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Topic:Disease Prevalence

Disease prevalence in horses refers to the frequency and distribution of various diseases within equine populations. Understanding disease prevalence is essential for identifying health trends, assessing risk factors, and implementing effective disease management and prevention strategies. Common diseases affecting horses include equine influenza, equine herpesvirus, strangles, and equine infectious anemia. The study of disease prevalence involves collecting and analyzing data from veterinary reports, field studies, and laboratory diagnostics. This page compiles peer-reviewed research studies and scholarly articles that investigate the patterns, causes, and implications of disease prevalence in horses, providing insights into equine health management and epidemiology.
Selection signature analyses and genome-wide association reveal genomic hotspot regions that reflect differences between breeds of horse with contrasting risk of degenerative suspensory ligament desmitis.
G3 (Bethesda, Md.)    July 23, 2022   Volume 12, Issue 10 jkac179 doi: 10.1093/g3journal/jkac179
Momen M, Brounts SH, Binversie EE, Sample SJ, Rosa GJM, Davis BW, Muir P.Degenerative suspensory ligament desmitis is a progressive idiopathic condition that leads to scarring and rupture of suspensory ligament fibers in multiple limbs in horses. The prevalence of degenerative suspensory ligament desmitis is breed related. Risk is high in the Peruvian Horse, whereas pony and draft breeds have low breed risk. Degenerative suspensory ligament desmitis occurs in families of Peruvian Horses, but its genetic architecture has not been definitively determined. We investigated contrasts between breeds with differing risk of degenerative suspensory ligament desmitis and ide...
Low transmission rates of Equine infectious anemia virus (EIAV) in foals born to seropositive feral mares inhabiting the Amazon delta region despite climatic conditions supporting high insect vector populations.
BMC veterinary research    July 22, 2022   Volume 18, Issue 1 286 doi: 10.1186/s12917-022-03384-4
Resende CF, Santos AM, Cook RF, Victor RM, Câmara RJF, Gonçalves GP, Lima JG, Maciel E Silva AG, Leite RC, Dos Reis JKP.Marajó Island, within in the Amazon River Delta, supports numerous bands of feral equids including the genetically distinct Marajoara horses. Approximately 40% of the equids on the island are infected with Equine infectious anemia virus (EIAV). This high seropositivity rate coupled with the need to preserve rare breeds such as the Marajoara horse precludes euthanasia as the primary means for controlling EIAV in this region. In the absence of iatrogenic transmission, spread of this lentivirus is mediated primarily by hematophagous insects, whose year-round prevalence on the island is supported...
Prevalence and risk factors of epizootic lymphangitis in cart pulling horses and mules in Central and South Gondar zones, Amhara region, Ethiopia.
Heliyon    July 19, 2022   Volume 8, Issue 8 e09939 doi: 10.1016/j.heliyon.2022.e09939
Molla AM, Jemberu WT, Fentahun T.Epizootic lymphangitis (EZL) is a chronic, contagious disease of equids caused by the fungus Histoplasma capsulatum var. farciminosum. The disease is often prevalent in cart pulling equids in developing countries. This study was undertaken in Central and South Gondar zones of Amhara region, Ethiopia with the objectives of estimating the prevalence of EZL in cart pulling horses and mules and identifying the risk factors of the disease. Two towns, one high altitude and one mid altitude, from each of the two zones were included for the study. A total of 528 cart pulling horses and mules from the ...
Catastrophic Musculoskeletal Injuries in Thoroughbred Racehorses in Uruguay, 2011-2017.
Journal of equine veterinary science    July 9, 2022   Volume 117 104074 doi: 10.1016/j.jevs.2022.104074
Bimson NH, Morrice-West AV, Wong ASM, Hitchens PL, Rocca MR, Whitton RC.Catastrophic musculoskeletal injuries (CMI) pose a major welfare concern to horses and their riders, yet limited data are available describing their occurrence in South America. Using a retrospective cohort and case-control design, the objective of the study was to determine the incidence of CMI for Thoroughbreds in training and racing, and associated horse-level risk factors in Uruguay. Seventy-seven Thoroughbreds sustained a CMI, 37 of which were age- and sex-matched to 111 control horses in the same race. Training and racing data from 2011 to 2017 were collected. Incidence of race day CMI p...
Equine Histoplasmosis in Ethiopia: Phylogenetic Analysis by Sequencing of the Internal Transcribed Spacer Region of rRNA Genes.
Frontiers in cellular and infection microbiology    July 8, 2022   Volume 12 789157 doi: 10.3389/fcimb.2022.789157
Ameni G, Messele Kebede A, Zewude A, Girma Abdulla M, Asfaw R, Gobena MM, Kyalo M, Stomeo F, Gumi B, Sori T.Equine histoplasmosis commonly known as epizootic lymphangitis (EL) is a neglected granulomatous disease of equine that is endemic to Ethiopia. It is caused by variety , a dimorphic fungus that is closely related to variety c The objective of this study was to undertake a phylogenetic analysis of isolated from EL cases of horses in central Ethiopia and evaluate their relationship with isolates in other countries and/or clades using the internal transcribed spacer (ITS) region of rRNA genes. Clinical and mycological examinations, DNA extraction, polymerase chain reaction (PCR), Sanger seque...
Prevalence and whole genome-based phylogenetic, virulence and antibiotic -resistance characteristics of nasal -Staphylococcus aureus in healthy Swiss horses.
Schweizer Archiv fur Tierheilkunde    July 7, 2022   Volume 164, Issue 7 499-512 doi: 10.17236/sat00360
Hurni JI, Kaiser-Thom S, Gerber V, Keller JE, Collaud A, Fernandez J, Schwendener S, Perreten V.A total of 100 nasal swabs were collected from healthy horses in Switzerland between January 2020 and August 2020. The samples were taken from horses at 40 different stables in 12 different cantons and screened for both methicillin-resistant (MRSA) and methicillin-susceptible S. aureus (MSSA) using selective agar plates. S. aureus were tested for antibiotic susceptibility by measurement of the minimal inhibitory concentration (MIC) and for virulence factors, antibiotic resistance genes and phylogenetic characteristics using whole genome sequence analysis. Ten horses were found to be positiv...
Frequency of Detection and Prevalence Factors Associated with Common Respiratory Pathogens in Equids with Acute Onset of Fever and/or Respiratory Signs (2008-2021).
Pathogens (Basel, Switzerland)    July 2, 2022   Volume 11, Issue 7 759 doi: 10.3390/pathogens11070759
Pusterla N, James K, Barnum S, Bain F, Barnett DC, Chappell D, Gaughan E, Craig B, Schneider C, Vaala W.A voluntary biosurveillance program was established in 2008 in order to determine the shedding frequency and prevalence factors for common respiratory pathogens associated with acute onset of fever and/or respiratory signs in equids from the USA. Over a period of 13 years, a total of 10,296 equids were enrolled in the program and nasal secretions were analyzed for the qPCR detection of equine influenza virus (EIV), equine herpesvirus-1 (EHV-1), EHV-4, equine rhinitis A and B virus (ERVs), and subspecies (). Single infections with respiratory pathogens were detected in 21.1% of the submission...
Osteochondrosis (Osteochondritis Dissecans) in Lusitano Horses: Prevalence and Characteristics.
Journal of equine veterinary science    July 2, 2022   Volume 117 104063 doi: 10.1016/j.jevs.2022.104063
Ramos S, Pinto A, Crespo J, Marques JP, Bettencourt E, Gama LT, Monteiro S.Osteochondrosis (osteochondritis dissecans), OC(D), is an important joint disorder that has been studied through the years in different breeds but, to our knowledge, there are no reports of its prevalence in Lusitano horses. The aim of this study was to assess the prevalence of OC(D) in Lusitanos, define the characteristics of the disorder in this breed and compare with Spanish Purebred horses. This is a retrospective study that analysed the radiographs from the metacarpometatarsophalangeal, tarsocrural and femoropatellar joints that were taken in 302 Lusitano horses (1-12 years; obtained from...
Molecular detection and genetic characteristics of Cryptosporidium spp. in Chinese racehorses.
Equine veterinary journal    June 30, 2022   Volume 55, Issue 3 474-480 doi: 10.1111/evj.13605
Xu C, Wei Z, Tan F, Liu A, Yu F, Zhao A, Zhang L, Qi M, Zhao W.Cryptosporidium is a protozoan parasite causing diarrhoea in humans and animals. Although Cryptosporidium has been found in domestic horses (farmed or kept at pasture), there has been only one published study of Cryptosporidium infections in Chinese racehorses, which was restricted to a very small geographical area. Objective: To investigate the presence of Cryptosporidium spp. in the faeces of racehorses in China and to perform molecular characterisation of the parasite. Methods: Cross-sectional. Methods: A total of 621 fresh faecal samples were collected for DNA extraction from racehorses at...
Serological and Histopathological Investigation of Chlamydia abortus in Aborted Ewes in Wasit, Iraq.
Archives of Razi Institute    June 30, 2022   Volume 77, Issue 3 1105-1111 doi: 10.22092/ARI.2022.357270.2009
Ali HHM, Al-Bayati LH. is one of the most important pathogens, which causes a marked economic loss in small ruminants, in particular sheep, worldwide. This study aimed to detect the prevalence of in the sera of aborted ewes in Wasit province, Iraq, using the enzyme-linked immunosorbent assay (ELISA), followed by the investigation of the main histopathological alterations that occurred in some organs of the dead newborns. Out of 180 tested samples by ELISA, 32.22% of the evaluated animals showed positive reactions to IgG antibodies toward . Concerning the titers of the infection of seropositive ewes, there were sig...
Coupling spatial statistics with social network analysis to estimate distinct risk areas of disease circulation to improve risk-based surveillance.
Transboundary and emerging diseases    June 25, 2022   Volume 69, Issue 5 e2757-e2768 doi: 10.1111/tbed.14627
Cardenas NC, Sanchez F, Lopes FPN, Machado G.Most animal disease surveillance systems concentrate efforts in blocking transmission pathways and tracing back infected contacts while not considering the risk of transporting animals into areas with elevated disease risk. Here, we use a suite of spatial statistics and social network analysis to characterize animal movement among areas with an estimated distinct risk of disease circulation to ultimately enhance surveillance activities. Our model utilized equine infectious anemia virus (EIAV) outbreaks, between-farm horse movements, and spatial landscape data from 2015 through 2017. We related...
Surveillance of hepatitis E virus in the horse population of Korea: A serological and molecular approach. Yoon J, Park T, Sohn Y, Lee SK, Park BJ, Ahn HS, Go HJ, Kim DH, Lee JB, Park SY, Song CS, Lee SW, Choi IS.Hepatitis E virus (HEV) is an emerging zoonotic pathogen causing hepatitis worldwide. Despite the prevalent evidence of interspecies HEV infection in various animal species, the role of horses in HEV epidemiology remains unclear. In this study, we investigated the prevalence of HEV infection in 283 blood and 114 fecal samples from 397 horses using sandwich enzyme-linked immunosorbent assay and nested reverse transcription-polymerase chain reaction. Among the 283 serum samples, 35 were positive for anti-HEV antibodies (12.4%; 95% confidence interval: 8.8-16.8), and four of the five sampling reg...
Occurrence of Strongylid Nematode Parasites on Horse Farms in Berlin and Brandenburg, Germany, With High Seroprevalence of Strongylus vulgaris Infection.
Frontiers in veterinary science    June 10, 2022   Volume 9 892920 doi: 10.3389/fvets.2022.892920
Jürgenschellert L, Krücken J, Bousquet E, Bartz J, Heyer N, Nielsen MK, von Samson-Himmelstjerna G.The infection of horses with strongylid nematodes is highly prevalent, with multi-species infections being the rule. spp. and in particular are amongst the most pathogenic strongyle equine parasites. Presumably due to regular strategic anthelmintic treatments in combination with long prepatencies, prevalence of these worms was severely reduced in past decades. In this study, 484 horses from 48 farms in Berlin/Brandenburg, Germany were sampled between May 2017 and January 2018. Mini-FLOTAC and combined sedimentation/flotation were used to analyse faecal samples and larval cultures were carrie...
Seroprevalence of Anti-Theileria equi Antibodies in Horses from Three Geographically Distinct Areas of Romania.
Pathogens (Basel, Switzerland)    June 9, 2022   Volume 11, Issue 6 669 doi: 10.3390/pathogens11060669
Equine piroplasmosis (EP) is an endemic tick-borne disease found in most countries around the world. It affects all species of Equidae, and it is caused by Theileria equi, Babesia caballi and T. haneyi. The research herein is the second study on the prevalence of piroplasms in Romania conducted in the past two decades. The aim of this study was to assess the seroprevalence of anti-Theileria equi antibodies and the geographical distribution of this disease in the southwest, west, and northwest regions of Romania in order to obtain a more thorough understanding of the parasitological status of h...
Equine disease surveillance: quarterly update.
The Veterinary record    June 4, 2022   Volume 190, Issue 11 e1876 doi: 10.1002/vetr.1876
No abstract available
Erratum: Prevalence of and risk factors for equine glandular and squamous gastric disease in polo horses.
The Canadian veterinary journal = La revue veterinaire canadienne    June 4, 2022   Volume 63, Issue 6 626 
[This corrects the article on p. 880 in vol. 59, PMID: 30104780.].
Study on Gastrointestinal Nematodes of Equines in and around Bekoji, South Eastern Ethiopia.
Journal of parasitology research    May 30, 2022   Volume 2022 8210160 doi: 10.1155/2022/8210160
Mathewos M, Teshome D, Fesseha H.Parasitic infections can cause a variety of respiratory, intestinal, and other problems in horses, as well as contribute to some performance issues. A cross-sectional study was undertaken in and around Bekoji, South Eastern Ethiopia, from November 2020 to June 2021 to identify species and evaluate the prevalence of gastrointestinal parasites in donkeys and horses, using direct fecal smear, floatation methods, and larval cultures. In this study, the overall prevalence of gastrointestinal nematode parasites was 94.5% (363 out of 384), with donkeys accounting for 95.8% and horses accounting for 9...
Seroprevalence and Risk Factors for Equine West Nile Virus Infections in Eastern Germany, 2020.
Viruses    May 30, 2022   Volume 14, Issue 6 1191 doi: 10.3390/v14061191
Ganzenberg S, Sieg M, Ziegler U, Pfeffer M, Vahlenkamp TW, Hörügel U, Groschup MH, Lohmann KL.West Nile virus (WNV) infections were first detected in Germany in 2018, but information about WNV seroprevalence in horses is limited. The study's overall goal was to gather information that would help veterinarians, horse owners, and veterinary-, and public health- authorities understand the spread of WNV in Germany and direct protective measures. For this purpose, WNV seroprevalence was determined in counties with and without previously registered WNV infections in horses, and risk factors for seropositivity were estimated. The cohort consisted of privately owned horses from nine counties i...
Risk factors for equine trypanosomosis and hematological analysis of horses in Paraguay.
Acta tropica    May 25, 2022   Volume 233 106543 doi: 10.1016/j.actatropica.2022.106543
Yamazaki A, Suganuma K, Kayano M, Acosta TJ, Saitoh T, Valinotti MFR, Sanchez AR, Inoue N.Animal trypanosomosis, caused by Trypanozoon trypanosomes (Trypanosoma evansi and T. equiperdum), and Trypanosoma vivax, is endemic to South American countries and has a negative impact on the livestock industry. However, the risk factors for trypanosomosis in Paraguay remain unknown. This study aimed to determine the risk factors for equine trypanosomosis in Paraguay based on a PCR-based molecular survey and individual horse sampling data. In this study, 739 blood samples were collected from horses in 16 departments of Paraguay between August 2019 and November 2020. To elucidate the risk fact...
West Nile virus in the Republic of Serbia-Diagnostic performance of five serological tests in dog and horse sera.
Transboundary and emerging diseases    May 24, 2022   Volume 69, Issue 5 e2506-e2515 doi: 10.1111/tbed.14593
Vasić A, Răileanu C, Körsten C, Vojinović D, Manić M, Urošević A, Nikolić N, Dulović O, Tews BA, Petrović T, Silaghi C, Valčić M....West Nile virus (WNV) is a zoonotic mosquito-borne virus classified as family Flaviviridae and genus Flavivirus. The first WNV outbreak in humans in the Republic of Serbia was recorded in 2012. Equids and dogs can show clinical symptoms after WNV infection and are often used as sentinels. This study aimed to (i) give insight into seropositivity for WNV in clinically healthy dog and horse sera in different regions of Serbia and (ii) compare diagnostic value of 'in-house' and commercially available indirect immunofluorescence (IFA) and enzyme-linked immunoassay (ELISA) tests to 'gold standard' v...
First detection and genomic characterization of a new parvovirus in equines in China.
Archives of virology    May 16, 2022   Volume 167, Issue 7 1607-1609 doi: 10.1007/s00705-022-05455-1
Xu Y, Zhang X, Peng P, Liu Y, Yu M, Xie L.Equine copivirus (EqCoPV) is a newly discovered parvovirus that infects equines. Currently, it is unclear whether this virus is prevalent in China. In the present study, serum samples were collected from equines in China and were processed for EqCoPV DNA detection by PCR. The results demonstrated that EqCoPV was circulating among the sampled equines, with a low detection rate of 0.94%. The genome sequence of one Chinese EqCoPV strain, UH26, was determined and used for genetic and phylogenetic analysis. The results demonstrated that UH26 has a close genetic relationship to EqCoPV strains from t...
Seroprevalence and Risk Factors of African Horse Sickness in Three Agroecological Zones of Cameroon.
Veterinary medicine international    May 14, 2022   Volume 2022 2457772 doi: 10.1155/2022/2457772
Ndebé MMF, Mouiche MMM, Moffo F, Poueme RNS, Awah-Ndukum J.African horse sickness (AHS), a highly fatal arbovirosis of equines is endemic in sub-Saharan Africa. However, its epidemiology is poorly known in Cameroon. This study aimed to investigate the prevalence profile and risk factors of African horse sickness in Cameroon. Horse sera were subjected to the ELISA blocking test for the determination of antibodies against African horse sickness virus, and positive samples were submitted to capture ELISA to determine the presence of antigens. Potential risk factors associated with AHS were assessed based on the information collected in the field. The chi...
Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): antimicrobial-resistant Escherichia coli in dogs and cats, horses, swine, poultry, cattle, sheep and goats.
EFSA journal. European Food Safety Authority    May 10, 2022   Volume 20, Issue 5 e07311 doi: 10.2903/j.efsa.2022.7311
Nielsen SS, Bicout DJ, Calistri P, Canali E, Drewe JA, Garin-Bastuji B, Gonzales Rojas JL, Gortázar C, Herskin M, Michel V, Miranda Chueca MÁ.... () was identified among the most relevant antimicrobial-resistant (AMR) bacteria in the EU for dogs and cats, horses, swine, poultry, cattle, sheep and goats in previous scientific opinions. Thus, it has been assessed according to the criteria of the Animal Health Law (AHL), in particular criteria of Article 7 on disease profile and impacts, Article 5 on its eligibility to be listed, Annex IV for its categorisation according to disease prevention and control rules as in Article 9 and Article 8 for listing animal species related to the bacterium. The assessment has been performed following a m...
Prevalence of clinical signs and factors impacting expression of myosin heavy chain myopathy in Quarter Horse-related breeds with the MYH1E321G mutation.
Journal of veterinary internal medicine    April 14, 2022   Volume 36, Issue 3 1152-1159 doi: 10.1111/jvim.16417
Valberg SJ, Schultz AE, Finno CJ, Bellone RR, Hughes SS.The prevalence of clinical signs and factors triggering muscle atrophy and rhabdomyolysis associated with an MYH1 mutation in Quarter Horses and related breeds (QH) remain poorly understood. Objective: Determine the prevalence and potential triggers of atrophy and stiffness in horses homozygous reference (N/N), heterozygous (My/N), and homozygous (My/My) for the MYH1 mutation. Methods: Two-hundred seventy-five N/N, 100 My/N, and 10 My/My QH. Methods: A retrospective case-control study using a closed-ended questionnaire completed by clients of the Veterinary Genetics Laboratory at the Universit...
Molecular Detection of Equine Adenovirus 1 in Nasal Swabs from Horses in the Republic of Korea.
Veterinary sciences    April 13, 2022   Volume 9, Issue 4 187 doi: 10.3390/vetsci9040187
Lee SK, Choi J, Yoon J, Jung J, Park JY, Park J, Kim Y, Park JY, Park D.Equine adenovirus 1 (EAdV-1) can cause upper respiratory disease in horses and has been reported worldwide. In this study, and for the first time in Korea, the prevalence of EAdV-1 in equine nasal swabs was investigated using a PCR to identify potential risk factors and examine the genetic diversity of its DNA sequences by a comparison with foreign strains. Nasal swabs collected from 359 horses reared at Korea Racing Authority facilities were tested using an EAdV-1 hexon-specific PCR and the associations between EAdV-1 infection and sex, age, region, breed, and activity were analyzed. Five sam...
Factors Influencing Veterinarian Opinion on Reporting of Equine Strangles in the United States.
Journal of equine veterinary science    April 10, 2022   Volume 114 103947 doi: 10.1016/j.jevs.2022.103947
Martin KH, Redding LE, Boyle AG.Although equine strangles is reportable in all states, synchronous reporting of this disease does not occur across the country. States have variable regulations on reporting (actionable, notifiable, and monitored) and no mandatory comprehensive databases exist for tracking prevalence. In this study, we solicited veterinarians' opinions on reporting of strangles and factors influencing their opinion. Two hundred and fifty veterinarians practicing within the United States A structured survey was administered online. A total of 250 veterinarians participated: 84 participants (34%) believed that s...
The Public Health Burden of Virulent Extended-Spectrum β-Lactamase-Producing Klebsiella pneumoniae Strains Isolated from Diseased Horses.
Vector borne and zoonotic diseases (Larchmont, N.Y.)    April 7, 2022   Volume 22, Issue 4 217-224 doi: 10.1089/vbz.2022.0004
Samir A, Abdel-Moein KA, Zaher HM. has been associated with both nosocomial and community-acquired infections with mounting public health concern throughout the world. The purpose of this study was to investigate the burden of virulent extended-spectrum β-lactamase (ESBL)-producing among diarrheic horses or those with respiratory illness to underscore the public health implication of such strains. Rectal and nasal swabs were gathered from 100 diseased horses (50 diarrheic and 50 with respiratory illness). The collected swabs were processed for isolation of ESBL-producing using a selective medium followed by phenotypic and ...
Prevalence of Cryptosporidium spp. in Horses from communities of the Mapuche native people, Araucanía Region, Chile.
Equine veterinary journal    April 1, 2022   Volume 55, Issue 1 78-82 doi: 10.1111/evj.13571
Tuemmers C, Fellenberg C, Pérez EJ, Paillaqueo J.There are no studies of potential zoonotic diseases in Mapuche communities' horses. Objective: The objective of this study was to determine the prevalence of Cryptosporidium in horses of the Mapuche communities. Methods: This was a cross-sectional study. Methods: Faecal samples from 100 randomly selected horses (n = 100) were taken from rural Mapuche communities from four municipalities from the Araucanía Region. These samples were processed with the modified Ziehl-Neelsen staining technique and grouped by sex, age and municipality. Results: The general prevalence of Cryptosporidium spp. wa...
Descriptive and Time-Series Analysis of Rabies in Different Animal Species in Mexico.
Frontiers in veterinary science    April 1, 2022   Volume 9 800735 doi: 10.3389/fvets.2022.800735
Ortega-Sánchez R, Bárcenas-Reyes I, Cantó-Alarcón GJ, Luna-Cozar J, E RA, Contreras-Magallanes YG, González-Ruiz S, Cortez-García B....The spatio-temporal epidemiology of rabies has related the influence of environmental factors and anthropogenic changes on the movements of the hematophagous bat Desmodus rotundus. In Mexico, D. rotundus is the main transmitter of the rabies virus for different livestock species, modifying annually the fluctuation of the number of cases of rabies and its dissemination in subtropical areas and regions considered free of the disease. The purpose of this study was to perform a descriptive analysis of the distribution of cases of rabies in Mexico, and to perform a time-series analysis to evaluate ...
Impact of Vaccination on Rotavirus Genotype Diversity: A Nearly Two-Decade-Long Epidemiological Study before and after Rotavirus Vaccine Introduction in Sicily, Italy.
Pathogens (Basel, Switzerland)    March 31, 2022   Volume 11, Issue 4 424 doi: 10.3390/pathogens11040424
Bonura F, Mangiaracina L, Filizzolo C, Bonura C, Martella V, Ciarlet M, Giammanco GM, De Grazia S.Sicily was the first Italian region to introduce rotavirus (RV) vaccination with the monovalent G1P[8] vaccine Rotarix® in May 2012. In this study, the seasonal distribution and molecular characterization of RV strains detected over 19 years were compared to understand the effect of Rotarix® on the evolutionary dynamics of human RVs. A total of 7846 stool samples collected from children < 5 years of age, hospitalized with acute gastroenteritis, were tested for RV detection and genotyping. Since 2013, vaccine coverage has progressively increased, while the RV prevalence decreased from 36.1...
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