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Topic:Computer-Assisted Analysis
Computer-assisted analysis in equine research involves the use of computational tools and software to process and evaluate data related to horses. This approach enhances the ability to analyze complex datasets, ranging from genetic information to biomechanical assessments. Applications include gait analysis, where motion capture technology and algorithms assess locomotion patterns, and genomic studies, where bioinformatics tools interpret genetic sequences. Additionally, computer-assisted methods are employed in imaging techniques, such as MRI and CT scans, to improve diagnostic accuracy. This page compiles peer-reviewed research studies and scholarly articles that explore the methodologies, applications, and advancements in computer-assisted analysis within the field of equine science.
[Animal bites at the casualty department of the Oslo City Council]. During a 2-year period all Casualty Department data charts with the diagnosis "animal bite" were reviewed as part of internal quality control. Of 1,051 recorded episodes, 503 (48%) were women and 147 (14%) children under 16 years of age. 951 (90%) wounds were treated without closure. Half of the patients were not given antibiotics on the first visit, whereas one third were given penicillin. Tetanus status had been evaluated on 1,015 (97%) charts. Most bites were caused by dogs (76%), cats (17%), and horses (2%). Children were the victims of 118 (15%) dog bites, eight (4%) cat bites, and ten (5...
Welfare of competition horses. In the large majority of cases and circumstances, horses benefit from their association with man. However, abuse of horses can occur, due to neglect or through the pressures of competition. The welfare of all animals, including competition horses, has become increasingly topical over the past ten years. Equestrian sport is coming under closer public scrutiny due to reports of apparent abuse. The bodies responsible for regulating these sports strenuously endeavour to protect the welfare of horses which compete under their rules and regulations. The Fédération Equestre Internationale (FEI: Int...
Ultrasonographically detected changes in equine superficial digital flexor tendons during the first months of race training. The forelimb superficial digital flexor (SDF) tendons of 6 Thoroughbreds were examined clinically and ultrasonographically during the first 4 months of race training. Sonograms were interpreted clinically and by use of computer-aided analysis. Tendon tissue from all horses was examined histologically at the end of the study. Computer-aided analysis of sonograms of the SDF tendons revealed trends toward an increase in mean cross-sectional area and a decrease in mean echogenicity over time with training. An inverse relation was found between increase in cross-sectional area and decrease in mean ...
Computer-assisted three-dimensional gait analysis of amphotericin-induced carpal lameness in horses. Motion of 6 clinically sound horses trotting at a speed of 4 m/s on a treadmill was captured by video cameras before and 9, 16, and 23 days after amphotericin-induced lameness to determine the quantitative variables of three-dimensional computer-assisted image analysis that objectively describe carpal lameness. Amphotericin-B was used to induce lameness, and phenylbutazone (2.2 mg/kg of body weight, PO, once) and butorphanol tartrate (0.1 mg/kg IM, q 6 h, to effect) were used to control discomfort. Four 60-Hz cameras were symmetrically placed around the treadmill to capture 6 seconds of images...
Pharmacokinetics, penetration into cerebrospinal fluid, and hematologic effects after multiple oral administrations of pyrimethamine to horses. Pharmacokinetics, CSF penetration, and hematologic effects of oral administration of pyrimethamine were studied after multiple dosing. Pyrimethamine (1 mg/kg of body weight) was administered orally once a day for 10 days to 5 adult horses, and blood samples were collected frequently after the first, fifth, and tenth doses. The CSF samples were obtained by cisternal puncture 4 to 6 hours after administration of the first, third, seventh, and tenth doses. Pyrimethamine concentration in plasma and CSF was quantified by gas chromatography, and plasma concentration-time data were analyzed, using a ...
Computer-based collection and analysis of myoelectric activity of the intestine in horses. Extracellular myoelectric activity from the terminal ileum, cecum, and colonic pelvic flexure was assessed in 4 adult horses. The collection and analysis of myoelectric data involved the development and use of a computer-based system. After collection, the myoelectric signal was digitally filtered to enhance the activity of interest. The smoothed signal was then processed by use of computer programs designed to identify and count spike-burst activity and estimate burst duration. The intense phases of myoelectric complexes also were identified. The propagation of myoelectric spike-burst activit...
Technique for continuous stride analysis of horses exercising on a treadmill. A technique for continuous computerised recording and analysis of the stride of horses on a treadmill is described. Advantages of the system are low cost, the use of normal shoes and the calculation of stride parameters in real time.
The reliability of endoscopic examination in assessment of arytenoid cartilage movement in horses. Part I: Subjective and objective laryngeal evaluation. Videorecordings of the laryngeal activity of 108 unsedated horses were obtained at rest by passing a flexible videoendoscope into the nasopharynx through the right ventral meatus. All videotaped images were reviewed once, and 72 were reviewed twice, by three veterinarians. Laryngeal cartilage movement was assessed subjectively with a five-tier grading system. The mean intraobserver agreement was 83.3% (range, 75.0%-90.2%) with a kappa statistic of .65 to .98. The mean interobserver agreement was 79.0% (range, 70.4%-80.6%) with a kappa statistic of .51 to .90. A computer program was developed t...
Immunoturbidimetric quantification of serum immunoglobulin G concentration in foals. Immunoturbidimetric determination of serum IgG concentration in foals was compared with the reference methods of single radial immunodiffusion and serum protein electrophoresis. High positive correlations were discovered when the technique was compared with either of these reference methods. The zinc sulfate turbidity test for serum IgG estimation was also evaluated. Although a positive correlation was discovered when the latter method was compared with reference methods, it was not as strong as the correlation between reference methods and the immunoturbidimetric method. The immunoturbidimetr...
Chromogenic assay for equine plasminogen. A functional assay for equine plasminogen was established, using urokinase as the activator, a synthetic chromogenic substrate, a computer-assisted centrifugal analyzer, and acidified/neutralized plasma. One documented effect of plasma acidification appears to be inactivation of alpha-2-antiplasmin. Intra- and interassay precision testing yielded coefficients of variation of 4.1% (n = 10) and 5.6% (n = 26), respectively. Plasminogen was stable in equine plasma stored up to 1 week at 4 C and up to 5 months at -70 C. Plasminogen in nonacidified equine plasma was not activated by urokinase, strep...
Digital processing of equine exercise electrocardiograms. We have developed and used a system for recording and analyzing the electrocardiogram (ECG) of the horse during exercise. The system consists of a commercial ECG transmitter telemetering a Z lead (base-apex) ECG from an exercising horse. The received data are then remodulated at an audio frequency and stored on a audio cassette recorder. Exercise protocols of up to 10 minutes are digitized using a Macintosh II computer. For rhythm analysis, a computer program to identify the various waves of the ECG uses a modification and refinement of the integrated-squared-derivative (ISD) technique. This t...
Microprocessor-based system for collection and storage of the equine vectorcardiogram. To evaluate the clinical application of a semiorthogonal lead system for use in the horse, an inexpensive means of recording and storing the ECG was required which would allow the subsequent vectorcardiographic analysis to be computerized. In investigating the various options for the system the basic requirements for the digitization of analogue data were reviewed and previous studies examined. The system subsequently developed used an 8080 microprocessor and a multichannel 8-bit analogue to digital converter. This unit was signal-level compatible with the laboratory recorder used in the study...
The resolution of mixtures of viable mammalian cells into homogeneous fractions by zonal centrifugation. Large-scale separation of mixtures of mammalian cells was obtained with the A-1X zonal centrifuge rotor and density gradients consisting of Ficoll dissolved in modified Eagle's MEM suspension-culture medium. The cells remained viable as tested by plating efficiency or by motility observed with time-lapse photography. Rabbit thymocyte and HeLa cell mixtures were separated with 99 and 89 per cent purity, respectively. Mixtures of thymocytes and suspension-cultured, human acute leukemia cells (Roswell Park strain LKID) were separated with 93 and 91% purity, respectively. HeLa cells were isolated ...
