symmetry scores and to evaluate the agreement of these with traditional lameness scores done by experienced...
Haussler KK, Martin CE, Hill AE.Spinal mobilisation and spinal manipulative therapy (SMT) are being applied to horses; however, there are limited objective measures of their effects on spinal mobility or stiffness in actively ridden horses. Objective: To quantify passive spinal movements induced during dorsoventral mobilisation of the trunk and to identify any potential effects of SMT on measures of spinal mobility within the thoracolumbar region in standing horses. We hypothesise that displacement amplitudes will be significantly increased across vertebral levels after SMT, compared to spinal mobilisation only within the co...
Silver IA, Jeffcott LB, Rossdale PD.The British Equine Veterinary Association (BEVA) was established in 1961 and launched the Equine Veterinary Journal (EVJ) in 1968. This review outlines some of the major advances in equine science and practice that have occurred in that time and the role played by the Journal in facilitating those developments.
Nagy A, Murray JK, Dyson S.Endurance is the fastest growing Féderation Équestre International (FEI) discipline and the large number of eliminations on veterinary grounds needs to be investigated. Objective: To document elimination rates and explore potential risk factors for elimination due to lameness or metabolic reasons in 9 countries representing 5 continents. Methods: Data for rides of ≥ 100 km ('elite endurance rides') in Australia, France, Italy, South Africa, Spain, United Arab Emirates (UAE), UK, Uruguay and USA were collected from the FEI website. Data were collected for all started horses on the country, ...
Muñoz A, Riber C, Trigo P, Castejón-Riber C, Castejón FM.Limited information exists concerning the defence of homeostasis during endurance competitions and the relationship with performance. Objective: This research analysed renin (REN), angiotensin II (ANG), aldosterone (ALD) and vasopressin (AVP) in horses covering different distances, assesses differences between successful and eliminated horses and evaluates correlations between hydration status, renal function, electrolytes, REN, ANG, ALD and AVP. Methods: Packed cell volume (PCV), velocity and serum concentrations of REN, ANG, ALD, AVP, Na, K, Cl, Ca, Mg, P, creatine kinase, aspartate aminotra...
Geor RJ, Stewart-Hunt L, McCutcheon LJ.There is limited information about factors regulating glucose utilisation post exercise in horses. Objective: To determine the effects of a single bout of moderate intensity exercise on measures of insulin-mediated (IMGU) and noninsulin-mediated (NIMGU) glucose uptake during a hyperglycaemic clamp (HC). Methods: Hyperglycaemic clamps were administered in random order to 8 Standardbreds under 4 conditions: 1) rest, insulinopenia (R-L); 2) rest, hyperinsulinaemia (R-H); 3) post exercise (45 min at ∼ 50% VO2peak), insulinopenia (Ex-L) and 4) post exercise, hyperinsulinaemia (Ex-H). In the R-L a...
Urschel KL, Geor RJ, Waterfall HL, Shoveller AK, McCutcheon LJ.Providing protein or amino acid mixtures in combination with glucose to post exercise in man has resulted in increases in the post feeding insulin response and in muscle glycogen and protein synthesis rates. However, whether protein and/or amino acids can modify the post exercise insulin responses in horses remains to be fully elucidated. Objective: To determine whether whey protein or leucine addition to a glucose solution affects the post gavage plasma insulin, glucose and amino acid responses in horses and whether these responses are different following a period of exercise vs. rest. Method...
Barnes A, Kingston J, Beetson S, Kuiper C.This study investigated the physiology of endurance horses competing in warm weather over technical terrain, a situation where horses may become metabolically compromised. Objective: There will be changes in physiological, haematological and biochemical variables as horses progress through the 160 km ride and horses detected clinically at the veterinary inspections as metabolically compromised will have significant differences in measured laboratory variables compared to horses that complete the ride successfully. Methods: Forty-eight horses competing in the Australian Tom Quilty 160 km endura...
Trachsel DS, Bitschnau C, Waldern N, Weishaupt MA, Schwarzwald CC.Frequent supraventricular or ventricular arrhythmias during and after exercise are considered pathological in horses. Prevalence of arrhythmias seen in apparently healthy horses is still a matter of debate and may depend on breed, athletic condition and exercise intensity. Objective: To determine intra- and interobserver agreement for detection of arrhythmias at rest, during and after exercise using a telemetric electrocardiography device. Methods: The electrocardiogram (ECG) recordings of 10 healthy Warmblood horses (5 of which had an intracardiac catheter in place) undergoing a standardised ...
Meyer ND, Bayly WM, Sides RH, Wardrop KJ, Slinker BK.Prolonged equine exercise can cause hypochloraemic alkalosis and hypokalaemia secondary to the loss of hypertonic sweat. Movement of ions in and out of erythrocytes during exercise may help regulate acid-base balance and changes in plasma ion concentrations. The extent to which this happens during prolonged equine exercise has not been reported. Objective: To measure changes in blood gases and major plasma and intraerythrocytic (iRBC) ion concentrations of horses undergoing prolonged submaximal exercise. Methods: Six horses were trotted at ∼ 30% VO2max on a treadmill for 105 min. Arterial ((...
McKenzie EC, Garrett RL, Payton ME, Riehl JH, Firshman AM, Valberg SJ.Dantrolene sodium is used to prevent exertional rhabdomyolysis in predisposed horses. Food intake might negatively impact dantrolene bioavailability in horses; however, prolonged feed restriction might be detrimental to performance. Objective: To determine a minimum duration of feed restriction that would optimise plasma dantrolene concentrations in horses after nasogastric administration. It was hypothesised that feed restriction for 4, 8 or 12 h before dantrolene administration would result in higher plasma dantrolene concentrations than achieved with no feed restriction before treatment. Me...
Barrey E.Equine breeding selection has been developed by applying quantitative genetic methods for calculating the heritability of the complex traits such as performance in racing or sport competitions. With the great development of biotechnologies, equine molecular genetics has come of age. The recent sequencing of the equine genome by an international consortium was a major advance that will impact equine genomics in the near future. With the rapid progress in equine genetics, new applications in early performance evaluation and the detection of disease markers become available. Many new biomolecular...
Kemmink A, Westermann CM, van der Kolk JH.The quantity of glucose disposal during exercise (walk and trot) compared to rest by use of the hyperglycaemic clamp technique has not been reported previously and has relevance to nutritional requirements. Objective: Exercise (walk and trot) significantly increases glucose disposal compared to rest. Methods: Seven healthy Dutch Warmblood mares, all in dioestrus, mean ± s.d. age 11.6 ± 2.4 years and weighing 569 ± 40 kg were fasted for 12 h prior to a hyperglycaemic clamp at rest (maintaining a steady state of the blood glucose concentration during 30 min), walk (10 min, 1.5 m/s), trot (20 ...
Byström A, Stalfelt A, Egenvall A, Von Peinen K, Morgan K, Roepstorff L.Saddle fit is well recognised as an important factor for the health and performance of riding horses. However, only few studies have addressed general effects of different saddle construction details within a group of horses. Objective: To assess the influence of girth strap placement, traditional vs. v-system, and panel flocking material, wool vs. synthetic foam, on the saddle pressure pattern during riding. Methods: Six horses were ridden by 3 riders in sitting and rising trot and sitting canter. Saddle pressure was measured with 3 different saddle variants: 1) wool flocked panels and tradit...
Hill C, Crook T.Massage is widely used in physiotherapy, but there has been little previous research examining its effectiveness in increasing equine soft tissue length. Objective: To determine the effect of massage on equine hindlimb protraction. We hypothesised that massage to the caudal muscles of the equine hindlimb, specifically the superficial gluteal, semitendinosus, biceps femoris and semimembranosus muscles, can increase passive and active hindlimb protraction. Methods: The study used a crossover design in which 8 horses were randomly assigned to 2 groups of 4, A and B. Group A received massage for 3...
Pearson H, Pinsent PJ, Polley LR, Waterman A.Four cases of fatal diaphragmatic rupture in the horse are described. In 2 cases there was no history of injury but the other 2 animals had sustained recent thoracic trauma. Three of the horses had signs of colic and bowel obstruction complicated, in 2 cases, by respiratory embarrassment; the fourth died rapidly, presumably of shock. Previously published cases are reviewed and the causes, clinical effects, diagnosis and treatment of the disorder are discussed.
Johnson PJ, Goetz TE.A 10-month-old Standard-bred colt was examined because of weight loss, fever, and extensive subcutaneous edema of the ventral aspects of its trunk. Diagnosis of granulomatous enteritis was based on D-xylose malabsorption, hypoproteinemia, and rectal mucosal biopsy. Campylobacter fetus subsp fetus was cultured from jugular venous blood when the horse was admitted to the hospital and 24 hours later. Appropriate antimicrobial agents and glucocorticoids failed to effect clinical remission. After euthanasia, granulomatous enteritis was confirmed at necropsy but C fetus subsp fetus was not isolated ...
McIlwraith CW.This paper reviews the current status of diagnostic and surgical arthroscopy in the horse. Arthroscopy has been used as a diagnostic aid since 1974 and is useful for evaluation of abnormalities in synovial membrane and articular cartilage. Surgical arthroscopy is a more recent advance that has replaced conventional arthrotomy in 90 per cent of the author's cases. Clinical conditions currently being treated using arthroscopic techniques rather than arthrotomy include all chip fractures in the carpus, chip fractures of the first phalanx, chronic proliferative synovitis in the fetlock and osteoch...
Hill T, Carmichael D, Maylin G, Krook L.The incidences of fractures and soft tissue injuries during 68397 starts of thoroughbred horses at New York Racing Association tracks were analyzed concerning track condition, dirt and turf tracks, environmental conditions, length of races, location of fractures on the track, and age of horses. It was concluded that the conditions evaluated are of no importance in the occurrence of racing injuries to thoroughbred horses.
Jann HW, Hart JC, Stein LE, Ritchey J, Blaik M, Payton M, Fackelman GE, Rezabek GB, Mann BK.To assess the effects of a crosslinked, modified hyaluronic acid (xCMHA-S) gel on equine tendon healing using an in vivo surgical model. Methods: In vivo experimental study. Methods: Adult horses (n = 5). Methods: Full thickness bilateral forelimb window tenectomies were surgically created in both forelimb superficial digital flexor tendons and xCMHA-S gel was implanted intraoperatively into the right forelimb lesion of each horse whereas the left forelimb served as the untreated control. Healing was monitored by serial ultrasound examinations every 14 days over the course of the 84 day st...
Collodel G, Rinaldi S, Moretti E, Fontani V, Castagna A, Iacoponi F, Terzuoli G, C뻝u F, Careddu GM, Cossu I, Passino ES.The Radio Electric Asymmetric Conveyer (REAC) has been mostly applied to treat symptoms related to psychological stress. In the study, we demonstrated the effect of REAC-Veterinary Neuro Psycho Physical Optimization (VNPPO) treatment protocol on sperm parameters of subfertile (n=11) and fertile (n=4) stallions. Subfertile stallions showed a reduced sperm concentration, progressive motility and normal morphology compared to fertile stallions. An increase in progressive sperm motility and quality of sperm morphology was found in subfertile stallions after the REAC-VNPPO treatment. The positive e...
Bixby-Hammett DM.In brief: In a two-year study of the estimated 13,428,000 hours of horse activities by 18,408 US Pony Clubs (USPC) members aged 6 to 21 in scheduled supervised programs, there were 64 accidents resulting in 88 injuries in 16 areas of the body. The head/face was the area most often injured (27.27%), and bruise/abrasion was the most common type of injury (28.26%). Cross-country riding was the most dangerous event (42.31%). Unexpected actions of the horse caused many accidents-25% occurred when the horse bucked and threw the rider, 23.08% when the horse refused a jump, and 17.31% when the horse f...
Luethy D, Slack J, Kraus MS, Gelzer AR, Habecker P, Johnson AL.Third-degree atrioventricular block (AVB) and primary inflammatory myocarditis are uncommon findings in horses. The horse of this report presented for collapse at rest and was found to have multiple cardiac arrhythmias, most notably 3rd-degree AVB. The horse was subsequently diagnosed with eosinophilic myocarditis on necropsy, a rare form of myocarditis not previously reported in horses. Despite extensive testing, an etiologic agent could not be identified, illustrating the difficulty in identifying a specific cause of myocarditis in horses.
Meade BJ, Timoney PJ, Donahue JM, Branscum AJ, Ford R, Rowe R.In 1998, a newly identified bacterium Taylorella asinigenitalis was isolated from the external genitalia and reproductive tracts of nurse mares, a stallion and donkey jacks in Kentucky. An extensive regulatory effort was implemented to contain the outbreak including the tracing and testing of 232 horses and donkeys on 58 premises. T. asinigenitalis was isolated from the reproductive tract of 10 adult equids, including two donkey jacks, one Paint Quarter-horse stallion and seven draft-type breeding mares. None of the infected horses had clinical signs of reproductive tract disease. The odds of ...
Roberts MC, Groenendyk S.Splenectomy was successfully performed on 2 aged horses to facilitate experimental studies of Babesia equi infection. Resection of part of the 17th rib provided the most acceptable approach and avoided many complications encountered on removing part of the 16th rib.
Monreal L, Villatoro AJ, Monreal M, Espada Y, Anglés AM, Ruiz-Gopegui R.Thirty healthy male horses were allotted to 3 groups and treated blindly during 4 days. Group-1 horses received unfractioned calcium heparin (100 IU/kg of body weight, SC, q 12 h). Group-2 horses received a single dose of a low-molecular-weight heparin (50 anti-Xa IU/kg, SC) every morning, and a similar volume of saline solution every evening. Group-3 horses received the vehicle (saline solution), SC, every 12 hours. Citrated and EDTA-anticoagulated blood samples were collected before starting the medication (T-0) and once daily 3 hours after each morning injection (T-3, T-27, T-51, and T-75)....
Escartin-Peña M, Bautista-Garfias CR.Sera from 41 horses and 159 donkeys, from twelve States of México, were tested to ascertain anti-Gasterophilus circulating antibodies by double immunodiffusion (DD), counterimmunoelectrophoresis (CIE), indirect haemagglutination (IH), thin layer immunoassay (TIA) and diffusion-in-gel ELISA (DIG-ELISA) methods using crude somatic antigen from third instar larvae of G. intestinalis (DeGeer). At necropsy, 33/41 horses and 24/159 donkeys were found to be parasitized by G. intestinalis and/or G. nasalis (L.). Gasterophilus intestinalis was the species most commonly found in the equines. Analysis o...
Palacios H, Hibarren I, Olalla MJ, Cala V.The diagnosis of lead poisoning in horses living on farmland in the vicinity of a battery recycling plant was based on clinical signs as well as on laboratory findings. Chemical analysis of six surface soils (0-15 cm) and herbage samples taken at different distances to the recycling plant showed very high total lead levels in the closest sites to the facility and a clear decrease with distance. Total lead levels in soil samples ranged from 127 to 5657 mg kg(-1), with more than 70% of lead extractable by EDTA in the most polluted soils. Lead levels in the aerial part of herbage samples were in ...
Honnas CM, Spensley MS, Laverty S, Blanchard PC.An 18-year-old mare, 285 days pregnant, was evaluated for apparent abdominal pain of 8 hours' duration. A large volume of sanguinous fluid was obtained on abdominocentesis, and digital vaginal examination revealed a dilated cervix and blood in the uterus. Abdominal palpation per rectum revealed the uterus to be large and distended with fluid. Ultrasonography revealed a dead fetus on the floor of the cranial portion of the abdomen. The mare was euthanatized, and necropsy confirmed that the uterus had ruptured, and that the fetus, within its chorioallantois, was in the abdomen. The amniotic sac ...
Doxey DL, Gilmour JS, Milne EM.Local weather patterns associated with 15 outbreaks of equine grass sickness in eastern Scotland were studied. The majority showed a trend toward cooler drier weather associated with irregular ground frosts. This would not preclude the hypothesis that fungi might be connected with the aetiology of grass sickness.
Kailaanmäki A, Kinnunen T, Kwok WW, Rytkönen-Nissinen M, Randell J, Virtanen T.The responses of allergen-specific CD4(+) T cells of allergic and healthy individuals are still incompletely understood. Our objective was to investigate the functional and phenotypic properties of CD4(+) T cells of horse-allergic and healthy subjects specific to the immunodominant epitope region of the major horse allergen Equ c 1. Specific T-cell lines (TCLs) and clones were generated from peripheral blood mononuclear cells with Equ c 1(143-160), the peptide containing the immunodominant epitope region of Equ c 1. The frequency, proliferative response, cytokine production and HLA restriction...
Perdrizet JA, Scott DW.Cellulitis and subcutaneous abscess formation was diagnosed in a 3-month-old Thoroughbred filly. Clinical signs consisted of a large ulcerated plaque, with satellite pustules on the medial aspect of the right hock and subcutaneous abscesses in the right inguinal and mammary gland areas. Laboratory analysis revealed mature neutrophilia. Rhodococcus equi was isolated from the cellulitis and the subcutaneous abscess. Oral administration of erythromycin and rifampin for 35 days resulted in a clinical cure.
Merritt AM, Panzer RB, Lester GD, Burrow JA.The pelvic flexure is the midpoint of the equine large colon that marks the junction of dorsal and ventral components. Previous studies of intraluminal pressure in this region indicate that it could be an important motility control center. The present study was undertaken to expand our knowledge of normal myoelectric activity around the pelvic flexure region. Eight bipolar silver wire electrodes were surgically fixed at 5-cm intervals to the colonic serosa of five adult horses, starting 30 cm oral to the pelvic flexure on the left ventral colon and ending 15 cm aboral to the pelvic flexure on ...
Delesalle C, Deprez P, Schuurkes JA, Lefebvre RA.The use of human prokinetic drugs in colic horses leads to inconsistent results. This might be related to differences in gastrointestinal receptor populations. The motor effects of 5-hydroxytryptamine (5-HT; serotonin) on the equine mid-jejunum were therefore studied. Longitudinal muscle preparations were set up for isotonic measurement. 5-HT induced tonic contractions with superimposed phasic activity; these responses were not influenced by tetrodotoxin and atropine, suggesting a non-neurogenic, non-cholinergic pathway. The 5-HT receptor antagonists GR 127935 (5-HT(1B,D)), ketanserin (5-HT(2A...
Hayakawa Y, Komae H, Ide H, Nakagawa H, Yoshida Y, Kamada M, Kataoka Y, Nakazawa M.An acute death occurred in a racehorse with pneumonia after long-distance transportation in December, 1990. Pasteurella caballi, Streptococcus suis and Streptococcus zooepidemicus were isolated from the lung at high rate. Specific antigens of these bacteria were also demonstrated immunohistologically in the pneumonic lesion. These findings indicated that the disease is equine transport pneumonia caused by a mixed infection of the three bacterial species. This is the first report on the isolation of P. caballi and S. suis from a racehorse in Japan.
Beste KJ, Lawhon SD, Chamoun-Emanuelli AM, Duff AH, Coleman MC, Griffin CE, Hardy J, Whitfield-Cargile CM.Horses with bacterial sinusitis frequently undergo empirical treatment with antimicrobials, however, in some cases bacterial culture of the affected sinus is used to direct therapy. Data regarding which organisms are part of the commensal microbiota of the equine sinus are lacking making it difficult to interpret culture results and guide empiric antimicrobial selection. Objective: Our objectives were to describe the bacterial and fungal microbiota of the paranasal sinuses in clinically normal horses using culture-dependent and independent approaches and to compare the bacterial culture and su...