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Topic:Veterinary Research
Veterinary research in horses encompasses the study of diseases, health management, and medical treatments specific to equine species. This field investigates various aspects of horse health, including infectious diseases, metabolic disorders, and musculoskeletal conditions. Researchers focus on understanding the pathophysiology of equine ailments, developing diagnostic tools, and evaluating therapeutic interventions. The study of horse health also involves examining preventive measures such as vaccination protocols and nutritional management to promote overall well-being. This page collects peer-reviewed research studies and scholarly articles that explore the diverse areas of veterinary science related to horses, providing insights into disease mechanisms, treatment strategies, and advancements in equine healthcare.
Comparison of the lipoprotein profiles obtained from rat, bovine, horse, dog, rabbit and pig serum by a new two-step ultracentrifugal gradient procedure. A new two-step gradient technique has been used in the separation of the different classes of lipoproteins from the serum of cows, horses, dogs, pigs, rabbits and rats. Total lipoproteins were first isolated at d 1.21 then floated through a d 1.006 to d 1.21 gradient. Collection by mean of a gradient fractionator provided directly comparable lipoprotein profiles, allowed the determination of the exact density range of each lipoprotein class and the fraction by fraction analysis of composition. Cholesterol and apo AI recoveries were high. Horse, dog, rabbit and pig exhibited three distinct lipo...
Blind-end atresia coli in two foals. Blind-end atresia coli was observed in two genetically unrelated foals at about the same time and location. The two foals, one an Appaloosa and the other a Quarterhorse, were born 4 days apart on nearby but separate farms. The Appaloosa foal died after surgical anastomosis of the affected segments of the colon. The Quarterhorse foal was euthanized after the defect was found at laparotomy. Both foals were necropsied and representative tissues were examined histopathologically. Histopathologic results were unremarkable. No cause of the defects could be determined and the timing and geographical ...
Increased acidophilia of eosinophil granules after EDTA treatment. The acidophilic reaction of eosinophil leucocyte granules from human, pig and horse blood smears was investigated by using May-Grรผnwald-Giemsa staining after previous treatment with EDTA and sodium citrate solutions. The same peak at 530 nm, but absorption values considerably higher than those of controls, were found in eosinophil granules after application of chelating agents, indicating that removal of metal cations could unmask basic groups in these structures.
Dynamic model of the equine hindlimb during the swing phase. A dynamic model is developed to describe the swing phase of the hindlimb of a normally walking horse. The limb was represented by four rigid segments constrained to move in a sagittal plane only. The mathematical equations of motion of this four-element pendulum were formulated using Lagrange's theorem. The morphometric parameters from the hindlimb segments of 3 horses were determined using high-speed film analysis. Five muscle groups were incorporated in the model. Muscle activity was derived from earlier EMG measurements. Optimization of muscle moments resulted in a simulated swing movement ...
Opiate-like and adrenocorticotrophin-like materials in equine pancreas. Equine pancreatic acetone powder was extracted with an acetone-water-HCl mixture. An acid acetone powder resulted by adding a copious volume of acetone to the extract. The powder was subjected to salt fractionation, gel filtration and chromatography on CM-cellulose. Steroidogenic activity, ACTH-like immunoreactivity and opiate receptor binding activity were distributed among the CM-cellulose chromatographic fractions derived from material unretarded as well as from material retarded on Sephadex G-25. The data indicates a separation of steroidogenic and opiate receptor binding activities, and t...
Preparation of Clostridium septicum antigen for hyperimmunization of horses using a dialyzed culture. The preparation of toxic cultures of Clostridium septicum is described, using an apparatus with a straight dialysis tubing, where the medium is filled both into the nutrition and cultivation space of the apparatus. Using the cultivation to nutrition volume rate 1:2, mean titre of lethal antigen in filtrates 3.86 limes mortis per mL and 300 dosis lethalis minima per Lm was obtained in comparison with the values of 2.22 and 150 respectively in flask filtrates. Native filtrates of dialyzed cultures were better antigens for hyperimmunization of horses than the culture filtrates from flasks.
Antistreptolysin O titer in horses. Antistreptolysin O (ASO) titers were determined in the sera of 532 horses from stud farms and 436 working horses from small farms. A statistically significant correlation was seen between the ASO titer and the age of the horses. There was a significant difference between mean ASO titer in horses 0-2 years and horses 2-10 years In horses older than 10 years the titer was significantly higher than mean ASO titer for the group. Twenty four of 30 horses in which ASO titer was higher or equal to 80 I.U. had histories which suggested that streptococcal infection had occurred. Clinical and bacteriolo...
[Structure and topography of the nucleus proprius cornus dorsalis of the spinal cord of horses]. The studies performed on spinal cords of two horses revealed that cells of the nucleus of the own dorsal horn are present in all segments of lumbo-sacral part of the spinal cord. The nucleus is composed of two parts: basal and marginal. Basal part is composed of large and medium size cells situated in 2/3 of the lower part of the grey substance of the dorsal horn. The marginal part of the described nucleus is composed of elongated and spindle shaped cells situated along the dorsal margine of the grey substance of the dorsal horn. Continuity of the nucleus in lumbo-sacral part of the spinal cor...
Comparison of antiproteolytic activities of alpha-1-proteinase inhibitors from the plasma of some mammalian species. Alpha-1-proteinase inhibitors isolated from plasmas of horse, ox, pig, rabbit and man were used for determination of some kinetic parameters of interaction with three horse leucocyte proteinases and bovine pancreatic trypsin and chymotrypsin. Effective molar ratio of enzyme-to-inhibitor, inactivation rate constant and inhibition constant were measured. In horse, ox, pig and rabbit two principal electrophoretic forms of alpha 1-PI could be distinguished. Both forms effectively inhibited trypsin but usually only one form reacted promptly and stoichiometrically with chymotrypsin and leucocyte ela...
[14C]monensin balance in bile-fistulated ponies. To measure absorption of monensin or its metabolites and its elimination from the body, [14C]monensin sodium was given orally (1 mg/kg body wt) to two bile-fistulated ponies and iv (8.7 mg) to one bile-fistulated pony. For one orally-dosed pony, 4.7% of the 14C was eliminated in bile, 52% in feces, .7% in urine and 33% remained in the gastrointestinal (GI) tract after 3 d. Total 14C recovery was 90%. For the other orally-dosed pony, 18.3% of the 14C was eliminated in bile, 69% in feces, 1.7% in urine and 7% remained in the GI tract after 4 d. Total 14C recovery was 98%. For the iv-dosed pony, ...
XY sex-reversal syndrome in the domestic horse. The XY sex-reversal syndrome occurs when a phenotypic mare is born that has the karyotype of a stallion. The syndrome is manifested by both genotypic and phenotypic heterogeneity. The sex-reversed genetic condition occurs frequently within certain pedigrees where XY females have been found and can be readily detected by chromosome karyotyping. The phenotypic spectrum ranges from the feminine mare with a reproductive tract that is within normal limits to the greatly masculinized mare. Pedigree analysis suggests that there are two modes of inheritance: (1) an X-linked recessive or autosomal sex-...
Annual cycle of the Sertoli cell population in adult stallions. Stereological methods were employed in two experiments with adult stallions: to confirm seasonal variation in number of Sertoli cells and to characterize the annual cycle of the Sertoli cell population. In the first experiment, testes from 28 adult (4-20 years old) horses obtained in the non-breeding season (December-January) were compared to testes from 28 adult horses in the breeding season (June-July). Sertoli cell numbers were calculated from the nuclear volume density, parenchymal volume, and volume of an individual Sertoli cell nucleus determined by reconstruction of serial sections or f...
An experimental study of the healing process of equine chondral and osteochondral defects. Four full thickness cartilage defects, two linear and two elliptical, and four subchondral cavity defects were created at the point of weightbearing of the medial femoral condyle in four experimental ponies. This study showed that subchondral bone cysts can develop following full thickness (cartilage only) linear cartilage defects at a weightbearing location. Subchondral bone cysts did not develop following the removal of an elliptical piece of cartilage, exposing the subchondral bone. Primary subchondral defects created in communication with the joint cavity did not heal by replacement with b...
Polymorphic restriction sites in the horse beta-globin gene cluster. Horse DNA samples digested with PstI and probed with the rabbit beta 1 globin gene show three phenotypes determined by one fragment of variable length (about 5.1 or 3.3 kb). Family data demonstrate that these fragments segregate as Mendelian alleles. The frequencies of the two alleles are 0.66 for the 3.3-kb fragment and 0.34 for the 5.1-kb one. Another polymorphism has been detected with BamHI. Again three phenotypes determined by two alleles (fragments of 7.5 and 3.8 kb) have been observed. Allelic frequencies of the 7.5- and 3.8-kb fragments are 0.24 and 0.76 respectively. The two polymorph...
Effects of training on muscle composition in horses. Biopsy samples were obtained from the middle gluteal muscle of 10 Thoroughbred horses undergoing a commercial race-training program. Samples were obtained before the program began and again after 6 and 12 weeks of training. All horses had raced at least once by the 12th week of training. Serial sections of muscle were examined histochemically for myosin adenosinetriphosphatase after either acid (pH 4.3 and 4.6) or alkaline (pH 10.3) preincubation, and then muscle fibers were identified as types I, IIA, IIB, or IIC. The oxidative capacity of individual fibers was assessed, using the reduced nic...
Control of strongylosis in horses by alternate grazing of horses and sheep and some other aspects of the epidemiology of Strongylidae infections. Alternate grazing of horses and sheep as a control measure for gastrointestinal helminthiasis was studied in three grazing experiments in 1981, 1982 and 1983. Each year a group of three mare yearling Shetland ponies, which were kept on a small pasture from spring to autumn, were compared with a similar group which grazed a similar or the same pasture until July and were subsequently removed to a similar pasture which had been grazed by sheep from April to July. In addition both groups were treated with an anthelmintic when the latter group was removed to the sheep pasture. Pasture larval count...
