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Topic:Disease control

Disease control in horses encompasses the strategies and measures implemented to prevent, manage, and eradicate infectious and non-infectious diseases within equine populations. This field involves the study of pathogen transmission, host-pathogen interactions, and the development of effective vaccination and biosecurity protocols. Disease control also includes monitoring and surveillance of equine health to identify outbreaks and implement timely interventions. Key aspects of disease control in horses involve understanding the epidemiology of equine diseases, improving diagnostic techniques, and enhancing treatment options. This page compiles peer-reviewed research studies and scholarly articles that explore various methodologies, technologies, and practices aimed at controlling diseases in horses, with a focus on improving overall equine health and welfare.
Evidence in Practice – A Pilot Study Leveraging Companion Animal and Equine Health Data from Primary Care Veterinary Clinics in New Zealand.
Frontiers in veterinary science    December 23, 2016   Volume 3 116 doi: 10.3389/fvets.2016.00116
Muellner P, Muellner U, Gates MC, Pearce T, Ahlstrom C, O'Neill D, Brodbelt D, Cave NJ.Veterinary practitioners have extensive knowledge of animal health from their day-to-day observations of clinical patients. There have been several recent initiatives to capture these data from electronic medical records for use in national surveillance systems and clinical research. In response, an approach to surveillance has been evolving that leverages existing computerized veterinary practice management systems to capture animal health data recorded by veterinarians. Work in the United Kingdom within the VetCompass program utilizes routinely recorded clinical data with the addition of fur...
Genotyping of friesian horses to detect a hydrocephalus-associated c.1423C>T mutation in B3GALNT2 using PCR-RFLP and PCR-PIRA methods: Frequency in stallion horses in México.
Molecular and cellular probes    December 21, 2016   Volume 32 69-71 doi: 10.1016/j.mcp.2016.12.005
Ayala-Valdovinos MA, Galindo-García J, Sánchez-Chiprés D, Duifhuis-Rivera T.Hydrocephalus in Friesian horses is an autosomal recessive hereditary disease that can result in an abortion, a stillbirth, or euthanization of a newborn foal. Here, the hydrocephalus-associated c.1423C > T mutation in B3GALNT2 gene was detected with PCR-RFLP and PCR-PIRA methods for horse genotyping. A preliminary genotyping survey was performed on 83 randomly selected Friesian stallion horses to determine the current allele frequency in Mexico. The frequency of the mutant T allele was 9.6%.
Science-in-brief: Clinical highlights from BEVA Congress 2016.
Equine veterinary journal    December 17, 2016   Volume 49, Issue 1 10-12 doi: 10.1111/evj.12644
Chauché C, Kennedy R.No abstract available
Locally Acquired Eastern Equine Encephalitis Virus Disease, Arkansas, USA.
Emerging infectious diseases    December 15, 2016   Volume 22, Issue 12 2216-2217 doi: 10.3201/eid2212.160844
Garlick J, Lee TJ, Shepherd P, Linam WM, Pastula DM, Weinstein S, Schexnayder SM.No abstract available
The Optimisation of Pseudotyped Viruses for the Characterisation of Immune Responses to Equine Influenza Virus.
Pathogens (Basel, Switzerland)    December 15, 2016   Volume 5, Issue 4 68 doi: 10.3390/pathogens5040068
Scott SD, Kinsley R, Temperton N, Daly JM.Pseudotyped viruses (PVs) produced by co-transfecting cells with plasmids expressing lentiviral core proteins and viral envelope proteins are potentially powerful tools for studying various aspects of equine influenza virus (EIV) biology. The aim of this study was to optimise production of equine influenza PVs. Co-transfection of the HAT protease to activate the haemagglutinin (HA) yielded a higher titre PV than TMPRSS2 with the HA from A/equine/Richmond/1/2007 (H3N8), whereas for A/equine/Newmarket/79 (H3N8), both proteases resulted in equivalent titres. TMPRSS4 was ineffective with the HA of...
Early detection of West Nile virus in France: quantitative assessment of syndromic surveillance system using nervous signs in horses.
Epidemiology and infection    December 12, 2016   Volume 145, Issue 5 1044-1057 doi: 10.1017/S0950268816002946
Faverjon C, Vial F, Andersson MG, Lecollinet S, Leblond A.West Nile virus (WNV) is a growing public health concern in Europe and there is a need to develop more efficient early detection systems. Nervous signs in horses are considered to be an early indicator of WNV and, using them in a syndromic surveillance system, might be relevant. In our study, we assessed whether or not data collected by the passive French surveillance system for the surveillance of equine diseases can be used routinely for the detection of WNV. We tested several pre-processing methods and detection algorithms based on regression. We evaluated system performances using simulate...
A recombinant fusion protein consisting of West Nile virus envelope domain III fused in-frame with equine CD40 ligand induces antiviral immune responses in horses.
Veterinary microbiology    December 8, 2016   Volume 198 51-58 doi: 10.1016/j.vetmic.2016.12.008
Liu SA, Haque M, Stanfield B, Andrews FM, Roy AA, Kousoulas KG.West Nile Virus (WNV) is endemic in the US and causes severe neurologic disease in horses since its introduction in 1999. There is no effective pharmaceutical treatment for WNV infection rendering vaccination as the only approach to prevention and control of disease. The purpose of this study was to evaluate a recombinant vaccine containing domain III (DIII) of the WNV envelope glycoprotein with and without a natural adjuvant equine (CD40L) in producing virus neutralizing antibodies in horses. Serum IgG1 concentration in the groups of horses vaccinated with the DIII-CD40L+TiterMax and DIII-CD4...
Parasites Determined by Fecal Examination in Horses in Erzurum.
Turkiye parazitolojii dergisi    December 3, 2016   Volume 40, Issue 3 147-151 doi: 10.5152/tpd.2016.4792
Avcıoğlu H, Güven E, Balkaya İ, Yavuz Ş, Abay U, Akyüz M, Eltas Ö.This study aimed to determine the parasites present in horses belonging to the Erzurum Province. Methods: Fecal samples were collected from 76 horses of different ages, genders and breeds in Erzurum. Individual fecal samples were collected and examined by flotation and sedimentation methods. Results: The following species were detected: strongylid egg (57.89%), Parascaris equorum (10.52%), Dicrocoelium dendriticum (2.63%), Fasciola spp. (2.63%) eggs, and Eimeria spp. oocysts (5.26%). Conclusions: Equine animals are significantly infected with Strongylosis in the Erzurum Province, and effective...
A systematic review of leptospirosis on dogs, pigs, and horses in Latin America.
Tropical animal health and production    December 1, 2016   Volume 49, Issue 2 231-238 doi: 10.1007/s11250-016-1201-8
Pinto PS, Libonati H, Lilenbaum W.Leptospirosis is a worldwide zoonosis which can affect many species. Control programs need accurate diagnosis to be successful, and currently, diagnosis relies on serology. It presents three main issues: the sampling, the antigen panel, and the cutoff point. Herein, we propose a systematic review on leptospirosis among dogs, pigs, and horses in Latin America in order to improve the understanding of the seroepidemiology of leptospirosis in these species in the region as well as the temporal development of the research on this topic and, consequently, improve the chances of success on control pr...
How to Meet the Last OIE Expert Surveillance Panel Recommendations on Equine Influenza (EI) Vaccine Composition: A Review of the Process Required for the Recombinant Canarypox-Based EI Vaccine.
Pathogens (Basel, Switzerland)    November 25, 2016   Volume 5, Issue 4 64 doi: 10.3390/pathogens5040064
Paillot R, Rash NL, Garrett D, Prowse-Davis L, Montesso F, Cullinane A, Lemaitre L, Thibault JC, Wittreck S, Dancer A.Vaccination is highly effective to prevent, control, and limit the impact of equine influenza (EI), a major respiratory disease of horses. However, EI vaccines should contain relevant equine influenza virus (EIV) strains for optimal protection. The OIE expert surveillance panel annually reviews EIV evolution and, since 2010, the use of Florida clade 1 and 2 sub-lineages representative vaccine strains is recommended. This report summarises the development process of a fully- updated recombinant canarypox-based EI vaccine in order to meet the last OIE recommendations, including the vaccine mode ...
Seroprevalence and spatial distribution of Toxoplasma gondii infection in cats, dogs, pigs and equines of the Fernando de Noronha Island, Brazil.
Parasitology international    November 25, 2016   Volume 66, Issue 2 43-46 doi: 10.1016/j.parint.2016.11.014
Magalhães FJR, Ribeiro-Andrade M, Souza FM, Lima Filho CDF, Biondo AW, Vidotto O, Navarro IT, Mota RA.Little is known about toxoplasmosis in animals of the Fernando de Noronha Island, Brazil. Therefore, we investigated the prevalence of Toxoplasma gondii infection in the total population of pet cats (n=348), dogs (n=320), pigs (n=27), equines (n=101), as well as a significant portion of the population of feral cats (n=247) of the Island by Indirect Fluorescent Antibody Test. Anti-T. gondii IgG antibodies were found in 71.26%, 54.74%, 48.75%, 51.85% and 22.7%, of the pet and feral cats, dogs, pigs and equines, respectively, demonstrating a high prevalence of T. gondii infection in the wild and ...
Disease and pharmacologic risk factors for first and subsequent episodes of equine laminitis: A cohort study of free-text electronic medical records.
Preventive veterinary medicine    November 22, 2016   Volume 136 11-18 doi: 10.1016/j.prevetmed.2016.11.012
Welsh CE, Duz M, Parkin TDH, Marshall JF.Electronic medical records from first opinion equine veterinary practice may represent a unique resource for epidemiologic research. The appropriateness of this resource for risk factor analyses was explored as part of an investigation into clinical and pharmacologic risk factors for laminitis. Amalgamated medical records from seven UK practices were subjected to text mining to identify laminitis episodes, systemic or intra-synovial corticosteroid prescription, diseases known to affect laminitis risk and clinical signs or syndromes likely to lead to corticosteroid use. Cox proportional hazard ...
Antimicrobial stewardship in the treatment of equine bacterial infections.
Veterinary journal (London, England : 1997)    November 21, 2016   Volume 219 4-5 doi: 10.1016/j.tvjl.2016.11.009
Johns I.No abstract available
Validation of a method for sedatives and β-blockers determination in swine, bovine and equine kidney using liquid chromatography coupled with tandem mass spectrometry.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment    November 21, 2016   Volume 34, Issue 1 32-39 doi: 10.1080/19440049.2016.1252468
de Oliveira LG, Barreto F, Hoff R, Rübensam G, Scherer Kurz MH, Galle G, Gonçalves FF.A method for the determination of five sedatives and 14 β-blocker residues in swine, bovine and equine kidney was validated. Samples were extracted with acetonitrile and purified using dispersive solid phase extraction (d-SPE) with Celite 545 with subsequent analysis by LC-MS/MS. A simplified protocol was applied to validate the method scope extension to include new matrices. Parameters such as recovery, trueness, linearity (r), relative standard deviation (RSD), decision limit (CCα) and method capability (CCβ) were measured for the bovine and equine kidney matrices. The method was applied ...
Life cycle of Spinose ear tick, Otobius megnini (Acari: Argasidae) infesting the race horses in Nuwara Eliya, Sri Lanka.
Acta tropica    November 18, 2016   Volume 166 164-176 doi: 10.1016/j.actatropica.2016.11.026
Diyes GCP, Rajakaruna RS.Otobius megnini infests mainly domesticated and wild animals and occasionally humans. It has been identified as an agent of human and horse otoacariasis in Sri Lanka. The number of nymphal stages in the life cycle of O. megnini varies from one to three in different geographic regions. The present study determined the life cycle of O. megnini infesting the racehorses in Nuwara Eliya. A tick colony was initiated from fully engorged nymphs collected from horses and maintained at 10°C, 22°C and 28°C. Immature stages were reared on New Zealand rabbits. Only the larvae weighing more than 0.9mg (8...
[Vigilance for veterinary medicinal products: Reports of adverse reactions in the year 2015].
Schweizer Archiv fur Tierheilkunde    November 9, 2016   Volume 158, Issue 11 743-747 doi: 10.17236/sat00090
Müntener C, Kupper J, Naegeli H, Gassner B.A total of 292 adverse reactions to veterinary medicinal products were reported during the year 2015. This represents an increase of 9% compared to the previous year (268 reports). Similar to previous years, most of the reactions reported were linked to the use of antiparasitics (55.1%), non-steroidal anti-inflammatory products (8.9%) or antiinfectives (9.3%). The affected animal species were primarily dogs (198 reports) and cats (42 reports), followed by cattle (31 reports) and horses (8 reports). Additional 42 reports were provided within the frame of consultations with Tox Info Suisse in ZÃ...
Dynamics of Parascaris and Strongylus spp. parasites in untreated juvenile horses.
Veterinary parasitology    November 7, 2016   Volume 230 62-66 doi: 10.1016/j.vetpar.2016.11.002
Fabiani JV, Lyons ET, Nielsen MK.Parasite control in foals is of utmost importance due to the high susceptibility to parasitic infection and disease in this age group. Foals are commonly co-infected with strongyle and ascarid parasites, which complicate parasite control strategies. The present study retrospectively investigated necropsy records of foals born into a university herd kept without anthelmintic treatment since 1979. The aims were to statistically analyze the relationship between fecal egg counts, worm burdens, foal age, sex, and season with specific focus on Parascaris and Strongylus spp. A total of 83 foals born ...
Comparison of assays for the detection of West Nile virus antibodies in equine serum after natural infection or vaccination.
Veterinary immunology and immunopathology    November 3, 2016   Volume 183 1-6 doi: 10.1016/j.vetimm.2016.10.015
Joó K, Bakonyi T, Szenci O, Sárdi S, Ferenczi E, Barna M, Malik P, Hubalek Z, Fehér O, Kutasi O.West Nile virus (WNV) mainly infects birds, horses and humans. Outcomes of the infection range from mild uncharacteristic signs to fatal neurologic disease. The main objectives of the present study were to measure serum IgG and IgM antibodies in naturally exposed and vaccinated horses and to compare results of haemagglutination inhibition test (HIT), enzyme-linked immunosorbent assay (ELISA) and plaque reduction neutralisation test (PRNT). Altogether 224 animals were tested by HIT for WNV antibodies and 41 horses were simultaneously examined by ELISA and PRNT. After primary screening for WNV a...
Equine disease surveillance: quarterly summary.
The Veterinary record    October 30, 2016   Volume 179, Issue 17 428-431 doi: 10.1136/vr.i5679
of surveillance testing, April to June 2016Continuing reports of abortion due to equine herpesvirus type 1 infectionInternational disease occurrence in the second quarter of 2016These are among matters discussed in the most recent quarterly equine disease surveillance report, prepared by Defra, the Animal Health Trust and the British Equine Veterinary Association.
West Nile virus ‘circulation’ in Vojvodina, Serbia: Mosquito, bird, horse and human surveillance.
Molecular and cellular probes    October 21, 2016   Volume 31 28-36 doi: 10.1016/j.mcp.2016.10.011
Efforts to detect West Nile virus (WNV) in the Vojvodina province, northern Serbia, commenced with human and mosquito surveillance in 2005, followed by horse (2009) and wild bird (2012) surveillance. The knowledge obtained regarding WNV circulation, combined with the need for timely detection of virus activity and risk assessment resulted in the implementation of a national surveillance programme integrating mosquito, horse and bird surveillance in 2014. From 2013, the system showed highly satisfactory results in terms of area specificity (the capacity to indicate the spatial distribution of t...
Leukoencephalomalacia Outbreak in Horses due to Consumption of Contaminated Hay.
Journal of veterinary internal medicine    October 15, 2016   Volume 30, Issue 6 1879-1881 doi: 10.1111/jvim.14588
Vendruscolo CP, Frias NC, de Carvalho CB, de Sá LR, Belli CB, Baccarin RY.No abstract available
The economic impact of Bluetongue and other orbiviruses in sub-Saharan Africa, with special reference to Southern Africa.
Veterinaria italiana    October 11, 2016   Volume 52, Issue 3-4 375-381 doi: 10.12834/VetIt.503.2427.3
Grewar JD.Bluetongue (BT) and African horse sickness (AHS) are considered the most important orbiviral diseases in Southern Africans countries. The general endemic status makes these diseases challenging to be quanti ed in terms of their economic impact. Using country reported data from BT and AHS outbreaks and cases, as well as international trade data, the economic impact of BT and AHS is evaluated on local, regional, and global scales. Local scale impact in the Southern African region is underestimated as shown by the underreporting of BT and AHS. Exceptions occur during epidemic cycles of the diseas...
Advances in Stallion Semen Cryopreservation.
The Veterinary clinics of North America. Equine practice    October 8, 2016   Volume 32, Issue 3 521-530 doi: 10.1016/j.cveq.2016.08.003
Alvarenga MA, Papa FO, Ramires Neto C.The use of stallion frozen semen minimizes the spread of disease, eliminates geographic barriers, and preserves the genetic material of the animal for an unlimited time. Significant progress on the frozen thawed stallion semen process and consequently fertility has been achieved over the last decade. These improvements not only increased fertility rates but also allowed cryopreservation of semen from "poor freezers." This article reviews traditional steps and new strategies for stallion semen handling and processing that are performed to overcome the deleterious effects of semen preservation a...
Is Corynebacterium pseudotuberculosis infection (pigeon fever) in horses an emerging disease in western Canada?
The Canadian veterinary journal = La revue veterinaire canadienne    October 7, 2016   Volume 57, Issue 10 1062-1066 
Corbeil LE, Morrissey JF, Léguillette R.This report describes 5 horses in the southern Alberta region with typical and atypical external abscessation due to Corynebacterium pseudotuberculosis (pigeon fever). "Pigeon fever" has recently been diagnosed in new geographic regions in North America and should be kept as a differential diagnosis by practitioners when an external or internal abscess is identified in a horse. L’infection parCorynebacterium pseudotuberculosis(fièvre du pigeon) chez les chevaux est-elle une maladie émergente dans l’Ouest canadien? Ce rapport décrit cinq chevaux dans la région sud de l’Alberta atteint...
Brazilian borreliosis with special emphasis on humans and horses.
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]    October 4, 2016   Volume 48, Issue 1 167-172 doi: 10.1016/j.bjm.2016.09.005
Basile RC, Yoshinari NH, Mantovani E, Bonoldi VN, Macoris DD, Queiroz-Neto A.Borreliosis caused by Borrelia burgdorferi sensu lato is a cosmopolitan zoonosis studied worldwide; it is called Lyme disease in many countries of the Northern Hemisphere and Lyme-like or Baggio-Yoshinari Syndrome in Brazil. However, despite the increasing number of suspect cases, this disease is still neglected in Brazil by the medical and veterinary communities. Brazilian Lyme-like borreliosis likely involves capybaras as reservoirs and Amblyomma and Rhipicephalus ticks as vectors. Thus, domestic animals can serve as key carriers in pathogen dissemination. This zoonosis has been little studi...
Serological evidence of equine influenza virus in horse stables in Kaduna, Nigeria.
Journal of equine science    September 30, 2016   Volume 27, Issue 3 99-105 doi: 10.1294/jes.27.99
Meseko CA, Ehizibolo DO, Nwokike EC, Wungak YS.Equine influenza virus (EIV) is a major cause of acute respiratory diseases in horses in most parts of the world that results in severe economic losses. Information on the epidemiology of EIV in tropical Africa is scanty. An enzyme-linked immunosorbent assay (ELISA) was used to detect the presence of influenza A virus nucleoprotein (NP) in 284 horse sera in Kaduna State, Northern Nigeria. The ELISA-positive sera were further examined for hemagglutination inhibition (HI) antibodies to two strains each of H3N8 and H7N3 subtypes of influenza A virus. The results showed that antibodies against inf...
West Nile virus transmission: results from the integrated surveillance system in Italy, 2008 to 2015.
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin    September 30, 2016   Volume 21, Issue 37 30340 doi: 10.2807/1560-7917.ES.2016.21.37.30340
Rizzo C, Napoli C, Venturi G, Pupella S, Lombardini L, Calistri P, Monaco F, Cagarelli R, Angelini P, Bellini R, Tamba M, Piatti A, Russo F, Palù G....In Italy a national Plan for the surveillance of imported and autochthonous human vector-borne diseases (chikungunya, dengue, Zika virus disease and West Nile virus (WNV) disease) that integrates human and veterinary (animals and vectors) surveillance, is issued and revised annually according with the observed epidemiological changes. Here we describe results of the WNV integrated veterinary and human surveillance systems in Italy from 2008 to 2015. A real time data exchange protocol is in place between the surveillance systems to rapidly identify occurrence of human and animal cases and to de...
Radiation safety in equine practice.
The Veterinary record    September 24, 2016   Volume 179, Issue 12 312 doi: 10.1136/vr.i5108
Kinns J.No abstract available
Working across Europe to improve donkey welfare.
The Veterinary record    September 24, 2016   Volume 179, Issue 12 298-300 doi: 10.1136/vr.i4112
Thiemann A, Foxcroft A.The UK public and veterinary profession often think of the equine charity sector as dealing with issues directly related to the UK equine population - overproduction, rehoming, shelter and welfare. However, the Donkey Sanctuary, like many UK-based equine charities, also works in Europe and further afield to try to address a much broader range of issues, as Alex Thiemann and Andy Foxcroft explain.
Comparative Risk Analysis of Two Culicoides-Borne Diseases in Horses: Equine Encephalosis More Likely to Enter France than African Horse Sickness.
Transboundary and emerging diseases    September 23, 2016   Volume 64, Issue 6 1825-1836 doi: 10.1111/tbed.12577
Faverjon C, Leblond A, Lecollinet S, Bødker R, de Koeijer AA, Fischer EAJ.African horse sickness (AHS) and equine encephalosis (EE) are Culicoides-borne viral diseases that could have the potential to spread across Europe if introduced, thus being potential threats for the European equine industry. Both share similar epidemiology, transmission patterns and geographical distribution. Using stochastic spatiotemporal models of virus entry, we assessed and compared the probabilities of both viruses entering France via two pathways: importation of live-infected animals or importation of infected vectors. Analyses were performed for three consecutive years (2010-2012). Se...
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