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Topic:Clinical Findings

Clinical findings in horses encompass a range of observable signs and symptoms identified during veterinary examinations that contribute to diagnosing and managing equine health conditions. These findings can include physical observations, such as changes in behavior, posture, or gait, as well as physiological measurements like heart rate, respiratory rate, and temperature. Diagnostics may also involve laboratory tests, imaging, and other diagnostic procedures to assess organ function and detect abnormalities. Recognizing and interpreting clinical findings are essential components of veterinary practice, aiding in the identification of diseases, monitoring treatment progress, and guiding therapeutic interventions. This page brings together peer-reviewed research studies and scholarly articles that explore the methodologies, interpretations, and implications of clinical findings in the context of equine health care.
Equine keratomycoses in California from 1987 to 2010 (47 cases).
Equine veterinary journal    September 4, 2012   Volume 45, Issue 3 361-366 doi: 10.1111/j.2042-3306.2012.00623.x
Reed Z, Thomasy SM, Good KL, Maggs DJ, Magdesian KG, Pusterla N, Hollingsworth SR.Equine keratomycosis in the western USA has received little study, probably owing to its low prevalence. Objective: To determine clinical features, predominant fungal isolates, treatment modalities and outcomes of horses with keratomycosis in California and compare these with results from different geographic regions. Methods: Records of horses presented to the University of California-Davis Veterinary Medical Teaching Hospital (UCD-VMTH) with confirmed keratomycosis between 1987 and 2010 were reviewed for this retrospective study. Information retrieved from the record included background, oph...
A retrospective study of horses investigated for weight loss despite a good appetite (2002-2011).
Equine veterinary journal    September 4, 2012   Volume 45, Issue 3 340-345 doi: 10.1111/j.2042-3306.2012.00624.x
Metcalfe LV, More SJ, Duggan V, Katz LM.Weight loss despite a good appetite is a frequent diagnostic challenge for equine veterinarians; however, there are few objective reports and little descriptive information regarding risk factors and prognostic indicators. Objective: To provide a descriptive epidemiological analysis of horses evaluated for weight loss despite a good appetite and evaluate relationships between historical and clinicopathological findings and final outcome (survival vs. nonsurvival) to identify risk factors and prognostic indicators. Methods: Medical records of horses referred for investigation of weight loss des...
Ocular abnormalities in healthy Standardbred foals.
Veterinary ophthalmology    September 3, 2012   Volume 16, Issue 4 245-250 doi: 10.1111/j.1463-5224.2012.01063.x
Barsotti G, Sgorbini M, Marmorini P, Corazza M.To determine the prevalence and describe ocular abnormalities in healthy Standardbred foals within 48 h of birth. Methods: One hundred and two neonatal foals. Methods: All foals had an unassisted delivery. On the basis of physical examination and the results of hematological and biochemical parameters, all foals were unaffected by systemic diseases. A complete ophthalmic examination was performed within 48 h of birth. Foals with ocular hemorrhages were re-examined weekly until the abnormalities were resolved. Results: 65/102 (63.7%) foals did not show ocular abnormalities, while in 37/102 (36....
Eastern equine encephalitis: MRI findings in two patients.
Medicine and health, Rhode Island    August 30, 2012   Volume 95, Issue 7 227-229 
Ethier M, Rogg J.No abstract available
Extensive myenteric ganglionitis in a case of equine chronic intestinal pseudo-obstruction associated with EHV-1 infection.
Journal of comparative pathology    August 27, 2012   Volume 148, Issue 4 289-293 doi: 10.1016/j.jcpa.2012.07.004
Pavone S, Sforna M, Gialletti R, Prato S, Marenzoni ML, Mandara MT.A 7-year-old male trotter horse with a history of recurrent colic displayed clinical findings consistent with chronic intestinal pseudo-obstruction (CIP). At laparotomy, an impaction of the descending colon associated with marked atrophy of the right dorsal colon was found. The horse was humanely destroyed and tissues collected at necropsy examination revealed diffuse enteric ganglionitis comprising an infiltrate of CD3(+) T lymphocytes and plasma cells. At all levels of the intestinal tract the number of myenteric ganglia and of normal ganglion cells was decreased significantly. There were ch...
Liver lobe torsion in six horses.
Journal of the American Veterinary Medical Association    August 25, 2012   Volume 241, Issue 5 615-620 doi: 10.2460/javma.241.5.615
Tennent-Brown BS, Mudge MC, Hardy J, Whelchel DD, Freeman DE, Fischer AT.6 horses were determined to have torsion of a liver lobe at 4 referral institutions over a 21-year period. Results: Clinical findings were nonspecific but often included signs of marked inflammation. Two of the 6 horses were examined because of colic, and 2 were assessed because of peritonitis that failed to respond to treatment; the remaining 2 horses were examined because of nonspecific clinical signs that included inappetence, lethargy, and weight loss. The results of laboratory tests were widely variable, and values for liver enzyme activities were typically within reference limits or only...
Pyogranulomatous lesion causing neurological signs localised to the sacral region in a horse.
Australian veterinary journal    August 23, 2012   Volume 90, Issue 10 392-394 doi: 10.1111/j.1751-0813.2012.00982.x
Cudmore LA, Groenendyk JC, Hodge P, Church S.This case report describes neurological signs associated with a pyogranulomatous lesion within the sacral vertebral canal of a horse. The clinical findings included urinary overflow incontinence and reduced anal, perianal and tail tone. The horse failed to respond to medical management and a guarded prognosis for return to athletic performance initiated the decision for euthanasia.
Right dorsal displacement of the large colon as a cause of surgical colic in three foals in New Zealand.
New Zealand veterinary journal    August 21, 2012   Volume 60, Issue 6 360-364 doi: 10.1080/00480169.2012.694406
Hennessy SE, Fraser BS.Over a 3-year period between July 2008 and July 2011, 10 exploratory laparotomies were performed on foals in a Waikato referral facility in New Zealand. Results: Right dorsal displacement of the large colon (RDDLC) was identified during four exploratory laparotomies in three foals that presented for mild-to-moderate colic that was non-responsive to medical management. One foal required a repeat laparotomy 7 weeks post initial surgery, and RDDLC was again diagnosed. Methods: Right dorsal displacement of the large colon in foals. Conclusions: Further investigation may identify risk factors or ma...
Identification of predictors of Salmonella shedding in adult horses presented for acute colic.
Journal of veterinary internal medicine    August 9, 2012   Volume 26, Issue 5 1177-1185 doi: 10.1111/j.1939-1676.2012.00984.x
Dallap Schaer BL, Aceto H, Caruso MA, Brace MA.Colic has been associated with shedding of Salmonella. Horses with salmonellosis typically develop diarrhea, fever, and leukopenia. Overlooking additional predictors may result in failure to detect shedding horses and increase environmental contamination. Objective: Evaluate associations between signalment and clinicopathologic data during early hospitalization and Salmonella shedding in horses treated for acute colic. Methods: Horses with acute colic admitted to a referral hospital. A total of 59 horses shedding Salmonella compared to 108 Salmonella-negative horses. Methods: Retrospective cas...
Validation of an equine inertial measurement unit system in clinically normal horses during walking and trotting.
American journal of veterinary research    August 2, 2012   Volume 73, Issue 8 1160-1170 doi: 10.2460/ajvr.73.8.1160
Moorman VJ, Reiser RF, McIlwraith CW, Kawcak CE.To validate an equine inertial measurement unit (IMU) system rigidly attached to a hoof against a 3-D optical kinematics system in horses during walking and trotting. Methods: 5 clinically normal horses. Methods: 5 swing phases of the hooves of the right forelimb and hind limb were collected via both 3-D optical and IMU systems from 5 horses during walking and trotting. Linear and angular positions, velocities, and accelerations were compared between the 2 systems. Results: Of the 55 variables compared between the 2 systems, 25 had high correlations (r > 0.8) and 18 had moderate correlation...
Equine distal limb wounds: new and emerging treatments.
Compendium (Yardley, PA)    August 1, 2012   Volume 34, Issue 7 E5 
Alford CG, Caldwell FJ, Hanson R.Distal limb wounds occur commonly in horses, and treatment can be frustrating for owners and veterinarians. Caring for these wounds is often very expensive, labor intensive, and prolonged. Many commercial products and clinical techniques have been developed to help treat these wounds. Healing of these wounds depends on many factors. With proper wound evaluation and treatment, affected horses can return to function sooner than in the past.
Allele copy number and underlying pathology are associated with subclinical severity in equine type 1 polysaccharide storage myopathy (PSSM1).
PloS one    July 31, 2012   Volume 7, Issue 7 e42317 doi: 10.1371/journal.pone.0042317
Naylor RJ, Livesey L, Schumacher J, Henke N, Massey C, Brock KV, Fernandez-Fuente M, Piercy RJ.Equine type 1 polysaccharide storage myopathy (PSSM1), a common glycogenosis associated with an R309H founder mutation in the glycogen synthase 1 gene (GYS1), shares pathological features with several human myopathies. In common with related human disorders, the pathogenesis remains unclear in particular, the marked phenotypic variability between affected animals. Given that affected animals accumulate glycogen and alpha-crystalline polysaccharide within their muscles, it is possible that physical disruption associated with the presence of this material could exacerbate the phenotype. The aim ...
Tissue Doppler imaging and 2-dimensional speckle tracking of left ventricular function in horses exposed to lasalocid.
Journal of veterinary internal medicine    July 28, 2012   Volume 26, Issue 5 1209-1216 doi: 10.1111/j.1939-1676.2012.00972.x
Decloedt A, Verheyen T, Sys S, De Clercq D, van Loon G.Tissue Doppler imaging (TDI) and 2-dimensional speckle tracking (2DST) can quantify left ventricular (LV) function in horses. Objective: To evaluate LV function by TDI and 2DST in horses with myocardial dysfunction after accidental ionophore intoxication. Methods: Sixty-seven horses exposed to lasalocid in feed. Methods: Prospective study. Horses were included in the study if a full cardiac examination was performed, consisting of determination of cardiac troponin I (cTnI), electrocardiography, and echocardiography. By TDI, radial systolic velocity and strain were measured. By 2DST, circumfere...
Resolution of sustained narrow complex ventricular tachycardia and tachycardia-induced cardiomyopathy in a Quarter Horse following quinidine therapy.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology    July 26, 2012   Volume 14, Issue 3 445-451 doi: 10.1016/j.jvc.2012.05.004
Stern JA, Doreste YR, Barnett S, Lahmers SM, Baumwart RD, Seino KK, Bonagura JD.Sustained narrow-QRS tachycardia of three months duration and left ventricular systolic dysfunction were identified in a fifteen-year-old Quarter Horse. No underlying cause for the tachyarrhythmia was found and no predisposing structural cardiac lesions were evident by echocardiography. Intravenous diltiazem and lidocaine were administered without achieving successful conversion of the arrhythmia. Oral quinidine therapy converted the tachyarrhythmia to sinus rhythm. Ventricular systolic dysfunction and chamber dilatation subsequently resolved. As with other species, echocardiographic features ...
Farriery for the hoof with a sheared heel.
The Veterinary clinics of North America. Equine practice    July 18, 2012   Volume 28, Issue 2 381-392 doi: 10.1016/j.cveq.2012.05.002
O'Grady SE.Sheared heels develop as an adaptation-distortion of the hoof capsule as a result of an abnormal strike and loading pattern of the foot, which is generally a consequence of limb conformation. The growth rate around the circumference of the hoof should be approximately uniform, but regional disturbances in growth rate can occur to either increase or decrease growth. The primary conformational trait that is observed in horses that develop sheared heels is a rotational deformity of the distal limb and a narrow chest. Farriery is directed toward improving the hoof capsule distortion and decreasing...
Equine imaging: the framework for applying therapeutic farriery.
The Veterinary clinics of North America. Equine practice    July 18, 2012   Volume 28, Issue 2 293-312 doi: 10.1016/j.cveq.2012.05.001
Eggleston RB.Radiographic evaluation of a horse's foot gives tremendous insight into the relationship between the structures within the foot and between the foot and distal limb. The information gained from a radiographic study is highly dependent on the quality of the radiographs. A systematic approach should be taken when planning a radiographic study of the foot. Taking the time to examine the foot and prepare it properly will avoid the need, risk, and expense of repeating images and will improve the quality and therefore the interpretation of your radiographic images. When evaluating the foot for podia...
Hepatoencephalopathy syndrome due to Cassia occidentalis (Leguminosae, Caesalpinioideae) seed ingestion in horses.
Equine veterinary journal    July 12, 2012   Volume 45, Issue 2 240-244 doi: 10.1111/j.2042-3306.2012.00599.x
Oliveira-Filho JP, Cagnini DQ, Badial PR, Pessoa MA, Del Piero F, Borges AS.Cassia occidentalis is a bush from the Leguminosae family, subfamily Caesalpinoideae, and is a toxic plant of veterinary interest due to the occasional contamination of animal rations. This report describes the clinical and histopathological findings of an outbreak of C. occidentalis poisoning in horses. Twenty mares were poisoned after consuming ground corn contaminated with 8% of C. occidentalis seeds. Of the 20 animals affected, 12 died: 8 mares were found dead, 2 died 6 h after the onset of clinical signs compatible with hepatic encephalopathy and the 2 other animals were subjected to euth...
Hydrallantois in a recipient mare.
The Veterinary record    July 11, 2012   Volume 171, Issue 7 177 doi: 10.1136/vr.100917
Byrne Elliott CR, Mitchell A.No abstract available
Periodontal biomechanics: finite element simulations of closing stroke and power stroke in equine cheek teeth.
BMC veterinary research    July 11, 2012   Volume 8 60 doi: 10.1186/1746-6148-8-60
Cordes V, Lüpke M, Gardemin M, Seifert H, Staszyk C.In equine dentistry periodontal diseases, especially periapical inflammation, are frequently occurring problems. Anachoresis is believed to be the most common cause for the development of such disorders. Nevertheless, there is still no substantiated explanation why settlement of pathogen microorganisms occurs in equine periodontal tissues. It is expected that excessive strains and stresses occurring in the periodontal ligament (PDL) during the horse's chewing cycle might be a predisposing factor. In this study this assumption was examined by finite element (FE) analyses on virtual 3-D models o...
Intra and postoperative assessment of re-sterilised Ligasure Atlas for orchidectomies in horses: clinical study.
The Veterinary record    July 10, 2012   Volume 171, Issue 4 98 doi: 10.1136/vr.100601
Gracia-Calvo LA, Martín-Cuervo M, Jiménez J, Vieítez V, Durán ME, Argüelles D, Ezquerra LJ.Horses (n=35) underwent orchidectomy in a single institution with a re-sterilised LSA as sole means of haemostasis. During the surgery, the gross quality of the seal, the stickiness of the forceps to the tissues, bleeding/oozing from the stump and the need for a subsequent application in already severed spermatic cord were assessed for haemostasis quality. After surgery, physical parameters (appearance of the mucous membranes, quality of the peripheral pulse, heart rate, respiratory rate, rectal temperature and blood dripping from the incisions), haematology or packed cell volume and total pro...
Ocular manifestations of a metastatic adenocarcinoma in a horse.
Veterinary ophthalmology    July 5, 2012   Volume 16, Issue 3 214-218 doi: 10.1111/j.1463-5224.2012.01042.x
Matheis FL, Birkmann K, Ruetten M, Pot SA, Spiess BM.A 10-year-old German Warmblood gelding was referred to the Equine Department of the Vetsuisse Faculty, University of Zurich, Switzerland, for an iris mass OD, lethargy, intermittent fever, and coughing. Ophthalmic examination revealed a 7 × 9 mm raised, fleshy, whitish to pinkish, vascularized iris mass at the 2 o`clock position OD. Fundic examination showed multifocal round, brown to black, slightly raised lesions with indistinct margins and a surrounding hyperreflective zone OU. Physical examination revealed a temperature of 39.2 °C, sinus tachycardia, preputial and ventral edema, and an e...
Direct intra-abdominal pressures and abdominal perfusion pressures in unsedated normal horses.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)    July 5, 2012   Volume 22, Issue 4 441-446 doi: 10.1111/j.1476-4431.2012.00774.x
Hurcombe SD, Scott VH.To determine whether direct intra-abdominal pressures (IAP) and calculated direct abdominal perfusion pressures (APP) are location dependent within the abdomen of standing horses. We hypothesize that IAP will be increased and calculated APP will be decreased at a ventral abdominal location (V) when compared to values obtained from the left (LFl) or right flank (RFl). Methods: Prospective experimental design. Methods: University-based equine research facility. Methods: Seven healthy adult horses, 4 geldings and 3 mares. Methods: Measurements of direct IAP obtained from the RFl, LFl, and V locat...
Removal of a nasogastric tube fragment from the stomach of a standing horse.
The Canadian veterinary journal = La revue veterinaire canadienne    July 4, 2012   Volume 53, Issue 1 83-85 
Cribb NC, Kenney DG, Reid-Burke R.An 82-cm fragment of nasogastric tube was removed from the stomach of an adult horse under standing sedation by use of an endoscope and electrocautery snare. This is the first report of successful non-surgical removal of a nasogastric tube fragment from the stomach of a horse. Un fragment de 82 cm d’un tube naso-gastrique a été enlevé de l’estomac d’un cheval adulte sous sédation se tenant debout en utilisant un endoscope et une anse de galvanocautérisation. Il s’agit du premier rapport de l’enlèvement non chirurgical d’un fragment de tube naso-gastrique de l’estomac d’u...
Association between radiographic pattern and outcome in foals with pneumonia caused by Rhodococcus equi. Giguère S, Roberts GD.Our objective was to characterize the association between types of radiographic findings and outcome in foals with pneumonia caused by Rhodococcus equi. Admission lateral thoracic radiographs of 62 foals with culture-confirmed R. equi pneumonia were reviewed retrospectively. A scoring system was developed to individually assess the severity of alveolar pattern, interstitial pattern, tracheobronchial lymphadenopathy, pleural effusion, and the number of nodular opacities and cavitary lesions. Individual scores were added to obtain a total radiographic score ranging from 0 (normal) to 22. Forty-t...
Clinical significance and prognosis of deep digital flexor tendinopathy assessed over time using MRI. Vanel M, Olive J, Gold S, Mitchell RD, Walker L.Deep digital flexor (DDF) tendinopathy is one of the most frequent causes of foot lameness and the prognosis is guarded. The progress of lesion healing may be followed by magnetic resonance (MR) imaging to formulate a prognosis and to adapt the rehabilitation program. We assessed the correlation of outcome with total tendon damage and temporal resolution of MR abnormalities. Images from 34 horses with DDF tendinopathy that had undergone at least two low-field standing MR examinations of the foot (mean 2.5 ± 1.3 times) were reviewed. No horse having a T1-GRE hyperintense lesion over 30 mm in l...
Magnetic resonance imaging of navicular bursa adhesions. Holowinski ME, Solano M, Maranda L, García-López JM.Adhesions occur in the navicular bursa between the deep digital flexor tendon (DDFT) and other structures. Our objectives were to describe the appearance of navicular bursa adhesions on high-field magnetic resonance (MR) images, to compare these findings to findings at navicular bursoscopy, and to determine the prevalence of lesions in the remainder of the podotrochlear apparatus. Sixteen forelimbs from 14 horses that underwent MR imaging and navicular bursoscopy were evaluated. Adhesions were considered type 1 when characterized by a discontinuity in the navicular bursa fluid signal between t...
Ruptured urinary bladder in a horse.
Veterinary anaesthesia and analgesia    June 22, 2012   Volume 39, Issue 5 557-558 doi: 10.1111/j.1467-2995.2012.00742.x
Quinn CT, Carmalt JL.No abstract available
Nephrogenic diabetes insipidus in a 14-year-old gelding.
New Zealand veterinary journal    June 21, 2012   Volume 60, Issue 4 254-257 doi: 10.1080/00480169.2012.669723
Morgan RA, Malalana F, McGowan CM.A 14-year-old Cleveland Bay cross gelding was presented with severe urinary incontinence that had been present for 1 year, and chronic polydipsia and polyuria over 4 years. Water intake had been recorded as 240 L over a 24-hour period. Results: The horse had marked urinary incontinence and polyuria and polydipsia. The urine was markedly hyposthenuric, but no abnormalities on urinalysis were detected. There were no other abnormal clinical or neurological signs. Haematological and serum biochemical examinations showed no abnormalities and ultrasonographic and endoscopic examination of the urinar...
Clinical, hematologic, and electrolyte changes with 0.9% sodium chloride or acetated fluids in endurance horses.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)    June 19, 2012   Volume 22, Issue 3 327-331 doi: 10.1111/j.1476-4431.2012.00745.x
Fielding CL, Magdesian KG, Meier CA, Rhodes DM.To describe the clinical and laboratory changes associated with the use of IV0.9% sodium chloride and a commercially available acetated fluid (CAF) to treat endurance horses requiring emergency medical treatment. Methods: Randomized, controlled clinical trial from 2007 to 2010. Methods: Emergency treatment centers of the Western States 100-mile (220 km) endurance ride. Methods: Twelve horses requiring emergency medical treatment in the form of IVfluids completed the study. Methods: Horses were assigned to either the 0.9% sodium chloride group (6 horses) or CAF group (6 horses) and received a t...
Prevalence and some clinical characteristics of equine cheek teeth diastemata in 471 horses examined in a UK first-opinion equine practice (2008 to 2009).
The Veterinary record    June 15, 2012   Volume 171, Issue 2 44 doi: 10.1136/vr.100829
Walker H, Chinn E, Holmes S, Barwise-Munro L, Robertson V, Mould R, Bradley S, Shaw DJ, Dixon PM.Cheek teeth (CT) diastemata are now recognised as a clinically significant equine disorder, but their prevalence in the general equine population is unknown. There is also limited information on the signalment of affected horses; the more commonly affected Triadan sites; and the shape and clinical characteristics of CT diastemata. During the 12-month study period (2008 to 2009), standardised records were obtained during routine dental examinations performed by five veterinarians in a first-opinion equine practice. Cheek teeth diastemata were identified in 49.9 per cent of all horses (n=471) of...
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