Topic:Disease Prevention
Disease prevention in horses encompasses strategies and practices aimed at minimizing the occurrence and spread of infectious and non-infectious diseases within equine populations. These practices include vaccination programs, biosecurity measures, and regular health monitoring. Vaccination helps to stimulate the horse's immune system to protect against specific pathogens, while biosecurity measures, such as quarantine and sanitation, reduce the risk of disease transmission. Regular health monitoring, including physical examinations and diagnostic testing, aids in early detection and management of potential health issues. This page compiles peer-reviewed research studies and scholarly articles that explore various methods and their effectiveness in preventing diseases in horses, as well as the development and implementation of prevention programs in different equine settings.
Efficacy of trivalent inactivated encephalomyelitis virus vaccine in horses. Twenty-nine horses were vaccinated with a trivalent (Venezuelan, eastern, and western) inactivated equine encephalomyelitis virus vaccine. The vaccine purchased for this study was the only one licensed and commercially available in May, 1975. Plaque-neutralizing and hemagglutinin-inhibiting antibodies in response to each of the 3 equine encephalomyelitis viruses were determined after vaccination. Horses had rising levels of plaque-neutralizing and hemagglutinin-inhibiting antibodies shortly after injection with the 1st and 2nd doses of the vaccine (given 3 weeks apart) and were refractory to c...
Study of homologous and heterologous antibody response in California horses vaccinated with attenuated Venezuelan equine encephalomyelitis vaccine (strain TC-83). Of 359 horses vaccinated with attenuated Venezuelan equine encephalomyelitis (VEE) vaccine (strain TC-83), 87% developed hemagglutination-inhibition (HI) antibodies to VEE virus within 1 month. Blood from a subsample of 101 of the 359 horses was obtained over a 1-year period. Within 1 month after vaccination, 84% of the 101 horses had developed VEE HI antibodies, 87% had developed VEE-neutralizing (Nt) antibodies, and 78% had developed VEE complement-fixing (CF) antibodies. One year after vaccination, 58% of the horses had VEE HI antibodies and 73% had VEE Nt antibodies. The percentage of hors...
Epiglottic entrapment by arytenoepiglottic folds in the horse. An abnormality of the epiglottis and arytenoepiglottic folds that caused epiglottic entrapment was diagnosed in 21 horses. Until recently, this entrapment was poorly understood. Definitive diagnosis of epiglottic entrapment can be made only by endoscopic examination of the epiglottis, arytenoepiglottic folds, and soft palate to differentiate the abnormality from dorsal displacement of the soft palate. Dorsal displacement of the soft palate is often associated with entrapped epiglottis. Epiglottic deformity, especially hypoplasia, is often associated with the entrapment. The abnormality was det...
Studies on the faecal egg output of horses after treatment with fenbendazole. Examination of faecal egg counts in horses and ponies has shown that after treatment with fenbendazole at dose levels of 7.5, 45 and 60 mg/kg, faeces remained free from strongyle eggs for periods of 6 to 18 weeks. The significance of these results is discussed in relation to routine anthelmintic treatment of horses. In particular, the activity of fenbendazole against mucosal stages of strongyle parasites allows for treatment to be recommended at less frequent intervals than when using other anthelmintics.
Vaccination against diseases associated with herpesvirus infections in animals: a review. An account is presented of the development and use of herpesvirus vaccines in domestic animals, with particular reference to those viruses causing cytolytic rather than oncogenic infections. The chief infections covered are Aujeszky's disease (AD or pseudorabies), infectious bovine rhinotracheitis (IBR) and equine rhinopneumonitis (equine abortion; EHV-1). Others mentioned are feline viral rhinotracheitis and malignant catarrhal fever of cattle. Both live-modified and inactivated vaccines are widely used or under development for ADV, IBR and EHV-1. Live vaccines are generally regarded as succe...
The long search for the causes of congenital malformations in mammals. The history of teratology is reviewed. Methods available for causing malformations in mammals by subtle changes in the environment during pregnancy are discussed. A table is provided in which the commoner teratogens are listed. Methods are described by means of which the activity of some common teratogens may be opposed. The occurrence at Battle Creek, Michigan, USA, of a chemical agent dangerous to health, life and development of all mammals is described. This gives an indication that injury and death to all mammals, as in the Sevaso disaster, including teratogenesis may be expected to be a f...
Inactivation of equine infectious anemia virus by chemical disinfectants. Twelve chemicals and commercial disinfectants were tested for inactivation of equine infectious anemia virus. In the presence of 10% bovine serum, all chemicals inactivated 4 log10 (based on 0.1 ml) of the virus within 5 minutes at 23 C. A reduction of at least 4 log10 was observed when the virus was exposed for 1 minute to substituted phenolic disinfectants (3 commercial preparations and sodium orthophenylphenate), halogen derivatives (iodophor and sodium hypochlorite), chlorhexidine, and 70% ethanol. Sodium hydroxide (5%), 2% formalin, and 2% glutaraldehyde were slower to inactivate the viru...
Studies on the antigenicity of an inactivated, aluminum hydroxide adjuvant equine influenza vaccine. An inactivated, aluminum hydroxide adjuvant equine influenza vaccine was tested in horses and guinea pigs to determine the levels of antigen that would elicit maximum serological responses. Vaccine containing serial twofold increments of A/Equi-1/Prague and A/Equi-2/Miami strains of equine influenza virus was administered to random groupings of both types of test animals. The hemagglutination inhibition antibody response for each group was then measured. Results in horses and guinea pigs were compared to determine if the equine serological values could be related to a potency test in laborator...