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Topic:Disease Management

Disease management in horses encompasses the strategies and practices employed to prevent, control, and treat diseases affecting equine populations. This field involves understanding the etiology, transmission, and clinical presentation of various equine diseases, as well as implementing biosecurity measures and therapeutic interventions. Common diseases in horses include equine influenza, strangles, and equine herpesvirus. Effective disease management relies on accurate diagnosis, vaccination protocols, and the use of antimicrobials and other treatments. This page compiles peer-reviewed research studies and scholarly articles that explore the methodologies, challenges, and advancements in managing diseases in equine health.
Modeling equine race surface vertical mechanical behaviors in a musculoskeletal modeling environment.
Journal of biomechanics    January 19, 2015   Volume 48, Issue 4 566-572 doi: 10.1016/j.jbiomech.2015.01.006
Symons JE, Fyhrie DP, Hawkins DA, Upadhyaya SK, Stover SM.Race surfaces have been associated with the incidence of racehorse musculoskeletal injury, the leading cause of racehorse attrition. Optimal race surface mechanical behaviors that minimize injury risk are unknown. Computational models are an economical method to determine optimal mechanical behaviors. Previously developed equine musculoskeletal models utilized ground reaction floor models designed to simulate a stiff, smooth floor appropriate for a human gait laboratory. Our objective was to develop a computational race surface model (two force-displacement functions, one linear and one nonlin...
Update on Streptococcus equi subsp equi infections.
The Veterinary clinics of North America. Equine practice    January 16, 2015   Volume 31, Issue 1 27-41 doi: 10.1016/j.cveq.2014.11.003
Mallicote M.There are few diseases that ignite as much fervor among horse owners as strangles. Streptococcus equi subsp equi (strangles) infections frequently require the treating veterinarian to manage not only the clinical cases but also the biosecurity and provision of information to all involved parties. Although the disease is typically characterized by low mortality and high morbidity, restrictions of horse movement that result from appropriate quarantine procedures often frustrate the involved parties. The aims of this article are to provide clinically relevant information for diagnosis, treatment,...
Molecular characterization of equine rotaviruses isolated in Europe in 2013: implications for vaccination.
Veterinary microbiology    January 16, 2015   Volume 176, Issue 1-2 179-185 doi: 10.1016/j.vetmic.2015.01.011
Matthijnssens J, Ons E, De Coster S, Conceição-Neto N, Gryspeerdt A, Van Ranst M, Raue R.Equine group A rotavirus (RVAs) mainly cause disease in foals under the age of 3 months. Only sporadic data are available on the circulation of RVAs in equine populations in Europe. In this study, 65 diarrheic samples from foals under 4 months of age were collected in Belgium (n=32), Germany (n=17), Slovenia (n=5), Sweden (n=4), Hungary (n=3), Italy (n=2), France (n=1) and The Netherlands (n=1). Forty percent of these samples (n=26) were found to be RVA positive by a quantitative RT-PCR assay. The viral load in 11 of these samples was sufficiently high to be (partially) genotyped. G3, G14 and ...
Update on diseases and treatment of the pharynx.
The Veterinary clinics of North America. Equine practice    January 16, 2015   Volume 31, Issue 1 1-11 doi: 10.1016/j.cveq.2014.11.001
Chesen AB, Whitfield-Cargile C.This article reviews dorsal displacement of the soft palate (DDSP) and nasopharyngeal cicatrix. Palatial instability results in exercise intolerance and upper respiratory noise in performance horses. Palatial instability can progress to DDSP either permanently or only during exercise. There have been advancements related to the etiopathogensis, diagnosis, and treatment of DDSP. The laryngeal tie-forward has gained popularity and is the most widely accepted treatment option for this condition, either alone or in combination with other procedures. Nasopharyngeal cicatrix affects a small geograph...
The clinical value of whole blood point-of-care biomarkers in large animal emergency and critical care medicine.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)    January 15, 2015   Volume 25, Issue 1 138-151 doi: 10.1111/vec.12276
Radcliffe RM, Buchanan BR, Cook VL, Divers TJ.To summarize the current medical literature and provide a clinical perspective of whole blood point-of-care (POC) biomarkers in large animal emergency and critical care practice. Methods: Original studies, reviews, and textbook chapters in the human and veterinary medical fields. Conclusions: POC biomarkers are tests used to monitor normal or disease processes at or near the patient. In both human and veterinary medicine these tools are playing an increasingly important role in the management of critical diseases. The most important whole blood POC biomarkers available for veterinary practitio...
Developing best practice guidelines on equine colic.
The Veterinary record    January 13, 2015   Volume 176, Issue 2 38-40 doi: 10.1136/vr.g7688
Freeman SL, Curtis L.No abstract available
Clinical features and management of equine post operative ileus: Survey of diplomates of the European Colleges of Equine Internal Medicine (ECEIM) and Veterinary Surgeons (ECVS).
Equine veterinary journal    January 12, 2015   Volume 48, Issue 2 182-187 doi: 10.1111/evj.12355
Lefebvre D, Pirie RS, Handel IG, Tremaine WH, Hudson NP.There is a need for an improved understanding of equine post operative ileus (POI), in terms of both clinical definition and optimal management. Although the pharmacological strategies that are used to treat POI continue to evolve, little is known about the supplementary strategies used to prevent and manage this condition. Objective: To report the current strategies used to diagnose, prevent and manage POI following emergency abdominal surgeries. Methods: Cross-sectional survey. Methods: An electronic survey invitation was sent by email to 306 European college diplomates (European Colleges of...
Pathways for entry of livestock arboviruses into Great Britain: assessing the strength of evidence.
Transboundary and emerging diseases    January 12, 2015   Volume 62, Issue 2 115-123 doi: 10.1111/tbed.12317
Gale P, Kelly L, Snary EL.The emergence of bluetongue virus and Schmallenberg virus in Great Britain (GB) during the last decade has highlighted the need for understanding the relative importance of the various pathways of the entry of livestock arboviruses so as to help focus surveillance and mitigation. This study summarizes what is known for the main routes of entry and assesses the strength of the current evidence for and against. Entry through infected arthropod vectors is considered at the level of each life cycle stage for tick-, biting midge- and mosquito-borne viruses, and while there is evidence that this cou...
Vector ecology of equine piroplasmosis.
Annual review of entomology    January 8, 2015   Volume 60 561-580 doi: 10.1146/annurev-ento-010814-021110
Scoles GA, Ueti MW.Equine piroplasmosis is a disease of Equidae, including horses, donkeys, mules, and zebras, caused by either of two protozoan parasites, Theileria equi or Babesia caballi. These parasites are biologically transmitted between hosts via tick vectors, and although they have inherent differences they are categorized together because they cause similar pathology and have similar morphologies, life cycles, and vector relationships. To complete their life cycle, these parasites must undergo a complex series of developmental events, including sexual-stage development in their tick vectors. Consequentl...
Screening for anthelmintic resistance in equid strongyles (Nematoda) in Romania.
Folia parasitologica    January 1, 2015   Volume 62 2015.023 doi: 10.14411/fp.2015.023
Cernea M, Cristina RT, Stefanut LC, Madeira de Carvalho LM, Taulescu MA, Cozma V.Resistance to anthelmintic medication of equid strongyles is a worldwide phenomenon and for this reason systematic investigations of resistant parasite populations are necessary. The purpose of the present study was to investigate the presence and distribution of equid strongyles resistant to the anthelmintics used in Romania, as well as the pre-treatment and post-treatment prevalence of species of strongylid nematodes. The Faecal Egg Count Reduction Test was performed between 2010 and 2013 on a total number of 588 horses and 23 donkeys from 26 locations (subgroups). Animals of the first group...
Elimination of schistosomiasis japonica from formerly endemic areas in mountainous regions of southern China using a praziquantel regimen.
Veterinary parasitology    December 31, 2014   Volume 208, Issue 3-4 254-258 doi: 10.1016/j.vetpar.2014.12.031
Li H, Dong GD, Liu JM, Gao JX, Shi YJ, Zhang YG, Jin YM, Lu K, Cheng GF, Lin JJ.Schistosomiasis japonica is a major public health problem in China. Domestic animals play a major role in the transmission of Schistosoma japonicum to humans. To better understand the epidemiology of schistosomiasis japonica in domestic animals in the mountainous areas of China, we performed a 5-year longitudinal study of schistosomiasis in cattle and horses in Yunnan Province from 2009 to 2013. We also performed a concurrent drug-based intervention study in three settlement groups in Yunnan Province aimed at developing an effective means of controlling transmission in this region. The prevale...
Ethical animal research–a pathway to zero tolerance.
Equine veterinary journal    December 24, 2014   Volume 47, Issue 1 3-5 doi: 10.1111/evj.12390
Marr CM.No abstract available
Barking up the wrong tree: would international guidelines improve safety in equine anaesthesia?
Equine veterinary journal    December 24, 2014   Volume 47, Issue 1 14-15 doi: 10.1111/evj.12348
Senior JM.No abstract available
The management of equine acute laminitis.
Veterinary medicine (Auckland, N.Z.)    December 22, 2014   Volume 6 39-47 doi: 10.2147/VMRR.S39967
Mitchell CF, Fugler LA, Eades SC.Laminitis is an extremely painful condition resulting in damage to the soft tissues anchoring the third phalanx to the hoof, which can result in life-threatening debilitation. Specific therapy is not available. The most important principles of therapy include aggressive nutritional and medical management of primary disease processes, cryotherapy, anti-inflammatory therapy, pain management, and biomechanical support. This review focuses on the principles of evidenced-based therapies.
Equine pancreatic disease: a review and characterization of the lesions of four cases (2005-2014). Newman SJ.Equine pancreatic disease is considered rare, and successful treatment is limited. Additionally, antemortem diagnosis of equine pancreatitis is difficult because of the lack of definitive diagnostic tests. Although a paucity of information exists on this entity in the horse, pancreatic disease has typically been shown to be secondary to other gastrointestinal, hepatic, and endocrine conditions. No predisposition based on age, sex, or breed appears to exist, but several conditions predispose a horse to pancreatitis, including grain overload, endocrine disease, and parasite migration. A retrospe...
Attitudes towards implementation of surveillance-based parasite control on Kentucky Thoroughbred farms – Current strategies, awareness and willingness-to-pay.
Equine veterinary journal    December 18, 2014   Volume 47, Issue 6 694-700 doi: 10.1111/evj.12344
Robert M, Hu W, Nielsen MK, Stowe CJ.Traditionally, equine parasite control has relied heavily on frequent routine anthelmintic treatments applied at regular intervals all year round. However, current recommendations aim to employ a more surveillance-based approach and it remains unknown to what extent these recommendations are being implemented on US horse farms. Objective: To describe equine parasite control on Kentucky Thoroughbred farms and evaluate respondents' willingness to pay for various attributes of surveillance-based parasite control strategies. Methods: Questionnaire survey performed among the membership of the Kentu...
Re-emergence of a genetic outlier strain of equine arteritis virus: Impact on phylogeny.
Virus research    December 17, 2014   Volume 202 144-150 doi: 10.1016/j.virusres.2014.12.009
Steinbach F, Westcott DG, McGowan SL, Grierson SS, Frossard JP, Choudhury B.Equine arteritis virus (EAV) is the causative agent of equine viral arteritis (EVA), a respiratory and reproductive disease of equids, which is notifiable in some countries including the Great Britain (GB) and to the OIE. Herein, we present the case of a persistently infected stallion and the phylogenetic tracing of the virus strain isolated. Discussing EAV occurrence and phylogenetic analysis we review features, which may aid to harmonise and enhance the classification of EAV.
Changes in the faecal microbiota of mares precede the development of post partum colic.
Equine veterinary journal    December 14, 2014   Volume 47, Issue 6 641-649 doi: 10.1111/evj.12361
Weese JS, Holcombe SJ, Embertson RM, Kurtz KA, Roessner HA, Jalali M, Wismer SE.Disruptions in the gastrointestinal microbiota may trigger development of post partum colic. Objective: To determine the effects of the periparturient period on the faecal microbiome and identify associations between the faecal microbiota and post partum colic. Methods: Longitudinal case-control study. Methods: Pre- and post partum faecal samples were collected from mares on 3 farms in central Kentucky. Next generation sequencing of the V4 region of the 16S rRNA gene was performed on samples from 13 mares that developed colic, 13 mares that did not display colic and 5 nonpregnant controls. Res...
Role of enhanced vector transmission of a new West Nile virus strain in an outbreak of equine disease in Australia in 2011.
Parasites & vectors    December 12, 2014   Volume 7 586 doi: 10.1186/s13071-014-0586-3
van den Hurk AF, Hall-Mendelin S, Webb CE, Tan CS, Frentiu FD, Prow NA, Hall RA.In 2011, a variant of West Nile virus Kunjin strain (WNVKUN) caused an unprecedented epidemic of neurological disease in horses in southeast Australia, resulting in almost 1,000 cases and a 9% fatality rate. We investigated whether increased fitness of the virus in the primary vector, Culex annulirostris, and another potential vector, Culex australicus, contributed to the widespread nature of the outbreak. Methods: Mosquitoes were exposed to infectious blood meals containing either the virus strain responsible for the outbreak, designated WNVKUN2011, or WNVKUN2009, a strain of low virulence th...
Confirmation and quantification of clenbuterol in horse urine using liquid chromatography tandem mass spectrometry triple quadrupole.
Journal of analytical toxicology    December 11, 2014   Volume 39, Issue 2 130-132 doi: 10.1093/jat/bku140
Bishop J, Heffron B, Taddei L, Benoit M, Hurt L, Costello S, Gross M, Negrusz A.Clenbuterol (CLE) is used in horses as a bronchodilator and for its anabolic steroid-like effects. CLE is a Class 3 drug according to current Association of Racing Commissioners International (ARCI) Uniform Classification Guidelines. The Racing Medication and Testing Consortium recommended a urine CLE threshold of 140 pg/mL after careful scientific review of the results of studies describing the disposition of CLE in the horse and this threshold was adopted by the ARCI. Enzyme-linked immunosorbent assay was previously used to screen samples for CLE in Illinois, but could not detect such low co...
Identification of Suitable Areas for African Horse Sickness Virus Infections in Spanish Equine Populations.
Transboundary and emerging diseases    December 5, 2014   Volume 63, Issue 5 564-573 doi: 10.1111/tbed.12302
Sánchez-Matamoros A, Sánchez-Vizcaíno JM, Rodríguez-Prieto V, Iglesias E, Martínez-López B.African horse sickness (AHS) is one of the most important vector-borne viral infectious diseases of equines, transmitted mainly by Culicoides spp. The re-emergence of Culicoides-borne diseases in Europe, such as the recent bluetongue (BT) or Schmallenberg outbreaks, has raised concern about the potential re-introduction and further spread of AHS virus (AHSV) in Europe. Spain has one of the largest European equine populations. In addition, its geographical, environmental and entomological conditions favour AHSV infections, as shown by the historical outbreaks in the 1990s. The establishment of ...
Cylicocyclus species predominate during shortened egg reappearance period in horses after treatment with ivermectin and moxidectin.
Veterinary parasitology    December 3, 2014   Volume 206, Issue 3-4 246-252 doi: 10.1016/j.vetpar.2014.10.004
van Doorn DC, Ploeger HW, Eysker M, Geurden T, Wagenaar JA, Kooyman FN.The normal time interval between treatment of horses with a macrocyclic lactone (ML) and reappearance of strongyle eggs in the feces, or 'Egg Reappearance Period (ERP)', is at its shortest 8 weeks for ivermectin (IVM) and 12 weeks for moxidectin (MOX). Nowadays, it is not uncommon to find shorter ERPs, potentially indicating the beginning of the development of drug resistance. Whether all cyathostomin species contribute equally to a shortened ERP is not known. In the present study a Reverse Line Blot (RLB) on individual infective larvae was used to compare species composition before and after ...
Equine disease surveillance: quarterly summary.
The Veterinary record    November 29, 2014   Volume 175, Issue 21 530-533 doi: 10.1136/vr.g6835
Equine influenza in England and Scotland, Significant numbers of outbreaks of equine herpesvirus 1 neurological disease in the USA, Summary of surveillance testing, April to June 2014. These are among matters discussed in the most recent quarterly equine disease surveillance report, prepared by Defra, the Animal Health Trust and the British Equine Veterinary Association.
Focus on: Hendra virus in Australia.
The Veterinary record    November 29, 2014   Volume 175, Issue 21 533-534 doi: 10.1136/vr.g6836
Hughes K.Cases of Hendra virus infection in horses in Australia have been seen regularly since the virus was first isolated in 1994. Kristopher Hughes, associate professor of equine medicine at Charles Sturt University in Australia, gives an overview of how knowledge of the virus has developed in the past 20 years.
Hepacivirus infection in domestic horses, Brazil, 2011-2013.
Emerging infectious diseases    November 25, 2014   Volume 20, Issue 12 2180-2182 doi: 10.3201/eid2012.140603
Gemaque BS, Junior Souza de Souza A, do Carmo Pereira Soares M, Malheiros AP, Silva AL, Alves MM, Gomes-Gouvêa MS, Pinho JR....No abstract available
Spatial and temporal distribution of incidence of acquired equine polyneuropathy in Norway and Sweden, 1995-2012.
BMC veterinary research    November 15, 2014   Volume 10 265 doi: 10.1186/s12917-014-0265-9
Wolff C, Egenvall A, Hanche-Olsen S, Gröndahl G.Acquired equine polyneuropathy (AEP) is an emerging disease in horses in Sweden, Norway and Finland since 1995. Affected horses show bilateral pelvic limb knuckling and weakness, sometimes progressing to recumbency and euthanasia. The aetiology is unknown but is thought to be non-infectious and non-genetic, though possibly toxic or toxico-infectious. The objectives of this study were to describe the spatial, temporal and spatio-temporal features of AEP in Norway and Sweden for the period of 1995 to 2012. Data from all documented case farms (n = 136) were used. Space-time interaction cluste...
A Systematic Review of Recent Advances in Equine Influenza Vaccination.
Vaccines    November 14, 2014   Volume 2, Issue 4 797-831 doi: 10.3390/vaccines2040797
Paillot R.Equine influenza (EI) is a major respiratory disease of horses, which is still causing substantial outbreaks worldwide despite several decades of surveillance and prevention. Alongside quarantine procedures, vaccination is widely used to prevent or limit spread of the disease. The panel of EI vaccines commercially available is probably one of the most varied, including whole inactivated virus vaccines, Immuno-Stimulating Complex adjuvanted vaccines (ISCOM and ISCOM-Matrix), a live attenuated equine influenza virus (EIV) vaccine and a recombinant poxvirus-vectored vaccine. Several other strateg...
Strongyle infections and parasitic control strategies in German horses – a risk assessment.
BMC veterinary research    November 12, 2014   Volume 10 262 doi: 10.1186/s12917-014-0262-z
Schneider S, Pfister K, Becher AM, Scheuerle MC.As a consequence of the increasing levels of anthelmintic resistance in cyathostomes, new strategies for equine parasite control are being implemented. To assess the potential risks of these, the occurrence of strongyles was evaluated in a group of 1887 horses. The distribution of fecal egg counts (FECs), the frequency of anthelmintic drug use, and the deworming intervals were also analyzed. Between June 2012 and May 2013, 1887 fecal samples from either selectively or strategically dewormed horses were collected at 195 horse farms all over Germany and analyzed quantitatively with a modified Mc...
Equine viral arteritis.
The Veterinary clinics of North America. Equine practice    November 6, 2014   Volume 30, Issue 3 543-560 doi: 10.1016/j.cveq.2014.08.011
Balasuriya UB.Equine arteritis virus (EAV), the causative agent of equine viral arteritis (EVA), is a respiratory and reproductive disease that occurs throughout the world. EAV infection is highly species-specific and exclusively limited to members of the family Equidae, which includes horses, donkeys, mules, and zebras. EVA is an economically important disease and outbreaks could cause significant losses to the equine industry. The primary objective of this article is to summarize current understanding of EVA, specifically the disease, pathogenesis, epidemiology, host immune response, vaccination and treat...
Infectious diseases of working equids.
The Veterinary clinics of North America. Equine practice    November 6, 2014   Volume 30, Issue 3 695-718 doi: 10.1016/j.cveq.2014.09.001
Stringer AP.Most working equids reside in low-income countries where they have an essential role in the livelihoods of their owners. Numerous infectious diseases negatively impact the health and productivity of these animals. There are considerable technical, social-behavioral, and institutional impediments globally to reducing the burden of infectious diseases on working equids. One the greatest remaining challenges is the lack of funding for research, resulting from the low priority assigned to working equids by funding bodies. Changing the attitudes of decision makers will require data-driven advocacy,...
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