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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Hoof horn abnormalities in Lipizzaner horses and the effect of dietary biotin on macroscopic aspects of hoof horn quality.
Equine veterinary journal    May 1, 1995   Volume 27, Issue 3 175-182 doi: 10.1111/j.2042-3306.1995.tb03060.x
Josseck H, Zenker W, Geyer H.This study involved a macroscopic evaluation of hoof quality in 152 Lipizzaner horses (130 from Austria and 22 from other countries) and a controlled double blind trial of the effects of biotin on hoof horn growth and quality over 19 months in 42 stallions from the Spanish Riding School (SRS) in Vienna. Using a grading system that incorporated evaluation of horn wall, white line, sole and frog, the macroscopic study revealed the following: 90% of the Austrian Lipizzaners had soft white lines and crumbling, fissured horn at the bearing border of the walls; 39% of the stallions of the SRS, > ...
Epidemiological aspects of equine babesioses in a herd of horses in Brazil.
Veterinary parasitology    May 1, 1995   Volume 58, Issue 1-2 1-8 doi: 10.1016/0304-4017(94)00704-g
Pfeifer Barbosa I, Böse R, Peymann B, Friedhoff KT.Epidemiological studies of Babesia equi and B. caballi were undertaken in a herd of 120 pastured horses in Rio de Janeiro, Brazil. The area where the horses were held was shown to be highly endemic for both Babesia spp., i.e. the prevalence of B. equi antibodies in horses aged 6 months or older ranged from 90.6% to 100% as determined by the immunofluorescence antibody (IFA) test, and the prevalence of B. caballi antibodies as determined by Western blot ranged from 59.4% to 65.5%. From the herd, 20 foals and their dams were selected to estimate the degree of tick infestation and the foals were ...
Mechanical evaluation of transosseous wire rope configurations in a large animal external fixator.
American journal of veterinary research    May 1, 1995   Volume 56, Issue 5 694-699 
Rapoff AJ, Markel MD, Vanderby R.By use of wire ropes as the transosseous component, an external skeletal fixator for the repair of long bone fractures in horses and cattle has been designed and tested in axial compression. Theoretical methods were used in the design process to size fixator components; however, our results suggest that conventional methods of analyzing the displacement of the transosseous component may not apply to wire ropes. Large pretensions in the wire ropes are necessary to obtain functional stiffnesses for fracture fixation. Therefore, a method was sought for terminating the ropes so that an appropriate...
Bilateral synovial chondromatosis of the metatarsophalangeal joints in a pony.
Equine veterinary journal    May 1, 1995   Volume 27, Issue 3 234-238 doi: 10.1111/j.2042-3306.1995.tb03068.x
Smith RK, Coumbe A, Schramme MC.No abstract available
Tumour necrosis factor, equine arthritis and clinical research.
Equine veterinary journal    May 1, 1995   Volume 27, Issue 3 160-161 doi: 10.1111/j.2042-3306.1995.tb03056.x
May SA.No abstract available
Detection of clenbuterol (Ventipulmin) in the horse.
Zentralblatt fur Veterinarmedizin. Reihe A    May 1, 1995   Volume 42, Issue 3 209-219 doi: 10.1111/j.1439-0442.1995.tb00372.x
Hagedorn HW, Zuck S, Schulz R.An enzyme linked immunosorbent assay (ELISA) was developed to detect the beta 2-agonist clenbuterol in equine blood and urine. The antiserum was raised in rabbits, employing clenbuterol-diazo-BSA as antigen. Clenbuterol-diazo-horseradish peroxidase served as enzyme conjugate. The concentration of clenbuterol to decrease tracer binding by 50% (IC50 value) was found to be 27.50 +/- 4.20 pg/well (1.37 ng/ml). The antibody cross-reacted with salbutamol (30%), terbutaline (14%) and cimaterol (1%). Horse serum was used directly to screen for clenbuterol, while urine was employed diluted. Positive sc...
Primary closure of equine laryngotomy incisions: a review of 42 cases.
Veterinary surgery : VS    May 1, 1995   Volume 24, Issue 3 226-230 doi: 10.1111/j.1532-950x.1995.tb01322.x
Boulton EP, Seeherman HJ, Kirker-Head CA, Steckel RR.Laryngotomy incisions for either staphylectomy, ventriculectomy, cordectomy, resection of the palatopharyngeal arch, or subepiglottal cyst removal, were closed primarily in 42 horses. Incisional complications were subcutaneous emphysema (11 horses, 26%), incisional discharge (4 horses, 10%), postoperative fever (4 horses, 10%), incisional abscessation (3 horses, 7%), incisional seroma (2 horses, 5%), and subcutaneous edema (2 horses, 5%). Incisional complications were identified in 22 horses, but only 8 horses (19%) required intervention for incisional healing to occur. Factors such as preoper...
Eastern equine encephalitis in horses in Ontario in 1994.
The Canadian veterinary journal = La revue veterinaire canadienne    May 1, 1995   Volume 36, Issue 5 322 
Carman S, Hazlett M, Wilson R, Van Dreumel T, Thomson G, Mullaney T, Mahdy MS.No abstract available
Systemic and colonic venous plasma eicosanoid and endotoxin concentrations, and colonic venous serum tumor necrosis factor and interleukin-6 activities in horses during low-flow ischemia and reperfusion of the large colon.
American journal of veterinary research    May 1, 1995   Volume 56, Issue 5 656-663 
Moore RM, Muir WW, Cawrse M, Bertone AL, Beard WL.Twenty-four horses were randomly allocated to 3 groups. Horses were anesthetized, subjected to a ventral midline celiotomy, and the large colon was exteriorized and instrumented. Group-1 horses served as sham-operated controls. Group-2 horses were subjected to 6 hours of low-flow colonic arterial ischemia, and group-3 horses were subjected to 3 hours of ischemia and 3 hours of reperfusion. Baseline (BL) samples were collected, then low-flow ischemia was induced by reducing ventral colonic arterial blood flow to 20% of BL. All horses were monitored for 6 hours after BL data were collected. Bloo...
Serum protein concentrations in horses with severe liver disease: a retrospective study and review of the literature.
Journal of veterinary internal medicine    May 1, 1995   Volume 9, Issue 3 154-161 doi: 10.1111/j.1939-1676.1995.tb03289.x
Parraga ME, Carlson GP, Thurmond M.The present retrospective study was undertaken to determine the frequency of hypoproteinemia and hypoalbuminemia in horses with natural occurring severe liver disease. The study represents a review of case records and laboratory data of 84 horses presented with acute or chronic liver disease to the University of California Veterinary Medical Teaching Hospital between 1973 and 1991. Forty horses (48%) had serum protein concentrations above the maximum reference value (7.7 g/dL). The increase in serum protein concentration was associated with hyperglobulinemia (P = .00005, R2 = .80). Only 13% (1...
Kinetic studies and production rate of melatonin in pony mares.
The American journal of physiology    May 1, 1995   Volume 268, Issue 5 Pt 2 R1236-R1241 doi: 10.1152/ajpregu.1995.268.5.R1236
Guillaume D, Rio N, Toutain PL.The aims of the present study were to determine basic kinetic parameters and the nycthemeral production rate of melatonin in the horse. Seven pony mares were used for the kinetic studies. Five other pony mares were used under long and short days for the production rate studies. Melatonin was administered by intravenous, oral, and intragastric routes at different dose levels. The plasma melatonin clearance was 1.02 +/- 0.31 l.kg-1.h-1, and the volume of distribution was 0.89 +/- 0.53 l/kg for the 0.4 microgram/kg melatonin dose. The systemic availability after oral and intragastric administrati...
Stability of penicillin G, ampicillin, amikacin and oxytetracycline and their interactions with food in in vitro simulated equine gastrointestinal contents.
Research in veterinary science    May 1, 1995   Volume 58, Issue 3 227-231 doi: 10.1016/0034-5288(95)90107-8
McKellar QA, Horspool LJ.Penicillin G was extensively (84.7 per cent) and amikacin moderately (14.4 per cent) degraded when incubated for one hour in a chloride buffer at pH 1.9 designed to mimic the equine gastric pH. Ampicillin and oxytetracycline were stable at pH 1.9. Penicillin and ampicillin were moderately stable (more than 90 per cent) when incubated in equine caecal liquor for three hours but were degraded by about 65 per cent after 24 hours. More than 80 per cent of the initial concentrations of amikacin and oxytetracycline were recovered after 24 hours' incubation in equine caecal liquor. The concentrations...
Response to demineralized bone matrix implantation in foals and adult horses.
American journal of veterinary research    May 1, 1995   Volume 56, Issue 5 649-655 
Douglas J, Clarke A.Equine demineralized bone matrix, particle size 2 to 4 mm, was implanted SC and IM in 4 foals and 4 adult horses. The implants were removed between 5 and 8 weeks after implantation. Bone formation was induced by SC and IM implantations in all animals. The implantation site had a marked effect on the amount of bone that developed, bone being formed earlier and in greater amounts when the matrix was implanted IM. The amount of bone formed increased with increasing time after matrix implantation at both sites. Demineralized bone matrix implantation also led to formation of small amounts of chondr...
Cytologic evaluation of bronchoalveolar lavage fluid obtained from standardbred racehorses with inflammatory airway disease.
American journal of veterinary research    May 1, 1995   Volume 56, Issue 5 562-567 
Moore BR, Krakowka S, Robertson JT, Cummins JM.Cytologic examination of bronchoalveolar lavage fluid (BALF), including phenotypic analysis of lymphocytes, was performed on 32 Standardbreds with poor race performance and endoscopic examination findings characteristic of inflammatory airway disease (IAD). Nucleated cell counts in BALF from IAD-affected horses were higher than those in control horses; the cytologic profile of BALF in affected horses included mixed inflammation, characterized by mild neutrophilia, lymphocytosis, and monocytosis. Eosinophil and mast cell counts were not higher in the IAD-affected group, compared with those in t...
Effects of dimethyl sulfoxide, allopurinol, 21-aminosteroid U-74389G, and manganese chloride on low-flow ischemia and reperfusion of the large colon in horses.
American journal of veterinary research    May 1, 1995   Volume 56, Issue 5 671-687 
Moore RM, Muir WW, Bertone AL, Beard WL, Stromberg PC.Thirty horses were randomly assigned to 1 of 5 groups. All horses were anesthetized and subjected to ventral midline celiotomy, then the large colon was exteriorized and instrumented. Colonic arterial blood flow was reduced to 20% of baseline (BL) and was maintained for 3 hours. Colonic blood flow was then restored, and the colon was reperfused for an additional 3 hours. One of 5 drug solutions was administered via the jugular vein 30 minutes prior to colonic reperfusion: group 1, 0.9% NaCl; group 2, dimethyl sulfoxide: 1 g/kg of body weight; group 3, allopurinol: 25 mg/kg; group 4, 21-aminost...
Variations in urinary gamma glutamyl transferase/urinary creatinine ratio in horses with or without pleuropneumonia treated with gentamicin.
Equine veterinary journal    May 1, 1995   Volume 27, Issue 3 217-220 doi: 10.1111/j.2042-3306.1995.tb03065.x
Rossier Y, Divers TJ, Sweeney RW.The urinary GGT/urinary creatinine (uGGT/uCR) ratio was measured on Days 1, 3 and 10 in 4 adult, healthy horses; in 6 adult, healthy horses treated with gentamicin at recommended dosages and 9 adult horses treated for pleuropneumonia with gentamicin at recommended dosages. Plasma creatinine and gentamicin trough concentrations were measured on the same days. The uGGT/uCr ratio was higher in the normal horses (mean +/- s.d. 22.85 +/- 13.69) than previously reported normal values (10.5 +/- 6.8) (Adams and McClure 1985). Analysis of variance for repeated measures was used to compare the ratio in ...
Confidential enquiry of perioperative equine fatalities (CEPEF-1): preliminary results.
Equine veterinary journal    May 1, 1995   Volume 27, Issue 3 193-200 doi: 10.1111/j.2042-3306.1995.tb03062.x
Johnston GM, Taylor PM, Holmes MA, Wood JL.The Confidential Enquiry into Perioperative Equine Fatalities (CEPEF-1) is an observational multi-institutional prospective study of recovery outcome at 7 days post operatively, as called for by Steffey (1991). Data from 6,255 general anaesthetics (February 91-March 93) were submitted confidentially by 62 clinics. The outcomes of 333 cases which were subjected to euthanasia and which were not classified 'alive' or 'died' at 7 days, were excluded from the analysis. The remaining 5922 cases were analysed to identify risk ratios (RR) between survivors and nonsurvivors for a variety of factors. Th...
Selection of follicles, preculture oocyte evaluation, and duration of culture for in vitro maturation of equine oocytes.
Theriogenology    May 1, 1995   Volume 43, Issue 7 1141-1153 doi: 10.1016/0093-691x(95)00086-n
Del Campo MR, Donoso X, Parrish JJ, Ginther OJ.Equine oocytes (n = 537) were collected from slaughterhouse ovaries (n = 118 mares) by scraping the internal follicular wall. Preculture record was made of the appearance of oocyte investments (no cumulus, corona radiata only, compact cumulus, expanded cumulus), appearance of cytoplasm (homogeneous, condensed heterogeneous/fragmented), and nuclear maturation stages (germinal vesicle, germinal-vesicle breakdown, metaphase I, metaphase II, degenerated). There was no difference between follicles > 30 mm and follicles < or = 30 mm in the preculture frequency distribution among the 5 nuclear stages...
[Consequences of a surgical correction of an insufficient closure of the vulva on genital flora and conception rate in mares].
DTW. Deutsche tierarztliche Wochenschrift    May 1, 1995   Volume 102, Issue 5 183-187 
Heilkenbrinker T, Schubert TS, Oetjen J, Pózvári M, Frerking H.In this thesis the influence of pneumo-vagina on the microbiological colonization of the genital tract and their manifestation in cytological smears was examined. For mares with poor vulval conformation a comparison of the bacterial growth before and after plastic surgery of the vulva and vestibulum was carried out, as well as the registration of conception rates after operation and insemination. The biggest reduction of the bacterial content in the reproductive tract was found between vestibulum and cranial section of the vagina. The increased number of contaminant bacteria in the cranial sec...
Effect of phenytoin on skeletal muscle from quarter horses with hyperkalaemic periodic paralysis.
Research in veterinary science    May 1, 1995   Volume 58, Issue 3 206-211 doi: 10.1016/0034-5288(95)90103-5
Beech J, Fletcher JE, Tripolitis L, Lindborg S, Dawso T.The contractile activity, the threshold for calcium-induced calcium release in fractions of sarcoplasmic reticulum and the potassium concentration were determined in preparations of semimembranosus muscle from normal quarter horses and quarter horses with hyperkalaemic periodic paralysis before and after they were treated with phenytoin. Before the treatment there was no difference in caffeine contracture or electrically elicited twitch response between the two groups. For one week after the treatment, the time to peak tension of caffeine contractures was significantly (P < 0.005) reduced i...
Sodium channel inactivation is impaired in equine hyperkalemic periodic paralysis.
Journal of neurophysiology    May 1, 1995   Volume 73, Issue 5 1892-1899 doi: 10.1152/jn.1995.73.5.1892
Cannon SC, Hayward LJ, Beech J, Brown RH.1. Equine hyperkalemic periodic paralysis (E-HPP) is a dominantly inherited disorder of muscle that causes recurrent episodes of stiffness (myotonia) and weakness in association with elevated serum K+. Affected horses carry a mutant allele of the skeletal muscle isoform of the Na channel alpha-subunit. To understand how this mutation may cause the disease phenotype, the functional defect in Na channel behavior was defined physiologically by recording unitary currents from cell-attached patches on normal and affected equine myotubes. 2. The presence of the mutation was confirmed in our cell lin...
Equine pleuropneumonia.
The British veterinary journal    May 1, 1995   Volume 151, Issue 3 233-262 doi: 10.1016/s0007-1935(95)80175-8
Raidal SL.Pleuropneumonia is a clinically important equine disease, predisposed by a number of identifiable factors. Successful management is largely dependent on early identification and prompt initiation of appropriate treatment strategies. Rapid resolution of the disease process is associated with appropriate treatment commenced within 48 h of the causative insult. Lower airway contamination by oropharyngeal organisms and subsequent extension into the pulmonary parenchyma results in respiratory dysfunction and systemic toxaemia. Acute disease is associated with the isolation of facultatively anaerobi...
Systemic and colonic venous hemostatic alterations in horses during low-flow ischemia and reperfusion of the large colon.
American journal of veterinary research    May 1, 1995   Volume 56, Issue 5 664-670 
Moore RM, Couto CG, Muir WW, Moore BR, Kociba GJ.Twenty-four horses were randomly allocated to 3 groups. All horses underwent a ventral midline celiotomy, and the large colon was exteriorized and instrumented. Group-1 horses served as sham-operated controls, group-2 horses underwent 6 hours of colonic ischemia, and group-3 horses were subjected to 3 hours of ischemia and 3 hours of reperfusion. Baseline blood samples were collected, then low-flow colonic ischemia was induced in horses of groups 2 and 3 by reducing colonic arterial blood flow to 20% of baseline. All horses were monitored for 6 hours. Citrated systemic venous (SV) blood sample...
Blood gas values during intermittent positive pressure ventilation and spontaneous ventilation in 160 anesthetized horses positioned in lateral or dorsal recumbency.
Veterinary surgery : VS    May 1, 1995   Volume 24, Issue 3 266-276 doi: 10.1111/j.1532-950x.1995.tb01330.x
Day TK, Gaynor JS, Muir WW, Bednarski RM, Mason DE.One hundred sixty horses were anesthetized with xylazine, guaifenesin, thiamylal, and halothane for elective soft tissue and orthopedic procedures. Horses were randomly assigned to one of four groups. Group 1 (n = 40): Horses positioned in lateral (LRG1; n = 20) or dorsal (DRG1; n = 20) recumbency breathed spontaneously throughout anesthesia. Group 2 (n = 40): Intermittent positive pressure ventilation (IPPV) was instituted throughout anesthesia in horses positioned in lateral (LRG2; n = 20) or dorsal (DRG2; n = 20) recumbency. Group 3 (n = 40): Horses positioned in lateral (LRG3; n = 20) or d...
Microvascular permeability and endothelial cell morphology associated with low-flow ischemia/reperfusion injury in the equine jejunum.
American journal of veterinary research    May 1, 1995   Volume 56, Issue 5 639-648 
Dabareiner RM, Snyder JR, White NA, Pascoe JR, Harmon FA, Gardner I, Woliner MJ, Pinney D, Sullins KE.Microvascular permeability of the jejunum of clinically normal equids and microvascular permeability associated with 60 minutes of ischemia (25% baseline blood flow) and subsequent reperfusion were investigated. Eight adult horses were randomly allotted to 2 equal groups: normal and ischemic/reperfusion injury. Lymphatic flow rates, mesenteric blood flow, and lymph and plasma protein concentrations were determined at 15-minute intervals throughout the study. Microvascular permeability was determined by estimates of the osmotic reflection coefficient, which was determined when the ratio of lymp...
Twenty years of equine scintigraphy–a coming of age?
Equine veterinary journal    May 1, 1995   Volume 27, Issue 3 163-165 doi: 10.1111/j.2042-3306.1995.tb03057.x
Weaver MP.No abstract available
Tropane alkaloids and toxicity of Convolvulus arvensis.
Phytochemistry    May 1, 1995   Volume 39, Issue 2 301-303 doi: 10.1016/0031-9422(94)00969-z
Todd FG, Stermitz FR, Schultheis P, Knight AP, Traub-Dargatz J.Horses in a few, localized northern Colorado pastures exhibited weight loss and colic. At post mortem, intestinal fibrosis and vascular sclerosis of the small intestine was identified. The pastures where the affected horses grazed were overrun by field bindweed (Convolvulus arvensis). Bindweed from the pasture was found to contain the tropane alkaloids tropine, pseudotropine, and tropinone and the pyrrolidine alkaloids cuscohygrine and hygrine. Laboratory mice readily ate C. arvensis and exhibited a variety of abnormal clinical signs depending on the amount eaten. Similar alkaloids have been f...
Arthrodesis of the scapulohumeral joint in a horse.
The Canadian veterinary journal = La revue veterinaire canadienne    May 1, 1995   Volume 36, Issue 5 312-315 
MacDonald DG, Bailey JV, Fowler JD.No abstract available
The cloning and expression of the alpha subunit of equine glycoprotein hormones.
Biochemical Society transactions    May 1, 1995   Volume 23, Issue 2 347S doi: 10.1042/bst023347s
O'Brien M, Headon DR.No abstract available
Age related changes in biochemical markers of bone metabolism in horses.
Equine veterinary journal    May 1, 1995   Volume 27, Issue 3 201-207 doi: 10.1111/j.2042-3306.1995.tb03063.x
Price JS, Jackson B, Eastell R, Goodship AE, Blumsohn A, Wright I, Stoneham S, Lanyon LE, Russell RG.Biochemical markers of bone metabolism were analysed in serum samples obtained from 60 horses with no history of orthopaedic disease (age 3 months-20 years). Serum levels of the carboxyterminal propeptide of type I procollagen (PICP), a marker of bone formation and the pyridinoline cross linked telopeptide domain of type I collagen (ICTP), a putative marker of bone resorption, were measured by radioimmunoassay (RIA). Serum levels of the bone specific isoenzyme of alkaline phosphatase (BALP), another marker of bone formation, were measured by a wheatgerm agglutinin affinity (WGA) method. Total ...