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Topic:Veterinary Research

Veterinary research in horses encompasses the study of diseases, health management, and medical treatments specific to equine species. This field investigates various aspects of horse health, including infectious diseases, metabolic disorders, and musculoskeletal conditions. Researchers focus on understanding the pathophysiology of equine ailments, developing diagnostic tools, and evaluating therapeutic interventions. The study of horse health also involves examining preventive measures such as vaccination protocols and nutritional management to promote overall well-being. This page collects peer-reviewed research studies and scholarly articles that explore the diverse areas of veterinary science related to horses, providing insights into disease mechanisms, treatment strategies, and advancements in equine healthcare.
A degenerative joint disease in the horse.
New Zealand veterinary journal    November 1, 1977   Volume 25, Issue 11 321-335 doi: 10.1080/00480169.1977.34445
Wyburn RS.No abstract available
Foot problems in horses.
Modern veterinary practice    November 1, 1977   Volume 58, Issue 11 967-970 
No abstract available
A subunit-sized butyrylcholinesterase present in high concentrations in pooled rabbit serum.
The Biochemical journal    November 1, 1977   Volume 167, Issue 2 367-376 doi: 10.1042/bj1670367
Main AR, McKnelly SC, Burgess-Miller SK.A butyrylcholinesterase of mol.wt. approx. 83000 was observed in pooled rabbit serum. The enzyme was named monomeric butyrylcholinesterase to distinguish it from the larger oligomeric butyrylcholinesterase of horse and human serum whose subunits are the same size as the monomeric enzyme. The active-site concentration of monomeric butyrylcholinesterase in the pooled serum was 0.18mum, which is five times the concentration of butyrylcholinesterase in pooled horse serum. This was surprising, since the horse serum is regarded as a rich source of butyrylcholinesterase, whereas rabbit serum is not g...
Vasculature of the equine and canine iris.
American journal of veterinary research    November 1, 1977   Volume 38, Issue 11 1791-1799 
Anderson BG, Anderson WD.Methyl methacrylic casts were prepared and tissue was freshly collected for histologic examination to compare the vascular supply and the structure of the vessels of the iris in the adult horse with those of the dog. In the horse, ciliary blood vessels divided in the iris and formed a complete major arterial circle of the iris. In the dog, the ciliary blood vessels divided in the ciliary body and, by means of recurrent branches, formed a complete arterial circle. From this circle, radial arteries extended toward the pupillary margin. The radial vessels in the horse were nearly straight and joi...
Erythrocyte rosette formation of equine peripheral blood lymphocytes.
American journal of veterinary research    November 1, 1977   Volume 38, Issue 11 1775-1779 
Tarr MJ, Olsen RG, Krakowka GS, Cockerell GL, Gabel AA.Erythrocyte rosette (ER) formation of equine peripheral blood lymphocytes (PBL) was characterized. Guinea pig and, to a lesser extent, human erythrocytes formed ER; cat, cow, dog, hamster, mouse, rat, and sheep erythrocytes showed negligible rosetting properties. Conditions of the assay were varied to determine which procedure allowed the largest percentage of rosette formation. The PBL from 20 normal horses were then assayed, averaging 38 +/- 2% ER. To characterize the erythrocyte receptor as being on T or B cells, equine thymocytes from 6 foals were assayed; the thymocytes formed an average ...
Paroxysmal atrial fibrillation in a racehorse.
Australian veterinary journal    November 1, 1977   Volume 53, Issue 11 545-549 doi: 10.1111/j.1751-0813.1977.tb07943.x
Rose RJ, Davis PE.A 4-year-old thoroughbred stallion with a history of loss of racing form was studied over a period of approximately 7 months. At the initial examination he showed positive T waves in 1 chest lead and wandering of the pacemaker. This was followed by an episode of paroxysmal atrial fibrillation which disappeared spontaneously and was replaced by significant T wave changes in all the chest leads. During a period when these changes persisted, there was progressive lengthening of the P wave and the P-R interval. Because the last ECG showed evidence of intra-atrial block, first degree A-V block and ...
Studies on the equine placenta. III. Ultrastructure of the uterine glands and the overlying trophoblast.
Journal of reproduction and fertility    November 1, 1977   Volume 51, Issue 2 433-437 doi: 10.1530/jrf.0.0510433
Samuel CA, Allen WR, Steven DH.Ultrastructural studies of the uterine glands at intervals during pregnancy in the mare show that secretory activity continues after formation of the placental exchange units. The nature of the glandular secretion appeared initially to be proteinaceous, but cellular debris was also present during the last third of gestation. These secretions were absorbed by the trophoblast overlying the mouths of the glands. The fate secretions and their significance for the fetus and placenta are unknown.
Studies related to the metabolism of anabolic steroids in the horse: 19-nortestosterone.
Xenobiotica; the fate of foreign compounds in biological systems    November 1, 1977   Volume 7, Issue 11 683-693 doi: 10.3109/00498257709038698
Houghton E.1. The metabolism of 19-nortestosterone in a cross-bred horse has been studied using 14C-labelled material. 2. Two neutral metabolites isolated from urinary extracts by column chromatography were identified as isomers of 3-hydroxyestran-17-one and estrane-3,17-diol by g.l.c.-mass spectrometry. 3. The stereochemistry of the two metabolites has been investigated by comparison of the retention times of their trimethylsilyl derivatives with those of standard steroids of known configuration.
Staining of glycosaminoglycans in intervertebral disc cells.
Research in veterinary science    November 1, 1977   Volume 23, Issue 3 351-355 
Butler WF, Pousty I.Disc material from horse, ox, sheep, pig, dog and cat was stained by the Alcian-blue-critical electrolyte concentration technique and with the standard and two-step periodic acid Schiff methods. The effects of pretreatment with hyaluronidase and with chondroitinase was also evaluated. There appears to be a small increase in total cellular glycosaminoglycan content with age in all species: cellular material of high molecular weight however only increases in aged animals. The degree of sulphation of cellular glycosaminoglycans does not vary with age or with position in the disc.
Thiamine measurements in horses with laryngeal hemiplegia.
The Veterinary record    October 29, 1977   Volume 101, Issue 18 373-374 doi: 10.1136/vr.101.18.373
Duncan ID, Griffiths IR, Baker GJ.No abstract available
An epidemic of venereal infection in thoroughbreds.
The Veterinary record    October 29, 1977   Volume 101, Issue 18 359-360 doi: 10.1136/vr.101.18.359
O'Driscoll JG, Troy PT, Geoghegan FJ.The clinical pattern, bacteriological investigation and subsequent treatment of a serious outbreak of venereal disease in stud farms on both sides of the Irish Sea is described. The consistency with which Bacillus proteus was isolated from infected mares and stallions was remarkable. Prompt treatment with ampicillin, to which the organism was sensitive in vitro, eradicated the disease. No local treatment was applied.
Circular dichroism of porcine, bovine, and equine pancreatic phospholipases A2 and their zymogens. Unusual conformations simulating helix content.
Biochimica et biophysica acta    October 26, 1977   Volume 494, Issue 2 285-292 doi: 10.1016/0005-2795(77)90157-x
Jirgensons B, de Haas GH.Conformation of porcine, bovine, and equine pancreatic phospholipases A2 (EC 3.1.1.4) and their zymogens was studied by the circular dichroism (CD) probe in the far and near ultraviolet spectral zones. All these phospholipases and their zymogens displayed CD curves suggesting the presence of moderate amounts of α-helical conformation. However, on the basis of known primary structure and recent X-ray structural analysis of prophospholipase A2 crystals (Drenth, J., Enzing, C.M., Kalk, K.H. and Vessies, J.C.A. (1976) Nature 264, 373–377), it has to be concluded that the positive CD band cen...
Arrhenoblastoma in a mare.
Journal of the American Veterinary Medical Association    October 15, 1977   Volume 171, Issue 8 754-757 
Mills JH, Fretz PB, Clark EG, Ganjam VK.An ovarian neoplasm measuring 10 by 8 by 6 cm was surgically removed from a 14-year-old Appaloosa mare. For 2 years prior to surgery, the mare had manifested marked behavioral changes, becoming aggressive toward other broodmares. Histologically, the tumor was found to be an arrhenoblastoma. Preoperative endocrinologic findings (high serum testosterone and low serum estradiol concentrations) supported the diagnosis.
Studies on a number of erythrocytic enzymes and intermediate products of equine erythrocyte metabolism.
Tijdschrift voor diergeneeskunde    October 15, 1977   Volume 102, Issue 20 1197-1203 
Franken P, Schotman JH.The activities and concentrations of a number of erythrocytic enzymes and intermediate products of erythrocyte metabolism were determined in twenty-one normal standard-bred horses which were studied clinically and biochemically. These studies showed that equine anaerobic glycolysis is characterized by a biochemical pattern similar to that observed in human PK deficiency. The greater sensitivity of equine haemoglobin to oxidants is attributable either to low stability of GSH, which may be due either to the low activity of GR or that of 6PGD as observed in the studies. In addition, the saturatio...
[The arterial vessels and their intraosseous course in the leg bones of foals. II. Humerus].
DTW. Deutsche tierarztliche Wochenschrift    October 5, 1977   Volume 84, Issue 10 378-382 
Pohlmeyer K, Hertsch B.The arterial blood vessels in 24 humeri of equine fetusses and foals are described. The relation between the age and the distribution of these arteries are explained and completely discussed.
The actions of the beta-adrenoceptor blocking agents propranolol and metoprolol in the maximally exercised horse [proceedings].
The Journal of physiology    October 1, 1977   Volume 271, Issue 2 39P-40P 
Snow DH, Summers RJ.No abstract available
Prognosis of equine cardiac conditions.
Equine veterinary journal    October 1, 1977   Volume 9, Issue 4 181-182 doi: 10.1111/j.2042-3306.1977.tb04022.x
Holmes JR.No abstract available
Immunological properties of two related fragments from human and equine growth hormones.
European journal of immunology    October 1, 1977   Volume 7, Issue 10 701-704 doi: 10.1002/eji.1830071010
Zakin MM, Peña C, Poskus E, Stewart JM, Paladini AC.The immunological properties of a synthetic human growth hormone fragment comprising the amino acids 73 through 128 and of the homologous natural horse growth fragment formed by amino acids 73 through 123, have been comparatively studied. Antisera obtained in rabbits inoculated with the native human hormone or with the fragments, were used. By hemagglutination experiments both fragments have the same reactivity toward the anti-human growth hormone serum, but complement fixation curves detect the existence of at least two populations of antibodies presumably originated against the sequence 73-1...
Some reproductive statistics from the Polish National Stud.
Equine veterinary journal    October 1, 1977   Volume 9, Issue 4 238-239 doi: 10.1111/j.2042-3306.1977.tb04040.x
Symanski TA.No abstract available
The identification of Babesia equi in Australia.
Australian veterinary journal    October 1, 1977   Volume 53, Issue 10 461-464 doi: 10.1111/j.1751-0813.1977.tb05459.x
Mahoney DF, Wright IG, Frerichs WM, Groenendyk S, O'Sullivan BM, Roberts MC, Waddell AH.A Babesia parasite, isolated from the blood of a horse at Bowral, New South Wales, was identified on the basis of its morphological features, host specificity and serological reactions, as Babesia equi (Laveran 1901). The case was originally reported by Churchill and Best (1976, Aust. vet. J. 52: 487) and is the first record of equine babesiosis in Australia. In preliminary studies, the organism produced only a mild disease in an intact horse, but caused the typical clinical syndrome of acute babesiosis in a splenectomised horse, which died 19 days after the intravenous inoculation of the para...
A correlation of the endoscopic and pathological changes in subclinical pathology of the horse’s larynx.
Equine veterinary journal    October 1, 1977   Volume 9, Issue 4 220-225 doi: 10.1111/j.2042-3306.1977.tb04036.x
Duncan ID, Baker GJ, Heffron CJ, Griffiths IR.The larynges of 6 horses were examined endoscopically and the findings correlated with the gross and histological appearance of the intrinsic laryngeal muscles and their nerve supply. In all cases it appeared that the balance between abductor and adductor muscle groups had been lost due to preferential atrophy of individual muscles or groups of muscles. The laryngeal abnormalities recorded were asymmetry of the larynx with asynchronous left sided abduction and fluttering or trembling of the left vocal cord and arytenoid cartilage. It is suggested that these changes represent the early signs of...
[Dilution of stallion sperm].
Veterinariia    October 1, 1977   Issue 10 86-88 
Naumenkov AI, Roman'kova NK.No abstract available
Telemetric measurements of strain in the metacarpus of the horse: a pilot study.
American journal of veterinary research    October 1, 1977   Volume 38, Issue 10 1675-1677 
Sumner-Smith G, Bell M, Manley P, Caddell E, Hoare J.The advances made by the use of a telemetric system in the study of bone strain in a free-moving horse are reported. A rosette strain gauge was bonded to the craniomedial aspect of the metacarpus of the horse. Attachment of a miniature FM transmitter to lead wires facilitated telemetric transmission of of resistance changes which corresponded to limb movement. During 3 different gaits, the trace pattern remained similar, although frequency and amplitude varied. The tracings were similar to those reported in other species in which nontelemetric transmission was used.
An experimental study of autologous digital tendon transplants in the horse.
Equine veterinary journal    October 1, 1977   Volume 9, Issue 4 231-237 doi: 10.1111/j.2042-3306.1977.tb04039.x
Strömberg B, Tufvesson G.Four autologous tendon grafting techniques, bipedicle, pedicle and free grafts of the deep digital flexor tendon and free grafts from the lateral digital extensor tendon were described. The vascularization and remodelling of the transplant and the reactions in the donor, as well as the recipient tendon, were studied by means of microangiographic and histochemical methods. The results indicated that regardless of the technique used the grafts were revascularized and replaced by a highly orientated and organized tendon. The use of free grafts may therefore be worthwhile in treatment of severe te...
Cytochemical staining of equine blood and bone marrow cells.
Equine veterinary journal    October 1, 1977   Volume 9, Issue 4 205-207 doi: 10.1111/j.2042-3306.1977.tb04032.x
Tschudi P, Archer RK, Gerber H.No abstract available
A case of primary lymphoid leukaemia in a horse.
Equine veterinary journal    October 1, 1977   Volume 9, Issue 4 216-219 doi: 10.1111/j.2042-3306.1977.tb04034.x
Roberts MC.Progressive leukaemic changes and a persistent anaemia were demonstrated in the blood of a 7 year old gelding, which had shown early signs of lowered performance and unthriftiness, and later developed dependent oedema and became dull and listless. The total leucocyte count, initially within the normal range although reflecting an absolute lymphocytosis, increased fourfold in 6 days from excessive lymphoid production involving predominantly the more immature cell types; lymphoblasts, prolymphocytes and large lymphocytes. The severity of the condition was confirmed by bone marrow biopsy.
Analysis of normal equine serum using the SMA 12/60 Autoanalyzer.
Veterinary medicine, small animal clinician : VM, SAC    October 1, 1977   Volume 72, Issue 10 1629-1633 
Porter T, McCashin FB.No abstract available
The clinician’s approach to equine cardiology.
Equine veterinary journal    October 1, 1977   Volume 9, Issue 4 176-177 doi: 10.1111/j.2042-3306.1977.tb04020.x
Glendinning SA.The author considers some of the difficulties the clinician may be faced with when giving an opinion on a horse with a cardiac abnormality. The 3 types of cardiological cases presented to the practitioner are described. The first 2 categories both exhibit a reduction in performance either with loss of bodily conduction or without it. The third group, which is the most troublesome for the clinician, involves the horse which shows a cardiological abnormality but is otherwise apparently normal.
Cardiological problems in equine medicine.
Equine veterinary journal    October 1, 1977   Volume 9, Issue 4 173-175 doi: 10.1111/j.2042-3306.1977.tb04018.x
Littlewort MC.This paper outlines the major problems in evaluating and assessing prognosis in horses with minor cardiac abnormalities. It emphasises that progress will only be made if adequate data on the "natural history" of equine cardiac disease can be collected. This will necessitate a long-term study of suitable cases and will require the collaboration of specialist institutions and general practitioners if it is to be successful.
Pacing techniques in assessing cardiac function in the horse.
Equine veterinary journal    October 1, 1977   Volume 9, Issue 4 178-180 doi: 10.1111/j.2042-3306.1977.tb04021.x
O'Callaghan MW.The problem of transitory cardiac arrhythmias in equidae is discussed particularly with regard to the referral of suspect cases to specialist institutions for second opinion. Recently developed electro-stimulation techniques designed to uncover problem arrythmias, are briefly described and their potential in the analysis of cardiac electrical function under varying conditions is reviewed. The author cautions on the too rapid evaluation of the techniques for this purpose while remaining optimistic of the potential of electro-stimulation in the objective analysis of cardiac electric parameters.