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Topic:Equine Diseases

Equine diseases encompass a wide range of health conditions that can affect horses, including infectious diseases, metabolic disorders, and genetic conditions. These diseases can impact the overall health, performance, and well-being of horses. Common equine diseases include equine influenza, equine herpesvirus, laminitis, and equine metabolic syndrome. Diagnosis and management of these diseases often require a combination of clinical evaluation, laboratory testing, and appropriate treatment strategies. This page gathers peer-reviewed research studies and scholarly articles that explore the etiology, pathophysiology, diagnosis, and treatment options for various equine diseases, providing valuable insights for veterinarians and researchers in the field.
Electrophoretic characterization of equine oviductal fluid.
The Journal of experimental zoology    May 1, 1994   Volume 268, Issue 6 477-485 doi: 10.1002/jez.1402680608
Willis P, Sekhar KN, Brooks P, Fayrer-Hosken RA.To characterize further the events involved in fertilization and early embryonic development in the mare, effect of the estrous cycle on oviductal fluid proteins was investigated. Five mares had indwelling cannulas placed in their oviducts so that fluid could be collected throughout the estrous cycle. Daily fluid volumes were recorded and mares were monitored for signs of standing estrus. Oviductal fluid samples were pooled across mares according to stage of cycle (either estrus or nonestrus) for further analysis. Two-dimensional polyacrylamide gel electrophoresis (PAGE) was used to determine ...
Identification of phosphoseryl residues in protamines from mature mammalian spermatozoa.
Biology of reproduction    May 1, 1994   Volume 50, Issue 5 981-986 doi: 10.1095/biolreprod50.5.981
Pirhonen A, Linnala-Kankkunen A, Mäenpää PH.Protamines isolated from ejaculated human, stallion, bull, boar, and ram spermatozoa were subjected to phosphoserine conversion reaction and protein sequencing. Phosphoserines were detected as S-ethylcysteines. Endogenously phosphorylated protamines have previously been found only in ejaculated human sperm. In this study, we demonstrate that ejaculated sperm from other species also contain protamines phosphorylated at serine residues. In P1-protamines, the endogenously phosphorylated serines were located at the N-terminal region in all species studied, whereas in major forms of human and stall...
Thermoregulation in the horse in response to exercise.
The British veterinary journal    May 1, 1994   Volume 150, Issue 3 219-235 doi: 10.1016/S0007-1935(05)80003-X
Hodgson DR, Davis RE, McConaghy FF.Conversion of stored energy into mechanical energy during exercise is relatively inefficient with approximately 80% of the energy being given off as heat. Relative to many species the horse suffers an apparent disadvantage by possessing a high metabolic capacity yet a small surface area for dissipation of heat, particularly as evaporation of sweat is the major method of heat dissipation. Under most conditions of exercise at least two-thirds of the metabolic heat load is dissipated via this means with sweat losses of more than 10 l h-1 reported. The remaining exercise-induced heat load must be ...
Concentration and molecular weight distribution of hyaluronate in synovial fluid from clinically normal horses and horses with diseased joints.
American journal of veterinary research    May 1, 1994   Volume 55, Issue 5 710-715 
Tulamo RM, Heiskanen T, Salonen M.High molecular weight (MW) hyaluronate (HA) is an integral part of synovial fluid (SF), regulating many important physiologic and pathophysiologic mechanisms. Many of its effects depend on, or are reflected in, the concentration and MW of HA. High-performance liquid chromatography was used to assess simultaneously the concentration and MW of HA in SF obtained from horses with various arthritides: acute traumatic arthritis; chronic traumatic arthritis, including degenerative joint disease (DJD); and infectious arthritis. The size-exclusion column was calibrated, using appropriate HA concentrati...
Reproductive characteristics and semen quality in maiden Dutch Warmblood stallions.
Journal of reproduction and fertility    May 1, 1994   Volume 101, Issue 1 183-187 doi: 10.1530/jrf.0.1010183
Parlevliet JM, Kemp B, Colenbrander B.The semen characteristics and testicular size of 398 3-year-old maiden Dutch Warmblood stallions were studied during February and March. Mean values (+/- SD) of age (1030 +/- 88 days) and testicular size (9.8 +/- 0.9 cm) of the maiden stallions were determined as well as the following semen characteristics (mean of two ejaculates, taken 1 h apart): volume (65 +/- 26 ml), sperm concentration (2.061 +/- 1.685 x 10(8) ml-1), total number of spermatozoa (1.129 +/- 0.71 x 10(10)), percentage of progressively motile spermatozoa (68 +/- 9%), percentage of live spermatozoa with normal morphology (66 +...
Nerve supply of the proximal sesamoid bone in the horse.
The veterinary quarterly    May 1, 1994   Volume 16 Suppl 2 S66-S69 
Cornelissen BP, Rijkenhuizen AB, Kersten W, Németh F.In chronical proximal sesamoid bone lameness it is difficult to localise the exact site of pain. A specific diagnostic analgesia is not available because of a deficiency of detailed information about the nerve supply to the proximal sesamoid bones and surrounding area. A macroscopic study of the nerve distribution to the proximal sesamoid bones of 10 foals and 5 adult horses revealed that these bones are innervated by two branches, in this study called the medial and lateral sesamoidean nerve, respectively, originating from the medial and lateral palmar nerve. Histology of the left forelimbs o...
Effects of centrifugation and specimen preparation technique on bronchoalveolar lavage analysis in horses.
Equine veterinary journal    May 1, 1994   Volume 26, Issue 3 227-229 doi: 10.1111/j.2042-3306.1994.tb04374.x
Lapointe JM, Vrins A, Lavoie JP.Bronchoalveolar lavages (BAL) were performed for 6 healthy horses and 8 horses with lower airway diseases (LAD). Total cell and differential counts were performed before and after centrifugation and resuspension of the BAL cells in a small volume of fluid; there was no difference in the total cell counts, but mast cell percentages were significantly (P < 0.05) lower, after centrifugation, in the LAD group. The two specimen preparation techniques compared were cytocentrifugation and centrifugation on microscope glass covers. For both groups of horses, lymphocyte percentages were significantl...
Arthroscopic approach and intra-articular anatomy of the plantar pouch of the equine tarsocrural joint.
Veterinary surgery : VS    May 1, 1994   Volume 23, Issue 3 161-166 doi: 10.1111/j.1532-950x.1994.tb00464.x
Zamos DT, Honnas CM, Hoffman AG.Arthroscopic examination of structures within the plantar pouch of the tarsocrural joint was accomplished via portals in both the plantaromedial and plantarolateral aspects of the joint. Flexion and extension of the tarsus while examining the joint through either portal allowed observation of the proximal and plantar aspects of the lateral and medial trochlear ridges, the trochlear groove, the caudal aspect of the distal tibia, and the deep digital flexor tendon (DDFT) in its sheath. From a plantarolateral portal, the plantar talocalcaneal ligament and the plantar aspect of the lateral malleol...
Hydrops amnii in a mare.
Journal of the American Veterinary Medical Association    May 1, 1994   Volume 204, Issue 9 1481-1482 
Sertich PL, Reef VB, Oristaglio-Turner RM, Habecker PL, Maxson AD.A multiparous pregnant Welsh Pony mare was examined because of anorexia, dyspnea, and a large abdomen. Ultrasonography of the uterus revealed an excessive amount of amniotic fluid surrounding the fetus. Transabdominal ultrasonography permitted differentiation of hydrops amnii from hydrops allantois. The mare aborted a 7-month-old fetus with brachygnathia and a large, edematous umbilical cord. Hydrops amnii, an excessive accumulation of amniotic fluid in the amniotic cavity, is most commonly reported in cattle and sheep.
The relationship between intra-articular and juxta-articular intraosseous pressures in the metatarsophalangeal region of the pony.
The veterinary quarterly    May 1, 1994   Volume 16 Suppl 2 S81-S86 
Stolk PW, Firth EC.Eight metatarsophalangeal (fetlock) joints were studied in anaesthetized young ponies. Pressure measurements were made in the joint and at various sites in the marrow cavity of the third metatarsal bone with simultaneous measurement of systemic arterial and venous blood pressures. Fetlock joint flexion was always associated with a statistically significant initial decrease in intra-articular pressure (p < 0.05) followed by a marked increase in pressure (p < 0.05). Subsequent extension was accompanied by a similar pressure pattern, although there appeared to be a hysteretic relationship. ...
Clinical and force plate evaluation of the effect of a high plantar nerve block in lameness caused by induced mid-metatarsal tendinitis.
The veterinary quarterly    May 1, 1994   Volume 16 Suppl 2 S70-S75 
Keg PR, Barneveld A, Schamhardt HC, van den Belt AJ.To answer the question whether it is possible to differentiate, by means of a high plantar nerve block in the hind limb, flexor tendon lameness from a suspensory ligament lameness, mid-plantar tendinitis or desmitis was induced with collagenase in five Standardbred horses in two trials. Before the induction of lameness, and on the fourth (D4) and fourteenth day (D14) after the induction of lameness the horses were evaluated subjectively (clinical lameness score), objectively (ground reaction force (GRF) measurements), and ultrasonographically. Clinical evaluation and GRF measurements were also...
Use of clinical measurements to predict the outcome in chronic cases of grass sickness (equine dysautonomia).
The Veterinary record    April 23, 1994   Volume 134, Issue 17 438-440 doi: 10.1136/vr.134.17.438
Milne EM, Woodman MP, Doxey DL.Forty-five cases of chronic grass sickness were given scores for selected clinical measurements when they were first examined, to assess their value in predicting survival. Sixteen cases survived. The clinical scores for the degree of dysphagia, appetite, colic and the degree of reduction in gut sounds were significantly lower in the survivors than in the non-survivors. In addition, only the non-survivors had severe rhinitis. Ponies were significantly less likely to survive than cob types.
Pedunculated lipoma associated with recurrent colic in a horse.
Journal of the American Veterinary Medical Association    April 15, 1994   Volume 204, Issue 8 1163-1165 
Downes EE, Ragle CA, Hines MT.No abstract available
Partial closure of laryngotomies in horses.
Journal of the American Veterinary Medical Association    April 15, 1994   Volume 204, Issue 8 1227-1229 
Beroza GA.In horses, ventral laryngotomies are typically allowed to heal by second intention. Partial closure of the laryngotomy incision, however, was associated wtih less exudate, less aftercare, shorter hospitalization, and better cosmetic results, compared with the traditional technique. The partial closure technique did not result in complications in the 3 horses in which it was attempted.
Equine self-mutilation syndrome (57 cases).
Journal of the American Veterinary Medical Association    April 15, 1994   Volume 204, Issue 8 1219-1223 
Dodman NH, Normile JA, Shuster L, Rand W.Owners who believed they had a horse with self-mutilating behavior were asked to complete a questionnaire to obtain information on the signalment, clinical history, clinical signs, management, and treatment of the condition. Fifty-two owners of 59 horses responded; 2 cases were omitted because an organic cause was determined. Owners also were asked to complete information for unaffected horses on the same farm. Various breeds were affected, and of the 57 horses, 20 were stallions, 31 were geldings, and 6 were mares. Affected horses tended to develop the condition prior to sexual maturity. Clin...
Rapid refolding of native epitopes on the surface of cytochrome c.
Biochemistry    April 5, 1994   Volume 33, Issue 13 3967-3973 doi: 10.1021/bi00179a024
Allen MJ, Jemmerson R, Nall BT.Refolding of surface epitopes on horse cytochrome c has been measured by monoclonal antibody binding. Two antibodies were used to probe re-formation of native-like surface structure: one antibody (2B5) binds to native cytochrome c near a type II turn (residue 44) while the other (5F8) binds to a different epitope on the opposite face of the protein near the amino terminus of an alpha-helical segment (residue 60). The results show that within the first approximately 100 ms of refolding all of the unfolded protein collapses to native-like folding intermediates that contain both antibody binding ...
Update on neonatal septicemia.
The Veterinary clinics of North America. Equine practice    April 1, 1994   Volume 10, Issue 1 109-135 doi: 10.1016/s0749-0739(17)30371-1
Paradis MR.Septicemia is the second most commonly diagnosed problem in the equine neonate, superseded only by the problem of inadequate transfer of maternal antibodies. This article reviews the factors that may put a foal at high risk for developing sepsis, the diagnostic tools used to identify these animals, some of the sequelae of sepsis, and the therapeutic modalities available to the clinician.
Pharmacokinetics of ceftriaxone in mares.
Journal of veterinary pharmacology and therapeutics    April 1, 1994   Volume 17, Issue 2 155-156 doi: 10.1111/j.1365-2885.1994.tb00226.x
Gardner SY, Aucoin DP.No abstract available
Transmission of some species of internal parasites in horses born in 1990, 1991, and 1992 in the same pasture on a farm in central Kentucky.
Veterinary parasitology    April 1, 1994   Volume 52, Issue 3-4 257-269 doi: 10.1016/0304-4017(94)90117-1
Lyons ET, Tolliver SC, Stamper S, Drudge JH, Granstrom DE, Collins SS.Studies were conducted on transmission of natural infections of several species of internal parasites in horses born and kept on the same pasture on a farm in central Kentucky. Data for the first year (1989) of a 4 year study on this farm have been published recently. The present research represents the second (1990), third (1991), and fourth (1992) years of the investigation. The number of animals (n = 28) examined varied from eight born in 1990 to ten each born in 1991 and 1992. For each year, examination was made of one horse per month, beginning in June of the year of birth and extending t...
Platelet-activating factor acetylhydrolase activity in seminal plasma from the bull, stallion, rabbit, and rooster.
Biology of reproduction    April 1, 1994   Volume 50, Issue 4 912-916 doi: 10.1095/biolreprod50.4.912
Hough SR, Parks JE.Platelet-activating factor (PAF) acetylhydrolase, which inactivates PAF, has been detected in human and bovine seminal plasma and may represent a mechanism for regulating sperm-derived PAF. This study was designed to characterize further PAF acetylhydrolase in seminal plasma from domestic animal species. Sperm-free seminal plasma from the bull, stallion, rabbit, and rooster was assayed for acetylhydrolase activity based on the release of [3H]acetate from PAF. As reported previously for bull seminal plasma, activity in stallion, rabbit, and rooster seminal plasma was linear with both time and p...
Fumonisin B2 in cultured Fusarium proliferatum, M-6104, causes equine leukoencephalomalacia. Ross PF, Nelson PE, Owens DL, Rice LG, Nelson HA, Wilson TM.No abstract available
Isolation of Pasteurella canis from a foal with polyarthritis.
The Canadian veterinary journal = La revue veterinaire canadienne    April 1, 1994   Volume 35, Issue 4 244-245 
Bourgault A, Bada R, Messier S.No abstract available
[Case report of a complex odontoma in a horse–clinical picture, radiography, ultrasonography and computed tomography].
Tierarztliche Praxis    April 1, 1994   Volume 22, Issue 2 155-158 
Heufelder B, Mettenleiter E, Tietje S, Traenckner CM.The clinical signs, diagnosis and pathology of an adult horse with a complex odontoma are described. Computer tomography was shown to be a new diagnostic technique with outstanding potential in the investigation of diseases of the equine head.
An equine tetranucleotide repeat: microsatellite MPZ001.
Animal genetics    April 1, 1994   Volume 25, Issue 2 123 doi: 10.1111/j.1365-2052.1994.tb00096.x
Breen M, Downs P, Irvin Z, Bell K.No abstract available
Mucinous hyperplasia in the kidney and ureter of a horse.
Journal of comparative pathology    April 1, 1994   Volume 110, Issue 3 309-312 doi: 10.1016/s0021-9975(08)80284-8
Kim DY, Cho DY, Snider TG.A case of mucinous hyperplasia in the right renal pelvis and ureter is reported in a 23-year-old, male, Quarter horse. The affected right renal pelvis was markedly distended and filled with inspissated yellowish-green mucous material compressing the adjacent cortical and medullary parenchyma. Multiple, similar masses were present protruding from the right urethral mucosa. Histologically, the masses were characterized by a cystic glandular and papillary hyperplasia of the mucosa of the renal pelvis and ureter. This is believed to be the first reported case in an equine species.
Six equine dinucleotide repeats: microsatellites MPZ002, 3, 4, 5, 6 and 7.
Animal genetics    April 1, 1994   Volume 25, Issue 2 124 doi: 10.1111/j.1365-2052.1994.tb00097.x
Breen M, Downs P, Irvin Z, Bell K.No abstract available
Expression of functional protease and subviral particles by vaccinia virus containing equine infectious anaemia virus gag and 5′ pol genes.
The Journal of general virology    April 1, 1994   Volume 75 ( Pt 4) 895-900 doi: 10.1099/0022-1317-75-4-895
McGuire TC, O'Rourke KI, Baszler TV, Leib SR, Brassfield AL, Davis WC.Cells infected with vaccinia viruses expressing the equine infectious anaemia virus (EIAV) gag gene (VGag) or gag plus the 5' pol encoding protease (VGag/PR) were evaluated with monoclonal antibody to a p26 capsid protein linear epitope (QEISKFLTD). Both recombinant viruses expressed Gag precursor protein (55K) whereas only VGag/PR expressed a detectable Gag-Pol fusion protein (82K) with a functional protease, shown by subviral particles containing processed p26. Horses inoculated with VGag/PR produced antibodies reactive with EIAV Gag proteins.
Epidemiological investigation of equid herpesvirus-4 (EHV-4) excretion assessed by nasal swabs taken from thoroughbred foals.
Veterinary microbiology    April 1, 1994   Volume 39, Issue 3-4 275-283 doi: 10.1016/0378-1135(94)90164-3
Gilkerson J, Jorm LR, Love DN, Lawrence GL, Whalley JM.Equid herpesvirus-4 (EHV-4) was detected in nasal swabs taken from foals using a PCR based test and this information used to study the epidemiology of EHV-4 disease on three Australian Thoroughbred stud farms in NSW in 1992. There was a very high level of agreement (kappa value of 0.84) between the PCR results and virus isolation using cell culture techniques. There was a strong seasonal distribution of EHV-4 shedding. Twenty-five of 26 positive samples were collected in January and March with the remaining positive sample collected in February. Foals with clinical signs of upper respiratory t...
[Pemphigus foliaceus in a foal. A case history].
Tierarztliche Praxis    April 1, 1994   Volume 22, Issue 2 151-154 
Wohlsein P, Harps O, Trautwein G.The clinical history, clinical, pathological and immunohistological findings of a four-month-old foal with generalised pemphigus foliaceus are presented. The typical lesions of this autoimmune skin disease are described and discussed.
In-situ hybridization for demonstration of equine herpesvirus type 1 DNA in paraffin wax-embedded tissues and its use in horses with disseminated necrotizing myeloencephalitis.
Journal of comparative pathology    April 1, 1994   Volume 110, Issue 3 215-225 doi: 10.1016/s0021-9975(08)80275-7
Schmidt P, Meyer H, Hübert P, Hafner A, Andiel E, Grabner A, Dahme E.The detection of equine herpesvirus type 1 (EHV-1) in infected cell cultures, and in tissues taken at necropsy, by the in-situ hybridization technique is described. A 4.9 kb Bam HI fragment of EHV-1 vaccine strain RacH was used as a probe after labelling with [alpha-32P] thymidine 5'-triphosphate ([32P]TTP) or digoxigenin-deoxyuridine 5'-triphosphate (dUTP). Both probes specifically detected EHV-1 DNA in either cytospin or paraffin wax-embedded preparations of infected cells. The digoxigenin-labelled probe was further used to examine tissue sections of equine fetuses which had been aborted due...