Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Pascoe JR, Ferraro GL, Cannon JH, Arthur RM, Wheat JD.Of 235 Thoroughbred racehorses examined with a flexible fiberoptic endoscope within 2 hours of racing to determine the frequency of exercise-induced pulmonary hemorrhage (EIPH), 103 (43.8%) had various degrees of hemorrhage in the tracheal lumen. Two of these horses (0.8%) subsequently had blood flow from the nostrils. Blood seemed to originate from the lung. Statistical analysis of frequency data for 191 horses which finished in 1st, 2nd, and 3rd places did not show any relationship between EIPH and horse's age, sex, or finishing position. However, a trend toward an increased frequency of EIP...
Weaver BM, Webb AI.The halothane muscle/gas partition coefficients at 37 degrees C for 26 samples of eight different muscles from four horses were found to depend significantly on the fat content of the muscle sample with a regression coefficient of 1.913 (SEM 0.109) per per cent ether-extractable fat content. The blood/gas partition coefficients in 24 horses showed a significant dependence on plasma triglyceride concentration (regression coefficient 0.00084 (SEM 0.00033) per mg dl-1), an insignificant positive dependence on plasma free and total cholesterol concentration and, in a multiple regression analysis, ...
Stick JA, Derksen FJ, Scott EA.Cervical esophagostomy for tube feeding was evaluated in 11 ponies. Minor complications responded to supportive therapy in 8 ponies. Two died of complications, and 1 pony had a permanent fistula because of persistent infection. There was a positive correlation between the duration of tube feeding and the event of closure of the esophageal stoma after the tube was removed. There was no difference in the frequency of complications related to duration of tube feeding. When the distal end of the feeding tube was located in the thoracic portion of the esophagus, instead of in the stomach, tubes wer...
Burrows GE.Endotoxins are non-protein fragments of the cell wall of Gram-negative bacteria. They must be absorbed into the circulation to produce disease and systemic effects are similar, regardless of bacterial source. Absorption of endotoxins occurs in obstructive bowel disease and may play a significant part in determining the severity of the disease. Many of the responses to experimentally administered endotoxin are identical to those of bowel diseases or the horse and include circulatory, haematological and metabolic alterations. Therapeutic approaches are indirect and include many drugs currently e...
Webster JH, Baird JD, Gunawan M, Martin IC, Kelly JD.The susceptibility of a known thiabendazole-resistant population of small strongyles to anthelmintics of both benzimidazole and non-benzimidazole groups, was determined. In the first study, 42 horses infected with thiabendazole-resistant small strongyles were allocated to 6 groups. Treatment groups received one of the following anthelmintics: mebendazole, febantel, febantel plus trichlorphon, morantel tartrate, or a combination of thiabendazole, piperazine and trichlorphon. Morantel tartrate and the thiabendazole/piperazine/trichlorphon combination produced highly significant (p less than 0.00...
Brownlow MA, Hutchins DR, Johnston KG.Twenty horses, aged one to 17 years (mean age 6 years), presented for elective destruction and subsequently found at autopsy to have no significant peritoneal alterations, were used to determine a variety of reference values for peritoneal fluid. Samples were collected ante mortem or within 1 h post mortem. Each cavity contained 100 to 300 ml of usually clear, pale yellow fluid which in a clinical refractometer showed a mean specific gravity 1.010 (range 1.0081-1.0116) and mean (+/- standard deviation) total protein 7.7 +/- 3.6 g/litre. The mean total nucleated cell count (+/- sd) was 4.33 +/-...
Carakostas MC, Moore WE, Smith JE.A procedure with chromium-51 (51Cr) as the cell label that maintains high-cell viability for studying granulocyte kinetics in horses is described. The procedure combines and modifies several methods for isolating leukocytes and granulocytes for use in the horse when a large volume of labeled cells is required. Also described is an improved technique for measuring granulocyte specific activity in large serial blood samples, using a Ficoll-sedimentation method. The procedure should be useful for determining granulocyte kinetics in the horse, the only major domestic species for which such data ar...
Holmberg DL.Four horses with corneal perforations of various etiologies were presented for surgical correction. Pedicle grafts taken from the bulbar or palpebral conjunctiva were used to repair the defects. Two horses regained functional vision in the affected eyes while a third had significant impairment. The fourth eye, which had an intense uveitis pre and postoperative, became phthisic and blind.
Muylle E, Vandenhende C, Oyaert W, Thoonen H, Vlaeminck K.Thirty-two horses were examined with a history of poor performance and unthriftiness several months after the ingestion of feed containing monensin sodium. Cardiac abnormality was diagnosed in 8 cases and suspected in 4 others. Necropsy examinations were performed on 6 cases with marked clinical symptoms and evidence of circulatory failure was found. Marked cardiac myopathy and fibrosis was a consistent feature. It is concluded that ingestion of monensin sodium by horses may cause either acute death or delayed cardiac circulatory failure as a result of specific cardiac myodegeneration.
Tranquilli WJ, Manohar M, Thurmon JC, Manning JP.Long-term catheterisation of the coronary sinus using a specially designed catheter was accomplished in 6 ponies via a right lateral thoracotomy. The catheter comprised a 10 to 12 cm long stiff segment (Teflon) joined to a 100 cm length of pliable medical grade (vinyl) tubing. Catheters were kept functional up to 10 weeks postoperatively. Location of the catheter tip was verified by determining the oxygen tension of anaerobically withdrawn blood samples. Normal values of oxygen tension of the coronary sinus blood in ponies were similar to those reported for the dog, whereas oxygen content was ...
Purohit RC, Mysinger PW, Redding RW.A continuous series of electroencephalograms (EEG) was obtained from each of 6 mature horses which had been given xylazine and ketamine hydrochloride IV. Electrocardiograms and respiratory rates were also obtained. The EEG of the unsedated standing adult horse displayed a dominant fast activity in the range of 25-35 Hz, 5-30 microV superimposed over slower 1-4 Hz, 10-50 microV activity with occasional 10-14 Hz, 10-40 microV spindle-type activity. The xylazine-sedated horse displayed hypersynchronous EEG patterns, with the dominant activity being 1-3 Hz, 10-70 microV with overlying mixed freque...
Simpson CF, Buergelt CD.The alveoli of the lungs of 2 aborted foals contained elongated, dense bodies when examined histologically and by transmission and scanning electron microscopy. By light microscopy, the bodies (10 to 40 micrometers in size) stained intensely with the Gram stain, and up to 10 were present within an alveolus. Electron microscopy determined that such bodies were not cellular in origin but appeared to be a congealed fluid product composed of layers of fibrillar-like material. From the human literature, it was concluded that these intraalveolar bodies were probably congealed amniotic fluid.
Gunn HM.A modification of the histochemical reaction to demonstrate myosin adenosine triphosphatase activity in skeletal (striated) muscle was used to define the density of capillaries in transverse sections of 3 muscles (semitendinosus, diaphragm, and pectoralis transversus) of horses and dogs. Thoroughbred horses and Greyhound dogs, breeds noted for their speed in running, were compared with other members of their respective species. Thoroughbred cross horses were grouped with non-Thoroughbreds for comparison with Thoroughbreds. The area of muscle supplied by a capillary was remarkably similar in mu...
Joyner LP, Donnelly J, Huck RA.The results of complement fixation (CF) test for equine piroplasmosis on sera from horses destined for international movement from Great Britain and Ireland are presented and analysed. No horses born and continuously resident in the British Isles were found carrying CF antibodies to either Babesia equi or B caballi. Positive animals were found to have association with the following countries where known tick vectors occur: Spain, Portugal, Belgium, France, Poland, USSR and Arabian Gulf countries. Data on the persistence of CF antibodies in animals subjected to repeated testing showed that some...
Otcenásek M, Mátl J, Vítovec J, Vladík P, Wohlman J.A case of maduromycotic mycetoma (eumycetoma) in seven years old draught horse is described. The disease was localized in anal region and healed after surgical treatment. Attention is drawn to the necessity of distinguishing three types of mycosis in horses, characterized by the origin of tumor lesions - mycetomas, hyphomycosis and entomophthoromycosis - and information was gathered on their etiology and geographical occurrence. On the basis of the morphology of fungal elements traced in inflammated changed tissues and with regard to the existing findings on the origin of eumycetoma in animals...
Held JP, Daniel GB.The effect of flunixin meglumine on renal function was studied in 6 healthy horses by use of nonimaging nuclear medicine techniques. Effective renal plasma flow (ERPF) and effective renal blood flow (ERBF) were determined by plasma clearance of 131I-orthoiodohippuric acid before and after administration of flunixin meglumine. Mean ERPF and ERBF was 6.03 ml/min/kg and 10.7 ml/min/kg, respectively, before treatment and was 5.7 ml/min/kg and 9.7 ml/min/kg, respectively, after treatment. Although ERPF and ERBF decreased after flunixin meglumine administration, the difference was not statistically ...
Guthrie AJ, Van den Berg JS, Killeen VM, Nichas E.A practical test for evaluating the sweating response to various concentrations of the specific beta 2 agonist, salbutamol sulphate, is described. The results of performing this test on horses (n = 54) considered to be "free sweaters", horses (n = 6) that showed signs of heat stress following exercise, and horses with complete anhidrosis (n = 2) are presented. The results indicate that intradermal injections of 0.1 ml of salbutamol sulphate at dilutions of 10(-7) or less are suitable stimuli to elicit a visually detectable local sweating in horses with a normal sweating response. Horses that o...
Popović N, Djuricić B, Valcić M.A study of literature concerning Lyme borreliosis related to animals was done. In the research work the epidemiology, pathogenesis, diagnosis and treatment of horses, cattle and dogs affected with Lyme borreliosis have been discussed. The clinical signs of Lyme borreliosis in horses are: chronic weight loss, sporadic lameness, laminitis, low grade fever, swollen joints, muscle tenderness and anterior uvetitis. In addition to these clinical sings, neurological sings such as depression, behavioral changes, dysphagia and encephalitis can be seen in chronic cases. Cattle affected with acute Lyme b...
Respiratory diseases are a major cause of morbidity and mortality in the horses of all ages including foals. There is limited understanding of the expression of immune molecules such as tetraspanins and surfactant proteins (SP) and the regulation of the immune responses in the lungs of the foals. Therefore, the expression of CD9, SP-A and SP-D in foal lungs was examined. Results: Lungs from one day old (n = 6) and 30 days old (n = 5) foals were examined for the expression of CD9, SP-A, and SP-D with immunohistology and Western blots. Western blot data showed significant increase in the...
Möstl E.In the pregnant mare two different groups of oestrogens are produced by the placenta. The precursor of "classical" oestrogens (oestrone, oestradiol-17 beta and oestradiol-17 alpha) is dehydroepiandrosterone which originates from the fetal gonads. The ring B unsaturated oestrogens (equilin and equilenin and their derivatives) derive from farnesyl pyrophosphate by a pathway not involving cholesterol.
Harrison IW, Speirs VC, Braund KG, Steiss JE.Laryngeal hemiplegia was induced in 4 ponies via a left recurrent laryngeal neurectomy. Reinnervation of the denervated left cricoarytenoideus dorsalis muscle was then attempted using a muscle pedicle graft from the right cricoarytenoideus dorsalis muscle. In 3 ponies there was no return of abductor function and failure of graft survival. In the fourth pony there was return of abductor function along with survival of the muscle bridge, however, there was evidence of reinnervation across the neurectomy site. Muscle-to-muscle neurotization of the paralyzed equine larynx, utilizing the cricoaryte...
Wingfield Digby NJ, Simons MA, Stockman MJ.Various type of insurance policies covering the risks against mortality, economic slaughter and loss of use, breeding failures and payment of veterinary fees are discussed. The role of the veterinary surgeon in supplying certificates of health and in relation to claims, including those involving destruction on humane grounds, are considered.
Furness JB, Poole DP.The functioning of the gastrointestinal tract is under the control of the most extensive system of peripheral neurons in the body, the enteric nervous system, and the largest endocrine system of the body, the GEP endocrine system. The enteric nervous system in large mammals contains 500 million neurons, and the GEP endocrine system produces more than 30 hormones. Numerous enteric neuropathies affecting both humans and animals have been described and digestive disorders affect commercially important species, such as horses and cattle. The most severe enteric neuropathies (e.g., lethal white syn...
Herrera C.Embryo cryopreservation is normally performed with great success in species like humans and cattle. The large size of in vivo-derived equine embryos and the presence of a capsule-impermeable to cryoprotectants-have complicated the use of embryo cryopreservation in equine reproduction. A breakthrough for this technique was obtained when large equine embryos could be successfully cryopreserved after collapsing the blastocoel cavity using a micromanipulation system. High pregnancy rates have been obtained when vitrification is used in combination with embryo collapse.
Spurlock GH.This article deals with the diagnosis and treatment of tendon lacerations. Tendon healing, with its implications relative to treatment, is discussed. The various pros and cons of suturing severed tendons are addressed as well as methods of immobilizing the injured limb. The need for prompt diagnosis and aggressive treatment of tendon sheath injuries is also discussed.