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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
[Fundamentals of hygiene to be used for stallions in an instrumental artificial insemination].
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere    August 26, 1998   Volume 26, Issue 4 218-224 
Klug E, Sieme H, Peters E.Equine artificial insemination (AI) meanwhile has been widely established in the warm blood horse industry. Because of its importance consistent hygienic aspects and their significance for the use of stallions as semen donors in AI-programs are presented and clarified. Incidence as well as importance of equine venereal infectious diseases are considered. Data of physiological bacterial genital flora and treatment principles of therapeutic control of venereal infectious bacterial agents as well as a model of control of Equine Viral Arteritis are given. A prophylactic hygiene program for donor s...
Mechanical correlations derived from segmental histologic study of the equine superficial digital flexor tendon, from foal to adult.
American journal of veterinary research    August 26, 1998   Volume 59, Issue 8 969-977 
Crevier-Denoix N, Collobert C, Sanaa M, Bernard N, Joly C, Pourcelot P, Geiger D, Bortolussi C, Bousseau B, Denoix JM.To assess histologic variations of the equine superficial digital flexor tendon (SDFT) according to site and to horse age and activity, and to correlate these data with reported segmental mechanical results. Methods: Superficial digital flexor tendons isolated from 42 horses 0.5 hour to 23 years old. Methods: 7 segments of each SDFT were delimited and submitted for conventional histologic examination. Each segment was examined and graded for fiber undulation, cellularity, number and size of interfascicular connective spaces (ICS), presence or absence of focal and diffuse chondroid metaplasia, ...
Alteration in adrenocortical function in horses with recurrent airway obstruction after aerosol and parenteral administration of beclomethasone dipropionate and dexamethasone, respectively.
American journal of veterinary research    August 26, 1998   Volume 59, Issue 8 1044-1047 
Rush BR, Worster AA, Flaminio MJ, Matson CJ, Hakala JE.To determine alteration in adrenocortical function in horses with recurrent airway obstruction (heaves) after aerosol and parenteral administration of beclomethasone dipropionate and dexamethasone, respectively. Methods: 6 horses with inducible and reversible heaves. Methods: Episodes of heaves were induced by exposure to moldy hay and straw for 7 days (natural challenge). Horses then underwent treatment (aerosolized beclomethasone, parenterally administered dexamethasone, and aerosolized propellant) for 7 days. Horses remained in the mold-contaminated environment for 7 days after discontinuat...
Effect of intravenous calcium administration on gentamicin-induced nephrotoxicosis in ponies.
American journal of veterinary research    August 26, 1998   Volume 59, Issue 8 1055-1062 
Brashier MK, Geor RJ, Ames TR, O'Leary TP.To determine whether supplemental i.v. calcium administration would attenuate or prevent gentamicin-induced acute renal failure, defined as an increase in serum creatinine concentration > or = 50% above baseline. Methods: 10 healthy pony mares. Methods: Pony mares were randomly assigned to receive calcium at a dosage of 20 mg/kg of body weight or saline solution i.v., twice daily for 14 days. All pony mares received gentamicin at a dosage of 20 mg/kg i.v. every 8 hours for 14 days. Gentamicin pharmacokinetic, serum biochemical, and urinalysis data were measured every other day for the 14-da...
Surgical treatment of oral stereotypies in horses.
The Veterinary record    August 26, 1998   Volume 143, Issue 3 87-88 
Owen RR.No abstract available
Scanning electron microscopic study of the vascular supply of the equine hoof.
The Journal of veterinary medical science    August 26, 1998   Volume 60, Issue 7 855-858 doi: 10.1292/jvms.60.855
Nasu T, Yamanaka T, Nakai M, Ogawa H.The blood supply in the equine hoof was studied by a microvascular casting corrosion technique and scanning electron microscopy in combination with observations of sections of the decalcificated digit. The dermal lamella was observed at the hoof wall and the dermal papilla at the other parts of the hoof. The microvascular architecture of the dermal lamella differed from that of dermal papilla. The vascular cast in the dermal papillar regions indicated that each papilla contained two central vessels (artery and vein), which ran parallel to each other, and the capillary plexus surrounding these ...
Organization of the equine immunoglobulin heavy chain constant region genes; III. Alignment of c mu, c gamma, c epsilon and c alpha genes.
Immunobiology    August 26, 1998   Volume 199, Issue 1 105-118 doi: 10.1016/s0171-2985(98)80067-3
Wagner B, Overesch G, Sheoran AS, Holmes MA, Richards C, Leibold W, Radbruch A.Previous restriction analysis of cloned equine DNA and genomic DNA of equine peripheral blood mononuclear cells had indicated the existence of one c epsilon, one c alpha and up to six c gamma genes in the haploid equine genome. The c epsilon and c alpha genes have been aligned on a 30 kb DNA fragment in the order 5' c epsilon-c alpha 3'. Here we describe the alignment of the equine c mu and c gamma genes by deletion analysis of one IgM, four IgG and two equine light chain expressing heterohybridomas. This analysis establishes the existence of six c gamma genes per haploid genome. The genomic a...
Pulmonary function in horses with recurrent airway obstruction after aerosol and parenteral administration of beclomethasone dipropionate and dexamethasone, respectively.
American journal of veterinary research    August 26, 1998   Volume 59, Issue 8 1039-1043 
Rush BR, Raub ES, Rhoads WS, Flaminio MJ, Matson CJ, Hakala JE, Gillespie JR.To determine changes in clinical signs of disease and response to pulmonary function testing in horses with recurrent airway obstruction (heaves) after aerosol and parenteral administration of beclomethasone dipropionate and dexamethasone, respectively. Methods: 6 horses with inducible and reversible heaves. Methods: Episodes of heaves were induced by exposure (challenge) to moldy hay and straw for 7 days. Horses were assigned to treatment groups (aerosolized beclomethasone dipropionate, parenterally administered dexamethasone, aerosolized propellant [control]), and respiratory frequency and s...
Cytologic evaluation of bronchoalveolar lavage fluid from horses with recurrent airway obstruction after aerosol and parenteral administration of beclomethasone dipropionate and dexamethasone, respectively.
American journal of veterinary research    August 26, 1998   Volume 59, Issue 8 1033-1038 
Rush BR, Flaminio MJ, Matson CJ, Hakala JE, Shuman W.To determine cytologic changes in horses with recurrent airway obstruction (heaves) after administration of aerosolized beclomethasone dipropionate and dexamethasone parenterally. Methods: 6 horses with inducible and reversible heaves. Methods: Episodes of heaves were induced by exposure to moldy hay and straw for 7 days. Horses were assigned to treatment groups (aerosolized beclomethasone, parenterally administered dexamethasone, aerosolized propellant), and pulmonary inflammation was evaluated by serial cytologic examination of bronchoalveolar lavage (BAL) fluid samples obtained on days 0, 7...
Asymmetry in placement of bilateral skin markers on horses and effects of asymmetric skin marker placement on kinematic variables.
American journal of veterinary research    August 26, 1998   Volume 59, Issue 8 938-944 
Audigié F, Pourcelot P, Degueurce C, Denoix JM, Geiger D, Bortolussi C.To evaluate asymmetry in placement of bilateral skin markers on horses and to determine effect of asymmetric skin marker placement on kinematic variables for trotting horses. Methods: 10 horses for evaluation of asymmetry in marker placement; 1 horse for evaluation of effects on kinematic variables. Methods: Asymmetry in marker placement was assessed by attaching markers to horses and comparing radiographs of left and right limbs. An experimental model was developed to determine effects on kinematic variables; accuracy of the model was validated experimentally. Using kinematic data from a clin...
Hyperglobulinemia and lymphocyte subset changes in naturally infected, inapparent carriers of equine infectious anemia virus.
American journal of veterinary research    August 26, 1998   Volume 59, Issue 8 1009-1015 
Russell KE, Walker KM, Miller RT, Sellon DC.To determine blood protein concentration, immunoglobulin concentration, and lymphocyte profiles in equine infectious anemia virus (EIAV) seropositive, naturally infected horses without clinical signs of disease. Methods: 26 clinically normal seropositive horses, 6 febrile ponies with experimentally induced EIA, and 52 clinically normal seronegative horses and ponies. Methods: Serum and EDTA-anticoagulated blood were obtained from all horses and ponies, and total serum protein and albumin concentrations, immunoglobulin concentrations, and blood lymphocyte subset counts were determined. Results:...
Virological and molecular biological investigations into equine herpes virus type 2 (EHV-2) experimental infections.
Virus research    August 26, 1998   Volume 55, Issue 1 101-106 doi: 10.1016/s0168-1702(98)00028-8
Borchers K, Wolfinger U, Ludwig H, Thein P, Baxi S, Field HJ, Slater JD.Two 18-month-old naturally reared ponies were used to investigate the pathogenicity of EHV-2. After dexamethasone treatment, pony 1 was inoculated intranasally with EHV-2 strain T16, which has been isolated from a foal with keratoconjunctivitis superficialis and pony 2 was similarly inoculated with strain LK4 which was originally isolated from a horse with upper respiratory tract disease. Following virus inoculation, pyrexia was not detected in either pony but both developed conjunctivitis, lymphadenopathy, and coughing. EHV-2 was detected in nasal mucus samples up to day 12 post infection (p....
Caveat vendor: technology and prepurchase examinations of horses.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 274-276 doi: 10.1111/j.2042-3306.1998.tb04095.x
McEvoy F, Rossdale PD, Wingfield Digby N, Lane JG.No abstract available
Increase in blood viscosity in the sprinting horse: can it account for the high pulmonary arterial pressure?
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 329-334 doi: 10.1111/j.2042-3306.1998.tb04106.x
Fedde MR, Erickson HH.Blood was taken from 49 Thoroughbred horses before and after racing at the track to determine if frusemide modified the apparent viscosity of the blood and to determine the effects of changes in shear rate and packed cell volume (PCV), associated with strenuous exercise, on apparent and relative viscosities. Small increases in apparent viscosity of the blood (at a specified PCV and shear rate) occurred in horses given frusemide compared to those receiving no frusemide; however, no differences were seen in relative viscosity. Although 2 groups of horses, those receiving frusemide before racing ...
Gastric emptying and adynamic ileus.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 278-279 doi: 10.1111/j.2042-3306.1998.tb04096.x
Evans D.No abstract available
Haemodynamic effects of a sixty minute infusion of dopamine hydrochloride in horses anaesthetised with halothane.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 310-316 doi: 10.1111/j.2042-3306.1998.tb04103.x
Young LE, Blissitt KJ, Clutton RE, Molony V.To describe the haemodynamic effects of a 60 min infusion of dopamine 4 microg/kg bwt/min during halothane anaesthesia, 7 mature Thoroughbred horses were studied. The infusion began 1 h after induction of anaesthesia by romifidine (100 microg/kg) and ketamine (2.2 mg/kg bwt). Throughout the period of dopamine infusion and for 30 min after its discontinuation, the horses were ventilated by intermittent positive pressure to maintain PaCO2 between 4.6-5.4 KPa. Inspired halothane concentration was adjusted to maintain an end tidal halothane concentration of 0.9%. Haemodynamic variables were measur...
Acetaminophen as a marker of gastric emptying in ponies.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 349-351 doi: 10.1111/j.2042-3306.1998.tb04109.x
Doherty TJ, Andrews FM, Provenza MK, Frazier DL.Gastric emptying was evaluated in ponies using the acetaminophen (AP) method. Fifteen minutes after i.v. administration of metoclopramide, erythromycin, yohimbine, atropine or saline, the ponies were given AP by stomach tube. Blood samples for AP analysis were collected at baseline and 15, 30, 45, 60, 75, 90, 105 and 120 min after AP administration. Time to reach peak serum concentration (Tmax), maximum serum concentration (Cmax) and area under the AP serum concentration vs. time curve (AUC) were determined for each treatment group. In the control group, Tmax was 31 min and this decreased sign...
Malignant Sertoli cell tumour in a horse.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 355-357 doi: 10.1111/j.2042-3306.1998.tb04112.x
Duncan RB.No abstract available
Effect of intravenous lidocaine on halothane minimum alveolar concentration in ponies.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 300-303 doi: 10.1111/j.2042-3306.1998.tb04101.x
Doherty TJ, Frazier DL.This study investigated the effect of lidocaine i.v. on halothane minimum alveolar concentration (MAC) in ponies. Six ponies were anaesthetised with thiopentone and succinylcholine, intubated and anaesthesia maintained with halothane. Ventilation was controlled and blood pressure maintained within clinically acceptable limits. Following a 2 h equilibration period, baseline halothane MAC was determined. The ponies were then given a loading dose of lidocaine (2.5 or 5 mg/kg bwt) or saline over 5 min, followed by a constant infusion of lidocaine (50 or 100 microg/kg/min, or saline, respectively)....
Absence of detectable pharmacological effects after oral administration of isoxsuprine.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 294-299 doi: 10.1111/j.2042-3306.1998.tb04100.x
Harkins JD, Mundy GD, Stanley S, Woods WE, Sams RA, Richardson DR, Grambow SC, Tobin T.Isoxsuprine is reported to be a peripheral vasodilator used in human and veterinary medicine to treat ischaemic vascular disease. In horses, it is generally administered orally to treat navicular disease and other lower limb problems. To define the scope and duration of its pharmacological responses after oral administration, 6 horses were dosed with isoxsuprine HCl (1.2 mg/kg bwt) q. 12 h for 8 days and then tested to assess the duration and extent of pharmacological actions. There was no significant difference between isoxsuprine and control treatment values for heart rate, spontaneous activ...
Glomerular filtration rate, effective renal plasma flow, blood pressure and pulse rate in the equine neonate during the first 10 days post partum.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 335-343 doi: 10.1111/j.2042-3306.1998.tb04107.x
Holdstock NB, Ousey JC, Rossdale PD.The aim of this study was to determine glomerular filtration rate (GFR), effective renal plasma flow (RPF) and filtration fraction (FF) values in Pony foals during the first 10 days post partum in order to assess any age-related changes and the reliability of the single injection inulin/p-aminohippurate (PAH) method. Arterial blood pressure and pulse rate were determined in Pony and Thoroughbred (TB) foals during the first 10 days post partum to establish age-related changes, differences between breeds and possible interrelationships with GFR and RPF. Inulin and PAH were injected intravenously...
Cardiovascular effects of surgical castration during anaesthesia maintained with halothane or infusion of detomidine, ketamine and guaifenesin in ponies.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 304-309 doi: 10.1111/j.2042-3306.1998.tb04102.x
Taylor PM, Kirby JJ, Shrimpton DJ, Johnson CB.Sixteen colts were premedicated with acepromazine and anaesthesia was induced with detomidine and ketamine. Ponies were randomly allocated to receive halothane (HAL) or infusion of detomidine, ketamine and guaiphenesin (DKG) to maintain anaesthesia. Heart and respiratory rate, ECG, mean arterial blood pressure (MABP), cardiac index (CI), blood gases and plasma cortisol, ketamine and guaiphenesin were measured. Surgical castration took place between 45 and 75 min and anaesthesia lasted 90 min. MABP with DKG was significantly higher than with HAL, and, with HAL, MABP increased from pre-surgery (...
Quantification of exercise-induced pulmonary haemorrhage with bronchoalveolar lavage.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 284-288 doi: 10.1111/j.2042-3306.1998.tb04098.x
Meyer TS, Fedde MR, Gaughan EM, Langsetmo I, Erickson HH.Exercise-induced pulmonary haemorrhage (EIPH) causes serious economic losses in the horse racing industry. Endoscopic examination indicates that 40-90% of horses exhibit EIPH following sprint exercise, but the limitations of the endoscope prevent diagnosis in many horses. Bronchoalveolar lavage (BAL) was utilised to detect red blood cells (RBCs) in the terminal airways in 6 horses. Two lavages were performed at weekly intervals prior to exercise, one within 90 min after exercise, and 5 at weekly intervals after exercise. The horses were exercised strenuously at 12.5-14.6 m/s on a treadmill (3 ...
Effect of cisapride on gastric emptying in horses following endotoxin treatment.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 344-348 doi: 10.1111/j.2042-3306.1998.tb04108.x
Valk N, Doherty TJ, Blackford JT, Abraha TW, Frazier DL.The effect of cisapride pretreatment on gastric emptying in horses was determined by measuring serum concentrations of acetaminophen, a drug known to be readily absorbed in the small intestine but not in the stomach. The time to reach maximum serum acetaminophen concentrations (Tmax), the maximum serum concentrations (Cmax) and the area under the serum acetaminophen concentration vs. time curves (AUC) were compared among treatment groups. In the first part of the study, the effect of orally administered cisapride (0.1, 0.2 and 0.4 mg/kg bwt) on gastric emptying was examined in 6 normal fasted ...
Lactalbumin-positive mammary carcinoma in a mare.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 358-360 doi: 10.1111/j.2042-3306.1998.tb04113.x
Kato M, Higuchi T, Hata H, Ishikawa Y, Kadota K.No abstract available
Low-field magnetic resonance imaging (0.2 T) of tendons with sonographic and histologic correlation. Cadaveric study.
Investigative radiology    August 15, 1998   Volume 33, Issue 8 433-438 doi: 10.1097/00004424-199808000-00002
Rand T, Bindeus T, Alton K, Voegele T, Kukla C, Stanek C, Imhof H.The authors evaluate the role of low-field strength magnetic resonance imaging (MRI) compared with sonography in the evaluation of degenerative changes of tendons, with histologic correlation, based on investigations of horse cadavers. Methods: Low-field MRI and sonography was performed in 42 hours specimens for the evaluation of tendons and ligaments. Magnetic resonance imaging included sagittal and axial T1-weighted, T2-weighted, and gradient echo images. Sonography and MR images were evaluated for degenerative changes or tears and the findings were correlated with the histologic results. Re...
Arterial blood gases and acid-base balance in healthy young and aged horses.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 352-354 doi: 10.1111/j.2042-3306.1998.tb04111.x
Aguilera-Tejero E, Estepa JC, López I, Mayer-Valor R, Rodríguez M.No abstract available
A questionnaire survey on nematode control practices on horse farms in Denmark and the existence of risk factors for the development of anthelmintic resistance.
Veterinary parasitology    August 15, 1998   Volume 78, Issue 1 49-63 doi: 10.1016/s0304-4017(98)00117-4
Lendal S, Larsen MM, Bjørn H, Craven J, Chriél M, Olsen SN.A questionnaire survey to obtain information on endoparasite control practices and management on 68 Danish horse farms was undertaken in 1995. The study revealed that foals, young horses and adults were on average, annually treated 4.3, 4.0 and 3.7 times, respectively. The most commonly used drug from 1993-1995 was ivermectin. On average 2.4 different drugs were used annually. The most used method of weight estimation was eye measure: for foals by 78%, for youngsters by 81% and adults by 82% of the herd owners. The most commonly used weight in the dosing of anthelmintics was individual weights...
Serum gentamicin concentrations in compromised neonatal foals.
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 324-328 doi: 10.1111/j.2042-3306.1998.tb04105.x
Raisis AL, Hodgson JL, Hodgson DR.Twenty-one compromised neonatal foals hospitalised at the Rural Veterinary Centre (RVC) during 1993 were studied to determine i) serum gentamicin concentrations obtained when gentamicin was administered at 3.3 mg/kg bwt twice daily i.m.; ii) factors which contributed to inter-foal variation in serum gentamicin concentrations achieved and iii) clinical efficacy of gentamicin therapy in foals with confirmed septicaemia. Septicaemia was confirmed in 7 foals with positive blood cultures and suspected in 8 foals with a sepsis score > 11. Peak serum concentrations (Ps) were > 6 microg/ml in al...
Is anthelmintic resistance inevitable: back to basics?
Equine veterinary journal    August 15, 1998   Volume 30, Issue 4 280-283 doi: 10.1111/j.2042-3306.1998.tb04097.x
Lloyd S, Soulsby .No abstract available