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Topic:Disease Management

Disease management in horses encompasses the strategies and practices employed to prevent, control, and treat diseases affecting equine populations. This field involves understanding the etiology, transmission, and clinical presentation of various equine diseases, as well as implementing biosecurity measures and therapeutic interventions. Common diseases in horses include equine influenza, strangles, and equine herpesvirus. Effective disease management relies on accurate diagnosis, vaccination protocols, and the use of antimicrobials and other treatments. This page compiles peer-reviewed research studies and scholarly articles that explore the methodologies, challenges, and advancements in managing diseases in equine health.
Overview of the Current Situation in a Sample of Headshakers and Owner Assessment of Effective Therapeutic Measures Used in Germany.
Journal of equine veterinary science    September 17, 2020   Volume 95 103270 doi: 10.1016/j.jevs.2020.103270
Stange LM, Krieter J, Czycholl I.Equine headshaking syndrome is a problematic behavior that has been described in literature for more than 100 years. The signs of headshaking syndrome appear frequently and violently so that riding the horse can be dangerous. The aim of this research was to gain an overview of the underlying causes of equine headshaking syndrome to identify effective treatment options, reduce the distress of horses and, in a second step, potentially improve therapeutic possibilities for horse owners and veterinarians. Most studies on prevalence originate from Anglo-American countries, so this research was to ...
Climate change is likely to increase the development rate of anthelmintic resistance in equine cyathostomins in New Zealand.
International journal for parasitology. Drugs and drug resistance    September 17, 2020   Volume 14 73-79 doi: 10.1016/j.ijpddr.2020.09.001
Sauermann CW, Leathwick DM, Lieffering M, Nielsen MK.Climate change is likely to influence livestock production by increasing the prevalence of diseases, including parasites. The traditional practice of controlling nematodes in livestock by the application of anthelmintics is, however, increasingly compromised by the development of resistance to these drugs in parasite populations. This study used a previously developed simulation model of the entire equine cyathostomin lifecycle to investigate the effect a changing climate would have on the development of anthelmintic resistance. Climate data from six General Circulation Models based on four di...
Use of saline contrast ultrasonography in the diagnosis of complete jugular vein occlusion in a horse.
Open veterinary journal    September 15, 2020   Volume 10, Issue 3 308-316 doi: 10.4314/ovj.v10i3.9
Corda A, Columbano N, Secchi V, Scanu A, Parpaglia MLP, Careddu GM, Passino ES.Thrombophlebitis and thrombosis are the most common causes of jugular vein occlusion in horses. Medical and surgical treatments aim to recanalize the occluded vessel and reduce proximal venous congestion and edema. The present report describes a clinical case of equine jugular vein thrombosis (JVT) with complete vein occlusion diagnosed by saline contrast ultrasonography (SCU) and confirmed by contrast venography. Our results demonstrated that the SCU test can be easily performed and objectively interpreted using standard ultrasound equipment; it is not expensive and it does not require x-ray...
Seroprevalence and risk factors associated with Equine piroplasmosis in North Egypt.
Comparative immunology, microbiology and infectious diseases    September 13, 2020   Volume 73 101549 doi: 10.1016/j.cimid.2020.101549
Selim A, Khater H.Equine piroplasmosis (EP) is caused by Theileria equi and/or Babesia caballi and has economic importance particularly in equines reared in poor management systems. This study is based on cELISA test to study the seroprevalence of EP among 370 horses and 150 donkeys in four Governorates north Egypt. Additionally, its risk factors were studied for the first time. The seroprevalence rates 36.5 %, 20 %, and 5.6 % for T. equi, B. caballi, and mixed infections, respectively. The highest antibody levels against T. equi were detected in Kafr ElSheikh (40 %) and Giza (40.1 %) Governorates, whereas thos...
Equines as reservoirs of human fascioliasis: transmission capacity, epidemiology and pathogenicity in Fasciola hepatica-infected mules.
Journal of helminthology    September 10, 2020   Volume 94 e189 doi: 10.1017/S0022149X20000693
Mera Y Sierra R, Neira G, Bargues MD, Cuervo PF, Artigas P, Logarzo L, Cortiñas G, Ibaceta DEJ, Lopez Garrido A, Bisutti E, Mas-Coma S.Fascioliasis is a zoonotic disease caused by liver flukes transmitted by freshwater lymnaeid snails. Donkey and horse reservoir roles have been highlighted in human endemic areas. Liver fluke infection in mules has received very limited research. Their role in disease transmission, epidemiological importance and Fasciola hepatica pathogenicity are studied for the first time. Prevalence was 39.5% in 81 mules from Aconcagua, and 24.4% in 127 from Uspallata, in high-altitude areas of Mendoza province, Argentina. A mean amount of 101,242 eggs/mule/day is estimated. Lymnaeids from Uspallata proved ...
Neospora caninum infection in Iran (2004-2020): A review.
Journal of parasitic diseases : official organ of the Indian Society for Parasitology    September 10, 2020   Volume 44, Issue 4 671-686 doi: 10.1007/s12639-020-01266-w
Gharekhani J, Yakhchali M, Berahmat R.Knowledge on neosporosis and associated risk factors in different species of animals are so important for designing the control programs and reduce the economic losses globally. This literature review targeted for evaluating the infection rate of in animals in Iran. Until April 2020, all of published documents in the main English and Persian-language databases were searched. A total number of 110 documents (English = 85 and Persian = 25) were extracted. Most of reports were sero-epidemiological studies using ELISA in Iranian cattle population. The range of infection was 3.8-76.2% in ...
Strangles Awareness Week: a new initiative to help stamp out strangles.
The Veterinary record    September 7, 2020   Volume 187, Issue 6 e42 doi: 10.1136/vr.m3493
Abigail McGlennon of the Animal Health Trust and Andrea Vilela of the Redwings Horse Sanctuary describe the creation and impact of a new initiative to tackle strangles in UK horses.
Equine disease surveillance: quarterly update.
The Veterinary record    September 7, 2020   Volume 187, Issue 6 e41 doi: 10.1136/vr.m3492
No abstract available
Monitoring antimicrobial resistance in bacteria isolated from horses.
The Veterinary record    September 6, 2020   Volume 187, Issue 5 186-188 doi: 10.1136/vr.m3394
Leonard F.No abstract available
Investigating the presence of equine piroplasmosis in Ireland.
The Veterinary record    September 4, 2020   Volume 187, Issue 11 e97 doi: 10.1136/vr.105937
Coultous RM, Leadon DP, Shiels BR, Sutton D, Weir W.Equine piroplasmosis (EP) is a notifiable disease in Ireland and a significant concern to domestic and international equine industries. Information regarding EP presence in Ireland is currently limited. This retrospective surveillance study describes a serological and molecular analysis of blood samples submitted to the Irish Equine Centre for EP testing between January 2013 and April 2016. Methods: Following serological testing, seropositive samples were screened using a PCR targeting the 18S ribosomal RNA gene. Amplicon sequences were bioinformatically analysed to identify the parasite speci...
Evaluation of pigment epithelium-derived factor concentration in equine amniotic membrane homogenate and its in-vitro vascular endothelial growth factor inhibition effect in tears of dogs with vascularized ulcerative keratitis.
Open veterinary journal    September 3, 2020   Volume 10, Issue 3 289-296 doi: 10.4314/ovj.v10i3.7
Villar T, Pascoli AL, Chaulagain S, Fadl-Alla BA, Martins BC.Corneal neovascularization can result from many pathological processes affecting the ocular surface leading to disturbances and opacifications that reduce corneal clarity and may impact vision. In veterinary medicine, the use of topical corticosteroid is contraindicated in the presence of ulcerative keratitis, and there is sparse research regarding safe medical alternatives to inhibit corneal neovascularization in dogs to improve visual outcome. To investigate the pigment epithelium-derived factor (PEDF) concentration in equine amniotic membrane homogenate (EAMH) and its in-vitro vascular endo...
Hendra in the Hunter Valley.
One health (Amsterdam, Netherlands)    September 2, 2020   Volume 10 100162 doi: 10.1016/j.onehlt.2020.100162
Williamson KM, Wheeler S, Kerr J, Bennett J, Freeman P, Kohlhagen J, Peel AJ, Eby P, Merritt T, Housen T, Dalton C, Durrheim DN.In June 2019 the first equine case of Hendra virus in the Hunter Valley, New South Wales, Australia was detected. An urgent human and animal health response took place, involving biosecurity measures, contact tracing, promotion of equine vaccinations and investigation of flying fox activity in the area. No human or additional animal cases occurred. Equine vaccination uptake increased by over 30-fold in the surrounding region in the three months following the case. Black flying fox and grey-headed flying fox species were detected in the Valley. The incident prompted review of Hendra virus resou...
A new equine anaesthetic mortality study two decades after CEPEF2: CEPEF4 is going live!
Equine veterinary journal    August 30, 2020   Volume 52, Issue 6 891-892 doi: 10.1111/evj.13327
Gozalo-Marcilla M, Redondo JI, Johnston M, Taylor P, Bettschart-Wolfensberger R.No abstract available
Oral Supplementation with Ultramicronized Palmitoylethanolamide for Joint Disease and Lameness Management in Four Jumping Horses: A Case Report.
Animals : an open access journal from MDPI    August 21, 2020   Volume 10, Issue 9 doi: 10.3390/ani10091469
Gugliandolo E, Barbagallo A, Peritore AF, Cuzzocrea S, Crupi R.Background: Four show jumping horses were evaluated for non-responsive lameness, which caused their withdrawal from show jumping competitions. The clinical evaluation was performed by radiographic examination, flexion tests, diagnostic anesthesia and lameness evaluation using the American Association of Equine Practitioners (AAEP) scale. The diagnoses were a case of navicular syndrome, a complicated case of chronic navicular syndrome and arthrosis of the distal interphalangeal joint of the right anterior limb and two cases of distal intertarsal joint arthritis. Nutraceuticals are often an impo...
Fatal multiple outbreaks of equine influenza H3N8 in Nigeria, 2019: The first introduction of Florida clade 1 to West Africa.
Veterinary microbiology    August 13, 2020   Volume 248 108820 doi: 10.1016/j.vetmic.2020.108820
Shittu I, Meseko CA, Sulaiman LP, Inuwa B, Mustapha M, Zakariya PS, Muhammad AA, Muhammad U, Atuman YJ, Barde IJ, Zecchin B, Quaranta EG, Shamaki D....In December 2018, suspected outbreaks of equine influenza (EI) were observed in donkeys in Sokoto State, in the extreme northwest of Nigeria bordering the Republic of the Niger. Equine influenza virus (EIV) subtype H3N8 was the etiologic agent identified in the outbreaks using real-time RT-qPCR and sequencing of both the partial haemagglutinin (HA) gene and the complete genome. Since then the H3N8 virus spread to 7 of the 19 northern states of Nigeria, where it affected both donkeys and horses. Phylogenetic analysis of the partial and complete HA gene revealed the closest nucleotide similarity...
An epidemiological survey of Theileria equi parasite in donkeys (Equus asinus) in Egypt.
Veterinary parasitology, regional studies and reports    August 13, 2020   Volume 21 100449 doi: 10.1016/j.vprsr.2020.100449
El-Sayed SAE, AbouLaila M, ElKhatam A, Abdel-Wahab A, Rizk MA.In the present study, we conducted an epidemiological survey of Theileria equi, with sequencing analysis of the PCR product using blood-DNA samples collected from donkeys (n = 149) reared in different Egyptian provinces in Lower Egypt (Menoufia and Mersa Matruh) and middle Egypt (Giza). All animals were tested for the presence of T. equi parasite using species-specific PCR assay targeting the Equi merozoite antigen-1 (EMA-1). Nine- (6.04%) samples were positive for T. equi. The highest positive rate for infection was detected in Giza zoological garden (10.16%). Egyptian EMA-1 gene sequence e...
Science-in-brief: The role of the glycocalyx in critically ill patients with reference to the horse.
Equine veterinary journal    August 12, 2020   Volume 52, Issue 6 790-793 doi: 10.1111/evj.13328
Dunkel B.No abstract available
Antiviral Medicinal Plants of Veterinary Importance: A Literature Review.
Planta medica    August 10, 2020   Volume 86, Issue 15 1058-1072 doi: 10.1055/a-1224-6115
Zitterl-Eglseer K, Marschik T.Viruses have a high mutation rate, and, thus, there is a continual emergence of new antiviral-resistant strains. Therefore, it becomes imperative to explore and develop new antiviral compounds continually. The search for pharmacological substances of plant origin that are effective against animal viruses, which have a high mortality rate or cause large economic losses, has garnered interest in the last few decades. This systematic review compiles 130 plant species that exhibit antiviral activity on 37 different virus species causing serious diseases in animals. The kind of extract, fraction, o...
Clinical insights: Equine obesity.
Equine veterinary journal    August 5, 2020   Volume 52, Issue 5 635-638 doi: 10.1111/evj.13307
Knowles EJ, Grieve L.No abstract available
Clinical insights: Musculoskeletal injury in the racehorse: What is new?
Equine veterinary journal    August 5, 2020   Volume 52, Issue 5 639-642 doi: 10.1111/evj.13309
Plevin S, McLellan J.No abstract available
Descriptive network analysis of a Standardbred horse training facility contact network: Implications for disease transmission.
The Canadian veterinary journal = La revue veterinaire canadienne    August 4, 2020   Volume 61, Issue 8 853-859 
Rossi TM, Milwid RM, Moore A, O'Sullivan TL, Greer AL.Infectious respiratory disease is a common cause of morbidity among racehorses. Quantification of contact patterns in training facilities could help inform disease prevention strategies. The study objectives were to: i) describe the contact network among horses, locations, and humans at a Standardbred horse training facility in Ontario; ii) describe the characteristics of highly influential individuals; and iii) investigate how management changes alter the network metrics and discuss the potential implications for disease transmission. Proximity loggers detected contacts among horses, staff, a...
Equine piroplasmosis: an insight into global exposure of equids from 1990 to 2019 by systematic review and meta-analysis.
Parasitology    August 3, 2020   Volume 147, Issue 13 1411-1424 doi: 10.1017/S0031182020001407
Onyiche TE, Taioe MO, Molefe NI, Biu AA, Luka J, Omeh IJ, Yokoyama N, Thekisoe O.Equine piroplasmosis (EP) is a tick-borne disease of economic importance, relevant in the international movement of equids. The causative agents are at least two apicomplexan protozoan parasites Babesia caballi and Theileria equi. To date, there is no study that estimates global and regional exposure of equids to EP. We therefore conducted a systematic review and meta-analysis to estimate the pooled prevalence and heterogeneity of EP using random-effects model. Six electronic databases were searched for publications on EP and assessed according to Preferred Reporting Items for Systematic Revie...
A first clinical case report of west nile viral encephalitis in poltava region of Ukraine.
Wiadomosci lekarskie (Warsaw, Poland : 1960)    August 1, 2020   Volume 73, Issue 4 831-834 
Kotelevska TM, Pryimenko NO, Dubynska HM, Iziumska OM, Koval TI, Pikul KV, Purdenko TY.West Nile Fever (WNF) is the most common arbovirus infection caused by West Nile Virus (WNV), which has been responsible for numerous epidemic outbreaks of disease among humans, birds and horses on all continents, with the exception of Antarctica, over the past two decades. On the territory of Ukraine, the earliest reports of cases of WNV circulation in humans and birds relate to the 70s of the XX century. In Poltava region WNF was first registered in 2011. Though the epidemiological and clinical patterns of WNF in Ukraine and Poltava region remain understudied, primarily due to the lack of al...
Bovine and equine trypanosomosis in Northwest Ethiopia: Prevalence, density of vectors and control measures.
Parasite epidemiology and control    July 31, 2020   Volume 11 e00170 doi: 10.1016/j.parepi.2020.e00170
Dagnachew S, Mohammed S, Dessie B, Tilahun M, Ayele A, Kefyalew H.A cross-sectional study was carried out from November 2016 to May 2017 in selected districts of Northwest Ethiopia (Jawi, South Achefer, Dembecha and Jabitehenan) with the aim of determining the prevalence of bovine and equine trypanosomosis, estimating the apparent density of vectors and assessing the effectiveness of control measures of the disease. A total of 1257 animals of which 803 bovine and 454 equine were examined for the determination of prevalence using blood sample collected from ear vein of animals. The buffy coat technique was employed to determine the prevalence and the packed c...
Molecular detection of 7SL-derived small RNA is a promising alternative for trypanosomosis diagnosis.
Transboundary and emerging diseases    July 31, 2020   Volume 67, Issue 6 3061-3068 doi: 10.1111/tbed.13744
Verney M, Grey F, Lemans C, Géraud T, Berthier D, Thévenon S, Rincé A, Hans A, Morrison L, Hébert L.Equine trypanosomosis comprises different parasitic diseases caused by protozoa of the subgenus Trypanozoon: Trypanosoma equiperdum (causative agent of dourine), Trypanosoma brucei (nagana) and Trypanosoma evansi (surra). Due to the absence of a vaccine and the lack of efficacy of the few available drugs, these diseases represent a major health and economic problem for international equine trade. Development of affordable, sensitive and specific diagnostic tests is therefore crucial to ensure the control of these diseases. Recently, it has been shown that a small RNA derived from the 7SL gene ...
Equine Asthma: Current Understanding and Future Directions.
Frontiers in veterinary science    July 30, 2020   Volume 7 450 doi: 10.3389/fvets.2020.00450
Couetil L, Cardwell JM, Leguillette R, Mazan M, Richard E, Bienzle D, Bullone M, Gerber V, Ivester K, Lavoie JP, Martin J, Moran G, Niedźwiedź A....The 2019 Havemeyer Workshop brought together researchers and clinicians to discuss the latest information on Equine Asthma and provide future research directions. Current clinical and molecular asthma phenotypes and endotypes in humans were discussed and compared to asthma phenotypes in horses. The role of infectious and non-infectious causes of equine asthma, genetic factors and proposed disease pathophysiology were reviewed. Diagnostic limitations were evident by the limited number of tests and biomarkers available to field practitioners. The participants emphasized the need for more accessi...
Author Correction: Detection of Neorickettsia risticii, the agent of Potomac horse fever, in horses from Rio de Janeiro, Brazil.
Scientific reports    July 29, 2020   Volume 10, Issue 1 13001 doi: 10.1038/s41598-020-69584-w
Paulino PG, Almosny N, Oliveira R, Viscardi V, Müller A, Guimarães A, Baldani C, da Silva C, Peckle M, Massard C, Santos H.An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Retrospective case series to identify the most common conditions seen ‘out-of-hours’ by first-opinion equine veterinary practitioners.
The Veterinary record    July 27, 2020   Volume 187, Issue 10 404 doi: 10.1136/vr.105880
Bowden A, Boynova P, Brennan ML, England GCW, Mair TS, Furness WA, Freeman SL, Burford JH.The study aim was to describe conditions seen 'out-of-hours' in equine practice. This was a retrospective case series of first opinion 'out-of-hours' cases seen at two equine practices between 2011 and 2013. Data were retrieved on case presentation, diagnostic testing, treatment administered and outcome, and diseases categorised using a systems-based coding system. A hierarchical logistic regression, formulated using a generalised linear model, was used to identify clinical variables associated with a binary outcome of 'critical' cases (required hospitalisation or euthanasia or died). Data fro...
Molecular detection of Coxiella burnetii in horse sera in Iran.
Comparative immunology, microbiology and infectious diseases    July 23, 2020   Volume 72 101521 doi: 10.1016/j.cimid.2020.101521
Khademi P, Ownagh A, Ataei B, Kazemnia A, Eydi J, Khalili M, M M, Mardani K.Coxiella burnetii is a zoonotic bacterium that can infect a wide range of animals including horses. However, its circulation dynamics in and through horses are still unclear. The aim of this study was to evaluate prevalence of C. burnetii and its genomic characteristics in horse sera samples in the North of Iran (Golestan Province). The samples were collected in 2018 and the age, sex, and breed of each animal were recorded. Nested-PCR was used to detect C. burnetii based on the presence of the transposable gene IS1111. The results showed that 7.50 % (P < 0.05; 95 % CI: 0.5 %-0.12 %) of the ...
Novel Equine Faecal Egg Diagnostics: Validation of the FECPAKG2.
Animals : an open access journal from MDPI    July 23, 2020   Volume 10, Issue 8 1254 doi: 10.3390/ani10081254
Tyson F, Dalesman S, Brophy PM, Morphew RM.Faecal egg counts (FECs) are the standard method of diagnosing the level of parasitic helminth egg shedding in horses and other grazing animals. Testing before treatment is an important factor in slowing the appearance of anthelmintic resistance in nematode parasites. The FECPAK, optimised for livestock, is reported to allow owners to perform FECs on their own animals without the need for a separate microscope or any specialist knowledge by tapping into remote expertise. However, the performance of the FECPAK has yet to be assessed for equids. Therefore, a comparison of the FECPAK (G2) method ...
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