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Topic:Epidemiology

Epidemiology in horses involves the study of the distribution and determinants of health-related states and events in equine populations. It encompasses the investigation of patterns, causes, and effects of diseases and health conditions within horse populations. This field of study aims to identify risk factors for disease and targets for preventive healthcare. Key components of equine epidemiology include disease surveillance, outbreak investigation, and the study of disease dynamics within herds or regions. Research in this area often focuses on infectious diseases, zoonotic diseases, and the impact of environmental factors on equine health. This page compiles peer-reviewed research studies and scholarly articles that explore various aspects of epidemiology in horses, including disease prevalence, transmission pathways, and strategies for disease prevention and control.
Acute in vivo interactions of Helicobacter equorum with its equine host.
Equine veterinary journal    August 29, 2007   Volume 39, Issue 4 370-372 doi: 10.2746/042516407x206391
Moyaert H, Decostere A, Pasmans F, Baele M, Ceelen L, Smits K, Ducatelle R, Haesebrouck F.A novel urease-negative Helicobacter species has been isolated from faecal samples of clinically healthy horses, but no information is available about the main sites of colonisation in the equine gastrointestinal tract nor is the pathogenic potential of this microorganism known. An experimental infection in horses was therefore carried out. Methods: Four horses were infected with H. equorum strain CCUG 52199T and subjected to euthanasia at 10 (n = 2) and 30 days (n = 2) post inoculation. A fifth animal was inoculated with phosphate buffered saline and used as control. Gastrointestinal samples ...
A survey of horse owners in Great Britain regarding horses in their care. Part 2: Risk factors for recurrent airway obstruction.
Equine veterinary journal    August 29, 2007   Volume 39, Issue 4 301-308 doi: 10.2746/042516407x180129
Hotchkiss JW, Reid SW, Christley RM.Recurrent airway obstruction (RAO) is a commonly encountered respiratory condition of horses. Despite this, the epidemiology of this predominately manageable and reversible disease in Great Britain has been largely ignored. Objective: To estimate the prevalence of RAO in the general horse population of Great Britain and to investigate possible risk factors for RAO associated with management or early life. Methods: Horse owners were surveyed using a self-administered postal questionnaire that contained a risk-screening questionnaire (RSQ) designed to identify horses with RAO. These owners were ...
A survey of horse owners in Great Britain regarding horses in their care. Part 1: Horse demographic characteristics and management.
Equine veterinary journal    August 29, 2007   Volume 39, Issue 4 294-300 doi: 10.2746/042516407x177538
Hotchkiss JW, Reid SW, Christley RM.Information is scarce as to how horses are kept and managed in the general horse population of Great Britain. Objective: To characterise the demographics of horses in Great Britain and assess their care (with particular reference to the respiratory system). Methods: Horse owners were surveyed using a self-administered postal questionnaire. These owners were selected randomly, following geographical stratification, using 2-stage cluster sampling of veterinary practices and their clients. Results: The overall response proportion to the survey was 68.2%. An investigation of nonresponse bias detec...
Magnetic resonance imaging evaluation of 264 horses with foot pain: the podotrochlear apparatus, deep digital flexor tendon and collateral ligaments of the distal interphalangeal joint.
Equine veterinary journal    August 29, 2007   Volume 39, Issue 4 340-343 doi: 10.2746/042516407x185566
Dyson S, Murray R.To improve understanding of the interrelationships between injuries of the podotrochlear apparatus and deep digital flexor tendon (DDFT). Objective: There is a difference in frequency of different types of lesions at different anatomical sites of the DDFT. Lesions of the collateral sesamoidean ligament (CSL), distal sesamoidean impar ligament (DSIL), distal interphalangeal (DIP) joint and navicular bursa are seen in association with lesions of the navicular bone. Methods: The magnetic resonance (MR) images of 264 horses with unilateral or bilateral foot pain were analysed and graded. Descripti...
Diagnostic evaluation of real-time PCR in the detection of Rhodococcus equi in faeces and nasopharyngeal swabs from foals with pneumonia.
The Veterinary record    August 28, 2007   Volume 161, Issue 8 272-275 doi: 10.1136/vr.161.8.272
Pusterla N, Wilson WD, Mapes S, Leutenegger CM.No abstract available
Culicoides species attracted to horses with and without insect hypersensitivity.
Veterinary journal (London, England : 1997)    August 28, 2007   Volume 178, Issue 1 91-97 doi: 10.1016/j.tvjl.2007.07.005
van der Rijt R, van den Boom R, Jongema Y, van Oldruitenborgh-Oosterbaan MM.The aims of this study were to determine (1) which species of Culicoides is most commonly attracted to horses, (2) whether horses suffering insect hypersensitivity attract more Culicoides spp. than unaffected horses, and (3) the times when Culicoides spp. are most active. Horses affected by insect hypersensitivity and unaffected horses were placed inside mosquito netting tents for 30 min at different times of the day. All Culicoides spp. trapped inside the tents were collected and identified. C. obsoletus was the most common species found, followed by C. pulicaris. Healthy horses attracted sli...
Occurrence of anthelmintic resistant equine cyathostome populations in central and southern Italy.
Preventive veterinary medicine    August 24, 2007   Volume 82, Issue 3-4 314-320 doi: 10.1016/j.prevetmed.2007.07.006
Traversa D, Klei TR, Iorio R, Paoletti B, Lia RP, Otranto D, Sparagano OA, Giangaspero A.In the present survey, 276 horses bred on 16 farms located in central and southern Italy were investigated for the presence of drug resistant cyathostomes by a Fecal Egg Count Reduction Test (FECRT). Sixteen to 20 animals were selected on each farm and randomly assigned to one of four equally sized treatment groups. Groups were treated with fenbendazole, pyrantel pamoate, ivermectin or moxidectin. Resistance to fenbendazole was declared on six farms (37.5%) and suspected in two farms (12.5%), with FECR values ranging from 41% to 88.3%. Resistance to pyrantel was found in two farms (12.5%) and ...
Statistical approach to measure the efficacy of anthelmintic treatment on horse farms.
Parasitology    August 23, 2007   Volume 134, Issue Pt.14 2027-2039 doi: 10.1017/S003118200700340X
Vidyashankar AN, Kaplan RM, Chan S.Resistance to anthelmintics in gastrointestinal nematodes of livestock is a serious problem and appropriate methods are required to identify and quantify resistance. However, quantification and assessment of resistance depend on an accurate measure of treatment efficacy, and current methodologies fail to properly address the issue. The fecal egg count reduction test (FECRT) is the practical gold standard for measuring anthelmintic efficacy on farms, but these types of data are fraught with high variability that greatly impacts the accuracy of inference on efficacy. This paper develops a statis...
Equine disease surveillance, January to March 2007.
The Veterinary record    August 19, 2007   Volume 161, Issue 3 79-82 doi: 10.1136/vr.161.3.79
No abstract available
Serosurvey of West Nile virus in equids and bovids in Spain.
The Veterinary record    August 19, 2007   Volume 161, Issue 6 212 doi: 10.1136/vr.161.6.212
Jiménez-Clavero MA, Tejedor CG, Rojo G, Soriguer R, Figuerola J.No abstract available
Sequence analysis of the equid herpesvirus 2 chemokine receptor homologues E1, ORF74 and E6 demonstrates high sequence divergence between field isolates.
The Journal of general virology    August 19, 2007   Volume 88, Issue Pt 9 2450-2462 doi: 10.1099/vir.0.82942-0
Sharp EL, Farrell HE, Borchers K, Holmes EC, Davis-Poynter NJ.Equid herpesvirus 2 (EHV-2), in common with other members of the subfamily Gammaherpesvirinae, encodes homologues of cellular seven-transmembrane receptors (7TMR), namely open reading frames (ORFs) E1, 74 and E6, which each show some similarity to cellular chemokine receptors. Whereas ORF74 and E6 are members of gammaherpesvirus-conserved 7TMR gene families, E1 is currently unique to EHV-2. To investigate their genetic variability, EHV-2 7TMRs from a panel of equine gammaherpesvirus isolates were sequenced. A region of gB was sequenced to provide comparative sequence data. Phylogenetic analysi...
Prevalence of equine herpesvirus-1 infection among Thoroughbreds residing on a farm on which the virus was endemic.
Journal of the American Veterinary Medical Association    August 19, 2007   Volume 231, Issue 4 577-580 doi: 10.2460/javma.231.4.577
Brown JA, Mapes S, Ball BA, Hodder AD, Liu IK, Pusterla N.To determine the incidence of equine herpesvirus-1 (EHV-1) infection among Thoroughbreds residing on a farm on which the virus was known to be endemic. Methods: Prospective cohort study. Methods: 10 nonpregnant mares, 8 stallions, 16 weanlings, 11 racehorses, and 30 pregnant mares and their foals born during the 2006 foaling season. Methods: Blood and nasopharygeal swab samples were collected every 3 to 5 weeks for 9 months, and placenta and colostrum samples were collected at foaling. All samples were submitted for testing for EHV-1 DNA with a PCR assay. A type-specific EHV-1 ELISA was used t...
Molecular typing of Sarcocystis neurona: current status and future trends.
Veterinary parasitology    August 16, 2007   Volume 149, Issue 1-2 43-55 doi: 10.1016/j.vetpar.2007.06.039
Elsheikha HM, Mansfield LS.Sarcocystis neurona is an important protozoal pathogen because it causes the serious neurological disease equine protozoal myeloencephalitis (EPM). The capacity of this organism to cause a wide spectrum of neurological signs in horses and the broad geographic distribution of observed cases in the Americas drive the need for sensitive, reliable and rapid typing methods to characterize strains. Various molecular methods have been developed and used to diagnose EPM due to S. neurona, to identify S. neurona isolates and to determine the heterogeneity and evolutionary relatedness within this specie...
Boosting in equine influenza vaccination schedules: timing and time for a re-evaluation of requirements of national and international authorities.
Veterinary journal (London, England : 1997)    August 16, 2007   Volume 174, Issue 3 449-450 doi: 10.1016/j.tvjl.2007.06.012
Wood JL, Mumford JA, Mair TS, Slater J.No abstract available
Detection and semi-quantification of Strongylus vulgaris DNA in equine faeces by real-time quantitative PCR.
International journal for parasitology    August 14, 2007   Volume 38, Issue 3-4 443-453 doi: 10.1016/j.ijpara.2007.07.014
Nielsen MK, Peterson DS, Monrad J, Thamsborg SM, Olsen SN, Kaplan RM.Strongylus vulgaris is an important strongyle nematode with high pathogenic potential infecting horses world-wide. Several decades of intensive anthelmintic use has virtually eliminated clinical disease caused by S. vulgaris, but has also caused high levels of anthelmintic resistance in equine small strongyle (cyathostomin) nematodes. Recommendations aimed at limiting the development of anthelmintic resistance by reducing treatment intensity raises a simultaneous demand for reliable and accurate diagnostic tools for detecting important parasitic pathogens. Presently, the only means available t...
Genetic variation and phylogenetic analysis of 22 French isolates of equine arteritis virus.
Archives of virology    August 6, 2007   Volume 152, Issue 11 1977-1994 doi: 10.1007/s00705-007-1040-z
Zhang J, Miszczak F, Pronost S, Fortier C, Balasuriya UB, Zientara S, Fortier G, Timoney PJ.Genetic variation and phylogenetic relationships among 22 French isolates of equine arteritis virus (EAV) obtained over four breeding seasons (2001-2004) were determined by sequencing open reading frames (ORFs) 2a-7. The ORFs 2a-7 of 22 isolates differed from the prototype virulent Bucyrus strain of EAV by between 14 (99.5% identity) and 328 (88.7% identity) nucleotides, and differed from each other by between 0 (100% identity) and 346 (88.1% identity) nucleotides, confirming genetic diversity among EAV strains circulating in France. Phylogenetic analysis based on the partial ORF5 sequences (n...
Veterinary-care events and costs over a 5-year follow-up period for warmblooded riding horses with or without previously recorded locomotor problems in Sweden.
Preventive veterinary medicine    August 6, 2007   Volume 83, Issue 2 130-143 doi: 10.1016/j.prevetmed.2007.06.008
Egenvall A, Bonnett B, Wattle O, Emanuelson U.Our objective was to determine the amount, type and cost of veterinary care during a 5-year follow-up period, in Swedish warmblooded riding horses with and without locomotor problems as recorded in 1997. The study population comprised horses with complete insurance both for veterinary care and life during 1997. The horses were followed from the beginning of January 1998 to the end of December 2002. The exposed cohort was composed of 1558 horses that had experienced >or=1 veterinary-care event because of locomotor problems in 1997 (LP-cohort). The exposure-negative (LN) cohort was composed of 1...
Could we eradicate strangles in equids?
Journal of the American Veterinary Medical Association    August 3, 2007   Volume 231, Issue 3 377-378 doi: 10.2460/javma.231.3.377
Prescott JF, Timoney JF.No abstract available
Equine rescue and response activities in Louisiana in the aftermath of Hurricanes Katrina and Rita.
Journal of the American Veterinary Medical Association    August 3, 2007   Volume 231, Issue 3 384-392 doi: 10.2460/javma.231.3.384
McConnico RS, French DD, Clark B, Mortensen KE, Littlefield M, Moore RM.No abstract available
Adrenocorticotropin concentration following administration of thyrotropin-releasing hormone in healthy horses and those with pituitary pars intermedia dysfunction and pituitary gland hyperplasia.
Journal of the American Veterinary Medical Association    August 3, 2007   Volume 231, Issue 3 417-426 doi: 10.2460/javma.231.3.417
Beech J, Boston R, Lindborg S, Russell GE.To compare the effect of thyrotropin-releasing hormone (TRH) administration on endogenous ACTH concentrations in healthy horses and those with pituitary pars inter-media hyperplasia and compare the test with the dexamethasone suppression test (DST). Methods: Prospective case series. Methods: 15 horses with clinical signs of pituitary pars intermedia dysfunction (PPID), 4 horses with equivocal signs of PPID, and 29 horses without signs of PPID. Methods: ACTH concentrations prior to and after administration of TRH were measured 61 times in 48 horses. Results of the DST (cortisol response) were c...
An investigation of equine infectious anaemia infection in the central Anatolia region of Turkey.
Journal of the South African Veterinary Association    August 2, 2007   Volume 78, Issue 1 12-14 doi: 10.4102/jsava.v78i1.279
Yapklç O, Yavru S, Kale M, Bulut O, Simşek A, Sahna KC.In this study, 162 horses, 80 donkeys and 51 mule serum samples were collected in Konya city. Additionally, 64 horse serum samples from Ankara and 49 samples from Kayseri city were included in the study. A total of 406 serum samples were examined by agar gel immunodiffusion (AGID) and enzyme-linked immunosorbent assay (ELISA) for antibody to equine infectious anaemia virus (EIAV) and no positive result was detected.
Canine influenza virus: cross-species transmission from horses.
The Veterinary record    July 31, 2007   Volume 161, Issue 4 142-143 doi: 10.1136/vr.161.4.142-a
Newton R, Cooke A, Elton D, Bryant N, Rash A, Bowman S, Blunden T, Miller J, Hammond TA, Camm I, Day M.No abstract available
Correlation between colic and antibody levels against Anoplocephala perfoliata in horses in The Netherlands.
Tijdschrift voor diergeneeskunde    July 26, 2007   Volume 132, Issue 13 508-512 
Boswinkel M, Sloet van Oldruitenborgh-Oosterbaan MM.The importance of Anoplocephala perfoliata in horses with colic was studied in 139 horses referred for colic and 139 control horses with no signs of colic for at least three years. The serodiagnostic method of Proudman and Trees, which measures the level of A. perfoliata antibody, was used to detect A. perfoliata infection. Thirty-two horses were examined at necropsy, to determine whether the presence of A. perfoliata in the ileocaecal region was associated with the A. perfoliata antibody level. The mean A. perfoliata antibody level was significantly higher in horses with colic than in horses ...
VanA-type vancomycin-resistant enterococci in equine and swine rectal swabs and in human clinical samples.
Current microbiology    July 25, 2007   Volume 55, Issue 3 240-246 doi: 10.1007/s00284-007-0115-0
de Niederhäusern S, Sabia C, Messi P, Guerrieri E, Manicardi G, Bondi M.Vancomycin-resistant enterococci (VRE) in healthy people and in food-producing animals seems to be quite common in Europe. The existence of this community reservoir of VRE has been associated with the massive use of avoparcin in animal husbandry. Eight years after the avoparcin ban in Europe, we investigated the incidence of VanA enterococci, their resistance patterns, and the mobility of their glycopeptide-resistance determinants in a sampling of animal rectal swabs and clinical specimens. A total of 259 enterococci isolated from equine, swine, and clinical samples were subcultured on KF-stre...
Validation of computerized Swedish horse insurance data against veterinary clinical records.
Preventive veterinary medicine    July 17, 2007   Volume 82, Issue 3-4 236-251 doi: 10.1016/j.prevetmed.2007.05.020
Penell JC, Egenvall A, Bonnett BN, Pringle J.The aim was to evaluate the agreement between computerized insurance data in a large Swedish horse insurance database and the information in the corresponding clinical records (CR). A random sample of 400 veterinary care and 140 life claims was included. Information on name of the horse, breed and gender, year of birth, specific diagnosis and system diagnosis (e.g. joints, digestive and skeletal) was compared between sources. The concordance for demographic variables was categorized as agreement, disagreement or data missing. For diagnostic information, the categories were agreement, minor dis...
Evidence-based immunization in horses.
The Veterinary clinics of North America. Equine practice    July 10, 2007   Volume 23, Issue 2 481-508 doi: 10.1016/j.cveq.2007.04.003
Barquero N, Gilkerson JR, Newton JR.Evidence of vaccine efficacy is essential for practitioners when giving advice to clients about the relative merits of different vaccines or when trying to evaluate the economic benefits of instituting a vaccine program. In equine veterinary medicine, this sort of data, which are necessary to make informed decisions about vaccine use and effectiveness, are often not available. Veterinarians need to consider the epidemiology of the disease in question, the type of vaccine that they are administering to the animal, the immunologic constraints of the vaccine technology, and the available evidence...
Community-associated MRSA SCCmec type IVd in Irish equids.
The Veterinary record    July 10, 2007   Volume 161, Issue 1 35-36 doi: 10.1136/vr.161.1.35
Maeda Y, Millar BC, Loughrey A, Goldsmith CE, Rooney PJ, Moore JE, Rao J, Buckley T, Egan C, Dooley JS, Lowery CJ, Matsuda M.No abstract available
Evidence-based gastrointestinal medicine in horses: it’s not about your gut instincts.
The Veterinary clinics of North America. Equine practice    July 10, 2007   Volume 23, Issue 2 243-266 doi: 10.1016/j.cveq.2007.03.008
Nolen-Walston R, Paxson J, Ramey DW.The use of an evidence-based approach allows veterinary clinicians to assess questions that are clinically relevant to the diagnosis and treatment of equine gastrointestinal tract disease. This approach involves formulating a clinical question, searching the literature, and answering the question with the best available evidence, with the results summarized as a clinical "bottom line." This article is organized to reinforce the principle that the cornerstone of evidence-based medicine is the clinical question. Specific questions are further categorized as to topic, with epidemiologic risk fact...
Epidemiological perspectives on Hendra virus infection in horses and flying foxes.
Australian veterinary journal    July 7, 2007   Volume 85, Issue 7 268-270 doi: 10.1111/j.1751-0813.2007.00170.x
Field HE, Breed AC, Shield J, Hedlefs RM, Pittard K, Pott B, Summers PM.No abstract available
Diversity in Indian equine rotaviruses: identification of genotype G10,P6[1] and G1 strains and a new VP7 genotype (G16) strain in specimens from diarrheic foals in India.
Journal of clinical microbiology    July 7, 2007   Volume 45, Issue 7 2354 doi: 10.1128/JCM.00900-07
Gulati BR, Deepa R, Singh BK, Rao CD.No abstract available