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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Bilateral diaphragmatic paralysis in a pony.
Journal of the American Veterinary Medical Association    August 15, 1994   Volume 205, Issue 4 587-591 
Amory H, Lomba F, Lekeux PM, Solal AN, Jauniaux TP, Desmecht DJ.An adult pony had a 1-month history of severe respiratory distress that was resistant to treatment and environmental changes. Results of blood gas analysis were indicative of alveolar hypoventilation. Simultaneous recordings of thoracic and abdominal wall motion by inductance plethysmography, together with complete pulmonary mechanics evaluation that included transdiaphragmatic pressure monitoring, revealed complete passive behavior of the diaphragm during breathing. Because radiography, necropsy, and histologic examination did not reveal any major lesion to explain the clinical and functional...
Oestrus synchronisation and superovulation using equine FSH in crossbred ewes.
The Veterinary record    August 13, 1994   Volume 135, Issue 7 164-165 doi: 10.1136/vr.135.7.164
Sharma VK, Gupta RC, Khurana NK, Khar SK.No abstract available
Motor neuron disease in a quarter horse from Nova Scotia.
The Canadian veterinary journal = La revue veterinaire canadienne    August 1, 1994   Volume 35, Issue 8 507-509 
Lofstedt J, Ikede BO.No abstract available
Genetic analysis of equine rotavirus by RNA-RNA hybridization.
Journal of clinical microbiology    August 1, 1994   Volume 32, Issue 8 2009-2012 doi: 10.1128/jcm.32.8.2009-2012.1994
Imagawa H, Ishida S, Uesugi S, Masanobu K, Fukunaga Y, Nakagomi O.Serotype G3 equine rotaviruses isolated in Japan made up a common genogroup and were classified into two different genotypes. The genomes of serotype G3 equine rotaviruses with an identical electropherotype (isolated from 1982 to 1989) were very closely related to each other regardless of the year in which they were isolated. Serotype G3 equine rotavirus BI originating from England belonged to the same genogroup of serotype G3 equine rotaviruses isolated in Japan, although BI was classified as having a different genotype. The genomes of both serotype G10 equine rotavirus R-22 and serotype G10 ...
Temperature and pH effects on the oxygen equilibrium curve of the thoroughbred horse.
Respiration physiology    August 1, 1994   Volume 97, Issue 3 293-300 doi: 10.1016/0034-5687(94)90065-5
Smale K, Butler PJ.A new oxygen equilibrium curve is defined for the Thoroughbred horse under standard conditions of 37 degrees C, pH = 7.4 and PCO2 = 5.33 kPa. The "standard" P50 for the Thoroughbred is, at 2.83 +/- 0.04 (SE of mean) kPa, significantly lower than that found for the Hanoverian horse (3.17 +/- 0.03 kPa) by Clerbaux et al. (Can. J. Vet. Res. 50: 188-192, 1986), and lower than other values for horses in the literature. Using data from Butler et al. (J. Exp. Biol. 179: 159-180, 1993), curves were also constructed, in vitro, under simulated conditions of intense exercise to examine the individual eff...
African horsesickness: pathogenesis and immunity.
Comparative immunology, microbiology and infectious diseases    August 1, 1994   Volume 17, Issue 3-4 275-285 doi: 10.1016/0147-9571(94)90047-7
Burrage TG, Laegreid WW.African horsesickness (AHS) is a serious, non-contagious disease of horses and other solipeds caused by an arthropod-borne orbivirus of the family Reoviridae. In horses, AHS causes three distinct clinicopathologic syndromes, the pulmonary, cardiac and fever forms of the disease. Recent work has shown that the primary determinant of the form of disease expressed by naive horses is the virulence of the virus inoculum. Horses which recover from AHS exhibit solid humoral immunity against homologous challenge. Protective antibodies appear to be directed towards neutralizing epitopes on AHS virus VP...
Evaluation of a monoclonal antibody-based colony blot test for rapid identification of virulent Rhodococcus equi.
The Journal of veterinary medical science    August 1, 1994   Volume 56, Issue 4 681-684 doi: 10.1292/jvms.56.681
Takai S, Morishita T, Nishio Y, Sasaki Y, Tsubaki S, Higuchi T, Hagiwara S, Senba H, Kato M, Seno N.We recently generated a monoclonal antibody immunoglobulin G1 (MAb 10G5), which can recognize 15- to 17-kDa antigens, virulence-associated antigens of Rhodococcus equi, and developed a colony blot enzyme-linked immunosorbent assay with MAb 10G5 for the rapid identification of virulent R. equi. In this epidemiologic study, we evaluated the results of the colony blot test in the identification of virulent isolates of R. equi from feces of horses and soil and compared them with those from a conventional procedure (plasmid profiles of isolates by agarose gel electrophoresis). Environmental isolate...
The pharmacokinetics and pharmacodynamics of procainamide in horses after intravenous administration.
Journal of veterinary pharmacology and therapeutics    August 1, 1994   Volume 17, Issue 4 265-270 doi: 10.1111/j.1365-2885.1994.tb00243.x
Ellis EJ, Ravis WR, Malloy M, Duran SH, Smyth BG.Six horses were administered either 15 or 20 mg/kg body weight (b.w.) procainamide (PA) as an intravenous (i.v.) dose over 10 min. The plasma concentrations of PA and N-acetylprocainamide (NAPA) as well as the pharmacodynamic effect (prolongation of the QT interval) were monitored. The PA plasma concentrations could be described by a one-compartment model with a t1/2 of 3.49 +/- 0.61 h. The total body clearance of PA was 0.395 +/- 0.090 l/hr/kg and the volume of distribution was 1.93 +/- 0.27 l/kg. As observed after PA administration, NAPA (an active metabolite) had a t1/2 longer than PA of 6....
Equine dinucleotide repeat polymorphism at the VIAS-H7 locus.
Animal genetics    August 1, 1994   Volume 25, Issue 4 292 doi: 10.1111/j.1365-2052.1994.tb00221.x
Ewen KR, Matthews ME.No abstract available
Light chain isotype regulation in the horse. Characterization of Ig kappa genes.
Journal of immunology (Baltimore, Md. : 1950)    August 1, 1994   Volume 153, Issue 3 1099-1111 
Ford JE, Home WA, Gibson DM.Horse Ig kappa genes have been characterized to determine whether there may be a structural basis for the low level of kappa expression in this species. The overall organization of the J kappa-C kappa locus is remarkably similar to that of the mouse and human loci. A single C kappa exon is separated by 2.9 kb from five J kappa segments, four of which seem functional and three of which are associated with canonical recombination signal sequences. A highly conserved intron enhancer was identified upstream of the C kappa exon and a single restriction fragment in horse genomic DNA hybridized stron...
Application of PCR to a clinical and environmental investigation of a case of equine botulism.
Journal of clinical microbiology    August 1, 1994   Volume 32, Issue 8 1986-1991 doi: 10.1128/jcm.32.8.1986-1991.1994
Szabo EA, Pemberton JM, Gibson AM, Thomas RJ, Pascoe RR, Desmarchelier PM.PCR for the detection of botulinum neurotoxin gene types A to E was used in the investigation of a case of equine botulism. Samples from a foal diagnosed with toxicoinfectious botulism in 1985 were reanalyzed by PCR and the mouse bioassay in conjunction with an environmental survey. Neurotoxin B was detected by mouse bioassay in culture enrichments of serum, spleen, feces, and intestinal contents. PCR results compared well with mouse bioassay results, detecting type B neurotoxin genes in these samples and also in a liver sample. Other neurotoxin types were not detected by either test. Clostrid...
[The clinical case. Fjord foal, female, 1 day old. Anal atresia].
Tierarztliche Praxis    August 1, 1994   Volume 22, Issue 4 309-402 
No abstract available
The effects of butorphanol on locomotor activity in ponies: a preliminary study.
Journal of veterinary pharmacology and therapeutics    August 1, 1994   Volume 17, Issue 4 323-326 doi: 10.1111/j.1365-2885.1994.tb00253.x
Nolan AM, Besley W, Reid J, Gray G.No abstract available
Pregnancy-associated endometrial expression of antileukoproteinase gene is correlated with epitheliochorial placentation.
Molecular reproduction and development    August 1, 1994   Volume 38, Issue 4 357-363 doi: 10.1002/mrd.1080380402
Badinga L, Michel FJ, Fields MJ, Sharp DC, Simmen RC.Uterine expression of the mRNA encoding antileukoproteinase (ALP) is highest in pig uterus during mid- to late pregnancy, suggesting a stage of pregnancy-dependent role for this elastase/cathepsin G protease inhibitor in feto-maternal interactions. To examine a potential relationship between uterine synthesis of ALP and the type of placentation in mammalian species, the expression of ALP mRNA and/or protein in pregnant mares, cows, rats, and mice was evaluated. Genomic DNA and mRNA hybridization analyses were performed using a porcine ALP cDNA as probe. The concentration of ALP protein in repr...
Reactions to strangles vaccination.
Australian veterinary journal    August 1, 1994   Volume 71, Issue 8 257-258 doi: 10.1111/j.1751-0813.1994.tb03423.x
Smith H.No abstract available
Morphologic characteristics of equine endometrium classified as Kenney categories I, II, and III, using light and scanning electron microscopy.
American journal of veterinary research    August 1, 1994   Volume 55, Issue 8 1060-1065 
Ferreira-Dias G, Nequin LG, King SS.Pathologic changes in the endometrium of mares may be rated according to Kenney's method of classification. Category I endometrium contains healthy tissue with no or few widely scattered pathologic changes. At the opposite end, severe widespread pathologic changes are associated with category III. Uterine biopsy specimens were collected aseptically from 16 mares during the estrous and diestrous stages of the cycle. Pathologic changes were evaluated, using light microscopy, and endometrium was classified as Kenney's category I, II, or III. Endometrial tissue of category I (n = 5 mares in estrus...
Primary splenic lymphoma in a horse.
The Journal of veterinary medical science    August 1, 1994   Volume 56, Issue 4 767-769 doi: 10.1292/jvms.56.767
Tanimoto T, Yamasaki S, Ohtsuki Y.A well-demarcated solitary splenic mass (20 x 20 x 15 cm in size) containing hemorrhagic and necrotic foci was observed in a 4-year-old Thoroughbred stallion. Histologically, the mass consisted of lymphoma cells of the diffuse large non-cleaved type, with a high mitotic index and scattered macrophages that formed a starry sky pattern. The lymphoma cells revealed diffuse positivity for acid phosphatase and alpha naphthyl butyrate esterase, and were also positive for intracytoplasmic IgM on occasion, and mostly for proliferating cell nuclear antigen. Ultrastructural examination revealed moderate...
[Morphologic and molecular biologic studies of the etiology of equine sarcoid].
Tierarztliche Praxis    August 1, 1994   Volume 22, Issue 4 368-376 
Teifke JP.From 932 equine skin lesions 421 were diagnosed as sarcoids (about 45%). The most common locations were the ventral body regions, head, neck and sites of thin skin. Most often the fibroblastic type, less frequently the mixed type and most infrequent the verrucous type of sarcoid were diagnosed. Detection of BPV-DNA was performed by polymerase chain reaction (PCR) using an oligonucleotide primer pair located in the E5-open reading frame. DNA of BPV 1 and BPV 2 could be differentiated by digestion with restriction endonucleases. In 97 out of 108 sarcoids BPV-DNA was detected by PCR. Most samples...
[A comparison of cardiac stroke volume determination using the thermodilution method and PW-Doppler echocardiography for the evaluation of systolic heart function in the horse].
DTW. Deutsche tierarztliche Wochenschrift    August 1, 1994   Volume 101, Issue 8 312-315 
Stadler P, Kinkel N, Deegen E.In 14 horses without heart disease stroke volume determination were established by pulsed wave doppler echocardiography. Thermodilution and doppler echocardiography were used simultaneously. The doppler echocardiographic volume determinations were carried out in left and right outflow tracts. Echocardiographically Velocity Time Integral, Maximum Flow Velocity, Mean Flow Velocity and Acceleration Time were ascertained. To be able to compare heart volumes of horses with different body weight stroke volume was applied to 1 kg of body weight (= heart index). Heart Index determined with thermodilut...
Detection of aberrant alleles in the D-loop region of equine mitochondrial DNA by single-strand conformation polymorphism (SSCP) analysis.
Animal genetics    August 1, 1994   Volume 25, Issue 4 287 doi: 10.1111/j.1365-2052.1994.tb00211.x
Ishida N, Hirano T, Mukoyama H.No abstract available
Effect of bacterial lipopolysaccharides on sulfated glycosaminoglycan metabolism and prostaglandin E2 synthesis in equine cartilage explant cultures.
American journal of veterinary research    August 1, 1994   Volume 55, Issue 8 1127-1138 
MacDonald MH, Stover SM, Willits NH, Benton HP.The metabolic responses of equine articular cartilage to incubation with bacterial lipopolysaccharide (LPS) were studied, using explant cultures of articular cartilage obtained from the metatarsophalangeal joints of 15 horses, age of which ranged from 3 months to 20 years. For comparison, explants were also established from the metatarsophalangeal joints of 3 calves. Explants were cultured for 3 days in medium containing various concentrations of LPS from 0 (control) to 100 micrograms/ml. Glycosaminoglycan (GAG) released during the 3-day incubation was determined by a spectrophotometric assay,...
Motor neuron disease in a horse.
The Canadian veterinary journal = La revue veterinaire canadienne    August 1, 1994   Volume 35, Issue 8 522 
Moore A, Collatos C, Ortenburger A, Illanes O, Ikede B.No abstract available
Interaction of equine spermatozoa with oviduct epithelial cell explants is affected by estrous cycle and anatomic origin of explant.
Biology of reproduction    August 1, 1994   Volume 51, Issue 2 222-228 doi: 10.1095/biolreprod51.2.222
Thomas PG, Ball BA, Brinsko SP.Regulation of attachment of equine spermatozoa to homologous oviduct epithelium was investigated by co-culture of spermatozoa with oviductal epithelial cell explants. Stallion spermatozoa were incubated with explants derived from the isthmus and ampulla of follicular, postovulatory, and diestrous mares. Steroid treatments (estradiol, progesterone, or control) were applied across all explant groups. Estimates of motility and total numbers of attached spermatozoa were made 0.5, 24, and 48 h after initiation of co-culture. Equine spermatozoa attached by their rostral acrosomal region to both cili...
Superior check ligament desmotomy for treatment of superficial digital flexor tendonitis in thoroughbred and standardbred horses.
Australian veterinary journal    August 1, 1994   Volume 71, Issue 8 233-235 doi: 10.1111/j.1751-0813.1994.tb03417.x
Fulton IC, MacLean AA, O'Rielly JL, Church S.Bilateral superior check ligament desmotomy was performed on 31 Thoroughbred and 17 Standardbred horses as the sole method of treatment for superficial digital flexor tendonitis. Horses resumed racing between 6 and 19 months after surgery. Horses that were able to compete in 5 or more races without injury to the tendon again were considered to have had a successful return to racing. Twenty-five Thoroughbreds were suitable for later study and 13 of these (52%) raced on 5 or more occasions. Fifteen Standardbreds were suitable for later study and 10 of these (66%) raced on 5 or more occasions. Wi...
Diagnostic techniques for identification and documentation of tendon and ligament injuries.
The Veterinary clinics of North America. Equine practice    August 1, 1994   Volume 10, Issue 2 365-407 doi: 10.1016/s0749-0739(17)30361-9
Denoix JM.Conventional clinical examination remains of medical and economic value for diagnosis of soft tissue injuries in the equine athlete. This procedure requires concentration and rigor to establish the diagnosis, and, if possible, some experience to better evaluate the prognosis. None of the new imaging techniques can replace the physical examination, but each may provide additional information. These sophisticated methods are bringing considerable progress in the knowledge of locomotor injuries in the horse and a tremendous improvement in our ability to diagnose precisely lamenesses and limitatio...
Semi-quantitative analysis of hoof-strike in the horse.
Journal of biomechanics    August 1, 1994   Volume 27, Issue 8 997-1004 doi: 10.1016/0021-9290(94)90216-x
Hjertén G, Drevemo S.The initial forelimb loading of a horse trotting at 3.7 ms-1 on a treadmill was studied by use of an instrumented shoe, accelerometers and high-speed cinematography. At the beginning of the stance phase the forelimb was loaded successively from the hoof. This is suggested to be an important factor for effective shock force absorbency in the extremities. Shearing forces may appear in the carpus before the onset of the longitudinal loading of the limb. These forces are proposed to depend on speed, locomotion pattern and the friction and hardness of the surface. It is suggested that shearing forc...
Effect of seminal plasma on motion characteristics of epididymal and ejaculated stallion spermatozoa during storage at 5 degrees C.
DTW. Deutsche tierarztliche Wochenschrift    August 1, 1994   Volume 101, Issue 8 319-322 
Braun J, Torres-Boggino F, Hochi S, Oguri N.The objective of this experiment was to examine the effect of seminal plasma on motion characteristics of epididymal and ejaculated equine spermatozoa during storage at 5 degrees C. Epididymal spermatozoa were flushed with either seminal plasma or a skim milk-glucose extender. Ejaculated spermatozoa were collected with extender added 10 minutes after semen collection and addition of extender during ejaculation by placing 50 ml extender in the collection bottle. Semen samples were centrifuged and resuspended with a skim milk-glucose extender containing seminal plasma (0, 5 and 25%; v/v), prepar...
Genus-specific detection of salmonellae in equine feces by use of the polymerase chain reaction.
American journal of veterinary research    August 1, 1994   Volume 55, Issue 8 1049-1054 
Cohen ND, Neibergs HL, Wallis DE, Simpson RB, McGruder ED, Hargis BM.Members of the genus Salmonella were identified in feces from horses, using the polymerase chain reaction (PCR) and genus-specific oligonucleotide primers. Feces from healthy horses were determined to be culture-negative for Salmonella spp. Fecal samples were inoculated with known numbers of colony-forming units (CFU) of S anatum, S derby, S enteritidis, S heidelberg, S newport, and S typhimurium. The DNA was extracted from fecal samples and amplified by PCR, using genus-specific primers. Sensitivity of the assay extended to 10(3) CFU of Salmonella sp/g of feces; sensitivity of microbiologic c...
Thermal sensitivity of mares’ milk proteins.
The Journal of dairy research    August 1, 1994   Volume 61, Issue 3 419-422 doi: 10.1017/s0022029900030843
Bonomi F, Iametti S, Pagliarini E, Solaroli G.No abstract available
Epizootiology and vectors of African horse sickness virus.
Comparative immunology, microbiology and infectious diseases    August 1, 1994   Volume 17, Issue 3-4 287-296 doi: 10.1016/0147-9571(94)90048-5
Mellor PS.African horse sickness (AHS) virus causes a non-contagious, infectious, arthropod-borne disease of equines and is enzootic in sub-Saharan Africa. The major vectors are species of Culicoides but mosquitoes and ticks may be involved. Periodically the virus makes excursions beyond its enzootic zones but until recently has not been able to maintain itself outside these areas for more than 2-3 consecutive years. This is probably due to a number of factors including the absence of a long term vertebrate reservoir, the prevalence and seasonal incidence of the vectors and the efficiency of control mea...