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Topic:Clinical Findings

Clinical findings in horses encompass a range of observable signs and symptoms identified during veterinary examinations that contribute to diagnosing and managing equine health conditions. These findings can include physical observations, such as changes in behavior, posture, or gait, as well as physiological measurements like heart rate, respiratory rate, and temperature. Diagnostics may also involve laboratory tests, imaging, and other diagnostic procedures to assess organ function and detect abnormalities. Recognizing and interpreting clinical findings are essential components of veterinary practice, aiding in the identification of diseases, monitoring treatment progress, and guiding therapeutic interventions. This page brings together peer-reviewed research studies and scholarly articles that explore the methodologies, interpretations, and implications of clinical findings in the context of equine health care.
Outcomes of horses treated with removal of a laryngoplasty prosthesis.
Veterinary surgery : VS    January 4, 2019   Volume 48, Issue 4 465-472 doi: 10.1111/vsu.13150
Fitzharris LE, Lane JG, Allen KJ.To determine the proportion of horses treated by laryngoplasty prosthesis removal (LPR) for complications associated with prosthetic laryngoplasty (LP), the reason for LPR, and the outcome of horses undergoing LPR to manage iatrogenic coughing/dysphagia. Methods: Retrospective study. Methods: Client-owned horses treated with LP (n = 1202) and LPR (n = 58). Methods: Clinical case records were reviewed to determine the number of horses treated with LP and LPR by the same surgeon. Historical, clinical, endoscopic, and surgical data were extracted for those horses undergoing LPR. Long-term...
Outcome following computed tomographic imaging and subsequent surgical removal of keratomas in equids: 32 cases (2005-2016).
Journal of the American Veterinary Medical Association    January 4, 2019   Volume 254, Issue 2 266-274 doi: 10.2460/javma.254.2.266
Katzman SA, Spriet M, Galuppo LD.OBJECTIVE To describe the use of CT in the diagnosis of and presurgical planning for equids with keratomas treated by hoof wall resection and determine postoperative complications and outcome. DESIGN Retrospective case series. ANIMALS 29 horses and 3 mules with keratomas treated by partial or complete hoof wall resection following CT imaging of the distal portion of the affected extremity from 2005 through 2016. PROCEDURES For each equid, physical examination and lameness evaluation were performed, followed by imaging of the distal portion of the affected extremity. A tentative diagnosis of ke...
Evaluation of a portable device for assessment of motility in stallion semen.
Reproduction in domestic animals = Zuchthygiene    December 28, 2018   Volume 54, Issue 3 514-519 doi: 10.1111/rda.13390
Buss T, Aurich J, Aurich C.In horse breeding, quality assessment of semen before insemination is often requested. Non-laboratory-based techniques for objective analysis of sperm motility are thus of interest. The aim of this study was evaluating a portable device for semen analysis (Ongo sperm test) and its comparison with computer-assisted semen analysis (CASA). Semen was collected from 10 stallions, diluted to 100, 50 and 25 × 106  sperm/ml and analysed for total (TM) and progressive motility (PM). The final sperm concentration influenced total motility analysed by Ongo (p < 0.05) which was higher at 100 × 10...
Predictive value of plasma and peritoneal creatine kinase in horses with strangulating intestinal lesions.
Veterinary surgery : VS    December 26, 2018   Volume 48, Issue 2 152-158 doi: 10.1111/vsu.13147
Kilcoyne I, Nieto JE, Dechant JE.To determine the ability of plasma and peritoneal creatine kinase (CK) to predict the presence of a strangulating lesion in horses presented for colic. Methods: Prospective clinical study. Methods: Ten healthy control horses and 61 clinical colic cases. Methods: Creatine kinase activity was measured in peritoneal fluid and plasma of 10 healthy horses and 61 horses presenting for colic (40 horses with nonstrangulating lesions and 21 horses with strangulating lesions). Information on other blood and peritoneal fluid variables, signalment, results from the physical examination, outcome, requireme...
A comparison of two ketamine doses for field anaesthesia in horses undergoing castration.
Equine veterinary journal    December 26, 2018   Volume 51, Issue 4 458-463 doi: 10.1111/evj.13052
Harðardóttir H, Murison PJ, Blissitt K, Olason S, Clutton RE.Ketamine at 2.2 mg/kg given i.v. is often used to induce anaesthesia for surgical procedures in horses under field conditions. Commonly, additional doses are needed to complete the surgery. We hypothesised that surgical conditions would be improved when 5 mg/kg of ketamine was used to induce anaesthesia, while induction and recovery qualities would not differ from those when 2.2 mg/kg ketamine was used. Objective: To compare the anaesthetic effects of two ketamine doses (5 and 2.2 mg/kg) during field anaesthesia for castration of horses. Methods: Prospective, randomised, blinded, clinical stud...
Comparison of the reliability of snap foal Ig test, Gamma-Check E test, refractometry and electrophoresis for determining the immune status of newborn foals in the first hours of life.
Acta veterinaria Hungarica    December 26, 2018   Volume 66, Issue 4 573-586 doi: 10.1556/004.2018.051
Kummer LL, Govaere J, Egri B.Twenty-eight warmblood mares were monitored during their late pregnancy in the Teaching Hospital of Ghent University. The reliability of two commercial assays (enzyme immunoassay and glutaraldehyde coagulation test) used for determining the IgG concentrations of their newborn foals was tested. Mammary secretions were examined at the time of foaling (T0), and then 4 (T1) and 8 (T2) hours after foaling by refractometry and electrophoresis. The foals' blood IgG levels were measured at T1 and T2 as a routine clinical diagnostic examination using two different commercial test kits (SNAP Foal Ig and...
Cardiovascular variables in eventing and endurance horses over a season.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology    December 14, 2018   Volume 21 67-78 doi: 10.1016/j.jvc.2018.08.004
Lorello O, Ramseyer A, Burger D, Gerber V, Navas de Solis C.The objectives of this study were to describe the changes in clinical cardiovascular examination variables over a competition season in groups of competitive eventing and endurance horses and to compare these findings to non-competitive controls of the same breeds. Methods: This study included two eventing horses, 11 endurance horses, and 13 eventing and seven endurance control breed-matched horses. Methods: Cardiovascular examinations were performed before starting the competition season, in the middle and at the peak/end of the competition season. Examinations included auscultation of the he...
Neuromyotonia in a horse.
Journal of veterinary internal medicine    December 3, 2018   Volume 33, Issue 1 287-291 doi: 10.1111/jvim.15353
Zakia LS, Palumbo MIP, Teixeira RBC, Resende LAL, Soares MP, de Oliveira-Filho JP, Amorim RM, Borges AS.This article describes the clinical and electromyographic findings of neuromyotonia in a 19-month-old male crossbred Quarter Horse that presented with stiffness and muscle asymmetry in the hind limbs as well as sacrococcygeal, paravertebral, and gluteal myokymia. An electromyographic study showed spontaneous continuous muscle fiber activity with high-frequency discharges, fibrillations, positive sharp waves, fasciculation potentials, and complex repetitive discharges. Histological examination of the gluteal muscle showed a mixed neurogenic and myopathic pattern. The findings are consistent wit...
Factors associated with survival, laminitis and insulin dysregulation in horses diagnosed with equine pituitary pars intermedia dysfunction.
Equine veterinary journal    December 3, 2018   Volume 51, Issue 4 440-445 doi: 10.1111/evj.13041
Horn R, Bamford NJ, Afonso T, Sutherland M, Buckerfield J, Tan RHH, Secombe CJ, Stewart AJ, Bertin FR.Pituitary pars intermedia dysfunction (PPID) is a commonly described endocrine disorder in higher latitudes of the Northern hemisphere but the description of the disease at lower latitudes and in the Southern hemisphere is limited. Objective: Document the clinical features of PPID at different Australian latitudes and climates, and investigate factors associated with survival, laminitis and insulin dysregulation (ID). Methods: Retrospective study of 274 equids from eight institutions across Australia. Methods: A diagnosis of PPID was based on endogenous ACTH, overnight dexamethasone suppressio...
Clinical insights: Biomechanics and lameness diagnosis.
Equine veterinary journal    December 1, 2018   Volume 51, Issue 1 5-6 doi: 10.1111/evj.13036
Gómez Álvarez CB.No abstract available
Isolation and comparison of Arcanobacterium hippocoleae isolates from the genital tract of 15 mares.
Veterinary microbiology    November 28, 2018   Volume 228 129-133 doi: 10.1016/j.vetmic.2018.11.026
Pégné JC, Duquesne F, Laugier C, Lequeux G, Petry S.The present study reports the isolation of A. hippocoleae from genital swabs of 15 apparently healthy mares (at least one had an abortion one month earlier) and describes the genotypic and phenotypic characterisation of these strains. The mares were of eight different breeds with a thoroughbred dominance and came from 11 breeding farms located in the French region of Brittany. 16S rRNA gene sequencing confirmed the species' identification by comparing it with reference strain A. hippocoleae CIP 106850. Some degree of natural divergence within A. hippocoleae was observed by 16S rRNA sequencing ...
The Use of Bone Marrow Concentrate in the Treatment of Full-Thickness Chondral Defects.
HSS journal : the musculoskeletal journal of Hospital for Special Surgery    November 26, 2018   Volume 15, Issue 1 96-99 doi: 10.1007/s11420-018-9647-z
Apostolakos JM, Lazaro L, Williams RJ.This article is a critical analysis of a study, "Minimally Manipulated Bone Marrow Concentrate Compared with Microfracture Treatment of Full-Thickness Chondral Defects: A One-Year Study in an Equine Model," by Chu et al. (. 100(2):138-146, 2018). The investigation compared two interventions in the management of full-thickness chondral defects in an equine model: autologous bone marrow concentrate without concomitant microfracture treatment versus microfracture treatment alone. This review analyzes the methodology and results of their investigation and examines how their findings may influence ...
Bone marrow lesions of the distal condyles of the third metacarpal bone are common and not always related to lameness in sports and pleasure horses. De Guio C, Ségard-Weisse E, Thomas-Cancian A, Schramme M.The metacarpophalangeal joint is a common site of pain in horses. Little information is available about bone marrow lesions in the distal condyles of the third metacarpal bone in sports and pleasure horses. Aims of this prospective, retrospective, observational study were to evaluate the prevalence of bone marrow lesions in the distal condyles of the third metacarpal bone, to describe their anatomic distribution and to correlate lesions with the presence of lameness and the level and type of activity. All sports and pleasure horses undergoing standing low-field MRI of the front fetlock region ...
Active vaccination against interleukin-5 as long-term treatment for insect-bite hypersensitivity in horses.
Allergy    November 25, 2018   Volume 74, Issue 3 572-582 doi: 10.1111/all.13659
Fettelschoss-Gabriel A, Fettelschoss V, Olomski F, Birkmann K, Thoms F, Bühler M, Kummer M, Zeltins A, Kündig TM, Bachmann MF.Insect-bite hypersensitivity (IBH) in horses is a chronic allergic dermatitis caused by insect bites. Horses suffer from pruritic skin lesions, caused by type-I/type-IV allergic reactions accompanied by prominent eosinophil infiltration into the skin. Interleukin-5 (IL-5) is the key cytokine for eosinophils and we have previously shown that targeting IL-5 by vaccination reduces disease symptoms in horses. Here, we analyzed the potential for long-term therapy by assessing a second follow-up year of the previously published study. The vaccine consisted of equine IL-5 (eIL-5) covalently linked to...
The pharmacokinetics and pharmacodynamics of intravenous hydromorphone in horses.
Veterinary anaesthesia and analgesia    November 22, 2018   Volume 46, Issue 3 395-404 doi: 10.1016/j.vaa.2018.11.001
Reed R, Barletta M, Mitchell K, Hanafi A, Bullington A, Knych H, Quandt J, Ryan C, Giguère S.Describe the pharmacokinetics and pharmacodynamics of intravenous hydromorphone in healthy horses. Methods: Masked, randomized, cross-over, Latin square design. Methods: A group of eight healthy adult horses METHODS: Horses were administered each of four treatments with an 8 day washout. Treatments groups included intravenous hydromorphone 0.02 mg kg (LD), 0.04 mg kg (MD), 0.08 mg kg (HD) and saline (P). Blood samples for hydromorphone analysis were obtained for 24 hours after treatment. Plasma hydromorphone was quantified and pharmacokinetic parameters were determined using non-compartmental ...
Advances in Echocardiography.
Progress in cardiovascular diseases    November 22, 2018   Volume 61, Issue 5-6 389 doi: 10.1016/j.pcad.2018.11.010
Lavie CJ.No abstract available
The prevalence of temporal bone fractures is high in horses with severe temporohyoid osteoarthropathy. Tanner J, Spriet M, Espinosa-Mur P, Estell KE, Aleman M.Temporohyoid osteoarthropathy is a well-recognized cause of equine neurologic disease. Temporal bone fractures associated with temporohyoid osteoarthropathy have been recognized with CT, however, little information is available regarding these fractures. The aims of this retrospective analytical study were to assess the prevalence of these fractures and to describe the specific configurations and associated imaging and clinical features. Fracture of the temporal bone was identified with CT in 16 of 39 included horses. All fractures were unilateral, minimally displaced and extended through the ...
Use of a locking compression plate for equine proximal interphalangeal joint arthrodesis: 29 cases (2008-2014).
Journal of the American Veterinary Medical Association    November 20, 2018   Volume 253, Issue 11 1460-1466 doi: 10.2460/javma.253.11.1460
Sakai RR, Goodrich LR, Katzman SA, Moorman VJ, Leise BS, Kawcak CE, Galuppo LD.OBJECTIVE To describe clinical use of a locking compression plate (LCP) for proximal interphalangeal joint (PIPJ) arthrodesis in horses and compare outcomes for horses that underwent the procedure as treatment for fracture of the middle phalanx (P2) versus other causes. DESIGN Retrospective case series. ANIMALS 29 client-owned horses. PROCEDURES Medical records of 2 veterinary teaching hospitals from 2008 through 2014 were reviewed to identify horses that underwent PIPJ arthrodesis of 1 limb. Signalment, surgical, and outcome-related variables were recorded. Owners were contacted from 1 to 6 y...
A minimally invasive surgical technique for ureteral ostioplasty in two fillies with ureteral ectopia.
Journal of the American Veterinary Medical Association    November 20, 2018   Volume 253, Issue 11 1467-1472 doi: 10.2460/javma.253.11.1467
Jones ARE, Ragle CA.CASE DESCRIPTION 2 fillies, aged 3 months and 1 month, were examined because of urinary incontinence and urine scalding. CLINICAL FINDINGS In horse 1, ultrasonography did not reveal any structural abnormalities of the kidneys; however, unilateral ureteral ectopia was diagnosed cystoscopically. In horse 2, CT revealed bilateral nephropathy, bilateral distended ureters (up to 3.6 cm in diameter), and bilateral ureteral ectopia. Cystoscopy revealed intramural ureteral ectopia with abnormally caudally positioned ureteral ostia in both horses. TREATMENT AND OUTCOME Ureteral ostioplasty was performe...
Wound Management: Wounds with Special Challenges.
The Veterinary clinics of North America. Equine practice    November 19, 2018   Volume 34, Issue 3 511-538 doi: 10.1016/j.cveq.2018.07.003
Eggleston RB.Distal limb wounds in horses heal substantially different than trunk wounds, commonly resulting in exuberant granulation tissue and exposed and sequestered bone. Surgical intervention of severe rectovaginal lacerations in the mare should be delayed until the tissues have heeled and scar tissue has remodeled. Wounds resulting in severe hemorrhage require appropriate emergent fluid therapy and potentially transfusion therapy.
Nonhealing Wounds of the Equine Limb.
The Veterinary clinics of North America. Equine practice    November 19, 2018   Volume 34, Issue 3 539-555 doi: 10.1016/j.cveq.2018.07.007
Maher M, Kuebelbeck L.Nonhealing wounds present a common challenge to the equine practitioner. An underlying source of inflammation and infection is almost always present and needs to be resolved for healing to proceed. Wound débridement is the mainstay for this resolution. In addition, wound closure, wound dressings, and skin grafts can be used to achieve successful wound healing.
Exploring how end-of-life management is taught to Australasian veterinary students. Part 1: technical euthanasia.
The Veterinary record    November 19, 2018   Volume 183, Issue 22 691 doi: 10.1136/vr.104775
Littlewood KE, Beausoleil NJ, Stafford KJ, Stephens C, Collins T, Fawcett A, Hazel S, Lloyd JKF, Mallia C, Richards L, Wedler NK, Zito S.This descriptive study explored how end-of-life management was taught to students in all eight Australasian veterinary schools. A questionnaire-style interview guide was used by a representative at each university to conduct structured interviews with educators in a snowball sampling approach. Four categories of animals were addressed: livestock, equine, companion and avian/wildlife. This article focuses on the first part of the questionnaire: teaching the technical aspects of euthanasia. Euthanasia techniques were taught at more universities in clinical years than preclinical years. Clinical ...
Exercising upper respiratory videoendoscopic findings of 50 competition draught horses with abnormal respiratory noise and/or poor performance.
Equine veterinary journal    November 5, 2018   Volume 51, Issue 3 370-374 doi: 10.1111/evj.13026
Hackett ES, Leise BS.Upper respiratory tract (URT) endoscopy at rest is commonly used to evaluate competition draught horses with URT conditions. Overground endoscopy might be preferred for draught horse URT evaluation as it allows the horses to be driven with harness, overcheck and cart-load under similar conditions to those experienced in the show ring where airway conditions are most prominent. Objective: To describe the exercising URT findings of competition draught horses with abnormal respiratory noise and/or poor performance. Methods: Case series. Methods: Medical records of competition draught horses under...
Intrathecal Immunoglobulin for treatment of adult patients with tetanus: A randomized controlled 2×2 factorial trial.
Wellcome open research    November 5, 2018   Volume 3 58 doi: 10.12688/wellcomeopenres.14587.2
Loan HT, Yen LM, Kestelyn E, Hao NV, Thanh TT, Dung NTP, Turner HC, Geskus RB, Wolbers M, Tan LV, Van Doorn HR, Day NP, Wyncoll D, Hien TT....Despite long-standing availability of an effective vaccine, tetanus remains a significant problem in many countries. Outcome depends on access to mechanical ventilation and intensive care facilities and in settings where these are limited, mortality remains high. Administration of tetanus antitoxin by the intramuscular route is recommended treatment for tetanus, but as the tetanus toxin acts within the central nervous system, it has been suggested that intrathecal administration of antitoxin may be beneficial. Previous studies have indicated benefit, but with the exception of one small trial n...
Thoracic processi spinosi findings agree among subjective, semiquantitative, and modified semiquantitative scintigraphic image evaluation methods and partially agree with clinical findings in horses with and without thoracolumbar pain. van Zadelhoff C, Ehrle A, Merle R, Jahn W, Lischer C.Impinging processi spinosi in the equine thoracic spine are a common cause of poor performance in the horse. A modified semiquantitative scintigraphic image analysis has been proposed for the evaluation of equine processi spinosi. This technique showed a high inter- and intraobserver agreement when compared to subjective and semiquantitative image analysis. The aim of this retrospective, method comparison study was to evaluate the agreement of the modified semiquantitative scintigraphic image assessment with previous methods of interpretation and to compare these scintigraphic evaluation techn...
A prospective study on insect bite hypersensitivity in horses exported from Iceland into Switzerland.
Acta veterinaria Scandinavica    November 3, 2018   Volume 60, Issue 1 69 doi: 10.1186/s13028-018-0425-1
Torsteinsdottir S, Scheidegger S, Baselgia S, Jonsdottir S, Svansson V, Björnsdottir S, Marti E.Insect bite hypersensitivity (IBH) is an IgE-mediated dermatitis caused by bites of Culicoides spp., which occurs frequently in horses imported from Iceland to continental Europe. IBH does not occur in Iceland because Culicoides species that bite horses are not present. However, Simulium vittatum (S. vittatum) are found in Iceland. In Europe, blood basophils from IBH-affected horses release significantly more sulfidoleukotrienes (sLT) than those from healthy controls after in vitro stimulation with Culicoides nubeculosus (C. nubeculosus) and S. vittatum. Aims of the study were: (I) using the s...
Very long-term outcome of coronary covered stents: a report from the SCAAR registry. Harnek J, James SK, Lagerqvist B.Covered stents are mostly used for coronary perforations with a high risk of early adverse events; however, their long-term outcome is unknown. The aim of this study was to elucidate the short- and long-term outcome of patients treated with covered stents compared to all other stented patients. Results: The Swedish national registries from 2005-2017 disclosed 265 patients who had received 366 covered stents. Their outcomes were compared to all other stented patients (197,948) who had received 320,784 stents. Compared to regular stents, covered stents showed significant differences (p<0.001)...
Monitoring changes in distribution of pulmonary ventilation by functional electrical impedance tomography in anaesthetized ponies.
Veterinary anaesthesia and analgesia    October 28, 2018   Volume 46, Issue 2 200-208 doi: 10.1016/j.vaa.2018.09.048
Auer U, Schramel JP, Moens YP, Mosing M, Braun C.To assess changes in the distribution in pulmonary ventilation in anaesthetized ponies using electrical impedance tomography (EIT). Methods: Prospective experimental study. Methods: A group of eight adult pony geldings. Methods: General anaesthesia was induced and maintained using isoflurane in oxygen with volume-controlled ventilation [tidal volume (VT) (10 mL kg-1), respiratory rate (8-12 breaths minute-1)] to maintain end-tidal carbon dioxide between 35 and 40 mmHg (4.66-5.32 kPa). Regional distribution of ventilation was assessed with EIT (plane of fifth to sixth intercostal space) at 30, ...
Can heart rate variability parameters derived by a heart rate monitor differentiate between atrial fibrillation and sinus rhythm?
BMC veterinary research    October 25, 2018   Volume 14, Issue 1 320 doi: 10.1186/s12917-018-1650-6
Broux B, De Clercq D, Vera L, Ven S, Deprez P, Decloedt A, van Loon G.Heart rate variability (HRV) parameters, and especially RMSSD (root mean squared successive differences in RR interval), could distinguish atrial fibrillation (AF) from sinus rhythm(SR) in horses, as was demonstrated in a previous study. If heart rate monitors (HRM) automatically calculating RMSSD could also distinguish AF from SR, they would be useful for the monitoring of AF recurrence. The objective of the study was to assess whether RMSSD values obtained from a HRM can differentiate AF from SR in horses. Furthermore, the impact of artifact correction algorithms, integrated in the analyses ...
Investigation of an experimental infection model of equine coronavirus in adult horses.
Journal of veterinary internal medicine    October 24, 2018   Volume 32, Issue 6 2099-2104 doi: 10.1111/jvim.15318
Schaefer E, Harms C, Viner M, Barnum S, Pusterla N.Equine coronavirus (ECoV) is a recently reported enteric disease of adult horses. Natural infection by ECoV has been reported in adult horses worldwide, whereas experimental infection has only been reported in juvenile horses. An experimental infection model is needed to study the clinical presentation, laboratory abnormalities, and pathophysiological changes associated with ECoV. Objective: To investigate the clinical, hematologic, molecular, and serological features of adult horses experimentally infected with ECoV. Methods: Eight adult horses. Methods: Four horses were intragastrically infe...
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