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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Onset of puberty in pasture-raised Thoroughbreds born in southern hemisphere spring and autumn.
Equine veterinary journal    October 6, 2004   Volume 36, Issue 6 499-504 doi: 10.2746/0425164044877422
Brown-Douglas CG, Firth EC, Parkinson TJ, Fennessy PF.There is little information on age, weight and time of year of puberty in Thoroughbred horses, and the interpretation of such data is difficult due to the wide variety of descriptions of the onset of puberty. Objective: To examine the age, bodyweight and date of onset of puberty in Thoroughbreds born in spring and autumn. Methods: Bodyweight data and blood samples were collected in 59 pasture-raised Thoroughbred horses. Five autumn-born and 18 spring-born colts and 3 autumn-born and 33 spring-born fillies were examined from birth to age 13 and 17 months. A testosterone concentration >2 s.d. ab...
Detection of anti-diabetics in equine plasma and urine by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences    October 2, 2004   Volume 811, Issue 1 65-73 doi: 10.1016/j.jchromb.2004.03.070
Ho EN, Yiu KC, Wan TS, Stewart BD, Watkins KL.Anti-diabetics such as sulfonylurea and thiazolidinedione derivatives are hypoglycemic drugs used for the treatment of diabetes. However, they can also be used as a stopper in horseracing. This paper describes a convenient method for the separation and simultaneous detection of 10 anti-diabetic drugs (namely glipizide, glibenclamide, glimepiride, gliclazide, tolazamide, tolbutamide, nateglinide, repaglinide, rosiglitazone and pioglitazone) in equine plasma and urine by LC-MS-MS. Methods: The anti-diabetics were isolated from equine plasma and urine by liquid-liquid extraction with 1,2-dichloro...
Hippotherapy.
Physical medicine and rehabilitation clinics of North America    October 2, 2004   Volume 15, Issue 4 843-vii doi: 10.1016/j.pmr.2004.02.002
Meregillano G.Hippotherapy refers to the use of the movement of the horse asa treatment tool by physical therapists, occupational therapists,and speech-language therapists to address impairments, functional limitations, and disabilities in clients with neuromusculoskeletal dysfunction, such as cerebral palsy. Hippotherapy is used as part of an integrated treatment program to achieve functional outcomes. Hippotherapy engages the client in activities on the horse that are enjoyable and challenging. In the controlled hippotherapyenvironment, the therapist modifies the horse's movement and carefully grades sens...
Detection of stanozolol and its metabolites in equine urine by liquid chromatography-electrospray ionization ion trap mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences    October 2, 2004   Volume 811, Issue 1 75-83 doi: 10.1016/j.jchromb.2004.02.045
McKinney AR, Suann CJ, Dunstan AJ, Mulley SL, Ridley DD, Stenhouse AM.The equine phase I and phase II metabolism of the synthetic anabolic steroid stanozolol was investigated following its administration by intramuscular injection to a thoroughbred gelding. The major phase I biotransformations were hydroxylation at C16 and one other site, while phase II metabolism in the form of sulfate and beta-glucuronide conjugation was extensive. An analytical procedure was developed for the detection of stanozolol and its metabolites in equine urine using solid phase extraction, acid solvolysis of phase II conjugates and analysis by positive ion electrospray ionization ion ...
Protopine alkaloids in horse urine.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences    October 2, 2004   Volume 811, Issue 1 85-91 doi: 10.1016/j.jchromb.2004.03.077
Wynne PM, Vine JH, Amiet RG.Protopine was extracted from Fumaria officinalis and purified by column chromatography. Urine samples were collected from horses and a human volunteer that had been administered either F. officinalis or protopine free base. Plant and urine samples were acetylated and analysed by GCMS after solid-phase extraction (SPE). The urinary metabolites of protopine were identified as 4,6,7,13-tetrahydro-9,10-dihydroxy-5-methyl-benzo[e]-l,3-benzodioxolo [4,5-1][2] benzazecin-12(5H)-one, 4,6,7,13-tetrahydro-10-hydroxy-9-methoxy-5-methyl-benzo[e]-1,3-benzodioxolo[4,5-1][2] benzazecin-12(5H)-one and 4,6,7,1...
Myonecrosis and cutaneous infarction associated with Salmonella serovar Infantum infection in a horse.
Journal of the American Veterinary Medical Association    October 2, 2004   Volume 225, Issue 5 722-699 doi: 10.2460/javma.2004.225.722
Pellegrini-Masini A, Dolente BA, Habecker PL, Jesty SA.A 5-year-old Quarter Horse mare was referred for evaluation of oral ulcers, limb edema, weight loss, and weakness. There was marked diffuse swelling extending from the stifle region to the tarsal region of the left hind limb, and the horse had a left hind limb lameness. Firm swellings ranging from 2 to 15 cm in diameter and consisting of nodules, plaques, and discrete masses were palpated on both sides of the neck, over the right shoulder region, over the left elbow region, and over the left caudoventral aspect of the abdomen. Laboratory abnormalities included hypoproteinemia, neutrophilia, an...
3-Methoxytyramine as an indicator of dopaminergic manipulation in the equine athlete.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences    October 2, 2004   Volume 811, Issue 1 93-101 doi: 10.1016/j.jchromb.2004.03.078
Wynne PM, Vine JH, Amiet RG.The influence of sampling variables on the concentration of the dopamine metabolites 3-methoxytyramine (3MT), dihydroxyphenylacetic acid (DOPAC) and homovanilic acid (HVA) was examined in equine urine. A logarithmic transformation of the data for all horses gave distribution which approximated the normal distributions for each metabolite. The mean urinary concentration of 3 MT in horses was 214 ng/mL and the application of a threshold with a probability of 1 in 10,000 gave an actionable level of 4 microg/mL. Environmental variables were not forensically significant in determining the populatio...
Evaluation of early fetal loss induced by gavage with eastern tent caterpillars in pregnant mares.
Journal of the American Veterinary Medical Association    October 2, 2004   Volume 225, Issue 5 717-721 doi: 10.2460/javma.2004.225.717
Bernard WV, LeBlanc MM, Webb BA, Stromberg AJ.To determine whether gavage of pregnant mares (housed without access to pasture) with starved eastern tent caterpillars (ETCs) or their excreta is associated with early fetal loss (EFL), panophthalmitis, or pericarditis. Methods: Randomized clinical trial. Methods: 15 mares. Methods: 15 mares with fetuses from 40 to 80 days of gestation (dGa) were randomly assigned to 1 of 3 groups and received 2.5 g of ETC excreta, 50 g of starved ETCs, or 500 mL of water, respectively, once daily for 10 days. Mares were housed in box stalls, walked twice daily, and not allowed access to pasture for 12 days b...
Morphological study of the Golgi tendon organ in equine superficial digital flexor tendon.
Okajimas folia anatomica Japonica    October 1, 2004   Volume 81, Issue 2-3 33-37 doi: 10.2535/ofaj.81.33
Watanabe T, Hosaka Y, Yamamoto E, Ueda H, Tangkawattana P, Takehana K.The Golgi tendon organ (GTO) is an encapsulated fusiform mechanoreceptor siding in the musculo-tendinous junction of many animal species. Inhibitory function of afferent nerve fibers distributed from nearby motor units, the organ responds to active tension exerted onto the muscle. The morphological features of the equine GTO have not yet been elucidated. Additionally, there is some controversy regarding to the existence of the GTO in the equine superficial digital flexor tendon (SDFT). Therefore, immunohistochemistry and immunoelectron microscopy using alcian blue (pH 2.5) staining and the sil...
The use of the standard exercise test to establish the clinical significance of mild echocardiographic changes in a Thoroughbred poor performer.
Journal of the South African Veterinary Association    October 1, 2004   Volume 75, Issue 2 100-102 doi: 10.4102/jsava.v75i2.461
Meyer C, Gerber R, Guthrie AJ.A 4-year-old Thoroughbred gelding racehorse was referred to the Onderstepoort Veterinary Academic Hospital (OVAH) with a history of post-race distress and collapse. In the absence of any obvious abnormalities in the preceding diagnostic work-up, a standard exercise test was performed to determine an underlying cause for the post-race distress reported. In this particular case oxygen desaturation became evident at speeds as slow as 6 m/s, where PO2 was measured at 82.3 mm Hg. Similarly at a blood pH of 7.28, PCO2 had dropped to 30.0 mm Hg indicating a combined metabolic acidosis and respiratory...
Interrelationships among follicles during the common-growth phase of a follicular wave and capacity of individual follicles for dominance in mares.
Reproduction (Cambridge, England)    September 30, 2004   Volume 128, Issue 4 417-422 doi: 10.1530/rep.1.00259
Gastal EL, Gastal MO, Beg MA, Ginther OJ.The changing diameter interrelationships among follicles during the interval from emergence to deviation (common-growth phase) were studied in 59 mares. All follicles of > or =6.0 mm were ablated 10 days after ovulation. The four largest follicles of the postablation wave were ranked D1, D2, D3 and D4 at the expected beginning of deviation (D1 > or = 20.0 mm), according to descending diameter. The four follicles were also ranked independently, according to order of emergence at 6.0-6.9 mm as E1 (first to emerge), E2, E3 and E4. The follicles emerged during 1.3 +/- 0.1 to 3.1 +/- 0.1 days...
Natural infestation of the chewing lice (Werneckiella equi) on horses and treatment with imidacloprid and phoxim.
Parasitology research    September 30, 2004   Volume 94, Issue 5 367-370 doi: 10.1007/s00436-004-1227-0
Mencke N, Larsen KS, Eydal M, Sigurdsson H.Infestation with the chewing louse (Werneckiella (Damalinia) equi) can be found on horses world-wide. Louse infestations, including clinical signs of louse-derived dermatitis, are known from Icelandic horses. A clinical field investigation was conducted in Iceland using horses with natural louse infestations to evaluate the efficacy of imidacloprid in a 10% solution in comparison with phoxim in a 0.05% solution. A total of 27 horses received a single imidacloprid treatment using 16 ml of the 10% solution along the mane and on the dorso-lateral trunk. A further 43 horses were treated twice, 14 ...
Acute hypervolemia does not improve arterial oxygenation in maximally exercising thoroughbred horses.
European journal of applied physiology    September 29, 2004   Volume 93, Issue 4 480-488 doi: 10.1007/s00421-004-1213-3
Manohar M, Goetz TE, Hassan AS.Recently, it was reported that acute hypervolemia improves arterial oxygen tension in human athletes known to experience exercise-induced arterial hypoxemia. Since exercise-induced arterial hypoxemia is routinely observed in racehorses and is known to limit performance, we examined whether pre-exercise induction of acute hypervolemia would similarly benefit arterial oxygenation in maximally exercising thoroughbred horses. Two sets of experiments, namely, placebo [intravenous (IV) physiological saline] and acute hypervolemia (IV 7.2% NaCl, causing an 18.2% expansion of plasma volume) studies we...
Site- and exercise-related variation in structure and function of cartilage from equine distal metacarpal condyle.
Osteoarthritis and cartilage    September 29, 2004   Volume 12, Issue 10 826-833 doi: 10.1016/j.joca.2004.07.001
Nugent GE, Law AW, Wong EG, Temple MM, Bae WC, Chen AC, Kawcak CE, Sah RL.Determine (1) the site-associated response of articular cartilage of the equine distal metacarpal condyle to training at a young age as assessed by changes in indentation stiffness and alterations in cartilage structure and composition, and (2) relationships between indentation stiffness and indices of cartilage structure and composition. Methods: Experimental animals (n=6) were trained on a track (increasing exercise to 1km/day by 5 months); controls (n=6) were pasture-reared. Animals were euthanized at 18 months and four osteochondral samples were harvested per metacarpal condyle from dorsal...
Effect of hypothyroidism on the blood lipid response to higher dietary fat intake in mares.
Journal of animal science    September 28, 2004   Volume 82, Issue 9 2640-2646 doi: 10.2527/2004.8292640x
Frank N, Sojka JE, Latour MA.Blood lipid and lipoprotein concentrations were measured and compared between euthyroid and thyroidectomized mares on low-fat or high-fat diets to test the hypothesis that hypothyroidism alters the blood lipid response to higher dietary fat intake. Four healthy adult mares and four adult mares that had been thyroidectomized 3 to 6 mo earlier were placed on low-fat or high-fat diets according to a replicated 2 x 2 Latin square design consisting of two 5-wk feeding periods separated by a 2-wk washout interval. Plasma lipid concentrations were measured at 0, 3, 4, and 5 wk, and plasma lipase acti...
Glycemic index of cracked corn, oat groats and rolled barley in horses.
Journal of animal science    September 28, 2004   Volume 82, Issue 9 2623-2629 doi: 10.2527/2004.8292623x
Jose-Cunilleras E, Taylor LE, Hinchcliff KW.Muscle glycogen synthesis depends on glucose availability. This study was undertaken to determine the glycemic and insulinemic response of horses to equal amounts of hydrolyzable carbohydrates (starch and sugar) in the form of one of three grain meals or intragastric administration of a glucose solution. In a randomized crossover design, seven horses were fed each of three grain meals (cracked corn, steamed oat groats, or rolled barley) or were infused intragastrically with glucose solution at 2 g of hydrolyzable carbohydrate (starch plus sugar) per kilogram of BW. The quantity of hydrolyzable...
High-speed treadmill videoendoscopic examination of the upper respiratory tract in the horse: the results of 291 clinical cases.
Veterinary journal (London, England : 1997)    September 25, 2004   Volume 170, Issue 2 243-248 doi: 10.1016/j.tvjl.2004.06.011
Tan RH, Dowling BA, Dart AJ.The purpose of the study was to describe the prevalence of upper airway abnormalities and establish if any significant associations existed between study variables and the two most frequently identified disorders; axial deviation of the aryepiglottic folds and dorsal displacement of the soft palate. The clinical records and video-recordings of all horses referred for upper respiratory tract evaluation during high-speed treadmill videoendoscopy between November 1997 and September 2003 were reviewed. Of 291 horses included in the study, 265 underwent resting endoscopy and 42% (112/265) had a rec...
Macronutrient digestibility, nitrogen balance, plasma indicators of protein metabolism and mineral absorption in horses fed a ration rich in sugar beet pulp.
Journal of animal physiology and animal nutrition    September 25, 2004   Volume 88, Issue 9-10 321-331 doi: 10.1111/j.1439-0396.2004.00487.x
Olsman AF, Huurdeman CM, Jansen WL, Haaksma J, Sloet van Oldruitenborgh-Oosterbaan MM, Beynen AC.In a cross-over study with six mature horses, the effect of iso-energetic replacement of dietary glucose by beet pulp on macronutrient digestibility, nitrogen metabolism and mineral absorption was studied. The test ration contained 25% beet pulp in the total dietary dry matter. Beet pulp feeding significantly lowered crude fat and non-structural carbohydrate digestibility, but had no significant effect on digestibility of other macronutrients, faecal and urinary nitrogen excretion and the faecal to urinary nitrogen excretion quotient. However, on the beet pulp diet, plasma ammonia and creatini...
Effects of corn processing on the glycaemic and insulinaemic responses in horses.
Journal of animal physiology and animal nutrition    September 25, 2004   Volume 88, Issue 9-10 348-355 doi: 10.1111/j.1439-0396.2004.00491.x
Vervuert I, Coenen M, Bothe C.This study was conducted to evaluate the effects of different corn processing techniques on the glycaemic and insulinaemic responses in horses. It was hypothesized that the changes in pre-caecal starch digestibility caused by various types of corn processing would alter the post-prandial glycaemic and/or insulinaemic response. Six horses were fed in random order: untreated, finely ground, steamed, micronized, steam-flaked and popped corn. The total corn intake was adjusted to 630 g starch/horse/day (1.2-1.5 g starch/kg BW/day). During a stabilization period of 10 days, horses also received 6 k...
Phenotypic characterization of Brucella strains isolated from livestock in Nigeria.
Veterinary microbiology    September 24, 2004   Volume 103, Issue 1-2 47-53 doi: 10.1016/j.vetmic.2004.06.012
Ocholi RA, Kwaga JK, Ajogi I, Bale JO.Isolation of brucellae from aborted fetuses, hygroma fluids, milk and vaginal swabs obtained from aborting cattle, sheep, goats, pigs, and horses in Nigeria was carried out. A total of 25 isolates, obtained mainly from cattle, sheep and horses, were biotyped. All strains belonged to one species, Brucella abortus biovar 1. The epidemiological significance of this finding is discussed. Some preliminary observations on the zoonotic and public health implications of Brucella infection in Nigerian livestock are presented. A control programme involving improved management, animal movement restrictio...
[The domestic animal in heraldry; Part 3, the horse].
Historia medicinae veterinariae    September 24, 2004   Volume 28, Issue 3 84-88 
Mache C.The author presents in her paper the historical background of the heraldic. In the coming four papers she will discuss the use and position of different domestic animals in heraldic.
Back problems and lameness in horses.
The Veterinary record    September 24, 2004   Volume 155, Issue 8 248 
Cutler RS.No abstract available
Identification of reptilian and amphibian blood meals from mosquitoes in an eastern equine encephalomyelitis virus focus in central Alabama.
The American journal of tropical medicine and hygiene    September 24, 2004   Volume 71, Issue 3 272-276 
Cupp EW, Zhang D, Yue X, Cupp MS, Guyer C, Sprenger TR, Unnasch TR.Uranotaenia sapphirina, Culex erraticus, and Cx. peccator were collected in an enzootic eastern equine encephalomyelitis (EEE) virus focus in central Alabama (Tuskegee National Forest) from 2001 to 2003 and analyzed for virus as well as host selection. EEE virus was detected in each species every year except 2003, when pools of Cx. peccator were negative. Most (97%) of the 130 Cx. peccator blood meals identified were from ectothermic hosts; 3% were from birds. Among blood meals from reptiles (approximately 75% of the total), 81% were from Agkistrodon piscivorus (cottonmouth); all amphibian blo...
The detection of piroxicam, tenoxicam and their metabolites in equine urine by electrospray ionisation ion trap mass spectrometry.
Rapid communications in mass spectrometry : RCM    September 24, 2004   Volume 18, Issue 19 2338-2342 doi: 10.1002/rcm.1631
McKinney AR, Suann CJ, Stenhouse AM.An investigation has been conducted into the metabolism and urinary excretion of orally administered piroxicam and tenoxicam in the horse. The major component detected in urine after the administration of piroxicam was 5'-hydroxypiroxicam, which was detectable up to 24 h post-administration. Unchanged piroxicam was present only as a minor component. In contrast, unchanged tenoxicam was the major component observed after the administration of tenoxicam, being detectable for 72 h post-administration, while 5'-hydroxytenoxicam was a minor component. Phase II beta-glucuronide conjugation in each c...
Genetic variation within and relationships among five subpopulations of Slovak Thoroughbred.
Acta veterinaria Hungarica    September 24, 2004   Volume 52, Issue 3 259-265 doi: 10.1556/AVet.52.2004.3.2
Sátková-Jakabová D, Trandzík J, Hudecová-Kvasnáková L, Hegedüsová-Zetochová E, Bugarský A, Buleca J, Zöldág L, Jakab F, Fl'ak P.Genetic variation at six microsatellite loci was analysed for five Thoroughbred subpopulations to determine the magnitude of genetic differentiation and the genetic relationships among the subpopulations. Significant deviations from Hardy-Weinberg equilibrium were shown for a number of locus-population combinations, with all subpopulations. The genetic diversities and relationships of five Thoroughbred subpopulations were evaluated using six microsatellites recommended by the International Society of Animal Genetics (ISAG). The allele frequencies, the effective numbers of alleles, and the obse...
Shedding consistency of strongyle-type eggs in Dutch boarding horses.
Veterinary parasitology    September 24, 2004   Volume 124, Issue 3-4 249-258 doi: 10.1016/j.vetpar.2004.06.028
Döpfer D, Kerssens CM, Meijer YG, Boersema JH, Eysker M.Faeces of 484 horses were sampled twice with an interval of 6 weeks while anthelmintic therapy was halted. Faecal eggs counts revealed that 267 (55.2%) horses had consistently low numbers of eggs per gram faeces (EPG) (EPG 100). Horses with consistently high EPGs were more often mares with access to pasture, aged less than 6 or more than 23 years, that were dewormed at intervals longer than 6 months, and were treated for the last time more than 3 months before the start of the study. Horses with consistently low EPGs were more often male horses with no or limited access to pasture, that were ...
Development of a neutralizing monoclonal antibody-based blocking ELISA for detection of equine herpesvirus 1 antibodies.
Veterinary research communications    September 24, 2004   Volume 28, Issue 5 437-446 doi: 10.1023/b:verc.0000034996.18533.90
Singh BK, Ahuja S, Gulati BR.A single-dilution, sensitive and specific monoclonal antibody-based blocking enzyme-linked immunosorbent assay (B-ELISA) was developed as an alternative to the cumbersome virus neutralization test (VNT) for detection of equine herpesvirus-1 (EHV-1) antibodies. Neutralizing monoclonal antibodies (1H6 and 9C6) raised against EHV-1 (Hisar-90-7 strain) and sera from 70 horses (30 known negative and 40 known positive for EHV-1 antibodies by VNT) were used for standardization of the B-ELISA. Using a single serum dilution of 1:250 in B-ELISA, 100% specificity was obtained with both monoclonal antibod...
Apical tooth root abscesses in horses.
The Veterinary record    September 24, 2004   Volume 155, Issue 8 247 
Barbour-Hill E.No abstract available
Apical tooth root abscesses in horses.
The Veterinary record    September 24, 2004   Volume 155, Issue 8 247 
Duncanson GR.No abstract available
Identification of some new clemastine metabolites in dog, horse, and human urine with liquid chromatography/tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM    September 24, 2004   Volume 18, Issue 19 2267-2272 doi: 10.1002/rcm.1622
Tevell A, Bondesson U, Törneke K, Hedeland M.The metabolism of clemastine was studied in dogs, horses, and humans after a single dose of Tavegyl. The urine collected was extracted by solid-phase extraction or hydrolyzed with beta-glucuronidase and then extracted by liquid-liquid extraction, prior to analysis for unchanged drug and phase I and II metabolites by liquid chromatography/tandem mass spectrometry. The metabolites were identified by their molecular mass and interpretation of the product ion spectra, since no standard substances were available. Unchanged drug was recovered in urine samples from dogs and humans, but not from horse...