Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Drew B, Barber WP, Williams DG.On a thoroughbred stud four foals were born with greatly enlarged thyroids and leg weakness. Two foals died within 18 hours of birth, the others subsequently recovered. An enlarged thyroid was also evident in one of the resident mares. The thyroids from the dead foals were hyperplastic. Feed analyses showed that the mares had an iodine intake of about 83 mg daily, 8-8 ppm of the dietary dry matter, due almost entirely to the high iodine content of a proprietary compound horse nut which had been fed at the daily rate of 12 lb per head. It was concluded from the histology of the thyroids, the hi...
Hall LW, Trim CM.Horses breathing spontaneously under halothane anaesthesia were subjected to expiratory resistance by the introduction of a water-trap into the expiratory limb of a circle absorber. Resistances of 10 and 20 cm H2O produced no significant increase in PaO2 (P greater than 0.05) during halothane/air and halothane/oxygen anaesthesia. The imposition of resistance was associated with an increase in PaCO2 and a significant increase in mixed venous PCO2. In three animals subjected to 20 cm H2O resistance under halothane/air anaesthesia, the cardiac output was reduced (P less than 0.01). It was conclud...
Pauli B, Althaus S, Von Tscharner C.Migrating fourth-stage larvae of Strongylus vulgaris, a parasite of equines, damage the intima of the anterior mesenteric artery and its larger branches and induce thrombus formation on the injured sites. As the time of larval passage through each of these branches has been exactly determined in earlier experiments, the aim of the present studies is to contribute to a more complete understanding of repair mechanisms in the process of time after thrombotic vascular injuries. Methods: five foals were separated individually to specially cleaned stables and given anthelmintic treatment till the ag...
Ogbourne CP.Studies on the epidemiology of Strongylus vulgaris infection of the
horse. International Journalfor Parasitology 5: 423426. Observations are reported on the size and age
structure of Stronglyus vulguris populations recovered from the anterior mesenteric artery and its
main branches of horses slaughtered at regular intervals throughout a year. Marked seasonal variations were found in the mean monthly numbers of worms present. During spring/early summer the
numbers were relatively low and a large proportion of the arteries had no worms in them at all.
Thereafter, the arterial worm burdens q...
Oxender WD, Noden PA, Bolenbaugh DL, Hafs HD.To determine the minimal effective dose of prostagiandin (PGF2alpha; tromethamine salt) given subcutaneously (SC), mares of mixed breeding (400 kg av body weight) were given 2-, 3-, 5-, and 10-mg doses from 7 to 9 days after ovulation. In some but not all mares given doses of 2 and 3 mg of PGF2alpha, luteolysis occurred, but doses of 5 or 10 mg of PGF2alpha were luteolytic in all mares. The 10-mg dose of PGF2alpha did not cause luteolysis in mares 1 day after ovulation, and caused luteolysis in only 2 of 5 mares on day 3 after ovulation. The same dose of PGF2alpha, however, caused luteolysis i...
Stalheim OH, Gallagher JE, Deyoe BL.The luminal surface topography of bovine, equine, porcine, and caprine uterine tubes was studied by scanning electron microscopy. The main types of epithelial cells were secretory and ciliated. Both types were more active during estrus. Cilia were observed in both the infundibular and the ampular parts of the uterine tube, but ciliated cells were more numerous than secretory cells on the surface of the fimbriae. Sperm were observed in the ampulla of the uterine tube of the cow 2 hours after artificial insemination.
Robinson NE, Dabney JM, Weidner WJ, Jones GA, Scott JB.The digital circulation was isolated in 12 ponies under pentobarbital anesthesia. Blood flow was either controlled by a pump or measured under natural perfusion. The responses to rapid changes and stoppages of blood flow indicated no evidence of autoregulation or reactive hyperemia. Local administration of acetylcholine, histamine, and prostaglandins E1 and E2 decreased prevenous resistance, whereas epinephrine and serotonin caused prevenous constriction. Large doses of epinephrine and serotonin decreased venous caliber. The effects of prostaglandins A1 and F2alpha were variable. The equine di...
Hall LW, Nigam JM.Central venous pressure measurements were made in 74 horses and ponies free from clinical evidence of cardiopulmonary disease. Using the sternal manubrium as the zero reference point, the mean value obtained was 12 cm H2O (S.D. +/- 6). There was a significant correlation with body weight (r=0.6, p less than 0.001) but there was none with age, sex, breed or type. During halothane anaesthesia, using the same reference point, the mean value was 24.5 cm H2O (S.D. +/- 6) in 28 animals in right lateral recumbency, 29 cm H2O (S.D. +/- 8) in 17 animals in left lateral recumbency and -6 cm H20 (S.D. +/...
Ishitani K, Listowsky I.Horse spleen ferritin was fractionated into its constituent isoferritins by isoelectric focusing. Separated isoferritins were stable and showed no tendency to redistribute when re-examined by analytical gel focusing. All of the isoferritins were immunologically indistinguishable when tested with antibodies raised against unfractionated horse spleen ferritin. The separated isoferritins also had similar conformations as determined by circular dichroism. Iron distribution studies, however, revealed a wide disparity among the isoferritins. The most acidic components had the lowest iron content but...
Stickle RL, Erb RE, Fessler JF, Runnels LJ.Unilateral ovariectomy was performed on 3 mares affected with granulosa cell tumors. Tumor fluid in each mare was found to contain estrogen, testosterone, and progesterone. In 2 mares, preoperative blood plasma concentrations of these hormones were comparable to those of a series of clinically normal mares. The other mare, which had a history of aggressive, masculine behavior, had higher testosterone content in the tumor fluid and in the preoperative blood sample. After surgical removal of the tumors, each mare developed follicles and ovulated with the remaining ovary. Each was eventually bred...
Lokhorst HM, Breukink HJ.Two cases of Auto-immune hemolytic anemia (AHA) in the horse are described. The pathogenesis of AHA in man is related to the findings in the horses. Besides from routine hematological and biochemical investigations specific data were obtained from the erythrocyte osmotic fragility test, the Coombs test, the serum haptoglobulin level and the cold agglutinin test. The first patient, a six month old Dutch standardbred colt, probably suffered from an acute attack of cold-induced hemoglobinuria with severe anemia and acronecrosis of the tops of both ears and of several parts of the skin that had be...
Clarke CJ, Roeder PL, Dixon PM.A severe, advanced case of nutritional osteodystrophia fibrosa is described in a 10-year-old gelding with primary upper respiratory obstruction and chronic weight loss, which was one of a group of similarly affected horses in Ethiopia. The diagnosis was based on the clinical signs, gross lesions, histopathology and management history. The affected bones had suffered severe mineral depletion.
Hauspie S, Martens A, Declercq J, Busoni V, Vanderperren K, van Bree H, Saunders JH.To describe the radiographic appearance of the dorsoproximal aspect of the sagittal ridge of the third metacarpal/metatarsal bone in Warmblood horses. Methods: The lateromedial radiographic projections of the metacarpo-/metatarsophalangeal joints performed on horses as a part of stallion selection were used. The dorsal aspect of the distal third metacarpal/metatarsal bone was divided in two areas. The appearance of the bone surface in area I was classified as normal, irregular, notch, indentation and lucency. For area II, the categories were normal, irregular, depression or lucency and flatten...
Muttini A, Petrizzi L, Tinti A, Bertoluzza A.An investigation was carried out on most common synovial fluid parameters of normal and osteochondritic hocks of horses less than 12 months old in order to confirm the presence of an inflammatory process. Furthermore, a spectroscopic study was performed on synovial fluid from both normal and diseased hocks. A depolymerization of hyaluronic acid was demonstrated in synovial fluid from diseases joints, similar to that reported in human rheumatoid arthritis. A one month rest seem to normalize all parameters considered and in one joint, a return to normal infrared spectrum was demonstrated.
Mitchell C, Riley CB.Humeral fractures are rare and usually carry a guarded prognosis in adult horses. This paper describes the evaluation and the successful surgical management of a fracture of the lateral supracondyloid crest and part of the epicondyle of the humerus in an adult quarter horse.
Smith RF, Jackson LS, Moore A.An 125I radioimmunoassay to determine the pattern of urinary excretion of etorphine (a semisynthetic opiate agonist) after its administration to horses is described. Three thoroughbred horses were each given 5, 15, 30 and 100 micrograms of etorphine intramuscularly. Urine was collected for up to 72 after administration. The maximum etorphine concentration after administration of a dose of 5 micrograms was 711 pg ml-1 (concentrations were greater than 100 pg ml-1 after 23 h in all three horses); a 15 micrograms gave 2661 pg ml-1 (levels remained above 100 pg ml-1 for more than 44 h in each hors...
Dyson S.The carpus and metacarpus of 40 horses which were free from lameness and 40 horses with lameness associated with the metacarpophalangeal joint or more distal limb were examined radiographically (Group A). The opacity of the proximal third of the third metacarpal bone was regular, with a uniform trabecular pattern. Osseous cyst-like lesions (OCLLs) were identified in the radial carpal bone (1), the ulnar carpal bone (2), the second carpal bone (15) and the fourth carpal bone (1). Thirty-one of 638 horses (4.8 percent) with forelimb lameness had pain localised to the proximal metacarpal region u...
da Silva TRO, Gonçalves PNC, Marcus VB, Mucellini CI, Dos Santos IR, Kommers G, Driemeier D, Flores EF, Cargnelutti JF, Flores MM.For approximately one decade, a novel papillomavirus termed Equus caballus papillomavirus-2 (EcPV-2) has been associated with equine penile/preputial papillomas and squamous cell carcinomas (SCCs). It is currently believed that the virus has a carcinogenic activity, being able to induce such neoplastic lesions. After being first described, EcPV-2 has been detected in many countries from North America, Europe, and Asia; however, to date, it has not been reported in Brazil. The aim of this research was to investigate the presence of EcPV-2 in penile/preputial papillomas and SCCs of Brazilian hor...
Guthrie AJ, Nichas E, Viljoen FV, Hartmann AM, Killeen VM.A case of sustained supraventricular tachycardia of unknown aetiology in a two-year-old Thoroughbred filly is reported. The cardiac dysrhythm was successfully treated by the oral administration of quinidine sulphate. Conversion of the dysrhythm to sinus rhythm occurred approximately 80 min after the initial dose of 5 g of quinidine sulphate. The horse returned to training approximately 2 months after treatment and has since successfully returned to racing.
French jockeys suffer more severe injuries when they fall off their horses than their British counterparts. While it has been shown that jockeys suffer high rates of fatal and non-fatal injuries, little is known about differences in injury rates between countries. To investigate this, researchers from Australia, France and the UK used prospectively collected data on the rates of fatal and non-fatal injuries in flat and jump jockeys in France and compared them with data from the UK.
Kirker-Head CA, Kerwin PJ, Steckel RR, Rubin CT.Liquid metal strain gauges (LMSG) were implanted surgically at three locations on the intact linea alba (LA) in eight horses. LA strain, strain rate, change in strain and stress were recorded during general anaesthesia, recovery from anaesthesia, standing, vocalisation, rectal palpation and at the walk, trot and canter. LA stress was quantitated using an in vitro tensiometric technique. Stress-strain responses differed significantly (P < 0.05) with location, but each described a characteristic relationship for viscoelastic tissues. Maximum peak stress, peak strain and change in strain occurred...
Raz T, Carley S, Card C.The objective was to compare the effects of eFSH and deslorelin treatment regimes on ovarian stimulation and embryo production of donor mares in early spring transition. Starting January 30th, mares kept under ambient light were examined by transrectal ultrasonography. When a follicle > or =25 mm was detected, mares were assigned to one of two treatment groups, using a sequential alternating treatment design. In the eFSH group, mares (n=18) were treated twice daily with eFSH (12.5mg im) until they achieved a follicle > or =35 mm; hCG was given 36 h later. In the deslorelin group, mares (n=18) ...
Brown J, Physick-Sheard P, Greer A, Poljak Z.Horse movements are one of the most important factors for the spread of equine diseases, and past epidemics indicate that contact networks play an important role. Network analysis was used to describe the spatial and temporal characteristics of horse movements between Standardbred racetracks in Canada and the United States during 2019, and to characterize the network to provide a better understanding of the potential racetrack-to-racetrack spread of infectious disease within the network. Networks were constructed and analyzed as an overall network (the entire study period) and monthly networks...
Dehennin L, Bonnaire Y, Plou P.The dietary supplements 19-norandrostenedione and 19-norandrostenediol are potential metabolic precursors of nandrolone. They are considered by law in the United States as prohormones without proven therapeutic, curative or diagnostic properties, and therefore available as over-the-counter drugs. Oral dosages of 0.1-1 mg/kg body weight were readily absorbed in the equine intestinal tract and thereby led to urinary excretion of drastically increased 5alpha-estrane-3beta,17alpha-diol conjugates, which are known to be final metabolites of nandrolone. The actual rules for detection of illicit nand...
Ekfalck A, Jones B, Obel N.After a survey of the state of laminitis research the authors conclude that none of the present concepts of the pathogenesis of laminitis unequivocally explains the basic clinical and morphological observations in this disease. There is therefore reason to consider the advances that have been made during the last decades in respect to the influence of various substances on the differentiation of cultured skin keratinocytes. The technique is available for studying hoof keratinocytes in a comparable way. Relevant literature on cultured skin keratinocytes is surveyed. Some of the results from exp...
Ishiyama T, Nishimori T, Kato M, Yamada H, Sato K, Sentsui H.Restriction endonuclease analysis of equine herpesviruses 1 (EHV-1) and 4 has been investigated using cultured cells infected with these viruses. The DNA cleavage patterns of these viruses were observed in the intracellular DNA after digestion with Eco RI and electrophoresis. This procedure was applied to the diagnosis of equine herpesvirus infection in aborted equine fetuses. The characteristic Eco RI restriction pattern of EHV-1 DNA was directly detectable in the emulsion of lungs collected from aborted equine fetuses.
