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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Idiopathic acute hepatic disease in horses: 12 cases (1982-1992).
Journal of the American Veterinary Medical Association    June 15, 1994   Volume 204, Issue 12 1934-1937 
Messer NT, Johnson PJ.Acute hepatic disease was diagnosed in 16 horses during the study period. Twelve of those cases were characterized as idiopathic acute hepatic disease (IAHD). In 9 of the 12 (75%) cases of IAHD, the horses were female, and 7 of the 9 females were lactating and had been treated with tetanus antitoxin at parturition. Diagnosis of IAHD was based on anamnesis, clinical signs, and results of serum biochemical analyses, hepatic biopsy, and postmortem examination. Within 1 year of the illness, 75% (9/12) of the horses had died or had been euthanatized. Not all horses had the typical fulminant signs a...
Insurance for angular limb deformities in foals.
The Veterinary record    June 11, 1994   Volume 134, Issue 24 636 doi: 10.1136/vr.134.24.636-b
Ogden AL.No abstract available
Intestinal lymphangiectasia as a cause of chronic diarrhoea in a horse.
The Veterinary record    June 4, 1994   Volume 134, Issue 23 603-604 doi: 10.1136/vr.134.23.603
Milne EM, Woodman MP, Rowland AC, Patrick CJ, Arthur SJ.No abstract available
Necrotoxigenic E coli in rabbits and horses.
The Veterinary record    June 4, 1994   Volume 134, Issue 23 608 doi: 10.1136/vr.134.23.608-a
Ansuini A, Candotti P, Vecchi G, Falbo V, Minelli F, Caprioli A.No abstract available
Blood protein polymorphisms in the donkey (Equus asinus).
Animal genetics    June 1, 1994   Volume 25 Suppl 1 109-113 doi: 10.1111/j.1365-2052.1994.tb00413.x
Bell K.Transferrin, albumin, 6-phosphogluconate dehydrogenase and vitamin D-binding protein polymorphisms were detected in 242 feral and domesticated Australian donkeys by polyacrylamide gel electrophoresis, starch gel electrophoresis, autoradiography, immunoblotting with specific antisera and activity staining. All four TF and two ALB variants were donkey specific while only one of the PGD variants was donkey specific. The two GC variants were electrophoretically identical to the Equus caballus F and S proteins. Available evidence suggested that the TF, ALB, PGD and GC systems are controlled by co-d...
Effect of hypoxia on metabolic rate in awake ponies.
Journal of applied physiology (Bethesda, Md. : 1985)    June 1, 1994   Volume 76, Issue 6 2380-2385 doi: 10.1152/jappl.1994.76.6.2380
Korducki MJ, Forster HV, Lowry TF, Forster MM.To determine the effect of hypoxia on metabolic rate (VO2) of ponies, on 2 days we studied ponies that were breathing room air for 1 h followed by 5 h of either hypoxic hypoxia (fractional concn of inspired O2 = 0.126) or 5 h of CO hypoxia. Control arterial PO2 was 103 +/- 1.2 Torr, and at 5 min and 5 h of hypoxic hypoxia, arterial PO2 was 53.1 +/- 1.8 and 41.0 +/- 1.8 Torr, respectively. There was a time-dependent hypocapnia and alkalosis during hypoxic hypoxia. During CO hypoxia, carboxyhemoglobin increased to 25% after 30 min and remained constant thereafter. With increased carboxyhemoglobi...
Studies on the frequency and associations of equine leucocyte antigens in sarcoid and summer dermatitis.
Animal genetics    June 1, 1994   Volume 25 Suppl 1 75-80 doi: 10.1111/j.1365-2052.1994.tb00406.x
Lazary S, Marti E, Szalai G, Gaillard C, Gerber H.The equine leucocyte antigen (ELA) types and the clinical diagnosis for equine sarcoid and summer dermatitis were evaluated in 2026 horses representing five breeds. Data were analysed in unrelated animals and in family material. In the case of equine sarcoid, a strong association was observed between the ELA class II DW13 antigen and its effect on Swiss (cP < 0.001), French (cP < 0.0001) and Irish (cP < 0.01) Warmblood horses. The class I antigen A3 occurred more frequently in sarcoid-affected French horses (cP < 0.001). These results confirm our earlier findings (Gerber et al. 1988). Among Fr...
Respiratory mechanics of horses measured by conventional and forced oscillation techniques.
Journal of applied physiology (Bethesda, Md. : 1985)    June 1, 1994   Volume 76, Issue 6 2467-2472 doi: 10.1152/jappl.1994.76.6.2467
Young SS, Tesarowski D.Respiratory mechanics were compared using conventional and forced oscillation techniques in six conscious horses and a mechanical model of the equine respiratory system. The parameters calculated from conventional airflow and esophageal pressure measurements were pulmonary resistance and dynamic compliance. The impedance of the respiratory system was measured at 1, 2, and 3 Hz with the forced oscillation technique, and respiratory system resistance, compliance, inertance, and resonant frequency were calculated. Pulmonary resistance was 1.0 +/- 0.3 cmH2O.l-1.s, and pulmonary dynamic compliance ...
Hemorheologic alterations induced by incremental treadmill exercise in thoroughbreds.
American journal of veterinary research    June 1, 1994   Volume 55, Issue 6 854-861 
Geor RJ, Weiss DJ, Smith CM.Hemorheologic alterations induced by incremental treadmill exercise were examined in 5 Thoroughbreds. Blood viscosity; PCV; RBC filterability, density gradient profile, and shape; serum and RBC electrolyte concentrations; and plasma total solids and lactate concentrations were measured before exercise, at treadmill speeds of 9 and 13 m/s, and 10 minutes after exercise. Exercise was associated with significant (P < 0.05) increases in PCV, blood viscosity, and plasma total solids concentration. After adjustment of PCV to 40% by adding or removing each horse's own plasma, blood viscosity ...
Comparative genetic analysis of Swiss and Spanish isolates of Echinococcus granulosus by southern hybridization and Random Amplified Polymorphic DNA technique.
Applied parasitology    June 1, 1994   Volume 35, Issue 2 107-117 
Siles-Lucas M, Felleisen R, Cuesta-Bandera C, Gottstein B, Eckert J.Swiss and Spanish isolates of Echinococcus granulosus were compared using different molecular biological techniques: Genomic DNAs isolated from parasites originating from various intermediate hosts were subjected to Southern hybridization with different probes, the same source of DNA was used for DNA amplification using the Random Amplified Polymorphic DNA (RAPD) technique. With both methods the various isolates (metacestodes) of E. granulosus exhibited characteristic banding patterns which allowed us to assign them to the following groups of homologous profiles: (a) isolates of horse and donk...
Repair of a fracture of the fourth carpal bone in a yearling standardbred horse.
The Canadian veterinary journal = La revue veterinaire canadienne    June 1, 1994   Volume 35, Issue 6 371-372 
Field JR, Zaruby JF.No abstract available
Serological and genomic characterization of equine rotavirus VP4 proteins identifies three different P serotypes.
Virology    June 1, 1994   Volume 201, Issue 2 364-372 doi: 10.1006/viro.1994.1302
Isa P, Snodgrass DR.A series of viral reassortants was prepared between equine rotaviruses H1 (G5), H2 (G3), and L338 (G13) and human rotavirus ST3 (G4). All contained the VP4 cognate gene segment 4 from the equine parental virus and the VP7 cognate gene segment 9 from ST3. Using these viruses and antisera prepared to them, it was shown that each of the three equine viruses possessed a serologically distinct VP4 or P serotype with a > or = 16-fold difference in reciprocal cross-neutralization titers. H1 VP4 was closely related to that of porcine virus OSU, i.e., P7. L338 gene 4 was sequenced, and the sequence and...
Equine viral arteritis in donkeys in South Africa.
Journal of the South African Veterinary Association    June 1, 1994   Volume 65, Issue 2 40 
Paweska JT.No abstract available
Surface oximetry for intraoperative assessment of colonic viability in horses.
Journal of the American Veterinary Medical Association    June 1, 1994   Volume 204, Issue 11 1786-1789 
Snyder JR, Pascoe JR, Meagher DM, Thurmond MC.Surface oximetry was used to evaluate viability of the ascending colon in 60 horses with naturally occurring colonic volvulus or displacement. Tissue surface oxygen tension (PsO2) was measured on the serosal surface of the pelvic flexure after anatomic correction of the colonic obstruction. Horses with PsO2 > 20 mm of Hg were predicted to have viable colon; whereas, horses with PsO2 < or = 20 mm of Hg were predicted to have nonviable colon. Results of surface oximetry were compared with final outcome. For surface oximetry, sensitivity (ability to accurately identify colon that was nonvia...
Monoclonal antibody based competitive ELISA for the detection of specific antibodies against Coxiella burnetii in sera from different animal species.
Zentralblatt fur Bakteriologie : international journal of medical microbiology    June 1, 1994   Volume 281, Issue 1 61-66 doi: 10.1016/s0934-8840(11)80638-9
Jaspers U, Thiele D, Krauss H.A competitive ELISA system for the detection of antibodies against Coxiella (C.) burnetii in cattle, sheep, goats, horses and humans is described. The ELISA is based on a biotinylated monoclonal antibody with specificity for C. burnetii lipopolysaccharide in combination with streptavidin peroxidase. For evaluation and statistical analysis, 413 sera from cattle, sheep, goats, horses and humans were tested in parallel in the indirect immunofluorescence test (IFT). Furthermore, a total of 448 bovine and human sera were also tested with an indirect ELISA and 47 sheep sera were investigated using t...
Serological relationship between a donkey alphaherpesvirus (isolate M7/91) and equid herpesvirus type 1 and 4.
Journal of the South African Veterinary Association    June 1, 1994   Volume 65, Issue 2 64-66 
Paweska JT, Gerdes T, Van Heerden J.Rabbit hyperimmune serum prepared against a donkey alphaherpesvirus isolate (M7/91), and against EHV-1 and EHV-4 was used to characterise the antigenic relationship between these 3 viruses. Serum from immunised rabbits was always more specific for homologous virus and showed different cross reactivity for heterologous virus. It was concluded that the immunologic relationship between the M7/91 isolate and EHV-1, was closer than that between this isolate and EHV-4. A serological survey of donkeys (n = 116) and horses (n = 57) revealed evidence of the presence of neutralising antibody to M7/91 in...
Measurements of heart scores and heart weights in horses of two different morphic body types.
Comparative biochemistry and physiology. Comparative physiology    June 1, 1994   Volume 108, Issue 2-3 175-178 doi: 10.1016/0300-9629(94)90083-3
Hanson CM, Kline KH, Foreman JH.Heart scores (the arithmetic mean of the QRS durations of the three bipolar limb leads for 10 cycles) and heart weights were determined from five draft type horses and five racing type horses, and evaluated for relationships between heart score and heart size within and between the two different types of horses. Horses were killed using a captive bolt gun, and actual heart weights were recorded using an electronic digital scale. The linear regression equation for heart weight versus heart score had a significant (P < 0.05) negative slope for racing types. The regression coefficients for heart ...
Albumin quotient, IgG concentration, and IgG index determinations in cerebrospinal fluid of neonatal foals.
American journal of veterinary research    June 1, 1994   Volume 55, Issue 6 741-745 
Andrews FM, Geiser DR, Sommardahl CS, Green EM, Provenza M.Total protein (TP), albumin, and IgG concentrations were measured in CSF from the atlanto-occipital (AO) and lumbosacral (LS) sites and in serum of 15 clinically normal neonatal foals < or = 10 days old (mean, 7.0 days). The albumin quotient (AQ; CSF albumin/serum albumin x 100) and IgG index ([CSF IgG/serum IgG] x [serum albumin/CSF albumin]), indicators of blood-brain barrier permeability and intrathecal IgG production, respectively, were then calculated. Mean +/- SD values obtained from the foals of this study were: serum albumin, 2,900 +/- 240 mg/dl; serum IgG, 1,325 +/- 686 mg/dl; AO CSF ...
[The clinical case. Rupture of the musculus fibularis tertius].
Tierarztliche Praxis    June 1, 1994   Volume 22, Issue 3 208-295 
Granacher A.No abstract available
Inheritance of an anomalous Pi marker in horses.
Animal genetics    June 1, 1994   Volume 25 Suppl 1 103-104 doi: 10.1111/j.1365-2052.1994.tb00412.x
Suzuki Y, Stormont CJ.No abstract available
Mechanism of reduction in alveolar-arterial PO2 difference by helium breathing in the exercising horse.
Journal of applied physiology (Bethesda, Md. : 1985)    June 1, 1994   Volume 76, Issue 6 2794-2801 doi: 10.1152/jappl.1994.76.6.2794
Erickson BK, Seaman J, Kubo K, Hiraga A, Kai M, Yamaya Y, Wagner PD.Previous work has shown that replacing N2 in air with He at the same inspired O2 fraction reduces the exercise-induced alveolar-arterial PO2 difference (AaPO2) in horses but has provided no mechanism explaining this effect. We sought to distinguish among possible causes by using the multiple inert gas elimination technique. Six horses were studied on a high-speed treadmill while they breathed either ambient air or normoxic He-O2. O2 uptake reached 138.0 ml.min-1.kg-1 and was not affected by He-O2. Temperature-corrected arterial PO2 was 76.7 Torr (air) and 86.9 Torr (He-O2) (P < 0.01). Corre...
Effect of sodium cromoglycate on light racehorses with elevated metachromatic cell numbers on bronchoalveolar lavage and reduced exercise tolerance.
Journal of veterinary pharmacology and therapeutics    June 1, 1994   Volume 17, Issue 3 237-244 doi: 10.1111/j.1365-2885.1994.tb00239.x
Hare JE, Viel L, O'Byrne PM, Conlon PD.Some young horses with clinical signs of small airway disease demonstrate increased metachromatic cell numbers on bronchoalveolar lavage. The purpose of this study was to determine the effect of sodium cromoglycate treatment on clinical signs, bronchoalveolar lavage cytology and bronchoalveolar lavage histamine parameters in these horses. Twelve racehorses (age: 3.4 +/- 1.6 years) with a history of respiratory embarrassment at exercise, clinical signs of obstructive airway disease and bronchoalveolar lavage metachromatic cell differential greater than 2% were selected. Horses were randomly ass...
Structural organization and neuropeptide distributions in the equine enteric nervous system: an immunohistochemical study using whole-mount preparations from the small intestine.
Cell and tissue research    June 1, 1994   Volume 276, Issue 3 523-534 doi: 10.1007/BF00343949
Pearson GT.The architecture and neurochemistry of the enteric nervous system was studied by use of whole-mount preparations obtained by microdissection of the horse jejunum. A myenteric plexus and two plexuses within the submucosa were identified. The external submucosal plexus lying in the outermost region of the submucosa had both neural and vascular connections with the inner submucosal plexus situated closer to the mucosa. Counts of neurones stained for NADH-diaphorase demonstrated the wide variation in size, shape and neurone content of individual ganglia in both the external and internal submucosal...
[The “lethal white foal” syndrome].
Tierarztliche Praxis    June 1, 1994   Volume 22, Issue 3 252-255 
Blendinger C, Müller G, Bostedt H.The lethal white foal syndrome (congenital intestinal aganglionosis) was diagnosed by history, clinical signs and pathological findings in a female foal, born in March 1992, that was an offspring of two overo-spotted paint horses. The syndrome is a congenital innervation defect of the gastrointestinal tract. A literature review of this condition, relatively unknown in Germany, is given.
Structural and functional characterization of elastases from horse neutrophils.
The Biochemical journal    June 1, 1994   Volume 300 ( Pt 2), Issue Pt 2 401-406 doi: 10.1042/bj3000401
Dubin A, Potempa J, Travis J.In order better to understand the pathophysiology of the equine form of emphysema, two elastinolytic enzymes from horse neutrophils, referred to as proteinases 2A and 2B, have been extensively characterized and compared with the human neutrophil proteinases, proteinase-3 and elastase. Specificity studies using both the oxidized insulin B-chain and synthetic peptides revealed that cleavage of peptide bonds with P1 alanine or valine residues was preferred. Further characterization of the two horse elastases by N-terminal sequence and reactive-site analyses indicated that proteinases 2A and 2B ha...
Abortion due to equine herpesvirus in southern Brazil. Weiblen R, Rabuske M, Rebelatto MC, Nobre VM, Canabarro TF.We report an outbreak of abortion due to equine herpesvirus (EHV) in 5 mares between 9 and 11 months of gestation, from a herd of 22 Thoroughbred mares. Equine herpesvirus was isolated from extracts of the liver, spleen and thymus but not from the lungs of a 9-month fetus grown in Rabbit Kidney (RK13) cells. The virus was identified by electron microscopy, where virus particles could be seen in the nucleus of infected cells, and by the fluorescent antibody technique with polyclonal antibodies against the whole virus. Anamnesis, necropsy, histopathology, bacteriology, and virology data suggest ...
[Prognostic parameters in equine colic].
Tierarztliche Praxis    June 1, 1994   Volume 22, Issue 3 256-263 
Ebert R.A retrospective study was performed on 271 horses with colic referred to the I. Medizinische Tierklinik within a period of 2 years, to examine the prognostic value of different clinical and diagnostic laboratory parameters by Student's t-test and the Chi-quadratic test. The following quantitative parameters presented a highly significant prognostic value (P < 0.0001): capillary refill time, pulse rate, heart rate, respiratory rate, hematocrit, hemoglobin concentration, blood lactate, base excess and anion gap. The intensity of colic signs, the degree of disturbance of the patient's gen...
Characterization of muscarinic receptor subtype mediating contraction and relaxation in equine coronary artery in vitro.
Journal of veterinary pharmacology and therapeutics    June 1, 1994   Volume 17, Issue 3 226-231 doi: 10.1111/j.1365-2885.1994.tb00237.x
Obi T, Kabeyama A, Nishio A.In coronary arterial rings isolated from horses, 10(-8)-10(-6) mol/l acetylcholine (ACh) induced concentration-dependent contractions which were potentiated by the removal of endothelium and by pretreatment with L-nitro-arginine (LNAG) or methylene blue (MB). Relatively lower concentrations of ACh (10(-14)-10(-8) mol/l) induced relaxation when the coronary rings were contracted by phenylephrine (PE). ACh-induced contractions in the coronary rings without endothelium were competitively inhibited by each muscarinic subtype selective antagonist in the following order of potency: 4-diphenylacetoxy...
Activity of coagulation and fibrinolysis parameters in animals.
Arzneimittel-Forschung    June 1, 1994   Volume 44, Issue 6 793-797 
Karges HE, Funk KA, Ronneberger H.Using diagnostics for the determination of clotting factors and fibrinolytic parameters in human plasma, samples from rat, guinea pig, rabbit, cat, dog, sheep, cattle, horse, pig, and monkey were analysed. The human system was employed even for standard curves and controls. Results obtained in this way are relative values in relation to pooled fresh human plasma of healthy donors which is defined to contain 100% of the norm or 1 unit of each factor per 1 ml. Under these conditions, marked differences between the human clotting system and those of different animal species appear. Thus, rabbits ...
A rapid method for the analysis of influenza virus genes: application to the reassortment of equine influenza virus genes.
Virus research    June 1, 1994   Volume 32, Issue 3 391-399 doi: 10.1016/0168-1702(94)90087-6
Adeyefa CA, Quayle K, McCauley JW.We describe a rapid method for genetic characterisation of influenza virus genes using reverse transcription and amplification by polymerase chain reaction (RT/PCR) of all virus segments simultaneously (multiplex RT/PCR) using primers based on the conserved terminal sequences. The product has been shown to be suitable for determination of partial nucleotide sequences which can be used to search nucleotide sequence databases and rapidly map the genetic origin of each segment. We illustrate the use of the method by analysing genetic reassortment in H7N7 equine influenza viruses.