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Topic:Clinical Symptoms

Clinical symptoms in horses encompass a range of observable signs that may indicate underlying health issues, such as disease, injury, or physiological stress. These symptoms can vary widely depending on the condition and may include changes in behavior, appetite, respiratory patterns, or physical appearance. Common clinical symptoms in horses include lameness, colic, coughing, nasal discharge, and changes in body temperature or heart rate. Identifying and interpreting these symptoms is an essential aspect of equine veterinary practice, as they provide critical information for diagnosis and management of health conditions. This page compiles peer-reviewed research studies and scholarly articles that explore the identification, assessment, and implications of clinical symptoms in equine health management.
Arthroscopic removal of palmar intermediate carpal bone fracture fragments in four horses using a transthecal approach through the carpal flexor tendon sheath.
Veterinary surgery : VS    April 11, 2022   Volume 51, Issue 6 929-939 doi: 10.1111/vsu.13813
Hewitt-Dedman CL, O'Neill HD, Bladon BM.To describe the removal of palmar intermediate carpal bone (ICB) fracture fragments using a transthecal approach through the carpal flexor tendon sheath. Methods: Case series. Methods: Four horses with fractures of the palmar aspect of the ICB. Methods: Two horses were injured when falling and two during recovery from general anesthesia. Three horses underwent MRI to supplement conventional imaging. Three horses had concurrent fractures of the radial and/or accessory carpal bones. Conventional proximolateral carpal sheath arthroscope and instrument portals were used, supplemented with a medial...
Chronic Renal Failure-Causes, Clinical Findings, Treatments and Prognosis.
The Veterinary clinics of North America. Equine practice    April 3, 2022   Volume 38, Issue 1 25-46 doi: 10.1016/j.cveq.2021.11.003
Olsen E, van Galen G.Chronic kidney disease (CKD) is rare in horses with an overall prevalence reported to be 0.12%. There is often a continuum from Acute Kidney Injury (AKI) to CKD, and patients with CKD may be predisposed to episodes of AKI. The most common clinical signs are non-specific with weight loss, polyuria/polydipsia and ventral edema. Less common clinical signs are poor appetite and performance, dull hair coat, oral ulcerations, gastro-intestinal ulceration, gingivitis, dental tartar and diarrhea. Rarely, horses may develop forebrain signs. Creatinine increases when at least 2/3 of kidney function have...
Predictors of laminitis development in a cohort of nonlaminitic ponies.
Equine veterinary journal    April 1, 2022   Volume 55, Issue 1 12-23 doi: 10.1111/evj.13572
Knowles EJ, Elliott J, Harris PA, Chang YM, Menzies-Gow NJ.Quantifying risk factors for laminitis development requires improvement. Objective: To identify the most useful physical examination, metabolic and management factors to predict laminitis development in client-owned, nonlaminitic ponies. Methods: Prospective cohort study. Methods: Physical examination, metabolic and management data were collected from a pony cohort 6 monthly for up to 4 years. Ponies were monitored for the development of laminitis. Metabolic data included basal plasma concentrations of ACTH ([ACTH]), adiponectin ([adiponectin]), triglycerides and glucose. Serum insulin concen...
Gastrointestinal biopsy in the horse: overview of collection, interpretation, and applications. Hostetter JM, Uzal FA.Evaluation of gastrointestinal (GI) biopsies is a multistep process that includes reviewing an appropriate history, determining sample quality, and evaluating histologic sections. Selected diagnostic parameters that, in combination with intestinal histopathology, can be useful to localize disease to the intestinal tract in the horse include hypoproteinemia and hypoalbuminemia, ultrasound evidence of increased thickness of the small intestinal wall, and alterations in glucose or D-xylose absorption tests. Biopsies may be acquired either endoscopically, or via laparoscopy or standing flank incis...
Perioperative lung ultrasonography in healthy horses undergoing general anesthesia for elective surgery.
Journal of veterinary internal medicine    March 24, 2022   Volume 36, Issue 3 1160-1172 doi: 10.1111/jvim.16408
Ribonnet C, Palmers K, Saegerman C, Vanderperren K, van Galen G.Lung ultrasound (LUS) is poorly evaluated in horses, especially perioperatively. Objective: (1) Describe LUS findings in healthy horses before and after general anesthesia (GA), (2) evaluate if GA induces ultrasonographic changes in healthy horses, (3) suggest a LUS scoring system, (4) identify horse variables that are associated to LUS changes after anesthesia. Methods: Twenty-five healthy adult horses undergoing elective surgery. Methods: Prospective hypothesis-driven observational study. LUS findings were recorded before anesthesia, 5 minutes in recovery, 15 minutes, 2H, 3H, 4H, 6H, and ...
Anesthesia Case of the Month.
Journal of the American Veterinary Medical Association    March 16, 2022   Volume 260, Issue 12 1-4 doi: 10.2460/javma.21.07.0327
Bartholomew KJ, Loeber SJ, Johnson RA.No abstract available
Imaging of the Urinary Tract.
The Veterinary clinics of North America. Equine practice    March 10, 2022   Volume 38, Issue 1 123-140 doi: 10.1016/j.cveq.2021.11.009
Cercone M.This article provides a comprehensive review of imaging techniques used to evaluate the equine urinary tract. This overview includes officially recognized modalities and new applications reported in the most current literature. Technical aspects and indications for use of endoscopy and ultrasonography are highlighted. Normal endoscopic and ultrasonographic appearance of the upper and lower urinary tract is described, with characterization of common abnormalities found in patients with hematuria, stranguria, and renal failure. Visual examples of several pathologic conditions from clinical cases...
Urinary Tract Disorders of Foals.
The Veterinary clinics of North America. Equine practice    March 10, 2022   Volume 38, Issue 1 47-56 doi: 10.1016/j.cveq.2021.11.004
DeNotta SL.Urinary disease in the neonatal period can occur with primary congenital renal defects or as a secondary consequence of birth trauma, ischemic injury, nephrotoxic medications, or systemic illness. This article reviews the clinical evaluation of the urinary system in foals and highlights diagnostic and therapeutic features of the most commonly encountered urinary disorders of the equine neonatal patient.
Metabolic Disorders Associated with Renal Disease in Horses.
The Veterinary clinics of North America. Equine practice    March 10, 2022   Volume 38, Issue 1 109-122 doi: 10.1016/j.cveq.2021.11.008
Mullen KR.This article overviews metabolic disorders associated with renal disease. Included is a discussion of the pathophysiology, clinical signs, and treatment of hyperchloremic metabolic acidosis associated with renal tubular acidosis. Conditions affecting the central nervous system including uremic encephalopathy and hyponatremic encephalopathy secondary to renal disease are presented. Finally, a discussion of the unique features of calcium and phosphorus homeostasis in horses is provided with special emphasis on a recently described syndrome of calcinosis and calciphylaxis of unknown etiology.
Full-thickness endotracheal tube defect resulting in an anaesthetic circuit leak.
Equine veterinary journal    March 10, 2022   Volume 55, Issue 1 66-68 doi: 10.1111/evj.13569
Miller L, Lord S.Loss of endotracheal tube (ETT) integrity secondary to dental damage is reported in the human literature. Objective: To describe this problem in equine anaesthesia. Methods: Case report. Conclusions: An 18-year-old Standardbred gelding presented out of hours with colic signs. Findings on clinical examination and pain refractory to analgesia meant that exploratory laparotomy was elected for. Prior to general anaesthesia (GA) leak testing of the anaesthetic machine was performed and the pilot balloon of the endotracheal tube (ETT) was inflated to confirm cuff integrity. Intermittent-positive pre...
What Is Your Diagnosis?
Journal of the American Veterinary Medical Association    March 8, 2022   Volume 260, Issue 10 1167-1169 doi: 10.2460/javma.20.09.0512
Jucker JM, Johnson LC, Young AA, Yaxley PE, Hostnik ET, Tinga S.No abstract available
Critically important antimicrobials are frequently used on equine racetracks.
Journal of the American Veterinary Medical Association    March 3, 2022   Volume 260, Issue 7 774-779 doi: 10.2460/javma.22.01.0022
Dorph K, Haughan J, Robinson M, Redding LE.To characterize antimicrobial use on four racetracks in the eastern US during the peak racing 2017-2018 seasons. Handwritten daily treatment sheets provided by attending veterinarians who listed treatments administered to horses stabled at the racetrack were obtained. Information contained in the treatment sheets included the date, name of the horse and its trainer, type of treatment, and a brief (usually 1-word) indication for treatment. The handwritten data listed on the racetrack treatment sheets were manually transcribed and analyzed. A total of 2,684 antimicrobial prescriptions were recor...
Rib fractures in adult horses as a cause of poor performance; diagnosis, treatment and outcome in 73 horses.
Equine veterinary journal    March 1, 2022   Volume 55, Issue 1 59-65 doi: 10.1111/evj.13566
Hall S, Smith R, Ramzan PHL, Head M, Robinson N, Parker R.Rib fractures in adult horses are poorly documented. Objective: To describe the presenting signs, diagnosis, treatment and outcome of horses diagnosed with rib fracture. Methods: Retrospective case series. Methods: The clinical records and diagnostic images of all adult horses diagnosed with a rib fracture at three referral centres over a 15-year period were reviewed. Results: Seventy-three horses met the inclusion criteria. Horses presented due to either resistance to ridden work and poor performance (n = 41), lameness (n = 21) or trauma (n = 7). In four horses, the presenting complaint...
Three-dimensional printed surgical guides for keratoma removal in horses using computed tomography or magnetic resonance imaging-based segmentation.
Veterinary surgery : VS    February 28, 2022   Volume 51 Suppl 1 O43-O52 doi: 10.1111/vsu.13786
Biedrzycki AH, Morton AJ, Perez-Jimenez EE, Elane GL, Roe HA, Trolinger-Meadows KD.To report the technique, surgical approach, and postoperative features in horses treated via a 3-dimensional (3D) printed guide-assisted keratoma resection created using computed tomography (CT) or magnetic resonance imaging (MRI)-based segmentation. Methods: Five client-owned horses. Methods: Short case series. Methods: Horses were placed under general anesthesia for imaging (CT and MRI) and underwent a second anesthesia for surgery. Two horses had guides created from CT-based imaging, 3 horses had guides created from MRI. Various sized nonarbored hole saws were used to create accurate and pr...
What Is Your Diagnosis?
Journal of the American Veterinary Medical Association    February 28, 2022   Volume 259, Issue S1 1-3 doi: 10.2460/javma.20.08.0451
Hsuan LY, Lipitz L, Sage JE.In collaboration with the American College of Veterinary Radiology.
Photodermatitis and ocular changes in nine horses after ingestion of wild parsnip (pastinaca sativa).
BMC veterinary research    February 26, 2022   Volume 18, Issue 1 80 doi: 10.1186/s12917-022-03162-2
Winter JC, Thieme K, Eule JC, Saliu EM, Kershaw O, Gehlen H.Primary photosensitization rarely occurs in horses and can easily be misinterpreted. Descriptions of the disease in horses after ingestion of parsnip are lacking. The aim of this case series was to describe the dermatological and ocular changes due to photosensitization and to raise awareness of parsnip being a possible aetiologic agent. Methods: Nine horses from three different stables in Berlin and Brandenburg, Germany, presented variable degrees of erythema, scaling, crusting and necrosis of unpigmented skin at the head and prepuce. Horses were of different breeds with a median age of 15 ...
An Exploratory Study on Vectorcardiographic Identification of the Site of Origin of Focally Induced Premature Depolarizations in Horses, Part I: The Atria.
Animals : an open access journal from MDPI    February 23, 2022   Volume 12, Issue 5 549 doi: 10.3390/ani12050549
Van Steenkiste G, Delhaas T, Hermans B, Vera L, Decloedt A, van Loon G.In human cardiology, the anatomical origin of atrial premature depolarizations (APDs) is derived from P wave characteristics on a 12-lead electrocardiogram (ECG) and from vectorcardiography (VCG). The objective of this study is to differentiate between anatomical locations of APDs and to differentiate APDs from sinus rhythm (SR) based upon VCG characteristics in seven horses without cardiovascular disease. A 12-lead ECG was recorded under general anaesthesia while endomyocardial atrial pacing was performed (800−1000 ms cycle length) at the left atrial free wall and septum, right atrial free ...
An Exploratory Study on Vectorcardiographic Identification of the Site of Origin of Focally Induced Premature Depolarizations in Horses, Part II: The Ventricles.
Animals : an open access journal from MDPI    February 23, 2022   Volume 12, Issue 5 doi: 10.3390/ani12050550
Van Steenkiste G, Delhaas T, Hermans B, Vera L, Decloedt A, van Loon G.In human cardiology, the anatomical origin of ventricular premature depolarizations (VPDs) is determined by the characteristics of a 12-lead electrocardiogram (ECG). Former studies in horses had contradictory results regarding the diagnostic value of the 12-lead ECG and vectorcardiography (VCG), which results were attributed to the different cardiac conduction system in this species. The objective of this study was to determine if the anatomical origin of pacing-induced VPDs could be differentiated in horses based upon VCG characteristics. A 12-lead ECG was recorded in seven horses under gener...
An Analysis of Risk Factors for a Fracture or Luxation in Recovery From General Anesthesia in Horses: A Single Centre Study☆.
Journal of equine veterinary science    February 23, 2022   Volume 112 103914 doi: 10.1016/j.jevs.2022.103914
Bennell AJ, Wright RJH, Malalana F, Senior JM.Catastrophic fractures or luxations (FoL) sustained during recovery from general anesthesia are a significant cause of mortality during equine anesthesia. There is a lack of evidence regarding potential risk factors for a FoL occurring in the immediate anesthetic recovery period. A single center, retrospective, case-matched study was performed to identify risk factors for sustaining a catastrophic FoL during recovery from general anesthesia. Clinical data were obtained for horses which sustained a catastrophic FoL when recovering from general anesthesia from January 2011 to June 2020 in a sing...
Flow-controlled expiration improves respiratory mechanics, ventilation, and gas exchange in anesthetized horses.
American journal of veterinary research    February 16, 2022   Volume 83, Issue 5 393-398 doi: 10.2460/ajvr.21.10.0158
Hopster K, Hurcombe SD, Simpson K, VanderBroek AR, Driessen B.Mechanical ventilation is usually achieved by active lung inflation during inspiration and passive lung emptying during expiration. By contrast, flow-controlled expiration (FLEX) ventilation actively reduces the rate of lung emptying by causing linear gas flow throughout the expiratory phase. Our aim was to evaluate the effects of FLEX on lung compliance and gas exchange in anesthetized horses in dorsal recumbency. Methods: 8 healthy horses. Methods: All animals were anesthetized twice and either ventilated beginning with FLEX or conventional volume-controlled ventilation in a randomized, cros...
Studies on Age-Related Changes in Equine Cheek Teeth Angulation and Dental Drift.
Frontiers in veterinary science    February 15, 2022   Volume 8 804061 doi: 10.3389/fvets.2021.804061
Liuti T, Daniel CR, Dixon PM, Reardon RJM.Cheek teeth (second through fourth premolars and first through third molars) diastema is a common and painful equine disorder caused by the absence of effective tight interdental contact between these teeth. Limited objective information is available on the angulation of equine cheek teeth that control dental drift or on mesial or distal equine cheek teeth drift that should normally prevent this disorder. Objective: To measure the angulation of the mesial and distal cheek teeth in horses of different ages, quantify age-related cheek teeth mesial and distal dental drift, and measure the cheek t...
Evaluation of the treatment of equine glandular gastric disease with either long-acting-injectable or oral omeprazole.
Veterinary medicine and science    February 15, 2022   Volume 8, Issue 2 561-567 doi: 10.1002/vms3.728
Gough S, Hallowell G, Rendle D.Equine glandular gastric disease (EGGD) is common in domesticated horses and can be challenging to treat. Oral omeprazole (ORLO) is used widely but the clinical response is frequently poor. Objective: To compare rates of EGGD healing and improvement between ORLO and a long-acting injectable omeprazole preparation (LAIO). Methods: Retrospective clinical study. Methods: The case records and gastroscopy images of horses presenting to masked for peer review over a 12-month period were reviewed, with images blindly assessed by one of the authors. Treatment responses to 4 mg/kg LAIO administered eve...
Ureteral Endoscopy to Detect Upper Urinary Tract Diseases in Horses.
Journal of equine veterinary science    February 14, 2022   Volume 112 103899 doi: 10.1016/j.jevs.2022.103899
Busechian S, Marchesi MC, Vuerich M, Corsalini J, Nannarone S, Arcelli R, Ortolani F, Rueca F, Gialletti R.Ureteral endoscopy is a routine procedure in human medicine, whereas the reports of this procedure on horses are few and far between. The aim of this paper is to describe the endoscopic technique to evaluate the ureters in standing, sedated horses. An endoscopy of the ureters and lower urinary tract was performed using flexible endoscopes on 4 horses, 3 mares and one gelding. The animals were sedated with alpha-2-agonists and an epidural anaesthesia was given. An endoscopy of the ureter in the horse is easy to perform, causes the animal no adverse effects and could provide significant informat...
Treatment of primary hyperparathyroidism in a Miniature Horse using chemical ablation of abnormal parathyroid tissue localized by 3-phase computed tomography.
Journal of veterinary internal medicine    February 12, 2022   Volume 36, Issue 2 798-804 doi: 10.1111/jvim.16390
Colmer SF, Wulster K, Johnson AL, Levine DG, Underwood C, Watkins TW, Van Eps AW.A 15-year-old Miniature Horse mare with persistently increased plasma calcium (total and ionized) and serum parathyroid hormone concentrations was presented for suspected primary hyperparathyroidism. Ultrasonography of the thyroid region identified an enlarged heterogeneous mass axial to the right thyroid lobe suggestive of an enlarged parathyroid gland, which was further confirmed using sestamibi nuclear scintigraphy and 3-phase computed tomography. Percutaneous ultrasound-guided ethanol ablation of the mass, a method not previously described in the horse, was performed under general anesthes...
The Indicators of Clinical and Subclinical Mastitis in Equine Milk.
Animals : an open access journal from MDPI    February 11, 2022   Volume 12, Issue 4 doi: 10.3390/ani12040440
Domańska D, Trela M, Pawliński B, Podeszewski B, Domino M.The somatic cell count in milk (SCC) and electrical conductivity of milk (ECM) are indicators of the health status of the mammary gland. Among somatic cells, mainly polymorphonuclear neutrophils (PMN), macrophages (MAC), and lymphocytes (LYM) are rated. This study aimed to determine the SCC, PMN, MAC, LYM, ECM, and bacteriological index (BII) in milk collected from mares with (CM) and without (NCM) clinical symptoms of mastitis concerning mares with (SM) and without (NSM) subclinical mastitis. Milk samples were collected from 27 mares divided into NCM (n = 12) and CM (n = 15) groups. In sample...
Pathology in Practice.
Journal of the American Veterinary Medical Association    February 2, 2022   Volume 260, Issue 8 1-3 doi: 10.2460/javma.20.09.0497
de Cecco BS, Sasaki E, Nevarez JG, Cummings CO, Langohr IM, Piero FD.No abstract available
First reported case of fragile foal syndrome type 1 in the Thoroughbred caused by PLOD1 c.2032G>A.
Equine veterinary journal    February 1, 2022   Volume 54, Issue 6 1086-1093 doi: 10.1111/evj.13547
Grillos AS, Roach JM, de Mestre AM, Foote AK, Kinglsey NB, Mienaltowski MJ, Bellone RR.Warmblood Fragile Foal Syndrome Type 1 (WFFS) is an autosomal recessive disorder reported previously only in warmbloods and thought to be caused by a variant in the gene procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1, c.2032G>A, p.Gly678Arg). Given the presentation of this Thoroughbred case, we hypothesised that a similar genetic mechanism caused this phenotype. Objective: To describe the pathological and genetic findings on a foal presenting to a veterinary practice in the UK with skin lesions similar to other Ehlers-Danlos Syndromes, including those documented for warmbloods with W...
Effect of 15° Reverse Trendelenburg Position on Arterial Oxygen Tension during Isoflurane Anesthesia in Horses.
Animals : an open access journal from MDPI    February 1, 2022   Volume 12, Issue 3 353 doi: 10.3390/ani12030353
Tucker L, Almeida D, Wendt-Hornickle E, Baldo CF, Allweiler S, Guedes AGP.Lower than expected arterial oxygen tension (PaO) continues to be an unresolved problem in equine anesthesia. The aim of this randomized, crossover, and prospective study using six adult horses is to determine if a 15° reverse Trendelenburg position (RTP) increases PaO during inhalation anesthesia. Under constant-dose isoflurane anesthesia, dorsally recumbent horses were positioned either horizontally (HP) or in a 15° RTP for 2 h. Lungs were mechanically ventilated (15 mL/kg, 6 breaths/min). Arterial carbon dioxide tension (PaCO), PaO, inspired oxygen fraction (FiO), and end-tidal carbon dio...
Bias Associated with Peripheral Non-Invasive Compared to Invasive Arterial Blood Pressure Monitoring in Healthy Anaesthetised and Standing Horses Using the Bionet BM7Vet.
Veterinary sciences    January 28, 2022   Volume 9, Issue 2 52 doi: 10.3390/vetsci9020052
Pratt S, Barnes TS, Cowling N, de Klerk K, Rainger J, Sole-Guitart A, Woldeyohannes S, Goodwin W.To compare arterial blood pressure (ABP) measured invasively (IBP) to ABP measured non-invasively (NIBP) via oscillometry in healthy anaesthetised and standing horses using the Bionet BM7Vet. Fourteen horses were anaesthetised for elective procedures (anaesthetised group) and 10 horses were enrolled for standing blood pressure manipulation (standing group). In both groups, IBP and NIBP-corrected to heart level were measured every 3 min using the Bionet BM7Vet. The overall mean difference (bias), standard deviation and limits of agreement (LOA) were calculated for paired IBP and NIBP systolic (...
A Unique Injury Secondary to a Horse Bite.
Clinical pediatrics    January 28, 2022   Volume 61, Issue 3 299-301 doi: 10.1177/00099228221074774
Campton A, Brewer L, Dahl A, Fraser JD, Kangas J.No abstract available
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