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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Fumonisins: their implications for human and animal health.
Natural toxins    January 1, 1995   Volume 3, Issue 4 193-221 doi: 10.1002/nt.2620030405
Marasas WF.Fusarium moniliforme is one of the predominant fungi associated with corn intended for human and animal consumption world-wide. Fumonisins, food-borne carcinogens that occur naturally in corn, were first isolated and chemically characterized in South Africa in 1988. The major metabolite, fumonisin B1 (FB1), was subsequently shown to cause leukoencephalomalacia (LEM) in horses, pulmonary edema syndrome (PES) in pigs, and liver cancer in rats. FB1 is also a cancer promoter and initiator in rat liver; hepatotoxic to horses, pigs, rats, and vervet monkeys; cytotoxic to mammalian cell cultures; and...
In vitro assessment of two species of nematophagous fungi (Arthrobotrys oligospora and Arthrobotrys flagrans) to control the development of infective cyathostome larvae from naturally infected horses.
Veterinary parasitology    January 1, 1995   Volume 56, Issue 1-3 181-187 doi: 10.1016/0304-4017(94)00663-w
Bird J, Herd RP.The ability of two species of nematophagous fungi, Arthrobotrys oligospora and Arthrobotrys flagrans (syn. Trichothecium flagrans, Duddingtonia flagrans), to control the development of infective larvae in feces from naturally infected horses was assessed in vitro. The horses were from a farm where it had been previously established that cyathostomes accounted for 100% of the strongyle egg output. The feces from these naturally infected horses were mixed with spores of each fungal species at four concentrations: 0 (control), 1, 10, and 100 spores per egg. Five replicates for each group were inc...
Flow-cytometric studies of the phagocytic capacities of equine neutrophils.
Acta veterinaria Scandinavica    January 1, 1995   Volume 36, Issue 4 553-562 doi: 10.1186/BF03547669
Johannisson A, Gröndahl G, Demmers S, Jensen-Waern M.Methodological aspects of flow-cytometric evaluation of the phagocytic properties of equine neutrophils were elucidated. The kinetics of attachment and ingestion were studied, and the phagocytic process was more rapidly completed when serum-opsonized yeast cells were used than with use of IgG-opsonized yeast cells. Trypan blue was successfully used to quench fluorescence of non-ingested yeast cells. There were only minor differences in the kinetics of phagocytosis between quenched and unquenched samples, indicating that attachment is rapidly followed by ingestion. Trypan blue quenching caused ...
Stress failure of pulmonary capillaries as a limiting factor for maximal exercise.
European journal of applied physiology and occupational physiology    January 1, 1995   Volume 70, Issue 2 99-108 doi: 10.1007/BF00361536
West JB, Mathieu-Costello O.The pulmonary blood-gas barrier has a basic physiological dilemma. On the one hand it needs to be extremely thin for efficient gas exchange. On the other hand it also needs to be immensely strong because the stresses on the pulmonary capillary wall become extremely high when the capillary pressure rises on exercise. Maximal hydrostatic pressures in human pulmonary capillaries during exercise are not accurately known but must exceed 30 mmHg. In some animals, for example thoroughbred horses, the capillary pressure rises to about 100 mmHg. These pressures cause stresses in the capillary wall of 5...
Postoperative myositis in a neonatal foal: a case report.
Veterinary surgery : VS    January 1, 1995   Volume 24, Issue 1 69-72 doi: 10.1111/j.1532-950x.1995.tb01298.x
Manning M, Dubielzig R, McGuirk S.A foal with azotemia, acidemia, and electrolyte abnormalities was diagnosed with uroperitoneum. The foal was anesthetized with isoflurane, and throughout the 4 hours of anesthesia and abdominal surgery, its mean arterial pressure ranged between 45 and 65 mm Hg. The foal developed a myopathy postoperatively and died 24 hours after surgery.
Prostaglandin F2 alpha metabolite levels following an embryo transfer procedure in the mare.
Acta veterinaria Scandinavica    January 1, 1995   Volume 36, Issue 1 145-147 doi: 10.1186/BF03547711
Kask K, Malmgren L, Odensvik K.Hormonal, chemical, and mechanical stimuli can activate the arachidonic acid cascade and result in formation of prostaglandins and related substances. These compounds can have a profound role in the initiation of the inflammatory process (Higgins & Lees 1984). Prostaglandin (PG) F2α is the key hormone in reproductive physiology with well-known effects on reproductive performance e.g. luteolysis and abortion. An activation of the arachidonic acid cascade, caused by mechanical manipulation during an embryo transfer procedure, might be one explanation for early embryonic loss.
Major histocompatibility complex class I-restricted cytotoxic T-lymphocyte responses in horses infected with equine herpesvirus 1.
Journal of virology    January 1, 1995   Volume 69, Issue 1 606-612 doi: 10.1128/JVI.69.1.606-612.1995
Allen G, Yeargan M, Costa LR, Cross R.An experimental system that permits sensitive and reproducible detection of equine herpesvirus 1 (EHV-1)-specific cytotoxic T-lymphocyte (CTL) activity in the horse was developed. Peripheral blood mononuclear cells (PBMC) collected from immune horses were restimulated in vitro by culture with live EHV-1. Cytotoxic activity against virus-infected, pokeweed mitogen-stimulated lymphoblast targets was assessed in a 4-h 51Cr release assay. The optimal conditions for in vitro stimulation of equine memory CTLs and for preparation of EHV-1-infected target cells expressing viral antigens were systemati...
Capacitation in vitro of stallion spermatozoa: comparison of progesterone-induced acrosome reactions in fertile and subfertile males.
Journal of andrology    January 1, 1995   Volume 16, Issue 1 47-54 
Meyers SA, Overstreet JW, Liu IK, Drobnis EZ.Mammalian sperm that have completed capacitation are capable of undergoing the acrosome reaction in response to a number of biological and chemical stimuli. In the present report, we have investigated the ability of progesterone to stimulate acrosome reactions of stallion sperm capacitated in vitro. Motile sperm were selected by a two-layer Percoll gradient centrifugation and were incubated in TALP medium modified by the 1:1 (v/v) addition of TEST-yolk medium for 5 hours at 39 degrees C, under 5% CO2 in humidified air. Sperm incubated in vitro in TALP-TEST medium had a higher percentage of acr...
Endothelial lipopigment as an indicator of alpha-tocopherol deficiency in two equine neurodegenerative diseases.
Acta neuropathologica    January 1, 1995   Volume 90, Issue 3 266-272 doi: 10.1007/BF00296510
Cummings JF, de Lahunta A, Mohammed HO, Divers TJ, Summers BA, Valentine BA, Jackson CA.Two spontaneous neurodegenerative diseases of the horse, equine motor neuron disease (EMND) and equine degenerative myeloencephalopathy (EDM), have been associated with alpha-tocopherol deficiency, and both were characterized by prominent accumulations of endothelial lipopigment in the small vessels of the spinal cord. These endothelial pigment deposits appear to be reversible. In EMND horses pasture-supplemented for 9 months or more after the progression of weakness and wasting had arrested, there was very little endothelial lipopigment. The origin and the potential effects of these endotheli...
[Differentiation between glanders and melioidosis].
Klinicheskaia laboratornaia diagnostika    January 1, 1995   Issue 1 47-48 
Dunaev GS, Lobanov AN, Larionov GM, Britanova AL.No abstract available
A note on the concurrent isolation, from horses and ponies, of influenza A/EQ-1 and A/EQ-2 viruses from an epidemic of equine influenza in India.
Comparative immunology, microbiology and infectious diseases    January 1, 1995   Volume 18, Issue 1 73-74 doi: 10.1016/0147-9571(94)00015-m
Singh G.A/eq-1 and A/eq-2 influenza viruses were isolated simultaneously from an epidemic of equine influenza in north India. Evidently, both types of equine influenza viruses circulated in the equine population at the same time.
Fetal and maternal plasma lipids in chronically catheterized mares in late gestation: effects of different nutritional states.
Reproduction, fertility, and development    January 1, 1995   Volume 7, Issue 5 1275-1284 doi: 10.1071/rd9951275
Stammers JP, Hull D, Silver M, Fowden AL.The effects of different nutritional states on plasma lipid concentrations have been examined in pregnant mares and their fetuses. Maternal and fetal arterial catheters were inserted into 12 pony mares between 244-303 days' gestation (term 320-360 days) and observations made from 5 days following the insertion of catheters. After recovery from surgery maternal and fetal arterial samples were withdrawn from 7 mares with normal feeding patterns (Group IA), from four of these mares at the end of a 30 h fast and 3 h later following refeeding (Group IB) and six mares who failed to re-establish norm...
[Military veterinary service and the formation of veterinary medicine and farriery in the 19th century].
Schweizer Archiv fur Tierheilkunde    January 1, 1995   Volume 137, Issue 1 5-10 
Krähenmann A.No abstract available
[2 cases of severe closed trauma to the duodenum].
Khirurgiia    January 1, 1995   Volume 48, Issue 4 59-60 
Kiurkchiev P, Kiurkchiev G.No abstract available
Equine parentage testing and DNA technology–the route forward?
The British veterinary journal    January 1, 1995   Volume 151, Issue 1 1-3 doi: 10.1016/s0007-1935(05)80054-5
Knapp MR, Goelet P.No abstract available
The prevalence and epidemiology of Anoplocephala perfoliata infection in Norway.
Veterinary research communications    January 1, 1995   Volume 19, Issue 6 487-494 doi: 10.1007/BF01839337
Ihler CF, Rootwelt V, Heyeraas A, Dolvik NJ.The caecum and the adjacent 30 cm lengths of ileum and large colon of 201 horses from two different regions of Norway (Ostlandet and Trøndelag) were examined for the presence of Anoplocephala perfoliata. In all, 20% of the horses were infested with the cestode (27% in Ostlandet and 7% in Trøndelag). The mean number of worms in infected horses from the two regions was 18 and 6, respectively. Information was obtained on the age, sex, breed, type of pasture and anthelmintic treatment after the grazing season for 183 of the 20 horses. The degree of infestation with A. perfoliata was not influenc...
Isolation of a compound from Eupatorium adenophorum (Spreng.) [Ageratina adenophora (Spreng.)] causing hepatotoxicity in mice.
Natural toxins    January 1, 1995   Volume 3, Issue 5 350-354 doi: 10.1002/nt.2620030505
Oelrichs PB, Calanasan CA, MacLeod JK, Seawright AA, Ng JC.Regular ingestion of Eupatorium adenophorum [Ageratina adenophora (Spreng.)] or Crofton weed causes chronic pulmonary disease in horses mainly in Australia, New Zealand, and the Himalayas. The disease is characterized by pulmonary interstitial fibrosis, emphysema, alveolar epithelisation and reduced tolerance to exercise. Horses apparently are the only animals affected and there are numerous reports of farms losing all their horses. The disorder was produced experimentally in horse feeding trials, and it was shown that characteristic lesions occurred in the lungs. In studies with laboratory an...
Use of sodium monoiodoacetate to fuse the distal hock joints in horses.
Australian veterinary journal    January 1, 1995   Volume 72, Issue 1 25-28 doi: 10.1111/j.1751-0813.1995.tb03471.x
Sammut EB, Kannegieter NJ.Intra-articular injection of sodium monoiodoacetate (MIA) was investigated as an agent for chemical arthrodesis of the distal hock joints in the horse. Five horses diagnosed with either spavin (three horses), a small tarsal bone fracture or a failed surgical arthrodesis, had 150 mg of MIA injected into the tarsometatarsal (TMT) joint of the affected hock(s). Eight joints were treated in the five horses. Follow-up evaluation by clinical and radiological examination took place over 9 to 14 months. Two of the five horses were sound at the conclusion of the study and one horse, although lame after...
Spermatophagy in the stallion epididymis: a scanning and transmission electron microscopy study.
Acta anatomica    January 1, 1995   Volume 153, Issue 3 181-188 
López Alvarez ML, Bustos Obregón E.The occurrence of phagocytosis of spermatozoa in the epididymis is a controversial issue in male reproductive biology. In this paper we documented, by scanning and electron microscopy, the presence of spermatophages in the lumen of the proximal region of stallion epididymis. Sperm phagocytosis involving the principal cells that line the cauda epididymidis region was also observed. The possible meaning of this process in the removal of damaged, aged or surplus spermatozoa is discussed. These observations were made in samples obtained from random cases, during the course of research work carried...
The identification of polymorphic microsatellite loci in the horse and their use in thoroughbred parentage testing.
The British veterinary journal    January 1, 1995   Volume 151, Issue 1 9-15 doi: 10.1016/s0007-1935(05)80057-0
Binns MM, Holmes NG, Holliman A, Scott AM.Six new horse microsatellite loci were identified by sequencing M13 clones containing horse genomic inserts which gave positive signals when probed with a CA/GT repeat probe. Oligonucleotide primer pairs were synthesized for these loci and for two previously described horse microsatellites, HTG4 and HTG6. Polymerase chain reaction assays were then carried out on a panel of 20 different unrelated Thoroughbred horse DNAs. DNAs from eight cases of double covering which could not be solved by conventional blood typing were also examined. Several of the loci amplified were found to be polymorphic a...
Diffuse alveolar damage in the horse.
Equine veterinary journal    January 1, 1995   Volume 27, Issue 1 76-78 doi: 10.1111/j.2042-3306.1995.tb03037.x
Kelly DF, Newsholme SJ, Baker JR, Ricketts SW.No abstract available
Response of ponies to adjuvanted EHV-1 whole virus vaccine and challenge with virus of the homologous strain.
The British veterinary journal    January 1, 1995   Volume 151, Issue 1 27-37 doi: 10.1016/s0007-1935(05)80061-2
Dolby CA, Hannant D, Mumford JA.Five yearling ponies were vaccinated with inactivated Equid herpesvirus type 1 (EHV-1) in Freund's complete adjuvant as a double emulsion and revaccinated 6 weeks later with EHV-1 in Freund's incomplete adjuvant. These ponies and three age-matched controls were challenged intra-nasally after a further 6 weeks with homologous live virus and monitored clinically, biologically and serologically. After challenge, clinical signs were mild in both groups. No cell-associated viraemias were detected in vaccinated ponies. Vaccination induced high levels of complement-fixing (CF) and virus-neutralizing ...
Activity of praziquantel (0.5 mg kg-1) against Anoplocephala perfoliata (Cestoda) in equids.
Veterinary parasitology    January 1, 1995   Volume 56, Issue 1-3 255-257 doi: 10.1016/0304-4017(94)00661-u
Lyons ET, Tolliver SC, Stamper S, Drudge JH, Granstrom DE, Collins SS.Praziquantel injectable formulation was administered at 0.5 mg k-1 per os to 24 equids naturally infected with 1-183 (average 40) Anoplocephala perfoliata. Drug activity was evaluated by a modified critical test method with necropsy 24 h after treatment. There was variable efficacy of 0-100% (aggregate average 85%); for 18 equids, 93-100%, for three equids, 70-85%, and for three equids, 0-20%.
Outbreak of larval cyathostomiasis among a group of yearling and two-year-old horses.
The Veterinary record    December 17, 1994   Volume 135, Issue 25 598-600 
Mair TS.Larval cyathostomiasis was diagnosed as the cause of an outbreak of illness in a group of five young horses. One had the typical clinical signs of larval cyathostomiasis--sudden onset diarrhoea, weight loss, ventral abdominal oedema and pyrexia, but the other four suddenly started to lose weight rapidly and had limb and ventral abdominal oedema and pyrexia, in the absence of diarrhoea. Large numbers of cyathostome larvae were found in the faeces. Four of the five horses recovered after being treated with anthelmintics and steroids.
Evaluation of factors associated with postoperative ileus in horses: 31 cases (1990-1992).
Journal of the American Veterinary Medical Association    December 15, 1994   Volume 205, Issue 12 1748-1752 
Blikslager AT, Bowman KF, Levine JF, Bristol DG, Roberts MC.Medical records of horses that underwent surgical treatment for colic between 1990 and 1992 were reviewed. Horses with a pulse rate of > or = 60 beats/min or signs of abdominal pain, which were also accompanied by a volume of > 2 L of material that refluxed from the stomach during the postoperative period (excluding horses with anterior enteritis), comprised the postoperative ileus (POI) group. Horses that had < 2 L of material reflux during the postoperative period and survived > 3 days after surgery comprised the reference population. The association of preoperative and intraoperative clinic...
Pleural effusion associated with acute and chronic pleuropneumonia and pleuritis secondary to thoracic wounds in horses: 43 cases (1982-1992).
Journal of the American Veterinary Medical Association    December 15, 1994   Volume 205, Issue 12 1753-1758 
Collins MB, Hodgson DR, Hutchins DR.Case records of 43 horses with pleural effusion associated with acute pleuropneumonia, chronic pleuropneumonia, or pleuritis secondary to a penetrating thoracic wound were reviewed to determine the predisposing factors, diagnosis, and treatment of this condition. Acute pleuropneumonia was diagnosed in 36 horses, the majority of which were Thoroughbreds (89%). Of 22 (61%) horses that were in race training at the onset of illness, 11 (31%) had been recently transported a long distance and 4 (11%) had evidence of exercise-induced pulmonary hemorrhage. Physical examination findings and hematologic...
[Differential diagnosis of non-healing ‘fungal’patches in horses].
Tijdschrift voor diergeneeskunde    December 15, 1994   Volume 119, Issue 24 756-759 
Sloet van Oldruitenborgh-Oosterbaan MM, Klein WR, Misdorp W.Dermatophytosis is the most common equine skin disease. Mycotic-like lesions that do not disappear are suspected of being sarcoids. The clinical symptoms and therapeutic interventions for both affections are discussed. A short review of the differential diagnoses is presented.
Emergence of eastern encephalitis in Massachusetts.
Annals of the New York Academy of Sciences    December 15, 1994   Volume 740 157-168 doi: 10.1111/j.1749-6632.1994.tb19866.x
Komar N, Spielman A.The 20th century emergence in Massachusetts of zoonotic eastern encephalitis was interpreted in terms of recorded environmental change. The main mosquito vector of the infection, Cs. melanura, appears to have been scarce in eastern North America before the 1930s. Its relative scarcity resulted from destruction of the swamps that had been lumbered or drained for farming in the 18th and 19th centuries. When swamps matured once again early in the 1900s, the formation of subsurface pools of water beneath mature trees would have increased the availability of breeding sites for this mosquito. Transm...
Evaluation of a modification of the Hudson demand valve in ventilated and spontaneously breathing horses.
The Veterinary record    December 10, 1994   Volume 135, Issue 24 569-572 
Johnson CB, Adam EN, Taylor PM.Hypoxaemia commonly develops during general anaesthesia and in the recovery period in horses. The Hudson demand valve has been used to increase arterial PO2, but it has been found to increase airway resistance considerably when used during spontaneous ventilation. This paper evaluates a modification of the valve designed to reduce this resistance. The effects of the valve and its modification on arterial oxygen (PaO2), and carbon dioxide (PaCO2) tensions were evaluated in four ponies anaesthetised by a total intravenous technique. The valve increased PaO2 from 8.3 +/- 1.1 to 32.7 +/- 7.6 kPa d...
Optimal nutrition for athletic performance, with emphasis on fat adaptation in dogs and horses.
The Journal of nutrition    December 1, 1994   Volume 124, Issue 12 Suppl 2745S-2753S doi: 10.1093/jn/124.suppl_12.2745S
Kronfeld DS, Ferrante PL, Grandjean D.Four mathematical approaches are proposed to determine optimal ranges of nutrients for specified purposes. For exercise, the diet must provide optimal mixtures of fuels, also optimal amounts of nutrients conducive to a sound structure, a desired power/weight ratio, a water-electrolyte system that resists dehydration and buffers hydrogen ions, a tolerance to the cumulative stress of repetitive competition and tractable attitude. The nutritional strategy of carbohydrate loading risks a variety of abnormalities in dogs and horses. An alternative strategy of fat adaptation (the combination of fat ...