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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Identification of Cryptosporidium parvum ‘cattle’ genotype from a severe outbreak of neonatal foal diarrhoea.
The Veterinary record    December 5, 2003   Volume 153, Issue 20 628-631 doi: 10.1136/vr.153.20.628
Grinberg A, Oliver L, Learmonth JJ, Leyland M, Roe W, Pomroy WE.No abstract available
Anthelmintic resistance and use of anthelmintics in horses.
The Veterinary record    December 5, 2003   Volume 153, Issue 20 636 
Coles GC, Eysker M, Hodgkinson J, Matthews JB, Kaplan RM, Klei TR, Sangster NC.No abstract available
Investigation of Neospora sp. antibodies in aborted mares from Normandy, France.
Veterinary parasitology    December 5, 2003   Volume 118, Issue 1-2 1-6 doi: 10.1016/j.vetpar.2003.10.007
Pitel PH, Romand S, Pronost S, Foucher N, Gargala G, Maillard K, Thulliez P, Collobert-Laugier C, Tainturier D, Fortier G, Ballet JJ.Neospora caninum, an apicomplexan protozoan parasite, is recognized as a major cause of abortion in cattle while limited information is presently available on association between equine Neospora infections and abortions. The aim of the present study was to document prevalence of antibodies against Neospora sp. in aborted mares as a clue to the role of N. caninum in mare reproductive failure in Normandy, France. Using an agglutination test, the number of animals with elevated (>80) anti-Neospora sp. antibody titer was higher in a group of 54 aborted mares than in randomly chosen groups of 45 ma...
Influence of exogenous GnRH on sexual behavior and frozen/thawed semen viability in stallions during the non-breeding season.
Theriogenology    December 4, 2003   Volume 61, Issue 1 159-171 doi: 10.1016/s0093-691x(03)00205-x
Sieme H, Troedsson MH, Weinrich S, Klug E.Twelve fertile stallions were divided into two groups, either receiving gonadotropin-releasing hormone (GnRH) (n = 6) or Placebo (n = 6). Based on the history of frozen/thawed semen characteristics three stallions within each group were assigned as being "good freezers" [GnRH (+); Placebo (+)] and three stallions were assigned as being "poor freezers" [GnRH (-); Placebo (-)]. The study was performed as a "blinded" investigation and stallions were treated twice daily by an intramuscular injection of 1 ml GnRH (Buserelin), 50 microg) or Placebo. The experiment was divided into three time periods...
The equine thymus microenvironment: a morphological and immunohistochemical analysis.
Developmental and comparative immunology    December 4, 2003   Volume 28, Issue 3 251-264 doi: 10.1016/s0145-305x(03)00134-4
Contreiras EC, Lenzi HL, Meirelles MN, Caputo LF, Calado TJ, Villa-Verde DM, Savino W.We characterized herein the microarchitecture of the equine thymus along with post-natal development (6 months-->18 years). Thymuses showed an involutional process, beginning before the puberty and defined by five histological grades, which consider the progressive cortical thymocyte depletion, shrinkage and rearrangement of the epithelial network and increase in extracellular matrix (ECM). A second feature of the equine thymus was the presence of eosinopoiesis, erythropoiesis, mastocytopoiesis and plasmacytogenesis. Additionally, lymphatic vessels, full of lymphocytes, were particularly pr...
Liquid chromatography/electrospray ionization tandem mass spectrometric screening and confirmation methods for beta2-agonists in human or equine urine.
Journal of mass spectrometry : JMS    December 4, 2003   Volume 38, Issue 11 1197-1206 doi: 10.1002/jms.542
Thevis M, Opfermann G, Schänzer W.Electrospray ionization (ESI) mass spectra of 19 common beta(2)-agonists were investigated in terms of fragmentation pattern and dissociation behavior of the analytes, proving the origin of fragment ions and indicating mechanisms of charge-driven and charge-remote fragmentation. Based on these data, liquid chromatographic/ESI tandem mass spectrometric (LC/ESI-MS/MS) screening and confirmation methods were developed for doping control purposes. These procedures employ established sample preparation steps including either acidic or enzymatic hydrolysis, alkaline extraction and, in the case of eq...
Oral susceptibility of South African Culicoides species to live-attenuated serotype-specific vaccine strains of African horse sickness virus (AHSV).
Medical and veterinary entomology    December 4, 2003   Volume 17, Issue 4 436-447 doi: 10.1111/j.1365-2915.2003.00467.x
Paweska JT, Prinsloo S, Venter GJ.The oral susceptibility of livestock-associated South African Culicoides midges (Diptera: Ceratopogonidae) to infection with the tissue culture-attenuated vaccine strains of African horse sickness virus (AHSV) currently in use is reported. Field-collected Culicoides were fed on horse blood-virus mixtures each containing one of the seven serotype-specific vaccine strains of AHSV, namely serotypes 1, 2, 3, 4, 6, 7 and 8. The mean titres of virus in the bloodmeals for the seven vaccine strains were between 6.8 and 7.6 log10TCID50/mL. All females (n = 3262) that survived 10 days extrinsic incubati...
[Population genetic analysis of the heritability of gutteral pouch tympany in Arabian purebred foals].
DTW. Deutsche tierarztliche Wochenschrift    December 4, 2003   Volume 110, Issue 10 417-419 
Blazyczek I, Hamann H, Ohnesorge B, Deegen E, Distl O.The objective of the present study was to analyse the importance of the influences of the sex, inbreeding coefficient and the additive genetic contribution to the occurrence of guttural pouch tympany in Arabian foals. Horses affected by guttural pouch tympany were ascertained in the Clinic for Horses, School of Veterinary Medicine Hannover. The data comprised 27 Arabian purebred foals with guttural pouch tympany. Of these 27 animals 22 were patients of the Clinic for Horses between 1994 and 2001 and 5 Arabian foals were sampled on the studs. Information on the pedigrees of these patients allow...
Intra- and intermolecular disulfide bonds of the GP2b glycoprotein of equine arteritis virus: relevance for virus assembly and infectivity.
Journal of virology    December 4, 2003   Volume 77, Issue 24 12996-13004 doi: 10.1128/jvi.77.24.12996-13004.2003
Wieringa R, De Vries AA, Post SM, Rottier PJ.Equine arteritis virus (EAV) is an enveloped, positive-strand RNA virus belonging to the family Arteriviridae of the order NIDOVIRALES: EAV virions contain six different envelope proteins. The glycoprotein GP(5) (previously named G(L)) and the unglycosylated membrane protein M are the major envelope proteins, while the glycoproteins GP(2b) (previously named G(S)), GP(3), and GP(4) are minor structural proteins. The unglycosylated small hydrophobic envelope protein E is present in virus particles in intermediate molar amounts compared to the other transmembrane proteins. The GP(5) and M protein...
Seasonal dynamics of the Cayenne tick, Amblyomma cajennense on horses in Brazil.
Medical and veterinary entomology    December 4, 2003   Volume 17, Issue 4 412-416 doi: 10.1111/j.1365-2915.2003.00459.x
Oliveira PR, Borges LM, Leite RC, Freitas CM.The population dynamics of all stages of the Cayenne tick, Amblyomma cajennense (Fabricius) (Acari: Ixodidae) on horses was evaluated over a period of 2 years in the district of Pedro Leopoldo, State of Minas Gerais, Brazil. Every 14 days, the left side of 20 horses was brushed for collection of immature stages; counts of adults were also undertaken. Infestation by larvae was detected from April to August, whereas nymphs were observed from June to October. Infestation by adults was detected throughout the year, and the highest population density occurred from September to March. The number of ...
The efficacy of dantrolene sodium in controlling exertional rhabdomyolysis in the Thoroughbred racehorse.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 707-711 doi: 10.2746/042516403775696221
Edwards JG, Newtont JR, Ramzan PH, Pilsworth RC, Shepherd MC.Dantrolene sodium (Dantrium) has been used extensively for the treatment of myopathies in man and anecdotal evidence suggests it is of clinical benefit in the control of exercise-induced rhabdomyolysis (ER) in racehorses, although data to support this are currently lacking. Objective: To investigate the efficacy of oral dantrolene sodium in controlling ER in a randomised, double-blind, placebo-controlled crossover trial involving 77 Thoroughbred racehorses in Newmarket, UK. Methods: Horses were treated on 2 occasions 1 week apart, with treatment days coinciding with a return to exercise follow...
Ultrasonography of the equine cervical region: a descriptive study in eight horses.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 647-655 doi: 10.2746/042516403775696311
Berg LC, Nielsen JV, Thoefner MB, Thomsen PD.In equine patients, the cause of clinical signs possibly related to the cervical region is often difficult to diagnose. Ultrasonography allows quick and noninvasive visualisation, but reference material of the normal equine neck is needed. Objective: To describe and document the normal ultrasonographic appearance of transverse scans in the cervical region with emphasis on the synovial articular facet joints, cervical vertebrae and paravertebral structures; and further, to provide images of frozen cross-sections for anatomical reference. Methods: A study describing the normal ultrasonographic a...
Antemortem diagnosis of equine mesothelioma by pleural biopsy.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 723-727 doi: 10.2746/042516403775696375
Fry MM, Magdesian KG, Judy CE, Pusterla N, Vidal JD, Pesavento RA, Zinkl JG.No abstract available
Life-threatening hemorrhage from enterotomies and anastomoses in 7 horses.
Veterinary surgery : VS    December 3, 2003   Volume 32, Issue 6 553-558 doi: 10.1111/j.1532-950x.2003.00553.x
Doyle AJ, Freeman DE, Rapp H, Murrell JA, Wilkins PA.To report our experience with horses that presumptively had severe intraluminal hemorrhage from enterotomy or anastomosis. Methods: Clinical study. Methods: Six adult horses and 1 adult donkey. Methods: A retrospective study was conducted at the University of Illinois (April 1994 to December 2001) to determine the clinical course and outcome of horses with melena and/or anemia and evidence of life-threatening hemorrhage from intestinal incisions. Medical records of all horses that had colic surgery were reviewed to determine the proportion of horses with this complication. In addition, horses ...
Evaluation of Carolina Rinse solution as a treatment for ischaemia reperfusion of the equine jejunum.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 642-646 doi: 10.2746/042516403775696302
Dabareiner RM, White NA, Donaldson L.Ileus and peritoneal adhesions are the most common complications following surgery for small intestinal obstruction. Carolina Rinse (CR) has been shown to decrease reperfusion injury in intestine and other organs. Objective: CR decreases intestinal inflammation and subsequent scarring associated with reperfusion injury. Methods: CR was infused intra-arterially and applied topically just prior to reperfusion in jejunum exposed to experimental ischemia. Vascular permeability, neutrophil accumulation and serosal scarring were compared in treated and untreated intestine. Results: CR maintained a n...
Biomechanical investigation of the association between suspensory ligament injury and lateral condylar fracture in thoroughbred racehorses.
Veterinary surgery : VS    December 3, 2003   Volume 32, Issue 6 585-597 doi: 10.1111/j.1532-950x.2003.00585.x
Le Jeune SS, Macdonald MH, Stover SM, Taylor KT, Gerdes M.Objective-To determine whether partial transection of the medial branch of the suspensory ligament (MBSL) alters equine third metacarpal bone (MC3) condylar surface strains and forelimb, distal joint angles in a manner consistent with promotion of lateral condylar fracture. Study Design-In vitro biomechanical experiment. Sample Population-Right forelimbs from 7 Thoroughbred horse cadavers. Methods-Lateral and medial MC3 condylar, dorsal and abaxial, bone surface strains and distal joint angles were measured both before and after partial transection of the MBSL during in vitro axial limb compre...
Clinical evidence: an avenue to evidence-based medicine.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 634-635 doi: 10.2746/042516403775696267
Rossdale PD, Jeffcott LB, Holmes MA.No abstract available
Quantification and age-related distribution of articular cartilage degeneration in the equine fetlock joint.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 697-701 doi: 10.2746/042516403775696357
Brommer H, van Weeren PR, Brama PA, Barneveld A.The equine fetlock joint has the largest number of traumatic and degenerative lesions of all joints of the appendicular skeleton. Objective: To gain insight into the distribution of cartilage degeneration across the articular surface in relation to age in order better to understand the dynamic nature and progression of osteoarthritis (OA). Objective: That there would be a specific age-related distribution pattern of cartilage degeneration in the equine metacarpophalangeal joint. Methods: The proximal articular cartilage surfaces of the first phalanges (P1) of 73 slaughter horses (age range 0.4...
The effect of topical administration of atropine sulfate on the normal equine pupil: influence of age, breed and gender.
Veterinary ophthalmology    December 3, 2003   Volume 6, Issue 4 329-332 doi: 10.1111/j.1463-5224.2003.00315.x
Davis JL, Stewart T, Brazik E, Gilger BC.The purpose of this study was to determine the influence of age, breed and gender on vertical pupil diameter (VPD) following a single dose of 1% atropine sulfate ophthalmic solution in the normal equine eye. Methods: Thirty-two horses of various ages, breeds and genders were included. The horses had no history or clinical signs of ophthalmic disease. All horses studied had darkly pigmented irides. Methods: Two milligrams of 1% atropine sulfate ophthalmic solution was topically administered as a single dose in the right eye of each horse on Day 0. The VPD (mm) was measured in both eyes using di...
Complete clinical recovery of a pony with histologically confirmed chronic grass sickness.
The Veterinary record    December 3, 2003   Volume 153, Issue 19 597-598 doi: 10.1136/vr.153.19.597
Owen Ra, Kelly DF.No abstract available
Effect of GastroGard and three compounded oral omeprazole preparations on 24 h intragastric pH in gastrically cannulated mature horses.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 691-695 doi: 10.2746/042516403775696339
Merritt AM, Sanchez LC, Burrow JA, Church M, Ludzia S.Ulceration of the squamous gastric mucosa is commonly associated with intensive training programmes in horses, but only one compound ('Gastrogard') has been subjected to controlled scrutiny as to therapeutic efficacy. Objective: To compare the gastric acid inhibitory efficacy of one manufactured ('GastroGard') and 3 generic pharmacy-compounded preparations of the proton pump inhibitor omeprazole (OME) in the mature horse. Objective: All OME preparations tested would induce a clinically acceptable effect. Methods: Six healthy mature gastrically cannulated horses of various breeds, 3 mares and 3...
Superficial, nonhealing corneal ulcers in horses: 23 cases (1989-2003).
Veterinary ophthalmology    December 3, 2003   Volume 6, Issue 4 291-297 doi: 10.1111/j.1463-5224.2003.00309.x
Michau TM, Schwabenton B, Davidson MG, Gilger BC.To characterize superficial, nonhealing corneal ulcers in the horse and to assess the affect of age, breed, sex, inciting cause of the ulcer, and treatment on healing time of these ulcers. Methods: Retrospective study. Methods: Twenty-three horses with superficial, nonhealing corneal ulcerations. Methods: Medical records from 1989 to 2003 of horses diagnosed with superficial, nonhealing corneal ulcers were reviewed. Signalment, duration of clinical signs, ophthalmic abnormalities, treatment and response to treatment were recorded. Horses were treated, in addition to medical therapy, using debr...
Gender differences in bone turnover in 2-year-old Thoroughbreds.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 702-706 doi: 10.2746/042516403775696230
Jackson BF, Lonnell C, Verheyen K, Wood JL, Pfeiffert DU, Price JS.Injuries to the skeleton are a major cause of morbidity and mortality in racehorses and age, gender and season have all been shown to influence risk of injury. Objective: To use biochemical markers of bone cell activity to establish to whether cellular processes in bone underlie these described effects. Methods: Blood samples were collected monthly from 2-year-old horses in race training between November 1998 and September 1999. Mean age at the start of the study was 20 months (range 18-23 months), with no significant difference in average age between colts (n = 84) and fillies (n = 63). Three...
Effect of controlled exercise on middle gluteal muscle fibre composition in Thoroughbred foals.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 676-680 doi: 10.2746/042516403775696276
Eto D, Yamano S, Kasashima Y, Sugiura T, Nasu T, Tokuriki M, Miyata H.Most racehorses are trained regularly from about age 18 months; therefore, little information is available on the effect of training in Thoroughbred foals. Objective: Well-controlled exercise could improve muscle potential ability for endurance running. Methods: Thoroughbred foals at age 2 months were separated into control and training (treadmill exercise) groups and samples obtained from the middle gluteal muscle at 2 and 12 months post partum. Muscle fibre compositions were determined by histochemical and electrophoretical techniques and succinic dehydrogenase (SDH) activity was analysed in...
Changes in antibiotic resistance in equine bacterial ulcerative keratitis (1991-2000): 65 horses.
Veterinary ophthalmology    December 3, 2003   Volume 6, Issue 4 309-313 doi: 10.1111/j.1463-5224.2003.00312.x
Sauer P, Andrew SE, Lassaline M, Gelatt KN, Denis HM.To document changes in antibiotic resistance of organisms in cases of equine bacterial ulcerative keratitis over a 10-year time period. Methods: A retrospective study. Methods: Medical records of equine patients with bacterial ulcerative keratitis seen at the University of Florida's VMTH for the years 1991-2000 were reviewed. Methods: All cases of equine bacterial ulcerative keratitis for the above mentioned years were examined. Bacterial isolates were identified and subjected to Kirby-Bauer disc diffusion method sensitivity tests. Antibiotics used in the sensitivity tests included bacitracin,...
Accuracy of ultrasound-guided intra-articular injection of cervical facet joints in horses: a cadaveric study.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 657-661 doi: 10.2746/042516403775696366
Nielsen JV, Berg LC, Thoefnert MB, Thomsen PD.Intra-articular facet joint injection is an established diagnostic procedure in human medicine but there are no reports on its reliability in equine practice. Objective: To investigate the accuracy of ultrasound-guided intra-articular injections of the cervical facet joints and to estimate factors influencing the accuracy. Methods: Sixty injections with blue dye were performed on the facet joints between 2nd and 7th cervical vertebra (C2-C7) on horses subjected to euthanasia for nonorthopaedic reasons. The facet joints were subsequently dissected to verify accuracy of deposition. Results: Seve...
Evaluation of in vitro properties of di-tri-octahedral smectite on clostridial toxins and growth.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 638-641 doi: 10.2746/042516403775696384
Weese JS, Cote NM, deGannes RV.Clostridial colitis and endotoxaemia of intestinal origin are significant causes of morbidity and mortality in horses. Intestinal adsorbents are available for treatment of these conditions; however, little information exists supporting their use. Objective: To evaluate the ability of di-tri-octahedral smectite to bind to Clostridium difficile toxins A and B, C. perfringens enterotoxin and endotoxin, inhibit clostridial growth and the actions of metronidazole in vitro. Methods: Clostridium difficile toxins, C. perfringens enterotoxin and endotoxin were mixed with serial dilutions of di-tri-octa...
Equine passports.
The Veterinary record    December 3, 2003   Volume 153, Issue 19 604 
Robinson HC.No abstract available
Laryngoplasty with ventriculectomy or ventriculocordectomy in 104 draft horses (1992-2000).
Veterinary surgery : VS    December 3, 2003   Volume 32, Issue 6 530-538 doi: 10.1111/j.1532-950x.2003.00530.x
Kraus BM, Parente EJ, Tulleners EP.To evaluate efficacy and safety of laryngoplasty with vetriculectomy (VE) or ventriculocordectomy (VCE) for treatment of laryngeal hemiplegia (LH) in draft horses. Methods: Retrospective study. Methods: One hundred four draft horses used for competitive hitch competitions. Methods: Medical records and postoperative endoscopy for competitive hitch draft horses diagnosed with left LH and treated with laryngoplasty and VE or VCE between January 1992 and December 2000 were reviewed. Follow-up information was obtained from telephone interviews with owners and trainers, and performance scores of 1 t...
Lameness in 46 horses associated with deep digital flexor tendonitis in the digit: diagnosis confirmed with magnetic resonance imaging.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 681-690 doi: 10.2746/042516403775696294
Dyson S, Murray R, Schramme M, Branch M.The differential diagnosis of foot pain has long proved difficult and the use of magnetic resonance imaging (MRI) offers the opportunity to further the clinical understanding of the subject. Objective: To determine the incidence of deep digital flexor tendon (DDFT) injuries in a series of 75 horses with lameness associated with pain localised to the digit, with no significant detectable radiographic or ultrasonographic abnormalities, using MRI; and to describe a variety of lesion types and relate DDF tendonitis with anamnesis, clinical features, response to local analgesic techniques and nucle...