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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
[Heart rate fluctuations in the horse at rest: (2) Biological variation factors related to behavioural profile].
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie    August 1, 1995   Volume 318, Issue 8 867-872 
Clément F, Barrey E.Variability of heart rate was analysed within a sample of 30 horses in order to determine the influence of factors (animal, age, sex and breed) associated with different behavioural patterns. The heart rate fluctuations were analysed by computing the power spectral density of a series of heartbeat intervals. A generalized linear model was used to compare the spectra and to reveal the effect of each factor: animal age, sex and breed. The scale and shape of spectral densities were significantly different between animals. This individual variability was partly explained by the sex and age effects...
Ligaments associated with joints.
The Veterinary clinics of North America. Equine practice    August 1, 1995   Volume 11, Issue 2 249-291 doi: 10.1016/s0749-0739(17)30322-x
Wright IM.This article contains a short introduction to the anatomy, physiology, and pathophysiology of ligaments associated with diarthrodial joints. Individual ligaments are discussed on a regional basis as forelimb, distal limb, and hindlimb. Emphasis is placed on the anatomy of the ligaments because this is the key to sound clinical application of their involvement in joint disease. There are few conditions of diarthrodial joints that do not involve their associated ligaments, and this role may be in causative, diagnostic, and therapeutic or convalescent considerations.
[Hypoproteinemia].
Tierarztliche Praxis    August 1, 1995   Volume 23, Issue 4 325-327 
Kraft W.No abstract available
Detection of African horse sickness viruses by dot-blot hybridization using a digoxigenin-labelled probe.
Molecular and cellular probes    August 1, 1995   Volume 9, Issue 4 233-237 doi: 10.1016/s0890-8508(95)90092-6
Moulay S, Zientara S, Sailleau C, Cruciere C.In order to develop a non-radioactive dot-blot hybridization assay, for the detection of African-horse sickness virus (AHSV), genome segment 7 from 9 serotypes was amplified by RT-PCR. The resulting PCR products were denatured, immobilized on nylon membranes and then hybridized to a non-radioactive digoxigenin-labelled probe. This probe (265 bp in length) was generated by nested-PCR using genome segment 7 of AHSV, serotype 4 as a template. The dot-blot was visualized by chemiluminescence. Positives were obtained from the PCR products amplified from all 9 AHSV serotypes, but not from any other ...
Partial sequence of the equine immunoglobulin epsilon heavy chain cDNA.
Veterinary immunology and immunopathology    August 1, 1995   Volume 47, Issue 3-4 363-367 doi: 10.1016/0165-2427(94)05404-g
Marti E, Szalai G, Bucher K, Dobbelaere D, Gerber H, Lazary S.In order to isolate a part of the immunoglobulin E (IgE) heavy chain cDNA of the horse, primers have been designed based upon well conserved sequences in humans, sheep and rats. The PCR resulted in a 500 bp fragment which hybridised with a human IgE constant region probe. The fragment was cloned and sequenced and its derived protein sequence compared with the corresponding sequences in humans, sheep and mice. Most amino acids common to these three species are also shared by the horse.
[Bilateral obstructive ecstasy of the kidneys in a newborn foal: a case study].
Tierarztliche Praxis    August 1, 1995   Volume 23, Issue 4 394-397 
Rapp HJ, Jost H, Stechele M, Becker M.A report is given of obstructive ectasy of both kidneys in a newborn foal. Diagnosis and therapy are described as well as differential diagnosis.
Hyperkalaemic periodic paralysis in Australian quarter horses.
Australian veterinary journal    August 1, 1995   Volume 72, Issue 8 314-316 doi: 10.1111/j.1751-0813.1995.tb03563.x
Church S.Three Quarter Horse stallions and 5 of their 11 tested progeny were diagnosed as affected with the inherited autosomal dominant defect hyperkalaemic periodic paralysis in Victoria in 1992. The diagnoses were based on the appearance of clinical signs and associated increased plasma potassium concentrations in response to oral potassium loading. All affected horses were descendants of the American Quarter Horse Impressive. Indirect evidence indicates that at least 3 other affected Quarter Horse stallions have stood or are standing at stud in Australia. The clinical details of the affected horses...
Equine arteritis virus-neutralizing antibody in the horse is induced by a determinant on the large envelope glycoprotein GL.
The Journal of general virology    August 1, 1995   Volume 76 ( Pt 8) 1989-1998 doi: 10.1099/0022-1317-76-8-1989
Chirnside ED, de Vries AA, Mumford JA, Rottier PJ.Complementary DNAs encoding ORFs 2 to 7 equine arteritis virus (EAV) have been cloned into the expression vector pGEX to produce glutathione-S-transferase fusion proteins. Recombinant proteins were affinity purified and screened in ELISA with equine sera to identify immunoreactive polypeptides. The large envelope glycoprotein (GL) was identified as the most reactive to EAV-positive equine sera and an immuno-dominant epitope was mapped between amino acids 55 and 98 by subcloning and expression. A fusion protein covering this region and a GL-specific synthetic peptide (residues 75 through 97) in...
Monoclonal antibodies specific for equine IgG sub-isotypes including an antibody which recognizes B lymphocytes.
Veterinary immunology and immunopathology    August 1, 1995   Volume 47, Issue 3-4 239-251 doi: 10.1016/0165-2427(95)97067-j
Lunn DP, Holmes MA, Schram B, Duffus WP.Equine immunoglobulin G is currently classified as consisting of five sub-isotypes: IgGa, b, and c, IgG(T), and IgG(B). The study of the role of these immunoglobulins in antigen-specific responses, and the examination of their functional properties would be greatly facilitated by the availability of monoclonal antibodies (Mabs) that distinguish between them. The production and characterization of two Mabs that recognize an IgG sub-isotype with the characteristics of IgG(ab) is described. The immunoglobulin identified by these Mabs had a heavy chain weight of 53 kDa, was of rapid cathodal elect...
Pharmacokinetics of heparin and its pharmacodynamic effect on plasma lipoprotein lipase activity and coagulation in healthy horses.
American journal of veterinary research    August 1, 1995   Volume 56, Issue 8 1070-1074 
McCann ME, Watson TD, Boudinot FD, Moore JN.We evaluated the pharmacokinetics of IV administered sodium heparin and the pharmacodynamic effect of heparin on lipoprotein lipase (LPL) activity. Horses were allotted to 3 groups. Plasma samples were obtained from each horse before and at various times for 6 hours after heparin administration for determination of heparin concentration, LPL activity, and activated partial thromboplastin time (APTT). The disposition of heparin was dose dependent. The area under the plasma heparin concentration vs time curve (AUC) increased more than proportionally with dose, indicating that heparin elimination...
Tendon, tendon sheath, and ligament injuries in the pastern.
The Veterinary clinics of North America. Equine practice    August 1, 1995   Volume 11, Issue 2 217-233 doi: 10.1016/s0749-0739(17)30320-6
Dyson SJ, Denoix JM.The palmar (plantar) aspect of the pastern is an anatomically complex area and an understanding of this is a prerequisite for accurate diagnosis of injuries in this area. The gross and normal ultrasonographic anatomy are described, and injuries of the superficial and deep digital flexor tendons and the digital flexor tendon sheath, the distal sesamoidean ligaments, and the palmar ligaments of the proximal interphalangeal joint are discussed.
Cytokine modulation alters pulmonary clearance of Rhodococcus equi and development of granulomatous pneumonia.
Infection and immunity    August 1, 1995   Volume 63, Issue 8 3037-3041 doi: 10.1128/iai.63.8.3037-3041.1995
Kanaly ST, Hines SA, Palmer GH.Rhodococcus equi, a facultative intracellular bacterium, causes chronic, often fatal granulomatous pneumonia in young horses and in humans with AIDS. The inability of host alveolar macrophages to kill intracellular R. equi results in the development of granulomas and progressive loss of pulmonary parenchyma. Clearance of the organism from the lung requires functional CD4+ T cells. The purpose of this study was to identify the cytokine effector mechanisms that mediate clearance of R. equi from the lung. Mice were treated with monoclonal antibodies (MAbs) to either gamma interferon (IFN-gamma) o...
Suspensory ligament desmitis.
The Veterinary clinics of North America. Equine practice    August 1, 1995   Volume 11, Issue 2 177-215 doi: 10.1016/s0749-0739(17)30319-x
Dyson SJ, Arthur RM, Palmer SE, Richardson D.The gross and functional anatomy of the suspensory ligament (SL) and its ultrasonographic variability are described. Injuries of the suspensory apparatus are divided into lesions confined to the proximal one third of the metacarpus or metatarsus (proximal suspensory desmitis and avulsion fractures), lesions of the body, and branch lesions. Complete breakdown injuries are also discussed. In view of the close association of the SL, the second, third, and fourth metacarpal or metatarsal bones, and the proximal sesamoid bones, associated bony lesions are also considered.
Miscellaneous conditions of tendons, tendon sheaths, and ligaments.
The Veterinary clinics of North America. Equine practice    August 1, 1995   Volume 11, Issue 2 315-337 doi: 10.1016/s0749-0739(17)30324-3
Dyson SJ, Dik KJ.The use of diagnostic ultrasonography has greatly enhances our ability to diagnose injuries of tendons and tendon sheaths that were previously either unrecognized or poorly understood. For may of these injuries, there is currently only a small amount of follow-up data. This article considers injuries of the deep digital flexor tendon and its accessory ligament, the carpal tunnel syndrome soft tissue swellings on the dorsal aspect of the carpus, intertubercular (bicipital) bursitis and bicipital tendinitis, injuries of the gastrocnemius tendon, common calcaneal tendinitis, rupture of peroneus (...
Plasma melatonin in the horse: measurements in natural photoperiod and in acutely extended darkness throughout the year.
Journal of pineal research    August 1, 1995   Volume 19, Issue 1 7-15 doi: 10.1111/j.1600-079x.1995.tb00165.x
Guerin MV, Deed JR, Kennaway DJ, Matthews CD.Plasma melatonin was measured at the winter and summer solstices and the autumn and spring equinoxes in four mares held under natural conditions at 35 degrees S. At all seasons the onset of the nightly elevated melatonin was coincident with or after the time of sunset and the melatonin offset after the time of sunrise. The duration of elevated melatonin was not different from the duration of natural scotophase for each season, with the duration of elevated melatonin longer in winter than the other seasons. Immediately following each 24 hr sampling two mares were resampled in acutely extended d...
Comparison of time-resolved fluoroimmunoassay and immunoenzymometric assay for clenbuterol.
The Analyst    August 1, 1995   Volume 120, Issue 8 2269-2271 doi: 10.1039/an9952002269
Bacigalupo MA, Ius A, Meroni G, Dovis M, Petruzzelli E.A time-resolved fluoroimmunoassay (TR-FIA) for the direct determination of clenbuterol residues in horse urine using a highly specific monoclonal antibody has been compared with an immunoenzymometric assay (IEMA). The sensitivity of both methods was 10 pg; the calibration curve was linear between 10 and 10(5) pg for the TR-FIA and between 10 and 10(4) pg for the IEMA.
Investigations on preileal digestion of starch from grain, potato and manioc in horses.
Zentralblatt fur Veterinarmedizin. Reihe A    August 1, 1995   Volume 42, Issue 6 371-381 doi: 10.1111/j.1439-0442.1995.tb00389.x
Meyer H, Radicke S, Kienzle E, Wilke S, Kleffken D, Illenseer M.In this study preileal starch digestibility of starchy feeds (oats, corn, barley, potatoes, manioc) was determined in seven jejunofistulated horses. The grains were fed whole (oats, corn), rolled (oats, barley), crushed, ground and expanded (corn); the potatoes were fresh, the manioc rolled. Ground corn was also fed in combination with amylase. The feeds were fed partly isolated or in combination with alfalfa meal or hay (Table 1). At least four horses with a cannula in the terminal jejunum were used for each diet. Two meals per day were offered at 12 h intervals. The starch intake was mostly ...
Klossiella equi infection in horses; sporocyst stage identified in urine.
Australian veterinary journal    August 1, 1995   Volume 72, Issue 8 316-318 doi: 10.1111/j.1751-0813.1995.tb03564.x
Reppas GP, Collins GH.No abstract available
Microscopic anatomy of the equine skin with special reference to the dermis.
Okajimas folia anatomica Japonica    August 1, 1995   Volume 72, Issue 2-3 177-183 doi: 10.2535/ofaj1936.72.2-3_177
Wakuri H, Mutoh K, Ichikawa H, Liu B.We have observed and re-evaluated the histology of the skin of the horse, using samples from four Thoroughbreds. The skin was composed of the usual three components: epidermis, dermis and subcutis. In particular, the dermis was found to have three fibrous components: a papillary layer, a reticular layer and a cordovan-leather tissue layer. The cordovan-leather tissue layer was subdivided into a superficial main layer and a deeper accessory layer. The superficial main layer was thick, and present in all of the skin samples. The deeper accessory layer was found in the dorsal and dorso-lateral pa...
Pulsatile gonadotropin secretion determined by frequent sampling from the intercavernous sinus of the mare: possible modulatory role of progesterone during luteolysis.
Biology of reproduction    August 1, 1995   Volume 53, Issue 2 438-446 doi: 10.1095/biolreprod53.2.438
Silvia PJ, Meyer SL, Fitzgerald BP.Twelve horse mares were used in a repeated-measures design consisting of 3 replicates of 4 mares each. On Day 6 following ovulation, luteolysis was initiated with an i.m. injection of prostaglandin F2 alpha (PGF2 alpha; Lutalyse, 10 mg). Either 12 (-12) or 36 (-36) h before PGF2 alpha (PRE), blood samples were collected simultaneously from the intercavernous sinus (ICS) and jugular (JUG) vein at 10-min intervals for an 8-h period. Pituitary capacity to exogenous GnRH (2 micrograms/kg BW, i.v.) was evaluated at the alternate time point within this period. Frequent sampling and GnRH challenge we...
An equine microsatellite repeat at the VIAS-H64 locus.
Animal genetics    August 1, 1995   Volume 26, Issue 4 282 doi: 10.1111/j.1365-2052.1995.tb03263.x
Ewen KR, Matthews ME.No abstract available
Uterine torsion associated with small intestinal incarceration in a mare at 126 days of gestation.
Journal of the American Veterinary Medical Association    August 1, 1995   Volume 207, Issue 3 329-330 
Ruffin DC, Schumacher J, Comer JS.A mare at 126 days of gestation was examined because of signs of abdominal pain. The cause of abdominal pain could not be determined by physical examination. Lack of response to analgesics and small intestinal distention on palpation per rectum prompted exploratory celiotomy. Small intestine was found to be entrapped by the uterus, which had undergone torsion. The uterus was returned to its correct position, and the small intestine was decompressed. After surgery, the mare was treated with orally administered progestin to prevent abortion. The mare recovered and delivered a live foal at 354 da...
Incidence of multiple ovulation and multiple pregnancy in mares.
The Veterinary record    July 29, 1995   Volume 137, Issue 5 121-123 doi: 10.1136/vr.137.5.121
Newcombe JR.No abstract available
An evaluation of the accuracy of ageing horses by their dentition: changes of dental morphology with age.
The Veterinary record    July 29, 1995   Volume 137, Issue 5 117-121 doi: 10.1136/vr.137.5.117
Richardson JD, Cripps PJ, Lane JG.Dental features are commonly expected to provide an accurate estimate of a horse's age. In this study the dentition of 434 thoroughbreds was photographed and the individual dental features documented, the true age of all the horses was known. For each dental feature the correlation with true age was determined. The eruption of the incisor teeth was the most consistent feature but it was not totally reliable. The presence of a hook on the upper corner incisor and Galvayne's groove proved to be of no value when estimating age and, of the attritional features studied, the dental star showed the h...
Cloning and analysis of the cDNA encoding the horse and donkey luteinizing hormone beta-subunits.
Gene    July 28, 1995   Volume 160, Issue 2 253-256 doi: 10.1016/0378-1119(95)00150-5
Chopineau M, Stewart F, Allen WR.The coding regions of the horse (Equus caballus) and donkey (E. asinus) luteinizing hormone (LH) beta-subunit transcripts were cloned from pituitary gland RNA, in order to investigate their relationships to the corresponding equine chorionic gonadotropin (CG) beta-subunits and to further understand the unusual receptor-binding properties of equine LH and CG. The horse and donkey LH beta-subunit sequences were very similar (97% identity at the nucleotide (nt) level; 93% at the amino acid (aa) level), confirming their very close evolutionary linkage and also indicating that the C-terminal extens...
An evaluation of the accuracy of ageing horses by their dentition: a matter of experience?
The Veterinary record    July 22, 1995   Volume 137, Issue 4 88-90 doi: 10.1136/vr.137.4.88
Richardson JD, Cripps PJ, Hillyer MH, O'Brien JK, Pinsent PJ, Lane JG.There is a widely held belief that a horse can be accurately aged by an examination of its teeth but this belief has recently been questioned. In this study photographs were taken of the dentition of 434 thoroughbreds of known age. Four experienced equine clinicians provided estimates of the ages of the horses from the photographs. A comparison of the estimated and true ages showed large discrepancies in many cases and the discrepancies increased as the horse's true age increased. The results show that the ageing of horses from their dentition is an imprecise science. It is suggested that writ...
Removal of chip fractures of the femoral trochlear ridges of three horses by arthroscopy.
The Veterinary record    July 22, 1995   Volume 137, Issue 4 94-96 doi: 10.1136/vr.137.4.94
Montesso F, Wright IM.Clinical and radiographic examinations of three horses with histories of trauma and/or wounds to the stifle revealed chip fractures from the medial trochlear ridge of the femur of one of them and from the lateral ridges of the femurs of the others. The joints were evaluated and the fragments of bone were removed by arthroscopy. The results were good in all three horses.
Chyloabdomen in a neonatal foal.
The Veterinary record    July 22, 1995   Volume 137, Issue 4 96-98 doi: 10.1136/vr.137.4.96
Campbell-Beggs CL, Johnson PJ, Wilson DA, Miller MA.A 12-hour-old female standardbred foal developed signs of abdominal pain, tachycardia, tachypnoea and fever associated with chylous ascites. Small intestinal obstruction was due to segmental, mid-jejunal lymphangiectasia. Post mortem examination revealed a lack of communication between afferent and efferent lymphatic vessels in the mesenteric lymphocentre, a defect which was suspected to be congenital.
The effects of tyrphostins B42 and B46 on equine platelet function and protein tyrosine phosphorylation.
Biochemical and biophysical research communications    July 17, 1995   Volume 212, Issue 2 595-601 doi: 10.1006/bbrc.1995.2011
Dillon AM, Heath MF.The effects of the protein tyrosine kinase inhibitors tyrphostins B42 and B46 on equine platelet function and protein tyrosine phosphorylation (PTP) were assessed. Tyrphostins B42 and B46 (both at 100 microM concentration) produced significant inhibition of thrombin-stimulated equine platelet aggregation. The effect of tyrphostin B46 was also time-dependent. The same concentration of these inhibitors produced very little or no inhibition of platelet-activating factor (PAF)-induced aggregation. The effects of tyrphostins B42 and B46 on thrombin- and PAF-stimulated PTP were generally similar, al...
Outbreak of vesicular dermatitis among horses at a midwestern horse show.
Journal of the American Veterinary Medical Association    July 15, 1995   Volume 207, Issue 2 211-213 
Campagnolo ER, Trock SC, Hungerford LL, Shumaker TJ, Teclaw R, Miller RB, Nelson HA, Ross F, Reynolds DJ.Dermatitis consisting of blisters on the nose and other parts of the body was reported among horses at a Midwestern horse show. Some horses also had jaundice, hematuria and anorexia. An outbreak investigation was initiated, and of 239 horses for which information could be obtained, 58 (24%) were found to have been affected. Median duration of illness was 5 days, and all horses recovered. Age, sex, water source, grain source, and stabling location were not associated with illness. The use of wood shavings bedding obtained at the show grounds was the factor most strongly associated with the deve...