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Topic:Veterinary Medicine
Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Gastrointestinal stromal tumors in equids. Eleven gastrointestinal neoplasms from 10 aged horses and 1 pony were examined grossly, his tologically, immunohistochemically, and (in two cases) ultrastructurally. Clinical signs were associated with two neoplasms, and the other nine tumors were incidental findings at laparotomy or necropsy. The neoplasms were solitary (9/11) or multifocal (2/11), well demarcated, serosal or mural masses of stomach (1), jejunum (1), ileum (3), cecum (5), and/or colon (2). Microscopic examination revealed discrete spindle cells arranged in compact patterns with fascicles and whorls or cribriform pattern with ...
Point mutation of neu oncogene in animal peripheral nerve sheath tumors. Thirty-four peripheral nerve sheath tumors of four domesticated animal species were characterized and assayed for point mutation of the neu oncogene. Based on their morphoimmunophenotype, 32 tumors were classified as schwannomas. Schwannoma morphology was characterized by the presence of Antoni type A and B pattern and immunoreactivity for S-100 protein and vimentin. Two anaplastic and metastatic tumors originating from spinal cord root, immunonegative for S-100 protein and positive for vimentin, were classified as malignant peripheral nerve sheath tumors (MPNSTs). Four malignant schwannomas a...
Characterisation of tryptase and a granzyme H-like chymase isolated from equine mastocytoma tissue. Mast cell proteinases are important inflammatory mediators in man and other species, but until now there has been no investigation of the nature of equine mast cell proteinases. These studies describe the purification and characterisation of two proteolytic components from equine mastocytoma tissue, detected using chromogenic substrates for trypsin and chymotrypsin. Following chromatographic purification, the trypsin-like component was found to be equine mast cell tryptase by N-terminal amino acid sequencing, showing a close similarity with human tryptase-beta (85% identity over 20 residues). ...
Elevated extrahepatic expression and secretion of mammary-associated serum amyloid A 3 (M-SAA3) into colostrum. Mammary-associated serum amyloid A 3 (M-SAA3) was secreted at highly elevated levels in bovine, equine and ovine colostrum and found at lower levels in milk 4 days postparturition. N-terminal sequencing of the mature M-SAA3 protein from all the three species revealed a conserved four amino acid motif (TFLK) within the first eight residues. This motif has not been reported to be present in any of the hepatically-produced acute phase SAA (A-SAA) isoforms. Cloning of the bovine M-Saa3 cDNA from mammary gland epithelial cells revealed an open reading frame that encoded a precursor protein of 131 a...
Feeding practices associated with colic in horses. To determine whether specific feeding practices were associated with development of colic in horses. Methods: Prospective matched case-control study. Methods: 364 horses examined by veterinarians in private practice in Texas because of colic (cases; n = 182) or any other reason (controls; 182). Methods: Participating veterinarians were sent forms at the beginning of the study to collect information on signalment, feeding management practices, farm management practices, and preventive medical treatments. Case and control horses were compared by use of conditional logistic regression to identify...
Description of ciliary body anatomy and identification of sites for transscleral cyclophotocoagulation in the equine eye. To determine the most appropriate anatomical location for diode laser probe placement to accurately photoablate the equine ciliary body using a contact, transscleral approach. Methods: Original research. Methods: Forty-two freshly enucleated adult equine eyes were evaluated. The horizontal, medial vertical, central vertical, and lateral vertical lengths of the cornea were measured from limbus to limbus. Needles were inserted perpendicular to the sclera at specific distances posterior to the external limbus at the 1, 2, 4, 5, 6, 7, 8, 10, 11 and 12 o'clock positions. The per cent frequency that...
Three-dimensional kinematics of the proximal interphalangeal joint: effects of raising the heels or the toe. The proximal interphalangeal joint (PIPJ) has always been considered as a low-motion joint with an almost constant angle during loading of the limb. Until very recently, its motion was not taken into account in kinematic studies in vivo. Recent in vivo studies yielded surprisingly high ranges of motion in this joint. The aim of this study was to measure, in terms of the 3 possible rotations (flexion/extension, collateromotion and axial rotation), the movements of the PIPJ in vitro during limb loading in a neutral position (500-6000 N) and after the addition of heel and toe wedges (6 degrees an...
Locomotion evaluation for racing in thoroughbreds. The potential racing and locomotory profile of a Thoroughbred yearling should be taken into account for its training programme and racing career. A gait test has been designed to assist the trainer in this task. The aim of this study was to investigate the temporal and kinetic locomotory variables of Thoroughbreds at the gallop, in relationship to their racing ability. Thirty Thoroughbred horses in race training were tested at maximal speed during a training session. The training exercise consisted of a warming-up session at trot and canter for 10 min followed by a gallop session at increasing...
Forelimb tendon loading during jump landings and the influence of fence height. Lameness in athletic horses is often caused by forelimb tendon injuries, especially in the interosseus tendon (TI) and superficial digital flexor tendon (SDF), but also in the accessory ligament (AL) of the deep digital flexor tendon (DDF). In an attempt to explain the aetiology of these injuries, the present study investigated the loading of the tendons during landing after a jump. In jumping horses, the highest forces can be expected in the trailing limb during landing. Therefore, landing kinematics and ground reaction forces of the trailing forelimb were measured from 6 horses jumping singl...
Normal three-dimensional behaviour of the metacarpophalangeal joint and the effect of uneven foot bearing. The purpose of this study was to quantify small amplitude rotational movements in the metacarpophalangeal joint (MPJ) of the horse and to measure the influence of asymmetric placement of the foot on these articular angles. Trihedrons, supporting kinematic markers defining a local frame, were screwed into the third metacarpal bone and the proximal phalanx of 4 isolated forelimbs. The limbs were loaded in a press, and the lateral or medial aspects of the foot were raised alternately by a 12 degrees wedge. The use of the joint coordinate system permitted the simultaneous and continuous computing ...
Kinematic analysis of the symmetry of limb movements in lame trotting horses. This study was undertaken to describe the symmetry of movements of fore- and hindlimbs in horses suffering from various spontaneous lamenesses. Two groups of horses were studied: 13 clinically sound horses and 24 lame horses. Using a 3-dimensional (3-D) kinematic analysis system, movements of both sides of each horse were recorded simultaneously while trotting on a track. The differences in motion between left and right homologous joints of each horse were quantified using symmetry indices based on an intercorrelation method. Symmetry indices obtained for each lame horse were then compared wit...
Evaluation of the EMG activity of the long back muscle during induced back movements at stance. In this study we investigated the activity of the main back muscle (Musculus longissimus) by surface electromyography (EMG) during induced extension and lateral flexion at stance. Measurements were taken of 15 horses (age 5-20 years, 450-700 kg bwt) without signs of back pain. Reflecting markers were placed on the head, spinous processes of T5, T12, T16, L3 and on 2 of the sacral bones. The surface EMG electrodes were situated on the Musculus longissimus on both sides of the dorsal spinous processes of T12, T16 and L3. In all horses and all movements (extension, lateral flexion to the left and...
Range of back movement at trot in horses without back pain. The aim of this study was to establish basic reference data for evaluating 3-dimensional movement of the equine back at the trot. In 22 mature horses without any clinical signs of back pain, the movement of the back was measured during trotting on a treadmill with a system for motion analysis. The position of the markers placed on the head, hooves, skin above the spinous processes of T5, T10, T16, L3 and on 2 of the sacral spines was recorded. The results of all movements were expressed in percent of the horse's height at its withers. At the trot, the maximum lateral movement at the head was 1...
Listeria keratitis in a horse. Listeria monocytogenes is ubiquitous in the environment but is rarely reported as a cause of keratitis in animals. In this case, a mare was presented with epiphora and evidence of pain in the right eye. Listeria monocytogenes was isolated from a corneal lesion, and bacteria were also seen in the cytologic evaluation. This is the first reported case of ulcerative keratitis associated with L. monocytogenes in a horse.
Finite element analysis (FEA) as a model to predict effects of farriery on the equine hoof. A finite element (FE) hoof capsule was built as a small, symmetrical forelimb hoof on IDEAS* as a model for calculation and visualisation of stress and displacement of the equine hoof capsule. The model's loading was performed according to the suspension of the coffin bone within the hoof wall (pulling force) and over the sole and frog (compressing force) with a total of 3000 N. Restraints of the model's ground nodes and surface wall nodes were defined for simulation of 4 shoeing situations: a regular horseshoe, a horseshoe with a toe clip, a horseshoe with regular side clips and a horseshoe w...
Body centre of mass movement in the lame horse. The body centre of mass (BCM) is a key factor in the analysis of equine gait, as its position and movement determines the distribution and magnitude of loads on the limbs. Changes in the BCM movement are proposed to be important factors in the lameness management of horses. In this study, changes in the position and the 3-dimensional (3-D) movement of the BCM in horses with induced forelimb lameness were studied using a kinematic, segmental method. The kinematics of 30 markers representing 20 body segments were recorded in 12 horses while trotting (3.9 m/s) on a treadmill using a high speed vi...
Assessment of gait irregularities in the horse: eye vs. gait analysis. The purpose of this study was to verify the sensitivity of 2 gait analysis methods in detecting subtle lameness and to compare the results to the traditional orthopaedic evaluation. Twenty-two horses were evaluated (1) subjectively by 3 different experienced clinicians and (2) objectively with synchronised ground reaction force and accelerometric gait measurements on a treadmill. The horses were assigned for each of the 3 methods independently to one of 3 groups (GR): sound, lameness front limb, lameness hindlimb. Additionally, for each horse, the affected limb (AL) and degree of lameness (DL)...
Effects of heel and toe elevation upon the digital joint angles in the standing horse. Five sound mature horses, age 8-14 years, with toe angles 45.5-55.0 degrees were placed on a specially designed platform with only the left forelimb weightbearing, which allowed the successive production of 7 different conditions of foot orientation: neutral position (N), 5, 10, 15 degrees heel (H5, H10, H15) and toe (T5, T10, T15) elevation, performed according to 2 different sequences. For each condition, 2 lateromedial radiographs were taken to evaluate the metacarpophalangeal joint (MPJ) and both interphalangeal joint (PIPJ and DIPJ) angles, respectively. In addition, two-dimensional (2-D)...
Enterotoxigenic potential of Staphylococcus intermedius. Staphylococcal food poisoning (SFP) caused by enterotoxigenic staphylococci is one of the main food-borne diseases. In contrast to Staphylococcus aureus, a systematic screening for the enterotoxins has not yet been performed on the genomic level for the coagulase-positive species S. intermedius. Therefore, the enterotoxigenic potential of 281 different veterinary (canine, n = 247; equine, n = 23; feline, n = 9; other, n = 2) and 11 human isolates of S. intermedius was tested by using a multiplex PCR DNA-enzyme immunoassay system targeting the staphylococcal enterotoxin genes sea, seb, sec, sed...
Changes due to age in the kinematics of trotting Andalusian foals. The purpose of this study was to evaluate the effect of growth on biokinematic characteristics at the trot in a group of 9 Andalusian foals from age 12 to 36 months in order to identify which stride variables change or remain invariable. Biokinematic analysis was performed by using a computer-assisted videography system (25 Hz frame rate). An increase in stride length as well as the fore- and hindlimb stride duration was found. A tendency to increase flexion of the shoulder, elbow and carpal joints was observed while the forelimb fetlock increased its maximal extension. In the hindlimb, most o...
Predominance of G3B and G14 equine group A rotaviruses of a single VP4 serotype in Japan. A total of 65 equine group A rotaviruses (GAR) isolated from diarrheal foals at 48 farms in Hokkaido, Japan, between 1996 (29 isolates) and 1997 (36 isolates) were characterized for their VP7 and VP4 serotypes by PCR, nucleotide sequencing, and virus neutralization (VN) tests. By PCR VP7 typing, all isolates were classified as G3 or G 14, and the predominant serotype in each year was G3 (86%) in 1996 and G14 (53%) in 1997. VN tests with these 20 isolates randomly selected confirmed the specificity of PCR on the bases of complete agreement of the results in these methods (9 G3 and 11 G14), and ...
Analysis of a radiographic technique for measurement of equine metacarpal bone shape. Accuracy and limitations of a radiographic technique were established for measurement of metacarpal bone shape in horses. A radiographic index (RI) has been used to measure changes in third metacarpal (Mc3) bone shape in response to training in young racehorses. The aim of these experiments was to determine the effects of positioning of the radiographic equipment on RI measurements from lateromedial radiographs of a left ex vivo metacarpus. Repeatability of the RI measurement in left lateromedial and right mediolateral view Mc3s were evaluated. The width of the dorsal cortex (DC), palmar corte...
Effects of age and recombinant equine somatotropin (eST) administration on immune function in female horses. Aging has been associated with declines in somatotropin and IGF-I levels as well as declines in immune function. To determine the effects of age and whether ST administration could reverse immunosenescence in horses, eight young and eight aged female standardbred horses were given 10 mg/d recombinant equine somatotropin (eST) or vehicle buffer for 49 d. Plasma IGF-I concentrations in both age groups were higher in eST-treated animals (P < 0.001), and higher in young eST-treated mares than in aged eST-treated mares during wk 4 to 7 (P < 0.001). There was a trend toward lower monocyte and ...
Effects of treadmill speed on the mechanics of the back in the trotting saddlehorse. Speed related changes in trunk mechanics have not yet been investigated, although high-speed training is currently used in the horse. To evaluate the effects of speed on back kinematics and trunk muscles activity, 4 saddle horses were recorded while trotting on a horizontal treadmill at speeds ranging from 3.5 to 6 m/s. The 3-dimensional (3-D) trajectories of skin markers on the left side of the horse and the dorsal midline of the trunk were established. Electrical activity was simultaneously obtained from the longissimus dorsi (LD) and rectus abdominis (RA) muscles using surface electrodes. T...
Segmental in vivo vertebral kinematics at the walk, trot and canter: a preliminary study. Understanding the pathophysiology of equine back problems, for clinical evaluation, treatment or injury prevention, requires understanding of the normal 3-dimensional motion characteristics of the vertebral column. Recent studies have investigated regional vertebral kinematics; however, there are no reported measures of direct in vivo segmental vertebral kinematics in exercising horses. Relative movements between 2 adjacent vertebrae were recorded for 3 horses that were clinically sound and did not have a known history of a back problem. A transducer consisting of 2 fixtures and an array of li...
Quantification of hoof deformation using optical motion capture. Deformation of the hoof capsule occurs during stance phase as a result of loading by the distal phalanx. The objective of this study was to evaluate optical motion capture as a technique for measuring hoof deformation during locomotion, and to quantify the deformation of the dorsal wall during stance phase. The front left feet of 3 clinically sound horses were used for this study. The hoof wall was cleaned and 9 retroreflective markers were glued to the lateral and dorsal hoof wall, and shoe. Each horse was trotted in a straight line at constant speed while marker positions during stance phase...
Measurement of serum amyloid A in the neonatal foal using a latex agglutination immunoturbidimetric assay: determination of the normal range, variation with age and response to disease. This paper describes the use of a latex agglutination assay to measure serum amyloid A (SAA) in the neonatal foal. The normal range and response to clinical disease was determined. This retrospective study evaluated SAA concentrations over the first 3 days postpartum of 226 Thoroughbred foals judged to be clinically healthy. The normal range for each day was determined; levels were found to be significantly highest on Day 2 (Day 1 vs. Day 2 P<0.0001). The 95th percentile for Days 1-3 was 27.1 mg/l. Clinical records of 133 foals, presented as first or second opinion cases, were evaluated. Fo...
Application of a constant blood withdrawal method in equine exercise physiology studies. The aim of the present study was to test a constant blood withdrawal method (CBWM) to collect blood samples from horses during treadmill exercise. CBWM was performed in 4 Standardbreds and 5 Haflinger horses. A peristaltic pump was used to control blood aspiration from an i.v. catheter via an extension line. Blood was collected using an automatic fractions collector, with a constant delay time between the drawing of blood and sample collection. Blood withdrawal using CBWM was made during a treadmill standardised exercise test (SET). A blood flow of 12 m/min was used and samples collected every...
Effects of an external nasal strip and frusemide on pulmonary haemorrhage in Thoroughbreds following high-intensity exercise. The purpose of this study was to examine the effects of an external nasal strip (NS), frusemide (FR) and a combination of the 2 treatments (NS + FR) on exercise-induced pulmonary haemorrhage (EIPH) in Thoroughbred horses. It was hypothesised that both the NS and FR would attenuate EIPH as assessed by red blood cell count in bronchoalveolar lavage fluid. In random order, 8 horses completed each of 4 sprint exercise tests on a treadmill: 1) NS; 2) FR (0.5 mg/kg bwt i.v., 4 h pre-exercise); 3) NS + FR; and 4) control (C; no treatment). After a 5 min warm-up (4.5 m/s), horses completed 2 min runni...
