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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Xenogenous fertilization of equine oocytes following recovery from slaughterhouse ovaries and in vitro maturation.
Theriogenology    December 10, 2003   Volume 61, Issue 2-3 381-391 doi: 10.1016/s0093-691x(03)00221-8
Wirtu G, Bailey TL, Chauhan MS, Parker NA, Dascanio JJ, Gwazdauskas FC, Ley WB.The in vitro production (IVP) of equine embryos using currently available protocols has met limited success; therefore investigations into alternative approaches to IVP are justified. The objective of this study was to evaluate the feasibility of xenogenous fertilization and early embryo development of in vitro matured (IVM) equine oocytes. Follicular aspirations followed by slicing of ovarian tissue were performed on 202 equine ovaries obtained from an abattoir. A total of 667 oocytes (3.3 per ovary) were recovered from 1023 follicles (recovery rate, 65%). Oocytes underwent IVM for 41 +/- 2 h...
Platelets enhance endotoxin-induced monocyte tissue factor (TF) activity in the horse.
Research in veterinary science    December 9, 2003   Volume 76, Issue 1 31-35 doi: 10.1016/j.rvsc.2003.08.008
Ouellette AL, Evans RJ, Heath MF.Endotoxaemia is the leading cause of death in horses. Disseminated intravascular coagulation (DIG), stimulated by induced monocyte proteins, is a prominent feature. Monocyte-platelet cellular interactions are central to the vascular dysfunction produced by circulating endotoxin and are implicated in many thrombotic diseases in the horse. This study reports that endotoxin (0.01-10 microg ml(-1)) and blood platelets (2.5 x 10(7) - 1 x 10(8) ml(-1)) are potent inducers of expression and activity of monocyte tissue factor (TF), the primary activator of the blood coagulation protease cascade. The c...
[Epizootic equine influenza in Tunisia].
Archives de l'Institut Pasteur de Tunis    December 9, 2003   Volume 78, Issue 1-4 69-73 
Chabchoub A, Landolsi F, Zientara S, Amira A, Mejri M, Ghorbel A, Ghram A.The authors describe an equine influenza epizootic that occurred in Tunisia during February and March 1998 in the regions of Tozeur, Sousse and Tunis. They relate the symptoms, the different stages of diagnosis and the serological results.
Clinical and prognostic significance of radiographic pattern, distribution, and severity of thoracic radiographic changes in neonatal foals.
Journal of veterinary internal medicine    December 9, 2003   Volume 17, Issue 6 876-886 doi: 10.1111/j.1939-1676.2003.tb02528.x
Bedenice D, Heuwieser W, Brawer R, Solano M, Rand W, Paradis MR.A total of 207 thoracic radiographs obtained from 128 foals were evaluated to assess the impact of pulmonary radiographic pattern, distribution, and severity of pulmonary changes on short-term survival of neonatal foals. The association between selected clinical variables and the radiographic manifestation of neonatal respiratory disease was also investigated. The evaluation of interstitial and alveolar-interstitial radiographic patterns within the caudodorsal, caudoventral, and cranioventral lung regions proved to be highly reliable between viewers in the study. A diagnosis of systemic inflam...
Risk factors and prognostic variables for survival of foals with radiographic evidence of pulmonary disease.
Journal of veterinary internal medicine    December 9, 2003   Volume 17, Issue 6 868-875 doi: 10.1111/j.1939-1676.2003.tb02527.x
Bedenice D, Heuwieser W, Solano M, Rand W, Paradis MR.The medical records of 163 neonatal foals that had thoracic radiographs taken within 48 hours of admission to a referral hospital were reviewed. The objectives of this study were (1) to identify risk factors for the development of thoracic radiographic changes and (2) to identify prognostic indicators for survival in foals with radiographic evidence of pulmonary disease. Failure of transfer of passive immunity (IgG concentration < or = 400 mg/dL) was the only risk factor for radiographic evidence of respiratory disease identified by multivariate analysis. Hypoxemic patients (PaO2 1.7 mg/dL...
Clostridium novyi type A intra-abdominal abscess in a horse.
Journal of veterinary internal medicine    December 9, 2003   Volume 17, Issue 6 934-936 
Aleman M, Watson JL, Jang SS.No abstract available
A retrospective analysis of hepatic injury in horses with proximal enteritis (1984-2002).
Journal of veterinary internal medicine    December 9, 2003   Volume 17, Issue 6 896-901 doi: 10.1111/j.1939-1676.2003.tb02530.x
Davis JL, Blikslager AT, Catto K, Jones SL.The purpose of this study was to test the hypothesis that horses with proximal enteritis (PE) are predisposed to hepatic injury. We also determined whether the presence of liver injury in horses with PE was associated with other clinicopathologic abnormalities or affected outcome. The medical records of all horses admitted for evaluation of colic and gastric reflux between 1984 and 2002 were reviewed. Horses were considered to have PE if the diagnosis was made at surgery or postmortem examination or if they had clinical findings consistent with PE. Horses with a small intestinal strangulating ...
Generation and characterization of an EICP0 null mutant of equine herpesvirus 1.
Virus research    December 9, 2003   Volume 98, Issue 2 163-172 doi: 10.1016/j.virusres.2003.09.007
Yao H, Osterrieder N, O'Callaghan DJ.The EICP0 gene (gene 63) of equine herpesvirus 1 (EHV-1) encodes an early regulatory protein that is a promiscuous trans-activator of all classes of viral genes. Bacterial artificial chromosome (BAC) technology and RecE/T cloning were employed to delete the EICP0 gene from EHV-1 strain KyA. Polymerase chain reaction, Southern blot analysis, and DNA sequencing confirmed the deletion of the EICP0 gene and its replacement with a kanamycin resistance gene in mutant KyA. Transfection of rabbit kidney cells with the EICP0 mutant genome produced infectious virus, indicating that the EICP0 gene is not...
Furosemide continuous rate infusion in the horse: evaluation of enhanced efficacy and reduced side effects.
Journal of veterinary internal medicine    December 9, 2003   Volume 17, Issue 6 887-895 doi: 10.1111/j.1939-1676.2003.tb02529.x
Johansson AM, Gardner SY, Levine JF, Papich MG, LaFevers DH, Fuquay LR, Reagan VH, Atkins CE.Continuous rate infusion (CRI) of furosemide in humans is considered superior to intermittent administration (IA). This study examined whether furosemide CRI, compared with IA, would increase diuretic efficacy with decreased fluid and electrolyte fluctuations and activation of the renin-angiotensin-aldosterone system (RAAS) in the horse. Five mares were used in a crossover-design study. During a 24-hour period, each horse received a total of 3 mg/kg furosemide by either CRI (0.12 mg/kg/h preceded by a loading dose of 0.12 mg/kg IV) or IA (1 mg/kg IV q8h). There was not a statistically signific...
Hypomagnesemia in hospitalized horses.
Journal of veterinary internal medicine    December 9, 2003   Volume 17, Issue 6 860-867 doi: 10.1111/j.1939-1676.2003.tb02526.x
Johansson AM, Gardner SY, Jones SL, Fuquay LR, Reagan VH, Levine JF.This study was initiated to identify the signalment and clinical variables potentially associated with hypomagnesemia in horses evaluated at the North Carolina State University, College of Veterinary Medicine (NCSU-CVM) veterinary teaching hospital between January 1999 and May 2001. A nested case reference study (nested case-control study) was conducted to examine the potential relationship between hypomagnesemia and signalment, serum chemistry panel analyses, number of hospitalization days, discharge status, and diagnosis. A series of independent and multivariable logistic regression models w...
[Glanders–an eradicable disease–or a threat?].
Casopis lekaru ceskych    December 6, 2003   Volume 140, Issue 24 752-754 
Pospísil L.Glanders (malleus), attacking equids and transmissible to humans, does not occur in our geographical area any more, but world-wide eradication has not yet been achieved. Cases of glanders have been reported from India, Iraq, Mongolia and China and in 2001 also from South America. The disease is caused by Burkholderia mallei (earlied known as Bacillus, Pfeiferella, Loefflerella, Malleomyces, Actinobacillus, or Pseudomonas mallei). The continual interest of microbiologists in the causative agents indicates that glanders cannot be regarded as a closed historic episode. Occupational infections of ...
[Enlarged ovary in a mare: review of the literature and a case report].
Tijdschrift voor diergeneeskunde    December 6, 2003   Volume 128, Issue 22 692-696 
Westermann CM, Parlevliet JM, Meertens NM, Sloet van Oldruitenborgh-Oosterbaan MM.Mares regularly have an enlarged ovary. The main causes are haematomas, anovulatory follicles, abscesses, and neoplasia. The granulosa-theca-cell tumour is by far the most common neoplasia of the ovary (about 97%) and accounts for 2.5% of all equine tumours. In this article the differential diagnosis of an enlarged ovary and the background of granulosa-theca cell tumours are reviewed. A case is described of a mare with a very large granulosa-theca cell tumour in the left ovary, which was discovered 1 month after delivery of a healthy foal. This case is special not only because the tumour was e...
Identification of Cryptosporidium parvum ‘cattle’ genotype from a severe outbreak of neonatal foal diarrhoea.
The Veterinary record    December 5, 2003   Volume 153, Issue 20 628-631 doi: 10.1136/vr.153.20.628
Grinberg A, Oliver L, Learmonth JJ, Leyland M, Roe W, Pomroy WE.No abstract available
Anthelmintic resistance and use of anthelmintics in horses.
The Veterinary record    December 5, 2003   Volume 153, Issue 20 636 
Coles GC, Eysker M, Hodgkinson J, Matthews JB, Kaplan RM, Klei TR, Sangster NC.No abstract available
Investigation of Neospora sp. antibodies in aborted mares from Normandy, France.
Veterinary parasitology    December 5, 2003   Volume 118, Issue 1-2 1-6 doi: 10.1016/j.vetpar.2003.10.007
Pitel PH, Romand S, Pronost S, Foucher N, Gargala G, Maillard K, Thulliez P, Collobert-Laugier C, Tainturier D, Fortier G, Ballet JJ.Neospora caninum, an apicomplexan protozoan parasite, is recognized as a major cause of abortion in cattle while limited information is presently available on association between equine Neospora infections and abortions. The aim of the present study was to document prevalence of antibodies against Neospora sp. in aborted mares as a clue to the role of N. caninum in mare reproductive failure in Normandy, France. Using an agglutination test, the number of animals with elevated (>80) anti-Neospora sp. antibody titer was higher in a group of 54 aborted mares than in randomly chosen groups of 45 ma...
Influence of exogenous GnRH on sexual behavior and frozen/thawed semen viability in stallions during the non-breeding season.
Theriogenology    December 4, 2003   Volume 61, Issue 1 159-171 doi: 10.1016/s0093-691x(03)00205-x
Sieme H, Troedsson MH, Weinrich S, Klug E.Twelve fertile stallions were divided into two groups, either receiving gonadotropin-releasing hormone (GnRH) (n = 6) or Placebo (n = 6). Based on the history of frozen/thawed semen characteristics three stallions within each group were assigned as being "good freezers" [GnRH (+); Placebo (+)] and three stallions were assigned as being "poor freezers" [GnRH (-); Placebo (-)]. The study was performed as a "blinded" investigation and stallions were treated twice daily by an intramuscular injection of 1 ml GnRH (Buserelin), 50 microg) or Placebo. The experiment was divided into three time periods...
The equine thymus microenvironment: a morphological and immunohistochemical analysis.
Developmental and comparative immunology    December 4, 2003   Volume 28, Issue 3 251-264 doi: 10.1016/s0145-305x(03)00134-4
Contreiras EC, Lenzi HL, Meirelles MN, Caputo LF, Calado TJ, Villa-Verde DM, Savino W.We characterized herein the microarchitecture of the equine thymus along with post-natal development (6 months-->18 years). Thymuses showed an involutional process, beginning before the puberty and defined by five histological grades, which consider the progressive cortical thymocyte depletion, shrinkage and rearrangement of the epithelial network and increase in extracellular matrix (ECM). A second feature of the equine thymus was the presence of eosinopoiesis, erythropoiesis, mastocytopoiesis and plasmacytogenesis. Additionally, lymphatic vessels, full of lymphocytes, were particularly pr...
Liquid chromatography/electrospray ionization tandem mass spectrometric screening and confirmation methods for beta2-agonists in human or equine urine.
Journal of mass spectrometry : JMS    December 4, 2003   Volume 38, Issue 11 1197-1206 doi: 10.1002/jms.542
Thevis M, Opfermann G, Schänzer W.Electrospray ionization (ESI) mass spectra of 19 common beta(2)-agonists were investigated in terms of fragmentation pattern and dissociation behavior of the analytes, proving the origin of fragment ions and indicating mechanisms of charge-driven and charge-remote fragmentation. Based on these data, liquid chromatographic/ESI tandem mass spectrometric (LC/ESI-MS/MS) screening and confirmation methods were developed for doping control purposes. These procedures employ established sample preparation steps including either acidic or enzymatic hydrolysis, alkaline extraction and, in the case of eq...
Oral susceptibility of South African Culicoides species to live-attenuated serotype-specific vaccine strains of African horse sickness virus (AHSV).
Medical and veterinary entomology    December 4, 2003   Volume 17, Issue 4 436-447 doi: 10.1111/j.1365-2915.2003.00467.x
Paweska JT, Prinsloo S, Venter GJ.The oral susceptibility of livestock-associated South African Culicoides midges (Diptera: Ceratopogonidae) to infection with the tissue culture-attenuated vaccine strains of African horse sickness virus (AHSV) currently in use is reported. Field-collected Culicoides were fed on horse blood-virus mixtures each containing one of the seven serotype-specific vaccine strains of AHSV, namely serotypes 1, 2, 3, 4, 6, 7 and 8. The mean titres of virus in the bloodmeals for the seven vaccine strains were between 6.8 and 7.6 log10TCID50/mL. All females (n = 3262) that survived 10 days extrinsic incubati...
[Population genetic analysis of the heritability of gutteral pouch tympany in Arabian purebred foals].
DTW. Deutsche tierarztliche Wochenschrift    December 4, 2003   Volume 110, Issue 10 417-419 
Blazyczek I, Hamann H, Ohnesorge B, Deegen E, Distl O.The objective of the present study was to analyse the importance of the influences of the sex, inbreeding coefficient and the additive genetic contribution to the occurrence of guttural pouch tympany in Arabian foals. Horses affected by guttural pouch tympany were ascertained in the Clinic for Horses, School of Veterinary Medicine Hannover. The data comprised 27 Arabian purebred foals with guttural pouch tympany. Of these 27 animals 22 were patients of the Clinic for Horses between 1994 and 2001 and 5 Arabian foals were sampled on the studs. Information on the pedigrees of these patients allow...
Intra- and intermolecular disulfide bonds of the GP2b glycoprotein of equine arteritis virus: relevance for virus assembly and infectivity.
Journal of virology    December 4, 2003   Volume 77, Issue 24 12996-13004 doi: 10.1128/jvi.77.24.12996-13004.2003
Wieringa R, De Vries AA, Post SM, Rottier PJ.Equine arteritis virus (EAV) is an enveloped, positive-strand RNA virus belonging to the family Arteriviridae of the order NIDOVIRALES: EAV virions contain six different envelope proteins. The glycoprotein GP(5) (previously named G(L)) and the unglycosylated membrane protein M are the major envelope proteins, while the glycoproteins GP(2b) (previously named G(S)), GP(3), and GP(4) are minor structural proteins. The unglycosylated small hydrophobic envelope protein E is present in virus particles in intermediate molar amounts compared to the other transmembrane proteins. The GP(5) and M protein...
Seasonal dynamics of the Cayenne tick, Amblyomma cajennense on horses in Brazil.
Medical and veterinary entomology    December 4, 2003   Volume 17, Issue 4 412-416 doi: 10.1111/j.1365-2915.2003.00459.x
Oliveira PR, Borges LM, Leite RC, Freitas CM.The population dynamics of all stages of the Cayenne tick, Amblyomma cajennense (Fabricius) (Acari: Ixodidae) on horses was evaluated over a period of 2 years in the district of Pedro Leopoldo, State of Minas Gerais, Brazil. Every 14 days, the left side of 20 horses was brushed for collection of immature stages; counts of adults were also undertaken. Infestation by larvae was detected from April to August, whereas nymphs were observed from June to October. Infestation by adults was detected throughout the year, and the highest population density occurred from September to March. The number of ...
Quantification and age-related distribution of articular cartilage degeneration in the equine fetlock joint.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 697-701 doi: 10.2746/042516403775696357
Brommer H, van Weeren PR, Brama PA, Barneveld A.The equine fetlock joint has the largest number of traumatic and degenerative lesions of all joints of the appendicular skeleton. Objective: To gain insight into the distribution of cartilage degeneration across the articular surface in relation to age in order better to understand the dynamic nature and progression of osteoarthritis (OA). Objective: That there would be a specific age-related distribution pattern of cartilage degeneration in the equine metacarpophalangeal joint. Methods: The proximal articular cartilage surfaces of the first phalanges (P1) of 73 slaughter horses (age range 0.4...
Life-threatening hemorrhage from enterotomies and anastomoses in 7 horses.
Veterinary surgery : VS    December 3, 2003   Volume 32, Issue 6 553-558 doi: 10.1111/j.1532-950x.2003.00553.x
Doyle AJ, Freeman DE, Rapp H, Murrell JA, Wilkins PA.To report our experience with horses that presumptively had severe intraluminal hemorrhage from enterotomy or anastomosis. Methods: Clinical study. Methods: Six adult horses and 1 adult donkey. Methods: A retrospective study was conducted at the University of Illinois (April 1994 to December 2001) to determine the clinical course and outcome of horses with melena and/or anemia and evidence of life-threatening hemorrhage from intestinal incisions. Medical records of all horses that had colic surgery were reviewed to determine the proportion of horses with this complication. In addition, horses ...
Evaluation of Carolina Rinse solution as a treatment for ischaemia reperfusion of the equine jejunum.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 642-646 doi: 10.2746/042516403775696302
Dabareiner RM, White NA, Donaldson L.Ileus and peritoneal adhesions are the most common complications following surgery for small intestinal obstruction. Carolina Rinse (CR) has been shown to decrease reperfusion injury in intestine and other organs. Objective: CR decreases intestinal inflammation and subsequent scarring associated with reperfusion injury. Methods: CR was infused intra-arterially and applied topically just prior to reperfusion in jejunum exposed to experimental ischemia. Vascular permeability, neutrophil accumulation and serosal scarring were compared in treated and untreated intestine. Results: CR maintained a n...
The efficacy of dantrolene sodium in controlling exertional rhabdomyolysis in the Thoroughbred racehorse.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 707-711 doi: 10.2746/042516403775696221
Edwards JG, Newtont JR, Ramzan PH, Pilsworth RC, Shepherd MC.Dantrolene sodium (Dantrium) has been used extensively for the treatment of myopathies in man and anecdotal evidence suggests it is of clinical benefit in the control of exercise-induced rhabdomyolysis (ER) in racehorses, although data to support this are currently lacking. Objective: To investigate the efficacy of oral dantrolene sodium in controlling ER in a randomised, double-blind, placebo-controlled crossover trial involving 77 Thoroughbred racehorses in Newmarket, UK. Methods: Horses were treated on 2 occasions 1 week apart, with treatment days coinciding with a return to exercise follow...
Antemortem diagnosis of equine mesothelioma by pleural biopsy.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 723-727 doi: 10.2746/042516403775696375
Fry MM, Magdesian KG, Judy CE, Pusterla N, Vidal JD, Pesavento RA, Zinkl JG.No abstract available
Biomechanical investigation of the association between suspensory ligament injury and lateral condylar fracture in thoroughbred racehorses.
Veterinary surgery : VS    December 3, 2003   Volume 32, Issue 6 585-597 doi: 10.1111/j.1532-950x.2003.00585.x
Le Jeune SS, Macdonald MH, Stover SM, Taylor KT, Gerdes M.Objective-To determine whether partial transection of the medial branch of the suspensory ligament (MBSL) alters equine third metacarpal bone (MC3) condylar surface strains and forelimb, distal joint angles in a manner consistent with promotion of lateral condylar fracture. Study Design-In vitro biomechanical experiment. Sample Population-Right forelimbs from 7 Thoroughbred horse cadavers. Methods-Lateral and medial MC3 condylar, dorsal and abaxial, bone surface strains and distal joint angles were measured both before and after partial transection of the MBSL during in vitro axial limb compre...
Ultrasonography of the equine cervical region: a descriptive study in eight horses.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 647-655 doi: 10.2746/042516403775696311
Berg LC, Nielsen JV, Thoefner MB, Thomsen PD.In equine patients, the cause of clinical signs possibly related to the cervical region is often difficult to diagnose. Ultrasonography allows quick and noninvasive visualisation, but reference material of the normal equine neck is needed. Objective: To describe and document the normal ultrasonographic appearance of transverse scans in the cervical region with emphasis on the synovial articular facet joints, cervical vertebrae and paravertebral structures; and further, to provide images of frozen cross-sections for anatomical reference. Methods: A study describing the normal ultrasonographic a...
Clinical evidence: an avenue to evidence-based medicine.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 634-635 doi: 10.2746/042516403775696267
Rossdale PD, Jeffcott LB, Holmes MA.No abstract available